๑ ทศวรรษ กบัการพฒันาวคัซีน และการสร้างเสริมภูมคิุ้มกนัโรค

ในประเทศไทยศุภมิตร ชุณหสุทธิวฒน

24 กรกฏาคม 2014

มุมมอง

1995 – 2004 2005 – 2014

National immunization program

Vaccine development & production

Policy coordination mechanisms

Para

llel t

imel

ines

Vaccine quality control & assurance

Disease and AEFI surveillance

1995 – 2004 2005 – 2014

National immunization program

Vaccine development & production

Policy coordination mechanisms

Para

llel t

imel

ines

1995 – 2004 2005 – 2014

National immunization program Pa

ralle

l tim

elin

es

1995 DTP-HB pilot in Chiangrai

1994 NID started for polio eradication

1997 last case of polio in Thailand 1997 MMR introduced countrywide

2000 JE introduced countrywide

2005 dT replaced TT 2008 DTP-HB all prov.

2008 Flu for risk pop.

1995 – 2004 2005 – 2014

National immunization program Pa

ralle

l tim

elin

es

1995 DTP-HB pilot in Chiangrai

1994 NID started for polio eradication

1997 last case of polio in Thailand 1997 MMR introduced countrywide

2000 JE introduced countrywide

2005 dT replaced TT 2008 DTP-HB all prov.

2008 Flu for risk pop.

BCG

DTP

OPV

HB

JE

TT / dT

DTP-HB

M

MMR

Influenza

Neonatal Tetanus

0

20

40

60

80

100

0

20

40

60

80

100

1977 1981 1985 1989 1993 1997 2001 2005 2009

1995 – 2004 2005 – 2014

National immunization program Pa

ralle

l tim

elin

es

1995 DTP-HB pilot in Chiangrai

1994 NID started for polio eradication

1997 last case of polio in Thailand 1997 MMR introduced countrywide

2000 JE introduced countrywide

2005 dT replaced TT 2008 DTP-HB all prov.

2008 Flu for risk pop.

BCG

DTP

OPV

HB

JE

TT / dT

DTP-HB

M

MMR

Influenza

Neonatal Tetanus

0

20

40

60

80

100

0

20

40

60

80

100

1977 1981 1985 1989 1993 1997 2001 2005 2009

1995 – 2004 2005 – 2014

National immunization program Pa

ralle

l tim

elin

es

1995 DTP-HB pilot in Chiangrai

1994 NID started for polio eradication

1997 last case of polio in Thailand 1997 MMR introduced countrywide

2000 JE introduced countrywide

2005 dT replaced TT 2008 DTP-HB all prov.

2008 Flu for risk pop.

2010 vaccine supply by NHSO . --------------------

2011 pilot on Rota started in Sukhothai . ---------

2014 pilot on HPV started in Ayuthaya . --

Rescheduling & campaigns to cope with re-emergences

1995 – 2004 2005 – 2014

National immunization program Pa

ralle

l tim

elin

es

1995 DTP-HB pilot in Chiangrai

1994 NID started for polio eradication

1997 last case of polio in Thailand 1997 MMR introduced countrywide

2000 JE introduced countrywide

2005 dT replaced TT 2008 DTP-HB all prov.

2008 Flu for risk pop.

2010 vaccine supply by NHSO . --------------------

2011 pilot on Rota started in Sukhothai . ---------

2014 pilot on HPV started in Ayuthaya . --

Rescheduling & campaigns to cope with re-emergences

1995 – 2004 2005 – 2014

Vaccine development & production

Para

llel t

imel

ines

Mahidol maintaining continuous dengue vac development

GPO shifted JEV from Nakayama to Beijing strain GPO attempted LAV-JE, aborted

GPO stopped DTP to improve GMP

GPO constructingFlu manufacture

NSTDA & TCELS supporting dengue vac

GPO’s LAIV H1N1 licensed, H5N2 in clinical trials

TRCS maintaining BCG production TRCS upgrading BCG production

Bionet-Asia established as first private sector developer & producer, making continuous progress

Deve

lopm

ent

Prod

uctio

n GPO-MBP supplying EPI

Attempts on TB, Chik, EV7

Historical phase III HIV trial

1995 – 2004 2005 – 2014

Vaccine development & production

Para

llel t

imel

ines

Mahidol maintaining continuous dengue vac development

GPO shifted JEV from Nakayama to Beijing strain GPO attempted LAV-JE, aborted

GPO stopped DTP to improve GMP

GPO constructingFlu manufacture

NSTDA & TCELS supporting dengue vac

GPO’s LAIV H1N1 licensed, H5N2 in clinical trials

TRCS maintaining BCG production TRCS upgrading BCG production

Bionet-Asia established as first private sector developer & producer, making continuous progress

Deve

lopm

ent

Prod

uctio

n GPO-MBP supplying EPI

Attempts on TB, Chik, EV7

Historical phase III HIV trial

Veterinary vaccine manufacture under DLD

National Bio-pharma Center

(NBF)

1995 – 2004 2005 – 2014

Policy coordination mechanisms

Para

llel t

imel

ines

1992 MOPH appointed committee on national vaccine capacity advised bidding for IVI in Thailand, setting up NVI as IVI counterpart

1995 – 2004 2005 – 2014

Policy coordination mechanisms

Para

llel t

imel

ines

1992 MOPH appointed committee on national vaccine capacity advised bidding for IVI in Thailand, setting up NVI as IVI counterpart

MOPH submitted a proposal to UNDP inviting IVI establishment in Thailand.

1995 – 2004 2005 – 2014

Policy coordination mechanisms

Para

llel t

imel

ines

1992 MOPH appointed committee on national vaccine capacity advised bidding for IVI in Thailand, setting up NVI as IVI counterpart

MOPH submitted a proposal to UNDP inviting IVI establishment in Thailand.

1995 – 2004 2005 – 2014

Policy coordination mechanisms

Para

llel t

imel

ines

1992 MOPH appointed committee on national vaccine capacity advised bidding for IVI in Thailand, setting up NVI as IVI counterpart

MOPH submitted a proposal to UNDP inviting IVI establishment in Thailand.

1995 – 2004 2005 – 2014

Policy coordination mechanisms

Para

llel t

imel

ines

1992 MOPH appointed committee on national vaccine capacity advised bidding for IVI in Thailand, setting up NVI as IVI counterpart

MOPH submitted a proposal to UNDP inviting IVI establishment in Thailand.

1990’s - meetings & workshops on national mechanism for vaccine policy and capacity

NVC appointed by Cabinet , NVC secretary office in DDC/MOPH

1995 – 2004 2005 – 2014

Policy coordination mechanisms

Para

llel t

imel

ines

1992 MOPH appointed committee on national vaccine capacity advised bidding for IVI in Thailand, setting up NVI as IVI counterpart

MOPH submitted a proposal to UNDP inviting IVI establishment in Thailand.

1990’s - meetings & workshops on national mechanism for vaccine policy and capacity

NVC appointed by Cabinet , NVC secretary office in DDC/MOPH

2005 Government approved national vaccine strategic plan proposed by NVC/MOPH

2011 - NVI in DDC

2012 - NVI as PSO

มุมมอง / ภาพรวม• Gaps in vaccine security• Past records of successes• Potential capacities in

multi-sector partners • Huge enthusiasms for

development and cooperation • Ongoing efforts• Challenges

• Policy coordination & support• Human resource development• Trust & team work • Regional competition &

cooperation

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