ידיעות כלליות - Nevo.co.il - 04-10-2006.doc · Web viewREHOVOT [74] [57] Apparatus for data processing, said apparatus comprising: a memory (14) operable to store a

142784[21[]11]

סוכנים בשימוש רב–מימדי רשת ניהולמפוזרים עצמאיים

LARGE-SCALE NETWORK MANAGEMENT USING DISTRIBUTED AUTONOMOUS AGENTS

[54]

24.04.2001[22]US[33]28.04.2000[32]60/200507[31]US03.08.200060/222729US30.10.2000698272

Int. Cl.8 H04L 012/24, 012/56, H04Q 003/00[51]SHEER NETWORKS INC., U.S.A.[71]

עו"פ, בע"מ עמיתים אלפאפטנטשמש , בית2345 , ת.ד. 55 רח' ראובן

ALPHAPATENT LTD,,. 55 REUVEN STREET

P.O.BOX 2345BET-SHEMESH 99544

[74]

]57[ A network management architecture for a computer network comprising a plurality of network elements, the network management architecture comprising: a plurality of agents, each of said agents corresponding to a different one of said network elements; and a plurality of device components, each of said device components modeling at least one aspect of one of said network elements, said aspect being either of a physical and a functional characteristic of said network element, wherein each of said agents comprises a plurality of said device components, and wherein at least two of said device components within at least one

of said agents are logically interconnected, each logical interconnection corresponding to either of a physical and a functional interconnection among any of said network elements and said network elements characteristics, characterized in that any of said device components is operative to send a message regarding an event within its area of responsibility to any other of said device components neighboring said device component, whereupon any of said message-receiving device components is operative, responsive to said message receipt, to autonomously change the state of its corresponding area of functionality within its associated network element.

October 5, 20062764 – התשס"ז בתשרי י"ג

__________

142803[21[]11]

PHARMACEUTICAL–טופיסופםR המכילים רוקחות תכשיריCOMPOSITIONS CONTAINING R-TOFISOPAM

[54]

27.10.1999[22]US[33]27.10.1998[32]60/105803[31]

Int. Cl.8 A61K 031/551, A61P 025/22, C07D 243/10[51]VELA PHARMACEUTICALS, INC., U.S.A.

[71]

WO/2000/024400[87]וגולר, וולף, ברגמן

,1352ב' , ת.ד. 19 היסוד קרן רחוב ירושלים

WOLFF, BREGMAN AND GOLLER, 19B KEREN HAYESOD ST .

P.O.B. 1352,JERUSALEM 91013

[74]

]57[ A pharmaceutical composition which comprises an effective amount of R-tofisopam or a pharmaceutically acceptable salt thereof; substantially free of its (S) enantiomer, together with one or

more pharmaceutical carrier(s), diluent(s) and/or additives. The composition is for use in the treatment of anxiety and anxiety disorders.

__________

October 5, 2006 – התשס"ז בתשרי י"ג 2765

142966[21[]11]

FLEXIBLE CONDUITגמישים צינורות מחברCONNECTOR

[54]

04.05.2001[22]Int. Cl.8 F16L 037/00, 041/00[51]

,NAAN IRRIGATIONבע"מ חקלאית שיתופית השקייה-אגודה נעןAGRICULTURAL COOPERATIVE SOCIETY LTD.

[71]

ושות',, ט. קולב סנפורד ,2273, ת.ד. , מרמורק4 הגיא שער

רחובות

SANFORD T.COLB & CO,. P.O.B. 2273 ,

REHOVOT

[74]

]57[ A flexible conduit connector comprising: a hollow, elongate base member (104) defining an outwardly disposed inner facing pheripheral tooth (106) adjacent at least a first end (108) thereof and a generally tapered portion (122) inwardly of said peripheral tooth and characterized in that a cross sectional dimension of the tapered portion decreases with increased distance from said peripheral tooth; and a slidable inner facing generally peripheral tooth arranged for slidable movement in engagement with said generally tapered portion, wherein said outwardly disposed peripheral tooth is

arranged for liquid sealing engagement with a flexible conduit, and said slidable inner facing generally peripheral tooth is arranged for retaining engagement with said flexible conduit and is operative to present an increasing cross section as said slidable inner facing tooth moves along said generally tapered portion towards said outwardly disposed peripheral tooth in response to application of a tension force on said flexible conduit relative to said base member, thereby tightening the engagement between said slidable inner facing generally peripheral tooth and said flexible conduit.

__________


143423[21[]11]

METHOD FOR CONTROLLINGצמחים מזיקי להדברת שיטהPLANT PESTS

[54]

27.01.1999[22]Int. Cl.8 A01N 043/40, 047/40, C07D 213/60[51]SUMITOMO CHEMICAL COMPANY, LIMITED, JAPAN

[71]

WO/2000/044228[87]ושותפיו, עו"פ, הס יצחק ד"ר

אביב , תל6451 , ת.ד. 279 הירקון רחוב DR. YITZHAK HESS & PARTNERS,

279 HAYARKON STREET P.O.B. 6451

TEL AVIV 61063

[74]

]57[ A method for controlling pests harmful to plants which comprises applying an effective amount of (E)-N1-

](6-chloro-3-pyridyl) methyl[-N2-cyano-N1-methylacetamidine and pyriproxyfen to the plants or the surroundings of the plants.

__________

143425[21[]11]

מנתונים ולסינון לקבלה ושיטה נייד ציודמוגדר מיקום בסיס על בתוכנית נלווים

MOBILE APPARATUS AND METHOD FOR RECEIVING AND FILTERING FROM PROGRAM-ACCOMPANYING DATA ON THE BASIS OF A DEFINED POSITION

[54]

02.12.1998[22]Int. Cl.8 G01C 021/20, G01S 005/14, H04H 001/00, H04N 007/088[51]SWISSCOM MOBILE AG, SWITZERLAND

[71]

WO/2000/033493[87]ושות',, ט. קולב סנפורד

,2273, ת.ד. , מרמורק4 הגיא שער רחובות


REHOVOT

[74]

]57[ Portable mobile device (3), which includes a radio receiver (38), by means of which radio programs with program-accompanying digital data are receivable, at least certain of the received program-accompanying data containing location parameters, and which mobile device includes a position locating module (39) for determining the current geographic

position of the mobile device, characterized in that it includes a filter module (37), connected to the radio receiver and to the position locating module, by means of which, on the basis of a current geographic position determined by the said position locating module, location-specific information are


filterable from the said at least certain received program-accompanying data.

__________

143556[21[]11]

INSECTIDICAL SEED COATING[54]חרקים קוטל זרעים ציפוי

14.12.1998[22]Int. Cl.8 A01N 025/10[51]SYNGENTA PARTICIPATIONS AG, SWITZERLAND

[71]

WO/2000/035277[87]לוצאטו, את לוצאטו

שבע , באר5352, ת.ד. תעשיה, עומר גן LUZZATTO & LUZZATTO,

P.O.B 5352BEER-SHEVA 84965

[74]

]57[ An insecticidal coating for a seed comprising:(a) one or more binders, selected from the group consisting of polymers and copolymers of vinyl acetate, vinyl alcohol, vinylidene chloride, acrylic, polyvinylpyrrolidone, cellulose, methyl cellulose and other polysaccharides;(b) an insecticidally effective amount of an insecticide, selected from the group

consisting of imidacloprid, an imidacloprid analog, an organophosphate, a phenylpyrazole, a pyrethroid and a combination thereof; and(c) one or more fillers, wherein the binders form a matrix for the insecticide and the fillers and are present in an amount effective to prevent or reduce the phytotoxic effect on the seed caused by the insecticide.

