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14. DF<< iv. =&'4(6' I&,4010))+ O,4)YT-)?,X ,-Y)%( +%,*5Y %6Y)Y9)(2 6'.,&'5,&)(2 1,*6Y130)?.

GX'")+'$)+1. In vitro. S'.,&'5,&)8 1Y'7),*5(%8 1,*6Y1(6( «IY1 /Y%&,*%,I,/». ",6,4)' 50/' ),/0&' !*08%&'-X)*?%,7, Y)N,&/'-Y:),-')'6Y5(9),7, 4(1'))+ «A01(9)(: *4Y5» 4Y1 4Y1 20.06.2011. (",6,4)8 50/8 ),/0&' IY17,584'6' D. P)04*?%'). [K60%5&,))(: &0*8&*]. — H03(/ 1,*58I8: http://medsvit.org/articles/1/76/in-vitro/.

2. 9:('-3 *.+. D683.' %6()(90*%,: 6'.,&'5,&),: 1('7),*5(%(: )'*5,+[00 ( I0&*I0%5(4; // A01(9)' 7'O05' «R1,&,4’+ $%&'X)(». — F(X4. — 2008. — M 1. — D. 47. [K60%5&,))(: &0*8&*]. — H03(/ 1,*58I8: http://health-ua.com/articles/2335.html.

3. #$%&'()% !."., ,-)%- *.+. A05&,6,7Y9)0 O'.0O-I090))+ 6'.,&'5,&),X /01(-()( $%&'X)(: *5'), I&,.60/(, T6+2( 4(&YT0))+ // C'8%,4Y I&'-Y VII AY3)'&,1),X )'8%,4,-502)Y9),X %,)N0&0)-YX «A05&,6,7Y+ 5' 4(/Y&U4'6?)' 502)Y%' (A05&,-6,7Y+-2010)», 12–14 3,45)+ 2010 &. — $ 2-2 55. — L,/ 1. — D. 113–116.

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5. !%$%I>%- !.!. <,*4Y1 I&,4Y1)(2 %&'X) *4Y58 4 8I&'46Y))Y *N0&,U ,2,&,)( O1,&,4’+ // Z,&8/ I&'-4'. — 2011. — M 2. — D. 139–146. [K60%5&,))(: &0-*8&*]. — H03(/ 1,*58I8: http://www.nbuv.gov.ua/ e-journals/FP/2011-2/11vvvcoz.pdf.

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7. Kenny D, Fraser CG, HyltoY Petersen P, Kallner A. Strategies to set global quality specid cations in labora-tory medicine, Stockholm, 24—26 April 1999. Consen-sus agreement// Scand J Clin Lab Invest 1999;59:585.

=M4FBD)N DM8OB;)LDMP QB4R =)=;NOR CS)D)TN=C)G SBQM8B;M8DRG )==SNFMLBD)P L !C8B)DNL. D. >#3@$/23, B. -. ).23., O. L. ;J<'&/+ , Q.UB. 8373?&/, B. -. S9/$.+, B.Q. G$1(3562&1 D5'5?+ I,*4+[0)' 4,I&,*'/ *,O1')(+ ),&/'-5(4),: .'O; %6()(90*%(2 6'.,&'5,&);2 (*60-1,4')(: 4 $%&'()0. >)'6(O *6,3(4T0*+ *(58'--(( I,%'O;4'05 )0,.2,1(/,*5? *,O1')(+ *0&(( *5')1'&5,4 D(*50/; %6()(90*%(2 1('7),*5(90-*%(2 (**601,4')(: in vitro (F6()(90*%,: 6'.,-&'5,&),: 1('7),*5(%(). H'**/'5&(4'05*+ I&01-6'7'0/;: =&,0%5 *5')1'&5' * ,*),4);/( I,6,-30)(+/( I, *,O1')(U 5'%,: *(*50/; ( 00 ,*),4);0 N8)%-(,)'6?);0 J60/0)5;.C(J"$.0$ 6(3.+: %6()(90*%'+ 6'.,&'5,&)'+ 1('7),*5(%', *(*50/'%6()(90*%(2 6'.,&'5,&-);2 (**601,4')(:, ),&/'5(4),0 &0786(&,4')(0, *5')1'&5(O'-(+.

CREATING REGULATORY FRAMEWORK FOR CLINICAL LABORATORY EXAMINATIONS IN THE UKRAINEV.M. Procenko, A.G. Ivkov, M.V. Tyukhtina , B.A.URogozhyn, G.G. Lunyova, O.L. Kheilomskyj Article is devoted to creating the regulatory framework of clinical laboratory examinations in the Ukraine. Analysis of the situation shows the need for a series of standards System of clinical diagnostic examinations in vitro (Clini-cal Laboratory Diagnostics). the proposed drae standard with the basic provisions on the establishment of such a system and its main functional elements is considered.Keywords: *linical laboratory diagnostics, clinical lab-oratory examinations system,normative regulation.

