Abstract Collection
第三届先进凝胶材料与软物质国际学术讨论会
The 3rd International Symposium for Advanced Gel Materials & Soft Matters
Jun. 14-17, 2019 Xi’an, China
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
2
PL 1
Future Subjects of Gel Science---inspired from biology................................................................... 1
PL 2
Functional Hydrogels Constructed from Natural Polymers .............................................................. 2
PL 3
DNA hydrogels ................................................................................................................................. 3
PL 4
Self-growing hydrogels by repetitive mechanical training ............................................................... 4
PL 5
Low-molecular Mass Compounds-based Gels and Gel Emulsions: From Aerogels to High
Performance Porous Monoliths ......................................................................................................... 5
PL 6
Photo-reactive polymers for medical applications ............................................................................ 6
PL 7
Mechanical stability of fiber networks .............................................................................................. 7
IL1-1
Polyampholyte Hydrogels with pH Modulated Shape Memory and Spontaneous Actuation ........... 8
IL1-2
Hydrogels with ultra-dynamic network enhance mechanosensing-dependent activities of
encapsulated stem cells ..................................................................................................................... 9
IL1-3
Mussel inspired cell/tissue adhesive hydrogels with multi-functions ............................................. 10
IL1-4
Underwater Microphones: Electric Double Layers at the Electrode-Gel Interface......................... 11
IL1-5
Bioinspired nucleobase-driven adhesive hydrogels with excellent underwater adhesion ............... 12
IL1-6
Mechanical reinforcement of soft matter: design of synthetic gels as model systems .................... 13
IL1-7
Bioinspired Chiral Supramolecular Hydrogels ............................................................................... 14
IL1-8
Multifunctional hydrogels for rapid hemostasis and tissue repair .................................................. 15
IL2-1
Highly Plasticized PVC Gel with Smart Functions Electrical, Optical, Mechanical - .................... 16
IL2-2
High Frequency dynamics of polymer solutions and gels studied by microrheology ..................... 17
IL4-1
Anisotropic composite gels from liquid crystalline nanosheets ...................................................... 18
IL4-2
Biomimetic shape-transformation of composite hydrogel films ..................................................... 19
IL 4-3
Active Gap Control of Gold Nanodots using Gels in Nanoscale .................................................... 20
IL 4-4
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
3
Anomalous expansion of clusters in percolation process in diluted system ................................... 21
IL 5-1
Ion-to-Ion Amplification through an Open Junction 1 Ionic Diode Jeong-Yun Sun ....................... 22
IL5-2
Active network of motor proteins as artificial dynamic microenvironment for cells ..................... 23
IL5-3
Functional modification, Controllable Fabrication and Biomedical Applications of natural polymer
Hydrogel ......................................................................................................................................... 24
IL5-4
Ultrastretchable Stress and Strain Sensors Based on Tough Conductive Hydrogels ...................... 25
IL5-5
Instabilities in soft materials: from gels to metamaterials ..................................................... 26
IL5-6
Stimuli-Responsive Smart Membranes ........................................................................................... 27
IL5-7
Construction of molecular swarm robot integrating biomolecular soft actuators and processors ... 28
IL5-8
Polysaccharide-based ionic hydrogel .............................................................................................. 29
OL 1-1
Super-elastic and multifunctional polymer hydrogel strengthened by low-content cement-released
nanoparticles ................................................................................................................................... 30
OL 1-2
OSA-AM hydrogel with high-strength and faster self-healing property from sodium alginate...... 31
OL 1-3
High Strength Globular Protein Hydrogels ..................................................................................... 32
OL 1-4
Multiple Functions of High Performance Hydrogels Enhancement by Hydrogen Bond ................ 33
OL 1-5
Predictions of Thermo‐Mechanical Properties of Cross‐Linked Polyacrylamide Hydrogels Using
Molecular Simulations .................................................................................................................... 36
OL 1-6
Solvent responsive ultra-strong shape memory gels based on hydrophobic association with fantasy
applications ..................................................................................................................................... 38
OL 1-7
Electroactive Hydrogels: synthesis, characterization and application ............................................ 39
OL 1-8
Highly-tough single-network polysaccharide hydrogel .................................................................. 40
OL 1-9
Molecular engineering of metal-coordination interactions for strong, tough and fast-recovery
hydrogels ......................................................................................................................................... 42
OL 1-10
Injectable Hydrogel Formed by Metal–Ligand Coordination Assembly as Biomaterials ............... 43
OL 1-11
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
4
Fabrication of chitosan functionalized graphene oxide-embedded nanocomposite hydrogels with
enhanced mechanical properties ..................................................................................................... 45
OL 1-12
Freezing-Tolerant Gelatin Organohydrogels with High Mechanical Performances,
Thermoplasticity, and Adhesivity .................................................................................................... 46
OL 1-13
Electrochemical analysis of bovine serum albumin imprinting CaAlg based composite hydrogel
sensor .............................................................................................................................................. 48
OL 1-14
Ultrastiff and tough hydrogels with dense and robust hydrogen bond complexes .......................... 49
OL 1-15
Anisotropic All-Cellulose 3D Wrinkled Hydrogels with Programmable Patterns for Cells
Alignment ....................................................................................................................................... 50
OL 1-16
An injectable self-assembling collagen-gold hybrid hydrogel for combinatorial antitumor
photothermal/photodynamic therapy .............................................................................................. 51
OL 1-17
PAM/CaAlg/CaSiO3@SiO2 composite hydrogel with high strength, good transparency and low
swelling under physiological environment ..................................................................................... 53
OL 1-18
Multicolor Fluorescent Polymeric Hydrogels: Fabrication and Sensing/Actuating applications ... 54
OL 1-19
Mechano-responsive, tough and antibacterial zwitterionic hydrogels with controllable drug release
for wound healing ........................................................................................................................... 56
OL 1-20
Macroscopic Supramolecular Assembly of Hydrogels Based on Host/Guest Polymer Brushes .... 57
OL 1-21
Natural Triterpenoid-Tailored Phosphate: In Situ Reduction of Heavy Metals Spontaneously to
Generate Electrochemical Hybrid Gels ........................................................................................... 58
OL 1-22
High-strength and Self-Healing Hydrogel Based on Carboxymethylcellulose ............................... 59
OL 1-23
Ultrastiff and Tough Supramolecular Hydrogels with a Dense and Robust Hydrogen Bond
Network........................................................................................................................................... 60
OL 1-24
Alginate-based hydrogel microcapsules for immobilized biocatalysis ........................................... 61
OL 2-1
Natural triterpene-tailored supramolecular gels: chiral transfer and amplification ......................... 62
OL 2-2
The “Morse Code” between Solvent Polarity and Morphology Flexibility .................................... 63
OL 2-3
Hierarchical Macroporous networks construct by Supramolecular chiral self-assembly of POSS
core dendrimers ............................................................................................................................... 64
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
5
OL 3-1
Nanocellulose Based Bio-scaffold Routed For Biomedical Applications ....................................... 65
OL 3-2
Controlled Self-Assembly of MXene-Polymer at Liquid/Liquid Interfaces ................................... 66
OL 3-3
“Stiff-Soft” Binary Synergistic Aerogels with Superflexibility and High Thermal Insulation
Performance .................................................................................................................................... 67
OL 3-4
Highly Porous Polymer Aerogel Film - Based Triboelectric Nanogenerators ................................ 68
OL 3-5
Graphene-crosslinked CNT aerogel for the preparation of elastic porous polymer composites ..... 69
OL 3-6
The Organic Acids Assisted Sol-Gel Method for Preparing Functional Aerogels .......................... 70
OL 3-7
Mesoporous Silica Nanoparticles as Nanocarriers for Controlled Pesticide Release ..................... 71
OL 4-1
Achieving Fracture-resistant Composite Hydrogels by Large Energy-dissipative Process Zones . 72
OL 4-2
Bio-inspired hydrogel/organogel materials with special adhesion .................................................. 74
OL 4-3
Mussel-Inspired Cellulose Nanocomposite Tough Hydrogels with Synergistic Self-Healing,
Adhesive, and Strain-Sensitive Properties ...................................................................................... 75
OL 4-4
Hollow hydrogel networks for temperature-controlled water fluidics ............................................ 76
OL 4-5
Deswelling behavior of pNIPAM composite gel consisting of nanosheet liquid crystal whose
orientation is controlled by asymmetric electric field ..................................................................... 77
OL 4-6
Strong and tough hydrogels with highly ordered and controllable microstructure ......................... 78
OL 5-1
Structural constructions and multi-functions of biodegradable polyurethanes ............................... 79
OL 5-2
Inducing Molecular Isomerization Assisted by Water..................................................................... 81
OL 5-3
Rational design of UCST polymers as functional materials guided by a thermodynamic map ...... 82
OL 5-4
Biocompatible photoluminescent silk fibers with stability and durability ...................................... 83
OL 5-5
From Shear-thickening Gel to Multifunctional Anti-impact Body Armor ..................................... 84
OL 5-6
A self-healing hydrogel with pressure sensitive photoluminescence for remote force measurement
and healing assessment ................................................................................................................... 86
OL 5-7
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
6
Controlled Phase Transitions of Dipeptide-based Gels ................................................................... 87
OL 5-8
Histidine-based Supramolecular π-gel: Dynamic Self-assembly and Controlled Switching of
Circularly Polarized Luminescence ................................................................................................ 88
OL 5-9
Biomimetic anisotropic hydrogel actuators..................................................................................... 89
OL 5-10
Bioinspired Soft Sensing and Actuating Materials ......................................................................... 90
OL 5-11
Hydrophobic Hydrogels with Fruit-like Structure and Functions ................................................... 91
P 1-1
Investigation of photo-crosslinkable injectable poly(vinyl alcohol) hydrogel for cartilage repair . 92
P 1-2
A highly stretchable conductive polymer hydrogel by freeze-thaw- shrink treatment for flexible
electrodes ........................................................................................................................................ 93
P 1-3
Peptide nanofiber hydrogels to vascularization in skin regeneration .............................................. 94
P 1-4
Anti-freezing ZwitterionicPoly(ionic liquid) hydrogel-based multimodal artificial skin ............... 95
P 1-5
Synthesis and properties of a Tough and multifunctional hydrogel based on grape seed polymer
........................................................................................................................................................ 96
P 1-6
Physically cross-Linked hydrogel with toughness, high stretchability, biocompatibility,
conductivity, and self-healability .................................................................................................... 97
P 1-7
Reverse Photochromic hydrogel with self-healing property for potential rewritable display
application ....................................................................................................................................... 98
P 1-8
CO2 sensitive self-supporting cellulose hydrogel as food spoilage indicator ................................. 99
P 1-9
Flexible semi-IPN network gel polymer electrolyte for supercapacitor ....................................... 100
P 1-10
All-in-one configured stretchable flexible supercapacitor with high strength, excellent
self-recovery and self-healing performances ................................................................................ 101
P 1-11
Complex Deformation of Bilayer Hydrogels Based on Shape Memory Hydrogel and Elastic
Hydrogel ....................................................................................................................................... 102
P 1-12
Hybrid Cross-linked Natural Protein Hydrogels with High Strength ........................................... 103
P 1-13
Body-Temperature Responsive Ultrafast Shape Memory Hydrogel Based on Natural Materials
...................................................................................................................................................... 104
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
7
P 1-14
One-Step Synthesis of Healable Weak-Polyelectrolyte-Based Hydrogels with High Mechanical
Strength, Toughness, and Excellent Self-Recovery ...................................................................... 105
P 1-15
Preparation and Properties of Nanocomposite Hydrogels Cross-linked by Alumina Nanoparticles
...................................................................................................................................................... 106
P 1-16
Tough hydrogels with strong, fast and reversible underwater adhesion........................................ 107
P 1-17
A Highly stretchable, tough and fast self-healing hydrogel based on peptide-metal ion
coordination .................................................................................................................................. 108
P 1-18
Asymmetric interpenetrating UCST polymer network as multiple-responsive hydrogel actuator 109
P 1-19
A shape memory hydrogel with editable permanent shape based on orthogonal supramolecular
interactions .................................................................................................................................... 110
P 1-20
Color-Tunable Fluorescent Supramolecular Metallogels Constructed by Lanthanide (Eu/Tb)
Dependent Coordination Interaction ............................................................................................. 111
P 1-21
Tough Lignin Bonded Hydrogels with Tunable Mechanical Properties ....................................... 112
P 1-22
Reinforcement of gelatin hydrogel by heat-induced phase separation .......................................... 113
P 1-23
Dual physically cross-linked double network hydrogel with high toughness and self-healing
capability ....................................................................................................................................... 114
P 1-24
Control of ice crystal growth and its effect on porous structure of chitosan cryogels .................. 115
P 1-25
In-situ forming thermosensitive polyurethanes-based hydrogel crosslinked by Diels-Alder reaction
for 3D cell culture ......................................................................................................................... 116
P 1-26
Shape memory hydrogel based on sodium alginate crosslinked by double networks................... 117
P 1-27
Highly adhesive and stretchable photothermal hydrogels for preventing postoperative recurrence
of cancer ........................................................................................................................................ 118
P 1-28
Sulfonated MXene Nanocomposite Hydrogels for Self-healing, Adhesive and Conductive
Properties ...................................................................................................................................... 119
P 1-29
Research on Gel Analyzer Based on Image Processing ................................................................ 120
P 1-30
Preparation of keratin-based polymer hydrogel with double sensitivity for drug releasing ......... 121
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
8
P 1-31
Facile preparation and enhanced stretchableperformance of self-assembled polyelectrolytes-based
composite hydrogels ..................................................................................................................... 122
P 1-32
Tough, antibacterial and antifouling double network hydrogels based on hybrid ionic-covalent
crosslinking* ................................................................................................................................. 124
P 1-33
Double cross-linking the second network of DN hydrogel for tough sensitive strain and pressure
sensors ........................................................................................................................................... 125
P 1-34
Synthesis and swelling properties of superporous anionic hydrogel based polyvinyl
alcohol-formaldehyde sponges ..................................................................................................... 127
P 1-35
Biotribology behavior of UHMWPE grafted with PVA/HA composite hydrogel as artificial
cartilage materials ......................................................................................................................... 128
P 1-36
Internal Damage Evolution in Double-Network Hydrogels Studied by Microelectrode Technique
...................................................................................................................................................... 130
P 1-37
Programmed deformations of 3D printed tough physical hydrogels with metal-coordination
complexes ..................................................................................................................................... 131
P 1-38
Programmed multi-stable configurations of composite hydrogels with in-plane and
through-thickness gradients .......................................................................................................... 132
P 1-39
Mechanical Property of Polyelectrolyte Networks ....................................................................... 133
P 2-1
Adhesive, self-healable, and transparent micro-crosslinked organogels as flexible sensor .......... 134
P 2-2
Highly Stretchable, Electrically Conductive and Temperature Tolerant Ionogels for Flexible
Sensors .......................................................................................................................................... 135
P 2-3
A Shorter Alkyl Chain Dominated Self-Assembly of Homochiral Nanotubes in Heterochiral Lipid
Organogels .................................................................................................................................... 137
P 2-4
Anti-freezing, non-drying tough organohydrogel with good flexibility and conductivity ............ 138
P 2-5
Organic or inorganic crystallization in functional molecular gels ................................................ 139
P 3-1
Oil-water separation, Lightweight, Flexible and Thermally-Insulating Aerogels Derived from
wood Nanofibrillated Cellulose .................................................................................................... 140
P 3-2
Preparation and characterization of ultra-fast Temperature-responsive nanofibrous hydrogel ..... 142
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
9
P 3-3
Cu/Cu2O/CuO Nanoparticles Loaded on Porous Carbon from a Novel Hypercrosslinked Porous
Polymer for Catalytic Reduction of 4-Nitrophenol ....................................................................... 143
P 3-4
Synthesis of leafy-shape TiO2-C nanosheets by alkaline treatment of Ti3C2Tx MXene ............... 144
P 3-5
Removal of Perrhenate using Radiation Synthesized Hierarchically Macro/Mesoporous
Silica-gratft-Quaternary Phosphonium ......................................................................................... 146
P 3-6
Zein-based composite film with pH-sensitivity for drug controlling release ................................ 148
P 3-7
Zein-based magnetic polymer aerogel as oil absorbing agent ...................................................... 149
P 3-8
Microstructure and mechanical properties of aerogels prepared by Freeze casting ...................... 150
P 3-9
Controlled preparation of Nitrogen-doped carbon cryogels with excellent carbon dioxide
adsorption performance ................................................................................................................. 151
P 4-1
Ionically Cross-Linked Silk Microfibers/Alginate Tough Composite Hydrogels with Hierarchical
Structures ...................................................................................................................................... 152
P 4-2
Effects of zein on the formation of konjac glucomannan electrospun nanofibres for controlled
release of curcumin ....................................................................................................................... 159
P 4-3
Zein-based composite film with pH-sensitivity for drug controlling release ................................ 160
P 4-4
Synthesis of self-supporting composite nanowires based on 3D-network metallogel template ... 161
P 5-1
Freeze and Heat-Resistant, Nonflammable and Highly Robust Ionic Liquid-Based Click-Ionogels
...................................................................................................................................................... 162
P 5-2
Molecular dynamics simulation of rupture mechanism in nanofiller filled polymer nanocomposites
...................................................................................................................................................... 163
P 5-3
Research and application of implantable blood detection device based on shape memory polymer
...................................................................................................................................................... 165
P 5-4
Stretchable resistance sensor based on liquid metal direct writing method .................................. 166
P 5-5
Ionoprinting controlled information storage of fluorescent hydrogel for hierarchical and
multidimensional decryption ......................................................................................................... 167
P 5-6
Multifunctional Wearable Sensors based on Repairable and Recyclable Carbon Nanotubes
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
10
Conductive Hydrogel .................................................................................................................... 168
P 5-7
Autonomous swarming of biomolecular robots utilizing the sequential signaling of DNA ......... 169
P 5-8Super-elastic and multifunctional polymer hydrogel strengthened by low-content cement-released nanoparticles ..................................................................................................................................170
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
1
PL 1
Future Subjects of Gel Science---inspired from biology
Yoshihito OSADA
RIKEN, Wako, Saitama, 351-0198, Japan
Gel is a main constituent of biology and its science is extremely wide and
borderless spreading to life science. One of the ultimate goals of gel science is to
create hydrogels with “Emergent Functions” which biological soft tissues possess and
eventually to replace them. In this connection, we have to learn real structure to
reveal their functions from biology.
In this talk several important research subjects in gel science to be investigated
in future will be given. They include some of the following topics.
1 Mechanically Strong Hydrogel with Tissue- like Structure
2 Mechanism and Creation of Bio-Interface
3 Water in the Gel -- Its Unusual behaviors
4 Nano-kinetics in the Gel
5 Emergent Function through Hierarchical Gel
6 Ionics and Electronics
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
2
PL 2
Functional Hydrogels Constructed from Natural Polymers
Lina Zhang*, Xichao Liang, Dongdong Ye, Kunkun Zhu, Jiangjiang Duan
College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072,
China.
Faced on the increasing consumption of non-renewable fossil resources and the
increasingly serious environmental pollution caused by non-degradable plastics,
renewable biomass polymers show great application prospects, because their safety
and biodegradability. We have developed new solvents, alkali/urea aqueous solutions
with cooling, to dissolve cellulose, chitin and chitosan, resulting in a transparent
natural solution. Herein, by reducing nanofibrous formation through the “bottom to
up” method, a series of cellulose, chitin and chitosan based functional hydrogels were
successfully constructed as follows. (1) Novel chitosan/carrageenan polyelectrolyte
composite hydrogels with high strength and toughness were constructed based on the
electroneutral behavior of chitosan in alkali/urea aqueous solvent system, showing the
application prospects in the cartilage repair. (2) Bilayer hydrogels with temperature
and pH responses were prepared by utilizing the pH sensitivity of chitosan hydrogel.
(3) Mechanically strong nanofibril-structured chitosan hydrogel was fabricated via
simply drawing, which can guide directional growth of the cells. (4) A robust and
conductive hydrogel with high strength, ultra-stretchability and force-sensitivity was
fabricated through multiple interpenetrating networks in the chitosan microspheres,
which could be an ideal candidate for electronic skin devices. (5) Chitin hydrogels
cross-linked with epichlorohydrin in alkali/urea aqueous solution were used for the
soilless cultivation of rapeseed, showing good seed germination and growth. (6)
Robust anisotropic cellulose hydrogels were fabricated from cellulose solution
through pre-stretching strategy in chemical gel state and then locking the highly
ordered nanostructure via strong self-aggregation forces, which could induce the
directional growth of cardiomyocytes. These natural polymer-based functional
hydrogels have potential applications in the fields of biomedicine, sensor and
agriculture etc.
Acknowledgements This work was supported by the Major International (Regional)
Joint Research Project of National Natural Science Foundation of China
(21620102004).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
3
PL 3
DNA hydrogels
Dan Luo, PhD, Professor
Cornell University, Ithaca, NY 14850, USA
Believing in the concept that DNA is a true polymer. over the last almost 20 years,
my group at Cornell University has been engineering DNA molecules as both a
genetic and a generic building block. Indeed, DNA is an amazing polymer with more
than four thousand nanoscale processing tools that no other polymers have. In this talk,
I will focus on how we have designed and developed DNA-based hydrogels for
real-world applications from diagnostics to pharmaceutics. More specifically, I will
elaborate on the creation of the first-ever, all-DNA hydrogel and from which a
protein-producing DNA hydrogel (termed P-gel). Besides the chemical crosslinked
DNA hydrogels, a physical, entangled DNA hydrogel was also invented in my group.
This type of DNA hydrogel has the meta-property in that the hydrogel is both a liquid
and a solid. Our DNA P-gel may lead towards the realization of synthetic cells while
our meta-DNA hydrogel may become a super condensed ultra-compact DNA
(scudDNA) for the direct delivery of DNA-based therapeutics. Recently, we have also
created a new type of hydrogel: life-like DNA hydrogels that possessed metabolic
activities while at the same time were able to move autonomously against flow. Two
such DNA hydrogels raced against each other. Other novel, large scale DNA
hydrogels will also be discussed. We envision that DNA hydrogels will become an
important, versatile, and sustainable material for the world in the near future.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
4
PL 4
Self-growing hydrogels by repetitive mechanical training
Takahiro Matsuda1, Ryo Namba1, Tasuku Nakajima2,3,4, Jian Ping Gong2,3,4
(1Graduate School of Life Science, Hokkaido University; 2Faculty of Advanced Life Science,
3Soft Matter GI-CoRE, 4WPI-ICReDD, Hokkaido University, Japan. )
Living tissues, such as muscle, autonomously grow and remodel themselves to adapt to
their surrounding mechanical environment through metabolic processes. By contrast,
typical synthetic materials cannot grow and reconstruct their structures once formed.
We present a strategy for developing “self-growing” polymeric materials that respond
to repetitive mechanical stress through an effective mechanochemical transduction in
the robust double network hydrogels [1]. We show that the double-network hydrogels,
with supply of monomers, self-grow and significantly strengthen under repetitive
loading. Such sustained self-growing is through a repetitive structural destruction and
reconstruction process, in analogy to the metabolic processes of biological system.
This strategy also endows to impart the hydrogels with tailored functions at desired
positions by mechanical stimuli. This work may pave the way for the development of
self-growing gel materials for applications such as soft robots and intelligent devices.
References:
1. Jian Ping Gong, Soft Matter, 6(12), 2583-2590(2010).
2. Takahiro Matsuda, Runa Kawakami, Ryo Namba, Tasuku Nakajima, Jian Ping
Gong, Science, 363(6426), 504-508 (2019).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
5
PL 5
Low-molecular Mass Compounds-based Gels and Gel Emulsions:
From Aerogels to High Performance Porous Monoliths
Yu Fang
(Key Laboratory of Applied Surface and Colloid Chemistry, School of Chemistry and Chemical
Engineering, Shaanxi Normal University, Xi’an 710119, China)
*E-mail: [email protected]
Compared to conventional chemical and polymers-based physical gels, molecular gels
based on low-molecular mass compounds are more sensitive to external stimuli,
demonstrating reversible flowability change and phase transition. It is the property that
makes molecular gels acquire a variety of important applications. In this talk, I will focus
on extension of molecular gel studies to gel-emulsions and the relevant template
preparation of porous polystyrene monoliths. As will be presented, the volume fraction of
the dispersed phase in the new concept gel-emulsions could be much lower than the
well-known limit of 74% of conventional ones. A possible reason behind is the using of
low-molecular mass gelators as stabilizers, which gels the continuous phase. In other
words, gel-emulsions have changed from conventional bis-liquid to liquid-gel systems,
implying that the systems lost their flowability not because of dispersed phase crowding,
but because of physical trapping. As will be demonstrated through case studies, remove
of the restriction has largely extended the application of gel-emulsions in template
preparation, allowing creation of porous materials from light-weight aerogels to
low-density high strength monoliths. Recent progress in the studies of other gel-related
dynamic systems may be also presented provided time is allowed.
Keywords: Molecular gels, Gel-emulsions, Template preparation, Porous monoliths
References:
Adv. Mater. 2019, 31, 1808254; Macromolecules 2019, 52, 2456-2463; Soft Matter 2018, 14,
7950-7953; Macromol. Rapid Commun. 2018, 39, 1700679; Chem. Eng. J. 2018, 339, 14-21; J.
Mater. Chem. C, 2018, 6, 12493-12497; Chem. Mater. 2017, 29, 5957-5964; Langmuir 2017, 33,
10419-10428 (Invited Feature Article); Macromol. Rapid Commun. 2017, 38, 1700270- 1700274;
Mol. Syst. Des. Eng. 2016, 1, 242-257; ACS Appl. Mater. Interfaces 2016, 8, 18584-18592; J.
Mater. Chem. A 2015, 3, 24322-24332; ACS Appl. Mater. Interfaces 2015, 7, 10718-10726; Soft
Matter 2014, 10, 9159-9166; Langmuir 2014, 30, 13680-13688; J. Mater. Chem. A2014, 2,
10081-10089; Chem. Commun.2014, 50, 13940-13943; J. Am. Chem. Soc. 2013, 135, 8989-8999;
Soft Matter2013, 9, 1091-1099; Soft Matter2013, 9, 5807-5814; Langmuir2013, 29, 793−805; J.
Mater. Chem. A2013, 1, 10135-10141
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
6
PL 6
Photo-reactive polymers for medical applications
Yoshihiro Ito 1,2
(1Nano Medical Engineering Laboratory, RIKEN Cluster for Pioneering Research, 2-1
Hirosawa, Wako-shi, Saitama 351-0198, Japan; 2Emergent Bioengineering Materials Research
Team, RIKEN Center for Emergent Matter, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan)
*E-mail: [email protected]
We have been developed two types of photo-reactive polymers for medical
applications. One is visible-light cross-linkable biological polymers. Another is
UV-curable polymers.
The visible-light reactive polymers consisted of gelatin, alginate, and chitosan
and they were prepared by coupling with furan group. In the presence of non-toxic
photosensitizers such as Rose Bengal and riboflavin, the conjugated furan produced
oxides by visible-light irradiation and reacted with others. They have been applied as
scaffolds for tissue engineering or bioadhesives.
Another UV-reactive polymer was prepared by coupling with azidophenyl group.
Gelatin was coupled with the photo-reactive group and the conjugate was used for
micropattern-immobilization of growth factors. The micropatterning was useful to
investigate the effect of immobilized growth factor. Another utilization is for
microarray immobilization with non-biofouling polymers. The photo-immobilization
is all-round one because immobilization mechanism is based on radical reactions The
immobilized microarray has been used for multiple detection of bio-markers.
Keywords: Photo-reactive, Cross-linking, Medical Adhesive, Immobilization
References:
[1]. Yoshihiro Ito, ed. “Photochemistry for Biomedical Applications”,
Springer-Nature (2018)
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
7
PL 7
Mechanical stability of fiber networks
Miklos Zrinyi, Evelin Sipos, Akos Juhasz
Laboratory of Nanochemistry, Department of Biophysics and Radiation Biology,
Semmelweis University, H-1089, Nagyvárad tér 4. Hungary
Email: [email protected]
Fibrous materials have important technological applications owing to their
excellent mechanical performance and low weight. The mechanical properties of fibre
assemblies depends on the strength and the toughness of single fibres as well as on
their geometrical arrangement. The mechanical behavior of fibrous materials deviates
significantly from that of traditional materials because of the discontinuous nature of
randomly distributed fibres. Despite their high strength, little information is available
about the deformation mechanism of spun fabrics; the load bearing capacity of these
materials critically affects many technological and biomedical applications.
This work presents the results of unidirectional strain-controlled experiments on
fibrous electrospun networks used to study damage formation during elongation. The
experimental loading curve shows a symmetrical parabolic type dependence at large
scale and saw tooth-like forceextension behaviour at small scale. The damage
formation was quantified by determining the number and the magnitude of abrupt
force drops. The experiments evidenced that damage evolution is a consequence of
strain induced random events. The frequency distribution of the number of damages
as well as the magnitude of rupture force were experimentally studied and compared
with computer simulation. The results provide a better insight into damage tolerance
and complex nonlinear tensile properties of electrospun networks.
Keywords: Fiber networks, Fiber Bundle Model, Electrospinning, Damage formation
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
8
IL1-1
Polyampholyte Hydrogels with pH Modulated Shape Memory and
Spontaneous Actuation*
Yuancheng Zhang, Jiexin Liao, Tao Wang*, Weixiang Sun, Zhen Tong*
(Research Institute of Materials Science, South China University of Technology
Guangzhou 510640, China)
E-mail: [email protected]
Generally, the temporary shape of shape memory polymers is formed by an
external force and fixed by some reversible interactions, which are triggered at the
conditions gentler than that maintaining the permanent shape. For the hydrogels,
the special circumstance is that plenty of water inside promotes the polymer chain
motion and weakens the temporary shape fixation. On the other hand, all of the
actuations are one-off, and the original shape cannot convert to the temporary shape
spontaneously and reversibly. For reversible alternation between the original and
temporary shapes, the hydrogels are usually fabricated with anisotropic structures to
transfer the isotropic volume expansion into anisotropic movements. However,
these usually require complicated preparation or/and external control devices. The
spontaneous shape change from the original to temporary is essential for a continuous
actuation.
We synthesized polyampholyte hydrogels consisting of strong cationic
monomer with both strong and weak anionic monomers without chemical crosslinker
and adding salts. The hydrogels exhibited pH responsive shape memory: the
temporary shape was formed manually after immersing in NaOH solution and fixed in
HCl solution, while the shape recovery occured by immersing in NaOH again.
Most interestingly, the hydrogel showed a spontaneous shape change after the first
shape memory cycle. When the recovered hydrogel with a little residual
deformation was immersed in HCl again, it twisted spontaneously and rapidly to the
previous temporary shape. The spontaneous twisting and recovering can be
repeated for 10 times by alternately immersing in NaOH and HCl solutions without
any external force. Furthermore, the hydrogel swelled quickly and was
strengthened in HCl, while shrank and weakened in NaOH during the shape change
procedure. This unique synergistic effect of fast swelling, residual helical
deformation, and increased strength played a significant role to the spontaneous shape
alternation.
Keywords: Polyampholyte hydrogels, Spontaneous actuation, Shape memory
* This research was supported by the NNSFC (21427805).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
9
IL1-2
Hydrogels with ultra-dynamic network enhance
mechanosensing-dependent activities of encapsulated stem cells
Liming Bian1†, Boguang Yang1, Kongchang Wei1
(1 Department of Biomedical Engineering, Chinese University of Hong Kong, Hong Kong,
China)
*E-mail: [email protected]
In living organisms, cells are constantly interacting with and remodeling the highly dynamic
extracellular matrix (ECM), and this process enables various cell behaviors including
proliferation, migration, and differentiation[1]. The dynamic properties of the natural ECM
primarily stem from two orthogonal sources, the enzymatic degradation of biopolymers and the
force-induced dissociation/re-association of physical crosslinks in the biopolymer network.
The latter typically operates at a significantly shorter timescale and higher frequency than the
former, thereby giving rise to the temporal hierarchy of ECM dynamic behaviors. However, the
natural ECM is highly complex, and precisely manipulating its dynamic properties remains
difficult. Therefore, designing a three-dimensional (3D) polymeric matrix with tunable
dynamic properties to recapitulate this temporal hierarchy of ECM dynamics is of great
importance for decoupling the effects of 3D matrix dynamics on cell behaviors. Our
supramolecular hydrogels (HGHA) crosslinked by engineered multivalent host-guest
complexations possess ultra-high network dynamics as revealed by relaxation spectra and
dynamic rheological analysis. Our data showed that HGHA hydrogels with decorated RGD
peptides supported ultra-rapid (within 18 h post encapsulation) stellate spreading of the
encapsulated hMSCs. The ultra-rapid cell spreading was supported by the formation of a cell
adhesion structure rich in β1 class integrins and led to enhanced activation of mechanosensing
factors, including FAK phosphorylation and YAP nuclear translocation. Consequently,
compared with control hydrogels with less dynamic structures, the HGHA hydrogels
significantly enhanced mechanotransduction-dependent hMSC osteogenic differentiation.
Keywords: hydrogels, stem cells, 3D culture, mechanotransduction
References:
[1] O. Chaudhuri, L. Gu, D. Klumpers, M. Darnell, S.A. Bencherif, J.C. Weaver, N. Huebsch, H.P. Lee,
E. Lippens, G.N. Duda, D.J. Mooney, Hydrogels with tunable stress relaxation regulate stem cell fate
and activity, Nat Mater 15(3) (2016) 326-34.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
10
IL1-3
Mussel inspired cell/tissue adhesive hydrogels with multi-functions
Xiong LU (鲁雄)
Presenting Author, Authors (Time New Roman, 12 point)
Key Lab of Advanced Technologies of Materials, Ministry of Education, School of
Materials Science and Engineering, Southwest Jiaotong University,
Chengdu 610031, Sichuan, China
西南交通大学材料科学与工程学院,材料先进技术教育部重点实验,四川成都 610031)
*E-mail: [email protected]
Hydrogels are attractive biomaterials owing to their high water content and structural
resemblance to natural soft tissue. Intense efforts have been devoted to synthesizing hydrogels
for soft tissue repair, which requires not only toughness, but also cell affinity, tissue
adhesiveness, and self-healing ability. However, the commonly reported tough hydrogels lack
cell affinity and tissue adhesiveness, and therefore can not fully meet requirements of the
practical applications. Recently, mussel-inspired chemistry sheds new light on the
development of hydrogels with good cell affinity and tissue adhesiveness.
In this study, we report a series of mussel inspired hydrogel that simultaneously possess
those properties by incorporating various nanocomponents in the hydrogels, such as graphene,
CNT and nano clay. The hydrogel have super stretchability and high toughness. In addition,
the hydrogel has metal-free the self-healing ability, which can self-heal under the ambient
environment without other external stimuli. The hydrogels also possess good affinity to cells
and high adhesiveness to tissues, which can induce skin tissue regeneration for repairing full
skin defect. The tough hydrogel with cell affinity, tissue adhesiveness, and self-healing is an
excellent candidate for repairing the damaged tissue that withstands fatigue under cyclic
loading. In summary, the hydrogel could serve as a universal platform to incorporate many
types of functional NPs, resulting in hydrogel with multiple functionalities, such as magnetic
and conductive response properties. It might have broad applications in tissue engineering,
such as load-bearing cartilage, tendon and artificial skin. This development of this hydrogel is
a giant step forward for the practical applications of tough hydrogels
Keywords: mussel inspired, hydrogel, adhesive, tough
References:
[1] Lu Han, Xiong Lu*, et al , Adv. Funct. Mater. 2018, 28 (3) 1704195,
[2] Donglin Gan, Xiong Lu*, et al Adv. Funct. Mater. 2019, 29, 1805964
[3] Donglin Gan, Xiong Lu*, et al Nature Communications 2019
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
11
IL1-4
Underwater Microphones: Electric Double Layers at the
Electrode-Gel Interface
Meixiang Wang1, Xuejing Shen2,3, Xueqi Zhao1, Shichao Li2,3, Michael Sealy3,
Zhanjun Wu2, Yongmei Chen1,4*, Qin Zhou3*, and Li Tan3*
1Xi’an Jiaotong University; 2Da’lian University of Technology; 3University of
Nebraska-Lincoln; and 4Shaan’xi University of Science and Technology.
Electrically when a block of hydrogel is brought into contract with an electrode, an
electric double layer (EDL) forms at their interface. One unique property of EDL is
its large capacitance, which provides the foundation for supercapacitors. If the
capacitance can somehow be tuned by external mechanical stimuli such as acoustic
waves, an extremely sensitive transducer can be made. We show that the
transduction mechanism can either be introduced by the implantation of silver
nanotrees or by placing a block of hydrogel next to a single-atom-thick graphene.
Both approaches, however, involve electrochemical reactions at the gel-electrode
interface. We reveal that a simple replacement of hydrogel with ionic liquid gel is
not effective; rather, a deep understanding of EDL will pave the way, ultimately
resulting in much improved sensor lifetime and signal-to-noise ratio for those
underwater microphones.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
12
IL1-5
Bioinspired nucleobase-driven adhesive hydrogels with excellent
underwater adhesion
Guang Hui Gao‡, Xin Liu, Qin Zhang
(Polymeric and Soft Materials Laboratory, School of Chemical Engineering and Advanced
Institute of Materials Science, Changchun University of Technology, No. 2055, Yan'an Street,
Changchun, P. R. China)
*E-mail: [email protected]
Bio-inspired strategies for designing hydrogels with excellent adhesive
performance have drawn much attention in biomedical applications. In our works,
bioinspired adhesive hydrogels tackified by independent nucleobase (Adenine,
Thymine, Guanine, Cytosine and Uracil) from DNA and RNA are successfully
explored. The nucleobase-tackified hydrogels exhibit an excellent adhesive behavior
for not only various solid substrates (polytetrafluoroethylene, plastics, rubbers, glasses,
metals and woods), but also biological tissues consisting of heart, liver, spleen, lung,
kidney, bone and muscle. However, it is still demanding to construct a tough
underwater gel-based adhesive completely based on the chemical constitution.
Inspired by the underwater adhesion mechanism of marine organism, the underwater
adhesive behavior is skillfully regulated through hydrophobic aggregation induced by
solvent exchange. The adhesive gels exhibit an excellent adhesive behavior for
various materials in the air and various aqueous solutions, including deionized water,
seawater, acid and alkali solutions (pH=3 and 10). It is anticipated that the bioinspired
nucleobase-tackified strategy would open a novel avenue for designing the next
generation of soft and adhesive materials.
Keywords: Hydrogels, Nucleobase, Underwater adhesion
References:
[1] Liu X; Zhang Q; Gao G*, Adv. Funct. Mater. 2017, 27, 1703132.
[2] Liu X; Zhang Q; Duan L; Gao G*, Adv. Funct. Mater. 2019, 1900450.
[3] Liu X; Zhang Q; Duan L; Gao G*, ACS Appl. Mater. Interfaces, 2019, 11, 6644.
This research was supported by the National Natural Science Foundation of China (Grant No.