__________


143595[21[]11]

METHOD FOR EXECUTING Aמאובטחת קריטית פעולת לביצוע שיטהSECURITY CRITICAL ACTIVITY

[54]

17.12.1999[22]SE[33]18.12.1998[32]9804421-7[31]

Int. Cl.8 G06F 012/14[51]MYSPACE AB, SWEDEN[71]WO/2000/038072[87]

ושותפיו, כהן ריינהולד , תל4060 , ת.ד. 21 העם אחד רחוב

אביב

REINHOLD COHN AND PARTNERS,

21 AHAD HA'AM ST ,.P.O.BOX 4060 ,

TEL AVIV 61040

[74]

]57[ A method for executing on a computer a security critical activity having at least one action, the security critical activity being initiated by a user of the computer and executed by a security device connected to the computer, the method comprising the steps of: before starting execution of the security critical activity, the user of the computer defining in a proxy letter a situation in which the proxy letter is allowed to handle the security critical activity; starting execution of an action of the security critical activity in a present situation; determining, for the started action and the present situation and

based on the proxy letter, whether (a) the proxy letter is allowed to handle the started action without direct user involvement or (b) the user is required to handle the started action; when the started action is handled by the proxy letter or by the user, completing the started action and repeating the starting execution and determining steps for each action in the security critical activity until each action in the security critical activity has been completed; andwhen started action is handled neither by the proxy letter nor by the user, stopping execution of the security critical activity.


__________

143634[21[]11]

טלמיסרטן, שיטה של פולימורפיםתרופה בהכנת בהם ושימוש לייצרם

TELMISARTAN POLYMORPHS, METHODS FOR PRODUCING SAME AND THEIR USE IN THE PREPARATION OF A MEDICAMENT

[54]

07.01.2000[22]DE[33]19.01.1999[32]19901921.

5[31]

Int. Cl.8 A61K 031/4184, A61P 009/10, C07D 235/00, 235/20[51]BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG, GERMANY

[71]

WO/2000/043370[87]ושותפיו, כהן ריינהולד

, תל4060 , ת.ד. 21 העם אחד רחוב אביב



TEL AVIV 61040

[74]

]57[ Polymorphic crystal modification B (form B) of telmisartan of the formula


characterisded by an endothermic maximum at 183 ± 2oC which occurs during thermal analysis using DSC.

__________

143637[21[]11]

חומר שלIN VITRO לזיהוי שיטה החומר סימון הכוללת בדוגמא מטרה

גן לביטוי הדרוש והרצף רפורטר גן עםIN VITRO זה רפורטר

METHOD FOR DETECTING IN VITRO A TARGET SUBSTANCE IN A SAMPLE COMPRISING THE LABELLING OF SAID SUBSTANCE WITH A REPORTER GENE AND THE SEQUENCES REQUIRED FOR EXPRESSING SAID REPORTER GENE IN VITRO

[54]

08.12.1999[22]FR[33]08.12.1998[32]98/15489[31]

Int. Cl.8 C12Q 001/68[51]PROTEUS (S.A.), FRANCE[71]WO/2000/034513[87]

צדק, וכהן איתן, פרל, לצר, הרצליה12688 , ת.ד. 7 שנקר רחוב

EITAN, PEARL, LATZER AND COHEN ZEDEK,

P.O.B. 12688 ,HERZLIYA 46733

[74]

[57 ]A method for detecting a target substance in a sample, characterized in that it comprises the following steps:

)a (specific marking of said substance by a reporter gene and by the sequences required for expressing said reporter gene in vitro,

)b (in vitro transcription and translation in an acellular system of said reporter gene, it

being understood that when the target substance is a target nucleic acid sequence, the transcription and translation of said reporter gene does not lead to a reporter protein fused with a protein coded by said target nucleic acid sequence,

)c (in vitro detection of the reporter protein coded by said reporter gene.


__________

143728[21[]11]

ULTRAPHOBIC SURFACE[54]אולטרפובי משטח

22.12.1999[22]DE[33]24.12.1998[32]19860141.

7[31]

DE24.12.199819860136.0DE24.12.199819860134.4

Int. Cl.8 C09K 003/18[51]SUNYX SURFACE NANOTECHNOLOGIES GMBH, GERMANY

[71]





TEL AVIV 61040

[74]

[57 ]A structured surface with ultraphobic properties, characterized in that it has a

surface topography in which the value of the integral of a function S

S(log f)= a (f).f

which indicates a relationship between the spatial frequencies f of the individual Fourier components and the amplitudes a(f) thereof, is at least 0.5 between the integration limits log (f1/µm-1) = -3 and log

(f2/μm-1) = 3, and consists of a hydrophobic or in particular oleophobic material or is coated with a hydrophobic or in particular oleophobic material.

__________


144058[21[]11]

וביצי פירות, ירקות לציפוי תכשיר לתוצרת במיוחד עופות, השימושי

אורגנית

COMPOSITION FOR COATING FRUITS, VEGETABLES AND FOWL EGGS, ESPECIALLY USEFUL FOR ORGANIC PRODUCE

[54]

28.06.2001[22]Int. Cl.8 A01N 003/00, A23B 007/154[51]

NATRATEC INTERNATIONALבע"מ, קצרין בינלאומי נטרטקLTD,.

[71]

YAAKOV LAHAV, EMILוולדמן פוליאנסקי, דניאל להב, אמיל יעקבPOLYANSKY, DANIEL WALDMAN

[72]

ושותפיו, כהן ריינהולד ,4060 , ת.ד. 21 העם אחד רחוב

תל-אביב


21 AHAD HAAM STREET P.O.B. 4060

TEL AVIV 61040

[74]

[57 ]A composition for coating fruits, vegetables, fowl eggs, and especially for organically-grown produce, useful for protection and extension of the shelf life of said fruits, vegetables and fowl eggs, wherein said composition is an aqueous dispersion comprised of:

)a (a hydrophobic component comprising at least one member of the following group consisting of natural wax, or vegetable oil;

)b (an alkali agent;)c (water;

)d (an additive selected from rosemary extract, sage extract, green tea water, eucalyptus oil, lavender oil, citrus peel oil, ethanol, chamomile ethanolic extract, cypress ethanolic extract, prickly pear ethanolic extract, or aloe ethanolic extract; wherein components (a), (b) and (d) are derived from natural biological sources.

__________


144199[21[]11]

וקיטים חדשים ברטיליום תכשירי וטיפול במניעה שלהם והשימושקרדיו–וסקולריים במצבים

BRETYLIUM COMPOSITIONS AND KITS AND THEIR USE IN PREVENTING AND TREATING CARDIOVASCULAR CONDITIONS

[54]

06.01.2000[22]US[33]08.01.1999[32]60/115143[31]US21.01.199960/116567

Int. Cl.8 A61K 031/138, 031/14, 047/12, 047/20, A61P 009/00, C07C 211/00, 211/29[51]MARVIN B. BACANER, U.S.A.MAURICE M. KREEVOY, U.S.A.

[71]

WO/2000/040232[87]צדק, וכהן איתן, פרל, לצר

, הרצליה12688 , ת.ד. 7 שנקר רחוב EITAN, PEARL, LATZER AND COHEN ZEDEK,

P.O.B. 12688 ,HERZLIYA 46733

[74]

[57 ]A pharmaceutical combination useful for preventing and/or treating a cardiovascular condition, said pharmaceutical combination comprising: a bretylium cation or a source of a bretylium cation, a facilitating anion or a source of a facilitating anion, and an anti-hypotensive agent and/or a β-receptor blocker or a source of an anti-hypotensive agent and/or a β-receptor blocker, wherein: said facilitating anion is less hydrophilic than a

tosylate anion; and said bretylium cation or said source of a bretylium cation, said facilitating anion or said source of a facilitating anion, and said anti-hypotensive agent and/or said β-receptor blocker or said source of an anti-hypotensive agent and/or a β-receptor blocker together are present in said pharmaceutical combination in a therapeutically effective amount.

__________

144229[21[]11]

–ציאנואימינו(N)–2 של תולדות–און4תיאזולידין–

2(-N-CYANOIMINO) THIAZOLIDIN-4-ONE DERIVATIVES

[54]

12.11.1999[22]WO[33]12.11.1999[32]PCT/JP99/06352[31]

Int. Cl.8 A61K 031/426, 031/427, A61P 003/06, C07D 277/00, 277/20, 417/12[51]October 5, 20062774 – התשס"ז בתשרי י"ג

FUJIMOTO CO., LTD., JAPAN[71]WO/2001/036402[87]



P.O.B. 12688 ,HERZLIYA 46733

[74]

[57 ]2)-N-cyaniomino (thiazolidin-4-one derivatives or pharmaceutically acceptable salts or solvates thereof of the formula

wherein ring A represents a benzene ring, a condensed ring or a heterocyclic ring, each of which may be substituted by one or more substituents selected from a straight or branched C1-C4 alkyl group, a haloalkyl group, a halogen atom or –OR5;

R1 represents a single bond, an oxygen atom, a sulfur atom, a methyne group, a straight or branched C1-C4 alkylene or alkenylene group optionally substituted by a phenyl group, R6-X, X-R6, X-R6-X, R6-

X-R6, -C(=O)-NR7 – or –NR7-C(=O);-R2 and R3 are the same or different and each represents a hydrogen atom, a C1-C4 alkyl group, -OR8 or a halogen atom;

R4 represents a hydrogen atom or a C1-C4 alkyl group;

R5 represents a hydrogen atom or a C1-C4

alkyl group;R6 represents a straight or branched C1-C4

alkylene or alkenylene group;R7 represents a hydrogen atom or a C1-C4

alkyl group;R8 represents a hydrogen atom, a C1-C4

alkyl group or an aralkyl group;X represents an oxygen atom or a sulfur atom.