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GX'")+'$)+1. ISO GUIDE 99 International vocabulary of me-trology — Basic and general concepts and associated terms — VIM (AY3)'&,1)(: *6,4)(% /05&,6,7YX — #*),4)Y 5' O'7'6?)Y I,)+55+ 5' I,4’+O')Y O )(/( 50&/Y)( (VIM)).

2. Taylor J.K. Standard reference materials: Hand-book for SRM users. NIST Special Publication 260 –100, 1985 Edition (Issued February 1993 U.S. Department of Commerce). 104 P).

3. QUALITY HANDBOOK. [K60%5&,))(: &0-*8&*]. — H03(/ 1,*58I8: http://qh.siteedit.ru/35.

4. ISO 17511:2003 In vitro diagnostic medical devices — Measurement of quantities in biological samples — Metrological traceability of values assigned to calibrators and control materials (A01(9)Y 4(&,.( 16+ in vitro 1Y'7),*5(%( — !(/Y&U4'))+ 406(9() 4 .Y,6,7Y9)(2 I&,.'2 — A05&,6,7Y9)' I&,*5038-4')Y*5? O)'90)?, I&(I(*84')(2 16+ %'6Y.&'5,&Y4 5' %,)5&,6?)(2 /'50&Y'6Y4).

5. JCTLM database: Laboratory medicine and in vitro diagnostics http://www.bipm.org/jctlm/advancedSearch.do (@'O' 1')(2 #.’\1)'),7, %,-/Y5058 O I&,*50384'),*5Y 8 6'.,&'5,&)Y: /01(--()Y).

6. <DL$ ISO/IEC 17025:2006 R'7'6?)Y 4(/,7( 1, %,/I050)5),*5Y 4(I&,.84'6?)(2 5' %'6Y.&8-4'6?)(2 6'.,&'5,&Y:.

7. ISO 18153:2003 In vitro diagnostic medical devices — Measurement of quantities in biological samples — Metrological traceability of values for catalytic concentration of enzymes assigned calibrators and control materials (A01(9)Y 4(&,.( 16+ in vitro 1Y'7),*5(%( — A05&,6,7Y9)' I&,*50-384')Y*5? O)'90)?, %'5'6Y5(9),X %,)-0)5&'-YX N0&/0)5Y4, I&(I(*84')(2 16+ %'6Y.&'5,&Y4 5' %,)5&,6?)(2 /'50&Y'6Y4).

8. ISO 15193:2009 In vitro diagnostic medical devices — Measurement of quantities in samples of biological origin — Requirements for content and presentation of reference measurement procedures (A01(9)Y 4(&,.( 16+ in vitro 1Y'7),*5(%( — !(-/,7( 1, O/Y*58 Y I,1'4'))+ &0N0&0)5)(2 4(/Y&U-4'6?)(2 I&,-018&).

9. ISO 15194:2009 In vitro diagnostic medical devices — Measurement of quantities in samples of biological origin — Requirements for certified reference materials and the content of supporting

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10. DIRECTIVE 98/79/EC OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 27 Oc-tober 1998 on in vitro diagnostic medical devices //OJ L 331, 7.12.1998, p. 1 (<(&0%5(4' 98/79/KD b4&,I0:*?%,7, ='&6'/0)58 5' H'1( 4Y1 27 3,45)+ 1998 &,%8 [,1, 4(&,.Y4 16+ in vitro 1Y'7),*5(%().

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PROBLEMS OF STANDARDIZATION IN METROLOGY OF CLINICAL LABORATORY EXAMINATIONS

A.G. Ivkov, M.V. Tyukhtina , V.M. Procenkof e following article is devoted to the problems in metrology clinical laboratory examinations. f e ur-gent tasks of metrology standardization are recog-nized: creating nationally certid ed reference materi-als composition and properties of samples, , creating metrological traceability from low-level reference materials (calibrators and control materi-als) to reference materials and methods upper lev-els, setting of analytical performance requirements, verid cation and validation of clinical laboratory ex-aminations, establishing rules for quality control of qualitative and quantitative clinical laboratory ex-aminations, establishing rules for the external qual-ity assessment.Keywords: clinical laboratory diagnostics, clinical laboratory examinations , metrological traceability, standardization.

"O<JC9=CB8; CU ILDT 8<T76=6SCN<-B:CT C7B8C8D86L, WL<YJ9FB:6S6 ><I<F9=M76S6 C Q9BB9NDB<8B:6S6, OFCIDH9=C S<7<8CN<B:CY :6I, :6-86F;Y, L 8<6FCC, H6X76 6O86H L7<IFP8M L :=<8:C 6FS97CUH9 O9-JC<789. ^89 O6B=<I6L98<=M76B8M S<76L B79N9=9 OFCB8DO9<8 : OF6-L<F:< T6UPYB:6Y :=<8:C. #B=C 89 6:9U;L9<8BP F9:6L6Y, :6I U9OD-B:9<8 OF6J<BB 9O6O86U9 — B9H6D-ECYB8L9, 79 :686F6< 6E;N76 F9:6-L;< :=<8:C 7<BO6B6E7;./=VN : CUECF98<=M76B8C — 979-=CU DF6L7P _:BOF<BBCC HC-

