Levoflox (Levofloxacin Tablets)

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Levoflox (Levofloxacin Tablets)

Levofloxacin Tablets

Clearsky Pharmacy

Levoflox (Levofloxacin Tablets) is a fluoroquinolone antibiotic that fights bacteria in the body.Levoflox tablets are used to treat bacterial infections of the skin, sinuses, kidneys, bladder, or prostate. Levofloxacin tablets are also used to treat bacterial infections that cause bronchitis or pneumonia, and to treat people who have been exposed to anthrax. Levofloxacin tablets should be used only for infections that cannot be treated with a safer antibiotic.

Levoflox Tablets

Clearsky Pharmacy

Levoflox Tablets are manufactured by Cipla Ltd. (Website: www.cipla.com)

Levofloxacin Tablets Brand Names

Clearsky Pharmacy

Levofloxacin tablets are available as Levaquin, Tavanic, Levoflox, Glevo, Leon, Levomac, Lovifox and Milivo .

Active Ingredient

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The active ingredient contained in Levoflox is Levofloxacin. Each Levoflox tablet contains Levofloxacin Hemihydrate, IP, equivalent to 250 mg, 500 mg or 750 mg of Levofloxacin.

Chemical Structure

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The structure of Levofloxacin is given below:

Uses of Levoflox Tablets

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Levoflox tablets are used for the treatment of the following infections due to Levofloxacin susceptible microorganisms: Acute sinusitis, acute exacerbation of chronic bronchitis, community-acquired pneumonia, complicated urinary tract infections including pyelonephritis, skin and soft tissue infections and prostatitis.

Levofloxacin Dosage

Clearsky Pharmacy

Nosocomial Pneumonia: 750 mg every 24 hours for a duration of 7 to 14 days

Community Acquired Pneumonia : 750 mg every 24 hours for a duration of 5 days or 500 mg for a duration of 7 to 14 days

Acute Bacterial Sinusitis: 500 mg every 24 hours for a duration of 10 to 14 days

Acute Bacterial Exacerbation of Chronic Bronchitis: 500 mg every 24 hours for a duration of 7 days

The dosage of Levoflox tablets (Levofloxacin) is given below:

Levoflox Dosage

Clearsky Pharmacy

Complicated Skin and Skin Structure Infections (SSSI): 750 mg every 24 hours for a duration of 7 to 14 days.

Uncomplicated SSSI: 500 mg every 24 hours for a duration of 7 to 10 days.

Chronic Bacterial Prostatitis: 500 mg every 24 hours for a duration of 28 days.

Complicated Urinary Tract Infection or Acute Pyelonephritis: 250 mg every 24 hours for a duration of 10 days.

Uncomplicated Urinary Tract Infection: 250 mg every 24 hours for a duration of 3 days.

The dosage of Levoflox tablets (Levofloxacin) is given below:

Levoflox Dosage

Clearsky Pharmacy

Inhalational Anthrax (Post-Exposure): The dosage for Adults and Pediatric Patients more than 50 kg and 6 months of age or more is 500 mg every 24 hours for 60 days. In case of Pediatric Patients 6 months of age or more and weighing less than 50 kg the dosage is 8 mg/kg twice a day subject to the condition that the dose must not exceed 250 mg per dose for 60 days.

The dosage of Levoflox tablets (Levofloxacin) is given below:

Storage Instructions

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Levoflox (Levofloxacin Tablets) have to be stored at controlled room temperature i.e. from 20C to 25C (68F to 77F) with excursions permitted between 15 to 30C (59 to 86F). Protect from light and moisture.Keep this as well as all other medicines away from children and pets.

Warnings

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Fluoroquinolones, including Levofloxacin Tablets (Levoflox), are associated with an increased risk of tendinitis and tendon rupture in all ages. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. This medicine may exacerbate muscle weakness in persons with myasthenia gravis.Anaphylactic reactions and allergic skin reactions, serious, occasionally fatal, can occur after first dose.Hematologic (including agranulocytosis, thrombocytopenia), and renal toxicities can occur after multiple doses. Some cases of severe, and sometimes fatal, hepatoxicity has also been reported.Central nervous system effects, including convulsions, anxiety, confusion, depression, and insomnia can occur after the first dose.

Levoflox Tablets

Clearsky Pharmacy

Contraindications

Levoflox is contraindicated in patients with a hypersensitivity to Levofloxacin or any other component of this medication. This medicine is also contraindicated in patients with epilepsy, in patients with a history of tendon disorders related to fluoroquinolones administration..Also contraindicated in children or growing adolescents, during pregnancy and in breastfeeding women.

Levoflox Side Effects

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The most common Levoflox side effects occurring in 3% or more of the patients undergoing treatment with this medicine are nausea, headache, diarrhea, insomnia, constipation and dizziness.

Levoflox Overdose

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In the case of an acute Levoflox overdosage, the stomach should be emptied. The patient should be observed and appropriate hydration maintained. Levofloxacin is not efficiently removed by haemodialysis or peritoneal dialysis. Levofloxacin tablets exhibit a low potential for acute toxicity.

Levofloxacin During Pregnancy

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Levoflox (Levofloxacin Tablets) has been classified by the US FDA as Pregnancy Category C. Levofloxacin was not teratogenic in rats at oral doses as high as 9.4 times the highest recommended human dose based upon relative body surface area. There are, however, no adequate and well-controlled studies in pregnant women. This medicine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Levoflox Tablets

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Clearsky Pharmacy

Levoflox (Levofloxacin Tablets) by Cipla Limited, India.