__________

144260[21[]11]

נקודתי רב וגרוי עורקית חישהעורקית תזוזה ליצירת כהתערבות

ATRIAL SENSING AND MULTIPLE SITE STIMULATION AS INTERVENTION FOR ATRIAL FIBRILLATION

[54]

11.01.2000[22]US[33]11.01.1999[32]228262[31]

Int. Cl.8 A61N 001/37[51]THE MOWER FAMILY CHF TREATMENT IRREVOCABLE TRUST, U.S.A.

[71]

MORTON M. MOWER[72]October 5, 2006 – התשס"ז בתשרי י"ג 2775

WO/2000/041765[87]ושות' בע"מ, מ. בן-דוד ירמיהו

, ירושלים45087, ת.ד. חוצבים הר JEREMY M. BEN-DAVID & CO.

LTD,. HAR HOTZVIM HI-TECH PARK ,

P.O. BOX 45087 ,JERUSALEM 91450

[74]

[57 ]An implantable cardiac stimulator to perform atrial defibrillation, the cardiac stimulator comprising: sensor (802) adapted to sense the onset of atrial fibrillation; recorder (804) adapted to a record a baseline of cardiac activity; processor adapted to determining whether capture has occurred; and electrodes (808) adapted to stimulate the atrium after the onset of artiral fibrillation has been sensed, wherein, in the event it is determined that capture has not occurred, the atrium is stimulated using a pre-capture stimulation

protocol, wherein, in the event it is determined that capture has occurred, the atrium is stimulated using a post-capture stimulation protocol, and wherein the pre-capture stimulation protocol and the post-capture stimulation protocol comprise a procedure, the procedure being selected from the group consisting of: pre-capture stimulation at threshold with post-capture stimulation at threshold, pre-capture stimulation subthreshold with post-capture stimulation subthreshold, and pre-capture stimulation at threshold with post-capture stimulation subthreshold.

__________


144293[21[]11]

של בהיתוך פולימר של סינתזהפוספין אתר פולי של אוקסידים

MELT POLYMER SYNTHESIS OF POLY ETHER PHOSPHINE OXIDES

[54]

23.12.1999[22]US[33]18.02.1999[32]252296[31]

Int. Cl.8 C08G 065/40, G02B 001/04[51]VIRGINIA TECH INTELLECTUAL PROPERTIES, INC., U.S.A.

JOHNSON & JOHNSON VISION PRODUCTS, INC., U.S.A.

[71]




REHOVOT

[74]

[57 ]A method for producing a poly ether phosphine oxide, said method comprising melt polymerizing reactants comprising

)i (a trimethyl silyl derivative of a bisphenol and (ii) an activated aromatic dihalide, wherein (i), (ii), or (i) and (ii) is a phosphine oxide.

__________

144544[21[]11]

של אזאוטרופ דמוית תרכובות3,3,1,1,1פנטאפלואורובוטן–

AZEOTROPE-LIKE COMPOSITIONS OF 1,1,1,3,3,-PENTAFLUOROBUTANE

[54]

22.03.2000[22]US[33]22.03.1999[32]60/125511[31]US21.03.2000528962

Int. Cl.8 C09K 005/04, C11D 007/50[51]E.I. DUPONT DE NEMOURS AND COMPANY, U.S.A.

[71]




REHOVOT

[74]


[57 ]An azeotrope-like 1, 1, 1,3, 3-pentafluorobutane-containing composition, wherein said composition is selected from the group consisting of:

)i (compositions consisting essentially of from about 1 to about 99 weight percent 1,1,1,2,3,4,4,5,5,5-decafluoropentane and from about 1 to about 99 weight percent 1,1,1,3,3-pentafluorobutane, wherein said composition has a vapor pressure of from about 58.6 kPa to about 100.9 kPa at a temperature of about 40oC;

)ii (compositions consisting essentially of from about 1 to about 95 weight percent 1,1,1,2,3,4,4,5,5,5-decafluropentane, from about 1 to about 98 weight percent 1,1,1,3,3-pentafluorobutane and from about 1 to about 15 weight percent of methanol, wherein said composition has a vapor pressure of from about 72.9 kPa to about 113.2 kPa at a temperature of about 40oC;

)iii (compositions consisting essentially of from about 1 to 95 weight percent 1,1,1,2,3,4,4,5,5,5-decafluoropentane, from about 1 to about 98 weight percent 1,1,1,3,3-pentafluorobutane and from about 1 to about 15 weight percent ethanol, wherein said composition has a vapor pressure of from about 72.7 kPa to about 105.5 kPa at a temperature of about 40oC;

)iv (compositions consisting essentially of from about 1 to about 95 weight percent 1,1,1,2,3,4,4,5,5,5-decafluoropentane, from about 1 to about 98 weight percent 1,1,1,3,3-pentafluorobutane and from about 1 to about 15 weight percent isopropanol, wherein said composition has a vapor pressure of from about 61.8 kPa to about 103.2 kPa at a temperature of about 40oC;

)v (compositions consisting essentially of from about 1 to about 70 weight percent 1,1,1,2,3,4,4,5,5,5-decafluoropentane, from about 28 to about 98 weight percent 1,1,1,3,3-pentafluorobutane and from about 1 to about 10 weight percent acetone, wherein said composition has a

vapor pressure of from about 73.8 kPa to about 100.3 kPa at a temperature of about 40oC;

)vi (compositions consisting essentially of from about 1 to about 80 weight percent 1,1,1,2,3,4,4,5,5,5-decafluoropentane, from about 1 to about 98 weight percent 1,1,1,3,3-pentafluorobutane and from about 1 to about 66 weight percent trans-1,2-dichloroethylene, wherein said composition has a vapor pressure of from about 102.8 kPa to about 118.8 kPa at a temperature of about 40oC;

)vii (compositions consisting essentially of from about 1 to about 60 weight percent 1,1,1,2,3,4,4,5,5,5-decafluoropentane, from about 10 to about 97 weight percent 1,1,1,3,3-pentafluorobutane, from about 1 to about 50 weight percent trans-1,2-dichloroethylene and from about 1 to about 10 weight percent of methanol, wherein said composition has a vapor pressure from about 116.0 kPa to about 128.2 kPa at a temperature of about 40oC;

)viii (compositions consisting essentially of from about 1 to about 60 weight percent 1,1,1,2,3,4,4,5,5,5-decafluoropentane, from about 10 to aobut 97 weight percent 1,1,1,3,3-pentafluorobutane, from about 1 to about 40 weight percent trans-1,2-dichloroethylene and from about 1 to about 10 weight percent ethanol, wherein said composition has a vapor pressure of from about 107.1 kPa to about 118.5 kPa at a temperature of aobut 40oC;

)ix (compositions consisting essentially of from about 1 to about 60 weight percent 1,1,1,2,3,4,4,5,5,5-decafluoropentane, from about 10 to about 97 weight percent 1,1,13,3-pentafluorobutane, from about 1 to about 50 weight percent trans-1,2-dichloroethylene and from about 1 to about 10 weight percent isopropanol, wherein said composition has a vapor pressure of from about 104.9 kPa to about 114.9 kPa at a temperature of about 40oC;

)x (compositions consisting essentially of from about 1 to about 80 weight percent


1,1,1,2,3,4,4,5,5,5-decafluoropentane, from about 1 to about 98 weight percent 1,1,1,3,3-pentafluorobutane and from about 1 to about 49 weight percent n-propyl bromide, wherein said composition has a vapor pressure of from about 70.9 kPa to about 106.5 kPa at a temperature of about 40oC;