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6OF<I<=C=C OP8M HC:F6($/, N9B8M :686F;T L HeLa OFCBD8B8LD-V8 79 6N<7M L;B6:6H DF6L7<, 9 N9B8M, 79OF68CL, 79 6N<7M 7CU-:6H. ^868 D7C:9=M7;Y OF6>C=M 79I]X76 68=CN9<8 I977;< F9:6-L;< :=<8:C 68 UI6F6L;T..6 C7>6FH9JCC ScienceDaily, EC6-=6SC L7<IFC=C BC78<8CN<B:CY :6I :9: L :=<8:C HeLa, 89: C L 6E;N-7;<. .F6L<FCL O6I6O<N7DV :=<8-:D O6 LB<H OP8C >9:86F9H, S<7<-8CN<B:9P BT<H9 OFCT6IC=9 : L<F-76HD L;L6ID: :=<8:C HeLa E;=C DEC8;, 9 UI6F6L;< 6B89=CBM J<=;.

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GX'")+'$)+1. <DL$ ISO/IEC 17025:2006 R'7'6?)Y 4(/,7( 1,V4(I&,.84'6?)(2 5' %'6Y.&84'6?)(2 6'.,&'-5,&Y:.

2. <DL$ ISO/IEC 17011:2004 #-Y)U4'))+ 4Y1-I,4Y1),*5Y. R'7'6?)Y 4(/,7( 1, ,&7')Y4 '%&01(5'--YX, [, '%&01(58U5? ,&7')( O ,-Y)U4'))+ 4Y1I,-4Y1),*5Y.

3. EA-3/04 2001 Use of prod ciency testing as a tool for accreditation in testing

4. EA-2/10 2001 EA Policy for Participation in Na-tional and International Prod ciency Testing Activities.

5. ILAC-G22:2004 Use of Prod ciency Testing As a Tool For Accreditation In Testing.

6. ILAC-P9:2005 ILAC Policy for Participation in Prod ciency Testing.

7. EA-4/18:2010 Guidance on the level and fre-quency of prod ciency testing participation.

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8. ILAC-G13:08/2007 ILAC Guidelines for the Re-quirements for the Competence of Providers of Pro-d ciency Testing Schemes.

9. ISO/IEC 17043:2010 Conformity assessment — General requirements for prod ciency testing.

10. ISO/IEC 15189:2007 Medical laboratories — Particular requirements for quality and competence.

11. European Prod ciency Testing Information Sys-tem (EPTIS) http://www.eptis.bam.de

12. ISO Guide 34:2009 General requirements for the competence of reference material producers.

13. ILAC-G12:2000 Guidelines for the Require-ments for the Competence of Reference Materials Producers.

14. ISO Guide 31:2000 Reference materials — Contents of certid cates and labels.

15. ISO Guide 35:2006 Reference materials — General and statistical principles for certid cation.

16. <DL$ "#DL ED# 5725-1:2005 L,9)Y*5? (I&'4(6?)Y*5? Y I&0-(OY:)Y*5?) /05,1Y4 5' &0O86?-5'5Y4 4(/Y&U4'))+. — _. 1–6.

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ARRANGEMENT AND OPERATION OFUPROFICIENCY TESTINGV.N. Chekalin, A.A. Lykin, I.V. GogomanProd ciency testing (PT), from the one hand, is a re-quirement of ISO/IEC 17025, and from the other hand, is a requirement of ISO/IEC 17011 and EA-03, as well as policies of National Accreditation Agency of Ukraine (NAAU) as national accredita-tion body formulated according to EA-2/10, ILAC-G22 and ILAC-P9, is crucial and objective accredi-tation criterion. f e criterion gets especial signid cance for those types of testing where it is practically impossible to achieve traceability of measurement results using other means in particu-lar as for chemical, microbiological, biochemical tests. f at is why the base for achievement of trace-ability of test results is using reference materials both for internal quality control, and external qual-ity control methods such as PTS. f e paper de-scribes the normative base, requirements for pro-viders and reference materials for arrangement and operation of PTS, the experience in utilization of re-sults of participation of laboratories in PTS for ac-creditation purposes.Key words: accreditation, competence, laboratory, prod ciency testing, reference materials, PT provider, traceability.