51873024 and 51703012).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
13
IL1-6
Mechanical reinforcement of soft matter: design of synthetic gels as
model systems
Alba Marcellan1,2
(1Soft Matter Sciences and Engineering, ESPCI Paris, PSL University, Sorbonne University,
CNRS, F-75005 Paris, France ; 2Global Institution for Collaborative Research and Education,
Global Station for Soft Matter, Hokkaido University, Sapporo, Japan)
E-mail: [email protected]
By using concepts of polymer physics, we developed some strategies1-2 to design
tough “hybrid” gels that combine covalent (permanent) cross-links and physical
(reversible) sacrificial interactions. Recently, a novel mode of fracture toughening by
crack bifurcation has been highlighted in phase-separated hydrogels3-4. We designed
original gel topologies that phase-separate at constant macroscopic volume and quite
high level of hydration, independently of the phase-separation process. The polymer
network combines a conventional network with thermo-responsive domains which act
as reinforcing fibers operating at a targeted temperature. Network topology is crucial
to enhance efficiently the fracture resistance of the gels.
Figure. Impact of gel topology on fracture properties, from Ref. [3].
PNIPAm and PDMA are pictured in red and blue, respectively.
Keywords: Phase-separated Gels, Self-recovery, Fracture toughening
References:
[1]. Rose, Dizeux, Narita, Hourdet, Marcellan*, Macromol. 2013, 46, 4095
[2]. Rose, Prevoteau, Elziere, Hourdet, Marcellan, Leibler, Nature 2014, 505, 382
[3]. Guo, Sanson, Hourdet, Marcellan, Adv. Mater. 2016, 28, 5857
[4]. Guo, Mussault, Brulet, Marcellan, Hourdet, Sanson, Macromol. 2016, 49, 4295
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
14
IL1-7
Bioinspired Chiral Supramolecular Hydrogels
Chuanliang Feng§, Xiaoqiu Dou, Jinying Liu
State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, 800
Dongchuan Road, Shanghai 200240, China.
E-mail: [email protected]
Chirality is one of life’s most distinctive biochemical signatures and has great
influence on many biological events. So far, the researches are mainly confined to the
role of molecular chirality on two dimensional (2D) surface and a lot of questions
remaining to be answered. Among them, how nanofibrous chirality influences cell
behaviors in three dimensional (3D) extracellular matrix (ECM) is especially
important, since it is only the 3D ECM nanofibrous structure can really mimick the
necessary biophysical environment for tissue engineering and helical nanofibrous
structure is closely related with relevant biological events. To overcome this issue, the
candidate has proposed a novel material design of constructing sandwich-like chiral
molecular structure that can achieve chiral transformation from molecular level to
macroscopic level, leading to the formation of highly ordered self-assembled hydrogel
biomaterials with helical chiral features. Moreover, it was revealed that left-handed
hydrogel can promote cell adhesion and proliferation. Based on these results, an
antibacterial ointment that can cure skin ulcer caused by diabetes has been developed.
This research paves innovative ways to develop new generation of biomaterials in the
fields of tissue engineering and biomedicine.
Keywords: Gelators, Hydrogels, chirality, self-assembly, cells
References:
[1] Liu J; Yuan F; Ma X; Auphedeous D; Zhao CL; Liu CT; Shen CY; Feng CL,*
Angew. Chem. Int. Ed., 2018, 57, 6475-6479.
[2] Wang F; Feng CL,* Angew. Chem. Int. Ed., 2018, 57, 5655-5659.
[3] Choi H; Cho K; Seo H; Ahn J; Liu J; Lee SS; Kim H;* Feng CL;* JungJH*, J. Am.
Chem. Soc. 2017, 139, 17711-17714
[4] Dou XQ; Feng CL,* Adv. Mater. 2017, 29, 604062.
This research was supported by the National Natural Science Foundation of China (Grant No.
51833006, 51573092).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
15
IL1-8
Multifunctional hydrogels for rapid hemostasis and tissue repair
Baolin Guo**
(Frontier Institute of Science and Technology, Xi’an Jiaotong University, Xi’an 710049, China)
*E-mail: [email protected]
Uncontrolled bleeding results in more than 30% of traumatic deaths. Although currently used
hemostatic agents exhibit excellent performance in hemostasis of limb surface wounds, they
generally have a poor hemostatic effect on deep wound bleeding. We prepared chitosan
derivatives and carbon nanotube materials to form injectable shape memory nanocomposite
porous gelatin hemostatic materials. Chitosan derivatives can provide good hemostatic
properties, promote wound healing and blood-triggered shape memory recovery. Due to the
rapid blood absorption, blood concentration and rapid blood-triggered shape recovery of the
composite gel, as a physical filling barrier with sufficient mechanical properties, it exhibits
excellent performance in rabbit liver volume loss and incompressible hemorrhage death
model.
After the bleeding stops, the severe skin defect of the skin is a serious threat to people's health
and life. At present, most of the injectable gel dressings have only a single biological activity,
which limits their multiple promoting effects on wound healing. We have reported an
injectable hydrogel dressing that has both self-healing and high adhesion. The in-situ gelation
and tissue adhesion properties of the hydrogel can quickly seal any shape of the wound to
provide a physical barrier, while the hemostatic and antibacterial properties of the gel can
allow the wound to stop bleeding quickly and prevent wound infection. Thus, the hydrogel
has great potential as a bioactive dressing in wound healing applications.
Keywords: Hemostasis; skin repair; muscle repair; conductive biomaterials; hydrogel
References: [1] X Zhao, B Guo*, H Wu, Y Liang, PX Ma*, Nature Communications, 2018, 9:
2784. [2] Y Wu, L Wang, B Guo*, PX Ma, ACS Nano, 2017, 11 (6), 5646-5659. [3] L Wang, Y
Wu, B Guo*, PX Ma, ACS Nano, 2015, 9 (9), 9167-9179. [4] J Qu, X Zhao, Y Liang, T Zhang,
PX Ma, B Guo*, Biomaterials, 2018, 183, 185-199. [5] X Zhao, H Wu, B Guo*, R Dong, Y Qiu,
PX Ma, Biomaterials, 2017, 122, 34-47. [6] Y Wu, L Wang, B Guo*, Y Shao, PX Ma,
Biomaterials, 2016, 87, 18-31.
This research was supported by the National Natural Science Foundation of China (Grant No.
51673155).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
16
IL2-1
Highly Plasticized PVC Gel with Smart Functions Electrical, Optical,
Mechanical -
Toshihiro HIRAI††
(Fiber Innovation Incubator, Faculty of Textile Science and Technology, Shinshu University,
Tokida 3-15-1, Ueda 386-8567, Japan.)
*E-mail: [email protected]
Highly plasticized poly(vinyl chloride) (PVC)-gels have brilliant performance as
electroactive gels. The plasticizers are commercially conventional ones with fairy low
specific dielectric constant (usually <10). The gels showed very small d3 strain as
expected, but huge “creeping deformation” to anode surface. The strain is only on
anode surface, but not on cathode surface. The gel exhibited colossal dielectric
constant (>103) at low frequency range less than kHz. The space charge distribution in
the gel shows totally asymmetric feature. On anode side, negative charge
accumulation is observed, but no positive charge on cathode side. The space charge
generated strong tacking force to anode and the repulsion among the charge leads the
expansion on anode, thus we can observe “amoeba-like” pseudopodial deformation of
the gel. This deformation can successfully be applied for “contractile artificial
muscle” which can pull up 80kg/10cm2 and durable over 5x106 times operation.
Furthermore, the gel exhibits electro-optical function such as Kerr effect over 30
times larger than that of nitrobenzene. Haptic sensor function will also be introduced
in the presentation.
Keywords: PVC, Gel, Dielectric, Electro-mechanical, Electro-optical,
Artificial-muscle, Piezo-function
References:
[1]. Wei Z.; Yang JH.; Liu ZQ.; Xu F.; Zhou JX.; Zrínyi M.; Osada Y.; Chen YM* ,
Adv. Funct. Mater. 2015, 25,1352 [1]. Hirai T.: Xia H: Chap.1, Handbook
This research was supported by the National Natural Science Foundation of China (Grant No.
11674263).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
17
IL2-2
High Frequency dynamics of polymer solutions and gels studied by
microrheology
Tetsuharu Narita1,2
(1Laboratory of Soft Matter Science and Engineering, ESPCI Paris – CNRS – Sorbonne
Université, Paris, France; 2Global Station for Soft Matter, Global Institution for Collaborative
Research and Education, Hokkaido University, Sapporo, Japan)
*E-mail: [email protected]
The dynamics of soft matters spread across several orders of magnitude on the
time, reflecting the various relaxation processes at different length scales. For the case
of polymer solutions and gels, single chains and clusters of chains have specific
structures and corresponding dynamics, exhibiting characteristic scaling regimes of
viscoelastic moduli at a high frequency range (typically at 103 – 106 rad/s), while it is
not easy to access to these frequencies by conventional rotational shear rheometers.
We work on passive microrheology by dynamic light scattering techniques
(single dynamic light scattering, DLS, and multiple dynamic light scattering called
diffusing-wave spectroscopy, DWS) which allow us to access to the high frequency
range. From the dynamic light scattering signals coming from probe particles
dispersed in viscoelastic media, the mean square displacement of the particles due to
the thermal energy is measured. By using the generalized Stokes-Einstein relation one
can calculate high frequency viscoelastic moduli of the media. In this talk I will
briefly explain the experimental details of microrheology, then I will show some
examples of high frequency dynamics of polymer aqueous solutions and hydrogels:
(1) Single chain rigidity: Single chain rigidity can be characterized by its bending
mode found at high frequencies. By using solutions of a giant polysaccharide “sacran”
as model system, the bending mode was microrheologically studied. The
concentration dependence of the persistence length was discussed.
(2) Percolation of chains by transient crosslinks: A polymer network transiently
crosslinked by reversible associations flows at low frequency. Its gel point was
microrheologically determined by observing a high frequency power-law behavior
corresponding to the rheological response of a self-similar network at the percolation
point.
Keywords: microrheology, sol-gel transition, persistence length
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
18
IL4-1
Anisotropic composite gels from liquid crystalline nanosheets
Nobuyoshi Miyamoto‡‡
, Takumi Inadomi, Wenqi Yang
(Department of Life, Environment and Materials Chemistry, Graduate School of Engineering,
Fukuoka Institute of Technology, 3-30-1, Wajiro-Higashi, Higashi-ku, Fukuoka 811-0295, Japan)
*E-mail: [email protected]
Lyotropic liquid crystals (LCs) of inorganic nanosheets1) are emerging as
new-type LC materials with rich electric and optical functionalities inherent to
inorganic materials. Here we demonstrate the synthesis of composite hydrogels with
anisotropic properties by utilizing inorganic nanosheet LCs.2) The gels were
synthesized by photo-polymerization of N-isopropylacrylamide (NIPA) dissolved in
the liquid crystalline fluorohectorite clay colloid; electric field was applied during the
polymerization to achieve macroscopic alignment of the LC domains. The obtained
gels showed anisotropic properties such as optical birefringence and anisotropic
elastic moduli. The gels also show anisotropic molecular diffusion due to blocking of
diffusion by the aligned nanosheets. When self-oscillating BZ-reaction proceeds in
the gel, the patterns generated by the chemical wave propagation is concentric
ellipsoids, different form normal concentric circles, due to different diffusion rate of
the molecules along two axes. Further, the gel is printable with μm-scale resolution
with cationic dyes because the dye is strongly adsorbed electrostatically on the
anionic nanosheets. When the gel is irradiated with light, only the colored part is
photothermally deformed anisotropically, which is suitable for applications as soft
actuators.
Keywords: Inorganic nanosheets, Liquid crystal, Composite gel, Anisotropy
References:
[1] Miyamoto, N.; Nakato, T., Adv. Mater. 2002, 14 (18), 1267-1270.
[2] Miyamoto, N.; Shintate, M.; Ikeda, S.; Hoshida, Y.; Yamauchi, Y.; Motokawa, R.;
Annaka, M., Chem. Commun. 2013, 49, 1082-1084; Inadomi, T.; Ikeda, S.; Okumura,
Y.; Kikuchi, H.; Miyamoto, N., Macromol. Rapid Commun. 2014, 35, 1741-1746.
[4] Shintate, M.; Inadomi, T.; Yamamoto, S.; Kuboyama, Y.; Ohsedo, Y.; Arimura, T.;
Nakazumi, T.; Hara, Y.; Miyamoto, N., J. Phys. Chem. B 2018, 122, 2957–2961.
This research was supported by Strategic Research Foundation Grant-Aided Project for Private
University (#S1511036L) from MEXT and KAKENHI (#24104005 and #15K05657).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
19
IL4-2
Biomimetic shape-transformation of composite hydrogel films
Zhihong Nie1§§, Teng Li2
(1State Key Laboratory of Molecular Engineering of Polymers,Department of Macromolecular
Science,Fudan University, 2005 Songhu Rd, Shanghai 200438, China; 2Department of Mechanical
Engineering,University of Maryland, College Park.)
*E-mail: [email protected]
Adaptable materials have been designed to respond to a particular, well-defined
external stimulus such as heat, light, or the variation in humidity, acidity and ionic
strength of the surrounding medium. Multiplexing system’s functionality is an
appealing concept that enables the design of materials with multiple, distinct
properties, each of which is activated by a particular external trigger[1]. In this talk, I
will present our efforts on achieving multiple 3D shape transformations of planar gel
sheets in response to distinct external triggers (e.g., pH, light, etc.)[2-6]. For instance,
we developed a composite macroporous hydrogel sheet that can rapidly transform into
multiple 3D shapes in response to near-infrared (NIR) light on demand. The
transformation relies on the photo-thermal-induced asymmetric shrinking of the
hydrogel material, which is further verified by finite element modeling.
Keywords: Hydrogel, Shapes, Deformation, Responsive, Films
References:
[1] Kempaiah, R.; Nie, Z. H. Journal of Materials Chemistry B 2014, 2, 2357-2368.
[2] Therien-Aubin, H.; Wu, Z. L.; Nie, Z. H.; Kumacheva, E. Journal of the American
Chemical Society 2013, 135, 4834-4839.
[3] Wu, Z. L.; Moshe, M.; Greener, J.; Therien-Aubin, H.; Nie, Z. H.; Sharon, E.;
Kumacheva, E. Nature Communications 2013, 4.
[4] Guo, H. Y.; Cheng, J.; Wang, J. Y.; Huang, P.; Liu, Y. J.; Jia, Z.; Chen, X. Y.;
Sui, K. Y.; Li, T.; Nie, Z. H. Journal of Materials Chemistry B 2017, 5, 2883-2887.
[5] Wei, Z. J.; Jia, Z.; Athas, J. M.; Wang, C. Y.; Raghavan, S. R.; Li, T.; Nie, Z. H.
Soft Matter 2014, 10, 8157-8162.
[6] Fan, W.X.; Shan, C.Y.; Guo, H.Y.; Sang, J.W.; Wang, R.; Zheng, R.R.; Tan,
Y.Q.; Sui, K.Y.; Nie, Z.H. Sci. Adv., 2019, 5(4), eaav7174.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
20
IL 4-3
Active Gap Control of Gold Nanodots using Gels in Nanoscale
Hideyuki Mitomo1,2*, Satoshi Hamajima3, Kuniharu Ijiro1,2
(1 RIES, 2 GI-CoRE, 3Grad. Sch. of Chem. Sci. and Eng.,Hokkaido Univ., Sapporo 001-0021,
Japan)
*E-mail:[email protected]
Gold nanostructures are of considerable interest as their plasmonic phenomena
can provide functional applications. One of typical examples is a surface-enhanced
Raman scattering (SERS), which is a promising way for the label-free detections of
materials. On this SERS application, gap structures and their distances of metal
nanostructures are crucially important. A narrower gap can basically provide more
enhanced signals, but it also makes the insertion of analytes into the hot spots more
difficult owing to the steric hindrance. In our previous study, we had developed the
fabrication method for metal nanoarrays on the the hydrogel surface and investigated
whether active gap control by the gel volume change affected on SERS measurements
[1, 2]. As a results, we found this active gap control technique could provide further
enhanced SERS signals. However, it remains unclear how accurately controlled the
gap distance changes are. Therefore, in this study, we evaluated each gap distance on
the gels at various swelling conditions by scanning electron microscope observation.
Our results showed their gap changes are quite homogenous in nanometer scale,
although various ranges of inhomogeneities on the gel network were reported. Our
results suggested that active gap tuning using gels are quite useful [3].
Keywords: Gel, Gold nanostructures, Active Control, Surface Plasmon Resonance,
References:
[1] N. Shimamoto, Y. Tanaka, H. Mitomo, R. Kawamura, K. Ijiro, K. Sasaki, Y.
Osada*, Adv. Mater. 2012, 24, 5243.
[2] H. Mitomo, K. Horie, Y. Matsuo, K. Niikura, T. Tani, M. Naya, K. Ijiro*, Adv.
Opt. Mater., 2016, 4, 259.
[3] S. Hamajima, H. Mitomo*, T. Tani, Y. Matsuo, K. Niikura, M. Naya, K. Ijiro*,
Nanoscale Adv. 2019 (DOI: 10.1039/c8na00404h)
This research was supported by JSPS KAKENHI (Grant Number JP16K20870 and
JP18H01804).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
21
IL 4-4
Anomalous expansion of clusters in percolation process in diluted
system
Takamasa Sakai1
(1Department of Bioengineering, Graduate School of Engineering, The Uniersity of Tokyo,
7-3-1 Hongo Bunkyo-ku, Tokyo, Japan)
*E-mail: [email protected]
Percolation is a process during which clusters grow and fill the system. In this paper,
we propose a new mechanism of percolation especially in a diluted system, which
predicts anomalous expansion of clusters during the agglomeration. We examined the
mechanism by investigating gelation processes of a diluted system by means of
experiments and molecular dynamics simulation. We confirmed that clusters grew
during the gelation, and a diluted system became a semi-diluted system just below the
gelation threshold. As a result, gels behaved as semi-diluted system regardless of the
initial polymer concentration. These results suggest the similarity between the
gelation threshold and the overlapping condition. This anomalous expansion is a key
of off-lattice percolation problem, and will help better understand general off-lattice
percolation problems.
Keywords: Gel, Sol-gel transition, Tetra-PEG gels
References:
[1] Fujinaga I.; Asai M.; Chung U.; Sakai T.*, submitted.
–––––––––––––––––––––––––––––––––
This research was supported by the JSPS (Grant No. 18H02027 and 16746899).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
22
IL 5-1
Ion-to-Ion Amplification through an Open Junction 1 Ionic Diode
Jeong-Yun Sun
(Department of Materials Science & Engineering, Seoul National University, Seoul 08826,
Korea)
As biological signals are mainly based on ion transport, the differences in signal
carriers have become a major issue for the intimate communication between electrical
devices and biological areas. In this respect, an ionic device which can directly
interpret ionic signals from biological systems needs to be designed. Particularly, it is
also required to amplify the ionic signals for the effective signal processing since the
amount of ions acquired from biological systems is very small. In this study, we
report on the signal amplification in ionic systems as well as sensing through the
modified design of polyelectrolyte hydrogel based ionic diodes. By designing an open
junction structure, ionic signals from the external environment can be directly
transmitted to an ionic diode. Moreover, the minute ionic signals injected to the
devices and can also be amplified to a large amount of ions. The signal transduction
mechanism of the ion-to-ion amplification is suggested and clearly verified by
revealing the generation of breakdown ionic currents during an ion injection.
Subsequently, various methods for enhancing the amplification are suggested.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
23
IL5-2
Active network of motor proteins as artificial dynamic
microenvironment for cells
Ryuzo Kawamura1,2***, Keisuke Meguriya1, Tsuyoshi Yokoyama1, Daiki Uehara1,
Naritaka Kobayashi2, Seiichiro Nakabayashi1,2, Hiroshi Y. Yoshikawa1,2
(1Depoartment of Chemistry, Saitama University, Saitama 338-8570, Japan; 2Division of
Strategic Research and Development, Graduate School of Science and Engineering, Saitama
University, Saitama 338-8570, Japan.)
*E-mail: [email protected]
Dynamic network of cytoskeletal and motor proteins generates various
movements and allows cells to divide, to deform and to migrate with consumption of
chemical energy. It means that in vivo micromechanical environment of cell is
mechanically dynamic due to the movement of the surrounding cells, as the cell in the
tissues are surrounded by the other cells. There, the nanometric movements of the
motor proteins are integrated to micrometer or larger scales with/without order and it
can lead to mechanical fluctuations at cellular scale in the environment. However,
conventional technique to culture cells on a plastic dish has lacked such a dynamic
micromechanics. Inspired from the dynamic property of the cells, we have been
proposing a dynamic substrate which can give mechanical stimulation to the culturing
cells in a mesoscopic scale from nano- to micrometer [1]. With use of microtubule
and kinesins [2], dynamic network of microtubules on a kinesin-coated glass surface
was constructed in a live cell compatible environment. Seeding cells on this dynamic
substrate coupled with ATP hydrolysis, we found that the mechanically stimulated
cells showed different morphology compared to those without stimulations.
Keywords: Gel, Active material, Motor protein, Cell Adhesion, Cancer
References:
[1]. Kawamura R*.; Uehara D.; Kobayashi N.; Nakabayashi S.; Yoshikawa H.Y.,
ACS Biomater. Sci. Eng. 2016, 2,2333.
[2]. Kawamura R*.; Sano K.; Osada Y., “Soft Actuators – Materials, Modelling,
Applications, and Future Perspectives (2nd edition, Springer). Edited by Kinji Asaka
and Hidenori Okuzaki”, Chapter “Employing Cytoskeletal Treadmilling in
Bio-Actuators” (in press).
This research was supported by LEADER program MEXT Japan, Nikki-Saneyoshi (JGC-S)
research grant and Takeda research grant.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
24
IL5-3
Functional modification, Controllable Fabrication and Biomedical
Applications of natural polymer Hydrogel
Guang Yang*,, Lin Xiao, Lallepak Lamboni, Zhijun Shi
(Department of Biomedical Engineering, College of Life Science and Technology, Huazhong
University of Science and Technology, Wuhan 430074, PR China.)
*E-mail: [email protected]
Hydrogels prepared from natural polymers such as Bacterial cellulose (BC) and
Chitosan have been widely used in biomedical engineering, and functional electric
devices due to its outstanding properties in terms of super softness, surface porosity,
optical transparency, and biocompatibility. The objective of our project is to combine
the design and manufacture of nanomaterials with the functional modification,
nano\micro fabrication method to develop strategies to construct novel natural
polymer multifunctional hydrogel. In this research, we extended the application of
functional BC and Chitosan hydrogel in bioelectrical interface, biocompatible wound
healing materials, cell microcarriers, injectable drug delivery system, artificial
shape-memory blood vessels, hierarchical intervertebral disc and so on.
Keywords: bacterial cellulose, chitosan,
References:
[1] Yang J, Wang L, Zhang W, Sun Z, Li Y, Yang M, Zeng D, Peng B, Zheng W*,
Jiang X*, Yang G*. Small, 2018, 14(7), 1702582.
[2]Huang L, Xiao L, Poudel AJ, Li J, Zhou P, Gauthier M, Liu H*, Wu Z*, Yang G*.
Carbohydrate Polymers, 2018: 611-620.
[3]Li, Y., Tian, Y., Zheng, W., Feng, Y., Huang, R., Shao, J., Tang, R., Wang, P.,
Jia,Y., Zhang, J., Zheng, W., Yang, G., Jiang, X. Small, 2017, 13(27).
[4] Shi, Z., Gao, X., Ullah, M. W., Li, S., Wang, Q., Yang, G. Biomaterials, 2016,
40-54.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
25
IL5-4
Ultrastretchable Stress and Strain Sensors Based on Tough
Conductive Hydrogels
Jun Fu1†††, Zhenwu Wang1, Liufang Wang1
(1Polymers and Composites Division, Ningbo Institute of Materials Technology and Engineering,
Chinese Academy of Sciences,Ningbo 315201, China.)
*E-mail: [email protected]
Ultrastretchable conductive materials are promisng for electronic skin,
human-machine interfaces, human activity monitors, and wearable electronic devices.
Currently, most strain sensors are comprised of elastomer matrix with metal
particles/liquid, carbon materials, or conductive polymers. In addition to the
stretchability and toughness, adhesive conductive hydrogels with linear sensitivity to
stress and strain are needed to fabricate reliable and wearable sensors to the skin.
This talk introduces, ultrastretchable and tough hydrogels with electronic or ionic
conductivities. Ionically conductive hydrogels comprised of zwitterionic chains
interpenetrating freeze-thawed PVA network show adhesiveness to many substrates
including glass, steel, polymer, and skin.
Electronic conductive hydrogels comprised of interpenetrating network of
polyalinine and P(AAm-co-HEMA) hydrogel show very high stretchability and
toughness. The hydrogels show a linear dependence on and high sensitivity to subtle
tensile strains (gauge factor 11).
The ultrastretchable and conductive hydrogels have been used to monitor subtle
movements of joints and wrist pusle, which suggest important applications in
implantable and wearable devices.
Keywords: Gel, Self-recovery, Conductivity, Sensor, Toughness, Stretchability
References:
[1]. Liufang Wang, Guorong Gao, Yang Zhou, Ting Xu, Jing Chen, Rong Wang, Rui
Zhang*, and Jun Fu*, ACS Applied Materials & Interfaces 2019, 11, 3506-3515.
[2]. Zhenwu Wang, Jing Chen, Yang Cong, Hua Zhang, Ting Xu, Lei Nie, Jun Fu*,
Chemistry of Materials 2018, 30, 8062-8069.
This research was supported by the National Natural Science Foundation of China (Grant No.
51873224).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
26
IL5-5
Instabilities in soft materials: from gels to metamaterials
Jinxiong Zhou
State Key Laboratory for Strength and Vibration of Mechanical Structures, School of Aerospace,
Xi’an Jiaotong University, Xi’an 710049, China
Soft materials have low moduli, and are venerable to a variety of instabilities in
response to environmental stimuli. Understanding these instabilities are crucial for
design, control and fabrication of soft materials based devices and machines. In this
talk, I will summarize our recent efforts towards modeling and understanding of
instabilities in soft materials. The topics range from polymer gels, liquid crystal
elastomers and then the emerged soft mechanical metamaterials. Finally, conclusions
and perspectives regarding this topic are also given.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
27
IL5-6
Stimuli-Responsive Smart Membranes
Liang-Yin Chu*
(School of Chemical Engineering, Sichuan University, Chengdu, Sichuan 610065, China.) *E-mail: [email protected]
Membranes are playing paramount roles for sustainable development in myriad
aspects such as energy, environments, resources and human health. However, the
unalterable pore size and surface property of traditional porous membranes restrict
their efficient applications. The performances of traditional membranes will be
weakened upon the unavoidable membrane fouling, and they cannot be applied to the
cases where self-regulated permeability and selectivity are required. Inspired by the
natural cell membranes with stimuli-responsive channels, artificial stimuli-responsive
smart membranes are developed by chemically/physically incorporating
stimuli-responsive materials as functional gates into traditional porous membranes to
provide advanced functions and enhanced performances for breaking the bottlenecks
of traditional membrane technology. The smart membranes, integrating the
advantages of traditional porous membrane substrates and smart functional gates, can
self-regulate their permeability and selectivity via flexible adjustment of pore sizes
and surface properties based on the "open/close" switch of the smart gates in response
to environmental stimuli.[1-3] This presentation introduces the recent development of
stimuli-responsive smart membranes, including the design strategies and the
fabrication strategies that based on introduction of the stimuli-responsive gates after
or during membrane formation, the positively and negatively responsive gating
models of versatile stimuli-responsive smart membranes, as well as the advanced
applications of smart membranes for regulating substance concentration in reactors,
controlling release rate of drugs, separating actives based on size or affinity, and
self-cleaning of membrane surfaces. With self-regulated membrane performances,
the smart membranes show great power for global sustainable development.
References:
[1] L.Y. Chu, Smart Membrane Materials and Systems, Springer-Verlag, Berlin (2011).
[2] Z. Liu, W. Wang, R. Xie, X.J. Ju, L.Y. Chu, Chem. Soc. Rev., 45, 460-475 (2016).
[3] L.Y. Chu, Smart Membranes, Royal Society of Chemistry, UK (2019).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
28
IL5-7
Construction of molecular swarm robot integrating
biomolecular soft actuators and processors
Akira Kakugo1,2‡‡‡, Jakia Jannat Keya1, Akinori Kuzuya3
(1Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan; 2Graduate School of
Chemical Sciences and Engineering, Hokkaido University, Sapporo 060-0810, Japan; 3Department
of Chemistry and Materials Engineering, Kansai University, Osaka 564-8680, Japan)
*E-mail: [email protected]
In nature swarming behavior evolves repeatedly among motile organisms
offering a variety of beneficial emergent properties. Switching between solitary and
swarm behavior can include improved information gathering, protection from
predators, and resource utilization. Inspired by the aspects of swarming behavior,
attempts have been made to construct swarm robots from motile supramolecular
systems composed of biomolecular motor system where cross-linkers induce large
scale organization. Here, we demonstrate that the swarming of DNA-functionalized
microtubules (MTs) propelled by surface-adhered kinesin motors can be programmed
and reversibly regulated by DNA signals. Emergent swarm behavior, such as
translational and circular motion, can be selected by tuning the MT stiffness.
Photoresponsive DNA containing azobenzene groups enables switching of swarm
behavior in response to stimulation with visible or ultraviolet light. Such control of
swarming offers design and development of molecular swarm robots based on natural
molecular devices.
Keywords: Swarming, Biomolecular motors system, DNA, swarm robot.
References:
[1]. Keya JJ.; Suzuki R.; Kabir AMR.; Inoue D.; Asanuma H.; Kazuki S.; Hess H.;
Kuzuya A.,* Kakugo A* Nat. Commun. 2018, 9:453
[2]. Keya JJ.; Kabir AMR.; Inoue D.; Kazuki S.; Hess H.; Kuzuya A.,* Kakugo A*
Sci. Rep. 2018, 8:11756
This research was supported by the Grant-in-Aid for Scientific Research on Innovative Areas
“Molecular Robots” (JSPS KAKENHI Grant Number JP24104004).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
29
IL5-8
Polysaccharide-based ionic hydrogel
Kun Yan Sui§§§
, Xiao Hui Zhang, Nan Nan Sheng, Hui Lin Cui, Na Pan
(State Key Laboratory of Bio-fibers and Eco-textiles, College of Materials Science and Engineering, Shandong Collaborative
Innovation Center of Marine Biobased Fibers and Ecological Textiles, Institute of Marine Biobased Materials, Qingdao University,
Qingdao 266071, China.)
*E-mail: [email protected]
Polysaccharides have become an ideal material for the preparation of
high-performance hydrogels due to their reproducibility, biocompatibility and
biodegradability. The prepared hydrogel has been widely used in soft robots, flexible
electronic devices, sensors, and biomedicine. Recently, we have fabricated a new
skin-inspired ionic hydrogel sensor composed of supramolecular SA nanofibrils by
salting-out of NaCl and chemically crosslinked PAM. The hydrogels exhibited
excellent mechanical properties and sensitive properties which could immediately and
stably monitor human motion from large movement (limbs) to small deformation
(pronunciation, pulse). In addition, we have described an extremely simple and
ultra-fast procedure (10 s-30 min) for one-step synthesis of the gradient
all-polysaccharide polyelectrolyte complex hydrogel film using diffusion-driven
interfacial reaction. The all-polysaccharide actuators can address the challenge of
simultaneously improving the mechanical properties (2.26 MPa), response kinetics (2
s) and programmable locomotion capability for practical applications. This new
synthesis strategy provides guidance for fabricating biodegradable and biocompatible
hydrogel actuators with applications in tissue engineering, soft robotics and active
implants.
Keywords: Polysaccharides, Polyelectrolyte, Hydrogel, Sensor, Actuators
References:
[1] X. H. Zhang, N. N. Sheng, L. N. Wang, Y. Q. Tan, C. Z. Liu, Y. Z. Xia, Z. H.
Nie*, K. Y. Sui*. Mater. Horiz. 2019, 6, 326-333.
[2] H. L. Cui, N. Pan, W. X. Fan*, C. Z. Liu, Y. H. Li, Y. Z. Xia, K. Y. Sui*. Adv.
Funct. Mater. 2019, 1807692.
This research was supported by the National Natural Science Foundation of China (Grant No.
51573080 and 51873094).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
30
OL 1-1
Super-elastic and multifunctional polymer hydrogel strengthened by
low-content cement-released nanoparticles
Guo Xing Sun1,2****, Rui Liang1, Xiao Sai Hu1, Xiao Xu Liang1, Hong Yao Ding1
(1 Joint Key Laboratory of the Ministry of Education, Institute of Applied Physics and Materials
Engineering, University of Macau, Avenida da Universidade, Taipa, Macau SAR, China. 2 Department of Physics and Chemistry, Faculty of Science and Technology, University of Macau,
Avenida da Universidade, Taipa, Macau SAR, China.)
*E-mail: [email protected]
Portland cements are innovatively used to obtain sub-5 nm particles. Such novel
cement-released nanoparticles pioneer super-elastic and multifunctional polymer
hydrogel, and drying-resistance oil gel. The calcium hydroxide nano-spherulites (CNS)
with diameters < 5 nm release from the surface of cement particles when cement
particles are dispersed in water at 0℃. A very low content of CNS can remarkably
strengthen and tough polymer hydrogels due to the small size effect of CNS. The
poly(acrylamide) (PAM)/ CNS hydrogel cross-linked by 40 ppm CNS can be
stretched to more than 100 times strain with a stress of more than 500 KPa. The poly
(acrylic acid) (PAA)/CNS super-adsorbent hydrogel enhanced by 200 ppm CNS
shows excellent adsorption capacity for the removal of methylene blue dye (2,100
mg/g). Furthermore, conductive polymer/CNS hydrogel possesses high electrical
conductivity (20,830 S/m) and can be stretched up to 1,076% strain, showing
potential application in flexible stretchable electronic devices. PAM/ CNS hydrogel
also exhibits excellent cell adhesion property, which is expected to become artificial
biological tissues with super-enhanced mechanical properties.
Keywords: Gel, Calcium hydroxide nano-spherulites, Super-elastic, Multifunctional
References:
[1]. Sun GX.; Li ZJ*; Liang R.; Weng LT.; Zhang LN, Nat. Commun. 2016, 7, 12095.
[2]. Hu XS.; Liang, R.; Sun GX*, J Mater Chem A. 2018, 36, 17612.
This research was supported by Science and Technology Development Fund from Macau
(FDCT-078/2017/A2).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
31
OL 1-2
OSA-AM hydrogel with high-strength and faster self-healing
property from sodium alginatei
Ya Ping Li, Hu Wei Xin, Ling Bin Lu*
(School of Materials Science and Engineering, Hainan University, Haikou, 570228, China)
*E-mail: [email protected]
With the capability of being repaired by themselves after mechanical damage,
traditional self-healing hydrogels are fragile or have unsatisfactory recovery
capability, which limit their applications. Currently, enhanced mechanical properties
and healing time of self-healing hydrogels are focused on. In this work, as a raw
material, sodium alginate was oxidized in order to introduce aldehyde groups. Then
the oxidized sodium alginate (OSA) and acrylamide (AM) interacted. Finally, the
OSA-AM hydrogel was formed via the chemical crosslink between aldehyde groups
and amide groups. The dynamic Schiff base between OSA and AM enabled the
OSA-AM hydrogel to sense the defect and to heal up without external interaction.
Further, hydrogen bonds between these two compounds enhanced the capability.
Shorter healing time (less than 1h) was achieved. At the same time, the hydrogel
possessed high fracture strength. Hence, the OSA-AM hydrogel has potential
promising application in the field of smart biomedical materials, such as artificial
skins.
Keywords: Hydrogel, Alginate, Acrylamide, Self-healing, Schiff base
References:
[1]. Liu SL.; Kang MM.; Li KW.; Yao F.; Oderinde O.; Fu GD*.; Xu LQ*, Chemical
Engineering Journal. 2018, 334, 2222
[2]. Jing X.; Mi HY.; Napiwocki B.; Peng XF*, Carbon. 2017, 125, 557
[3]. Sun CY.; Jia HY.; Lei K.; Zhu DD.; Gao YH.; Zheng Z.; Wang XL*, Polymer.
2019, 160, 246
[4]. Cai TT.; Huo SJ,; Sun WX.; Wang T*; Tong Z**, Carbohydrate Polymers. 2018,
193, 54
This work was supported by the Key Research and Development Program of Hainan
Province (No.ZDYF2018016), and the Project supported by the Education
Department of Hainan Province (No.Hnky2019ZD-5).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
32
OL 1-3
High Strength Globular Protein Hydrogels
Qiang Chen1,††††, Ziqing Tang1, Zhao Liu1, Lin Zhu
(1School of Materials Science and Engineering, Henan Polytechnic University, Jiaozuo 454000,
China.)
*E-mail: [email protected]
Developing functional hybrids of globular proteins and synthetic polymers into
multipurpose tough hydrogels remain to be challenging. Here, we propose a new
strategy combining double network and protein misfolding concepts to create diverse
protein/polymer double-network (DN) hydrogels with both high bulk and interfacial
toughness. The method integrates an intrinsic heat-induced protein
denaturation/aggregation feature and a double-network concept that produce different
bovine serum albumin (BSA)-based DN hydrogels with hybrid physical-chemical
crosslinking or fully physical crosslinking to achieve high modulus of 252-1199 kPa,
high strength of 0.24-0.48 MPa, high fracture energy of 3.56-16.88 MJ/m3, high
extensibility of 7.7-79.9 mm/mm, fast self-recovery (stiffness/toughness recovery of
94%/80% after heat treatment at 80 oC for 30 min), and strong surface adhesion to
various nonporous solid surfaces (interfacial toughness of 1176-2827 J/m2). Such
tough and adhesive protein/polymer hydrogels have great potentials for different
applications of artificial soft tissues, flexible electronics, and wearable devices.
Keywords: Double-Network Hydrogels, Globular Protein, High Strength,
Self-Recovery, Tough Adhesion
References:
[1]. Tang ZQ.; Chen Q*.; Chen F.; Zhu L.; Lu SP.; Ren BP.; Zhang YX.; Yang J.;
Zheng J* , Chem. Mater. 2019, 31,179
This research was supported by the National Natural Science Foundation of China (Grant No.
21504022 and U1304516).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
33
OL 1-4
Multiple Functions of High Performance Hydrogels Enhancement by
Hydrogen Bond
Xuefeng Li, Xueyin Peng, Rongzhe Li
(Hubei Provincial Key Laboratory of Green Materials for Light Industry, School of Materials
Science and Engineering, Hubei University of Technology, Wuhan 430068, P. R. China.)
*E-mail: [email protected].