)xi (compositions consisting essentially of from about 1 to about 70 weight percent 1,1,1,2,3,4,4,5,5,5-decafluoropentane, from about 10 to about 97 weight percent 1,1,1,3,3-pentafluorobutane, from about 1 to about 35 weight percent n-propyl bromide, and from abut 1 to about 10 weight percent of methanol, wherein said composition has a vapor pressure of from about 89.9 kPa to about 117.0 kPa at a temperature of about 40oC;

)xii (compositions consisting essentially of from about 1 to about 70 weight percent 1,1,1,2,3,4,4,5,5,5-decafluropentane, from about 10 to about 97 weight percent 1,1,1,3,3-pentafluorobutane, from about 1 to about 35 weight percent n-propyl bromide, and from about 1 to about 10 weight percent ethanol, wherein said composition has vapor pressure of from about 85.8 kPa to about 108,3 kPa at a temperature of about 40oC;

)xiii (compositions consisting essentially of from about 1 to about 70 weight percent 1,1,1,2,3,4,4,5,5,5-decafluoropentane, from about 10 to about 97 weight percent 1,1,1,3,3-pentafluorobutane, from about 1 to about 35 weight percent n-propyl bromide, and from about 1 to about 10 weight percent isopropanol, wherein said composition has a vapor pressure of from about 78.7 kPa to about 105.1 kPa at a temperature of about 40oC;

)xiv (compositions consisting essentially of from about 1 to about 67 and from about 92 to about 99 weight percent nonafluoromethoxybutane and from about 33 to about 99 and from about 1 to about 8 weight percent 1,1,1,3,3-pentafluorobutane, wherein said

composition has a vapor pressure of from about 50.1 kPa to about 100.9 kPa at a temperature of about 40oC;

)xv (compositions consisting essentially of from about 1 to about 90 weight percent nonafluoromethoxybutane, from about 1 to about 98 weight percent 1,1,1,3,3-pentafluorobutane and from about 1 to about 15 weight percent of methanol, wherein said composition has a vapor pressure of from about 77.9 kPa to about 113.2 kPa at a temperature of about 40oC;

)xvi (compositions consisting essentially of from about 1 to about 60 weight percent nonafluoromethoxybutane, from about 39 to about 98 weight percent 1,1,1,3,3-pentafluorobutane and from about 1 to about 10 weight percent ethanol, wherein said composition has a vapor pressure of from about 82.7 kPa to about 105.3 kPa at a temperature of about 40oC;

)xvii (compositions consisting essentially of from about 1 to about 60 weight percent nonafluoromethoxybutane, from about 39 to about 98 weight percent 1,1,1,3,3-pentafluorobutane and from about 1 to about 10 weight percent isopropanol, wherein said composition has a vapor pressure of from about 82.1 kPa to aobut 103.1 kPa at a temperature of about 40oC;

)xviii (compositions consisting essentially of from about 1 to about 98 weight percent nonafluoromethoxybutane, from about 1 to about 98 weight percent 1,1,1,3,3-pentaflurobutane and from about 1 to about 98 weight percent acetone, wherein said composition has a vapor pressure of from about 52.1 kPa to aobut 100.3 kPa at a temperature of about 40oC;

)xix (compositions consisting essentially of from about 1 to about 75 weight percent nonafluoromethoxybutane, from about 1 to about 98 weight percent 1,1,1,3,3-pentafluorobutane and from about 1 to about 64 weight percent trans-1,2-dichloroethylene, wherein said composition has a vapor pressure of from


about 93.4 kPa to about 118.7 kPa at a temperature of about 40oC;

)xx (compositions consisting essentially of from about 1 to about 60 weight percent nonafluoromethoxybutane, from about 20 to about 97 weight percent 1,1,1,3,3-pentafluorobutane, from about 1 to about 50 weight percent trans-1,2-dichlorothylene and from about 1 to about 10 weight percent of methanol, wherein said composition has a vapor pressure of from about 113.1 kPa to about 127.8 kPa at a temperature of about 40oC;

)xxi (compositions consisting essentially of from about 1 to about 50 weight percent nonafluoromethoxybutane, from about 20 to about 97 weight percent 1,1,1,3,3-pentafluorobutane, from about 1 about 50 weight percent trans-1,2-dichloroethylene and from about 1 to about 10 weight percent ethanol, wherein said composition has a vapor pressure of from about 104.9 kPa to about 114.8 kPa at a temperature of about 40oC;

(xxi) compositions consisting essentially of from about 1 to about 50 weight percent nonafluoromethoxybutane, from about 20 to about 97 weight percent 1,1,1,3,3-pentafluorobutane, from about 1 to about 35 weight percent trans-1,2-

dichloroethylene and from about 1 to about 9 weight percent isopropanol, wherein said composition has a vapor pressure of from about 103.8 kPa to about 113.6 kPa at a temperature of about 40oC;(xxiii) compositions consisting essentially of from about 1 to about 50 weight percent nonafluoromethoxybutane, from about 30 to about 98 weight percent 1,1,1,3,3-pentafluorobutane and from about 1 to about 49 weight percent n-propyl bromide, wherein said composition has a vapor pressure of from about 90.7 kPa to about 106.6 kPa at a temperature of about 40oC; and(xxiv) compositions consisting essentially of from about 1 about 70 weight percent nonafluoromethoxybutane, from about 10 to about 97 weight percent 1,1,1,3,3-pentafluorobutane, from about 1 to about 35 weight percent n-propyl bromide and from about 1 to about 10 weight percent of methanol, wherein said composition has a vapor pressure of from about 93.4 kPa to about 118.0 kPa at a temperature of about 40oC, and wherein after 50 weight percent of said composition has evaporated the vapor pressure of the remaining composition has changed by about 10 percent or less.

__________


144646[21[]11]

תוך–כלי–דמי, שיטות ארוגים התקניםלהעברתם ותקן לעשייתם

WOVEN INTRAVASCULAR DEVICES AND METHODS FOR MAKING THE SAME AND APPARATUS FOR DELIVERY OF THE SAME

[54]

01.02.2000[22]US[33]01.02.1999[32]60/118211[31]US18.03.199960/125191

Int. Cl.8 A61F 002/06[51]BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, U.S.A.

[71]





TEL AVIV 61040

[74]

]57[ A device comprising: a plurality of shape memory wires (5) woven together to form a body (10) suitable for implantation into an anatomical structure, the body having first and second ends (2, 12) the shape memory wires crossing each other to form a plurality of angles, at least one of

the angles being obtuse, and both ends of at least one shape memory wire being located proximate one end of the body; wherein the value of the least one obtuse angle may be increased by axially compressing the body.


__________

144698[21[]11]

SLOT-DRILLING CUTTER[54]חריצי גזירה מקדח

02.08.2001[22]DE[33]01.09.2000[32]10043016.

3[31]

Int. Cl.8 B23B 051/04, B23C 005/10[51]WALTER AG, GERMANY[71]

ושותפיו, עו"פ, הס יצחק ד"ראביב , תל6451 , ת.ד. 279 הירקון רחוב

DR. YITZHAK HESS & PARTNERS, 279 HAYARKON STREET

P.O.B. 6451 TEL AVIV 61063

[74]

]57[ Drilling groove cutter (1) with a tool body (2), which has at least a first tip seat (5) and at least a second tip seat (6), which are identical in configuration and are arranged symmetrically to a rotational axis (25) of the tool body, with a first cutting tip (3) and with a second cutting tip (4), which are identical in configuration and respectively have a base face, side faces and an upper side (3a, 4a), which define a substantially straight front cutting edge (7, 8), a corner cutting edge (9, 11) and a substantially straight peripheral cutting edge (12, 14), wherein the front cutting edges, the corner cutting edges and the

peripheral cutting edges are positioned identically in axial direction (a) and in radial direction (r), wherein either(a) the front cutting edges of the two cutting tips extend at least as far as a centre of rotation, which surrounds the rotational axis and is defined by inner cutting edges (41, 42), or (b) an inner cutting tip (23) adjoins at least one of the cutting tips without any gap, its cutting edge extending at least as far as the centre of rotation surrounding the rotational axis, wherein the upper sides of the cutting tips are staggered substantially parallel to one an-other.