>#3 +.'3#K.B')3?2( !%?%O8@8$ "8)%?3>%-8E, 1,%5. 502). )'8%, ",6,4' C>>$, v_chekalin@naau.org.ua98)2( <?')A3(O$ <?')A3(O$%-8E, )'9'6?)(% 8I&'46Y))+ '%&01(5'-YX 6'.,&'5,&Y: C>>$, lykin@naau.org.ua+%6%@3( ,6%$ !%?%O8@8$%-8E, %')1. 2Y/. )'8%, 7,6,4)(: *IY4&,.Y5)(% 4Y11Y68 '%&01(5'-YX 6'.,&'5,&Y: C>>$, gogoman@naau.org.ua

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<6+ I,4;T0)(+ .(,*,4/0*5(/,*5( ( 1,67,409),*5( .(,I&,50O,4 %6'I'),4 *0&1-' 40105*+ &'O&'.,5%' )'),502),6,7(90*%(2 /0-5,1,4 )')0*0)(+ I,%&;5(: (O I(&,8760&,1' )' (2 *54,&%(. <6+ *()505(90*%(2 I&,50O,4 %&,40),*);2 *,*81,4 ( ,1),&'O,4;2 (O10-6(:, %,)5'%5(&8U[(2 * %&,4?U, *,O1'U5*+ )'),502),6,7(90*%(0 /05,1; /,1(N(-(&,-

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4')(+ I,40&2),*5( )'I;60)(0/ I(&,6(5(-90*%,7, )'),8760&,1' 16+ 8*,40&T0)*54,4'-)(+ N8)%-(,)'6?);2 *4,:*54 (O106(:. G-'")+'$)+1. Goodman S.L., Tweden K.S. et al. Platelet interaction with pyrolytic carbon heart-valve leam ets // J.Biomed. Mater. Res, 1996. — Vol. 32. — H. 249–258.

2. <$?%-A)8> #.L., +$8&'()% !.!., R0('- *.P., H--O%)8@%- C.!., +3-$8?'()%- !.L. E*%8**540));0 %6'-I'); *0&1-'. =,1 &01'%-(0: '%'10/(%' H>AC h0490)%, ].S. — D=..: R># «#SA> A01(' "&8II», 2007. — 448 *.

3. R$'E)% !.J. D,4&0/0));0 (*%8**540));0 %6'I'); *0&1-' // >6?/')'2 %6()(90*%,: /01(--();, 2006. — M12. — D. 138–138.

4. 4'?%A1%&)8> !.]., J%-8)%- !.F. F6()(90*%,0 (*I,6?O,4')(0 ,5090*540)),7, 148*54,&9'5,7, (*%8**540)),7, %6'I')' *0&1-' «A01()3» // !0*5)(% '&(5/,6,7((, 2001. — M 21. — D. 63–68.

5. !%?)%- +."., .313$8(%- !.Q. @(,()30)0&);: I,50)-('6 8760&,1' // C'),502)(%', 2007. — M 10. — D. 52–56.

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11. F3(/)%- !.J., C1$')3?%-A)3U *.P. 8 O$. A'-50&('6; 16+ *,4&0/0)),: /01(-();: $90.),0 I,*,.(0. — #&0).8&7: "#$ #"$, 2004. — 113 *.

12. H-O%)8@%- C.!., ":>S'@(') *.R., .313$8(%- H.Q. 8 O$. E**601,4')(0 N'%5,&,4, 46(+U[(2 )' )'-103),*5? I&,50O,4 %6'I'),4 *0&1-' (O I(&,6(5(90-*%,7, 8760&,1' // L0O. 1,%6. ( *,,.[. V`` !*0&,*. *W0O1' *0&109),-*,*81(*5;2 2(&8&7,4, 2001. — D. 23.

13. #%M%- !.!., +%$O''- C.F., +$'E8(A)3U *.!. c60%5&(90*%(0 ( 50&/,J60%5&(90*%(0 *4,:*54' )'),I,&(*5,7, 8760&,1' // Z(O(%' 540&1,7, 506', 2002. — L,/ 44. — !;I. 4. — D. 758–761.

14. L02),6,7(90*%(: I&,-0** )')0*0)(+ 8760-&,1),7, I,%&;5(+ )' I,40&2),*5? %,&,)'&);2 *50)5,4 // F'5'6,7 ()),4'-(,));2 I&,0%5,4 ( &'O&'.,5,% (4;I8*% 104+5;:). =,1 ,.[0: &01'%--(0: 1.5.). =60*%'904*%,7, ].A. — A()*%, @06,-&8**%(: ()*5(585 *(*50/),7, ')'6(O' ( ()N,&-/'-(,)),7, ,.0*I090)(+ )'89),-502)(90*%,: *N0&;, 2003. — D. 79.

15. Butany J., Ahluwalia M.S., Munroe C., Fayet C., Ahn C., Blit P., Kepron C. et al. Mechanical heart valve prostheses: identid cation and evaluation (erratum). // Cardiovascular Pathology, 2003. — Vol. 12. — Issue 6. — P. 322–344.

16. F6'I'); *0&1-' (*%8**540));0 ',&5'6?);0 «=6')(%*-L» // F'5'6,7 ()),4'-(,));2 I&,0%5,4 ( &'O&'.,5,% (4;I8*% 104+5;:). =,1 ,.[0: &01'%--(0: 1.5.). =60*%'904*%,7, ].A. — A()*%, @06,-&8**%(: ()*5(585 *(*50/),7, ')'6(O' ( ()N,&-/'-(,)),7, ,.0*I090)(+ )'89),-502)(90*%,: *N0&;, 2003. — D. 225.