A new class of polymer hydrogels with H-bonding and metal-coordination dual
physically crosslinked networks is successfully designed. The nature of physical
crosslinks makes the hydrogel network self-recoverable, and enables dissipation of
mechanical load through energy-dissipating sacrificial linkages mechanisms.[1-2]
In this study, we chose a functional monomer 2-Vinyl-4,6-diamino-1,3,5-triazine
(VDT), whose Diaminotriazine (DAT) moieties are capable of forming strong and
stable H-bonding in water. copolymerization of VDT, acrylic acid (Ac) and
acrylamide (Am) to form a preformed gel (P-gel). Then, soaking the P-gel in Fe3+
aqueous solution to form carboxylic-Fe3+ coordination to obtain S-hydrogel which has
a good potentials for stable and strong physical interaction. Afterwards, a dual
physically cross-linked hydrogel (D-hydrogel) was finally prepared by soaking the
S-hydrogel in deionized water to remove free Fe3+ that probably enabled final
stabilization of both the H-bonds and the ionic coordination. As a result, D-hydrogel
with excellent mechanical properties and self-recoverable properties. Figure 1 depicts
formation of the dual physical crosslinks.
Figure 1. Schematic diagram of the formation of a D-hydrogel with dual physical crosslinking.
In order to study potentials of the D-hydrogel for physical adsorption in aqueous
phase. We have synthesized PVDT nanoparticles which has a capacity of quick
adsorption of uric acid in pH 7.4 phosphate buffered saline. The mechanism for the
adsorption was ascribed to simultaneous formation of three H-bonds between the
DAT moieties and each of the target molecules (Figure 2(a)). The 5-Fu was chosen as
a guest molecule and the D-hydrogels fabricated with different VDT contents were
used to investigate the correlation between the DAT content in the copolymers and
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
34
their adsorption capacities. Figure 2(b) shows a clear downward trend in absorbance
at 292 nm as the VDT content gradually increased in the copolymer. Finally, the
quantity of 5-Fu adsorbed by each gram of the copolymer was calculated and shown
in Figure 2(c).
Figure 2. H-bonding between DAT group and 5-Fu molecule (a). Absorbance of 292 nm
corresponds to the change of 5-Fu concentration (b). Capacity of 5-Fu adsorption with varied VDT
content in the D-hydrogels (c).
As we known, capacitive sensor can be applied to detect human motion and
complicate muscle movements as ionic skin sensor. We soaked the D-hydrogel in
lithium chloride solution to allow the D-hydrogel absorb conductive Li+. As shown in
Figure 3(a), we constructed a capacitive pressure sensor by integrating two hydrogel
films with a dielectric layer (polyethylene terephthalate film). The D-hydrogel-Li+
was the conductive layer, in which Fe3+ and freely moving Li+ provide good
conductivity. Figure 3(b) shows the sensor is attached to the finger. When the finger is
bent, the capacitance undergoes a stable and repeatabie change.
Figure 3. Schematic design of the D-hydrogel-Li+ capacitive sensor as ionic skin (a). Real-time
capacitance signals when the finger bends cyclically and photos of hydrogel sensors attached to a
bent or straight finger (b).
Therefore, Dual physical crosslinks of H-bonding and ionic coordination
significantly enhanced the hydrogel mechanical properties. Incorporation of VDT
units into the copolymer chains endued the hydrogel with capacity of physical
adsorption of antitumor 5-Fu, and ionic coordination provided good conductivity after
absorbing Li+. These applications show that D-hydrogel-Li+ based ionic skin has great
potential as a highly sensitive pressure and strain sensor for AI and wearable devices.
Keywords: High strength hydrogel; Diaminotriazine; Integrated Functional;
Synergistic effect.
References:
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
35
[1]. J. P. Gong, Y. Katsuyama, T. Kurokawa, Adv. Mater. 2003, 15, 1155.
[2]. D. D. Lane, S. Kaur, G. M. Weerasakare, Soft. Matter. 2015, 11, 6981.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
36
OL 1-5
Predictions of Thermo‐Mechanical Properties of Cross‐Linked
Polyacrylamide Hydrogels Using Molecular Simulations
Meng An1,3,*, Baris Demir2, Xiao Wan3, Han Meng3, Nuo Yang3, and Tiffany R.
Walsh2
( 1College of Mechanical and Electrical Engineering, Shaanxi University of Science and
Technology, 6 Xuefuzhong Road, Weiyangdaxueyuan, Xi’an 710021, P.R. China. 2Institute for
Frontier Materials, Deakin Unviersity, Geelong, VIC 3216, Austrailia. 3Nano Interface Center for
Energy, School of Energy and Power Engineering, Huazhong University of Science and
Technology, Wuhan, 430074, P.R. China)
*E-mail: [email protected]
Hydrophilic acrylamide‐based hydrogels are emerging platforms for numerous
applications, but the resources to fully exploit these materials are currently limited. A
deep understanding of the molecular‐ level structure/property relationships in
hydrogels is crucial to progressing these efforts. Such relationships can be challenging
to elucidate on the basis of experimental data alone. Here, molecular simulations are
used as a complementary strategy to reveal the molecular‐level phenomena that
govern the thermo‐mechanical properties of hydrogels. The focus is on acrylamide
‐based hydrogels cross‐linked with N,N′‐methylenebisacrylamide, generated
using previously established computational cross‐linking procedure. The water
content is found to be a key determinant in the elastic response of these hydrogels,
with enhanced tensile and shear properties at low water content. However, it is also
found that increasing water content enhances the hydrogel's thermal conductivity,
with the dominant contribution arising from the non‐bonded contributions to the
heat flux. In addition, chemical cross‐linking improves the heat transfer properties
of the hydrogel, whereas a reduction in convective heat transfer is predicted with an
increase in hydrogel cross‐linking. These simulations provide a rational basis for
designing and testing customized hydrogel formulations for maximizing both thermal
conductivity and mechanical properties.
Keywords: Cross-linking, Hydrogels, Molecular dynamics simulations,
Polyacrylamides, Thermal conductivity
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
37
References:
[1]. Meng A., Baris D.; Xiao W., Han M.; Nuo Y.; Tiffany R., Adv. Theor.
Wei Z.; Yang JH.; Liu ZQ.; Xu F.; Zhou JX.; Zrínyi M.; Osada Y.; Chen YM* ,
Adv. Theory Simul. 2019, 2,1800153.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
38
OL 1-6
Solvent responsive ultra-strong shape memory gels based on
hydrophobic association with fantasy applications
Tao Wang1‡‡‡‡, Jiexin Liao1, Jiahe Huang1, Shurui Yang1, Weixiang Sun1, Zhen Tong1,
2*
(1Research Institute of Materials Science and 2State Key Laboratory of Luminescent Materials and
Devices, South China University of Technology, Guangzhou 510640, China.)
*E-mail: [email protected] (T. Wang), [email protected] (Z. Tong)
Introduction of hydrophobic association through copolymerization in water or in
organic solvents followed by solvent exchange provided an effective and facile
approach to reinforce gels and realize shape memory or other capabilities. However,
fast response rate and multifunctional applications still need to be explored to broaden
the applications in soft actuator and biomedical fields. Novel ultra-strong hydrogels
with rapid solvent responsive shape memory behavior were prepared through the
association of monomers with hydrophobic side groups such as dopamine
methacrylamide and butyl methacrylate. The gels were synthesized in water and
DMSO mixed solvent, while the ultra-strong hydrogels with strength up to 9 MPa and
modulus of 200 MPa were obtained through solvent in water. At the same time, the
formation and dissociation of the hydrophobic association showed excellent
reversibility, which endowed the gels with solvent induced shape memory and
actuating capabilities. In addition, solvent leakage warning system, sustainable and
erasable “gel paper”, bioinspired bilayer flower and other soft actuators were designed
to explore the fantasy applications of these multifunctional strong gels.
Keywords: Ultra-strong gels, Shape memory, Hydrophobic association, Actuator
This research was supported by the NSFC (51573060 and 21427805) and the Pearl River S&T
Nova Program of Guangzhou (201710010146).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
39
OL 1-7
Electroactive Hydrogels: synthesis, characterization and application
Zhijun Shi1,, Li Wang1, Sanming Hu1, Guang Yang1*
(1 Department of Biomedical Engineering, College of Life Science and Technology, Huazhong
University of Science and Technology, Wuhan 430074, PR China.)
*E-mail: [email protected]
Hydrogels prepared from natural polymers have received immense
considerations over the past decade due to their safe nature, biocompatibility,
hydrophilic properties, and biodegradable nature. More recently, when treated with
electroactive materials, these hydrogels were endowed with high electrical
conductivity, electrochemical redox properties, and electromechanical properties;
consequently, forming an electroactive hydrogel. These hydrogels are good candidate
materials for use in biomedical devices, such as biosensors, electro-stimulated drug
release devices, bioactuators, nanogenerators, and implanted electrodes. To further
explore the applications of electroactive hydrogel in biomedical field, one promising
strategy is to make electroactive hydrogel with similar ordered structure with natural
tissue or organ, or guide the cell alignment to form ordered multicellular structures,
and finally, make the artificial tissues or organs perform their functions. In this work,
we fabricated electroactive hydrogel with ordered 2D/3D microstructure. On the basis
of culture protocol on these materials involving the systematic delivery of intermittent
electric field stimulation, both the microstructured substrate and electric field strength
will be established to promote cellular activities such as cell division, migration,
differentiation and designificant morphological extensions. And then we will examine
the mechanisms of the cellular activities under the impact of the two cues to study
further about the enhancement of interaction of contact guidance with electric field in
guiding cells, which will be fundamental in skin/cornea wound healing, nerve orderly
regeneration, vascular tissue engineering, etc.
Keywords: bacterial cellulose, electroactive hydrogel, ordered 2D/3D microstructure,
electric stimulation
References:
[1] Shi, Z., Shi, X., Ullah, M.W. et al. Adv Compos Hybrid Mater, 2018, 1: 79.
[2] Shi, Z., Gao, X., Ullah, M. W., Li, S., Wang, Q., & Yang, G. Biomaterials, 2016,
40-54.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
40
OL 1-8
Highly-tough single-network polysaccharide hydrogel
Chaoxi Wu1§§§§, Yifei Wang
(1†Guangzhou Jinan Biomedicine Research and Development Center, Institute of Biomedicine,
College of Life Science and Technology, and ‡Biomedical Engineering Institute, Jinan University,
Guangzhou 510632, China.)
*E-mail: [email protected]
Polysaccharides are biocompatible and biorenewable polymers which are very
frequently used in the formation of hydrogels. However, most polysaccharide
hydrogels are fragile with low stretchability, which largely limit their applications.
Currently no polysaccharide hydrogel can stretch to over 1.5 times of its original
length without break. Here a novel polysaccharide hydrogel with extremely high
stretchability are reported in this work. This hydrogel can stretch to >2.5 times of its
original length and exhibit a tensile strength of >1 MPa. This polysaccharide hydrogel
is solely based on beta-glucan, which is known to form very stiff triple helix. The new
method have successfully triggered the beta-glucan molecules to pack into triple
helices and then into nanofiber network. This hydrogel have high crystallinity and
advanced network structure, which is utterly different from previous beta-glucan
hydrogel. This highly stretchable beta-glucan hydrogel may be used in tissue
engineering and wound dressing due to its good mechanical properties.
This research was supported by Pearl River S&T Nova Program of Guangzhou (706065366041)
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
41
Keywords: Single network, polysaccharide, highly tough, hydrogel
References:
[1]. Self-Assembly of Core Corona beta-Glucan into Stiff and Metalizable Nanostructures from 1D
to 3D 作者: Wu, Chaoxi; Wang, Xiaoying; Chu, Bin; 等.
ACS NANO 卷: 12 期: 10 页: 10545-10553 出版年: OCT 2018
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
42
OL 1-9
Molecular engineering of metal-coordination interactions for strong,
tough and fast-recovery hydrogels
Wenxu Sun1, Bin Xue1, Yi Cao1*****
(1 Collaborative Innovation Center of Advanced Microstructures, National Laboratory of Solid
State Microstructure, and Department of Physics, Nanjing University, Nanjing 210093, China.)
*E-mail: [email protected]
Many load-bearing tissues, such as muscles and cartilages, show high elasticity,
toughness and fast recovery. However, combining these mechanical properties in the
same synthetic biomaterials (i.e. hydrogels) is fundamentally challenging as they
require contradictive mechanical and dynamical properties of the cross-linkers. For
example, hydrogels cross-linked by stable bonds are strong but recover slowly and
hydrogels cross-linked by dynamic bonds recover quickly but are mechanically weak.
Here, we show that strong, tough and fast-recovery hydrogels can be engineered using
cross-linkers involving cooperative dynamic interactions. We designed a
histidine-rich decapeptide containing tandem repeats of two zinc binding motifs. This
decapeptide had a stronger binding strength, higher thermodynamic stability, and
faster binding rate than single binding motif or isolated ligands (histidine). The
engineered double-network hydrogels containing the peptide-metal complex exhibit a
high elasticity of ~300 kPa, ultratoughness of ~1,500 kJ m-3 and fast recovery in
seconds under multiple load-unload cycles, comparable to mechanical properties of
articular cartilage. We expect that they can function effectively as scaffolds for
load-bearing tissue engineering and as building blocks for soft robotics. Our results
provide a general route to tune the mechanical and dynamic properties of hydrogels at
the molecular level.
Keywords: Gel, Fast-recovery, Metal chelation, Cooperativity, Toughness
This research was supported by the National Natural Science Foundation of China (Grant No. No.
21522402, 11674153, 81622033, 21774057 and 11804148).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
43
OL 1-10
Injectable Hydrogel Formed by Metal–Ligand Coordination
Assembly as Biomaterials
Liyang Shi†††††
(State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, Hunan
University, Changsha 410082, China.)
*E-mail: [email protected]
Hydrogels are 3D polymeric cross-linked networks that retain substantial amounts
of water that are promising biomaterials in the fields of tissue engineering, drug
delivery, and biosensing etc. Particularly, the presented hydrogels based on
metal-ligand coordination chemistry provide new and exciting properties that improve
injectability, rheological behaviors, and even biological functionalities.[1] In my works,
several injectable hydrogels crosslinked by bisphosphonate (BP) and metal ions or
metallic nanoparticles were fabricated, which showed self-healing and shear-thinning
because of the inherent reversibility of BP-metal coordination bonds. [2-5] To prepare
the meal-BP based hydrogel, we firstly conjugated the BP groups on the backbones of
hyaluronic acid (HA) followed by introducing the metal sources into the BP modified
HA (HA-BP) solution. Specifically, two types of metal ions (i.e., Ca2+ and Ag+ ions)
as well as two types of metal salts particles (i.e., calcium phosphate coated silk
microfibers (CaP@mSF) and magnesium silicate (MgSiO3) nanoparticles) were used
to generate the hydrogels. Additionally, the hydrogels can form a secondary
cross-linkage with covalent bonds under UV curing. The presented four types of
HA-BP based hydrogels were applied in several biomedical applications such as 3D
printing, wound healing, bone regeneration, and controlled anticancer drug delivery.
Compared with the non-dynamic bonds forming injectable hydrogels based on
cross-linking of liquid polymer precursors during or after injection, my meal-BP
based hydrogels exhibited unlimited time window for injection.
Keywords: Bisphosphonate, Biomaterials, Coordination Chemistry, Injectable
Hydrogels
References:
[1] Shi, L.; Ding, P.; Wang, Y.; Zhang, Y.; Ossipov, D.; Hilborn, J., Self-Healing
Polymeric Hydrogel Formed by Metal-Ligand Coordination Assembly: Design,
Fabrication, and Biomedical Applications. Macromol. Rapid Commun. 2019,
This research was financially supported by the Fundamental Research Funds for the Central
Universities (No. 531107051242).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
44
e1800837.
[2] Shi, L.; Carstensen, H.; Hölzl, K.; Lunzer, M.; Li, H.; Hilborn, J.; Ovsianikov, A.;
Ossipov, D. A., Dynamic Coordination Chemistry Enables Free Directional Printing
of Biopolymer Hydrogel. Chem. Mater. 2017, 29 , 5816-5823.
[3] Shi, L.; Wang, F.; Zhu, W.; Xu, Z.; Fuchs, S.; Hilborn, J.; Zhu, L.; Ma, Q.; Wang,
Y.; Weng, X.; Ossipov, D. A., Self-Healing Silk Fibroin-Based Hydrogel for Bone
Regeneration: Dynamic Metal-Ligand Self-Assembly Approach. Adv. Funct. Mater.
2017, 27,1700591.
[4] Shi L., Zhao Y., Xie Q., Fan C., Hilborn J., Dai J., Ossipov D. Moldable
hyaluronan hydrogel enabled by dynamic metal-bisphosphonate coordination
chemistry for wound healing, Adv. Healthc. Mater. , 2018, 7,1700973.
[5] Shi, L.; Han, Y.; Hilborn, J.; Ossipov, D., "Smart" drug loaded nanoparticle
delivery from a self-healing hydrogel enabled by dynamic magnesium-biopolymer
chemistry. Chem. Commun. 2016, 52 , 11151-11154.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
45
OL 1-11
Fabrication of chitosan functionalized graphene oxide-embedded
nanocomposite hydrogels with enhanced mechanical properties
Sijun Liu‡‡‡‡‡
(Advanced Rheological Institute, Department of Polymer Science and Engineering,
Shanghai Jiao Tong University, Shanghai 200240, P. R. China.)
*E-mail: [email protected]
Chitosan hydrogel formed by the traditional acidic dissolved method usually
exhibits poor mechanical property. To break this limitation, the alkali/urea solvent
system was created to dissolve chitosan via the freezing−thawing process, and then a
bended chitosan physical hydrogel was prepared after immersing hot water to remove
alkali and urea. In this study, we fabricated an enhanced chitosan nanocomposite
hydrogel based on the alkali/urea aqueous solvent. Frist of all, the covalent
functionalization of graphene oxide (GO) with chitosan (CS) was successfully
accomplished via a facile amidation process. Secondly, the chitosan nanocomposite
hydrogel (Chi-CGO) was constructed by combing chitosan-grafted graphene oxide
(CGO). The experimental results indicated that the presence of CGO greatly enhanced
the mechanical property of chitosan hydrogel, for example, the elastic modulus and
strain at break of Chi-CGO0.5 respectively increased by 3.2 and 1.8 times in contrast
to the pure Chi. Most importantly, the resulted Chi-CGO hydrogel demonstrates an
excellent biocompatibility. This novel strategy greatly enriches the construction of
chitosan hydrogels with good mechanical properties and expands its application in the
area of tissue engineering.
Keywords: Chitosan, nanocomposite hydrogel, graphene oxide
References:
[1]. H. Bao, Y. Pan, Y. Ping, N. G. Sahoo, T. Wu, L. Li,* J. Li, and L. H. Gan, Small,
2011, 7, 1569.
[2]. J. Duan, X. Liang, Y. Cao, S. Wang, and L. Zhang*. Macromolecules, 2015, 48,
2706.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
46
OL 1-12
Freezing-Tolerant Gelatin Organohydrogels with High Mechanical
Performances, Thermoplasticity, and Adhesivity
Zhi Hui Qin1, Fang Lian Yao1,2,3*, Jie Jun Li1,3*
(1 School of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, China; 2
School of Materials Science and Engineering, East China Jiaotong University, Nanchang 330013,
China;3 Key Laboratory of Systems Bioengineering of Ministry of Education, Tianjin University,
Tianjin 300350, China.)
*E-mail: [email protected]
Relative low mechanical strength and the deterioration of desirable performances at
subzero temperatures are the two main deficiencies facing natural polymer-based
hydrogels, which severely limits their applications. Here, we report a high-mechanical
and anti-freezing protein-based organohydrogel by applying a simple strategy of
immersing a virgin gelatin hydrogel into citrate (Cit) water-glycerol mixture solution.
In the organohydrogel, a part of water molecules are replaced by glycerol, which
inhibits the formation of ice crystallization even at extremely low temperature. The
formation of hydrophobic aggregation induced by the salting-out effect, ionic
interaction between the –NH3+ of gelatin chains and Cit3− anions, as well as hydrogen
bond between gelatin chains and glycerol during the immersing procedure endows the
organohydrogels with high strength and toughness. The organohydrogel can maintain
their mechanical flexibility even at -80 °C. Moreover, owing to reversible nature of
physically crosslinked domains, the organohydrogels display intriguing remoldability,
good healing ability and excellent adhesive behavior at various substrates.
Keywords: organohydrogel, anti-freezing, high strength, remoldability, non-covalent
interactions
References:
[1]. Rong, Q.; Lei, W.; Chen, L.; Yin, Y.; Zhou, J.; Liu, M. Anti-freezing, Conductive
Self-Healing Organohydrogels with Stable Strain-Sensitivity at Subzero Temperatures.
Angew. Chem., Int. Ed. 2017, 56, 14159-14163.
[2]. Morelle, X. P.; Illeperuma, W. R.; Tian, K.; Bai, R.; Suo, Z.; Vlassak, J. J. Highly
Stretchable and Tough Hydrogels below Water Freezing Temperature. Adv. Mater.
2018, 30, 1801541.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
47
Acknowledgments
This work is supported by The Excellent Young Scientists Fund by National
Natural Science Foundation of China (No. 31722022), National Nature Science
Foundation of China (No. 51573127, 51733006, 31870948) and National Key
Research and Development Program of China (No. 2018YFC1105502).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
48
OL 1-13
Electrochemical analysis of bovine serum albumin imprinting CaAlg
based composite hydrogel sensor
Meng Qi1,2§§§§§, Kongyin Zhao1, 2, Lun Xia1
(1State Key Laboratory of Separation Membranes and Membrane Processes, Tianjin 300387,
China; 2School of Material Science and Engineering, Tianjin Polytechnic University, Tianjin
300387, China.)
*E-mail: [email protected]
The BSA electrochemical imprinted hydrogel sensor was fabricated by
introducing the organic-inorganic hybrid structure between calcium silicate/
mesoporous silica gel (CaSiO3@SiO2) and CaAlg into CaAlg hydrogel system onto
modified bare carbon electrodes. Due to the hydrogen bond interaction between
mesoporous silica gel and CaAlg, the mechanical and anti-swelling performance of
alginate hydrogel membrane had been significantly improved. It can be detected
quickly by voltammetry curves that the hydrogel sensor can quickly removed the
template molecules BSA in Tris-HCl buffer (pH=7.4). After five rebinding and
releasing cycles, the affinity of MIP sensor to BSA still remained above 80%,
indicating that MIP sensors possessed superior stability. MIP modified electrode also
showed good dynamic response in the range of 0.5~100 μmol*L-1 BSA concentration.
In addition, MIP hydrogel sensors monitored the selectivity of some protein similar
molecular weight and structure to BSA, such as bovine hemoglobin (BHb) and
ovalbumin (OVA). Therefore, it will have great potential applications in protein
release and sensor.
Keywords: Calcium alginate; Organic-inorganic; Bovine serum albumin;
Electrochemical imprinting hydrogel sensor
This research was supported by the National Natural Science Foundation of China (51708407) and
Tianjin Science Technology Research Funds of China (16JCZDJC37500).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
49
OL 1-14
Ultrastiff and tough hydrogels with dense and robust hydrogen bond
complexes
Xin Ning Zhang1, Yan Jie Wang1,2, Hongyao Ding1, Yiping Zhao2, Zi Liang Wu1*,
Qiang Zheng1
(1 Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027,
China; 2 School of Materials Science and Engineering, Tianjin Polytechnic University, Tianjin
300387, China)
*E-mail: [email protected]
Hydrogels are usually recognized as soft and weak materials, the poor mechanical
properties of which greatly limit their applications as structural elements. So far, a
variety of tough hydrogels with typical network structures and different toughening
mechanisms. Some synthetic hydrogels are even tougher than soft biotissues.
However, in terms of stiffness, the tough hydrogels (Young’s modulus E: 0.01–1 MPa)
are much softer than the cartilages and skins (E up to 100 MPa). Although soft
hydrogels can achieve high strength and toughness via high stretchability, certain
applications of tough gels as structural elements still require high stiffness. Therefore,
designing tough and stiff hydrogels has both fundamental and practical significances.
Recently, we developed a series of tough and stiff hydrogels by forming dense and
robust hydrogen bonds between vinylimidazole and acrylic acid groups, which are
stabilized by the neighboring hydrophobic methyl groups. The resultant hydrogels
with water content of 50-60 wt% are stable in water and possesse excellent
mechanical properties, with tensile breaking stress, breaking strain, and Young's
modulus of 1-10 MPa, 100-600%, and 10-200 MPa, respectively. The dynamic nature
of hydrogen bonds also affords the hydrogels versatile functions, such as shape
memory, self-recovery, etc. These tough and stiff hydrogels should be an ideal
material as structural materials with promising applications in diverse fields.
Keywords: hydrogels, toughness, stiffness, hydrogen bonds
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
50
OL 1-15
Anisotropic All-Cellulose 3D Wrinkled Hydrogels with
Programmable Patterns for Cells Alignment
Dongdong Ye1******, Jie Zou1, Lina Zhang2
(1School of Textile Materials and Engineering, Wuyi University, Jiangmen 529020, China; 2College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China)
*E-mail: [email protected]
Wrinkled hydrogels from biomass sources are expected as potential structural
biomaterials. However, for bio-related applications, a scalable, structure-customized,
mechanically stable and biocompatible wrinkled hydrogels engineered with high
oriented nanostructure and controllable intervals is still a challenge. Herein, we
reported a scalable biomass material, namely cellulose for customizing wrinkled
hydrogels through an ultrafast acid-induced interface reconfiguration under
confinement in NaOH/urea aqueous system. After immersing a pre-stretched chemical
gel in an acid solution and relaxation within 20s, a fixed and strengthened of
outermost oriented structure was built, resulting in a consecutive outside-to-inside
modulus gradient and a self-wrinkled structure. The structure of wrinkled hydrogels
were programmable by tuning prestretching strains and reacting time for successfully
inducing cells alignment. We have opened up a new avenue to fabricate
polysaccharides-derived programmable oriented wrinkled hydrogels for biomedical
materials via a bottom-up method.
Keywords: Cellulose hydrogels, Wrinkled structure, Modulus gradient, Bottom-up
approach, Cells alignment
References:
[1]. Ye DD.; Yang PC.; Lei XJ.; Zhang DH.; Li LB., Chang CY*., Sun PC.; Zhang
LN*, Chem. Mater, 2018, 30, 5175-5183.
[2]. Ye DD.; Lei XJ.; Li T.; Cheng QY.; Chang CY.; Hu LB*.; Zhang LN*, ACS
Nano, 2019, 13, 4843-4853.
This research was supported by the scientific research startup funds for high-level talents of Wuyi
University (AL2018010).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
51
OL 1-16
An injectable self-assembling collagen-gold hybrid hydrogel for
combinatorial antitumor photothermal/photodynamic therapy
Ruirui Xing1,2,3, Kai Liu3, Tifeng Jiao1,2,*, Ning Zhang3, Kai Ma1,2, Ruiyun Zhang1,2,
Qianli Zou3,*, Guanghui Ma3, Xuehai Yan3,*
(1State Key Laboratory of Metastable Materials Science and Technology, Yanshan University,
Qinhuangdao 066004, P. R. China; 2Hebei Key Laboratory of Applied Chemistry, School of
Environmental and Chemical Engineering, Yanshan University, Qinhuangdao 066004, P. R. China; 3National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese
Academy of Sciences, Beijing 100190 , P. R. China)
*E-mail: [email protected] (T. Jiao); [email protected] (Q. Zou); [email protected] (X. Yan).
An injectable and self-healing collagen-protein-based hydrogel is formed by a
gold-biomineralization-triggered self-assembly, which was mainly associated with the
electrostatic interaction between positively charged collagen chains and anionic
clusters ([AuCl4]− ions). Moreover, such biocompatible collagen-based hydrogels have
been developed as a novel tool for localized delivery and sustained release of
therapeutic drugs, with the advantages to reduce the drug dosage, to lower the toxicity,
and to improve the bioavailability. It has also been demonstrated that antitumor
efficacy can be significantly enhanced by combinatorial PTT/PDT treatments, without
pathologic lesion for primary organs, merely through one intratumoral injection of the
collagen-based hydrogels and increasing the laser irradiation times. Overall, the
injectable and self-healing collagen-based hydrogels we developed offer new
alternative opportunities for development of protein-based delivery vehicles and a
treatment strategy toward a broad range of biomedical applications such as drug
delivery and tissue engineering.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
52
Keywords: Collagen-based hydrogel, Injectable, Self-healing, Biomedical
References:
[1] Xing RR.; Liu K.; Jiao TF.; Zhang N.; Ma K.; Zhang RY.; Zou QL.; Ma GH.; Yan
XH, Adv. Mater. 2016, 28, 3669-3676.
[2] Zhang RY.; Xing RR.; Jiao TF.; Ma K.; Chen CJ.; Ma GH.; Yan XH, ACS Appl.
Mater. Inter. 2016, 8, 13262-13269.
[3] Xing RR.; Jiao TF.; Yan LY.; Ma GH.; Liu L.; Dai LR.; Li JB.; Möhwald H.; Yan
XH, ACS Appl. Mater. Inter. 2015, 7, 24733-24740.
[4] Xing RR.; Jiao TF.; Ma K.; Ma GH.; Möhwald H.; Yan XH, Sci. Rep. 2016, 6,
26506.
-------------------------------------------
This research was supported by the National Natural Science Foundation of China (Grant No.
21872119), Support Program for the Top Young Talents of Hebei Province, and Research Program
of the College Science & Technology of Hebei Province (No. ZD2018091).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
53
OL 1-17
PAM/CaAlg/CaSiO3@SiO2 composite hydrogel with high strength,
good transparency and low swelling under physiological environment
Kong Yin Zhao1,2††††††, Meng Qi1, Guo Qing Xu1
(1State Key Laboratory of Separation Membranes and Membrane Processes, Tianjin Polytechnic
University, Tianjin 300387, China;2School of Material Science and Engineering, Tianjin
Polytechnic University, Tianjin 300387, China.)
*E-mail: [email protected]
High strength PAM/CaAlg/CaSiO3@SiO2 composite hydrogel with high strength,
good transparency and low swelling under physiological environment was prepared
by dissolving sodium silicate, acrylamide (AM) and sodium alginate (NaAlg) in water,
inducing acrylamide polymerization, crosslinking sodium alginate with calcium ion
and soaking in gluconic acid-gain-lactone (GDL) aqueous solution. Organic-inorganic
hybrid structures between calcium silicate/mesoporous silica gel (CaSiO3@SiO2) and
alginate, the hydrogen bonding between CaSiO3@SiO2 nanoparticles and polymer
matrix (PAM and CaAlg) and the CaSiO3@SiO2 nanoparticles improve the stability
of the hydrogel in physiological environment. The composite hydrogel membrane was
characterized by SEM, TEM, Circular dichroism spectrum (CD) and Raman
spectrometer. The multi-scale computer simulation is developing to mathematically
describe the behavior of PAM/CaAlg/CaSiO3@SiO2 and PAM/CaAlg hydrogel. The
mechanical properties and swelling properties of the hydrogel film in saline were
discussed. The composite hydrogel membrane has solved the problem of low strength
and poor stability of the traditional hydrogel. This paper provides a novel method to
develop hydrogel materials for prospective applications in biomedicine, tissue
engineering, regenerative medicine, and optical biological devices.
Keywords: PAM/CaAlg/CaSiO3@SiO2; High strength hydrogel; Mechanical
properties; swelling properties; Stability in physiological environment
This research was supported by the National Natural Science Foundation of China (51708407) and
Tianjin Science Technology Research Funds of China (16JCZDJC37500).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
54
OL 1-18
Multicolor Fluorescent Polymeric Hydrogels: Fabrication and
Sensing/Actuating applications
Wei Lu‡‡‡‡‡‡
, Jia Wei Zhang, Tao Chen
(Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences,
Ningbo 315201, China.)
*E-mail: [email protected]
Fluorescent polymeric hydrogels are highly swollen and hydrophilic 3-D networks
with tunable luminescent properties.[1] Their hydrophilic 3-D polymeric network
structure significantly facilitate the substance exchange with surrounding aqueous
solutions to induce visible fluorescence response, making them particularly useful for
biological imaging, luminescent sensing, information encoding and transforming, etc.
However, most studies primarily focus on fluorescent polymeric hydrogels with
single-color emission, the research of multicolor fluorescent ones is highly lagging,
which seriously limits their application in many areas. To this end, we recently
produce new-type multicolor fluorescent polymeric hydrogels simultaneously grafted
with stimuli-responsive red-, green- and blue-light-emitting fluorophores. These
hydrogel films could be used to construct fluorescent chemosensors[2~4] or actuators
with on–off switchable and color-tunable fluorescence behaviors.[5~6]
Keywords: Multicolor fluorescence, Hydrogel, Chemosensors, Actuators
References:
[1] Lu, W.; Le, X.; Zhang, J.; Huang, Y. ; Chen, T., Chem. Soc. Rev. 2017, 46, 1284.
[2] Li, P.; Zhang, D.; Zhang, Y.; Lu, W.*; Wang, W.; Chen, T., ACS Sens. 2018, 3,
2394.
[3] Zhang, D.; Zhang, Y.; Lu, W.*; Le, X.; Li, P.; Huang, L.; Zhang, J.; Yang, J.;
Serpe, M. J.; Chen, D.; Chen, T., Adv. Mater. Technol. 2018, 1800201.
[4] Lu, W.; Zhang, J.; Huang, Y.; Théato, P.; Huang, Q.; Chen, T., ACS Appl. Mater.
Interfaces 2017, 9, 23884.
This research was supported by the National Natural Science Foundation of China (Grant No.
21774138, 21504100).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
55
[5] Ma, C. X.; Lu, W.; Yang, X.; He, J.; Le, X.; Wang, L.; Zhang, J.; Serpe, M.;
Huang, Y.; Chen, T., Adv. Funct. Mater. 2018, 1704568.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
56
OL 1-19
Mechano-responsive, tough and antibacterial zwitterionic hydrogels
with controllable drug release for wound healing
Kun Fang1,2, Rong Wang1,*, Donglei Liu2,*, Fanrong Ai2, Jun Fu1,*
(1Polymers and Composites Division, Ningbo Institute of Materials Technology and Engineering,
Chinese Academy of Sciences, Ningbo 315201, China; 2School of Mechanical and Electrical
Engineering, Nanchang University, Nanchang 330031, China)
*E-mail: [email protected]
Abstract: Wound treatments, especially for chronic wounds or those under stresses
and deformations, have attracted great attentions. Because of frequent external stress
or strain, the healing process of these wounds could be easily interfered, and result in
infection and delayed healing. Smart hydrogels can control drug release upon external
stimulations, such as pH, temperature, light, etc.. However, many of these hydrogels
have low mechanical property, and cannot be used for wounds under stresses and
deformations. Herein, we developed a novel tough mechano-responsive zwitterionic
hydrogel using drug-loaded acrylated Pluronic® F127 micelles as macro-crosslinker
and sulfobetaine methacrylate as monomer. Rifampicin, as a model hydrophobic
antibiotic, was loaded in acrylated F127 micelles. The hydrogel has excellent
mechanical properties, with the ultimate tensile strength and tensile strain up to 112
kPa and 1420%, respectively, and the compressive stress up to 1.41 MPa. The release
of antibiotic from the hydrogel could be controlled by the extent and cycles of
mechanical strain/stress. The hydrogel exhibits excellent antibacterial property against
Staphylococcus aureus and Staphylococcus epidermidis. In addition, drug penetration
into skin tissue was enhanced under mechanical stress of the hydrogel. Such a tough
mechano-responsive hydrogel holds great promise for chronic wound treatment.
Keywords: Mechano-responsive, antibacterial, tough hydrogels, wound healing, drug
release.
References:
[1]. Xu D.; Gao G.; Xiao Y.; Wang Z.; Chen J.; Zhou Y. Wang R.*; Yin J.*; Fu J.*, J.
Polym. Sci., Part B: Polym. Phys. 2019, 57, 473-483.
[2]. Wang R.; Chua K. L.*; Neoh K. G.*, ACS Biomater. Sci. Eng., 2015, 1, 405-415.
This research was supported by the National Natural Science Foundation of China (51803229).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
57
OL 1-20
Macroscopic Supramolecular Assembly of Hydrogels Based on
Host/Guest Polymer Brushes
Yawen Xu, Yang Zhou, Jing Chen*, Jun Fu*
(Ningbo Institute of Materials Technology & Engineering, Chinese Academy of Sciences, 1219
Zhongguan West Road, Ningbo 315201, China.)
*E-mail: [email protected] or [email protected]
As the most human-made materials to biological systems, hydrogels have been
employed to manufacture multifunctional smart device [1-3]. The network of hydrogels
is commonly isotropic, however, which is substantially differentiated from the
well-defined anisotropic structure of most biological systems. Inspired by the
integrated circuit which achieves its function by assembling dissimilar components
organically together, an emerging philosophy in building anisotropic hydrogels is
macroscopic assembly [4]. Unfortunately, current achievements are empirical, to some
extent, on the interfacial interactions, being short of a highly controllable way to
precisely tailor the content, distribution and freedom of motion of surface
supramolecular groups. The macroscopic supramolecular assembly is thereby still in a
dilemma to be widely used due to its deficient reliability, controllability and flexibility
for fabricating sophisticated devices. In this presentation, we will present an approach
to meet the challenge. Polymer brushes containing complementary host
(β-cyclodextrin)/guest (adamantane) groups are separately in-situ grafted from
surfaces of two hydrogel blocks via surface-initiated atom transfer radical
polymerization (SI-ATRP), leading to a stable macroscopic supramolecular assembly.
This assembling strategy not only improves the binding reliability independent of the
nature of assembling units, but also flexibly tunes the interfacial supramolecular
interaction by adjusting the chain length or host/guest content of brushes, which will
open a new door to manufacture multi-functional and multi-material assemblies in a
wide field of applications.
Keywords: Macroscopic supramolecular assembly, Hydrogel, Polymer brushes
References:
[1]. H. R. Lee, C. C. Kim, J. Y. Sun, Advanced Materials 2018, 30, e1704403.
[2]. H. Wang, C. N. Zhu, H. Zeng, X. Ji, T. Xie, X. Yan, Z. L. Wu, F. Huang,
Advanced Materials 2019, 0, 1807328.
[3]. T. Shay, O. D. Velev, M. D. Dickey, Soft matter 2018, 14, 3296-3303.
[4]. C. Ma, T. Li, Q. Zhao, X. Yang, J. Wu, Y. Luo, T. Xie, Advanced Materials
2014, 26, 5665-5669.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
58
OL 1-21
Natural Triterpenoid-Tailored Phosphate: In Situ Reduction of
Heavy Metals Spontaneously to Generate Electrochemical Hybrid
Gels
Yuxia Gao1, Fengpei Du1, Jun Hu2§§§§§§
(1Department of Applied Chemistry, China Agricultural University, Beijing 100193, China; 2Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University
of Chemical Technology, Beijing 100029, China)
*E-mail: [email protected]
Hydrogels, consisting of three-dimensional networks formed by molecular
self-assembly to encapsulate water, have attracted much attention for a wide range of
potential applications, especially in conductive materials. In this work we have
designed and synthesized a natural triterpenoid-tailored phosphate (MGP), and this
amphiphilic MGP could form stable hydrogel and extract gold salt from water,
followed by spontaneous in situ Au nanoparticles (AuNPs) formation without external
reductants. Notably, the AuNPs were mainly localized on gel fibers rather than in
solvent pockets, and the resulting MGP-AuNPs hybrid gel exhibited attractive
electrocatalytic and conductive properties. In addition, as an efficient leaching
extraction agent, MGP hydrogel showed higher affinity towards heavy metals over
other common metals on account of the high reduction potential of heavy metals. This
work not only provides a novel yet simple way in generating electrochemical hybrid
gels by in situ reduction of heavy metals spontaneously, but also expands the
application of nature product-based functional materials.
