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  • 1. NEMOCO srl Neuromotor Controlling OperatorsDOCUMENTAZIONE SCIENTIFICA DEL CROSYSTEM Il CroSystem uno strumento ed un metodo integrati in grado di indurre modifiche plastiche nel Sistema nervoso Centrale (Marconi B et al. 2008) e migliorare la performance motoria mediante lapplicazione di una leggera vibrazione meccanica localmente applicata su singoli muscoli.Gli effetti si instaurano rapidamente (Marconi B et al. 2008; Brunetti O et al. 2006; Filippi GM et al. 2009) e sono lungamente peristenti (Fattorini L et al. 2006; Brunetti O et al. 2006; Marconi B et al. 2008; Filippi GM et al. 2009). Gli effetti consistono in: 1. aumento della resistenza alla fatica (Fattorini L et al. 2006) 2. diminuzione del tempo di esplosione della forza (Fattorini L et al. 2006)3. aumento della forza e della potenza (Fattorini L et al. 2006; Brunetti O et al. 2006; Filippi GM et al. 2009) 4. aumento dellaltezza nel balzo (Filippi GM et al. 2009)5. aumento della stabilit nella postura (Brunetti O et al. 2006; Filippi GM et al. 2009)6. diminuzione della spasticit e recupero di funzione motoria (Marconi B, et al. 2008; Marconi B et al 2009).Tutti gli studi convergono sullipotesi che il meccanismo dazione consista in un miglioramento del processing propriocettivo e del controllo articolare attraverso un miglioramento del gioco agonisti-antagonisti (Fattorini L et al. 2006; Brunetti O et al. 2006; Filippi GM et al. 2009). Il maggior controllo dellimpedenza articolare giustifica la resistenza alla fatica, la migliore esplosivit, laumento di stabilit e la diminuzione della spasticit (Marconi B et al. 2008 E 2009). Le caratteristiche applicative per avere il massimo risultato con il minimo tempo di trattamento sono: 3 applicazioni al giorno di 10 minuti ognuna intervallate da 10-30 secondiVia F.Siacci 38 00197 Roma, P.IVA 06331541000 @mail: nemoco.informa@tiscali.it www.nemoco.it

2. NEMOCO srl Neuromotor Controlling Operators di pausa, per 3 giorni consecutivi, di una lieve vibrazione di 0,1-0,5 mm. Le applicazioni vanno eseguite sul gruppo muscolare da trattare. Poich 0,1-0,5 mm di vibrazione e corrispondenti a circa 0,002 mm alle fibre muscolari (Filippi GM et al. 2009) il procedimento del tutto innocuo e applicabile a qualsiasi et (da 2-3 anni a oltre 90). Nessuno studio, ad oggi, ha riportato effetti collaterali significativi. La lunga durata degli effetti, (mesi o permanenti, a fronte di 90 minuti applicativi rendono lo strumento facilmente applicabile su grandi numeri di pazienti. Campi applicativi: 1.Pazienti neurologici a. Ictus acuti, subacuti e cronici b. Traumatizzati cranici c. Sclerosi multiple d. Midollari e. Paralisi periferiche f. paralisi cerebrali infantili2.Pazienti ortopedici a. Esiti di traumi b. Esiti chirurgici c. Forme infiammatorie (artrite reumatoide, artriti) d. Forme artrosiche3.Terza et per vincere lastenia, la debolezza, prevenire le cadute. 4.SPORT per aumentare la forza esplosiva la resistenza, la stabilizzazione articolareRiabilitazione ortopedica, neurologica, della terza et e in generale in tutte le forme caratterizzate da sarcopenia o da ipovalidit funzionale. Particolarmente indicata linterazione con la riabilitazione tradizionale (Brunetti O et al. 2006;Filippi GM et al. 2009; Marconi B et al. 2009). Importante lazione sulla spasticit da lesioni centrali nel migliorare il tono e la coordinazione, aprendo nuove strade alla riabilitazione (Marconi B, et al. 2008b; Marconi B et al 2009). Via F.Siacci 38 00197 Roma, P.IVA 06331541000@mail: nemoco.informa@tiscali.it www.nemoco.it 3. NEMOCO srl Neuromotor Controlling Operators Principali riferimenti bibliografici 1. Brunetti O, Botti FM, Roscini M, Brunetti A, Panichi R, Filippi GM, Pettorossi VEEffects of quadriceps muscle vibration on leg power and knee joint laxity of femalevolleyball players submitted to Journal of Athletic Training 2010 2. Camerota F, Galli M, Celletti C, Vimercati S, Cimolin V, Tenore N, Filippi GM,Albertini G. Quantitative effects on gait pattern of repeated muscle vibrations: a 5-yr-old case study.submitted to Disorder and Disability 2010 3. Marconi B, Filippi GM, Koch G, Pecchioli C, Versace V, Camerota F, Saraceni VM,Caltagirone C. Long-term effects on cortical excitability and motor recovery inducedby repeated muscle vibration in chronic stroke patients. In stampa Neurorehabilitationand Neural Repair 2010 4. Filippi GM, Brunetti O, Botti FM, Panichi R, Roscini M, Camerota F, Cesari M,Pettorossi VE. Improvement of stance control and muscle performance induced byfocal muscle vibration in young-elderly women: a randomized controlled trial. ArchPhys Med Rehabil. 