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APPLICATION OF PYROLYTIC NONCARBON IN ARTIFICIAL HEART VALVESV.B. Maksimenko, M.M. SychikAnalyzed was the literature data concerning nano-structured pyrolytic carbon, a poorly studied biocom-patible structural material, which is he most popular material available for artid cial mechanical heart valves. Presented are the overview about the current market of the pyrolytic carbon heart-valve leam ets.Key words: artid cial heart valve, nanomaterials, pyrocarbon, biocompatibility.

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14. N'-E'()% R9., 4%I$%- 9.9., <I$'S3( *.+. <('*5,6(90*%'+ N8)%-(+ 604,7, 30681,9%' *0&1--' // A.: "c#L>H—AK<. — 2002. — 240 *.

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FUNDAMENTAL STUDIES IN CARDIAC SURGERY

G.V. Knyshov, E.V. R9bakovaNew fundamental studies in cardiac surgery are presented: the problem of an organism life support with the use of an artid cial organs; mathematical model creation of the closed blood circulation sys-tem, which includes damping system and a vessel work as a «second heart». f e study about «band type» of lee ventricle myocardium structure and its helical type of contraction, as a separate fragment of universal theory of the world examined. New opin-ion about myocardium anatomy permits to study pathogenesis of hypertrophic and dilated cardiomy-opathies. It is showing that the study of tortuous coronary arteries is perspective. It is proved the use of general guided artid cial hyperthermia positively inm uences the immune state in the treatment of acute infective endocarditis. Application of new fundamental scientid c elaborations permitted to decrease hospital mortality to 1.5 % in 4.5–5 thou-sands cardiac operations performed annually.

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ANALYSIS OF THE FUNCTIONAL STATE OFUTHE CIRCULATORY SYSTEM ANDUMICROVASCULATURE BED BASED ONUARTERIAL PRESSURE AND HEART RATE PARAMETERSE.A. Nastenko, E.K. Nosovets, S.V. ZubkovUsing the consecutive clinical measurements and daily monitoring of blood pressure and heart rate the functional relationships of diastolic and systolic arterial pressure and also the diastolic pressure on heart rate were investigated. f e diagrams of rela-tionships of these parameters were built and the dy-namics of arterial pressure and heart rate of healthy persons and persons with circulatory failure and ar-terial hypertension were analyzed. f e diagrams obtained can be used for noninvasive diagnostics ofVheart failure and microcirculatory bed functional state and also for estimation the eo ectiveness of their correction. f e clinical eq ciency of this ap-proach was investigated. Keywords: Circulatory system, arterial pressure, heart rate, microcirculatory system, cluster analysis.

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203. 3. .5 HDXNC7 16–17 =<8 (XCF76Y =C7C<Y L;I<=<79 DBF<I7]779P .5)

203. 8. .D=MB6L;< L6=7; X<7\C7 16–17 =<8

203. 7. .D=MB6L;< L6=7; HDXNC7 60–70 =<8

203. 6. .D=MB6L;< L6=7; HDXNC7 50–60 =<8

203. 4. .D=MB6L;< L6=7; HDXNC7 20–30 =<8

203. 5. .D=MB6L;< L6=7; HDXNC7 30–50 =<8

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203. 10. .D=MB6L;< L6=7; X<7\C7 30–50 =<8

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203. 13. "6O6B89L=<7C< BF<I7CT L6=7 LB<T L6UF9B87;T SFDOO X<7\C7

203. 14. "6O6B89L=<7C< BF<I7CT L6=7 HDXNC7 C X<7\C7 16–20 =<8

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203. 16. "6O6B89L=<7C< BF<I7CT L6=7 HDXNC7 C X<7\C7 30–50 =<8

203. 17. "6O6B89L=<7C< BF<I7CT L6=7 HDXNC7 C X<7\C7 50–60 =<8

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G-'")+'$)+1. C-'1?%-3 9.L. #/,6'3(4'U['+ 7(/)'*5(%' 16+ *0&1-' ( *,*81,4. — F., 2010. — 176 *.

2. F%$%1;)% +.Q. Z(O(,6,7(+ 906,40%'. — L,/ 1. — F.: A01(-()', 1997, 448 *.

3. [A *.P. @'6?)0,50&'I(+ ( 4,O&'*5. — F.: C'8-%,4' 18/%', 1985. — 136 *.

4. Jane F. Reckelhoff Gender Differences in the Regulation of Blood Pressure /4 Jane F. Reckelhoo // Hypertension, 2001. — M 37. — P. 1199–1208.

5. L02)(90*%(0 2'&'%50&(*5(%( I86?*,%*(/0-5&' ]L>D#FDE-200: www.utasco.com

6. <()'/Y9)' I86?*,4' 1Y'7),*5(%' / <06'4'& F-A., R'I,&,3%, `.#., R8.98% !.`., D%,&(% #.!., L%'90)%, !.S. // c60%5&,)(%' ( *4+O? — L0/'5(-90*%(: 4;I8*% «c60%5&,)(%' ( )'),502),6,7((», 2009. — _. 2. — C. 252–257.