Keywords: Gel, Triterpenoid, Nanoparticles, Electrochemistry, Self-assembly
References:
[1]. Gao YX.; Hao J.; Yan Q.*; Du FP.; Ju Y.; Hu J.*, ACS Appl. Mater. Interfaces
2018, 10, 17352.
[2] Gao YX.; Hao J.; Liu JG.; Liang Y.; Du FP.; Hu J.*; Ju Y*, Mater. Chem. Front.
2019, 3, 308.
This research was supported by the National Natural Science Foundation of China (Grant No.
21802166) and Chinese Universities Scientific Fund (2019TC013, 2019TC109).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
59
OL 1-22
High-strength and Self-Healing Hydrogel Based on
Carboxymethylcellulose
Nan Li 1, Wei Chen 1*
(1 College of Engineering, Qufu Normal University, Rizhao, 276826, China)
*E-mail: [email protected]
Hydrogels are the focus of extensive research due to their potential applications
in various fields including tissue engineering, drug delivery, soft actuators, and
sensors, etc. However, insufficient functionality and weak mechanical properties limit
their practical utilities. Herein, we developed a simple approach to fabricate strong,
tough, and self-healable hydrogel by introducing CMC into poly (acrylic acid)
(PAA)-Fe3+ hydrogel as well as by simply soaking the gel in sodium chloride
solution. The synergetic interactions of -COO-/Fe3+ physically ionic network as well
as PAA covalent network can homogeneously distribute stress, and more importantly,
a high degree of network density, and chain entanglement introduced by soaking
treatment could act as “sacrificial bonds” to dissipate energy effectively.
Additionally, the noncovalent ionic interactions serve as dynamic but stable
associations, leading to the effective self-healing efficiency over 90 % after damage.
We expect that this facile strategy by integrating the biocompatible and biodegradable
CMC and then soaking in NaCl solution may enrich the avenue in exploration of
high-strength, toughness and self-healing cellulosic hydrogels to expand their
potential applications in various fields.
Keywords: Carboxymethylcellulose, DN Hydrogels, Self-healing, High mechanical
properties
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
60
OL 1-23
Ultrastiff and Tough Supramolecular Hydrogels with a Dense and
Robust Hydrogen Bond Network
Yan Jie Wang1, 2, Li Chen2, 3, Zi Liang Wu1*, Qiang Zheng1
(1Ministry of Education Key Laboratory of Macromolecular Synthesis and Functionalization,
Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China; 2State Key Laboratory of Separation Membranes and Membrane Processes, School of Materials
Science and Engineering, Tianjin Polytechnic University, Tianjin 300387, China; 3School of
Materials Science and Engineering, Tianjin University of Technology, Tianjin 300384, China)
*E-mail: [email protected].
Synthetic tough gels are usually much softer than some biotissues (e.g., skins
with modulus up to 100 MPa). Here we report a new class of ultrastiff and tough
supramolecular hydrogels facilely prepared by copolymerization of methacrylic acid
and methacrylamide. The gels with water content of approximately 50−70 wt %
possessed remarkable mechanical properties, with Young’s modulus of 2.3−217.3
MPa, tensile breaking stress of 1.2−8.3 MPa, breaking strain of 200−620%, and
tearing fracture energy of 2.9−23.5 kJ/m2, superior to most existing hydrogels,
especially in terms of modulus. Typical yielding and crazing were observed in the gel
under tensile loading, indicating the forced elastic deformation of these hydrogels in a
glassy state, as confirmed by dynamic mechanical analysis. The ultrahigh stiffness
was attributed to the dense cross-linking and reduced segmental mobility caused by
the robust intra- and interchain hydrogen bonds. Because of the dynamic nature of
noncovalent bonds, these gels also showed rate-dependent mechanical performances
along with good shape memory and recyclability. This strategy should be applicable
for other systems toward robust mechanical properties, versatile functionalities, and
promising applications of hydrogel materials as structural elements.
Keywords: Supramolecular gels, High stiffness, Yielding, Hydrogen bonds,
Recyclability
References:
[1]. Wang YJ#.; Zhang XN#.; Song Y.; Zhao Y.; Chen L.; Su F.; Li L.; Wu ZL*;
Zheng Q, Chem. Mater. 2019, 31,1430
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
61
OL 1-24
Alginate-based hydrogel microcapsules for immobilized biocatalysis
Xiudong Liu1,*, Huijing Li1, Xiaojun Ma2
(1College of Environment and Chemical Engineering,Dalian University, Dalian 116622, China; 2Dalian Institute of Chemical Physics,Chinese Academy of Sciences, Dalian 116023, China.)
*E-mail: [email protected]
Biocatalysis techniques have been widely applied in industrial biotechnology and
substituted some traditional chemical synthetic routes regarding to the high selectivity,
mild and environment benign condition. However, it is still a challenge to maintain
the activity and stability of biocatalysts in hostile environment. Immobilization of
biocatalysts in carriers is an industrial potential technology to solve the above
problem and has been studied with many materials.
Alginate is a biocompatible polysaccaride, which can transform from sol into
hydrogel under divalent cations. Based on our specialty in hydrogel microcapsule
technology and cell culture, alginate-chitosan (AC) hydrogel microcapsules were
prepared as immobilization carrier by emulsification-internal gelation and
complexation reaction. Yeast cells with biotransformation ability were immobilized in
AC microcapsules, and studied on the cell growth and metabolism properties in the
culture medium-solvent two phase systems. AC microencapsulated yeast cells can
keep activity and grow without adverse effect by two phase systems. Meantime, the
product concentration (aromatic alcohol) can reach above 5 g/L with substrate
concentration of 8-16 g/L, which was almost two-fold than that by free yeast cells.
Keywords: Alginate, Chitosan, Hydrogel microcapsule, Immobilized biocatalysis
References:
[1]. Eş, I.; Vieira JDG.; Amaral AC., Applied Microbiology and Biotechnology,
2015, 99(5), 2065-2082.
[2]. Yu WT.; Song HY.; Zheng GS.; Liu XD.; Zhang Y.; Ma XJ., Journal of
Membrane Science, 2011, 377, 214-220.
[3]. Song HY.; Yu WT.; Liu XD.; Ma XJ., Carbohydrate Polymers, 2014, 108,
10-16. This research was supported by the National Natural Science Foundation of China (Grant No.
21276033), and the Liaoning Provincial BaiQianWan Talents Program (No. 2017-6).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
62
OL 2-1
Natural triterpene-tailored supramolecular gels: chiral transfer and
amplification
Jun Hu1*******, Yuxia Gao2, Hao Zhang1, Yong Ju3
(1Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing
University of Chemical Technology, Beijing 100029, China; 2Department of Applied Chemistry,
China Agricultural University, Beijing 100193, China; 3Department of Chemistry, Tsinghua
University, Beijing 100084, China)
*E-mail: [email protected]
Triterpenes, naturally occurring compounds, have attracted increased attention in
field of supramolecular gels due to their rigid skeletons, multiple functional groups,
and unique stacking manners. Nevertheless, little research has been devoted to their
macroscopic chiral structures. To explore a strategy to realize the chirality translation
from molecules to nano/macro-scale using triterpenes as building blocks, we have
synthesized a series of pyridinium-contained triterpene amphiphiles. By adjusting the
linker length and the solvent composition, well-ordered helical ribbons with both
right- and left-handedness have been fabricated in a cooperative supramolecular
polymerization manner. Additionally, driven by electrostatic interactions between
pyridinium and silica precursor, the supramolecular chirality was successfully
imprinted onto the silica nanostructures using the gel-sol mineralization process. This
work illustrates a facile methodology for creating supramolecular chiral
nanostructures that originate from natural chiral products.
Keywords: Triterpene, Gel, Supramolecular chirality
References:
[1]. Gao Y.; Hao J.; Wu J.; Zhang X.; Hu J.*; Ju Y*, Nanoscale 2015, 7, 13568.
[2]. Gao Y.; Hao J.; Yan Q.; Du F.; Ju Y.; Hu J*, ACS Appl. Mater. Interfaces 2018,
10, 17352.
[3]. Gao Y.; Hao J.; Liu J.; Liang Y.; Du F.; Hu J.*; Ju Y*, Mater. Chem. Front. 2019,
3, 308.
This research was supported by the National Natural Science Foundation of China (Grant No.
21604085) and National Key R&D Program of China (Grant No. 2017YFD0200302).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
63
OL 2-2
The “Morse Code” between Solvent Polarity and Morphology
Flexibility
Si Chen, Tianyu Shan, Xu Wang*
(College of Materials Science and Engineering, Zhejiang University of Technology, Hangzhou
310014, China.)
*E-mail: [email protected]
LC physical gels are a new class of dynamically functional materials consisting
of LCs and fibrous aggregates of molecules that are called ‘‘gelators’’, exhibiting
induced or enhanced electro-optical, photochemical, and electronic properties[1].
Phase-separated structures are formed in LC physical gels by the combination of two
components, which can further affect it’s photoelectric performance due to the change
of interface action on the boundary regions. Hence the regulation of various
morphologies of LC gel is crucial.
Nevertheless, researches based on solvents-induced morphology are always
focused on common solvents rather than the LCs, which may due to LCs’ unaware
solvent parameters. Herein, by measuring solvent polarity of LCs and quantitatively
comparing fiber flexibility, we connect solvent polarity with morphology flexibility
by a fitting function, which can even be generalized to common solvents. Besides,
additional coarse-grained molecular dynamics simulations unexceptionably support
our theory that the solvent polarity is just like the “morse code”, and the “morse code”
can be decoded as morphology flexibility by the fitting function we built. We hope it
could be a quick way to judge morphology flexibility before troublesome electron
microscope in supramolecular systems.
Keywords: Supramolecular chemistry, Self-assembly, Nanostructures, Solvent
polarity, Molecular simulation
References:
[1] Kuang GC.; Ji Y.; Jia XR.; Chen EQ.; Gao M.; Yeh JM.; Wei Y*, Chem. Mater.
2009, 21, 456
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
64
OL 2-3
Hierarchical Macroporous networks construct by Supramolecular
chiral self-assembly of POSS core dendrimers
Huiwen He1, Hao Zheng1, Si Chen1*, Xu Wang1*
(1College of Materials Science and Engineering, Zhejiang University of Technology, Hangzhou
310014, China. )
*E-mail: [email protected], [email protected].
The accurately construction of supramolecular gel with well-defined nano
structures, size, and functions through supramolecular self-assembly has received
considerable attention over the past few decades. Macroporous materials which
contain ordered macroporous structure with pore size of 50 nm–5 μm are useful for
applications in catalysts, thermal insulation materials, electromagnetic shielding
material, photonic band gap materials, optoelectronic devices, microreactors, and
tissue engineering scaffolds. However, the formation of macroporous structures by
supramolecular self-assembly method remains a great challenge due to the difficulty
in controlled self-assembly for ordered hierarchical nanostructures which only rings
and toroids can be easily obtained. Herein we report the controlled formation of
macroporous “loofah-like” nano-structures from dendrimer organogelators with POSS
as the core and eight amino acids as the peripheral arms by precisely regulation of the
supramolecular chiral self-assembly. Through regulating the chemical structure of the
peripheral amino acids of dendrimer or the ee value of the two-component assembly
system, ordered fiber bundles, micro-rings, helix fibers, and hierarchical macroporous
“loofah-like” network structures can be accurately obtained. This approach
innovatively provides a method for constructing macroporous materials by using
hierarchical supramolecular chiral self-assembly of POSS based dendrimers.
Keywords: Gel, Macroporous, Dendrimer, POSS, Supramolecular Chiral
References:
[1] S. S. Babu, S. Mahesh, K. K. Kartha and A. Ajayaghosh. Chem Asian J, 2009, 4: 824-829.
[2] G. Tang, S. Chen, F. Ye, X. Xu, J. Fang and X. Wang. Chem. Commun., 2014, 50: 7180-7183.
[3] H. He, S. Chen, X. Tong, Y. Chen, B. Wu, M. Ma, X. Wang and X. Wang. Soft Matter, 2016,
12: 957-964.
[4] H. He, S. Chen, X. Tong, Z. An, M. Ma, X. Wang and X. Wang. Langmuir, 2017, 33:
13332-13342.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
65
OL 3-1
Nanocellulose Based Bio-scaffold Routed For Biomedical
Applications
Arun Saini,Bai-Liang Xue, Xin-ping Li*
College of Bioresources Chemical and Materials Engineering,
Shaanxi University of Science and Technology, Xi’an 710021, Shaanxi, China
*Corresponding author, E-mail: [email protected], Tel.:029-86168236
An innovative approach towards material unification for advanced bio-applications
has been proposed here. Wholly cellulose based bio-scaffolds were developed by a
simple and green method as a durable antibacterial dressing. 3-D Bio-scaffolds,
reinforced with carboxylated cellulose nanocrystals (cCNCs) were prepared by simple
freeze-drying process using microfibrillated cellulose (MFC) as matrix. Natural
bio-extract (i.e. Cinnamomum cassia) was used as bio-solvent and was amalgamated
with the base cellulosic components to promote the bioactivity of 3-D Bio-scaffolds.
The optimum hydrophilic and hydrophobic balance in the prepared scaffolds have
improved their swelling characteristics with maintained structural stability in
water-based medium. The use of cCNCs can play an important role in improving their
mechanical and thermal properties. Additionally, the use of Cinnamon cassia can
supplement the scaffolds with efficient antibacterial activity required for their usage
as wound dressing materials. Further, due to the inherent flexibility exhibited by the
base MFC matrix, the prepared scaffolds have demonstrated a flexible behavior that is
considered beneficial in promoting cell adhesion activities. Initial investigations
related to the material formulation paves a way towards exploring these scaffolds as
an antibacterial wound dressing material.
Keywords: Microfibrillated cellulose; carboxylated CNCs; bio-extract; antibacterial
activity; biocompatibility.
References:
[1] Yadav C., MajiPK., Carbohyd. Polym.2018, 203, 396.
[2] Cheng, H.; Li, C.; Jiang, Y.; Wang, B.; Wang, F.; Mao, Z.; Xu, H.; Wang, L.; Sui,
X. J. Mater. Chem. B.2018, 6, 634.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
66
OL 3-2
Controlled Self-Assembly of MXene-Polymer at Liquid/Liquid
Interfaces
Shaowei Shi1†††††††, Bingqing Qian1, Xinyu Wu1, Hao-Bin Zhang1, Thomas P.
Russell1,2
(1Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing
University of Chemical Technology, Beijing 100029, China. 2Polymer Science and Engineering
Department, University of Massachusetts, Amherst, Massachusetts 01003, USA.)
*E-mail: [email protected]
A new two-dimensional (2D) transitional metal carbide/nitride, MXene, has
become increasingly attractive for many potential applications such as energy storage,
sensors and electromagnetic interference shielding owing to its rich surface chemistry
and outstanding conductivity. However, assembly strategies of MXene to construce
macroscopic-scale functional assemblies, especially three-dimensional (3D) porous
materials, are very limited and challenging. In this work, based on liquid-liquid
interfaces, we developed a new janus-like MXene-surfactant by taking advantage of
the cooperative assembly of MXene and end-functionalized polymer ligand at the
water/oil interfaces, and realize the controlled self-assembly of MXene at water/oil
interfaces and the preparation of stable Pickering emulsions by regulating the
interactions between MXene ans polymer ligand. After that, using the Pickering
emulsions as templates, 3D porous materials of MXene were constructed with a
down-top approach. It is anticipated that this project will provide theoretical guidance
and technical support for the preparation of high performance macroscopic-scale
MXene assemblies and polymer nanocomposites,which is of great scientific
significance.
Keywords: MXene, Liquid-liquid interfaces, Nanoparticle-surfactant, Porous
materials
References:
[1]. Li Y.; Liu X.; Zhang Z.; Zhao S.; Tian G.; Zheng J.; Wang D.; Shi S.* Russell T.
P.*, Angew. Chem. 2018, 130, 13748-13752
This research was supported by the Beijing Natural Science Foundation (Grant No. 2194083).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
67
OL 3-3
“Stiff-Soft” Binary Synergistic Aerogels with Superflexibility and
High Thermal Insulation Performance
Junyan Zhang1, Yanhua Cheng1*, Mike Tebyetekerwa1, Si Meng1, Meifang Zhu1*
,
Yunfeng Lu2
(1State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of
Materials Science and Engineering, Donghua University, Shanghai, 201620, China; 2 Department
of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095,
USA.)
*E-mail: [email protected]
Designing aerogel materials featuring both high thermal insulation property and
excellent mechanical robustness is of great interest for applications in superior
integrated energy management systems.[1] To meet the above requirements, we report
composite aerogels based on hierarchical “stiff-soft” binary networks, in which
secondary mesoporous polymethylsilsesquioxane domains intertwined by bacterial
cellulose nanofibrillar networks are connected in tandem. The resulting composite
aerogels are characterized by highly porous (93.6%) and nanosized structure with a
surface area of 660 m2 g-1, leading to the excellent thermal insulation performance
with a low thermal conductivity of 15.3 mW m-1 K-1. The integrated “stiff-soft” binary
nature also endow the composite aerogels with high flexibility that can conform to
various substrates as well as large tensile strength that can withstand more than 2.70 ×
104 times its own weight. These composite aerogels show multifunctionality in terms
of efficient wearable protection, controllable thermal management and ultrafast
oil/water separation. These favorable multi-features present composite aerogels ideal
for aerospace, industrial and commercial applications.
Keywords: composite aerogels, nanofibrils, superflexibility, high thermal insulation,
hydrophobicity
References:
[1]. P. C. Hsu; A. Y. Song; P. B. Catrysse; C. Liu; Y. C. Peng; J. Xie; S. H. Fan; Y.
Cui*, Science 2016, 353, 1019
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
68
OL 3-4
Highly Porous Polymer Aerogel Film - Based Triboelectric
Nanogenerators
Qifeng Zheng1, Liming Fang2*, Haiquan Guo3, Kefang Yang1, Zhiyong Cai4, Mary
Ann B. Meador3, Shaoqin Gong1
(1Department of Material Science and Engineering, University of Wisconsin-Madison, Madison,
WI 53706, USA; 2School of Materials Science and Engineering, South China University of
Technology, Guangzhou 510641, China; 3Ohio Aerospace Institute, Brookpark, OH 44142, USA; 4Forest Products Laboratory, USDA, Madison, WI 53726, USA)
*E-mail: [email protected]
A novel class of high performance polymer porous aerogel film-based
triboelectric nanogenerators (A-NGs) is demonstrated. The A-NGs, made of a pair of
highly porous polymer films, exhibit much higher triboelectric outputs than the
corresponding dense polymer film-based triboelectric nanogenerators (D-NGs) under
the same mechanical stress. The triboelectric outputs of the A-NGs increase
significantly with increasing porosity, which can be attributed to the increase in
contact area and the electrostatic induction in the porous structure, thereby leading to
additional charges on the porous surface. Remarkably, the A-NG fabricated using
porous chitosan aerogel film paired with the most porous polyimide (with a porosity
of 92%) aerogel film demonstrates a very high voltage of 60.6 V and current of 7.7
µA, corresponding to a power density of 2.33 W m-2, which is sufficient to power 22
blue light-emitting-diodes (LEDs). This is the first report on triboelectric
nanogenerators (TENGs) employing porous polymer aerogel films as both positive
and negative materials to enhance triboelectric outputs. Furthermore, enhancing the
tribopositive polarity of the cellulose aerogel film via silanization using aminosilane
can dramatically improve the triboelectric performance. Therefore, this study provides
new insights into investigating porous materials with tunable triboelectric polarities
for high performance TENGs.
Keywords: energy harvesting; porous polymer films; triboelectric nanogenerators
References:
[1]. Zheng, Q.#, Fang, L.#, Guo, H., Yang, K., Cai, Z., Meador, M. A. B., Gong, S.*,
Adv. Funct. Mater. 2018, 28, 1706365.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
69
OL 3-5
Graphene-crosslinked CNT aerogel for the preparation of elastic
porous polymer composites
Fei Zhang, Zhi Xing Zhang, Wei Feng
(School of Materials Science and Engineering, Tianjin University, Tianjin Key Laboratory of
Composite and Functional Materials, Tianjin 300072, P.R China.)
E-mail: [email protected]
The controllability in thermal/electrical conductivity is significant for application
in flexible strain-related device.[1] Due to the strength-elasticity
(compressibility/resilience) trade-off, the preparation of high-strength and elastic
polymer composites with controllable thermal and electrical conductivity is full of
challenges. In this work, we reported a novel approach to prepare three-dimensional
(3D) porous graphene-crosslinked CNT/polyimide nanocomposite with
stress-controllable thermal and electrical conductivity by constructing a 3D hybrid
carbon aerogel as template and conductive network. We first constructed a continuous
3D graphene-welded CNT (Gw-CNT) hybrid architecture as the continuous
conductive network and the elastic template for polyimide. In the process of preparing
Gw-CNT/polyimide composites, polyimide was coated on the surface of carbon
skeleton layer by layer to obtain uniform composites with different micro-pore
structures, which is the key to realize the controllable elasticity of composites. The
resulting monoliths inherit the properties of polyimide and nano-carbon material
(graphene and CNT), with fine high temperature resistance (>500 ˚C), excellent
thermal (~10.89 W m-1 K-1) and electrical conductivity (~0.29 S m-1). And its
stress-controllable thermal and electrical conductivity makes the Gw-CNT/polyimide
composite can be an important candidate material for piezoresistive sensors.
Keywords: Graphene/CNT aerogel, polymer composites, Porosity, Thermally
conductivity, Electrical conductivity
References:
[1]. Zhang F.; Feng Y.; Qin M.; Ji T.; Lv F.; Li Z.; Gao L.; Long P.; Feng W*,
Carbon, 2019, 145: 378.
This research was supported by the National Natural Science Foundation of China (Grant No.
51573125).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
70
OL 3-6
The Organic Acids Assisted Sol-Gel Method for Preparing Functional
Aerogels
Xiaoqing Wang, Mingjia Zhi* and Zhanglian Hong*
(State Key Laboratory of Silicon Materials, School of Materials Science and Engineering,
Zhejiang University, Hangzhou 310027, China.)
*E-mail: [email protected]; [email protected].
Here I am presenting a new class of gelators based on the low-cost organic acids
and the corresponding functional aerogels prepared from such gelators. A series of
organic acids such as citric acid, L-aspartic acid, DL-Mercaptosuccinic acid and
etidronic acid were adopted to initiate the sol to gel transition in the solution phase 1, 2,
3, 4. After supercritical drying, metal oxide, metal sulfide and metal phosphate aerogels
can be obtained with the characteristics similar with those of the conventional metal
oxide aerogels prepared by epoxide adding method. The composition of the final
aerogel can be readily tuned by choosing the organic acids with different functional
groups in the side chains. The detail gelation mechanism was analyzed by using
several different organic acids containing identical main chain but different side
groups. It is found that the complex interactions including covalent bond and
coordination bond interactions between organic acids and metal ions are vital to give
rigid gel network. Further modification of the aerogels included tuning the
mesoporous structure, compositing them with conductive graphene and carbon
nanotubes, and loading noble metal nanoparticles (Pt, Au etc). These results
demonstrated that these functional aerogels are good candidates for energy storage,
electrochemical H2 and O2 evolution catalyst and thermal insulation applications.
Keywords: Organic acid, Sol-gel, Aerogel, Gelator
References:
[1]. Wang XQ.; Li CY.; Shi ZY.; Zhi MJ.*; Hong ZL.*, RSC Advances 2018, 8,
8011-8020.
[2]. Wang XQ.; Wu ZX.; Zhi MJ.*; Hong ZL.*, J. Sol-Gel Sci. Techn. 2018, 87,
734-742.
[3]. Gao QY.; Wang XQ.; Shi ZY.; Ye ZR.; Wang WC.; Zhang N.; Hong ZL.*; Zhi
MJ.*, Chem. Eng. J. 2018, 331, 185-193.
[4]. Zhang Z.; Gao Q.; Liu Y.;Zhou C.;Zhi MJ.*; Hong ZL.*; Zhang F.; Liu B., RSC
Advances 2015, 5, 84280-84283.
This work is supported by National key research and development program (Grant No.
2016YFB0901600), Zhejiang Provincial Natural Science Foundation of China under
Grant No. LY19E020014, and NSCF (Grant No. 21303162 and Grant No. 11604295.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
71
OL 3-7
Mesoporous Silica Nanoparticles as Nanocarriers for Controlled
Pesticide Release
Dr. Lidong Cao, Chunli Xu, Muhammad Bilal, and Qiliang Huang*
Key Laboratory of Integrated Pest Management in Crops, Ministry of Agriculture, Institute of
Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, China
Pesticides are widely used to improve the crop yield to meet the food demand of
the escalating global population and ensure sustainable development of modern
agriculture. However, depending on the methods of application and climatic conditions,
more than 90% of the applied pesticides are either lost in the environment or unable to
reach the target organisms, which not only increases the cost of treatment but also
produce undesirable side effect on the environment. With the rapid development of
nanoscience and nanotechnology in recent years, smart nano-delivery systems of
pesticides, which deliver the active ingredients slowly and sustainedly for longer
durations to a specified target sites at a desired rate, seem promising and have great
potential to address the current challenges that modern pesticides face. Since the
discovery of Mobil Crystalline Material 41 (MCM-41), research on and development
of mesoporous silica nanoparticles (MSNs) has gained worldwide interest due to
MSNs’ unique properties. In the present study, pesticides-loaded various
functionalized MSNs have been prepared, and the release profiles of cargo molecule as
well as the translocation, distribution and degradation behaviors of the target pesticide
in cucumber plants have been investigated. Moreover, the good bioactivity on target
plant without adverse effects on the growth of nontarget plant was also explored.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
72
OL 4-1
Achieving Fracture-resistant Composite Hydrogels by Large
Energy-dissipative Process Zones
Yiwan Huang,a Daniel R. King,a,b Wei Cui,c Tao Lin Sun,a,b Honglei Guo,a,b Takayuki
Kurokawa,a,b Hugh R. Brown,e Chung-Yuen Hui,f Jian Ping Gong a,b,d
(a Faculty of Advanced Life Science, b Soft Matter GI-CoRE, c Graduate School of Life Science, d Institute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University,
Sapporo 001-0021, Japan; e ARC Centre of Excellence for Electromaterials Science and Australian Institute for Innovative Materials, University of Wollongong, NSW, 2522, Australia; f
Department of Mechanical and Aerospace Engineering, Cornell University, NY 14853, USA)
E-mail address: [email protected]
Fiber reinforced soft composites (FRSCs) have been developed recently by
combining tough but soft polyampholyte (PA) hydrogels with stiff yet flexible woven
glass fabrics.[1,2] In this work, we find that the soft composites show increased tearing
resistance with sample size and achieve size-independent, exceptionally high tearing
energy above a specific size on the centimeter scale. Such size-dependent tearing
behavior correlates with the failure mode change from fiber pull-out to fiber fracture.
These results demonstrate that the rigid fibers in the soft matrices transmit force over
a large distance, giving the composites very large process zones. Tremendous energy
is dissipated in the large process zones, resulting in the superior fracture resistance of
FRSCs. By saturation of the process zone size, the soft composites become
extraordinarily tough, showing an intrinsic tearing energy of ~1000 kJ m−2 that
outperforms other existing tough materials. These novel FRSC materials from
hydrated biocompatible hydrogels fill the gap between soft materials and traditional
rigid materials, as demonstrated by their high tensile modulus (several GPa) and
strength (> 300 MPa), along with exceptionally high tearing toughness (Fig. 1).[3]
Keywords: fiber reinforced hydrogels, super tough hydrogels, material failure modes,
energy-dissipative process zone, fracture model
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
73
Fig. 1. Fracture energy versus Young’s modulus map of materials. Our PA hydrogel composites
show superior fracture resistance.
References:
[1] D. R. King, T. L. Sun, Y. Huang, T. Kurokawa, T. Nonoyama, A. J. Crosby and J. P.
Gong, Mater. Horiz., 2015, 2(6): 584-591.
[2] Y. Huang, D. R. King, T. L. Sun, T. Nonoyama, T. Kurokawa, T. Nakajima and J. P.
Gong, Adv. Funct. Mater., 2017, 27(9): 1605350.
[3] Y. Huang, D. R. King, W. Cui, T. L. Sun, H. Guo, T. Kurokawa, H. R. Brown, C. Y.
Hui, J. P. Gong, J. Mater. Chem. A, 2019, published online, DOI:
10.1039/C9TA02326G.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
74
OL 4-2
Bio-inspired hydrogel/organogel materials with special adhesion
Xi Yao1*, Junjie Liu2,3, Canhui Yang3, and Lie Chen4
(1Key Laboratory for Special Functional Materials, Ministry of Education, Henan University,
Kaifeng, Henan 475000; 2Department of Engineering Mechanics, Zhejiang University, Hangzhou,
Zhejiang, 310027; 3School of Applied and Engineering Sciences, Harvard University, Cambridge,
Massachusetts, 02138, USA; 4Beijing University, Beijing 100190)
*E-mail: [email protected]
Gel material, empowered by functions from both polymer networks and solvents,
enjoys significant applications in industry, medicine, daily life and scientific research.
However, it has not received much attention regarding to the technology development
of hydrogel coatings and the key scientific points within. In the past few years, we
have carried out research works based on hydrogel coating mechanics as well as
coating functionalization by super-wettability and special high/low adhesion,
anticipating applications in petroleum transport, microfluidics, anti-icing/de-icing,
medical devices, controlled drug release, etc.
Keywords: Hydrogel, Organogel, Wettability, Coating, Adhesion
References:
[1] Xi Yao, Lie Chen, Jie Ju, Changhua Li, Ye Tian, Mingjie Liu* and Lei Jiang,
Advanced Materials, 2016, 34, 7383–7389
[2] Xi Yao, Shuwang Wu, Lie Chen, Jie Ju, Zhandong Gu Mingjie Liu, Jianjun
Wang,* and Lei Jiang, Angewandte Chemie Internation Edition, 2015, 54, 8975
–8979
[3] Xi Yao, Jie Ju, Shuai Yang, Jianjun Wang*, Lei Jiang, Advanced Materials, 2014,
26, 1895-1900
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
75
OL 4-3
Mussel-Inspired Cellulose Nanocomposite Tough Hydrogels with
Synergistic Self-Healing, Adhesive, and Strain-Sensitive Properties
Changyou Shao, Lei Meng, Jun Yang*
(China. Beijing Key Laboratory of Lignocellulosic Chemistry, Beijing Forestry University, No 35,
Tsinghua East Road, Haidian, Beijing,100083, China)
*E-mail: [email protected]
The remarkable progress in efforts to prepare conductive self-healing hydrogels
mimicking human skin’s functions has been witnessed in recent years. However, it
remains a great challenge to develop an integrated conductive gel combining excellent
self-healing and mechanical properties, which is derived from their inherent
compromise between the dynamic cross-links for healing and steady cross-links for
mechanical strength. In this work, we design a tough, self-healing, and self-adhesive
ionic gel by constructing synergistic multiple coordination bonds among tannic
acid-coated cellulose nanocrystals (TA@CNCs), poly(acrylic acid)chains, and metal
ions in a covalent polymer network. The incorporated TA@CNC acts as a dynamic
connected bridge in the hierarchically porous network mediated by multiple
coordination bonds, endowing the ionic gels the superior mechanical performance.
Reversible nature of dynamic coordination interactions leads to excellent recovery
property as well as reliable mechanical and electrical self-healing property without
any assistance of external stimuli. Intriguingly, the ionic gels display durable and
repeatable adhesiveness ascribed to the presence of catechol groups from the
incorporated tannic acid, which can be adhered directly on human skin without
inflammatory response and residual. Additionally, the ionic gels with a great strain
sensitivity can be employed as flexible strain sensors to monitor and distinguish both
large motions (e.g., joints bending) and subtle motions (e.g., pulse and breath), which
enable us to analyze the data on the user interface of smart phone via programmable
wireless transmission. This work provides a new prospect for the design of the
biocompatible cellulose-based hydrogels with stretchable, self-adhesive, self-healing,
and strain-sensitive properties for potential applications in wearable electronic sensors
and healthcare monitoring.
Keywords: Hydrogel, Self-healing, Adhesive, Tough, Strain sensor
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
76
OL 4-4
Hollow hydrogel networks for temperature-controlled water fluidics
Qing Chen, Lidong Zhang‡‡‡‡‡‡‡
Department of Chemistry and Molecular Engineering, East China Normal University, Shanghai,
200241, People’s Republic of China
E-mail:[email protected]
ORCID Lidong Zhang: 0000-0002-0501-6162
Fabrication of multiply branched hollow hydrogel tubes (HTs) is still a challenge, and
an effective method is not available yet. We herein develop a cost-effective, facile
method for synthesis of multiply branched hollow HTs by direct conversion of
single-layer sodium alginate (SA) films to HTs in aqueous solution. The process does
not require special conditions, and HTs of arbitrary morphology and connectivity can
be prepared in a couple of minutes. The method provides access to branched HTs and
HT nets and grids of arbitrary shape and topology without the necessity to use
templates or molds. The wall of branched HTs can be functionalized to satisfy various
application requirements, which are demonstrated by controlled fluidics at high and
low temperatures, respectively. We also demonstrate that the hollow branched HTs
can be used as templates for preparation of other tubular networks with improved
mechanical properties.
Keywords: Sodium alginate, Hollow hydrogel network, Temperature-controlled
water fluidics, Hydrogel actuators
References:
[1]. Chen, Q.; Liang, S.; Zhang, L*, Chem. Commun. 2018, 54, 10304
[2]. Zhang, L*. et al. Adv. Mater., 2017, 29, 1702231.
[3]. Zhang, L, et al. Nat. Commun., 2015, 6:7429, 1-8.
[4]. Zhang, L.et al. Adv. Funct. Mater., 2016, 26, 1040-1053.
[5]. Zhang, L. et al. Angew. Chem. In. Ed., 2015, 54, 8642-8647.
[6]. Wei, J.; Wang, S.; Zhang, L*, ACS Appl. Mater. Interfaces, 2018, 10,
29161–29168
This research was supported by the National Natural Science Foundation of China (Grant No.
51603068).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
77
OL 4-5
Deswelling behavior of pNIPAM composite gel consisting of
nanosheet liquid crystal whose orientation is controlled by
asymmetric electric field
Takumi Inadomi and Miyamoto Nobuyoshi*
(Department of Life, Environment and Materials Science, Fukuoka Institute of Technology,
3-30-1 Wajiro-higashi, Higashi-ku, Fukuoka, 811-0295, Japan)
*E-mail: [email protected]
We have recently reported
composite gels in which inorganic
nanosheet liquid crystals (LCs) are
aligned along two axes [1]. Here, we
report the composite gels with
asymmetrically and anisotropically
oriented nanosheet LCs. The
pre-polymerization solution was
prepared by adding
N-isopropylacrylamide (NIPAM) as a
monomer, a crosslinking agent, and a
photopolymerization initiator to an
aqueous nanosheet dispersion.
Alternating current electric field was
applied to the solution for 180 minutes using the point-to-line electrodes, followed by the
pre-polymerization solution was irradiated with ultraviolet light to proceed
photopolymerization. As shown in Fig. 1, nanosheets are oriented asymmetrically along
the fan-like electric flux line. The cross-sectional images show that the nanosheets are
separated into upper isotropic phase and lower LC phase. The volume fraction of the LC
phase was larger at the points with larger electric field, that is near the line electrode than
the point one. Because the configuration of the electrode is easily modifiable, the
composite gels with variety of embedded structure were further obtained. The present
gels show thermally-induced volume phase transition which is characteristic of pNIPA;
the composite gel exhibited characteristic bending behaviors depending on the
asymmetric and anisotropic structure.
Keywords: Nanocomposite gel, Inorganic nanosheet liquid crystal, Electric field
References:
[1]. T. Inadomi.; S. Ikeda.; Y. Okumura.; H. Kikuchi.; N. Miyamoto , Macromol. Rapid Commun.
2014, 35, 1741-1746.
Fig. 1. Polarized microscope image and schematic view of
orientation controlled nanosheet/pNIPAm composite gel.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
78
OL 4-6
Strong and tough hydrogels with highly ordered and controllable
microstructure
Xiao Liu, Jian Hu*
(State Key Laboratory for Strength and Vibration of Mechanical Structures, School of Aerospace
Engineering, Xi’an Jiaotong University, Xi’an 710049, China.)
*E-mail: [email protected]
Hydrogels are similar to biological tissues owing to their specific soft and wet
properties, which are regarded as promising alternatives for artificial tissues. However,
conventional hydrogels are isotropic and lack the ordered internal microstructures,
which are far from the true structural and mechanical features of load-bearing soft
tissues such as muscle and cartilage. Herein, on the basis of mask photolithography
and double-network enhancement principle, we design a new type of soft-hard hybrid
hydrogel composites with well-ordered and controllable microstructure, where the
hard and soft phase are fabricated under the unmasked and masked region,
respectively. All of the obtained hydrogels with different patterns exhibit high tensile
strength, large stretchability, and high toughness. Especially, the striped hydrogels
exhibit remarkable anisotropic mechanical characteristic, as well as higher toughness
than both the hard and soft constituents. We further study the fracture process of the
striped hydrogels under uniaxial tensile by combining macroscopic mechanical test
with microscopic internal observation. A coupled stress-strain curve resulted from the
hard and soft phase is observed, and the decoupling process gives a clear physical
picture of the fracture and deformation of the hard and soft phase. This work provides
a new strategy to prepare strong and tough hydrogels with highly ordered and
controllable microstructure, which will make hydrogel materials better realize the
mechanical performance and functions of natural soft tissues.
Keywords: Hydrogels, Microstructure, Toughness, Fracture process, Double-network
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
79
OL 5-1
Structural constructions and multi-functions of biodegradable
polyurethanes
Feng Luo§§§§§§§
, Hong Tan
(College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials
Engineering, Sichuan University, Chengdu 610065, China)
*E-mail: [email protected]
In this report, we will introduce a series of biomedical polyurethanes (PU) with
various biological functions including antibacteria & antifouling, controlled
biodegradation, shape-memory, and so on, by elaborated multiblock design [1-4]. We
will try to uncover the coordinated relations between the multiblock construction of
PUs and the realization of biological functions.