2009 Dec;90:2019-25 5. Marconi B, Filippi GM, Koch G, et al. Long-term effects on motor cortical excitabilityinduced by repeated muscle vibration during contraction in healthy subjects. J NeurolSci 2008b;275:51-9 6. Fattorini L, Ferraresi A, Rodio A, Azzena GB, Filippi GM. Motor performancechanges induced by muscle vibration. Eur J Appl Physiol 2006;98:79-87.7. Brunetti O, Filippi GM, Lorenzini M, Liti A, Panichi R, Roscini M, et al.Improvement of posture stability by vibratory stimulation following anterior cruciateligament reconstruction. Knee Surg Sports Traumatol Arthrosc 2006;14:11807.Via F.Siacci 38 00197 Roma, P.IVA 06331541000 @mail: nemoco.informa@tiscali.it www.nemoco.it 4. NEMOCO srlNeuromotor Controlling OperatorsVia F.Siacci 38 00197 Roma, P.IVA 06331541000 @mail: nemoco.informa@tiscali.it www.nemoco.it 5. NEMOCO srl Neuromotor Controlling Operators ABSTRACTS DEI PRINCIPALI LAVORIEFFECTS OF QUADRICEPS MUSCLE VIBRATION ON LEG POWER AND KNEE JOINT LAXITY OF FEMALE VOLLEYBALL PLAYERS (submitted to Journal of Athletic Training 2010) Orazio Brunetti PhD(*), Fabio M. Botti MD(*), Mauro Roscini HSG(*), Antonella Brunetti MD(), Roberto Panichi PhD(*), Guido Filippi MD(), Vito Enrico Pettorossi MD(+) (*) () Department of Internal Medicine, Section of Human Physiology, University of Perugia, Via del Giochetto, 06100 Perugia, Italy;() Department of Clinical Orthopedics and Traumatology, University of Perugia; Institute of Human Physiology - Catholic University - Rome (Italy) Abstract Context: High explosive power, reactive force and joint stability are required in volleyball players. Common training methods have a modest efficacy and when improperly applied, they may be associated with an increased risk of injury. Objective: To determine the effect of the mechanical vibration, applied focally and repeatedly (repeated muscle vibration = rMV) on the quadriceps muscles on explosive and reactive leg power and knee laxity of female women players (age 23 4 years). Design: A double-blind randomized controlled trial. Setting: Controlled laboratory environment. Patients or other partecipants: Eighteen healthy volleyball female athletes, belonging to the same team of senior regional level (age = 22.7 3 years, height = 1,803 5 m, mass = 64 4 Kg). Intervention(s): Participants were randomly assigned to 3 groups, each composed of 6 women: Vibration on Contracted quadriceps = VC; Vibration in Relaxed muscle = VR; placebo. rMV parameters were: 100Hz, 300500 m, in three 10-minute sessions a day for 3 consecutive days. Main Outcome Measure(s) : explosive leg power, reactive leg power, knee joint laxity. Via F.Siacci 38 00197 Roma, P.IVA 06331541000@mail: nemoco.informa@tiscali.it www.nemoco.it 6. NEMOCO srlNeuromotor Controlling Operators Results: In VC group explosive and reactive leg power increased by ~20% at 30 days and by 30% at 240 days after the intervention. Knee laxity also changed decreasing by 15% at 30 ~days and ~25% at 240 days. These values were significantly different compared to those of the other groups (P< .05), in which the increase in explosive and reactive leg powers and the decrease in knee joint laxity were ~5% at 30 days and ~10% at 240 days. Conclusions: rMV is a short-lasting and noninvasive protocol that can significantly and persistently improves muscle performance and knee laxity in volleyball women players.Via F.Siacci 38 00197 Roma, P.IVA 06331541000 @mail: nemoco.informa@tiscali.it www.nemoco.it 7. NEMOCO srl Neuromotor Controlling Operators QUANTITATIVE EFFECTS ON GAIT PATTERN OF REPEATED MUSCLE VIBRATIONS: A 5-YR-OLD CASE STUDY (submitted to Disorder and Disability 2010) Camerota F1, Manuela Galli2,3, Claudia Celletti1, Sara Vimercati2, Veronica Cimolin2, Nunzio Tenore3, Filippi GM4, Giorgio Albertini3 1 Physical Medicine and Rehabilitation Division, Umberto I Hospital, Sapienza University of Rome, 00185 Rome, Italy; 2 Bioeng. Dept. Politecnico di Milano, P.za Leonardo da Vinci 32, 20133 Milano, Italy; 3 IRCCS San Raffaele Pisana - Tosinvest Sanit, Via della Pisana4 235, Roma, Italy;Institute of Human Physiology, Catholic University of Rome, 00168 Rome, Italy Abstract In this case study we investigated quantitatively and objectively the effects of repeated muscle vibration (rMV) of triceps surae for the reduction of equinus foot deformity due to calf spasticity in a 5-yr-old patient with Cerebral Palsy. His gait pattern was evaluated before and one month after the treatment using Gait Analysis, in terms of distal and proximal joints kinematics. The obtained results demonstrated that rMV had positive effects on the patients gait pattern, in terms of spatio-temporal parameters (stance duration and step length) and of angles at all lower limb joints, not only at the joint directly involved by the treatment (i.e. ankle and knee joints) but also at proximal joints (i.e. pelvis and hip joint). These results showed that the rMV technique seems to be a reasonable option for the gait pattern improvement in CP, which can be used also in very young patient. Via F.Siacci 38 00197 Roma, P.IVA 06331541000@mail: nemoco.informa@tiscali.it www.nemoco.it 8. NEMOCO srlNeuromotor Controlling OperatorsVia F.Siacci 38 00197 Roma, P.IVA 06331541000 @mail: nemoco.informa@tiscali.it www.nemoco.it 9. NEMOCO srlNeuro