7. C0:&,));0 *05( 4 *(*50/0 I86?*,4,: 1('7),-*5(%( / R8.98% !.E., P-0)%, !.=., <06'4'& F-A, D%,&(% #.!., R'I,&,3%, E.>. // c60%5&,)(%' ( *4+O?. — L0/'5(90*%(: 4;I8*% «=&,.60/; J60%-5&,)(%(», 2007. — _. 3. — C. 58–61.

8. DI0-('6(O(&,4'))'+ .'O' 1'));2 *(*50/; I86?*,4,: 1('7),*5(%( / R8.98% !.E., P-0)%, !.=., <06'4'& F-A, D%,&(% #.!., R'I,&,3%, E.>., F&0[8% !.>. // c60%5&,)(%' ( *4+O?. — L0/'5(-90*%(: 4;I8*% «=&,.60/; J60%5&,)(%(», 2007. —_. 2. — C. 108–111.

9. c%*I&0**-1('7),*5(%' I, 1'));/ I86?*,%*(-/05&(( / <06'4'& F-A., R'I,&,3%, E.>., R8.98% !.E. ( 1&. // c60%5&,)(%' ( *4+O?, 2008. — D. 145–150.

10. Recognition methods of polymetric human infor-mation research /Zaporozhko I.A., Zubchuk V.I., Scoric A.V. // Proceeding of 21 International CODATA confer-ence «Scientid c Information for Society — from Today to the Future» — Ukraine, Kyiv, 2008 — P 332–337.

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AGE AND GENDER PECULIARITIES OF A PULSE MEASUREMENTZaporozhko I.A., Zubchuk V.I., Nastenko E.A., Nosovets E.K.Attention was given to a problem of establishing a hu-man functional condition according to physiological parameters measurements of dio erent age groups of people. f e most informative parameters are cardio-vascular system measurements such as: arterial pres-sure (systolic and diastolic), heart rate, blood oxygen-ation and circulation dynamics of pulse waves. Pulse waves, measured on upper extremities vessels, give in-tegral information about cardiovascular system con-dition and condition of other related organs. f ere-fore the creation of express-diagnostic computer system based on analysis of cardiovascular system pa-rameters is an up to date task.Keywords: Aging, arterial pressure, pulseoximetry, cardiovascular system, gerontology, FourierVtransform, pulse.

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STEREOSCOPIC VISUALIZATION OFUBIOMEDICAL OBJECTSBubnov R.V., Kyselova O.G.Paper describes method of anaglyphV(stereoscopic) imagesVreconstructing for improve of medical imag-es interpretation and visualization.Key words: anaglyphVimage, biomedical object, three-dimensional model, stereoscopic pair.

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3. N3M%-3?%- !.". #*),4; 4)85&0))07, ,*50,-*()50O' / !. A. h'I,4'6,4, !. !. B,/()0-, D. !. A(2':6,4. — A.: "c#L>H — A01(', 2009. — 240 *.

4. Helical blade versus sliding hip screw for treat-ment of unstable intertrochanteric hip fractures: a biomechanical evaluation. / [Strauss E., Frank J., Lee J., Kummer F.J., Tejwani N.] // Injury. — 2006. — Oct. — Vol. 37(10). — P. 984–989.

5. A prospective trial comparing the Holland nail with the dynamic hip screw in the treatment of inter-trochanteric fractures of the hip. / [ N. J. Little, V. Ver-

ma, C. Fernando, D. S. Elliott, A. Khaleel]. // Journal of Bone and Joint Surgery - British Volume. — 2008. — Vol. 90-B . — Issue 8. — P.1073–1078.

6. Mechanical evaluation of unipolar hip spacer constructs. / Kummer F.J., Strauss E., Wright K., Ku-biak E.N., Di Cesare P.E. // Am. J. Orthop. — 2008. — Oct. — Vol. 37(10). — P. 517–518.

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N.Shidlovskyf e results of the experimental study on deformation of the d xation systems, used for treatment of the limb fractures, are presented in the article. Dio erent meth-ods are analyzed. Practical guidelines for choice of the optimal d xation devices are given. f e stio ness of the bone-apparatus system was considered as the main criterion of quality as well as mutual disloca-tions of the bone fragments.Key words: biomechanics, lower extremity, deforma-tion, stio ness of d xation, osteosynthesis, full-scale simulation.

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COMPUTER ANALYSIS ALGORITHM OF ULTRASONIC DIGITAL IMAGESKomissarova E.V., Orel V.E.A method for digital processing and computer analy-sis of digital ultrasound images based on the calcula-tion of the spatial autocorrelation by Moran to quan-tify the pattern of the image. Used the programming language JAVA, which allowed to analyze original images on standard DICOM. f e object of the study was the ultrasound imaging of the liver. Conducted aVcomputer analysis of digital ultrasound images ofVpatients with pathology of viral hepatitis of various forms, has shown the feasibility of further clinical testing using the developed algorithm and computer programs.Key words: heterogeneity, entropy, Java, ultrasound, computer analysis, viral hepatitis, a correlation analysis.