__________

144699[21[]11]

לחיתוך צלחת סידור עם ממתכת תגזירישיר

METAL CUTTING WITH DIRECT CUTTING PLATE ARRANGEMENT

[54]

02.08.2001[22]DE[33]01.09.2000[32]10043015.

5[31]

Int. Cl.8 B23C 005/10, 005/22[51]WALTER AG, GERMANY[71]

ושותפיו, עו"פ, הס יצחק ד"ראביב , תל6451 , ת.ד. 279 הירקון רחוב


P.O.B. 6451 TEL AVIV 61063

[74]

]57[ A metal cutting tool (1), in particular for milling work, having a tool body (2), in which at least two adjoining plate seats (7, 8) for cutting plates (14, 15) are formed, each of which respectively has a base (18, 28), an end face (17, 27) and lateral faces

(20, 32) extending between the base and the end face, wherein the plate seats are arranged in such a way that the cutting plates touch each other, at least over areas, with their lateral faces when the cutting plates are fastened on their plate seats.


__________

144704[21[]11]

RECEPTACLE WITH INWARDLYפנימה בולטים ומכסה שפה בעל מיכלPROJECTING RIM AND LID

[54]

02.02.2000[22]GB[33]02.02.1999[32]9902244.4[31]

Int. Cl.8 B65D 043/06[51]PCC TECHNOLOGIES PLC, UNITED KINGDOM

[71]





[74]

]57[ A plastics container comprising a receptacle and lid, the receptacle having a rim (2) projecting inwardly from adjacent walling and the lid being a press fit into the

rim, wherein the rim of the receptacle has an upstanding first flange (21) forming the inner limb of a first upwardly-open channel (22) between whose outer limb


and the walling of the receptacle laterally extends a second flange (24) and the periphery of the lid has an inner depending skirt (10) that closely co-operates with the inside of the first flange, an undulating portion outward of the skirt forming two open channels, namely a downwardly-open channel (14) which receives the first flange and a second upwardly-open channel (16) which seats sealingly within the first upwardly-open channel, and an outer flange (18) that overlies the second flange,

characterized in that the inner and outer sides of the first upwardly-open channel flow from the base of the channel respectively inwardly and outwardly of the receptacle so that the second upwardly-open channel, whose underside is of complementary shape, wedges therein to provide a sealing function, while a projection (11) at the base of the skirt has snap engagement under the first upwardly-open channel as sealing is effected to provide a retaining function.

__________

144742[21[]11]

WATER DISPERSIBLEבמים המתפרקת הגיינית תחבושתPANTILINER

[54]

31.03.2000[22]US[33]03.04.1999[32]285595[31]

Int. Cl.8 A61F 013/15[51]KIMBERLY-CLARK WORLDWIDE, [71]


INC, U.S.A.WO/2000/059427[87]


אביב



TEL AVIV 61040

[74]

]57[ A water dispersible pantiliner consisting essentially of: a peel strip (1) comprising a paper base sheet coated with a polyvinyl alcohol binder and silicone release agent, and; a water soluble garment attachment adhesive (2) which adhesively attaches said peel strip to a first side of a baflle (3), said garment attachment adhesive present in an amount between 10 and 60 gsm, and; said baffle comprising a blend of polyethylene oxide and ethylene co-acrylic acid in an amount of about

between about 20/80 and 95/5 weight percent, and; a construction adhesive (4) which adhesively attaches said baffle to an absorbent core (5) which is in turn attached to a body side liner, said construction adhesive present in an effective amount, and; said absorbent core comprising pulp and water dispersible polymer fibers in a range to about 5/95 to 95/5 weight percent, and; said body side liner comprising crimped water dispersible sheath core conjugate fibers.

__________

144907[21[]11]

בשימוש תלת–מימדית רקונסטרוקציהעל–קול

THREE-DIMENSIONAL RECONSTRUCTION USING ULTRASOUND

[54]

14.08.2001[22]US[33]18.08.2000[32]60/226708[31]US10.07.2001902087

Int. Cl.8 A61B 008/00[51]BIOSENSE, INC., U.S.A.[71]

ושות', כהן שלמה ד"ראביב , תל11490 , ת.ד. 124 גבירול אבן

DR. SHLOMO COHEN & CO,,. 124 IBN GABIROL ST ,

P.O.B. 11490 ,TEL AVIV 62038

[74]


]57[ Apparatus for mapping a surface of a cavity within a body of a subject (26), comprising: an elongate probe (30), having a longitudinal axis and comprising a distal portion adapted for insertion into the heart (24) and a probe position sensor, which is adapted to generate signals indicative of position coordinates of the probe within the body; a plurality of acoustic transducers, distributed along the longitudinal axis over the distal portion of the probe, which transducers are adapted to be actuated individually to emit acoustic waves while the probe is in the heart, and are further adapted to receive the acoustic waves after reflection of the waves from the surface of the heart and to generate, responsive to the received waves, electrical signals indicative of times of flight of the

waves; a reference position sensor maintained in a fixed position relative to the body of the subject; signal processing circuitry for receiving the electrical signal indicative of times of flight of the waves from the acoustic transducers and for receiving the signals indicative of position

coordinates of the probe from the probe position sensor for reconstructing a three-dimensional geometric map of the surface of the heart, the signal processing circuitry also comparing the signals indicative of position corrdinates of the probe to the fixed position of the reference position sensor for determining a position of the probe position sensor which accounts for motion of the heart.

__________

144913[21[]11]

לחלוקת מפלסית דו תקשורת מערכת בלולאה הספקה בקרת בעלת זמן

פתוחה

WEIGHTED OPEN LOOP POWER CONTROL IN A TIME DIVISION DUPLEX COMMUNICATION SYSTEM

[54]

22.03.2000[22]US[33]22.03.1999[32]60/125417[31]US28.05.199960/136556US28.05.199960/136557

Int. Cl.8 H04B 007/005[51]INTERDIGITAL TECHNOLOGY CORPORATION, U.S.A.

[71]






TEL AVIV 61040

[74]

]57[ A method for controlling transmission power levels in a spread spectrum time division duplex communication system having frames with time slots for communication, the method comprising: transmitting a first communication having a transmission

power level in a first time slot from a first communication station; receiving at a second communication station the first communication and measuring a power level of the first communication as received; determining a path loss estimate based on in part the measured received

first communication level and the first communication transmission power level; setting a transmission power level for a second communication in a second time slot from the second station to the first station based on in part combining the path loss estimate weighted by a first factor with a long term path loss estimate weighted by a second factor, wherein the first and second factors are a function of a time separation of the first and second time slots; and determining a quality, α, of the pathloss estimate based on in part a number of time slots, D, between the first and second time slot; and wherein the first factor is α and the second factor is 1-α.

__________

145023[21[]11]

צינור עבור הגנה המבטיח התקןהעיכול במערכת המוחדר

SECURING DEVICE FOR A LOW PROFILE GASTROSTOMY TUBE

[54]

24.02.2000[22]US[33]24.02.1999[32]257164[31]

Int. Cl.8 A61M 025/04, 031/00[51]


SHERWOOD SERVICES AG, SWITZERLAND

[71]





TEL AVIV 61040

[74]

]57[ A device (10) designed to pass through an opening in the wall of the abdomen and stomach or other viscera of a patient, said device comprising: a feed set (14), said feeding set including an elongated tube having one end attached to a source of fluid and another end attached to a connection member; a feeding tube including a tubular member (16) disposed inside the opening of a patient and

interposed between an external retention member (18) seated on the outside of a patient and an internal retention member anchored inside the viscera of a patient, said connection member being attachable

to said external retention member for establishing fluid flow communication between said source of fluid and a patient; and a securing member (12) having opposed portions and being slidably engaged along said elongated tube, one of said opposed portions securely engaging said connection member and the other of said opposed portions securely engaging said external retention member, whereby said connection member cannot be disengaged from said external retention member without first detaching one of said opposing portions of said securing device from either said connection member or said external retention member.

