Biological Sequence Analysis Project Presentation - SNU · PDF fileBiological Sequence...

Preview:

Citation preview

  • Biological Sequence Analysis Biological Sequence Analysis Project PresentationProject Presentation

    Project2)

    Using HMMER to Search Homologues Protein Family

    2002-20631

  • Tutorial Execution to Understand HMMER

    Install Linux -> Not Complete

    Trial to Dos version Dowonload from HMMER Homepagehttp://hmmer.wustl.edu/

  • After downloads, creat folder at C:hmmer and file is unzipped.

    Get multiple sequence alignment of a protein domain(protein sequence family) from Pfam databaes

    http://pfam.wustl.edu/

    http://pfam.wustl.edu/http://pfam.wustl.edu/

  • My interesting protein family is Aminoacyl-tRNA Synthetase(ARS)

    What is Aminoacyl-tRNA Synthetase?

  • ARS domain search from Pfam database

  • HMM construction with hmmbuild

  • HMM calibration with hmmcalibrate

    Biological Sequence Analysis Project Presentation

Recommended