14

1

bloodcoagulation1-2

(blood clotting factor) 13F VIF Va 12)

Ca2+ F IIIF K a

F XIII XIII

a. b. c.

aVaCa2+

1

1

2APTT activated partial thromboplastin time,APTT

APTT

1 0.109mol/L1:93000r/min510min24%-ACT30.025mol/L

1-0.1ml37C3min20.025mol/L0.1ml2

373.3(31.543.5)s37.52.8(3243)s10s

123h3min345APTT6APTT 1995International Committee of Thrombosis and Haemostasis,ICTHICSHAPTT

APTT15%30%1APTT 10sC25%25%DIC

2. APTT DIC3. APTTAPTTAPTT1.53.0

2

//TF

12PT

PTVX

PT12KK3

1 150mg2.5ml3710min20.025mol/L CaCl2

1109mmol/L0.1mol/L0.2ml1.8ml210.1ml370.1mlCaCl23723

1214s

1PT 214h 3371

3s1PTI

DIC

3

23961422-41165

141420-453-10LMP1996-06-15

3696/22/13/8kPa96//61/444cm39cm33cm27cm

RBC3.361012/LHb101g/LWBC3.24109/LPLT370109/LNa140mmol/LK4.1 mmol/LCl108 mmol/LGlu4.8 mmol/LBUN7.3 mmol/LCr89umol/LAST32U/L,ALT29 U/L,LDH122U/L,TBIL19.8 umol/LDBIL10.2 umol/LIBIL9.6 umol/LKPTT98.540PT1513TT1312CT1025FIB3 g/ L24 g/L1/5129203182.913335SmANADNAESR38mm/hIgG16.84g/LIgA2.69g/LIgM1.12g/LC3 0.44 g/LC4 0.32 g/LLEB

123

(Hemophilia)AHGPTCPTA

:X30

X1

1 V111C124

PCT2520KPTT354510STGT101415

STGTBiggs TGT)

C22562545

2KPTTSTGT

Von WillebrandVwR:WFRAg:RWFR:RCFR:WFBTR:WFGB:CR:Ag:C:Ag