NHM 2: 1.Nguyn Th Lan Anh 2.Nguyn Th Sen 3.L Cng Lc 09/05/1991
14/06/1993 25/05/1993 10001273 11000536 11002355 11010661 11000321
11000294 11000715 11000774 11000186 11000085 11000255 11000647
4.Nguyn Th Thanh Tm 12/03/1993 5.Ngyn Th Khuyn 6.Ngyn Th Lan Hng
7.Nguyn Th Hi Yn 8.Hong Th Thun 9.Nguyn Th Thu Hng 10.Cao Th Dinh
11.Nguyn Th Hu 12.Phm Qunh Trang 08/12/1993 09/02/1993 04/05/1992
08/04/1993 02/12/1993 24/10/1993 15/08/1993 02/10/1993
A.MNG LI NI CHT. --c tm thy hu ht cc t bo ng vt (tr hng cu chn),
nguyn sinh thc vt (amip,tho trng ), t bo ca tt c thc vt ( tr to
lam) -Ring vi khun khng c mng li sinh cht I.Cu trc, hnh thi. -Mng
li ni cht c cu trc nh l mt h thng ng dn chng cht v pht trin rng khp
t bo cht, c nng bi h thng khung xng ca t bo. -Bao gm h thng cc knh,
cc ti, cc b cha phn ph trong t bo cht v c gii hn bi mng
lipoproteit. -Cc knh ti v b cha thng vi nhau hnh thnh nn mng li ba
chiu phc tp, phn b khp t bo cht ca t bo
-Ty
loi t bo m c tnh cu trc v mc pht trin ca mng li ni cht thay i
.Mng li ni cht pht trin nht cc t bo ang phn ha v cc t bo ang tch cc
tng hp cht. -Mng li ni cht pht trin mnh nht cc t bo c mc trao i
protein cao nh cc t bo tit, t bo gan. -i vi cc loi t bo nh tinh bo,
bch cu , t bo v tuyn trn thn th mng li ni cht pht trin yu . -Mng
bao bc ngoi ca mng li ni cht c cu to gn nh mng c s: l mng kp gm hai
mng lipoprotein bao bc xoang c cht gia. Tu vo trng chc nng v s gn
vi cc riboxom m mng li ni cht c hai vng c trng: mng li ni cht trn v
mng li ni cht ht Mng li c ht Mng li trn (khng c ht)
Gm mt h thng ti dt xp song song L mt h thng ng phn nhnh thnh
nhm. thng thng vi mng li ni cht c - Mng bao bc ngoi l mng ht,mng
nhn,ty th, peroyxom ging mng sinh cht nhng t l protein - Mng bao bc
ngoi ca h thng v lipit ln hn so vi t l mng ng l mng sinh cht ni bo.
sinh cht. - T l gia lipit v protein vn nh - Trong s cc lipit phc tp
tham mng ca mng li c ht nhng s gia cu to th cholesteron chim t l
lng cholesteron cao hn. thp; photphattidycholin chim trn - Trn mng
v bn trong ng c 50%; cc enzim nh glucoz-6- nhiu enzim tng hp cc
lipit phc tp photphataza, nucleotit-photphataza, nn ni no c tng hp
lipit mnh m glucosytransferaza, cc thnh vin enzim th h thng mng li
ni cht tham gia qu trnh thu phn. khng ht pht trin. - Trn mng ca h
thng ti dt bm dnh nhiu riboxom. cc loi t bo c tng hp protein mnh th
s lng riboxom cng nhiu.
Li ni cht trn thng vi li ni cht ht.
1.Nhn , 2.L nhn, 3.Mng li ni cht ht, 4.Mng li ni cht trn,
5.Riboxom 6.Cc phn t protein c vn chuyn, 7.Ti tit vn chuyn protein,
8.Th gogli 9.u cis ca th golgi, 10.u trans ca th golgi, 11.Phn thn
ca th golgi II.Thnh phn ha hc ca mng li ni cht. -Mng ca mng li ni
cht c cha cc protein cu trc v cc lipit (3050%), cc enzym cn thit
cho s tng hp protein, s trao i cc lipit v kh c. -Mng theo m hnh khm
ng
-Mng ca mng li ni cht c tnh bt i xng. Phn ca gluxit ca cc
glicolipit v glicoproteit u hng vo lng ti. *S sai lch ga 2 mng li.
Thnh phn Photpholipit T l photpholipit/cholesteron Enzym
gluco-6-photphatase Mng li ni cht ht Cha t 1.5 c Mng li ni cht trn
Cha nhiu 4.0 khng c
III.Chc nng. *Vai tr giao thng ni bo: -m bo vn chuyn cc cht t mi
trng vo t bo cht , v cng l ng giao thng gia cc cu trc ni bo -Mng li
chuyn ng tch cc ui hoc thu ht cc cht khc nhau vo xoang, b cha v thu
nhn khng phi th ng m c chn lc -Vai tr tp trung cht: cc cht khc nhau
t t bo cht hoc t cc bo quan c tp trung vo cc xoang, ti, b cha ca
mng li ni cht ri t chuyn i n cc phn khc nhau ca t bo hoc thi ra
ngoi. *Vai tr tng hp cht: -Tham gia vo qu trnh tng hp cc cht -Mng
li ni cht ht: tham gia qu trnh tng hp protein khc nhau c bit l cht
tit protein, zymogen =>pht trin mnh trong cc t bo chu trch nhim
sn xut cc ch phm protein -Mng li ni cht trn: tham gia vo qu trnh vn
chuyn cc cht khc c bit l lipit phc tp, photpholipit , lipoteit pht
trin mnh cc t bo tng hp lipit -Mng li ni cht trn kh c, chng tp
trung v chuyn ha cc c t xm nhp vo t bo. IV.Ngun gc v pht trin.
-Ngun gc c th l mng sinh cht -Mng li ni cht c th c ngun gc t mng
nhn. B.PHC H GOLGI. I.Hnh thi -Dng mng li phc tp xp xung quanh t bo
-Dng cu, dng lim, dng que ng ring l -Dng phn tn (thng gp t bo ng vt
c xng sng)
-Hnh dng ca phc h golgi khc nhau cc loi t bo v thay i ty theo
hot tnh chc nng ca t bo. -Phc h golgi c cu trc rt a dng v c tnh d
thy i (dng li c th thnh dng phn tn v ngc li II.Cu trc siu hin vi.
-C cu to mng lipoproteit, chiu dy 75, nhn, khng c ribosome bm mt
ngoi. -Gm 3 thnh phn: +H thng b cha dp gii hn bi cc mng trn, xp
thnh b 5- 8 b st nhau. S lng b cha dp v khong cch gia chng thay i
ty loi t bo v chc nng ca phc h golgi +Nhng khng bo b nm cui cc b.
+Khng bo ln c mng bao bc nh b cha thng nm cnh cc b b cha hoc xen
gia cc b trong b.Cc cu thnh ca phc h c lin h vi nhau, c ngun gc lin
quan ti nhau -Mc pht trin ca cc cu thnh cc loi t bo khc nhau l khc
nhau. Cc cu thnh ca phc h golgi u lin h vi nhau c ngun gc lin kt
nhau Khng bo b