Our findings indicate that the combination of antibacterial upper-layer and
antifouling sub-layer endow these surfaces strong, long-lasting antifouling and
contact-active antibacterial properties, with a more than 99.99% killing efficiency
against both gram-positive and gram-negative bacteria attached to them (Fig.1). Also,
a new Fmoc-diphenylalanine (Fmoc-FF) based peptide extender (PPE) is synthesized
for preparing a series of waterborne polyurethanes (WPUs) to construct a hydrophilic
surface and a hydrophobic subsurface (Fig.2). Such an architecture endows WPU
films with simultaneous biocompatibility, antifouling ability, and water resistance
under wet conditions.
Keywords: biodegradable polyurethanes, structural constructions, multi-functions
References:
This research was supported by the National Natural Science Foundation of China (Grant No.
51673126, 51873117, 51573114, 51425305).
Fig.1. The schematic of antibacterial and
antifouling gemini quaternary ammonium
salt WPU films.
Fig.2. hydrophilic surface and hydrophobic
subsurface constructed from waterborne
polyurethanes containing self-assembling
peptide extender.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
80
1. Zhang F, Luo F *, Tan H * et.al., J. Mater. Chem. B, 2018,6, 4326.
2. Wang R, Luo F *, wang y* et.al., Macromolecular Bioscience, 2018,18(6),1800054.
3. Liu W, Luo F *, Tan H * et.al.,Macromolecular Rapid Communications,2017,38,1700450.
4. He W, Li J *, Tan H*, et.al., Scientific Reports, 2016, 6, 32140.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
81
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Inducing Molecular Isomerization Assisted by Water
Dongsheng Wang*, Haiquan Zhao, Lei Zhao, Yonghao Zheng
(School of Optoelectronic Science and Engineering, University of Electronic Science and
Technology of China, No. 4, Section 2, North Jianshe Road, 610054, Chengdu, China.)
*E-mail: [email protected]
Donor-acceptor Stenhouse adducts (DASAs) are novel photoresponsive
molecules which were firstly synthesized in 2014 [1]. However, light is not the only
stimulus that can induce linear-to-cyclic isomerization of DASAs. In the present
research, the water-induced linear-to-cyclic isomerization of DASAs was
demonstrated and understood by density functional theory (DFT) calculations
(Scheme 1a). More importantly, the linear-to-cyclic isomerization is reversible under
heating. DASAs were applied in color switching under water vapor and heating
control (Scheme 1b). Stable cyclic DASAs coordinated with H2O molecules (cyclic
DASAs·xH2O) were isolated for the first time, which are useful for preparing
invisible inks for hand-writing and printing (Scheme 1c).
Scheme 1. Schematic illustration of light- and water-induced isomerization of DASAs
(a) and the related applications in color-switched inks (b) and invisible inks (c).
Keywords: DASAs, water-induced isomerization, DFT, invisible inks
References:
[1] Helmy, S.; Oh, S.; Leibfarth, F. A.; Hawker, C. J.; Read de Alaniz, J. J. Org.
Chem. 2014, 79, 11316-11329.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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OL 5-3
Rational design of UCST polymers as functional materials guided by
a thermodynamic map
Chuanzhuang Zhao1, 2*, Louis Dolmans,2 Luqin Hua,1 X. X. Zhu2
(1 Faculty of Material Science and Chemical Engineering, Ningbo University, Ningbo, Zhejiang
315211, China. 2 Department of Chemistry, Universite de Montréal, C.P. 6128, Succursale
Centre-ville, Montreal, QC H3C 3J7, Canada;)
*E-mail: [email protected]
The rational design of polymers with tunable thermo-responsiveness is of both
theoretical and practical importance. In contrast to polymers with lower critical
solution temperature (LCST), polymers with upper critical solution temperature
(UCST) in aqueous milieu are relatively rare. We have proposed a thermodynamic
map to guide the rational design of such polymers.[1] The map is based on the
enthalpic and entropic contributions (ΔHm and ΔSm) to the free energy change of
mixing (ΔGm). The map is divided into four regions: soluble, insoluble, upper critical
solution temperature (UCST), and lower critical solution temperature (LCST), with
two lines representing the freezing and boiling point of water as two boundaries for
the UCST and LCST areas. The UCST or LCST of a polymer can be predicated as the
slope of the straight line that passing through the original point and the location of the
polymer on the map. With the help of such a map, we attempt to illustrate how the
UCST and LCST are affected by the interactions in polymer aqueous solutions, such
as hydrophobic interaction, hydrogen bonding and ionic interaction, so that the
thermo-responsive properties of a polymer can be predicted before synthesis. We
would also present our new designs of UCST polymers with multiple responsiveness
and UCST self-actuating hydrogels, which provides paradigms for the rational design
of UCST polymers as novel functional materials.
Keywords: thermo-responsive, UCST, hydrogen bond, hydrogel, actuator
References:
[1] Zhao C.,* Ma Z., Zhu X. X.,* Prog. Polym. Sci., 2019, 90, 269–291.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
83
OL 5-4
Biocompatible photoluminescent silk fibers with stability and
durability
Yuan He1, Li Mei Zhang1, Yong Mei Chen1,2********
(1State Key Laboratory for Strength and Vibration of Mechanical Structures, International
Center for Applied Mechanics, School of Aerospace Engineering, Xi’an Jiaotong University, Xi’an
710049, China. 2Key Laboratory of Leather Cleaner Production, China National Light Industry,
National Demonstration Center for Experimental Light Chemistry Engineering Education,
College of Bioresources Chemical and Materials Engineering, Shaanxi University of Science &
Technology, Xian 710021, China;)
*E-mail: [email protected]
Exploring photoluminescent silk fibers, possessing biocompatibility as well as
stable and durable fluorescent properties, is a requirement for the development of
novel photoluminescent biomaterials. Herein, we fabricate photoluminescent silk
fibers, TPCA@SF, via modifying an organic fluorescent molecule
(5-oxo-3,5-dihydro-2H-thiazolo [3,2-a] pyridine-7-carboxylic acid, TPCA) onto silk
fibers, along with using quaternary ammonium salt didodecyldimethylammonium
bromide (DDAB) as color fixing agent. The hydrogen bonds and electrostatic
association among silk fibers, TPCA and DDAB ensure the stable modification. The
facile and green fabrication process is achieved in water under mild conditions
without using any toxic substances. The TPCA@SF manifests the combining features
of high quantum yield, fluorescence water-fastness, anti-photobleaching, good
mechanical property and biocompatibility. The strategy holds great potential for
exploring various biocompatible photoluminescent substances with stability and
durability.
Keywords: Silk fibers, Photoluminescence, Wash-durability, Anti-photobleaching,
Biocompatibility
References:
[1]. Shi, L.; Yang, J. H.; Zeng, H. B.; Chen, Y. M*.; Yang, S. C.; Wu, C.; Zeng, H.;
Yoshihito, O.; Zhang, Q., Nanoscale. 2016, 8, 14374-14378
This research was supported by the National Natural Science Foundation of China (Grant No.
11674263).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
84
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From Shear-thickening Gel to Multifunctional Anti-impact Body
Armor
SHOU-HU XUAN
CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department
of Modern Mechanics, University of Science and Technology of China (USTC),
Hefei, Anhui, 230027, China
Email: [email protected] Tel: +86-551-63601702
Keywords: Shear thickening gel, Body armor, Multifunctional, Impact
The shear-thickening gel (STG) is a typical visco-elastic material whose mechanical
properties are critically enhanced under applying the external forces. It behaves like a
soft plasticine in nature state but becomes very hard when suffering an external
impact. During the transition, the impact energy is absorbed to against the
deformation, thus the STG exhibits good impact protection performance. Recently,
the development of novel anti-impact body armor against the war and sports harmer
has attracted increasing needs. Considering the high flexibility, easy sealing and
rate-sensitivity characteristics, the ST materials have wide potential applications in
energy adsorption and body protection.
In this talk, a series of multifunctional anti-impact body armors based on the STG
are designed and there mechanical properties are intensively investigated. Unpon
introducing the magnetic particles, the anti-impact performance of the final materials
is controllable. Interestingly, the conductive STG exhibits an in situ sensitivity to the
external impact while it adsorbs the energy simulteneously. The
magnetic-electric-mechanic coupling mechanism is discussed and the
structure-dependent mechanical behaivor is studied. Moreover, due to the typical
shear thickening effect, the STG is favorable to improve the impact protecting
performance of Kevlar fabric. The combining of Kevlar fabrics with STG can not
only become a comfortable light material but also provide reliable protective and
energy dissipation performance as a personal body armor.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
85
s
Fig 1. The high-speed photographs of the deformation and destruction of the samples
in the ballistic impact process.
REFERENCES
1 Wang, S., Gong, L.P., Shang, Z.J., Ding, L., Yin, G.S., Jiang, W.Q., Gong, X.L.,
Xuan, S.H., Novel safeguarding tactile e-skins for monitoring human motion
based on SST/PDMS-AgNW-PET hybrid structures, Advanced Functional
Materials, 28, 1707538, 2018.
2 He, Q.Y., Cao, S.S., Wang, Y.P., Xuan, S.H., Wang, P.F., Gong, X.L., Impact
resistance of shear thickening fluid/Kevlar composite treated with
shear-stiffening gel, Composites Part A: Applied Science and Manufacturing,
106, 82-90, 2018.
3 Xu, C.H., Wang, Y., Wu, J., Song, S.C., Cao, S.S., Xuan, S.H., Jiang, W.Q.,
Gong, X.L., Anti-impact response of Kevlar sandwich structure with silly
putty core, Composites Science and Technology, 153, 168-177, 2017.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
86
OL 5-6
A self-healing hydrogel with pressure sensitive photoluminescence for
remote force measurement and healing assessment
Weijun Li1, Qingwen Guan1, Ming Li1, Xiaojie Zhang1, Zhenhai Xia2, Quan
Xu1††††††††
(1State Key Laboratory of Heavy Oil Processing, China University of Petroleum-Beijing, 102249,
China; 2Department of Materials Science and Engineering and Department of Chemistry,
University of North Texas, Denton, Texas 76203, United States.)
*E-mail: [email protected]
Light-guiding materials capable of total internal reflection, remote mechanical
force sensing and self-healing are appealing in emerging fields including robotics and
optical force measuring instruments. However, achieving all these features in a single
material remains challenging at present. Herein, we have fabricated a
fluorescence-responsive self-healing hydrogel with a triple network structure, which
exhibits a 100% recovery in tensile strength after healing in air for 30 s and a 90%
recovery in tensile strength after healing in water for 60 s. Furthermore, this material
can resist a rotation of 1800° without breaking at the healed site. As the fluorescence
excitation intensity of the hydrogel shows a good correspondence with the forces
exerted on the hydrogel, the forces and the self-healing efficiency could be
determined by measuring the intensity of the excitation peak. The stress states of the
hydrogel in different liquids could be remotely monitored, eliminating the effect
surface contacts. With these sensing and self-healing abilities all in one, the
self-healing luminescent materials could be applied for tissue engineering,
photo-responsive biosensors, flexible light guiding devices, structural health
monitoring, etc.
Keywords: Self-healing; Hydrogel; Fluorescence-responsive; Optical force
measurement; Remote healing assessment
References:
[1]. Li M.; Li WJ.; Cai W.; Wang ZH.; Zhang XJ.; Street J.; Ong W-J.; Xia ZH, Xu
Q.* Mater. Horiz. 2019, 6, 703.
This research was supported by the National Natural Science Foundation of China (Grant No.
51875577).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
87
OL 5-7
Controlled Phase Transitions of Dipeptide-based Gels
Jinbo Fei‡‡‡‡‡‡‡‡
, Junbai Li
(Beijing National Laboratory for Molecular Sciences (BNLMS), CAS Key Lab of Colloid,
Interface and Chemical Thermodynamics, Institute of Chemistry, Chinese Academy of Sciences,
Beijing 100190, China.)
*E-mail: [email protected]
Tunable phase transitions of peptide-based supramolecular assemblies have found
wide applications. Different from traditional heat or solvent modulation, with the
cryogenic treatment at -196 oC, we observed phase transition from self-assembled
diphenylalanine organogel to hexagonal crystal. [1] The internal rearrangement of the
assembled molecules forms a crystal structure with chirality. Further, we explored
non-covalent introduction of a photoswitchable moiety to achieve reversible light
modulation of the dipeptide assembly. [2]Accompanying the isothermal recycled
gel-sol transition in a spatially controlled manner, well-defined renewable patterns
were fabricated. Also, we developed Schiff base covalent assembly to construct
dipeptide–protein hydrogels under mild condition. [3] Such assembled hydrogels are
sensitive to pH variation and simultaneously the proteins can be released without
changing the native secondary structures from the gels.
Keywords: Gel, Peptide, Molecular assembly, Phase transition
References:
[1] Liu XC#; Fei JB#; Wang AH; Cui W; Zhu PL; Li JB*, Angew. Chem. Int. Ed.
2017, 56, 2660.
[2] Li XB#; Fei JB#; Xu YQ; Li DX; Yuan TT; Li GL; Wang CL; Li JB*, Angew.
Chem. Int. Ed., 2018, 57, 1903.
[3] Yuan TT#; Fei JB#; Xu YQ; Yang XK; Li JB*, Macromol. Rapid Commun. 2017,
38, 1700408.
This research was supported by the National Natural Science Foundation of China (Grant No.
21573248 and 21872150), the Youth Innovation Promotion Association of CAS (Grant No.
2016032).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
88
OL 5-8
Histidine-based Supramolecular π-gel: Dynamic Self-assembly and
Controlled Switching of Circularly Polarized Luminescence
Guanghui Ouyang*, Dian Niu, Minghua Liu*
CAS Key Laboratory of Colloid, Interface and Thermodynamics, Institute of Chemistry,
Chinese Academy of Sciences, Beijing, 100190, China
*E-mail: [email protected]
The switching of chirality and different self-assembly pathway are widely observed
in nature[1]. Inspired by the fascinating natural phenomena, the exploration of
dynamic supramolecular systems featuring chirality switching, in particularly
inversion, from enantiomeric pure gelators has attracted great attentions recently.
However, among the reported examples, the helicity and ground-state chirality
switching are the main focuses. As for circularly polarized luminescence (CPL)[2],
which reflects the excited state chirality, although the reversible switching between
emission and quenching state are discussed, the inversion and switching of CPL has
been rarely studied. Here, by designing a pyrene-conjugated histidine gelator, we
realized the inversion and switching of supramolecular chirality as well as CPL
through the cooperation of coordination and π-stacking interaction. This work not
only contributes to understand the chirality switching phenomena observed in
complicated natural systems, but also may shed light on developing smart chiroptical
materials based on π-gel systems[3].
Keywords: Supramolecular gel, Circularly polarized luminescence, Chirality
switching, Non-covalent interactions, Dynamic assembly.
References:
[1]. Liu M. H.*; Zhang L.; Wang T., Chem. Rev. 2015, 115, 7304.
[2]. Ji L.; Sang Y.; Ouyang G.*; Yang D.; Duan P; Jiang Y.; Liu M. H.*, Angew.
Chem. Int. Ed. 2019, 58, 844.
[3]. Niu D.; Jiang Y.; Ji L.; Ouyang G.*; Liu M. H.*, Angew. Chem. Int. Ed. 2019, 58,
5946.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
89
OL 5-9
Biomimetic anisotropic hydrogel actuators
Jia Wei Zhang§§§§§§§§
, Chun Xin Ma, Xiao Xia Le, Li Wang, Tao Chen
(Division of Polymer and Composite Materials, Ningbo Institute of Material Technology and
Engineering, Chinese Academy of Science, Ningbo 315201, China)
*E-mail: [email protected]
Polymeric hydrogel actuators refer to intelligent stimuli-responsive hydrogels
that could reversibly deform upon the trigger of various external stimuli. They have
thus aroused tremendous attention and shown promising applications in many fields
including soft robots, biomimetic actuators, and so on. Inspired by the living
organisms, we have prepared a series of hydrogel actuators with anisotropic structures.
Through UV-reduction and locally polymerization, RGO-PNIPAM-PMAA hydrogel
actuator that can provide remote-controllable light-driven and thermo-, pH-, and ionic
strength-triggered multi-responsive 3D complex deformations have been achieved.
Inspired by the water self-circulation mechanism that contributes to the motion of
Mimosa leaves, we have constructed a bilayer hydrogel actuator with a UCST layer
and a LCST layer, which not only functions in water, but also in liquid paraffin and in
open-air. By combining a thermo-responsive actuating layer with a pH responsive
color-changing layer via macroscopic supramolecular assembly, a novel bilayer
hydrogel actuator with on–off switchable fluorescent color-changing function
behaviors have been developed. In addition, hydrogel actuators with integrated shape
memory function have been fabricated. Our strategy may provide new insights in the
design and fabrication of biomimetic intelligent systems.
Keywords: Hydrogel actuator, Anisotropic, Color-changing, Shape memory
References:
[1] Le XX., Zhang JW*., Chen T et al, Adv. Sci. 2019, 6, 1801584.
[2] Ma CX., Zhang JW*., Chen T et al, Adv. Funct. Mater. 2018, 28, 1704568.
[3] Zheng J., Zhang JW*., Chen T et al, J. Mater. Chem. C 2018, 6, 1320.
[4] Wang L., Zhang JW*., Chen T et al, Chem. Commun. 2018, 54, 1229.
[5] Ma CX., Zhang JW*., Chen T et al, Adv. Funct. Mater. 2016, 26, 8670.
This research was supported by the National Natural Science Foundation of China (Grant No.
51873223).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
90
OL 5-10
Bioinspired Soft Sensing and Actuating Materials
Xuemin Du*********
Shenzhen Institutes of Advanced Technology (SIAT),
Chinese Academy of Sciences (CAS), Shenzhen, PR China
*E-mail: [email protected]
Bioinspired materials are originated from the inspiration of nature, such as
chameleon and Venus flytraps. Due to their intriguing properties, these materials have
been wisely explored in various research fields like sensors, actuators, robotics, etc.
Here, we would like to present our recent progress on chameleon-inspired structural
color materials firstly, including bio-inspired fabrications and sensing applications.
Then, the Venus flytraps-like actuators, which can change their shapes accordingly
after triggered with specific solvent, near-infrared light and temperature, are
followingly introduced. Based on the rapid progress in this field, we believe
bioinspired smart materials will find great potential applications in wearable and
implantable devices.
Keywords: Bioinspired materials, Structural color, Shape morphing, Sensors,
Actuators
References:
[1]. Du X.*; Cui H.; Zhao Q.; Wang J.; Chen H.; Wang Y., Research, 2019, DOI:
10.1155/2019/6398296
[2]. Zhao Q.; Wang J.; Cui H.; Chen H.; Wang Y.; Du X.*, Adv. Funct. Mater. 2018,
1801027
[3]. Zhang L.*; Naumov P.; Du X.*; Hu Z.; Wang J., Adv. Mater. 2017, 29, 1702231
[4]. Wang J.; Zhao Q.; Cui H.; Wang Y.; Chen H.; Du X.*, J. Mater. Chem. A 2018,
6, 24748
[5]. Du X. *; Cui H.; Sun B.; Wang J.; Zhao Q.; Xia K.; Wu T. *; Humayun M. S.,
Adv. Mater. Technol. 2017, 2, 1700120
This research was supported by the National Key R&D Program of China (2017YFA0701303).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
91
OL 5-11
Hydrophobic Hydrogels with Fruit-like Structure and Functions
Hui Guo1,2, Tasuku Nakajima1,2,3, Dominique Hourdet2,4, Alba Marcellan2,4, Costantino
Creton2,4, Wei Hong2,5, Takayuki Kurokawa1,2, Jian Ping Gong1,2,3*
(1Laboratory of Soft & Wet Matter, Faculty of Advanced Life Science, Hokkaido University,
N21W11, Kita-ku, Sapporo, Hokkaido, 001-0021, Japan
2Global Station for Soft Matter, Global Institution for Collaborative Research and Education
(GI-CoRE), Hokkaido University, N21W11, Kita-ku, Sapporo, Hokkaido, 001-0021, Japan
3Institute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University,
N21W10, Kita-ku, Sapporo, Hokkaido, 001-0021, Japan
4Laboratoire Sciences et Ingénierie de la Matière Molle, ESPCI Paris, PSL University, Sorbonne
Université, CNRS, F-75005 Paris, France
5Department of mechanics and aerospace engineering, Southern University of Science and
Technology, Shenzhen, Guangdong 518055, P.R. China)
E-mail: [email protected]
Normally, a polymer network swells in a good solvent to form a gel but the gel
shrinks in a poor solvent. Here, for the first time, we report an abnormal phenomenon:
some hydrophobic gels significantly swell in water, reaching water content as high as
99.6 wt% at most. Such abnormal swelling behaviors in the non-solvent water are
observed universally for various hydrophobic organo-gels containing omniphilic organic
solvents that have a higher affinity to water than to the hydrophobic polymers. The
formation of semi-permeable skin layer due to the rapid phase separation, and the
asymmetric diffusion of water molecules into the gel driven by the high osmotic pressure
of the organic solvent-water mixing, are found to be the reasons for such abnormal
swelling. As a result, the hydrophobic hydrogels have a fruit-like structure, consisting of
hydrophobic skin and water-trapped micro-pores, to display various unique properties,
such as significantly enhanced strength, surface hydrophobicity, anti-drying, despite their
extremely high water-content. Furthermore, the hydrophobic hydrogels exhibit selective
water absorption from concentrated saline solutions and rapid water release at a small
pressure as like to squeeze juices from fruits. These novel functions of hydrophobic
hydrogels will find promising applications, for example, as materials that can
automatically take the fresh water from seawater.
Keywords: Hydrophobic hydrogel, Phase separation, Semi-permeable skin, Asymmetric
diffusion, Seawater desalination
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
92
P 1-1
Investigation of photo-crosslinkable injectable poly(vinyl alcohol)
hydrogel for cartilage repair
Yachao Li, Liusheng Zha†††††††††
(State Key Laboratory for Modification of Chemical Fibers and Polymer Materials & College of
Materials Science and Engineering, Donghua University, Shanghai, 201620, China.)
*E-mail: [email protected]
Compared to traditional bulky hydrogel, injectable hydrogel is more suitable for
the application in cartilage repair due to the fact that it can be easily placed in
complex cartilage defect site (e.g., knee joint) and subsequently in situ form a
hydrogel of the exactly required shape, which benefits the adhesion of the artificial
cartilage to surrounding tissue because of their intimate contact and the mechanical
interlocking resultant from surface microroughness. The common injectable
hydrogels based on weak interactions, such as hydrogen bond and hydrophobic
interaction, have the disadvantage of weak mechanical strength, especially
compressive strength, which makes it difficult for them to meet the requirement of
cartilage repair. In this work, the poly(vinyl alcohol) (PVA) modified by glycidyl
methacrylate (GMA) was used to prepare a photo-crosslinked injectable hydrogel for
cartilage repair. The effect of the alcoholysis degree of PVA, the grafting percentage
of GMA, the used amount of photoinitiator, UV light intensity or its irradiation time
on compressive strength of the photo-crosslinked PVA hydrogel was investigated.
Finally, based on optimization of these conditions, the photo-crosslinked PVA
hydrogel of compressive strength of 1.27 MPa was obtained, which is superior to the
human cartilage (0.5 MPa).
Keywords: Injectable hydrogel, Photo-crosslinkable, Compressive strength
References:
[1]. Sivashanmugam A.; Arun Kumar R.; Vishnu Priya M.; Nair Shantikumar V.;
Jayakumar R* , European Polymer Journal, 2015, 72,543
[2]. Liu M.; Zeng X.; Ma C.; Yi H.; Ali Z.; Mou XB.; Li S.; Deng Y*.; He NY*,
Bone Research, 2017, 5,75
This research was supported by the National Natural Science Foundation of China (Grant No.
51373030).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
93
P 1-2
A highly stretchable conductive polymer hydrogel by freeze-thaw-
shrink treatment for flexible electrodes
Lizhang Chen, Xiao Li*, Jinhui Xiao, Weiying Zhang, Xiaoguang Ying, Jianying
Huang
(Fujian Key Laboratory of Advanced Manufacturing Technology of Special Chemicals, College of
Chemical Engineering, Fuzhou University, Quanzhou 362100, China.)
*E-mail: [email protected]
Conductive polymer hydrogels combine the advantages of both conductive
macromolecules and hydrogels and play an important role in flexible electronic devices.
However, the mechanical properties and electrochemical properties often cannot meet
the requirements at the same time, which greatly limits their application. With the high
absorbent polymer hydrogel as the substrate, we developed a conductive hydrogel
composed of polyaniline and poly(acrylamide-co-sodium acrylate) by simple
freeze-thaw-shrink treatment. The conductive hydrogel exhibits a high elongation at
break of 1245% and a large area specific capacitance of 849 mF/cm2. This study
provides a new idea for the design of conductive polymer hydrogels, making it possible
to further apply conductive polymer hydrogels in flexible electronic devices.
Keywords: Conductive polymer hydrogel, Polyaniline, Freeze-thaw-shrink treatment,
Flexibility
References:
[1] Y. Huang, H.F. Li, Z.F. Wang, M.S. Zhu, Z.X. Pei, Q. Xue, Y. Huang, C.Y. Zhi,
Nanostructured Polypyrrole as a flexible electrode material of supercapacitor, Nano
Energy, 22 (2016) 422-438.
[2] W. Zeng, L. Shu, Q. Li, S. Chen, F. Wang, X.M. Tao, Fiber-Based Wearable
Electronics: A Review of Materials, Fabrication, Devices, and Applications, Adv.
Mater., 26 (2014) 5310-5336.
* This research was supported by the Special Support Program for High-level Talents of Fujian
Province and the Natural Science Foundation of Fujian Province, China (Grant No. 2019J01652).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
94
P 1-3
Peptide nanofiber hydrogels to vascularization in skin regeneration
Bin Chu1,2‡‡‡‡‡‡‡‡‡, Jin Mei He1, Chang Sheng Chen1,Mei Tu2
(1Key Laboratory of Biomedical Materials and Implant Devices, Research Institute of Tsinghua
University in Shenzhen, Shenzhen 518057, China; 2 Department of Biomedical Engineering, Jinan
University, Guangzhou 510632, China)
*E-mail: [email protected]
Capillary network plays a vital role for regenerative medicine applications,
including treatment of ischemic tissue disorders and engineering tissues that are > 200
μm thick. In this study, we designed peptide-based self-assembling nanofiber
hydrogels containing angiogenic peptide segment (Ten-2) that specifically address
this challenge. Our peptides have an innate tendency to self-assemble into nanofibers,
forming biomimetic hydrogel scaffolds which are non-immunogenic and
non-cytotoxic. The hydrogels were conducive to adhesion and proliferation of Human
fibroblasts (L929) and Human umbilical vein endothelial cells (HUVEC). Meanwhile,
they could promote the formation of HUVEC tube, denoting a promising comfortable
environment for pro-angiogenic, and in vivo studies demonstrated that the hydrogels
showed no excessive inflammatory reaction. Moreover, new blood vessels were
observed under anadesma in mouse subcutaneous implantation test, and full-thickness
skin defect repair showed the hydrogels had increased skin repair speed and provided
a suitable wound repair environment for revascularization and tissue regeneration. In
short, this work presented a angiogenic peptide based self-assembling hydrogel
scaffold with steerable injectable properties and excellent biocompatibility,
pioneering the promising applications in skin regeneration.
Keywords: peptide, self-assemble, nanofibres, hydrogel, skin regeneration
References:
[1]. Song, H.-H. G.; Rumma, R. T.; Ozaki, C. K.; Edelman, E. R.; Chen, C. S., Cell
stem cell. 2018, 22, 340-354.
[2]. Rouwkema, J.; Rivron, N. C.; van Blitterswijk, C. A., Trends in biotechnology.
2008, 26, 434-441.
[3]. Griffith, L. G.; Naughton, G., Science, 2002, 295, 1009-1014.
This research was supported by the National Natural Science Foundation of China (Grant
No.51403116) and the Natural Science Foundation of Guangdong Province (2015A030313698).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
95
P 1-4
Anti-freezing ZwitterionicPoly(ionic liquid) hydrogel-based
multimodal artificial skin
Ziyang Liua,†,Yue Wangb,†,Yongyuan Rena,Ying Yangc,Wei Chenc,*,Feng Yan a,*
aDepartment of Polymer Science and Engineering, College of Chemistry, Chemical
Engineering and Materials Science, Soochow University, Suzhou 215123, China; bDepartment of Electrical and Computer Engineering, University of Illinois at
Urbana-Champaign, Urbana, Illinois 61801, USA; cResearch Centerfor Smart Wearable Technology, Institute of Textiles and Clothing, The Hong
Kong Polytechnic University, Hong Kong 999077, P. R. China.
*E-mail: [email protected]
Ionotronic devices, capable of transmitting electrical signals over long distance,
are of great significance in soft robots, wearable devices and artificial sensors.
However, profound challenges remain in the adaptability of ionotronic devices to
varied environmental conditions, such as low temperature. Herein, an anti-freezing
zwitterionic poly(ionic liquid) hydrogel (PIL gel) was designed and synthesized for
the application of a multimodal artificial skin. Thezwitterionic PIL gel exhibited
super-stretchability at -20 ℃ (~900 %), self-healing ability and high conductivity
even under a low temperature (-30℃). Based on our zwitterionic PIL hydrogel, three
modes in one device, including capacitive, resistive and triboelectric sensing modes,
can be easily switched according to different ranges of pressure, strain, and
temperature. This work not only presents a novel structure for tough hydrogel below
water freezing temperature but also provided a simple design and fabrication of a
multimodal sensor, which may suggest a new approach for developing smart devices
with multifunctionality to adopt varied environmental parameters.
Keywords:poly(ionic liquid); ionic skin; multimodal sensor; anti-freezing hydrogel
References:
[1].Ziyang Liua,†,Yue Wangb,†,Yongyuan Rena,Ying Yangc,Wei Chenc,*,Feng Yan
a,*in preparation.
This work was supported by the National Nature ScienceFoundation for Distinguished Young
Scholars (21425417),the National Natural Science Foundation of China (21835005, U1862109),
and by the Priority AcademicProgram Development of Jiangsu Higher EducationInstitutions.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
96
P 1-5
Synthesis and properties of a Tough and multifunctional hydrogel
based on grape seed polymer
Chun Hui Luo1§§§§§§§§§, Ning wei1
(1College of Chemistry and Chemical Engineering, North Minzu University, Yinchuan, Ningxia
750021, China.)
*Email: [email protected]
The development of hydrogel with superior mechanical properties and
multi-functionalities has attracted enormous scientific interests. Herein, a tough and
multifunctional hydrogel, comprised of grape seed polymer and hydrophobically
associated polyacrylamide (GSP-HPAM) double network, is fabricated by simply
mixing and in-situ polymerization. The GSP-HPAM DN hydrogel exhibit improved
mechanical properties, i.e., the tensile strength, strain and compression stress of
GSP/HPAM DN hydrogel are 0.7 MPa, 3000% and 28.3 MPa, respectively, which are
5-, 2.5- and 3-fold higher than that of pure HPAM hydrogel. Besides, the GSP-HPAM
DN hydrogels are free-shapeable, crack-resistant, notch-insensitive and self-healable,
which might arise from the combination of hydrophobic interaction of HPAM and
ionic bond between GSP and calcium ions. Due to the introduction of GSP, the DN
hydrogel also exhibits pH-sensitivity, radical scavenging ability, UV-blocking
property and electrical conductivity. These GSP-based DN hydrogels might expand
the application areas of hydrogels into controlled drug release and artificial skin.
Keywords: Grape seed polymer, pH-sensitivity, Radical scavenging ability,
UV-blocking property, Electrical conductivity
References:
[1]. Taylor, D. L.; In Het Panhuis, Advanced Materials. 2016, 28 (41), 9060-9093.
[2]. Keplinger, C.; Sun, J. Y.; Foo, C. C.; Rothemund, P.; Whitesides, G. M.; Suo, Z.,
Science 2013, 341 (6149), 984-7.
This research was supported by the National Natural Science Foundation of China (Grant No.
21464001).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
97
P 1-6
Physically cross-Linked hydrogel with toughness, high stretchability,
biocompatibility, conductivity, and self-healability
Wenjing Ma 1, Guodong Fu1*
(1 School of Chemistry and Chemical Engineering, Southeast University, Jiangning District,
Nanjing, Jiangsu Province, 211189, China.)
*E-mail: [email protected]
Hydrogels are a class of chemically and/or physically cross-linked networks of
hydrophilic polymer chains. The special porous three-dimensional network structure
has enabled them to be widely applied in tissue engineering, waste treatment, and
electronic devices etc. However, conventional chemically cross-linked hydrogels are
often relatively weak and/or brittle, which limits hydrogels from wider applications.1
A novel physically cross-linked Xanthan gum (XG)/ Montmorillonite (MMT)/ poly
(acrylamide-co-acrylonitrile) Poly (AAm-co-AN) hydrogel is synthesized for
addressing the above drawbacks. The hydrogel could effectively dissipate energy and
obtain excellent fatigue-resistance and self-healing abilities. We expect that this
strategy can provide a new perspective for fabricating a unique multi-cross-linked
hydrogel with adjustable mechanical strength, as well as recovery, self-heal,
conductive, and fatigue-resistance properties, which would further widen the
application of hydrogel in modern high-tech fields.
Keywords: Hydrogel, Self-healing, Toughness, Stretchability, Biocompatibility
References:
1. K. Haraguchi and T. Takehisa, Advanced materials, 2002, 14, 1120-1124.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
98
P 1-7
Reverse Photochromic hydrogel with self-healing property for
potential rewritable display application
Mengmeng Kang1, Guodong Fu 1**********
(1 School of Chemistry and Chemical Engineering, Southeast University, Jiangning District,
Nanjing, Jiangsu Province, 211189, China.)
*E-mail: [email protected]
Reverse photochromic materials, which tuned by harmless visible light, could be
grant access to novel applications, such as anti-counterfeiting technologies, rewritable
displays, and optical data storage systems. Here, we developed a reverse
photochromic hydrogel based on 6-nitro-substitution spiropyran
(1-(beta-carboxyethyl)-3,3-dimethyl-6'-nitrospiro(indoline-2,2'-2H-benzopyran)) with
self-healing property, which could be colored by visible light and transform between
photochromic and fluorescence by treating with HCl and NH4OH. Here, the
self-healing hydrogel PVA-glycerol-borax was developed with abundant amount of
hydrogen bonds, dynamic B-O bonds and B-N bonds between borax and indole
nitrogen of spiropyran. Most importantly, the boron-nitrogen could enhance the
reverse photochromic phenomenon. The self-healing reverse photochromic hydrogel
has potential for using as rewritable displays with a long-span. This work provides a
method for reverse photochromic in the field of hydrogel, which will hopefully
expand applications of hydrogel in tunable rewrite displays.
Keywords: Self-healing, Reverse photochromism, Hydrogel, Rewritable display
References:
[1]Julialopez, D. Ruizmolina, J. Hernando, C.J.A.A.M. Roscini, Interfaces, 11 (2019)
11884-11892.
[2]. Shinmori, M. Takeuchi, S.J.J.o.t.C.S.P.T. Shinkai, 7 (1996) 1
This research was supported by the National Natural ScienceFoundation of China (Grant No. 326
9Z07040007D6).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
99
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CO2 sensitive self-supporting cellulose hydrogel as food spoilage
indicator
Xiao Hui Ge1, Lu Zheng1, Ren Liu1, Peng Lu1,2
(1.Institute of Light Industry and Food Engineering, Guangxi Key Laboratory of Clean Pulp and
Papermaking and Pollution Control, Guangxi University, Nanning, 530004, , China; 2.Jiangsu
Provincial Key Laboratory of Pulp and Paper Science and Technology, Nanjing Forestry
University, Nanjing, Jiangsu Province, 210037, China.)
A self-supporting cellulose hydrogel was prepared by gelation of the
TEMPO-oxidized bagasse cellulose nanofibrills (CNF) triggered by strong crosslink
between carboxylate groups on CNF and Zn2[object Object]. CNFs were fined down
to 200–500 nm after TEMPO process, with carboxylate contents 1.29 mmol/g. A
sound hydrogel was prepared at TOCNFs concentration of 3.0 wt% and zinc ions
concentration of 0.2mol/l. CO2 sensitive cellulose hydrogel indicator was prepared by
incorporating bromothymol blue and methyl red. For fresh-cut fruits, a clear color
change of cellulose hydrogel from dark green to orange yellow was observed during 7
days storage. Color changes correlated well with CO2 levels and micro-organisms
proliferation, which associated food spoilage. This bagasse derived CNFs hydrogel
can be fabricated to CO2 sensitive indicators for use in intelligent food packaging.
Keywords: Hydrogel; Cellulose Nanofibrills, CO2 sensitive, Spoilage indicators
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
100
P 1-9
Flexible semi-IPN network gel polymer electrolyte for supercapacitor
Mengxiao Wang, Chaowei Yin, Yu Chen, Ting Zhai, Yuanyuan Shi, Yueming Fan,
Gang Qin*, Jia Yang and Qiang Chen**
(School of Materials Science and Engineering, Henan Polytechnic University, Jiaozuo, 454003
China.)
*E-mail: [email protected] (G. Qin), [email protected] (Q. Chen).
Abstract: To meet the requirement of the flexible supercapacitors, the enhancement
of the mechanical properties of the gel polymer electrolyte (GPE) attracts more and
more attention. Here a novel PAM-PVP GPE has been developed with a
semi-interpenetrating (semi-IPN) structure, which results in the superior flexibility
and stretchability (elongation at break of 17.42 mm/mm), meantime, the ionic
conductivity reaches 0.138 S/cm. The PAM-PVP-H3PO4 GPE supercapacitor shows
outstanding cycle stability and can bear complex deformations including bending and
stretching. In addition, it possesses the stable electrochemical performances (65%
capacitance retention) at -20 ℃. The supercapacitor is promising for the application
in the flexible electronic devices under low temperature condition.
Keywords: Gel polymer electrolyte; Polyacrylamide; Semi-interpenetrating network;
Flexible supercapacitor; Low temperature resistance
References:
[1] Guo, X.; Bai, N.; Tian, Y.; Gai, L. J. Power Sources. 2018, 408 : 51-57.
[2] Wang, J.; Zhao, Z.; Muchakayala, R.; Song, S. J. Membr. Sci. 2018, 555:
280–289.
[3] Lv, P.; Li, Y.; Wu, Y.; Liu, G. ACS Appl. Mater. Interfaces. 2018, 10:
25384−25392.
[4] Na R,; Wang, X.; Lu, N.; Huo, G. Electrochim. Acta. 2018, 4:127.
[5] Tao, F.; Qin, L.; Wang, Z.; Pan, Q. ACS Appl. Mater. Interfaces. 2017, 9:
15541-15548.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
101
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All-in-one configured stretchable flexible supercapacitor with high
strength, excellent self-recovery and self-healing performances
Xianqiang Yu1, Xiangbin Sun1, Yu Li1, Gang Qin1, Jia Yang1††††††††††, Qiang Chen1*
(1 School of Materials Science and Engineering, Henan Polytechnic University, Jiaozuo, 454000,
China.)