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2. Delavar-K.M., Zaporozhko I.A., Zubchuk V.I. Recognition Methods of Polymetric Human Informa-tion Research // Proceedings of International Scien-tid c-Practical Conference «Virtual Instruments In Biomedicine 2009», Klaipeda, 2009. — P. 263—267.

3. R8.98% !.E., <81%, D.]., F,/'& >.". E10)5(-N(%'-(+ /05,1,/ C'%'5')( *601,4;2 JNN0%5,4 4,O10:*54(+ 50&'I045(90*%,7, /'7)(5),7, I,6+ )' ,&7')(O/ 906,40%' // c60%5&,)(%' ( *4+O?. — !;I. 22. — F(04, 2004. — D. 73—75.

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METHODS AND TOOLS FOR EVALUATING THE EFFICIENCY OFUMAGNETOTHERAPEUTIC PROCEDURES M. Delavar-Kasmai, I.A. Zaporozhko, V.I. Zubchuk, V.V. Shlykov, I.V. BondarenkoFor an estimation of eq ciency of inm uence the mag-netic d eld on the patient a method of an estimation ofVeo ects of the deferred action under inm uence by aVmagnetic d eld is oo ered. f e method based on cal-culation of index of the form and normalized of index ofVthe amplitude-phase which is calculated on the ba-sis of harmonious structure of a signal of pulse waves. Adequacy of the suggested criteria of an estimation ofVeq ciency which are measured on method Naka-tani is cond rmed.Keywords: magnetic d eld, pulse waves, method Nakatani.

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DEVICE FOR SIMULTANEOUS PULSATING INTRAPERICARDIAL HEART SUPPORTV.B Maksimenko, Y.A. Kravchuk, L.D. Tarasova National Technical University of Ukraine «KPI»N.M. Amosov National Institute of Cardiovascular SurgeryAbstract. f e analysis of existing models to support cuo pumping function of the heart. A model of the lower heart in CAD-program. Developed their own design to the pneumatic cuo intrapericardial device. Constructed of force pressures arising under the cuo on the surface of the ventricles. f e inm uence of cuo on coronary heart mesh.Keywords: cuo , coronary mesh, biomechanics of the heart, the ventricles of the heart, synchronization.

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12. $*5&,:*54, 16+ (O7,5,460)(+ '5&'4/'5(90-*%(2 (76 / >.>.h'.'T,4. >.". R'6'O()*%(: // I'-50)5 RU M 2203761, B21D53/00, B21D7/028. #I8.6. 10.05.2003.

13. DI,*,. (O7,5,460)(+ '5&'4/'5(90*%(2 ,N-5'6?/,6,7(90*%(2 (76/ C.E.@'%8),40-, K.>. A'5-4004 // I'50)5 RU M 2218879, A61B17/06, A61F9/007. #I8.6. 20.12.2003.

14. DI,*,. (O7,5,460)(+ *50&3)0: '5&'4/'5(-90*%(2 (76 / S.R. #&1')*%(:, @.E. =,I,4, !.C. H0O-)(%,4, !.D. h'I%(), ].D. E6?(), !.>. h5'%7'8O // I'50)5 RU M 2055527, A 61B 17/06. #I8.6. 03.10.1986.

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16. Device for forming bores and a method for form-ing bores by eyeless sewing needles / Katoh Kazuaki [Jp]; Matsutani Kanji [Jp] //I'50)5 WO M 2010038683, A61B17/06; B21G1/02. #I8.6. 08.04.2010.

17. Method of attaching a suture (84) to a needle barrel / Stametz Jerry [Us]; Price John [Us]; Reynolds Eugene [Us]; Barsch Kenneth [Us] // I'50)5 WO M 2010068566, A61B17/06. #I8.6. 17.06.2010.

18. >5&'4/'5(90*%'+ (76' / !.<. g0&.'%,4, >.!.VB'%(/,4 // I'50)5 RU M 66178, >61!17/06.#I8.6.10.09.2007.

19. >5&'4/'5(90*%'+ (76' / >.E. D%&0.-,4, !.".VF'&'.')? // I'50)5 RU M 2045932, A61B17/06. #I8.6. 20.10.1995.

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A METHOD OF MAKING ATRAUMATIC NEEDLES

A. Tkachenko-TkalichDeveloped in the 90’s design of atraumatic needles allow Ukrainian products to compete with foreign manufacturers on the market of our country. f e purpose of work is compare methods of manufacture of atraumatic needle tips and recommendations on improving the setup for the formation of a needle.Key words: atraumatic needle, manufacturing tech-nology, treatment of metal, taperkat, cubanite circles.

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GX'")+'$)+1. IEC 62209. Human exposure to radio frequency d elds from hand-held and body-mounted wireless communication devices — Human models, instru-mentation, and procedures — Part 1: Procedure to determine the Specid c Absorption Rate (SAR) for hand-held devices used in close proximity of the ear (frequency range of 300 MHz to 3 GHz).

2. IEC 62233. Measurement methods for electro-magnetic d elds of household appliances and similar apparatus with regard to human exposure.