__________


145083[21[]11]

של התפוקה להגברת ושיטה מערכתרדיו ברשת מידע העברת

SYSTEM AND METHOD OF INCREASING THE MESSAGE THROUGHPUT IN A RADIO NETWORK

[54]

23.08.2001[22]US[33]13.09.2000[32]661403[31]

Int. Cl.8 H04L 012/28, 012/56, 012/58, 029/06[51]HARRIS CORPORATION, U.S.A.[71]


אביב



TEL AVIV 61040

[74]

]57[ A method of increasing the message throughput in a radio network comprising the steps:(a) providing a message queue of message packets ranked in desired order of transmission at a source radio, each packet having a destination radio associated therewith;(b) providing a radio queue of destination radios associated with the message packets in the message queue ranked in order as a function of the ranking of the messages in the message queue;(c) monitoring all other radios in the radio network at a source radio to determine the

availability of each radio to receive a transmission;(d) selecting the highest ranked available destination radio from the radio address queue;(e) selecting the messages in the message queue corresponding to the selected destination radio; and(f) transmitting the selected messages, whereby to allow a message packet ranked lower in the message queue to be transmitted before a message packet ranked higher in the message queue if the destination station associated with the higher ranked message is unavailable.


__________

145131[21[]11]

לשיפור ושיטות ביולוגים תכשירים צמחים וייצור צמחים ובריאות גדילתמחלות מדכאי

BIOLOGICAL COMPOSITIONS AND METHODS FOR ENHANCING PLANT GROWTH AND HEALTH AND PRODUCING DISEASE-SUPPRESSIVE PLANTS

[54]

29.02.2000[22]US[33]01.03.1999[32]60/122311[31]US18.06.199960/139850US23.02.2000511359

Int. Cl.8 A01N 063/00, C12N 001/20[51]UNIROYAL CHEMICAL COMPANY, INC., U.S.A.AUBURN UNIVERSITY, U.S.A.

[71]




REHOVOT

[74]

]57[ A composition for enhancing plant growth and/or imparting disease resistance which comprises at least two plant growth-promoting rhizobacteria (PGPR) strains and a chitinous component chosen among chitin, flaked chitin, chitosan and

precursors thereof in a range from 0.1% to 10%, wherein at least one of the PGPR is selected from the genera Bacillus, Paenibacillus, Brevibacillus, Virgibacillus, Alicyclobacillus, and Aneurinibacillus.


__________

145166[21[]11]

המשמשות ביפניל תולדות1נאורוקינין– קולטן של כאנטגוניסטים

BIPHENYL DERIVATIVES AS ANTAGONISTS OF THE NEUROKININE-1 RECEPTOR

[54]

28.02.2000[22]EP[33]09.03.1999[32]99104626.

9[31]

Int. Cl.8 A61K 031/166, C07C 217/54, 233/15, 233/44, 233/66, 235/42, C07D 233/00, 295/14

[51]

F. HOFFMANN-LA ROCHE AG, SWITZERLAND

[71]





TEL AVIV 61040

[74]

]57[ Compounds of the formula:

whereinR is hydrogen, (C1-C7)-alkyl, (C1-C7)-alkoxy, halogen, amino, -N(R6)2 or trifluoromethyl;R1 is hydrogen, (C1-C7) – alkoxy or halogen;R and R1 may be together –CH=CH-CH=CH-;R2 is halogen, (C1-C7) – alkyl or trifluoromethyl;R3 is hydrogen or (C1-C7)-alkyl;R4 is hydrogen or a cyclic tertiary amine, optionally substituted by (C1-C7)-alkyl;R5 is hydrogen, nitro, amino or –N(R6)2;

R6 is hydrogen or (C1-C7)-alkyl;X is –C(O)N(R6)-, -(CH2)nO-, -(CH2)nN(R6)-, -N(R6)C(O)- or N(R6)(CH2)n-;andn is 1 or 2;and pharmaceutically acceptable acid addition salts thereof; with the exclusion of the compound ]1, 1'-biphenyl[-2-methanamine, N-](4-methylphenyl) methyl[- and of the compound ]1,1'-biphenyl[-2-methanamine, N-]]4-(1,1-dimethylethyl) phenyl[ methyl[-N-methyl-, hydrochloride.


__________

145292[21[]11]

מתח גבוהת ממוחשבת טומוגרפיהרדיותרפיה במהלך

MEGAVOLTAGE COMPUTED TOMOGRAPHY DURING RADIOTHERAPY

[54]

29.03.2000[22]US[33]02.04.1999[32]60/127630[31]

Int. Cl.7 A61N 005/10[51]WISCONSIN ALUMNI RESEARCH FOUNDATION, U.S.A.

[71]





TEL AVIV 61040

[74]

[57 ]A combination radiation therapy and tomographic imaging machine (10) comprising: a megavoltage radiation source directing a radiation beam (26) formed of rays directed generally along an axis; a gantry (12) holding the radiation source to rotate the angle of the axis about a treatment volume; a radiation detector (28) positioned on the gantry across the treatment volume opposite the radiation source to receive and measure radiation of the rays to provide data of a projection; a modulator modulating the flux of the rays passing through the treatment volume; an electronic computer (22) executing a stored program to:

)i (control the modulator to direct selected high flux rays at selected axis angles at the

patient within the treatment volume according to a radiation treatment plan, the selected rays and angles comprising less than a tomographic projection set, to acquire a high flux incomplete tomographic projection set from the radiation detector;

)ii (direct low flux rays at the patient within the treatment volume to acquire low flux data from the radiation detector;

)iii (combine the high flux incomplete tomographic projection set and the low flux data to produce an augmented complete tomographic projection set; and

)iv (reconstruct a tomographic image of the patient from the augmented complete tomographic projection set.


__________

145327[21[]11]

פינים ניצרות עם גלילי נעילה מנגנוןמסתובבות

CYLINDER LOCK WITH ROTATABLE PINS

[54]

07.03.2000[22]US[33]08.03.1999[32]263852[31]

Int. Cl.8 E05B 019/06, 027/06[51]MOSHE DOLEV[71]השרון דולב, רמת משהAMIR ZIV-AV[72]זיו-אב אמיר

WO/2000/053870[87]לנגר, אדוארד

אביב , תל44-46מונטיפיורי EDWARD LANGER,

44-46 MONTEFIORE STREETTEL AVIV 65201

[74]

[57 ]A locking system comprising a cylinder lock of a type having rotatable pins which must be rotated to a given rotational position to effect unlocking thereof, and a key (32) for use therewith, said cylinder lock comprising:

)a (a cylinder housing defining a bore;)b (a plug deployed within said bore, said

plug having a longitudinal axis and defining a keyway and at least one pin channel communicating with said keyway; and

)c (at least one pin (44) disposed in said at least one pin channel so as to be displaceable along, and rotatable about, a pin axis, said pin having an engagement end proximal to said keyway, wherein said engagement end is formed with at least two engagement features projecting parallel to, but displaced from, said pin

axis, said at least two engagement features being separated by at least one depression, and wherein said pin is free to rotate through 360 degrees about said pin axis, said engagement features being terminated in rounded end portions, said key comprising: a key shaft (34) configured for insertion into said cylinder lock along said keyway in a direction of insertion, said key shaft having at least one pin-engaging face (36) which features a plurality of recessed seats (38), each of said plurality of recessed seats being configured to rotate said at least one pin to any given rotational position relative to said direction of insertion, wherein each of said plurality of recessed seats is formed with at least two similar conical depressions (40) intersecting along a line so as to form an intermediate ridge (42), said intermediate


ridge being capable of contact with said engagement features only at a contact point which subtends a relatively very small angle with respect to said pin axis, such that at said contact point, any resting

position of said engagement features on said ridge is unstable, causing said engagement features to slide into proper engagement within said conical depressions.

__________

145447[21[]11]

אדנווירוסים לשימור תכשירמדבקים רקומביננטים

COMPOSITION FOR THE PRESERVATION OF INFECTIOUS RECOMBINANT ADENOVIRUSES

[54]

07.04.2000[22]FR[33]09.04.1999[32]99/04443[31]US30.04.199960/132120

Int. Cl.8 C12N 007/00[51]AVENTIS PHARMA S.A., FRANCE[71]WO/2000/061726[87]

לוצאטו, את לוצאטושבע , באר5352, ת.ד. תעשיה, עומר גן

LUZZATTO & LUZZATTO, P.O.B 5352

BEER-SHEVA 84965

[74]

[57 ]A composition comprising adenoviral particles, a buffer solution that maintains the pH of said composition between 8.0 and 9.6, and glycerol, wherein

said buffer solution does not contain added divalent metal cations or alkali metal cations.

__________


145521[21[]11]

קישור אמצעי עם פיטמטית זרבוביתחלוקה למכשיר

TEAT NOZZLE FOR DOSING DEVICE WITH CONNECTION MEANS

[54]

17.03.2000[22]GB[33]27.03.1999[32]99070146.