*E-mail: [email protected]
The development of all-in-one configured supercapacitors with integrated high
performances (e.g. capacitance, strength, toughness, flexibility, self-recovery and
self-healing) is still a tremendous challenge. Herein, a novel, strong, tough multiple
hydrogen-bonds cross-linked polyvinyl alcohol/poly (N-hydroxyethyl acrylamide)
(PVA/PHEA) hydrogel electrolyte (HGE) were prepared. Moreover, the strong, tough,
recoverable and healable all-in-one configured PVA/PHEA/ polyaniline (PANI)
supercapacitor with the sandwich-like laminated structures was prepared by in situ
rapid polymerization of the aniline in high concentration, which can quickly deposit
to the upper and lower surfaces of the as-prepared HGE for avoiding the swelling of
the HGE. The multiple hydrogen bonds, rapid polymerization and deposition
endowed all-in-one configured PVA/PHEA/PANI supercapacitor with integrated
performances, where the PVA/PHEA/PANI film had excellent mechanical properties
(tensile strength of 1.07 MPa and tearing energy of 2492 J/m2). The all-in-one
configured supercapacitor exhibited high surface capacitance (98 mF/cm2), good
cycle stability and excellent flexibility. In addition, the supercapacitor exhibited
excellent capacitance retention during and after the deformations. In particular, it also
had high capacitance self-recovery and self-healing abilities. Thus, the current work
presents a novel and promising strategy to design the integrated high-performance
supercapacitors aiming for wearable electronics.
Keywords: Flexible supercapacitor, Multiple hydrogen bonds, High strength
References:
[1]. Hu XY.; Fan LD.; Qin G*.; Shen ZS.; Chen J.; Wang MX.; Yang J; Chen Q*, J.
Power Sources, 2019, 414, 201-209
[2]. Guo Y.; Zheng KQ; Wan PB*, Small, 2018, 14, 1704497
This research was supported by the National Natural Science Foundation of China (Grant No.
21504022).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
102
P 1-11
Complex Deformation of Bilayer Hydrogels Based on Shape Memory
Hydrogel and Elastic Hydrogel
Qilin Wang1, Qiang Chen1,‡‡‡‡‡‡‡‡‡‡
(1School of Materials Science and Engineering, Henan Polytechnic University, Jiaozuo 454003,
China.)
*E-mail: [email protected]
Shape memory hydrogels with stimulus response properties have drawn much
attention in the field of bio-actuators and soft robots [1]. Herein, we presented a bilayer
structure hydrogel based on a shape memory hydrogel (S-gel) and an elastic hydrogel
(E-gel), which could exhibit complex deformation. Owing to their self-healing
properties, the two gels could be easily and toughly adhesive together to form the
bilayer hydrogel via hydrophobic interactions as heat treatment, the adhesion energy
could be up to 2000 J/m2. Various shapes of the bilayer gel could be achieved by
stretching, heating-cooling treatment, or combination of the above mentioned
methods. The bilayer hydrogels showed fast responsive properties, which could be
used as grippers.
Keywords: Shape memory hydrogels, Bilayer Hydrogels, Complex Deformation
References:
[1]. Wei, D.; Yang, J.; Zhu, L.; Chen, F.; Tang, Z.; Qin, G.; Chen, Q., Semicrystalline
Hydrophobically Associated Hydrogels with Integrated High Performances. ACS
Applied Materials & Interfaces 2018, 10 (3), 2946-2956.
This research was supported by the National Natural Science Foundation of China (Grant No.
21504022 and U1304516).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
103
P 1-12
Hybrid Cross-linked Natural Protein Hydrogels with High Strength
Shaoping Lu1, Qiang Chen1,§§§§§§§§§§
(1School of Materials Science and Engineering, Henan Polytechnic University, Jiaozuo 454000,
China.)
*E-mail: [email protected]
Natural protein-based hydrogels possess excellent properties, however, most of
them are weak or brittle[1,2]. Herein, bovine serum albumins (BSA)-based gels with
dually cross-linked network structure (DC-BSA gels) were prepared. Compared to
BSA gels with single network structure, DC-BSA gels, consisting of covalent
dityrosine bonds and physical interactions caused by thermal denaturation, exhibited
high strength (35 MPa), fast recovery (stiffness recovery of 77% and toughness
recovery of 60% at room temperature for 3 min resting) and good fatigue resistance.
Moreover, DC-BSA gels also demonstrated excellent biocompatibility. We hope our
DC-BSA gels can be applied in the field of load-bearing soft tissues.
Keywords: Natural Protein Hydrogels, Dual Cross-linking, High Strength,
Self-Recovery, Biocompatibility
References:
[1]. Tang ZQ.; Chen Q*.; Chen F.; Zhu L.; Lu SP.; Ren BP.; Zhang YX.; Yang J.;
Zheng J* , Chem. Mater. 2019, 31,179
[2]. Chen, Q*., Zhu, L., Zhao, C., Wang, Q., & Zheng, J*. Advanced materials,
2013,25, 4171.
This research was supported by the National Natural Science Foundation of China (Grant No.
21504022 and U1304516).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
104
P 1-13
Body-Temperature Responsive Ultrafast Shape Memory Hydrogel
Based on Natural Materials
Shurui Yang, Hongfang Liao, Chao Zhang, Qiqian Hu, Tao Wang,* and Zhen
Tong***********
School of Materials Science and Engineering, South China University of Technology, Guangzhou 510640, China
E-mail: [email protected], [email protected]
Shape memory hydrogels are a unique class of soft materials that have the
capacity to response to the external stimuli. They have demonstrated promising
applications in many fields, such as soft robots, smart drivers, artificial muscles and
so on. However, there are still many challenges for the existing shape memory
hydrogels, such as facile preparation methods, the fixation rate and response rate.
In this work, we prepared a hydrogel based on natural materials through a facile
method which could fix the temporary shape and recover to original shape quickly.
First of all, the gelatin hydrogel was prepared at low temperature due to the triple
helix structure. After that, the gelatin hydrogel was soaked in tannic acid solution for
hours. Finally, the hydrogel was soaked in hot water and the hydrogel was obtained.
As shown in Figure 1, the hydrogel can be fixed temporary shape in 25 ℃ water
for 1 s after immersing in 37 ℃ for 2 s and recover to original shape in 37 ℃ water
for 1 s. It is worth noting that this is a transition between room temperature and body
temperature. What’s more, there is a 100 % fixation and recovery for the hydrogel.
Because of its facial preparation, natural materials and body-temperature
response, it provides a possibility for shape memory hydrogel to be used in the
biomedical field.
Keywords: Hydrogel, Ultrafast shape memory, Body-temperature response
This research was supported by the NSFC (51573060 and 21427805) and the Pearl River S&T
Nova Program of Guangzhou (201710010146).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
105
P 1-14
One-Step Synthesis of Healable Weak-Polyelectrolyte-Based
Hydrogels with High Mechanical Strength, Toughness, and Excellent
Self-Recovery
Xu Fang and Junqi Sun *
(State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin
University, Changchun 130012, P. R China)
*E-mail: [email protected]
Excellent self-recovery is critically important for soft materials such as hydrogels
and shape memory polymers. In this work, weak-polyelectrolyte-based hydrogels
with high mechanical strength, toughness, healability and excellent self-recovery are
fabricated by one-step polymerization of acrylic acid and poly(ethylene glycol)
methacrylate in the presence of oppositely charged branched polyethylenimine. The
synergy of electrostatic and hydrogen-bonding interactions and the in-situ formed
polyelectrolyte complex nanoparticles endow the hydrogels with a tensile strength of
~4.7 MPa, strain at break of ~1200% and toughness of ~32.6 MJ m-3. The hydrogels
can recover from a ~300% strain to their initial state within 10 min at room
temperature without any external assistance. Moreover, the hydrogels can heal from
physical cut at room temperature and exhibit a prominent shape-memory performance
with rapid shape recovery speed and high shape-fixing and shape-recovery ratios.
Keywords: Hydrogels, Mechanical properties, Shape memory, Supramolecular
chemistry
References:
[1]. Xu Fang and Junqi Sun *, ACS Macro Lett. 2019, 8, 500−505
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
106
P 1-15
Preparation and Properties of Nanocomposite Hydrogels
Cross-linked by Alumina Nanoparticles
Bo Xu†††††††††††
, Jiugang Yuan, Yuanyuan Yu, Ping Wang, Qiang Wang
Key Laboratory of Eco-Textile, Ministry of Education, College of Textile and
Clothing, Jiangnan University, Wuxi 214122, P. R. China
*E-mail: [email protected]
Hydrogels have attracted much attention in various areas due to their unique
physicochemical properties. However, the poor mechanical performance severely
limited their practical applications. It is well-known that the introduction of inorganic
nanomaterials into the polymer matrix as the cross-linking agents could significantly
enhance the toughness and strength of the resultant hydrogels [1]. Based on this
knowledge, a novel kind of nanocomposite hydrogels were prepared by in situ free
radical copolymerization of acrylic acid with other vinyl monomers such as N,
N-dimethylacrylamide (DMAA), 2-acrylamido-2-methylpropane sulfonic acid
(AMPS) and N-vinyl-2-pyrrolidone (NVP). The resultant hydrogels not only exhibit
outstanding mechanical properties, but also reveal some unique characteristics
including high transparency, swelling-resistance, self-healing and anti-fogging,
depending on their different components [2-4]. It is expected that this novel type of
hydrogel would have great promise for various applications, including soft robots,
artificial muscles, and optical devices.
Keywords: Hydrogels, High-strength, Alumina, Anti-fogging, Self-healing.
References:
[1]. Haraguchi K.; Takehisa T. Adv. Mater. 2002, 14, 1120.
[2]. Xu B.; Wang LL.; Liu YW.; Zhu HL.; Wang Q*. Matter. Lett. 2018,228, 104.
[3]. Xu B.; Liu YW.; Wang LL.; Ge XD.; Fu M.; Wang P.; Wang Q*. Polymers 2018,
10, 1025.
[4]. Xu B.; Yuan JG.; Wang P.; Wang Q*. Polymers 2018, 10, 1362.
This research was supported by the National Natural Science Foundation of Jiangsu Province
(Grant No. BK20180631).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
107
P 1-16
Tough hydrogels with strong, fast and reversible underwater
adhesion
Ping RAO1, Taolin SUN2,3, Liang Chen1, Riku Takahashi1, Daniel R. King2,3,
Takayuki KUROKAWA2,3, Jian Ping GONG2, 3*
(1Graduate School of Life Science, Hokkaido University, Sapporo 001-0021, JAPAN, 2Faculty of
Advanced Life Science, Hokkaido University, Sapporo 001-0021, JAPAN, 3Global Institution for
Collaborative Research and Education (GI-CoRE), Hokkaido University))
*E-mail: [email protected]
Hydrogels containing large amount of water are usually considered to show poor
underwater adhesion performance while it has potential application in diverse area
with wet environment including tissue engineering, bio-medical device, and even soft
robotics. Existing hydrogels showing poor underwater adhesion performance is
mainly because of limitation such as low robustness, weak interfacial bonding and
competition between adhesive interaction and interaction with water molecules. Here,
we propose a simple but effective method to design tough underwater adhesion of soft
gels. The designed hydrogels possess high robustness, strong physical interfacial
bonds, fast contact formation and reversible underwater adhesion on soft hydrogels.
The main ideas of this method are briefly described as follows. First of all, we
need tough materials to bear large deformation and high impact. Soft tough materials
are usually composed of stretchable polymer networks with sacrifice bonds. To design
reversible adhesives underwater, the sacrifice bonds should be recoverable such as
physical bonds (ionic bonds or hydrogen bonds). Second, surface channels are
introduced to prevent large drop of water from being trapped between the interfaces
resulting in reduction of real contact area. The water between the surfaces can be
drained out through these channels under normal pressure load. Third, the surface is
divided into many independent parts by the channels. The "lost" of one part will not
affect the others, to overcome all the discontinues parts, it requires frequent
re-initiation of the interface crack and the failure of the interface therefore occurs at
higher stress and more energy dissipation.
Keywords: Tough hydrogels, underwater adhesion, fast, reversible, trapped water
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
108
P 1-17
A Highly stretchable, tough and fast self-healing hydrogel based on
peptide-metal ion coordination
Ying Li1‡‡‡‡‡‡‡‡‡‡‡, Bin Xue2, Yi Cao2
(1Collaborative Innovation Center of Atmospheric Environment and Equipment Technology,
Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control, School of
Environmental Science and Engineering, Nanjing University of Information Science & Technology,
Nanjing 210044, China, 2Collaborative Innovation Center of Advanced Microstructures, National Laboratory of Solid
State Microstructure, and Department of Physics, Nanjing University, Nanjing 210093, China.)
*E-mail: [email protected]
Metal coordination bonds are widely used as the dynamic cross-linkers to
construct self-healing hydrogels. However, it remains challenging to independently
improve the toughness of metal coordinated hydrogels without affecting the
stretchability and self-healing properties, as all these features are directly correlated
with the dynamic properties of the same metal coordination bonds. In this work, using
histidine-Zn2+ binding as an example, we show that the coordination number (the
number of binding sites in each cross-linking ligand) is an important parameter for the
mechanical strength of the hydrogels. By increasing the coordination number of the
binding site, the mechanical strength of the hydrogels can be greatly improved
without sacrificing the stretchability and self-healing properties. By adjusting the
peptide and Zn2+ concentrations, the hydrogels can achieve a set of demanding
mechanical features, including the Young’s modulus of 7-123 kPa, the fracture strain
of 434-781%, the toughness of 630-1350 kJ m-3, and the self-healing time of ~1 h. We
anticipate the engineered hydrogels can find broad applications in a variety of
biomedical fields. Moreover, the concept of improving the mechanical strength of
metal coordinated hydrogels by tuning the coordination number may inspire the
design of other dynamically cross-linked hydrogels with further improved mechanical
performance.
Keywords: Gel, Self-healing, Metal chelation, Coordination number
This research was supported by the National Natural Science Foundation of China (Grant No.
21522402, 11674153, 81622033, 21774057 and 11804148).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
109
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Asymmetric interpenetrating UCST polymer network as
multiple-responsive hydrogel actuator
Luqin Hua, Manqing Xie, Chuanzhuang Zhao*
( Faculty of Material Science and Chemical Engineering, Ningbo University, Ningbo, Zhejiang
315211, China. )
*E-mail: [email protected]. c n
Thermo-responsive hydrogels have attracted tremendous interest due to their
promising applications in artificial muscles, soft robotics, and flexible electronics.
However, most of these materials are based on polymers with lower critical solution
temperature (LCST), while those from upper critical solution temperature (UCST) are
rare. Herein, we report a multiple-responsive UCST hydrogel actuator based on the
complex of poly(acrylic acid) (PAA) and poly(acryl amide) (PAm). By applying an
asymmetric photo-polymerization process, a bilayer hydrogel is obtained, including a
layer of interpenetrating network of PAA/PAm and a layer of single network of PAm.
When cooled down below the UCST, the PAA/PAm layer is dehydrated due to the
hydrogen bonding of the two polymers while the PAm layer stays in swelling state,
driving the bilayer hydrogel to curl. Active motion can be realized in both aqueous
and oily milieu, thanks to the internal water exchange between the two layers.
Moreover, the hydrogel can be actuated with the stimuli of urea, a molecule that can
disrupt the hydrogen bonding between PAA and PAm. Interestingly, the bilayer
hydrogel actuator is also sensitive to the addition of salts (Na 2 SO 4 , NaCl, NaSCN),
and the behavior follows a typical Hofmeister series, rending itself with the
application of ion-sensitive actuator. Overall, the current study reveals a novel
strategy to design thermo-responsive actuator, which is to tailor the distribution of
hydrogen bond-former inside the polymer network.
Keywords: hydrogel actuator, interpenetrating network, UCST, hydrogen bond
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
110
P 1-19
A shape memory hydrogel with editable permanent shape based on
orthogonal supramolecular interactions
Manqing Xie, Chen Wu, Chuanzhuang Zhao*
( Faculty of Material Science and Chemical Engineering, Ningbo University, Ningbo, Zhejiang
315211, China. )
*E-mail: [email protected]. cn
Shape memory hydrogels (SPHs) can maintain temporary shapes and return to
permanent shapes upon external stimuli, thus they have attracted tremendous attention
and shown promising applications in many fields. However, these SPHs cannot alter
their permanent shapes after being prepared, which restricts their reusability and their
applications. In this letter, we report the shape memory behavior of polyacrylamide
(PAAm)/alginate hydrogel cross-linked with the host-guest complex of α-cyclodextrin
and azobenzene. The hydrogel can memorize a temporary shape through coordination
with calcium ion and revert to its permanent shape in ethylenediaminetetraacetic acid
(EDTA) solution. Moreover, the permanent shape of the hydrogel, memorized by the
host-guest cross-linked PAAm network, can be erased and edited with the irradiation
of ultraviolet (UV) light, due to the photo-switchable binding strength of the
host-guest complex. Rheological study shows that the shape-erasing is conducted
through a stress relaxation process that accelerated by UV irradiation, during which
the constraints from the old permanent shape are released and the polymer network is
adapted to a new shape. In addition, the hydrogel exhibits interesting functions such
as spatial-selectivity and remote actuation, taking advantages of the unique character
of light stimuli. These novel properties of the material are attribute to the dynamic and
reversible nature of the two supramolecular interactions, host-guest interaction and
metal ion coordination, as well as their orthogonality.
Keywords: shape memory hydrogel; light-responsiveness; host-guest interaction;
metal ion coordination; viscoelasticity;
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
111
P 1-20
Color-Tunable Fluorescent Supramolecular Metallogels Constructed
by Lanthanide (Eu/Tb) Dependent Coordination Interaction
Long-Yue Yu, Xing-Dong Xu§§§§§§§§§§§
(Key Laboratory of Special Functional Aggregated Materials, Ministry of Education, National
Engineering Research Center for Colloidal Materials, Shandong University, Jinan 250100,
Shandong, China)
* E-mail: [email protected]
Supramolecular self-assembly formation of soft materials such as hydrogels have
attracted the attention of researchers across various disciplines due to the rich
potential they can provide within different fields of applications.1 New fluorochromic
soft materials that reversibly change their emission properties in response to their
environment are of interest for the development of sensors and light-emitting
materials.2 A new design of Lanthanide-containing polymer hydrogels showing
tunable fluorochromic properties and fast self-healing is reported. This study supplies
a convenient approach toward the construction of structure-tunable fluorescent
supramolecular materials with different colors.
Figure 1. Schematic representation of supramolecular structure (left) and the
emission spectra with different ratio of Eu(III) and Tb(III).
Keywords: Hydrogel, Self-assembly, Luminescent material, Coordination chemistry
References:
[1]. X.-D. Xu, X. Li, H. Chen, Q. Qu, L. Zhao, H. Ågren, Y. Zhao, Small 2015, 11,
5901.
[2]. G. Weng, S. Thanneeru, J. He, Adv. Mater. 2018, 30, 1706526.
This research was supported by the National Natural Science Foundation of China (21602124) and
the Natural Science Foundation of Shandong Province (ZR2016BQ11).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
112
P 1-21
Tough Lignin Bonded Hydrogels with Tunable Mechanical Properties
Xuelian Wang1, Xiangyu You1*, Huijie Zhang 1*, Xinping Li1
(1Department of Bioresources Chemical and Materials Engineering,
Shaanxi University of Science&Technology, Weiyang District, Xi'an, Shaanxi, 710021, China)
*E-mail: [email protected]
Hydrogels are solid jelly-like polymeric materials containing large amounts of
water due to their chemical and/or physical bonded frameworks with excellent
hydrophilic property. Hydrogels derived from lignin, an abundant highly branched
biopolymer in plants, had attracted much attention due to its naturally possessed
biocompatibility and biodegradability. However, the application of conventional
lignin hydrogels was limited by their poor mechanical properties.In this study, a series
of tough hydrogels were synthesized with the attendance of acetic acid lignins, which
basically contained hydroxyl groups, acetyl groups and C9 structure with
hydrophobicity. Based on such structural characteristics, lignin was expected to
establishstrong physical interactions, such as hydrogen bond and hydrophobic
associations, with synthetic polymer chains in strategy design. Specifically,
dimethylacrylamide (DMAAm) was first polymerized in water to form hydrogel
precursors. Subsequently, acetic acid lignin solutions were then mixed with the
resultant hydrogel precursors. The final gelation was finished through solvent
exchange process. Herein, the morphological of the hydrogel and mechanical
properties were systemically investigated. Interestingly, the tensile strength and strain
largely improved up to 2.5 MPa and 1200 %, respectively, which is 20 times higher
than those performance among conventional lignin hydrogels. In addition, the fracture
energy achieved more than 5000 J/m2 on the same scale of nature rubber.
Keywords:Lignin, Hydrogel, Physical interactions
References:
[1].Sun J Y , Zhao X , Illeperuma W R K , et al. Highly stretchable and tough
hydrogels[J]. Nature, 489(7414).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
113
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Reinforcement of gelatin hydrogel by heat-induced phase separation
Chunlin Liu1, HuijieZhang2*, XuechuanWang2*
(1School of Chemistry& Chemical Engineering, Shaanxi University of Science & Technology,
Xian 710021,2 College of Bioresources Chemical and Materials Engineering, Shaanxi University
of Science & Technology, Xian 710021, China;.)
*E-mail: [email protected]
Most protein-based hydrogels are mechanically weak. Usually, the strength of
these hydeogelsis enhanced by chemical modification or compounding with synthetic
or other natural polymers. In this work, we focus on adjusting mechanical properties
through self-aggregation of protein chains and realized highly tunable mechanical
properties of a gelatin hydrogel by simple heat-treatment.Specifically, the reported
ductile (NH4)2SO4/ gelatin hydrogel[1] was used as initial gel. By heating, the helix
junctions were destroyed and gelatin chains were supposed to aggregate and fold to
form more and denser hydrophobic aggregation due to the salt-out effect. The resulted
gel became opaque indicating phase-separation.From SAXS analysis, it was found
that upon heating the structure size increased and the aggregated part became firstly
denser than looser. Correspondingly, gel became stronger and then softer by both
increasing heating temperature and heating time. The strongest gel exhibited superior
mechanical properties of higher modulus (7.46 MPa) and fracture energy (2160 J/m2)
to thatof the initial gel (0.99MPa, 1000 J/m2), and better recovery property. The
further enhanced mechanical property would provide the gel with more potential
application in engineering area.
Keywords:Hydrogel, Gelatin, Self-aggregation,Phase separation
References:
[1].Qingyan He, Yan Huang,*Shaoyun Wang*. Adv. Funct. Mater.2018, 28, 1705069
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
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Dual physically cross-linked double network hydrogel with high
toughness and self-healing capability
Yanjie Wang, Sijun Liu************
(Advanced Rheology Institute, Department of Polymer Science and Engineering,
Shanghai Jiao Tong University, Shanghai 200240, P. R. China)
*E-mail: [email protected]
Due to the irreversible fracture of covalent bonds and cytotoxicity of chemical
cross-linking agents, traditional chemically cross-linked double network (DN)
hydrogels generally exhibit low fatigue resistance and poor biocompatibility, which
greatly limits the application of stretchable hydrogels in biological tissue engineering.
Here, based on the design of dual physical network (ionic association and
hydrophobic association), we successfully prepared the gellan gum/hydrophobically
modified polyacrylamide (GG/HPAAm) DN hydrogel with remarkable mechanical
properties: stress at break of ~800 kPa, strain at break of ~1500%, elastic modulus of
~300 kPa. Because of the reversibility of physical network fracture, the dual
physically cross-linked GG/HPAAm hydrogels exhibit excellent self-recovery at
room temperature (recovery efficiency up to 50%), and the recovery efficiency can be
further improved after the deformed and relaxed hydrogel sample underwent a cycle
of heating and cooling due to the thermoreversible gelation of GG. More importantly,
the thermoreversible gelation property also endows the self-healing capability of the
GG/HPAAm hydrogel. Therefore, this study provides a new strategy for the
preparation of biocompatible hydrogels with high mechanical properties, remarkable
recovery and self-healing capability, which expands the application of hydrogels in
the field of tissue engineering.
Keywords: Hydrogel, Dual physically cross-linked, Self-recovery, Self-healing,
Biocompatibility
References:
[1]. Chen Q.; Zhu L.; Chen H.; Yan HL.; Huang LN.; Yang J.; Zheng J*, Adv. Funct.
Mater. 2015, 25,1598-1607
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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Control of ice crystal growth and its effect on porous structure
of chitosan cryogels
Haiyan Zhang, Chunjie Liu, Liang Chen*, Bin Dai*
(Key Laboratory for Green Processing of Chemical Engineering of the Xinjiang Bingtuan,
School of Chemistry and Chemical Engineering, Shihezi University, Shihezi 832000, China)
*E-mail: [email protected] (L. Chen), [email protected] (B. Dai)
We presented an improved preparation method to generate cryogels with
controllable pore size. Itincluded 5 stages: pre-cooling, pre-crystallization, crystal
growth, freezing, and thawing (PPCFT); crystalgrowth was the key step. Chitosan (CS)
cryogels with uniform and honeycomb-like structures were preparedwith the method,
and then the properties of these cryogels were studied. The results demonstratedthat
the mean pore diameters of CS cryogels were successfully controlled in a wide range
(approximately60–240 lm, by scanning electron microscope) by simply varying the
temperature and time of crystalgrowth. The crystal growth law of this process was
described by an empirical equation based on the classicaltheory for Ostwald ripening
by Lifshitz, Slyozov, and Wagner (LSW). Furthermore, the
hydrodynamicsperformance (permeability and column efficiency) of CS cryogel
columns clearly varied with crystalgrowth conditions, while both the accessible
porosity and water absorption ratio remained at a highlevel.
Keywords:Crystal growth, Cryogels, Morphology, Pore size, Chitosan
References:
[1].Zhang HY.; Liu CJ.; Chen, L*.; Dai, B*,Controlof ice crystal growth and its effect
on porous structure ofchitosan cryogels. Chem. Eng. Sci. 2019, 201, 50.
This research was supported by the National Natural Science Foundation of China
(Grant No. 21206094).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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In-situ forming thermosensitive polyurethanes-based hydrogel
crosslinked by Diels-Alder reaction for 3D cell culture
Yan Jun Wang, Zhen Yan Bai, Zhen Li, Jie Hua Li, Feng Luo††††††††††††, Hong Tan
(State Key Laboratory of Polymer Materials Engineering, College of Polymer Science and
Engineering, Sichuan University, Chengdu 610064, China.)
*E-mail: [email protected]
Injectable hydrogels crosslinked physically have attracted much attention in
scaffolds biomedical field [1]. However, traditional hydrogels with weak strength and
uncontrollable gelling kinetics by injecting in vivo, which limit their applications [2].
A novel furyl-modified polyurethanes hydrogel is synthesized for developing
injectable degradable hydrogel using crosslinker maleimide-terminated PEG. In the
polyurethane, PEG shows good hydrophilicity and the functional modification of
chain extender endows the hydrogel with expected injectable gelling. The mechanical
strength and gelling time of crosslinked polyurethanes hydrogel could be improved by
adjusting the molar ratio of furyl to maleimide. The hydrogel obtains comprehensive
mechanical properties and favorable injectability. The work proposes a novel strategy
to constructing self-assembly polyurethane micelles before spontaneous gelation. This
injectable and biodegradable crosslinking hydrogel holds great potential application
for 3D cell culture and tisse repair.
Keywords: Biodegradable, Injectable hydrogel, Diels-Alder reaction, Cell
encapsulation, Polyurethanes.
References:
[1]. Smith LJ.; Taimoory SM.; Tam RY.; Aeg B.; Binth MN.; Trant JF*,
Biomacromolecules. 2018, 19, 926.
[2] Yang X.; Liu G.; Peng L.; Guo J.; Tao L.; Yuan J.; Lina Z*, Adv. Funct. Mater.
2017, 27,1703174
This research was supported by the National Natural Science Foundation of China (Grant No.
51873117, 51673126, 51733005), the National Science Foundation For Distinguished Yong
Scholars of China (51425305).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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Shape memory hydrogel based on sodium alginate crosslinked by
double networks
Xudong He1*, Hongmei Chen1, Ping Hu1
(1 College of Chemistry and Materials Science , Sichuan Normal University,
Chengdu 610066, P. R. China)
*E-mail: [email protected]
Sodium alginate has attracted wide attentions for its excellent biocompatibility
and biodegradability.[2-3] Smart hydrogels based on sodium alginate can be applied in
the fields of gene delivery, tissue engineering, drug controlled release, wearable soft
materials, etc. But the single-function nature, slowly response and low strength of
traditional hydrogels restricted its applications. A dual networks hydrogel based on
sodium alginate crosslinked by glutaraldehyde and calcium ion are prepared.[1]Tensile
testing showed that the mechanical strength of this hydrogel can reach 6.2 MPa. This
hydrogel showed excellent water-induced shape memory property by introducing
cellulose into the dual networks, and the shape fixing ratio and recovery ratio are
nearly 100%. For its excellent performance, this hydrogel can be applied as
cardiovascular stents, robotic muscles and wearable soft materials.[4]
Keywords: Sodium alginate hydrogels, Dual crosslinked networks, Water-induced
shape memory property.
References:
[1] Q. Chen, H. Chen, L. Zhu, J. Zheng, Fundamentals of double network hydrogels,
Journal of Materials Chemistry B 3 (2015) 3654-3676.
[2] Y. Vijaya, S.R. Popuri, A.S. Reddy, A. Krishnaiah, Synthesis and characterization
of glutaraldehyde-crosslinked calcium alginate for fluoride removal from aqueous
solutions, Journal of Applied Polymer Science 120 (2011) 3443-3452.
[3] H. Hecht, S. Srebnik, Structural Characterization of Sodium Alginate and Calcium
Alginate, Biomacromolecules 17 (2016) 2160-2167.
[4] Jiyu Yang, Yanan Zheng, Linjuan Sheng, Hongmei Chen,* Lijuan Zhao, Wenhao
Yu, Ke-Qing Zhao,and Ping Hu,Water Induced Shape Memory and Healing Effects
by IntroducingCarboxymethyl Cellulose Sodium into Poly(vinyl alcohol),Ind. Eng.
Chem. Res. 2018, 57, 15046−15053
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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P 1-27
Highly adhesive and stretchable photothermal hydrogels for
preventing postoperative recurrence of cancer
Wenwen Jiang, Rui Zhao, Liang Hu‡‡‡‡‡‡‡‡‡‡‡‡
(State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and
Protection, Soochow University, Suzhou 215123, China.)
*E-mail: [email protected]
Prevention of postoperative tumor recurrence is crucial to improve the survival
rate of patients.1 To address this, in-situ locating a photothermal hydrogel patch to the
resected tumor site is a simple, rapid and safe strategy. This required photothermal
hydrogels with high adhesion and stretchability, yet it is still a great challenge.2 In this
work, we constructed a poly(acrylamide-co-N-(3-aminopropyl)methacrylamide)
(p(AAm-co-APMA)) hydrogel that was crosslinked by polydopamine nanoparticles
(PDA NPs). The hydrogel showed high adhesive strength to a variety of substrates
(e.g., ~115 kPa to the porcine skin), stretchability (~3700%) and photothermal
property. These merits can be ascribed to the use of PDA NPs as crosslinkers and
numerous physical interactions (π-π interactions as well as the hydrogen bonds) in the
system. Finally, we showed that, upon exposure to 808 nm light within 3 min, the
p(AAm-co-APMA) photothermal hydrogel patch absorbed light and converted to
thermal, thereby effectively preventing postoperative recurrence of the breast cancer
in mice.
Keywords: Hydrogel, Adhesive, Stretchable, Photothermal therapy
References:
[1]. Mahvi, DA.; Liu, R.; Grinstaff, MW.; Colson, YL.; Raut, CP., Ca-Cancer J. Clin.
2018, 68, 488
[2]. Han, L.; Lu, X.; Liu, KZ.; Wang, KF.; Fang, LM.; Weng, LT.; Zhang, HP.; Tang,
YH.; Ren, FZ.; Zhao, CC.; Sun, GX.; Liang, R.; Li, ZJ., ACS Nano 2017, 11, 2561
This research was supported by the National Natural Science Foundation of China (Grant No.
51873137).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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Sulfonated MXene Nanocomposite Hydrogels for Self-healing,
Adhesive and Conductive Properties
Ze Peng Deng1, Yang He1, Yi Ping Zhao1, Li Chen1,2§§§§§§§§§§§§
(1 School of Materials Science and Engineering,Tianjin Polytechnic University, Tianjin, 300387.2
School of Materials Science and Engineering, Tianjin University of Technology, Tianjin, 300384)
*E-mail: [email protected]
Currently, self-healing, adhesive and conductive hydrogels have been
highlighted their potential in wearable electronic devices, soft robotics and tissue
engineering. Herein, we demonstrated a facile one-step synthesis method of
nanocomposite hydrogels incorporating sulfonated MXene (MXene-SO3H) by
ionotropic gelation of chondroitin sulfate (CS) and poly (methyl chloride quarternized
N, N-dimethylamino ethylacrylate) (PDMAEA-Q). Owing to the abundant
electrostatic interaction between the multivalent anionic CS and cationic PDMAEA-Q,
the hydrogel matrix revealed a rapid and reversible self-healing property (within 2s)
without any assistance of external stimuli. The nanocomposite hydrogels displayed
robust adhesiveness ascribed to the presence of glycosaminoglycan ingredients from
the CS, which can be adhered directly on porcine skin with excellent biocompatibility.
Meanwhile, the stable dispersive 2D MXene-SO3H nanosheets were well-integrated
with the polymer network, which endowed the hydrogels conductivity. The
fascinating physical properties of the MXene facilitated high sensitivity to
deformation, near-infrared light and humidity in the nanocomposite hydrogels.
Consequently, the combination of these properties enables the nanocomposite
hydrogels to act as biosensors in wearable, wireless, and soft electronics for
human-machine interfaces, human activity monitoring, personal healthcare diagnosis,
etc.
Keywords: Nanocomposite hydrogel, MXene, Self-healing, Conductivity, Sensor
References:
[1]. Sun TL.; Kurokawa T.; Kuroda S.; Ihsan AB.; Gong JP., Adv. Funct. Mater.
2013, 12(10): 932
This research was supported by the Science and Technology Plans of Tianjin (18PTSYJC00180),
Program for Innovative Team in University of Ministry of China (IRT-17R80).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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Research on Gel Analyzer Based on Image Processing
Xiaojuan Ren, Rui Wang, Saqib Siddique
(College of Petroleum Engineering, Xi’an Shiyou University,Xi’an 710065)
*E-mail: [email protected]
As a chemical plugging and plugging agent, gel plays an important role in crude
oil recovery and oil and gas recovery. The mechanical properties of gel are of great
importance to the quality of oil well plugging. At present, there is no system for
detecting the mechanical properties of Water Plugging Gel in the market, and most of
the products on the market rely on foreign imports, and the price is more expensive.
Therefore, through full investigation and research, a set of high precision and high
reliability gel mechanical properties measurement system is developed by using
digital image processing technology in order to solve the problem of low detection
precision in the process of gel mechanical properties detection.
The entire analysis system is composed of two major modules: displacement
pump pressurization unit and machine vision unit. The software system is based on
the modular programming language. The core of the analysis of gel mechanical
properties is image processing. For the basic characteristics of capillary gel images,
the gel image is first targeted for preprocessing and then a novel adaptive threshold
segmentation algorithm is proposed to obtain a more accurate capillary gel concave
surface. Finally, the gel concave surface is completely extracted to obtain the position
parameters of the gel concave surface and then combined with fluid mechanics theory
to calculate the mechanical properties of the oil field production requirements. All
data and images in the experiment will be stored in the database for the convenience
of testers. In order to improve the accuracy of the instrument, this paper analyzes the
most important mechanical properties of the gel: the possible error sources in the
viscosity measurement process and then the machine vision unit program is improved
to make the instrument more mature and the measurement system has a higher degree
of automation.
After completing the design and construction of the smart gel analysis system,
five different concentrations of gel samples were selected and compared with the
results of a rotary rheometer. The tests showed that for the five gel samples, two
measurements were performed. The measurement error between the methods is
relatively small and remains within 5%. It is proved that the measurement system of
gel mechanical properties studied in this paper has certain feasibility and reliability.
Keywords: Gel, Digital image processing, Measurement system design
References: [1].Xiaojuan Ren, Xinwei Gao, Xiangrong Luo,etc.A device and method for evaluating the performance of gel: China, ZL201611189905.3 [P]. 2017-11-14. [2].Yunzhou Ye. Research on Gel Analyzer Based on Image Processing[D]. Xi’an Shiyou University,2018.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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P 1-30
Preparation of keratin-based polymer hydrogel with double
sensitivity for drug releasing
Yujuan Wei, Rong-Min Wang*************, Juhua Guo, Zejun Wang, Yufeng He
(Key Lab. Eco-Environment-Related Polymer Materials of Ministry of Education, Institute of
Polymer, Northwest Normal University, Lanzhou 730070, China.)
*E-mail: [email protected]
In past decades, the intelligent polymers had been paid extensive attention as
stimulus-responsive polymer materials can transport drugs or bioactive substances
effectively. Keratin, being extracted from feathers, has good biocompatibility,
degradability and low immunity. And it can be used in all aspects of biomedicine[1,2].
In this paper, feather keratin (FK) was used as biopolymer substrate, itaconic acid (IA)
and N-isopropylacrylamide, as non-toxic and stable units, were selected as pH
sensitive monomers and temperature-sensitive monomers. The keratin-based polymer
hydrogel with double sensitivity were prepared in the presence of crosslinking agent.
Firstly, poly(N-isopropylacrylamide) was combined with FK. Then, IA was in-situ
polymerized, which afforded FK-based double sensitive polymer hydrogel with
interpenetrating network structure. In order to evaluate the suitability of FK-based
hydrogels as biomaterials, we measured the swelling rate of the double-sensitive
hydrogels in different simulated biological solutions at body temperature. The results
showed that the FK-based hydrogels has higher swelling rate and good swelling
performance in water, D-Glu solution and saline solution. Using small molecular and
macromolecular drug, its release behaviors were studied in different temperatures and
pH medium. The result indicated that the drugs controlled release from hydrogels
could be realized by adjusting temperature and pH value.
Keywords: Biopolymer gel, Feather keratin, Double sensitive, Drug release
References:
[1] Yin XC; Li FY; He YF., Wang Y; Wang RM, Biomater. Sci., 2013, 1(5), 528.
[2] Shavandi A; Silva TH; Bekhit AA; Bekhit AEDA, Biomateri Sci., 2017, 5(9),
1699.
This research was supported by the National Natural Science Foundation of China (Grant No.
21364012, 21865030).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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P 1-31
Facile preparation and enhanced stretchableperformance of
self-assembled polyelectrolytes-based composite hydrogels
Ran Wang1,2,Tifeng Jiao1,2*, Lexin Zhang2,Qiuming Peng1,*
(1State Key Laboratory of Metastable Materials Science and Technology, Yanshan University,
Qinhuangdao 066004, P. R. China; 2Hebei Key Laboratory of Applied Chemistry, School of
Environmental and Chemical Engineering, Yanshan University, Qinhuangdao 066004, P. R.
