MILD COGNITIVE IMPAIRMENT & DEMENTIA MRI PROTOCOL

• High Resolution axial DP-T2 TSE• 1.2 mm isotropic sagittal T1 3D MP-RAGE

(centered on thalamus)

• Coronal FLAIR• Axial T2 Gradient Echo• Diffusion Tensor Image (DTI)

Note: 1.- If necessary T1 3D MP-RAGE can be used for Voxel Based Morphometry2.- Axial T2 GE to discover small blood foci secondary to amyloid angiopathy

• Entorhinal cortex• Hippocampus• Medial Orbital gyrus• Cingulum

– Subgenual– Retrosplenial

Mild Cognitive Impairment. Strategic Areas Study

Diffusion Tensor Image VOIs.-

Entorhinal cortex

DTI VOIs.Medial Orbital Gyrus

Retrosplenial

Cingulum

Subgenual Cingulum

Hippocampus