6[31]

Int. Cl.8 A61J 007/00, 011/04, 015/00[51]SMITHKLINE BEECHAM BIOLOGICALS S.A., BELGIUM

[71]





TEL AVIV 61040

[74]

[57 ]A teat nozzle (1) suitable for peadiatric oral dosing of a fluid medicament comprising a tubular conduit (2) having an internal channel (3) along which a fluid medicament may be caused to flow toward a nozzle opening (4) of the conduit, the conduit being engageable in a male-female co-operation with a female socket, wherein the conduit is provided externally with at least one engagement

part which can engage with an internal helical screw thread in such a female socket, to thereby facilitate connection between the conduit and the socket, and wherein said engagement part comprises two substantially hemispherical or rounded conical bumps (5) regularly circumferentially disposed 180o apart around the circumference of the outer surface of the conduit.


__________

145566[21[]11]

ANTIMICROBIAL POLYMERICחיידקים קוטלי פולימריים תכשיריםCOMPOSITIONS

[54]

16.02.2000[22]Int. Cl.8 A01N 035/02, C08F 016/34, C08L 029/00[51]CHEMEQ LTD., AUSTRALIA[71]WO/2001/060874[87]

ושותפיו, כהן ריינהולדאביב , תל4060 , ת.ד. 21 העם אחד רחוב



TEL AVIV 61040

[74]

[57 ]A method for improving the antimicrobial activity of a polymer derived from acrolein monomer wherein the polymer has been oxidized in air to form an oxidized acrolein polymer comprising carboxyl groups, said method comprising: providing a solution of the oxidized acrolein polymer comprising carboxyl

groups in a mixture containing water and a solvent comprising an alcohol selected from the group consisting of polyols, polyethylene glycols and alkanols; and heating the solution at a temperature in the range of from 40 to 150oC or a period sufficient to improve the antimicrobial activity of the acrolein polymer.

__________

145616[21[]11]


VAGINAL SPECULUM WITHחותמת עם וגינלי מפסקSEAL

[54]

30.03.2000[22]AU[33]28.04.1999[32]PQ0034[31]AU07.05.1999PQ0233

Int. Cl.7 A61B 001/303[51]S.S.H. MEDICAL LIMITED, AUSTRALIA

[71]

WO/2000/064329[87]ושותפיו, עו"פ, הס יצחק ד"ר

אביב , תל6451 , ת.ד. 279 הירקון רחוב DR. YITZHAK HESS & PARTNERS,

279 HAYARKON STREET P.O.B. 6451

TEL AVIV 61063

[74]

[57 ]A vaginal speculum of the kind including a tubular probe (6) for penetrating the vagina characterized in that said probe is encircled by an annular

sealing element spaced from the leading end of the probe which seals only against a circumferential zone of the internal tissue defining the vaginal orifice and is shaped

as a surface of revolution wherein the diameter of the sealing surface increases progressively with axial distance from the leading end of the sealing element and wherein the rate of increase diminishes progressively with said axial distance.

__________

145651[21[]11]

מטמון זיכרון עבור ( מצבBITS) סיביות(CACHE)

STATUS BITS FOR CACHE MEMORY

[54]

04.02.2000[22]GB[33]08.06.1999[32]9913348.0[31]

Int. Cl.8 G06F 012/08, G11C 015/00[51]ARM LIMITED, UNITED KINGDOM[71]WO/2000/075785[87]


ושות',, ט. קולב סנפורד ,2273, ת.ד. , מרמורק4 הגיא שער

רחובות


REHOVOT

[74]

[57 ]Apparatus for data processing, said apparatus comprising: a memory (14) operable to store a plurality of data words, each data word being associated with at least one status bit (18) giving information regarding a status of said data word; a status bit store (26, 28) operable to store said status bits within a hierarchical relationship such that a combined status relating to a plurality of first level status bits at a first level within said hierarchical relationship is indicated by a second level status bit (22) at a second level within said hierarchical relationship, said second level being higher in said hierarchical relationship than said first level; status

querying logic (30) operative to determine a status of a data word within said memory by examining status bits within said status bit store starting at a top level within said hierarchical relationship and working down through said hierarchical relationship until a status bit is reached that indicates said status of said data word independently of any status bits lower in said hierarchical relationship; and characterized in that said apparatus is operable to indicate a global change in status of all data words stored within said memory by modifying only those status bits within a highest level of said hierarchical relationship.


146014[21[]11]

תמונות וחיישן אנלוגי אות לעיבוד מעגלמפורט בזמן

CIRCUIT FOR PROCESSING A TIME-DISCRETE ANALOG SIGNAL AND IMAGE SENSOR

[54]

30.03.2000[22]DE[33]20.04.1999[32]19917863.

1[31]

Int. Cl.8 H03F 003/72, H04N 003/15, 005/335[51]FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V., GERMANY

[71]

WO/2000/064142[87]ושות', גבריאלי זליגסון

אביב , תל1426 , ת.ד. 31 רח' יבנה SELIGSOHN GABRIELI & CO,.

31 YAVNE ST.P.O.B. 1426

TEL AVIV 61013

[74]

[57 ]Circuit for processing an analog signal comprising a time sequence of discrete signal levels, with each discrete signal level lying in a time interval and representing an information-carrying section of the interval, while the remainder of the interval is a non-information carrying section, the circuit comprising: a transistor (10) with a first (10a), a second (10b), and a third (10c) terminal, with the transistor being arranged such that by means of a signal at the first terminal a current flow between the second and the third terminal is controllable, that the time-discrete analog signal (Uc) is adapted to be applied the first terminal, and that the third terminal is adapted to be coupled to an output node (19) of the circuit; a means (14) for applying a voltage between a first node (16) with a first potential (UB; OV)

and a second node (18) with a second potential (O V; UB), with the first node being adapted to be coupled to the second terminal of the transistor; a means (20) for delivering a direct current (IDC) between two terminals, with one terminal being connected to the output node and the other terminal being connected to the second node; a first switch (24), which is normally opened and which is controllable (ф1), in order to connect, in a closed state, the output node, during at least a part of the non-information carrying section of the interval, to a reference node to generate a reference potential at the output node of the circuit; and a second switch, which is connected between the second terminal of the transistor and the first node and which is controllable to interrupt an electrically conductive connection between the first node and the second terminal of the transistor for at least as long as the first switch connects the third terminal of the transistor to the reference node.


__________

146442[21[]11]

שרשרת עם סטרואידיות תרכובות וטבעת –אלקילC17 של צדדית

בריפוי לשימושA ארומטית

STEROID COMPOUNDS WITH A C17-ALKYL SIDE CHAIN AND AN AROMATIC A-RING FOR USE IN THERAPY

[54]

11.05.2000[22]GB[33]11.05.1999[32]9910934.0[31]

Int. Cl.8 A61K 031/575, A61P 003/00, 005/00, 007/00, 009/00, 011/00, 017/00, 019/00, 021/00, 025/00, 029/00, 035/00, 037/00, C07J 009/00, 041/00, 051/00

[51]

RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC., U.S.A.

[71]

WO/2000/068246[87]צדק, וכהן איתן, פרל, לצר

, הרצליה12688 , ת.ד. 7 שנקר רחוב EITAN, PEARL, LATZER AND COHEN ZEDEK,

P.O.B. 12688 ,HERZLIYA 46733

[74]

[57 ]Compounds of the formula


in which: R1 and R2, which may be the same or different, each represents a C1-6 alkyl, C2-7 alkenyl or C2-7 alkynyl group;

R3 represents a methyl group having α- or β-configuration;

R4 represents a hydrogen atom, a C1-6 alkyl group or an etherifying silyl group;

R5 represents a hydrogen atom, a hydroxyl group or a C1-6 alkoxy group;

X represents a group OR4, wherein R4 is as defined above, or a group NR6R7 wherein R6 represents a hydrogen atom, a C1-6 alkyl group, a C6-12 carbocyclic aryl C1-4 alkyl

group, a C1-6 alkanoyl group, a C6-12 carbocyclic aryl C2-5 alkanoyl group or a C7-13 carbocylcic aroyl group; and R7 represents a hydrogen atom or a C1-6 alkyl group;

Y represents an alkylene, alkenylene or alkynylene group containing up to 7 carbon atoms and up to 3 multiple bonds, optionally substituted by a hydroxyl group; and the dotted lines signify that double bonds may be present at the 16(17)-position and/or either at the 6(7)- and 8(9)-positions or at the 7(8)-position.