China.)
*E-mail: [email protected](T. Jiao);[email protected] (Q. Peng).
Hydrogels attract a great attention due to their soft and moist properties, but the
preparation of hydrogels with good mechanical properties requires further
investigation. In this study, we reported the preparation of polyelectrolytes-based
polyion complexes (PIC) hydrogel polymerized sequentially via two monomers with
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
123
cationic and anionic groups and subsequent several composite hydrogels. The PIC
hydrogel was doped with graphene oxide (GO), carbon nanotubes (CNTs) and layered
double hydrotalcites (LDHs) with different weight ratios, respectively. The structures
and changes of mechanical properties of the formed composite hydrogels were
investigated by SEM, BET, nanoindentation and strain-stress tests. We also studied
the dye adsorption capacities of the prepared hydrogels for MB and RhB, and the
doped composite hydrogels showed different adsorption properties compared to the
original PIC hydrogel. Present work demonstrated new clue to prepare composite
hydrogel materials with enhanced mechanical properties and promoted wide
applications.
Keywords: Composite hydrogel, Component doping, Mechanical properties,
Adsorption
References:
[1] Hou CL.; Jiao TF.; Xing RR.; Chen Y.; Zhou JX.; Zhang LX, J. Taiwan Inst.
Chem. E. 2017, 78, 118-126.
[2] Guo R.; Jiao TF.; Li RF.; Chen Y.; Guo WC.; Zhang LX.; Zhou JX.; Zhang QR.;
Peng QM, ACS Sustain. Chem. Eng. 2018, 6, 1279-1288.
[3] Zhu K.; Jiao TF.; Zhang LX.; Xing RR.; Guo R.; Zhou JX.; Hou CL.; Zhang QR.;
Peng QM.; Li X, Sci. Adv. Mater. 2016, 8, 1400-1407.
-------------------------------------------
This research was supported by the National Natural ScienceFoundation of China (Grant No.
21872119), Support Program for the Top Young Talents of Hebei Province, and Research Program
of the College Science & Technology of Hebei Province (No. ZD2018091).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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Tough, antibacterial and antifouling double network hydrogels based
on hybrid ionic-covalent crosslinking*
Zhang Jing * , Shen Biao, Chen Lingdong, Feng Jie
College of Materials Science and Engineering, Zhejiang University of Technology, Hangzhou,
Zhejiang, 310014, P. R. China
* Email:[email protected]
Due to their self-healing ability and fatigue resistance, hybrid ionically-covalently
crosslinked double-network (DN) hydrogels have received widely attention 1 . By a
simple “one-pot” method, a novel kind of hybrid ionic-covalent
chitosan/polysulfobetaine (CS/PSBMA) double-network hydrogels was synthesized.
The obtained DN hydrogels exhibit high tensile strength (2.0 MPa), strong elastic
modulus (0.5 MPa), fast self-recovery ability, and excellent antifatigue capacity.
Notably, the hydrogels still remain mechanical strength and toughness after soaking in
water for 24 h. More excitingly is that the hybrid DN hydrogels have excellent
antibacterial, antifouling properties and biocompatibility. We believe that the hybrid
DN hydrogels will find potential applications in biomedical applications, such as
artificial cartilage.
Figure 1. (A) Preparation of hybrid ionic-covalent CS/PSBMA DN gels using the “one-pot”
method. (B) H&E staining images of the CS/PSBMA DN hydrogel implanted subcutaneously in
mice for 28 days.
Keywords: Double network hydrogel, High mechanical properties, Biocompatibility,
Antibacterial, Antifouling
References:
[1]. Yang Y, Wang X, Yang F, et al. Advanced Materials, 2018:1707071.
-------------------------------------------
This work was funded by Zhejiang Provincial Natural Science Foundation of China
(LY17E030005) and the National Natural Science Foundation of China (21404091).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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P 1-33
Double cross-linking the second network of DN hydrogel for tough
sensitive strain and pressure sensors
Lin Jie Zhou1*, Jun Fu1
(1Ningbo Institute of Materials Technology & Engineering, Chinese Academy of Sciences, 1219
Zhongguan West Road, Ningbo 315201, China.)
*E-mail: [email protected]
Hydrogels, characterized for high water content and three-dimension network,
have attracted much attention owing to their broad potential applications as
cartilages1-2, scaffolds3, actuators4-6 and soft sensors7-8, etc. Specifically, conductive
hydrogels, as soft, flexible and biocompatible conductor are promising materials for
electronic skins9 or implantable sensors10 to detect human physiological and physical
signals. Based on the dynamic metal-coordination, here, we report a
κ-carrageen/P(AAm-co AAc) DN hydrogel based on biopolymer κ-carrageen with
outstanding mechanical properties. Fe3+ ions were used to further crosslink the second
network by forming coordination complex with carboxyl groups in AAc. Hydrogels
with different content of coordination complex exhibit excellent mechanical
performance with fracture tensile stress of 0.47~1.52 MPa, fracture strain of
160~2800%. The hydrogels show good electrical fatigue resistance and high
sensitivity of 2.8 at 500% strain which performance well in strain and pressure sensors
for practical applications.
Keywords: Hydrogel, Toughness, Conductivity, Sensor
References:
1. Adams, M. A.; Kerin, A. J.; Wisnom, M. R., Sustained loading increases the
compressive strength of articular cartilage. Connective Tissue Research 1998, 39 (4),
245-256.
2. Naficy, S.; Brown, H. R.; Razal, J. M.; Spinks, G. M.; Whitten, P. G.,
ChemInform Abstract: Progress Toward Robust Polymer Hydrogels. Cheminform
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
126
2015, 43 (2), 1007-1025.
3. Hoffman, A. S., Hydrogels for biomedical applications. Annals of the New York
Academy of Sciences 2012, 64 (1), 18-23.
4. Maeda, S.; Hara, Y.; Sakai, T.; Yoshida, R.; Hashimoto, S., Self-Walking Gel.
Advanced materials 2007, 19 (21), 3480-3484.
5. Yao, C.; Liu, Z.; Yang, C.; Wang, W.; Ju, X. J.; Xie, R.; Chu, L. Y.,
Poly(N‐isopropylacrylamide)‐Clay Nanocomposite Hydrogels with Responsive
Bending Property as Temperature‐Controlled Manipulators. Advanced Functional
Materials 2015, 25 (20), 2980-2991.
6. Shin, M. K.; Spinks, G. M.; Shin, S. R.; Kim, S. I.; Kim, S. J., Nanocomposite
Hydrogel with High Toughness for Bioactuators. Advanced materials 2009, 21 (17),
1712-1715.
7. Son, D.; Bao, Z., Nanomaterials in Skin-Inspired Electronics: Toward Soft and
Robust Skin-like Electronic Nanosystems. ACS nano 2018, 12 (12), 11731-11739.
8. Wang, L.; Gao, G.; Zhou, Y.; Xu, T.; Chen, J.; Wang, R.; Zhang, R.; Fu, J., Tough,
Adhesive, Self-Healable, and Transparent Ionically Conductive Zwitterionic
Nanocomposite Hydrogels as Skin Strain Sensors. ACS Applied Materials &
Interfaces 2019, 11 (3), 3506-3515.
9. Yang, T.; Wang, W.; Zhang, H.; Li, X.; Shi, J.; He, Y.; Zheng, Q.-s.; Li, Z.; Zhu,
H., Tactile Sensing System Based on Arrays of Graphene Woven Microfabrics:
Electromechanical Behavior and Electronic Skin Application. ACS nano 2015, 9 (11),
10867-10875.
10. Han, L.; Lu, X.; Wang, M.; Gan, D.; Deng, W.; Wang, K.; Fang, L.; Liu, K.; Chan,
C. W.; Tang, Y.; Weng, L.-T.; Yuan, H., A Mussel-Inspired Conductive, Self-Adhesive,
and Self-Healable Tough Hydrogel as Cell Stimulators and Implantable Bioelectronics.
Small 2017, 13 (2), 1601916.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
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P 1-34
Synthesis and swelling properties of superporous anionic hydrogel
based polyvinyl alcohol-formaldehyde sponges
Jiuduo Xu, Xu Yang, Di Sha, Kai Shi, Baolong Wang, Xiangling Ji*
(Key State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied
Chemistry, Chinese Academy of Sciences, Changchun 130022, China)
*E-mail: [email protected]
Superporous hydrogels (SPHS) are developed from superabsorbent
polymers(SAPs) with swell faster, within mimutes, to the equilibrium swollen and
faster response to environmental change. A series of superporous anionic hydrogels
(SPAHs) containing sodium carboxylate groups were synthesized by acetalization
reaction used of aldehyde crossing with modified poly(vinyl alcohol-co-vinyl acetate).
Through control the concentration of reactants and surfactants and the stirring rate
systematically the interconnected open cellular structure can be obtainted in the
superporous hydrogels. FITR and 13C NMR demonstrated that (SPAHs) was
successfully synthesized via acetalization reaction and carboxyl contents can be
controlled by changing experimental conditions. A typical interconnected open
cellular structure was observed by scanning electron microscopy. The as-prepared
hydrogels exhibited a mean pore sizes ranging from 60 to 100μm, and an
interconnected pores having a porosity of around 90%. The PVF-based hydrogel
possessed excellent mechanical property in dry state and swelling capacity in wet
state. Notably, the SPAHs can absorb deionized water as high as 130 g g-1 within 90 s
and can also absorb saline solution at a maximum capacity of 38 g g-1 in 120 s. The
sponges were characterized by their dynamic swelling behavior in solvent, ie the mass
of water absorbed by a sample of sponges was measured vs time and the kinetics of
the adsorption process was studied. And then the appropriate model was used
expected to possess accurate predictive ability for the diffusion coefficient of solute in
hydrogel, which will be widely used in the biomedical, chromatographic separation,
absorber, etc. field.
Keywords: PVA, Superporous anionic hydrogel, Swelling properties,
Diffusion-relaxation model
References:
[1]. Rosa F, Bordado J, Casquilho M. Polymer, 2002, 43(1): 63-70.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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P 1-35
Biotribology behavior of UHMWPE grafted with PVA/HA composite
hydrogel as artificial cartilage materials
Kai Chen, Siyu Liu, Fengyan Wang
School of Materials Science and Engineering, China University of Mining and Technology,
Xuzhou 221116, China
Abstract: The human body joint motion is very complicated, which mainly includes
sliding, swing, rotation. Therefore, cartilage covering the joint surface bears the
repeated friction which is caused by the different movements during the whole life. So
sliding, swing and torsion friction behavior of hydrogels need to be researched as
synthetic articular cartilage. In this paper, PVA/HA composite hydrogel is cross-linked
on the UHMWPE surface through chemical grafting and freezing-thawing method.
Biotribology behavior and fluid load support are researched. The results show that
swing and torsion friction coefficients are negligibly small, while sliding friction
coefficient is largest. There is a negative linear relationship between fluid load support
and friction coefficient. Fluid load supports are relative high under swing and torsion
friction, so the swing and torsion friction coefficients are relative low. Hydrogel can
be replenished by re-swelling to sustain the fluid pressurization during friction under
lubrication condition. Both fluid load support and biphasic lubrication due to its
porous structure with large amount of water contribute to the low friction coefficient.
Keywords: PVA/HA composite hydrogel; fluid load support; biotribology; lubrication
Fig 1 Relationship of friction coefficient Fig 2 Relationship of friction coefficient
and load under different movement modes and fluid load support under different movement modes
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
129
Fig 3 Relationship of friction coefficient Fig 4 Relationship of friction coefficient
and speed under different movement modes and fluid load support under different movement modes
Acknowledgements
This research is supported by National Natural Science Foundation of China (Grant
No. 51705517, 51875564), Natural Science Foundation of Jiangsu Province (Grant
No. BK20160257), National Key Research and Development Program of China
(Grant No. 2016YFC1101803).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
130
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Internal Damage Evolution in Double-Network Hydrogels Studied by
Microelectrode Technique
Honglei Guo1,2, Wei Hong3,2,4, Takayuki Kurokawa1,2, Takahiro Matsuda5, Zi Liang
Wu1,6, Tasuku Nakajima1,2,7, Taolin Sun1,2,8, Ping Rao5, Jian Ping Gong*1,2,7
(1Faculty of Advanced Life Science, 2Soft Matter GI-CoRE, Hokkaido University, Sapporo, Japan;
3Department of Mechanics and Aerospace Engineering, Southern University of Science and
Technology, Shenzhen, 518055, China; 4Department of Aerospace Engineering, Iowa State
University, Ames, Iowa 50011, United States; 5Graduate School of Life Science, Hokkaido
University, Sapporo, 001-0021, Japan; 6Ministry of Education Key Laboratory of Macromolecular
Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang
University, Hangzhou 310027, China; 7Institute for Chemical Reaction Design and Discovery
(WPI-ICReDD), Hokkaido University, N21W10, Kita-ku, Sapporo, Hokkaido, 001-0021, Japan;
8South China Advanced Institute for Soft Matter Science and Technology, South China University
of Technology, Guangzhou 510640, China)
E-mail: [email protected]
The double-network (DN) hydrogels have been drawn much attention in the field
of soft materials for their high mechanical strength and toughness.1 However, the
microstructure and morphology evolution of the internal damage in a DN gel has
hardly been revealed. Recently, we succeeded in applying microelectrode technique
(MET) for detecting electrical potential and its spatial distribution of brittle
polyelectrolyte hydrogels.2 In this study, we study the internal structures of the first
network in partially damaged DN gels by using MET, based on the Donnan effect of
the polyelectrolyte first network. We measure the spatial distribution of the electric
potential of the pre-stretched and then re-swollen DN gels. From the anisotropic depth
profiles of potential and re-swelling ratio, the microstructures of DN gels are revealed
at the pre-yielding, yielding, and strain-hardening regimes.
Keywords: DN hydrogels, internal damage, microelectrode technique, Donnan
potential
Reference:
[1] Gong, J. P.; Katsuyama, Y.; Kurokawa, T.; Osada, Y. Double-Network Hydrogels
with Extremely High Mechanical Strength. Adv. Mater. 2003, 15 (14), 1155–1158
[2] Guo, H.; Kurokawa, T.; Takahata, M.; Hong, W.; Katsuyama, Y.; Luo, F.; Ahmed,
J.; Nakajima, T.; Nonoyama, T.; Gong, J. P. Quantitative Observation of Electric
Potential Distribution of Brittle Polyelectrolyte Hydrogels Using Microelectrode
Technique. Macromolecules 2016, 49 (8), 3100–3108
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
131
P 1-37
Programmed deformations of 3D printed tough physical hydrogels
with metal-coordination complexes
Si Yu Zheng1, Yangyang Shen2, Jin Qian3, Jun Yin2, Zi Liang Wu1*, Qiang Zheng1
(1 Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027,
China; 2 School of Mechanical Engineering, Zhejiang University, Hangzhou 310027, China; 3
Department of Engineering Mechanics Zhejiang University, Hangzhou 310027, China.)
*E-mail: [email protected]
Shape morphing hydrogels have emerging applications in biomedical devices,
soft robotics and so on. However, successful applications require a combination of
excellent mechanical properties and fast responding speed, which are usually a
trade-off in hydrogel-based devices. Here we describe a facile approach to fabricate
three-dimensional (3D) gel constructs by 3D printing of tough physical hydrogels,
which showed programmable deformations with high response speed and large output
force. Highly viscoelastic poly(acrylic acid-co-acrylamide) (P(AAc-co-AAm)) and
poly(acrylic acid-co-N-isopropyl acrylamide) (P(AAc-co-NIPAm)) solutions or their
mixtures were printed into 3D constructs by using multiple nozzles, which were
transferred into FeCl3 solution for forming robust carboxyl-Fe3+ coordination
complexes. The printed gels containing PNIPAm segment or not exhibited different
responsiveness in concentrated saline solution. The mismatch in response afforded the
combined 3D gel constructs the ability of shape morphing, which can be deformed
into rolls, tubes, and cylinder helices. Because of the small diameter of gel fibers, the
deformation and recovery were completed within 1 min. A four-armed gripper was
designed with holding force as high as 115 times the weight of the gripper. This
strategy should broaden the applications of tough hydrogels toward a diversity of
self-shaping materials with outstanding mechanical properties and fast response.
Keywords: Toughness, 3D printing, Controllable deformation, Fast response
References:
[1]. Zheng SY; Shen Y; Zhu F; Yin J; Qian J; Fu J.; Wu ZL; Zheng Q, Adv. Funct.
Mater. 2018, 28, 1803366.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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P 1-38
Programmed multi-stable configurations of composite hydrogels with
in-plane and through-thickness gradients
Chen Yu Li1, Wei Hong2, Zi Liang Wu1*, Qiang Zheng1
(1Department of Polymer Science and Engineering, Zhejiang University Hangzhou 310027,
China; 2Department of Mechanics and Aerospace Engineering, Southern University of Science
and Technology, Shenzhen 518055, China)
*E-mail: [email protected]
Morphing materials have promising applications in various fields, and program
of complex configurations has been realized by incorporating different structures with
through-thickness gradient or different responsive materials. However, how to obtain
multiple configurations at the same condition, i.e. multi-stable configurations, still
remains a challenge. In-plane gradient-induced out-of-plane buckling has been studies
theoretically and experimentally. Owing to the absence of through-thickness gradient,
buckling unit has two possible configurations with equal probability, which can be
controlled by a pre-swelling process. In-plane gradient is integrated with
through-thickness one to obtain programmable and controllable complex 3D
configurations by photo-patterning high-swelling
poly(acrylamide-co-2-acrylamido-2-methylpropanesulfonic acid) (P(AAm-co-AMPS))
in non-swelling polyacrylamide (PAAm) gel. Therefore, integrating multiple (n)
buckling units will afford the composite hydrogel multiple (2n) configurations. This
work provides a concept to program complex composite hydrogels with multi-stable
configurations at one condition, which will benefit the development of intelligent
devices and robotics.
Keywords: Hydrogel, Morphing structures, Programmed deformation, In-plane
gradient, Multi-stability
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
133
P 1-39
Mechanical Property of Polyelectrolyte Networks
Ao-kai Zhang
Changzhou Vocational Institute of Light Industry, Changzhou 213164, China
*E-mail: [email protected]
Structure-property relationship of polyelectrolyte networks is a issue long under
debate due to the complex interplay of microscopic short and long range interactions.
Here we perform molecular dynamics simulations to obtain the equilibrium and
mechanical properties of polyelectrolyte networks as a function of chain length and
electrostatic strength(including bjerrum length and ion valency). We find that
maximum strain of polyelectrolyte network is controlled by electrostatic strength,
which determines chain extension. Maximum stress scales with chain length, and is
also affected by electrostatic force. Our results provide a versatile tool for predicting
mechanical property of polyelectrolyte networks.
Keywords: Gel, Molecular dynamics, Toughness, Polyelectrolyte
References:
[1]. Mann BA.; Holm C.; Kremer K., The Journal of Chemical Physics. 2005, 122,
154903
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
134
P 2-1
Adhesive, self-healable, and transparent micro-crosslinked
organogels as flexible sensor
Zhi Xing Zhang, Fei Zhang, Lin Tang, Wei Feng
(School of Materials Science and Engineering, Tianjin University, Tianjin Key Laboratory of
Composite and Functional Materials, Tianjin 300072, P.R China.)
E-mail: [email protected]
Gel materials with liquid as dispersing medium have great potentials for
applications in electronic skin, biomedical sensors, soft robotics, and so on [1,2].
However, traditional hydrogels are easy to lose water and thus lose elasticity, which
largely limit their applications [3]. Hence, organogels are developed for addressing the
above drawbacks [4]. A series of organogels based lauryl acrylate are designed, which
possess novel comprehensive performances, including mechanical adaptation,
self-healability, self-adhesion and high transparency. We demonstrate this organogel
combined with conductive materials as a pressure sensor to exhibit stable operation
after repeated loadings. Meanwhile, the resulting sensor also can be sensitive toward
temperature and strain. This work provides a new design concept to fabricate flexible
sensors, which might not only show great potential in applications such as artificial
intelligence, human/machine interactions, personal healthcare, and wearable devices,
but also promote the development of next-generation mechanically adaptable
intelligent skin-like devices.
Keywords: Organogels, Self-healability, Self-adhesion, Flexible sensor
References:
[1]. Rong QF.; Lei W.; Liu MJ*, Chem-Eur. J. 2018, 24, 16930-16943.
[2] Yuk H.; Lu B.; Zhao X*, Chem. Soc. Rev. 2019, 48, 1642-1667.
[3] Zhao T.; Wang G.; Hao D.; Chen L.; Liu K.; Liu M*, Adv. Funct. Mater. 2018,
28, 1800793.
[4] Xie W.; Duan J.; Wang H.; Li J.; Liu R.; Yu B.; Zhou J*, J. Mater. Chem. A
2018, 6, 24114-24119.
This research was supported by the National Natural Science Foundation of China (Grant No.
51803149).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
135
P 2-2
Highly Stretchable, Electrically Conductive and Temperature
Tolerant Ionogels for Flexible Sensors
Jialiang Lai, Hongwei Zhou†††††††††††††
(School of Materials and Chemical Engineering, Xi'an Technological University, Xi'an, 710021,
P. R. China)
*E-mail: [email protected]
Highly stretchable, electrically conductive and temperature tolerant ionogels
have been constructed by crosslinking polymeric matrixes with macromolecular
cross-linkers. Poly(acrylic acid) (PAA) network cross-linked by double-bond
end-capped Pluronic F127 (F127DA) is selected as the flexible matrix, and
1-ethyl-3-methylimidazolium dicyanamide ([EMIm][DCA]) is physically locked in
the PAA network as the conductive and temperature tolerant component. The
resulting ionogels are highly stretchable (>850%), tough and fatigue resistant, and
they are also conductive (1.9 S m−1), transparent (>85%) and temperature tolerant. On
the basis of the PAA ionogels, resistive-type sensors and capacitive-type sensors are
assembled and further applied in monitoring large human motions and subtle
physiological activities, including moving of two hands, bending of joints, moving of
the bicipital muscle, breathing, swallowing and touching. It is believed that such
ionogels may find potential applications not only in sensors, but also in other devices
such as flexible supercapacitors, transistors, batteries and actuators.
Keywords: Ionogel, flexible sensor, high stretchability, ionic liquid, Pluronic F127
References:
[1] Z. W. Wang, H. W. Zhou,* J. L. Lai, B. Yan, H. B. Liu, X. L. Jin, A. J. Ma, G.
Zhang, W. F. Zhao and W. X. Chen, Extremely stretchable and electrically conductive
hydrogels with dually synergistic networks for wearable strain sensors, Journal of
Materials Chemistry C, 2018, 6, 9200-9207.
[2] Z. W. Wang, H. W. Zhou,* W. X. Chen, Q. Z. Li, B. Yan, X. L. Jin, A. J. Ma, H.
This work was supported by the National Natural Science Foundation of China (No. 51603164),
Natural Science Basic Research Plan in Shaanxi Province of China (Nos. 2016JQ5036,
2019JM-124)
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
136
B. Liu and W. F. Zhao, Dually Synergetic Network Hydrogels with Integrated
Mechanical Stretchability, Thermal Responsiveness, and Electrical Conductivity for
Strain Sensors and Temperature Alertors, ACS Applied Materials & Interfaces,
2018, 10, 14045-14054.
[3] J, L, Lai; H. W. Zhou,* M.C. Wang, Y. K. Chen, Z.Y. Jin, S. L. Li, J. J. Yang, X.
L. Jin, H. B. Liu, W.F. Zhao, Recyclable, stretchable and conductive double network
hydrogels towards flexible strain sensors, Journal of Materials Chemistry C, 2018,
6, 13316-13324.
[4] H. W. Zhou,∗ X. L. Jin, B. Yan, X. J. Li, W. Yang, A. J. Ma, X. H. Zhang, P. Li,
X. B. Ding, W. X. Chen,* Mechanically Robust, Tough, and Self-Recoverable
Hydrogels with Molecularly Engineered Fully Flexible Crosslinking Structure,
Macromolecular Materials & Engineering, 2017, 302, 1700085.
[5] H. W. Zhou,∗ M. Zhang, J. C. Cao, B. Yan, W. Yang, X. L. Jin, A. J. Ma, W. X.
Chen, X. B. Ding, G. Zhang, Highly Flexible, Tough, and Self-Healable Hydrogels
Enabled by Dual Cross-Linking of Triblock Copolymer Micelles and Ionic
Interactions, Macromolecular Materials & Engineering, 2017, 302, 1600352.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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P 2-3
A Shorter Alkyl Chain Dominated Self-Assembly of Homochiral
Nanotubes in Heterochiral Lipid Organogels
‡‡‡‡‡‡‡‡‡‡‡‡‡Xuefeng Zhu‡1, Yuqian Jiang‡2, Dong Yang1, Li Zhang1, Yuangang Li1,
Minghua Liu1*
(1Beijing National Laboratory for Molecular Science (BNLMS), CAS Key Laboratory of Colloid
Interface, and Chemical Thermodynamics, Institute of Chemistry, Chinese Academy of Sciences,
Beijing 100190, P. R. China; 2National Center for Nanoscience and Technology, Beijing 100190, P.
R. China)
*E-mail: [email protected]
It is important to achieve homochiral materials from a molecular, supramolecular
level to nanoscale and mesoscopic dimension. While it has been regarded that the
“majority rule” guides the homochiral self-assembly of enantiomer mixtures, it still
remains a big challenge to manipulate homochirality in a complex system. In this
report, a new case deviated from the “majority rule” was demonstrated, wherein
homochiral nanotubes self-assembled from a mixture of heterochiral lipids through an
alcoholic gelation process. When two heterochiral lipids with mirror head but a
2-methylene discrepancy in alkyl tail are mixed, homochiral nanotubes are always
formed regardless of their mixing ratio. The tubular helicity is exclusively controlled
by the molecular chirality of the shorter lipids. MD simulation further reveals that the
match of both the alkyl chain length and hydrogen-bonding between two heterochiral
lipids plays an important role in the cooperative self-assembly. This work offers a
new insight into supramolecular chirality and guidance in exploring homochiral
materials in complex self-assembly systems including supramolecular gels.
Keywords: Chirality, Self-Assembly, Lipid Nanotube, Gel, Complex System
References:
[1]. Palmans A.; Meijer E., Angew. Chem., Int. Ed., 2007, 46, 8948.
[2]. Perez-Garcia L.; Amabilino D., Chem. Soc. Rev., 2007, 36, 941.
[3]. Liu M.*; Zhang L.; Wang T., Chem. Rev., 2015, 115, 7304.
[4]. Zhu X.; Jiang Y.; Yang D.; Zhang L.; Li Y.; Liu M., Chem. Sci., 2019, 10, 3873.
This research was supported by the National Natural Science Foundation of China (21890734),
Strategic Priority Research Program of the Chinese Academy of Sciences (XDB12020200), and
Key Research Program of Frontier Sciences, CAS, (QYZDJSSW-SLH044).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
138
P 2-4
Anti-freezing, non-drying tough organohydrogel with good flexibility
and conductivity
Juan Li§§§§§§§§§§§§§
, Dongyang Lou, Xiaoyi Sun*
(College of Chemistry and Chemical Engineering, Central South University, 932 Lushan Road,
Changsha, Hunan 410083, China)
*E-mail: [email protected]; [email protected]
Recent progress of tough hydrogel has attracted a lot attention not only in
biomedicine, but also as soft electronic devices, sensors, and robotic actuators.
However, most of hydrogels lose their flexibility below the freezing point of water
and are easy to dehydrate in hot environment.
A novel double-network (DN) organohydrogel of PAMPS/PAAm, obtained by
solvent displacement from ethylene glycol solution of lithium salt, retains high
mechanical performance, flexibility and conductivity in the temperature range of
−80~120 oC. This work provides a new strategy to prepare flexible organohydrogels,
towards the fields of flexible electronic sensors.
Keywords: Gel, Flexibility, Conductivity, Toughness
References:
[1] Gong, J. P.; Katsuyama, Y.; Kurokawa, T.; Osada, Y., Adv. Mater. 2003, 15 (14),
1155-1158.
[2] Rong, Q.; Lei, W.; Chen, L.; Yin, Y.; Zhou, J.; Liu, M., Angew. Chem. Int. Ed.
2017, 56 (45), 14159-14163.
This research was supported by the National Natural Science Foundation of China (No. 21574147),
the Hunan Provincial Natural Science Foundation of China (No. 2018JJ2483) and the
Innovation-Driven Project of Central South University (No. 2017CX020).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
139
P 2-5
Organic or inorganic crystallization in functional molecular gels
Pan Han1, Kai Qiang Liu**************1, Yu Fang1
(1Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of
Chemistry and Chemical Engineering, Shaanxi Normal University, Xi’an 710119, P. R. China)
*E-mail: [email protected]
As a recently developed medium for crystal growth, molecular gels derived from
low-molecular-mass gelators (LMMGs), are a typical class of soft materials in which
gelator molecules can be assembled into dynamic three-dimensional networks via
cooperative supramolecular interactions. The gel matrix commonly entraps solvent
molecules and prevents the macroscopic flow of the solvent within its networks.
Therefore, the gel media suppress sedimentation or aggregation of the crystals and
prevent the arbitrary growths along faces in contact with the vessel walls. As proved,
the molecular gel acts as an inert matrix repressing heterogeneous nucleation and
making homogenous nucleation dominant or affords an activated gel structure
enhancing heterogeneous nucleation. The gel 3D network could provide spatial
confinements for the growth of 1D organic semiconductor crystals (e.g. fullerene, etc.)
along the directional dispersion of anti-solvent, or strong or weak couplings for
spatially confined growth of organic or inorganic crystals (organic semiconductor,
pharmaceuticals, and metal nanocrystals, etc.).
Keywords: Molecular gel, Crystal, Spatial confinement, Coupling effect
References:
[1]. Liu KQ.*; Gao S.; Zheng Z.; Deng XL.; Mukherjee S.; Wang SS.; Xu H.; Wang
JQ.; Liu JF.; Zhai TY.*; Fang Y*, Adv. Mater. 2019, 31, 1808254.
[2] Wang SS.; Liu KQ.*; Gao S.; Wang JQ.; Marella RK.; Fang Y*, Soft Matter 2017,
13, 8609.
[3] Gao S.; Wang SS.; Ma J.; Wu Y.; Fu XW.; Marella RK.; Liu KQ.*; Fang Y,
Langmuir 2016, 32, 12805.
[4] Kumar DK.; Steed JW*, Chem. Soc. Rev. 2014, 43, 2080.
This research was supported by the National Natural Science Foundation of China (Grant No.
21872091, 21473110).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
140
P 3-1
Oil-water separation, Lightweight, Flexible and Thermally-Insulating
Aerogels Derived from wood Nanofibrillated Cellulose
Yu Meng, Jianye Huang,Yanxiao Yang, Xuning Tan, Chenchen Dai, Qing Li*
(College of Materials Science and Engineering, Northeast Forestry University, Harbin150040,
China.)
*E-mail: liqing2016@ nefu.edu.cn
Nowadays, environmental pollution is becoming more and more serious. Organic
substances, oils and fats and various mixed pollutants have seriously affected people's
production and life. Therefore, it is extremely urgent to find a simple and effective
method to degrade pollutants. In the context of global consensus on renewable
resources, the rational development of wood resources has attracted the attention of
many researchers. The high-aspect-ratio wood-derived nanofibrillated cellulose (NFC)
was utilized as building blocks to construct aerogels. The wood NFC formed strong
web-like entangled structures that acted as the skeletal support of aerogels, exhibiting
a low density. The wood NFC aerogels (WoNAs) were soft, flexible, and illustrated
good resilience performance after compression release. The WoNAs had a high
oil-water separation capacity arising from the small aperture (diameter is 1∼10 nm)
and high aspect ratio of wood NFC, demonstrating their application suitability in
oil-water separation. In this paper, the mixture of soybean oil and distilled water is the
main oil-water separation object. Several NFC solutions with different concentration
gradients are prepared, and then sixteen different nanometer specifications are
prepared by freeze-drying method. Among them, the separation efficiency of aerogels
with the concentration of 0.5%-20ml is the best, which can achieve quickly oil-water
separation. The continuous oil-water separation performance of nanocellulose aerogel
shows that the 1975 ml oil-water mixture can be separated at one time with a
separation effect of 19515 g/g, which can be used for continuous separation of oils
and micro-nanoparticles. Further, the WoNAs exhibited an excellent thermal
insulating performance and insulation stability at various temperatures owing to their
porous structures and high thermal stability. The WoNAs fabricated herein are thus
expected to be a novel member of the filtration Separation Material owing to their
intrinsic characteristics attained by integrating multiple structural and performance
advantages into the one.
Keywords: Nanofibrillated cellulose, Aerogels, Flexibility, Oil-Water separation,
Thermal insulation
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
141
Fig.1 Comparisons of Experimental Devices and Digital Photos before and after
Oil-Water Separation: (a, b) Pictures before and after the separation of soybean
oil-water; (c, d) Pictures before and after the separation of petroleum-water;(e)
Oil-water separation rate curve;(f) Separation rate curve of aerogels under harsh
environment
Fig.2 Contact angle test results of WoNAs under HCl, NaOH, NaCl, hot water and ice
water conditions: (a) contact angles of aerogels and Dichloromethane under various
conditions; (b) contact angles of aerogels and Dichloroethane under various conditions;
(c) contact angles between aerogels and Carbon tetrachloride under various conditions
References:
[1]. Wang Y.; Uetani K.; Liu S.; et al. ChemNanoMat, 2016.
[2]. Gustafsson S J.; Mihranyan A.; ACS Applied Materials & Interfaces, 2016,
8(22):13759.
[3]. Gustafsson S.; Lordat P.; Hanrieder T.; et al. Mater. Horiz. 2016:10.1039.
[4]. Chen W.; Li Q.; Wang Y.; et al. ChemSusChem, 2014, 7(1): 154-161.
[5]. Wang Y.; Uetani K.; Liu S.; et al. ChemNanoMat, 2017, 3(2): 98-108.
[6]. Venkataraman M.; Mishra R.; Kotresh T M.; et al. Textile Progress, 2016, 48(2):
55-118.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
142
P 3-2
Preparation and characterization of ultra-fast
Temperature-responsive nanofibrous hydrogel
Xie Zheng, Liusheng Zha††††††††††††††
(State Key Laboratory for Modification of Chemical Fibers and Polymer Materials & College of
Materials Science and Engineering, Donghua University, Shanghai, 201620, China.)
*E-mail: [email protected]
As we know, one of the shortages of traditional temperature-responsive
hydrogels is their low response rate due to the dense skin layer formed on their
surfaces during their contraction process, which severely limits their applications in
the fields such as controlled drug release, sensor and actuator. Improvement of their
response rate has been attracting the attention of many researchers. In this work, a
ultra-fast temperature-responsive nanofibrous hydrogel was prepared by freeze drying
the dispersion of shortened electrospun poly(N-isopropylacrylamide-co-
N-hydromethylacrylamide) nanofibers in t-butanol, followed by heat treatment to
produce chemical linkages inside the nanofibers or between them. Its hierarchical
porous structure, observed by scanning electron microscope, consists of the major
pores with an average diameter of 43.8 μm and the minor pores with the one of 4.2
μm. When the environmental temperature is changed between 26 ℃ and 55 ℃, the
swelling equilibrium of the nanofibrous hydrogel can be achieved within 34 s.
Comparatively, the bulky poly(N-isopropylacrylamide) hydrogel of the same size
needs 1.1 h to achieve the equilibrium.
Keywords: Rapid response, Nanofibrous hydrogel, Temperature responsiveness
References:
[1]. Maeda S*; Kato T.; Kogure H.; Hosoya N, Appl. Phys. Lett. 2015, 106, 171909
[2]. Liu Z.; Wei J.; Faraj Y.; Ju XJ.; Xie R.; Wang W.; Chu LY*, Can. J. Chem. Eng.
2018, 96, 2100
[3]. Zheng X.; Liu XY.; Zha LS*, Macromol. Mater. Eng. 2019, 1900125
This research was supported by the National Natural Science Foundation of China (Grant No.
51373030).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
143
P 3-3
Cu/Cu2O/CuO Nanoparticles Loaded on Porous Carbon from a
Novel Hypercrosslinked Porous Polymer for Catalytic Reduction of
4-Nitrophenol
Xue sun, Xiao Li, Jiaojiao Mao, Caihong Li, Yuelin Yang, Weiying Zhang,
Xiaoguang Ying, Jianying Huang
(Fujian Key Laboratory of Advanced Manufacturing Technology of Special Chemicals, College of
Chemical Engineering, Fuzhou University, Quanzhou 362100, China.)
*E-mail: [email protected]
In the past several decades, the catalysts have been extensively investigated for
scientific and industrial applications. It is well known that agglomeration of catalysts
leads to the decrease of catalytic activity. Herein, a novel hypercrosslinked porous
polymer containing copper ions are first prepared by an external cross-linker using
β-cyclodextrin and tannic acid complexes as monomers. Then the Cu/Cu2O/CuO
heterostructural nanoparticles loaded on porous carbon framework for the catalytic
reduction of 4-nitrophenol are produced by pyrolysis of the hypercrosslinked porous
polymer. The copper-based catalyst nanoparticles are uniformly dispersed on the
porous carbon. With the loading of catalyst about 0.03 wt%, the turnover frequency
(TOF) for the conversion of 4-nitrophenol to 4-aminophenol can reach 0.758 mg/mg·s.
Therefore, the Cu/Cu2O/CuO@Carbon has high catalytic activity, and its preparation is
simple, which provides a new idea for the fabrication of supported catalysts.
Keywords: Hypercrosslinked porous polymers, Porous carbon, Copper catalyst,
4-nitrophenol
References:
[1] Davankov V A, Tsyurupa M P. Hypercrosslinked polymeric networks and
adsorbing materials: Synthesis, properties, structure, and applications[M]. Elsevier,
2011.
[2] Li B, Gong R, Wang W, et al. A New strategy to microporous polymers: Knitting
rigid aromatic building blocks by external cross-linker[J]. Macromolecules, 2011,
44(8): 2410-2414.
*This research was supported by the Natural Science Foundation of Fujian Province, China (Grant
No. 2019J01652) and the Science and Technology Project of Fuzhou, China (No.2018-G-67).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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P 3-4
Synthesis of leafy-shape TiO2-C nanosheets by alkaline treatment of
Ti3C2Tx MXene
Na Zhao1, Yang Hu1, Jinlong Du2, Jing Peng1, Maolin Zhai1‡‡‡‡‡‡‡‡‡‡‡‡‡‡.
( 1. Beijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation
Chemistry Key Laboratory of Fundamental Science, the Key Laboratory of Polymer Chemistry
and Physics of the Ministry of Education, College of Chemistry and Molecular Engineering,
Peking University, Beijing 100871, China.
2. State Key Laboratory of Nuclear Physics and Technology, School of Physics, Peking University,
Beijing 100871, P. R. China.)
