2008

KetonesQ 0350 Asymmetric Direct Aldol Reaction of Functionalized Ketones Catalyzed by Amine

Organocatalysts Based on Bispidine. — DAA derived from bispidine and L-phenyl-alanine is highly selective for the aldol reaction of acetone with α-keto phosphonates, α-keto esters, and α,α-dialkoxy ketones. — (LIU, J.; YANG, Z.; WANG, Z.; WANG, F.; CHEN, X.; LIU, X.; FENG, X.; SU, Z.; HU*, C.; J. Am. Chem. Soc. 130 (2008) 17, 5654-5655; Coll. Chem., Sichuan Univ., Chengdu, Sichuan 610064, Peop. Rep. China; Eng.) — Klein

35- 072

2008