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๑ ทศวรรษ กบัการพฒันาวคัซีน และการสร้างเสริมภูมคิุ้มกนัโรค
ในประเทศไทยศุภมิตร ชุณหสุทธิวฒน
24 กรกฏาคม 2014
มุมมอง
1995 – 2004 2005 – 2014
National immunization program
Vaccine development & production
Policy coordination mechanisms
Para
llel t
imel
ines
Vaccine quality control & assurance
Disease and AEFI surveillance
1995 – 2004 2005 – 2014
National immunization program
Vaccine development & production
Policy coordination mechanisms
Para
llel t
imel
ines
1995 – 2004 2005 – 2014
National immunization program Pa
ralle
l tim
elin
es
1995 DTP-HB pilot in Chiangrai
1994 NID started for polio eradication
1997 last case of polio in Thailand 1997 MMR introduced countrywide
2000 JE introduced countrywide
2005 dT replaced TT 2008 DTP-HB all prov.
2008 Flu for risk pop.
1995 – 2004 2005 – 2014
National immunization program Pa
ralle
l tim
elin
es
1995 DTP-HB pilot in Chiangrai
1994 NID started for polio eradication
1997 last case of polio in Thailand 1997 MMR introduced countrywide
2000 JE introduced countrywide
2005 dT replaced TT 2008 DTP-HB all prov.
2008 Flu for risk pop.
BCG
DTP
OPV
HB
JE
TT / dT
DTP-HB
M
MMR
Influenza
Neonatal Tetanus
0
20
40
60
80
100
0
20
40
60
80
100
1977 1981 1985 1989 1993 1997 2001 2005 2009
1995 – 2004 2005 – 2014
National immunization program Pa
ralle
l tim
elin
es
1995 DTP-HB pilot in Chiangrai
1994 NID started for polio eradication
1997 last case of polio in Thailand 1997 MMR introduced countrywide
2000 JE introduced countrywide
2005 dT replaced TT 2008 DTP-HB all prov.
2008 Flu for risk pop.
BCG
DTP
OPV
HB
JE
TT / dT
DTP-HB
M
MMR
Influenza
Neonatal Tetanus
0
20
40
60
80
100
0
20
40
60
80
100
1977 1981 1985 1989 1993 1997 2001 2005 2009
1995 – 2004 2005 – 2014
National immunization program Pa
ralle
l tim
elin
es
1995 DTP-HB pilot in Chiangrai
1994 NID started for polio eradication
1997 last case of polio in Thailand 1997 MMR introduced countrywide
2000 JE introduced countrywide
2005 dT replaced TT 2008 DTP-HB all prov.
2008 Flu for risk pop.
2010 vaccine supply by NHSO . --------------------
2011 pilot on Rota started in Sukhothai . ---------
2014 pilot on HPV started in Ayuthaya . --
Rescheduling & campaigns to cope with re-emergences
1995 – 2004 2005 – 2014
National immunization program Pa
ralle
l tim
elin
es
1995 DTP-HB pilot in Chiangrai
1994 NID started for polio eradication
1997 last case of polio in Thailand 1997 MMR introduced countrywide
2000 JE introduced countrywide
2005 dT replaced TT 2008 DTP-HB all prov.
2008 Flu for risk pop.
2010 vaccine supply by NHSO . --------------------
2011 pilot on Rota started in Sukhothai . ---------
2014 pilot on HPV started in Ayuthaya . --
Rescheduling & campaigns to cope with re-emergences
1995 – 2004 2005 – 2014
Vaccine development & production
Para
llel t
imel
ines
Mahidol maintaining continuous dengue vac development
GPO shifted JEV from Nakayama to Beijing strain GPO attempted LAV-JE, aborted
GPO stopped DTP to improve GMP
GPO constructingFlu manufacture
NSTDA & TCELS supporting dengue vac
GPO’s LAIV H1N1 licensed, H5N2 in clinical trials
TRCS maintaining BCG production TRCS upgrading BCG production
Bionet-Asia established as first private sector developer & producer, making continuous progress
Deve
lopm
ent
Prod
uctio
n GPO-MBP supplying EPI
Attempts on TB, Chik, EV7
Historical phase III HIV trial
1995 – 2004 2005 – 2014
Vaccine development & production
Para
llel t
imel
ines
Mahidol maintaining continuous dengue vac development
GPO shifted JEV from Nakayama to Beijing strain GPO attempted LAV-JE, aborted
GPO stopped DTP to improve GMP
GPO constructingFlu manufacture
NSTDA & TCELS supporting dengue vac
GPO’s LAIV H1N1 licensed, H5N2 in clinical trials
TRCS maintaining BCG production TRCS upgrading BCG production
Bionet-Asia established as first private sector developer & producer, making continuous progress
Deve
lopm
ent
Prod
uctio
n GPO-MBP supplying EPI
Attempts on TB, Chik, EV7
Historical phase III HIV trial
Veterinary vaccine manufacture under DLD
National Bio-pharma Center
(NBF)
1995 – 2004 2005 – 2014
Policy coordination mechanisms
Para
llel t
imel
ines
1992 MOPH appointed committee on national vaccine capacity advised bidding for IVI in Thailand, setting up NVI as IVI counterpart
1995 – 2004 2005 – 2014
Policy coordination mechanisms
Para
llel t
imel
ines
1992 MOPH appointed committee on national vaccine capacity advised bidding for IVI in Thailand, setting up NVI as IVI counterpart
MOPH submitted a proposal to UNDP inviting IVI establishment in Thailand.
1995 – 2004 2005 – 2014
Policy coordination mechanisms
Para
llel t
imel
ines
1992 MOPH appointed committee on national vaccine capacity advised bidding for IVI in Thailand, setting up NVI as IVI counterpart
MOPH submitted a proposal to UNDP inviting IVI establishment in Thailand.
1995 – 2004 2005 – 2014
Policy coordination mechanisms
Para
llel t
imel
ines
1992 MOPH appointed committee on national vaccine capacity advised bidding for IVI in Thailand, setting up NVI as IVI counterpart
MOPH submitted a proposal to UNDP inviting IVI establishment in Thailand.
1995 – 2004 2005 – 2014
Policy coordination mechanisms
Para
llel t
imel
ines
1992 MOPH appointed committee on national vaccine capacity advised bidding for IVI in Thailand, setting up NVI as IVI counterpart
MOPH submitted a proposal to UNDP inviting IVI establishment in Thailand.
1990’s - meetings & workshops on national mechanism for vaccine policy and capacity
NVC appointed by Cabinet , NVC secretary office in DDC/MOPH
1995 – 2004 2005 – 2014
Policy coordination mechanisms
Para
llel t
imel
ines
1992 MOPH appointed committee on national vaccine capacity advised bidding for IVI in Thailand, setting up NVI as IVI counterpart
MOPH submitted a proposal to UNDP inviting IVI establishment in Thailand.
1990’s - meetings & workshops on national mechanism for vaccine policy and capacity
NVC appointed by Cabinet , NVC secretary office in DDC/MOPH
2005 Government approved national vaccine strategic plan proposed by NVC/MOPH
2011 - NVI in DDC
2012 - NVI as PSO
มุมมอง / ภาพรวม• Gaps in vaccine security• Past records of successes• Potential capacities in
multi-sector partners • Huge enthusiasms for
development and cooperation • Ongoing efforts• Challenges
• Policy coordination & support• Human resource development• Trust & team work • Regional competition &
cooperation
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