*E-mail: [email protected]
MXenes is an emerging family of two-dimensional (2D) metal carbides,
carbonitrides and nitrides. Its general formula is Mn+1XnTx (M, X, and T stand for
transition metal, carbon/nitrogen, and surface terminations such as OH, O, and F,
respectively). Because of their high metallic conductivity and rich surface properties,
the Ti3C2Tx MXene are regarded as “hydrophilic graphene” or “conductive clay” [1],
which are potential materials to fabricate the 3D porous aerogels. MXene-sponge[2]
and MXene/graphene composite aerogels[3, 4] have been prepared for the applications
of supercapacitoers, piezoresistive sensor and so on.
Herein we prepared the amorphous TiO2-C nanosheets derived from Ti3C2Tx
MXene by a simple alkaline treatment at room temperature, which was confirmed by
the XPS and XRD. What’s more, the existence of oxygen vacancies of the amorphous
TiO2-C was confirmed by EPR spectroscopy with the g-value of 2.004[5, 6]. While in
the TEM images, we found that the alkaline treatment did not change the morphology
of Ti3C2Tx obviously. As shown in Fig.1a-c, the Ti3C2Tx nanosheets shows a uniform
2D leafy shape with a single layer and multilayers. After the alkaline treatment (Fig.
1d-f), the leafy shape was preserved in the alkalized Ti3C2Tx nanosheets, which are
mainly composed of multilayers. Base on the above analysis, we conceive that in this
structure, amorphous TiO2 with a large number of O vacancy is supported by 2D
planar carbon nanosheet. And due to the leafy shapes, abundant Oxygen vacancies
and high metallic conductivity, amorphous TiO2-C could be used for fabricating 3D
This research was supported by the Science Challenge Project (No. TZ2018004) and National
Natural Science Foundation of China (11575009, 11405168).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
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aerogel, which were further applied for photocatalysis material, electrode materials of
supercapacitor and lithium-ion batteries.
Keywords: Ti3C2Tx MXene, Alkaline treatment, Amorphous TiO2-C, Oxygen
vacancies.
Fig. 1. TEM images in different magnifications of: (a-c) pristine Ti3C2Tx nanosheets
before alkaline treatment, (d-f) corresponding as-treated Ti3C2Tx nanosheets.
References:
[1] Naguib, M.; Kurtoglu, M.; Presser, V.; Lu, J.; Niu, J.; Heon, M.; Hultman, L.;
Gogotsi, Y.; Barsoum, M. W., Two-dimensional nanocrystals produced by exfoliation
of Ti3AlC2. Adv. Mater. 2011, 23 (37), 4248-4253.
[2] Yue, Y.; Liu, N.; Liu, W.; Li, M.; Ma, Y.; Luo, C.; Wang, S.; Rao, J.; Hu, X.; Su,
J.; Zhang, Z.; Huang, Q.; Gao, Y., 3D hybrid porous Mxene-sponge network and its
application in piezoresistive sensor. Nano Energy 2018, 50, 79-87.
[3] Li, L.; Zhang, M.; Zhang, X.; Zhang, Z., New Ti3C2 aerogel as promising
negative electrode materials for asymmetric supercapacitors. J. Power Sources 2017,
364, 234-241.
[4] Ma, Y.; Yue, Y.; Zhang, H.; Cheng, F.; Zhao, W.; Rao, J.; Luo, S.; Wang, J.;
Jiang, X.; Liu, Z.; Liu, N.; Gao, Y., 3D synergistical MXene/reduced graphene oxide
aerogel for a piezoresistive sensor. ACS Nano 2018, 12 (4), 3209-3216.
[5] Fu, F.; Shen, H. D.; Sun, X.; Xue, W. W.; Shoneye, A.; Ma, J. N.; Luo, L.; Wang,
D. J.; Wang, J. G.; Tang, J. W., Synergistic effect of surface oxygen vacancies and
interfacial charge transfer on Fe(III)/Bi2MoO6 for efficient photocatalysis. Appl. Catal.
B-Environ. 2019, 247, 150-162.
[6] Liu, N.; Xu, M.; Yang, Y.; Zhang, S.; Zhang, J.; Wang, W.; Zheng, L.; Hong, S.;
Wei, M., Auδ−–Ov–Ti3 interfacial site: catalytic active center toward low-temperature
water gas shift reaction. ACS Catal. 2019, 9 (4), 2707-2717.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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P 3-5
Removal of Perrhenate using Radiation Synthesized Hierarchically
Macro/Mesoporous Silica-gratft-Quaternary Phosphonium
Xingxiao Li, Dong Han, Jing Peng, Jiuqiang Li and Maolin Zhai*
Beijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation Chemistry
Key Laboratory of Fundamental Science, the Key Laboratory of Polymer Chemistry and Physics
of the Ministry of Education, College of Chemistry and Molecular Engineering, Peking University,
Beijing 100871, China.
**E-mail:[email protected]
Keywords: Perrhenate, Radiation grafting, Hierarchically silica, Quaternary
phosphonium
Rhenium (Re) is one of the rare dispersed elements with the content of only 1
ppb in the earth crust. Due to the excellent properties of Re and Re alloys, they have
become one of the irreplaceable materials in modern high-tech fields, such as the
national defense, aerospace, petrochemical industry and so on. The demand for Re has
been rising recently, and the recycling of Re resources has become more urgent.[1] In
addition, Re has been widely used as the analogue of radioactive Tc to facilitate the
operation in ordinary laboratories[2, 3]. Thus, it is important to develop adsorbents of
Tc/Re considering environmentally and economically importance. Hierarchically
silica can avoid the disadvantages of macro pores and mesopores by virtue of the
special pore structures. And it has excellent chemical stability, thermal stability and
mechanical properties to withstand high acidity, high temperature, radioactivity and
other special environments. Therefore, hierarchically silica is a very good adsorption
substrate[4].
Herein, a novel adsorbent named as HPS-C-P was synthesized for removal of
ReO4- by two-step γ-ray radiation grafting 4-vinylbenzyl phosphonium chlorid onto
silanized hierarchilly silica, the synthesis route of HPS-C-P was shown in Figure 1. It
was found that the grafting yield positively correlated with monomer concentration
and absorbed dose. By controlling the reaction conditions two kinds of adsorbents
with the grafting yield of 0.251 and 0.782 mmolg-1 were synthesized, which was
named as HSP-C-P1 and HPS-C-P2, respectively. Both HPS-C-P1 and HPS-C-P2 had
fast adsorption kinetics for ReO4- (Figure 2). And their maximum adsorption
capacities were 46.9 and 140.5 mgg-1 calculated by modified Langmuir model,
respectively. The selectivity factor of HSP-C-P2 and HPS-C-P1 toward ReO4- relative
to NO3- were 159 and 64, respectively, which indicated good adsorption selectivity.
They also had good cycle performance, and can be desorbed by 1.9 M HNO3. XPS
and FTIR indicated the adsorption mechanism of HPS-C-P for ReO4- was ion
exchange.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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Figure 1 the synthetic route of HPS-C-P
Figure 2 Adsorption kinetics of ReO4- onto HPS-C-P
References
[1] Wang, Y.; Wang, C. Y., Recent advances of rhenium separation and enrichment in China:
Industrial processes and laboratory trials. Chinese Chemical Letters, 2018, 29(3), 345-352.
[2] Mei, L.; Li, F. Z.; Lan, J. H.; Wang, C. Z.; Xu, C.; Deng, H.; Wu, Q. Y.; Hu, K. Q.; Wang, L.; Chai,
Z. F.; Chen, J.; Gibson, J. K.; Shi, W. Q., Anion-adaptive crystalline cationic material for 99TcO4-
trapping. Nature Communications, 2019, 10.
[3] Han, D.; Li, X. X.; Cui, Y.; Yang, X.; Chen, X. B.; Xu, L.; Peng, J.; Li, J. Q.; Zhai, M. L.,
Polymeric ionic liquid gels composed of hydrophilic and hydrophobic units for high adsorption
selectivity of perrhenate. Rsc Advances, 2018, 8(17), 9311-9319.
[4] Li, X. X.; Hang, D.; Guo, T. T.; Peng, J.; Xu, L.; Zhai, M. L., Quaternary Phosphonium Modified Hierarchically Macro/Mesoporous Silica for Fast Removal of Perrhenate. Industrial &
Engineering Chemistry Research, 2018, 57(40), 13511-13518.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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P 3-6
Zein-based composite film with pH-sensitivity for drug controlling
release
Junhui Guo, Yufeng He*, Jianfeng Wang, Rongmin Wang§§§§§§§§§§§§§§
(Key Laboratory of Eco-Environment-Related Polymer Materials of Ministry of Education,
Institute of Polymer, College of Chemistry and Chemical Engineering, Northwest Normal
University, Lanzhou 730070, China.)
*E-mail: [email protected]
Films can be directly applied to the surface of the skin wound or mouth ulcer that
make drug and lesion can directly contact and improve the utilization rate of drug[1].
Commonly, synthetic polymers and natural polymers are used to prepare film-forming
materials. Furthermore, natural polymers have some advantages of biodegradability,
biocompatibility, renewability, safety and reliability. Zein, as a typical natural
polymers, has been paid to attention[2].
Here, using zein and nano-SiO2 as raw materials, the zein-based composite film
was prepared. Its morphology and structure were characterized by FT-IR, SEM and
TG. It was found that the obtained organic-inorganic hybrid polymer membrane was
uniform and transparent, and SiO2 was uniformly dispersed in the membrane which
improved its mechanical properties. By loading the vitamin B2 into the zein-based
composite film, its release behaviors were investigated. It was found that the release
rate got to 95% at neutral medium (pH: 7.4), which is much higher than that of in
weak acidic environments (pH: 5.8). The drug-loaded film was pH sensitive because
of addition of SiO2. That means the obtained zein-based composite film can be used
as a carrier for treating skin wounds or mouth ulcers.
Keywords: Natural polymers, Zein, pH-sensitive, Drug release
References:
[1] Li FY.; Wang RM.; He YF.; Li XX.; Song PF.; Yin XC.; Mao CW, Journal of
Controlled Release, 2011, 152,e92.
[2] Lv SY.; Liu J.; Pei F.; He YF.; Wang RM, Letters in Drug Design & Discovery,
2016, 13, 1099.
This research was supported by the National Natural Science Foundation of China (Grant No.
21364012, 21865030).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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P 3-7
Zein-based magnetic polymer aerogel as oil absorbing agent
Fawei Wang, Jianfeng Wang, Yufeng He, Rongmin Wang***************
(Key Laboratory of Eco-Environment-Related Polymer Materials of Ministry of Education,
Institute of Polymer, College of Chemistry and Chemical Engineering, Northwest Normal
University, Lanzhou 730070, China.)
*E-mail: [email protected]
Oil pollution is an important category of environmental pollution. Therefore, the
disposal of oily wastewater has become a worldwide challenge, and several
approaches have been proposed and employed to extract oil from water or realize
oil/water separation [1]. At present, oil-absorbing materials are mainly composed of
synthetic polymers, which is difficult to degrade to cause secondary pollution. As an
inexpensive natural polymer, zein is an amino acid-based vegetable protein with
biocompatibility and biodegradability. We found that zein can be used to prepare
edible composites and controlled release materials [2]. Herein, using sol-gel method
and freeze-drying technique, the zein-based polymer aerogel was prepared by zein
and poly (vinyl alcohol) (PVA). With further surface modification by silane coupling
agent and in-situ precipitation for introducing Fe3O4, the zein-based magnetic
polymer aerogel was successively prepared. Its morphology and structure were
characterized by FT-IR, SEM and TG. It indicated that the polymer aerogel had a
multi-layered network structure and the contact angle was 132.8o. The modified
aerogel have significant capabilities of oil-water separation, which will provide
efficient and sustainable options for water treatment and environmental protection.
Keywords: Natural polymers, Zein, Aerogel, Oil absorbing materials
References:
[1] Ma Q.; Yu Y.; Sindoro M.; Fane, A. G.; Wang R.; Zhang H, [J]. Adv. Mater. 2017,
29 (13): 1605361.
[2] Lv S.; Liu J.; Pei F.; He Y.; Wang R-M, [J]. Letters in Drug Design & Discovery.
2016, 13(10): 1099.
This research was supported by the National Natural Science Foundation of China (Grant No.
21364012, 21865030).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
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P 3-8
Microstructure and mechanical properties of aerogels prepared by
Freeze casting
Wang Liao
School of Science, Xihua University, Chengdu 610039 China
Abstract Aerogels are known as the lightest solids, and have the applicable
mechanical properties and various functions. In recent years, the family members of
aerogels and their applications expand rapidly. One reason for that is the preparation
process of freeze casting (FC) is simple and green. Inorganic aerogels, metal aerogels,
polymer aerogels and composite aerogels with different properties, such as thermal
insulation materials, sensors, electromagnetic interference shielding, absorbent,
separation, life science, supercapacitors, catalysis, etc. have been produced by this
method. Despite of this, the definition and influence factors of FC have not been
carefully analyzed in the literature, which becomes a bottleneck for novel aerogels
through this way. In this work, three different types of FC are distinguished and the
factors that affect the microstructure and physical properties are discussed.
Key words: aerogel; freeze casting; microstructure; mechanical properties
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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P 3-9
Controlled preparation of Nitrogen-doped carbon cryogels with
excellent carbon dioxide adsorption performance
Ze Liang Li1, Wei Gang Zhao1*
(College of Material Engineering, Fujian Agriculture and Forestry University, Fuzhou 350002,
PR China)
*E-mail: [email protected]
A series of cost effective nitrogen-doped carbon cryogels with excellent carbon
dioxide (CO2) adsorption performance were prepared from phenol, melamine and
formaldehyde (PMF) by sol-gel method, freeze-drying and carbonization. The
morphology, pore structure and chemical characteristics were investigated by
scanning electron microscopy (SEM), N2 adsorption-desorption at 77 K, X-ray
diffraction (XRD), X-ray photoelectron spectrometry (XPS) and Fourier transform
infrared spectroscopy (FTIR). The results show that the carbon cryogel is a kind of
porous material composed of nanoparticles stacked together, which has high specific
surface area (1406m2/g), high porosity and micropore capacity. Moreover, nitrogen
elements are firmly bound in the framework of carbon cryogel, and its nitrogen
content ranges 1.0%~2.1%. CO2 adsorption performance of carbon cryogel was tested,
and the results showed that the CO2 adsorption capacity was as high as 5.75mmol/g
(0℃, 1bar) and 4.78mmol/g (25℃, 1bar), which was higher than that of similar
materials, and the carbon cryogel had good CO2/N2 adsorption selectivity. And its
CO2 adsorption capacity and selectivity were correlated with the pore structure and
nitrogen doping of the carbon cryogels.
Keywords: Phenol melamine formaldehyde, Pore structure, Freeze-drying, CO2
capture
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
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P 4-1
Ionically Cross-Linked Silk Microfibers/Alginate Tough Composite
Hydrogels with Hierarchical Structures
Lei Meng, Changyou Shao, Jun Yang
(Beijing Key Laboratory of Lignocellulosic Chemistry, Beijing Forestry University, Beijing
100083, China.)
*E-mail: [email protected]
Developing hydrogels with enhanced mechanical properties have attracted broad
attention in recent years. In this work, we propose a facile procedure to prepare tough
composite hydrogels by incorporating silk microfibers (mSF) into alginate ionically
cross-linked network. The mSF gives rise to ionic bonds with Ca2+ and interfacial
hydrogen bonds because of the carboxyl groups on the surface of mSF, and the
neighboring alginate chains are interlinked by mSF, which synergistically lead to
efficient energy dissipation and prevention of stress concentration. The attained
composite hydrogels show superior elastic modulus (1.58 MPa), tensile strength (1.60
MPa) and unique adaptive interface response. Moreover, the mechanical properties of
the composite hydrogels can be tailored by the concentration of mSF and
post-crosslinking time by immersing the composite hydrogels in CaCl2 solution.
Intriguingly, the mechanical properties can be further improved through prestretching
methodology to align the alginate chains along the stress direction, where the oriented
hierarchical structures are formed and well-retained in the prestretched composite
hydrogels. We envisage that this study provides a general strategy for designing
composite hydrogels with both excellent and tunable mechanical properties, which
enriches the route of alginate hydrogels for promising applications where
high-loading requirement needed.
Keywords: Hydrogels, Alginate, Silk Fibroin, Reinforcement, Hierarchical Structures
References:
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
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Structure-Property Relationship. Biomacromolecules 2018, 19, 906-917. DOI:
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N. R. Tough Photocrosslinked Silk Fibroin/Graphene Oxide Nanocomposite
Hydrogels. Langmuir 2018, 34, 9238-9251. DOI: 10.1021/acs.langmuir.8b01141.
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2009, 30, 2826-2836. DOI: 10.1016/j.biomaterials.2009.01.040.
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Biocompatible Silk Fibroin/Cellulose Nanocomposite Films with High Mechanical
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[31] Zhu, Z.; Ling, S.; Yeo, J.; Zhao, S.; Tozzi, L.; Buehler, M. J.; Omenetto, F.; Li,
C.; Kaplan, D. L. High‐Strength, Durable All‐Silk Fibroin Hydrogels with Versatile
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[36] Wegst, U. G.; Bai, H.; Saiz, E.; Tomsia, A. P.; Ritchie, R. O. Bioinspired
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The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
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Single-Walled Carbon Nanotubes for Polysaccharide Hydrogels. ACS Appl. Mater.
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The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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P 4-2
Effects of zein on the formation of konjac glucomannan electrospun
nanofibres for controlled release of curcumin
Lin Wanga, Ruojun Mua, Yu Dua, Yuanzhao Lia, Chunhua Wua*, Jie Panga*
a College of food science, Fujian Agriculture and Forestry University, Fuzhou,
China, 350002
Abstract: The exploration of methods to produce biodegradable and bioactive
nanofibril films is of great scientific and technological interests. We reported a
strategy for constructiing of nanofibril films by using KGM and zein via
electrospinning technology. The characterization of the nanofibrial films was
conducted via Scanning electron microscopy (SEM), Thermogravimetric analysis
(TGA), Fourier transform infrared spectroscopy (FT-IR), X-ray photoelectron
spectroscopy (XPS), X-ray diffraction (XRD) and water contact angle measurements.
The interactions of hydrogen bonds between KGM and zein was confirmed, and the
addition of zein caused an enhancement of thermal properties and hydrophobicity.
The morphology and size of nanofibers significantly depended on zein contents. We
further loaded curcumin (Cur), a natural polyphenolic compound, within the
KGM/zein nanofibril films to investigate the antibacterial and antioxidating properties
for the novel nanofibril films, and the encapsulation efficiency was close to 95±2.2 %.
In comparison with a pure KGM and zein film, KGM/zein nanofibril films indicated
an excellent antibacterial activity against food-borne pathogens. Our work suggested
that the KGM/zein nanofibril films had a potential application in food packaging,
which opens a facile pathway to the modification of KGM-based biopolymer to form
nanofilms.
Keywords: Konjac glucomannan/zein; Curcumin; Nanofibril film;
Antibacterial/antioxidative properties
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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P 4-3
Zein-based composite film with pH-sensitivity for drug controlling
release
Junhui Guo, Yufeng He*, Jianfeng Wang, Rongmin Wang†††††††††††††††
(Key Laboratory of Eco-Environment-Related Polymer Materials of Ministry of Education,
Institute of Polymer, College of Chemistry and Chemical Engineering, Northwest Normal
University, Lanzhou 730070, China.)
*E-mail: [email protected]
Films can be directly applied to the surface of the skin wound or mouth ulcer that
make drug and lesion can directly contact and improve the utilization rate of drug[1].
Commonly, synthetic polymers and natural polymers are used to prepare film-forming
materials. Furthermore, natural polymers have some advantages of biodegradability,
biocompatibility, renewability, safety and reliability. Zein, as a typical natural
polymers, has been paid to attention[2].
Here, using zein and nano-SiO2 as raw materials, the zein-based composite film
was prepared. Its morphology and structure were characterized by FT-IR, SEM and
TG. It was found that the obtained organic-inorganic hybrid polymer membrane was
uniform and transparent, and SiO2 was uniformly dispersed in the membrane which
improved its mechanical properties. By loading the vitamin B2 into the zein-based
composite film, its release behaviors were investigated. It was found that the release
rate got to 95% at neutral medium (pH: 7.4), which is much higher than that of in
weak acidic environments (pH: 5.8). The drug-loaded film was pH sensitive because
of addition of SiO2. That means the obtained zein-based composite film can be used
as a carrier for treating skin wounds or mouth ulcers.
Keywords: Natural polymers, Zein, pH-sensitive, Drug release
References:
[1] Li FY.; Wang RM.; He YF.; Li XX.; Song PF.; Yin XC.; Mao CW, Journal of
Controlled Release, 2011, 152,e92.
[2] Lv SY.; Liu J.; Pei F.; He YF.; Wang RM, Letters in Drug Design & Discovery,
2016, 13, 1099.
This research was supported by the National Natural Science Foundation of China (Grant No.
21364012, 21865030).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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P 4-4
Synthesis of self-supporting composite nanowires based on
3D-network metallogel template
Botian Li, Da Xiao, Xue Zhou, Wei Shao,
Inorganic-polymer composite nanowires have triggered enormous interest
because of their unique properties and wide potential applications such as catalysis,
chemo-sensors, biomaterials, etc. In the past decades many researches have reported
the template synthesis of composite nanowires using anodized aluminum oxide,
porous polymer film or cylindrical polymer brushes, however, the resulted composite
nanowires in dispersion or powder exhibited the intrinsical disadvantages in
mechanical strength and processability, and that limited their further application. In
this work, we advocated a new strategy to produce the composite nanowires with
prominent stability and strength, for these nanowires could intertwine with each other,
builting a self-supporting network. Coordinated metallogels constituted of three
dimensional networks, including Ag(I) gel, Fe(III) gel and In(III) gel, were employed
as templates. These gels were all thermo-stable and easy to decompose after the
addition of competing ligands. Generally, a metallogel was prepared first, and then the
polymerization was in situ carried out using gel fibers as templates to produce
composite nanowires. The resulted nanowires were characterized by TEM and SEM,
wherein the polymer was coated on the outer layer, and gel fiber located in the inner
core. This morphology was formed by the template effect since the polymer/oligomer
in the solution was inclined to deposite on the nanofibers through van der Waals
forces. The product nanowires exhibited gel-like status as metallogel template, but
showed the enhanced mechnical strength. The inner metallogel template could be
directly removed by addition of ammonia to generate self-supporting nanotubes, also
it could be further employed as the precursor to produce self-supporting composite
nanowires with inorganic nanoparticles by post-treatment. Therefore, this versatile
and facile method may have applications in fabrication of various self-supporting
composite nanowires.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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P 5-1
Freeze and Heat-Resistant, Nonflammable and Highly Robust Ionic
Liquid-Based Click-Ionogels
Yongyuan Ren, Jiangna Guo, Ziyang Liu, Zhe Sun, Yiqing Wu, Lili Liu, Feng Yan*
(Department of Polymer Science and Engineering, College of Chemistry, Chemical Engineering
and Materials Science, Soochow University, Suzhou, 215123, China)
*E-mail: [email protected]
Gels that are freeze-resistant and heat-resistant having high ultimate tensile
strength are desirable in practical applications owing to their potential in designing
flexible energy-storage devices, actuators, and sensors. Here, a simple method for
fabricating ionic liquid (IL)-based click-ionogels using thiol-ene click chemistry
under mild condition is reported. These click-ionogels continue to exhibit excellent
mechanical properties and resilience, after ten thousand fatigue cycles. Moreover, due
to several unique properties of ILs, these click-ionogels exhibit high ionic
conductivity, transparency, and nonflammability performance over a wide
temperature range (-75 ℃ to 340 ℃). Remarkably, due to the outstanding properties
of the click ionogels, TENG using the gels as electrodes also displayed superior
mechanical stability and a wide operating temperature range. In combination with the
properties above, the click ionogels likely have promising applications for use in
extreme conditions in various electrical devices, such as flexible sensors, energy
storage devices, electronic skins, and wearable devices.
Keywords: Ionic liquids, Ionogels, Robust, Freeze/heat-resistant
References:
[1]. Ren YY.; Guo JN,; Liu ZY,; Sun S,; Wu YQ,; Liu LL,; Yan Y* (under
revision).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
163
P 5-2
Molecular dynamics simulation of rupture mechanism in nanofiller
filled polymer nanocomposites
Yangyang Gaoa, Liqun Zhanga*
a Center of Advanced Elastomer Materials. Beijing University of Chemical
Technology, Beijing, China.
Through coarse-grained molecular dynamics simulation, we aim to uncover the
rupture mechanism of the nanofiller filled polymer nanocomposites by characterizing
the structural and dynamic changes during the tension process. We find that the strain
at failure is corresponding to the coalescence of single void into larger voids, namely
the change of the free volume. And the minimum of the Van der Walls (VDWL)
energy reflects the maximum mobility of polymer chains and the largest number of
voids of polymer nanocomposites. After the failure, the stress gradually decreases
with the strain, accompanied by the contract of the highly orientated polymer bundles.
The number of voids is quantified as a function of the strain, exhibiting a
non-monotonic behavior because of the coalescence of small voids into larger ones at
high strain. However, the number of voids is greatly reduced by a stronger interfacial
interaction. In particular, with weak interfacial interaction, the nucleation of voids
occurs in the interface, and in the polymer matrix in the strong case. We
systematically study the effects of the interfacial interaction, temperature, the length
and volume fraction of nanofillers, chain length, bulk cross-linking density, interfacial
chemical bonds and grafted chains on the rupture behavior, such as the stress at failure,
the tensile modulus and the rupture energy. The rupture resistance ability increases
with the increase of the interfacial interaction, rod length, and bulk cross-linking
density. With the interfacial interaction increasing, it induces the rupture transition
from mode A (no bundles) to B (bundles).The transition point of the stress at failure as
a function of the temperature roughly corresponds to the glass transition temperature.
At longer chain length, a non-zero stress plateau occurs. And excessive chemical
bonds between polymer and nanofillers are harmful to the rupture property. We find
that an optimal volume fraction of nanofillers exists for the stress-strain behavior,
which can be rationalized by the formation of the strongest polymer-nanorod network,
leading to the slowest mobility of nanofillers. In addition, the rupture property first
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
164
increases and then decreases with the increase of the grafting density, which can
explained by the contribution of matrix chains, grafted chains, and nanofillers to the
total stress.
Keywords: Molecular dynamics simulation, polymer nanorod filled
nanocomposites, rupture.
*Corresponding Author: [email protected]
References:
1 Yangyang Gao, Liqun Zhang*, et al., Phys. Chem. Chem. Phys., 2014, 16,
18483-18492.
2 Yangyang Gao, Liqun Zhang*, et al., Phys. Chem. Chem. Phys., 2014, 16,
16039-16048.
3 Yangyang Gao, Liqun Zhang*, et al., Journal of Polymer Science Part B:
Polymer Physics. 2017, 55, 1005-1016.
4 Yangyang Gao, Liqun Zhang*, et al., Computational Materials Science. 2018,
142, 192-199.
5 Yangyang Gao*, Liqun Zhang*, et al., Composites Science and Technology.
2018, 167, 404-410.
6 Yangyang Gao, Liqun Zhang*, et al., RSC Advances. 2018, 8, 27786-27795.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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P 5-3
Research and application of implantable blood detection device based
on shape memory polymer
Lanlan Liu, Bocheng Zhang, Zujun Peng, Ying Chen, Xue Feng‡‡‡‡‡‡‡‡‡‡‡‡‡‡‡
(Frontier Research Center, Institute of Flexible Electronics Technology of THU. Zhejiang,
No.906 Yatai Road, Jiaxing, Zhejiang, China)
*E-mail: [email protected]
The detection of blood in the aorta plays a guiding role in the prevention and
treatment of cardiovascular diseases. The detection of local blood in the diseased
vessels is a difficult subject in scientific research. This paper introduces a sensor for
local blood detection that can be combined with a cardiovascular stent. The sensor
uses shape memory polymer (SMP) as a flexible substrate. After the cardiovascular
stent enters the lesion site of human body, the device is deformed by external
conditions to complete the device deployment and fixation. The sensing unit endows
the interdigital electrode with unique stretching and bending characteristics through
the design of the serpentine wire. The detection sensitivity and detection limit of the
sensor can be adjusted by designing the number and length of the interdigital
electrode through electric field simulation. Finally, the blood detection device was
fabricated by 3D printing and several key blood parameters were tested, and the
accuracy of the device was evaluated.
Keywords: Implantable blood detection device, Shape memory polymer, 3D printing
References:
[1] Zhou C.; Hedayati MK.; Zhu XH.; Nielsen F.; Levy U.; Kristensen A*, ACS Sens.
2018, 3, 784.
[2] Wu JJ.; Huang LM.; Zhao Q.; Xie T*, Chinese J. Polym. Sci. 2018, 36, 563.
[3] Chen YH.; Lu SY.; Zhang SS.; Li Y.; Qu Z.; Chen Y.; Lu BW.; Wang XY.; Feng
X*, Sci. Adv. 2017, 3, e1701629.
This research was supported by the Natural Science Foundation of Zhejiang Province, China
(Grant No. Q19E030011).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
166
P 5-4
Stretchable resistance sensor based on liquid metal direct writing
method
Bocheng Zhang, Lanlan Liu, Ruitao Tang, Qifeng Du, Ying Chen, Xue
Feng§§§§§§§§§§§§§§§
(Frontier Research Center, Institute of Flexible Electronics Technology of THU. Zhejiang,
No.906 Yatai Road, Jiaxing, Zhejiang, China)
*E-mail: [email protected]
With the development of flexible electronic technology, the combination of
liquid metal and micro-channel technology has been applied to the preparation of
interconnected structures, micro-fluid components and soft electrodes. It is a core
issue that adjusting the mechanical properties of flexible substrates enhance the
reliability and stability of liquid metal devices. In this project, we combined liquid
metal with direct writing technology to produce a stretchable resistance sensor which
could use on the wearable devices. The force distribution of the whole device during
tension is analyzed by mechanical simulation. According to the analysis results, we
optimized the shape of the device and the flow channel of the liquid metal. The
injection of liquid metal is accomplished by combining laser direct writing with
micro-channel technology. We analyzed the resistance change of liquid metal and the
physical state of liquid metal during tension, and explained the phenomenon that
resistance changes differently when liquid metals are filled and hollow.
Keywords: Stretchable resistance sensor, Liquid metal, Direct writing
References:
[1] Wang JX.; Cai GF.; Li SH.; Gao D.; Xiong JQ.; Lee PS*, Adv. Mater. 2018, 30,
1706157.
[2] Zhou XY.; Zhang RC.; Li LJ.; Zhang LJ.; Liu BX.; Deng ZS.; Wang LJ.; Gui Li*,
Lab Chip. 2019, 19, 807.
[3] Yang YQ.; Sun N.; Wen Z*.; Cheng P.; Zheng HC.; Shao HY.; Xia YJ.; Chen C.;
Lan HW.; Xie XK.; Zhou CJ.; Zhong J.; Sun X*.; , Lee ST*, ACS Nano 2018, 12, 2,
2027.
This research was supported by the Natural Science Foundation of Zhejiang Province, China
(Grant No. Q19E030011).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
167
P 5-5
Ionoprinting controlled information storage of fluorescent hydrogel
for hierarchical and multidimensional decryption
Xiao Xia Le1, Jia Wei Zhang1*, Tao Chen1*
(1Ningbo Institute of Material Technology and Engineering, Chinese Academy of Sciences,
Ningbo 315201, China)
*E-mail: [email protected]; [email protected]
Information storage and corresponding encryption/decryption are highly
important owing to the prevalence of counterfeit activities and information leakage in
the current age. Herein, we propose a novel method to store information via
controllable ionoprinting onto fluorescent hydrogel for hierarchical and
multi-dimensional decryption. Through incorporating pyrene moieties and carboxylic
groups into polymeric hydrogel network, fluorescence changing and controllable
shape deformation behaviors could be achieved and integrated by ionoprinting of Fe3+
ions. The diffusion of Fe3+ ions into fluorescent hydrogel can quench the fluorescence
of pyrene moieties, and chelate with carboxylic groups to generate anisotropic
structures for shape deformation simultaneously. Thus, fluorescence quenching-based
2D information and actuation-based 3D information could be hierarchically decrypted
when exposed to UV light and being put into water, respectively. Importantly, the
stored information could be erased by replacing Fe3+ with H+, which allows the
fluorescent hydrogel as a recyclable information storage material. This work may
provide new insights in designing and fabricating novel soft devices for hierarchical
and multidimensional information encryption, against the rising problems of
counterfeiting and confidential information disclosure.
Keywords: Information storage, Information decryption, Hydrogel actuator,
Fluorescence quenching, Anisotropic structures
References:
[1]. Le XX; Lu W; He J; Serpe MJ; Zhang JW*, Chen T*, Sci. China Mater. 2019,
62(6):831-839.
[2]. Le XX; Lu W; Zhang JW*; Chen T*, Adv. Sci. 2019, 6, 1801584.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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P 5-6
Multifunctional Wearable Sensors based on Repairable and
Recyclable Carbon Nanotubes Conductive Hydrogel
Haifei Wang, Jiameng Lu, Huayi Huang, Zhengchun Peng*
(Center for Stretchable Electronics and Nano Sensors, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education, College
of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, P. R. China)
*E-mail: [email protected]; [email protected]
Wearable electronic devices present booming development because of their
promising applications in fields including health monitoring, human-machine
interaction, consumer electronics and portable energy storage.[1] Conductive
hydrogels are a promising flexible electronic material due to its excellent mechanical
properties, high conductivity and good biocompatible.[2] However, inevitable
performance decaying of wearable devices is caused by dynamic deformation and
mechanical fatigue. We introduce novel repairable and recyclable conductive
hydrogels, which are prepared by covalent crosslinking poly(vinyl alcohol) (PVA)
and carbon nanotubes based on aldol reaction. The conductive hydrogels showed high
elastic property, good mechanical stability and excellent conductivity. By integrating
conductive hydrogel in wearable electronic devices, the wearable devices can be
repaired and fully recycled. We demonstrate high performance and multifunctional
wearable devices with capabilities on detection of finger gestures, radial artery and
electromyographic signal. As a candidate of flexible conductive materials, repairable
and recyclable conductive hydrogel show great potential on wearable devices and will
help to improve device stability and lifetime.
Keywords: Conductive hydrogel, Wearable sensor, Flexible electronic
References:
[1]. Zhang, Y.-Z.; Lee, K. H.; Anjum, D. H.; Sougrat, R.; Jiang, Q.; Kim, H.;
Alshareef, H. N.*, Sci. Adv. 2018, 4 (6), eaat0098.
[2]. Yuk, H.; Lu, B.; Zhao, X.*, Chem. Soc. Rev. 2019,48(6), 1642-1667.
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
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P 5-7
Autonomous swarming of biomolecular robots utilizing the
sequential signaling of DNA
Jakia Jannat Keya1, Arif Md. Rashedul Kabir1, Akinori Kuzuya2 and Akira Kakugo1,3
(1 Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan ;2 Department of
Chemistry and Materials Engineering, Kansai University, Osaka 564-8680, Japan; 3Graduate
School of Chemical Sciences and Engineering, Hokkaido University, Sapporo 060-0810, Japan)
*E-mail: [email protected]
Nature constructs complex structures by self-assembly process to display
emergent functions. Swarming is a fascinating example of self-assembly of living
organisms into large scale structures offering several advantages. Although realizing
such behavior as the nature does always inspire scientists, mimicking such features
remained the biggest challenge. Recently we have demonstrated swarming of
molecular sized self-propelled objects such as natural biomolecular system
microtubule (MT)/kinesin powered by adenosine tri-phosphate (ATP) to construct
molecular swarm robots. DNA crosslinker complementary to the receptors can pair up
DNA tethered MTs to form swarms with both translational and rotational motion1,2.
However, to construct swarm robot, autonomous information transfer by the robots is
one of the essential criteria. Controlling the swarming of MTs by sequential DNA
input signal can further enhance the autonomous behavior of the robots. Such
information transfer exploration by MT swarm robots could offer applications in
diagnosis of analytes like miRNA and so on.
Keywords: Swarming, biomolecular system, DNA, swarm robot, autonomous
information transfer.
References:
[1]. Keya JJ.; Suzuki R.; Kabir AMR.; Inoue D.; Asanuma H.; Kazuki S.; Hess H.;
Kuzuya A.,* Kakugo A* Nat. Commun. 2018, 9:453
[2]. Keya JJ.; Kabir AMR.; Inoue D.; Kazuki S.; Hess H.; Kuzuya A.,* Kakugo A*
Sci. Rep. 2018, 8:11756
This work was supported by the National Natural Science Foundation of China (31300488).
The 3rd International Symposium for Advanced Gel Materials & Soft Matters (ISAGMSM),
Shaanxi University of Science and Technology, Xian, Shaanx Province, China.
June 14-17, 2019
170
P 5-8
Super-elastic and multifunctional polymer hydrogel strengthened by
low-content cement-released nanoparticles
Guo Xing Sun1,2*, Rui Liang1, Xiao Sai Hu1, Xiao Xu Liang1, Hong Yao Ding1
(1 Joint Key Laboratory of the Ministry of Education, Institute of Applied Physics and Materials
Engineering, University of Macau, Avenida da Universidade, Taipa, Macau SAR, China. 2 Department of Physics and Chemistry, Faculty of Science and Technology, University of Macau,
Avenida da Universidade, Taipa, Macau SAR, China.)
*E-mail: [email protected]
Portland cements are innovatively used to obtain sub-5 nm particles. Such novel
cement-released nanoparticles pioneer super-elastic and multifunctional polymer
hydrogel, and drying-resistance oil gel. The calcium hydroxide nano-spherulites (CNS)
with diameters < 5 nm release from the surface of cement particles when cement
particles are dispersed in water at 0℃. A very low content of CNS can remarkably
strengthen and tough polymer hydrogels due to the small size effect of CNS. The
poly(acrylamide) (PAM)/ CNS hydrogel cross-linked by 40 ppm CNS can be
stretched to more than 100-times strain with a stress of more than 500 KPa. The poly
(acrylic acid) (PAA)/CNS super-adsorbent hydrogel enhanced by 200 ppm CNS
shows excellent adsorption capacity for the removal of methylene blue dye (2,100
mg/g). Furthermore, conductive polymer/CNS hydrogel possesses high electrical
conductivity (20,830 S/m) and can be stretched up to 1,076% strain, showing
potential application in flexible stretchable electronic devices.
Keywords: Gel, Calcium hydroxide nano-spherulites, Super-elastic, Multifunctional
References:
[1]. Sun GX.; Li ZJ*; Liang R.; Weng LT.; Zhang LN, Nat. Commun. 2016, 7, 12095.
[2]. Hu XS.; Liang, R.; Sun GX*, J Mater Chem A. 2018, 36, 17612.
This research was supported by Science and Technology Development Fund from Macau
(FDCT-078/2017/A2).