3. IEC 62311. Assessment of electronic and electri-cal equipment related to human exposure restrictions for electromagnetic d elds (0 Hz – 300 GHz).

4. IEC 62577. Evaluation of human exposure to electromagnetic d elds from a stand-alone broadcast transmitter (30 MHz – 40 GHz).

5. ITU-T Recommendation K.52. Guidance on complying with limits for human exposure to electro-magnetic felds.

6. ITU-T Recommendation K.61, Guidance on measurement and numerical prediction of electro-

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magnetic d elds for compliance with human exposure limits for telecommunication installations.

7. EN 50360. Product standard to demonstrate the compliance of mobile phones with the basic restric-tions related to human exposure to electromagnetic d elds (300 MHz – 3 GHz).

8. EN 50383. Basic standard for the calculation and measurement of electromagnetic d eld strength and SAR related to human exposure from radio base sta-tions and d xed terminal stations for wireless telecom-munication systems (110 MHz – 40 GHz).

9. EN 50385. Product standard to demonstrate the compliance of radio base stations and d xed terminal stations for wireless telecommunication systems with he basic restrictions or the reference levels related to man exposure to radio frequency electromagnetic d elds (110 MHz – 40 GHz) — General public.

10. EN 50401. Product standard to demonstrate the compliance of d xed equipment for radio transmission (110 MHz – 40 GHz) intended for use in wireless tele-communication networks with the basic restrictions or the reference levels related to general public expo-sure to radio frequency electromagnetic d elds, when put into service.

11. EN 50413. Basic standard on measurement and calculation procedures for human exposure to electric, magnetic and electromagnetic d elds (0 Hz – 300 GHz).

12. EN 50371. Generic standard to demonstrate the compliance of low power electronic and electrical ap-paratus with the basic restrictions related to human exposure to electromagnetic d elds (10 MHz–300 GHz) — General public.

13. EN 62209. Human exposure to radio frequency d elds from hand-held and body-mounted wireless

communication devices — Human models, instru-mentation, and procedures — Part 1: Procedure to determine the Specid c Absorption Rate (SAR) for hand-held devices used in close proximity of the ear (frequency range of 300 MHz to 3 GHz).

14. EN 62311. Assessment of electronic and electri-cal equipment related to human exposure restrictions for electromagnetic d elds (0 Hz – 300 GHz).

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LITERATURE REVIEW STANDARDS RELATED HUMAN EXPOSURE TO NONfIONIZING RADIATIOND. Diomin, PhD S. Kuznetsov, O. Kuznetsov, C.O+2+renkoDiscussed international and European standards forVnon-ionized radiation action(NOR) per person. Analyzed the situation with the standardization ofVthe topic in Ukraine.Keywords: standard, evaluation, assessment, measuring method.

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GX'")+'$)+1. Mantiply DM, Pohl KR, Poppell SW, Murphy JA. Summary of measured radiofrequency electric and magnetic d elds (10 kHz to 30 GHz) in the general and work environment. Bioelectromagnetics 18:563-577; 1997.

2. Henderson SI, Bangay MJ. Survey of exposure levels from mobile telephone base stations in Austra-lia. Biolelectromagnetics 27:73-76; 2006.

3. Cooper TG, Mann SM, Khalid M, Blackwell RP. Public exposure to radio waves near GSM microcell and picocell base stations. J Radiol Prot 26:199-211; 2006.

4. Durney CH, Massoudi H, Iskander MF. Radiofre-quency radiation dosimetry handbook (Fourth Edi-tion), USAFSAM-TR-85-73, USAF School of Aero-space Medicine, Brooks Air Force Base, TX 78235;1986.

5. Tam ove A, Hagness SC. Computational electro-dynamics: the d nite-dio erence time-domain method, 3rd edition, Norwood, MA. Artech House; 2005.

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6. Dimbylow PJ. Fine resolution calculations of SAR in the human body for frequencies up to 3 GHz. Phys Med Biol 47:2835-2846; 2002.

7. Wang J, Fujiwara O. Dosimetry in the human head for portable telephones. In: f e Review of Radio Science 1999—2002. WR Stone (ed). New York: Wi-ley:51—63; 2002a.

8. Kuster N, Balzano Q. Energy absorption mecha-nism by biological bodies in the near d eld of dipole antennas above 300 MHz. IEEE Trans. Vehicular Tech 41:17-23; 1992.

9. United Nations Environment Programme/World Health Organization/ International Radiation Protec-tion Association. Electromagnetic d elds (300 Hz to 300 GHz). Geneva: World Health Organization; En-vironmental Health Criteria 137; 1993.

10. Kuster N, Balzano Q. Energy absorption mech-anism by biological bodies in the near d eld of dipole antennas above 300 MHz. IEEE Trans. Vehicular Tech 41:17-23; 1992.

11. Tenforde, T. S. Cellular and molecular pathways of extremelylow- frequency electromagnetic d eld in-teractions with living systems. In: Blank, M., ed. Elec-tricity and magnetism in biology and medicine. San Francisco, CA: San Francisco Press; 1993: 1—8.

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