__________146453[21[]11]

תמונות של אוטומטית להתפלגות שיטהרפואיות

METHOD FOR AUTOMATIC SEGMENTATION OF MEDICAL IMAGES

[54]

12.11.2001[22]US[33]22.11.2000[32]721195[31]

Int. Cl.8 A61B 006/03, G06T 005/00, 017/00[51]GENERAL ELECTRIC COMPANY, U.S.A.

[71]

ושות', גבריאלי זליגסוןאביב , תל1426 , ת.ד. 31 רח' יבנה

SELIGSOHN GABRIELI & CO,. 31 YAVNE ST.

P.O.B. 1426 TEL AVIV 61013

[74]

[57 ]An method for automatically extracting a three-dimensional substructure from a plurality of slice images, said method comprising: depositing a seed point within a selected region of interest on at least one of said slice images; and,

segmenting said plurality of slice images responsive to said deposited seed point and in accordance with a plurality of predetermined classification values to extract said three-dimensional sub-structure, wherein said sub-structure


structure, wherein said sub-structure comprises a coronary vessel tree.

__________

146526[21[]11]

MEDICAL POSITIONINGרפואית מיקום מערכתSYSTEM

[54]

18.05.2000[22]US[33]18.05.1999[32]314474[31]

Int. Cl.8 A61B 005/05[51]MEDIGUIDE LTD.[71]בע"מ, חיפה מדיגייד

WO/2000/069335[87]ושות', אליעזרי קורח בורוכוב

,58100, ת.ד. עתידים כלל מגדל תל-אביב

BOROCHOV, KORAKH, ELIEZRI & CO,

15 TH FLOOR, ATIDIM TOWER, KIRYAT ATIDIM P.O.BOX 58100

TEL AVIV 61580

[74]

[57 ]Apparatus for determining the position and orientation of a surgical tool relative to a reference frame, in association with an image, comprising: a magnetic field transmitter (108), including at least

one magnetic field generating element; a detection probe including at least one magnetic field detector; a signal generation module, connected to said at least one magnetic field generating element; a


detection processor (104), connected to said detection probe; and mounting means, for mounting onto said surgical tool, said signal generation module determining a multiple frequency transmit signal and providing said multiple frequency processor receiving a detected signal from said detection probe, at least a portion of

said detected signal corresponding to said multiple frequency transmitted signal, determining the location and orientation of said detection probe from the power of said at least a portion of said detected signal, and indicating the location of said surgical tool within said image.

__________

146576[21[]11]

NAPHTHALENE UREAS ASגלוקוזה ספיגת כמחישי אוריאה נפתלןGLUCOSE UPTAKE ENHANCERS

[54]

25.05.2000[22]US[33]26.05.1999[32]60/136128[31]

Int. Cl.8 A61K 031/18, 031/395, 031/66, A61P 003/10, C07C 275/28, 309/02, 309/51, 311/08, 311/47, 323/64, C07D 211/96, 213/76, 233/32, 241/20, 257/04, C07F 009/40

[51]

TELIK, INC., U.S.A.[71]WO/2000/071506[87]


אביב



TEL AVIV 61040

[74]

[57 ]Compounds of the formula:


whereR1 and R2 are substituents on the A rings and are, independently, -SO2NR7

2, -C(O)NR7

2, -NR7SO2R7,- NR7C(O)R7, -NR7C(O)R7, -SO2OR7, -

C(O)OR7, -OSO2R7, or –OC(O)R7;R3 and R4 are, independently, hydrogen, or lower alkyl, or R3 and R4 together are –

(CH2)2-, -(CH2)3-, or –(CH2)3 ,-or –(CH2)4;-

R5 and R6 are, independently, hydrogen, alkyl, substituted alkyl, cyano, halo, nitro, -SR8, -C(O)R8, -SO2OR8, -OSO2R8, -SO2NR8

2, -NR8SO2R8, -OC(O)R8, -C(O)OR8, -C(O)NR8

2, -NR8C(O)R8, -OR8, or --NR8

2; each R7 and R8 is,

independently, hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, aryl (lower) alkyl, substituted aryl (lower) alkyl, heteroaryl (lower) alkyl, substituted heteroaryl (lower) alkyl, heterocyclyl, substituted heterocyclyl, substituted heterocyclyl, heteroaryl, or substituted heteroaryl; each Y is, independently, alkyl, substituted alkyl, substituted alkyl, cyano, halo, nitro, -SR, OR, or –NR2, where each R is, independently, hydrogen, lower alkyl, or substituted lower alkyl; each x is, independently, 0, 1 or 2, andlinker connects a carbon designated as c to a carbon designated as d, and is:

and, where, if R1 and R2 are both –SO2OH, then:

)i (neither R5 nor R6 is –SO2OR8 or –OSO2R8; and

)ii (R5 and R6 are not both selected from the group consisting of hydroxyl and hydrogen unless at least one (Y)x is (Y')x' where x' is 1 or 2 and Y' is a halo, or a pharmaceutically acceptable salt thereof,

as a single stereoisomer or mixture of stereoisomers; wherein each of the terms "alkyl", "lower alkyl", "aryl", "heteroaryl", "heterocyclyl", "substituted alkyl", "substituted lower alkyl", "substituted aryl", "substituted heteroaryl" and "substituted heterocyclyl" are as defined in the specification.

__________

146807[21[]11]

של רוקחות תכשירלאוודופה/קרבידופה/אנטאקאפ

ון

LEVODOPA/CARBIDOPA/ENTACAPONE PHARMACEUTICAL PREPARATION

[54]


29.06.2000[22]FI[33]30.06.199

9[32]991485[31]

Int. Cl.8 A61K 045/00[51]ORION CORPORATION, FINLAND[71]WO/2001/001984[87]

ושותפיו, עו"פ, הס יצחק ד"ר ,6451 , ת.ד. 279 הירקון רחוב

אביב תל


P.O.B. 6451 TEL AVIV 61063

[74]

[57 ]An oral solid composition comprising pharmacologically effective amounts of entacapone, levodopa and carbidopa, or pharmaceutically acceptable salts or hydrates thereof, and a pharmaceutically acceptable excipient, wherein a substantial portion of carbidopa is separated from entacapone and levodopa, whereby the therapeutical effect

achieved with the said composition in the treatment of Parkinson's disease is comparable to that achieved with the separate formulations of entacapone and levodopa-carbidopa which are administered concomitantly at the same doses of the active agents as in the said oral solid composition.

__________

146925[21[]11]

–7 – [ פירןb] אוקסובנזו2 – תולדותוהכנתן ליקסופירנוזידa– – L – איל

2 - OXOBENZO [B] PYRAN - 7 - YL - Α - L - LYXOPYRANOSIDE DERIVATIVES AND THEIR PREPARATION

[54]

10.06.1997[22]FR[33]11.06.1996[32]9607207[31]

Int. Cl.8 A61K 031/7048, A61P 031/04, C07H 017/075[51]DIVISION FROM 127133[62]AVENTIS PHARMA S.A., FRANCE[71]WO/1997/047634[87]



P.O.B. 12688 ,HERZLIYA 46733

[74]


[57 ]Compounds of the formula

in which: x

║ Z represents a hydrogen atoms or a C-R1 radical,R1 represents a hydrogen atom, a hydroxyl radical, an alkyl, alkenyl or alkynyl radical

optionally interrupted by an oxygen, sulphur or nitrogen atom, containing up to 12 carbon atoms, linear, branched or cyclic, optionally substituted by one or more halogen atoms, one or more OH ,

Ra ∕

C≡N, NO2, N , radicals, in which Ra and Rb,\

Rb

identical or different, represent a hydrogen atom , an alkyl radical containing up to 8 carbon atoms, or Ra and Rb form with the nitrogen atom to which they are linked a

heterocycle optionally containing another heteroatom chosen from nitrogen, sulphur or oxygen, or R1 represents an alkoxy radical containing up to 8 carbon atoms ,

optionally substituted by one or more of the substituents indicated above, or R1 represents an NRcRd radical in which Rc and Rd, identical or different, represent a

hydrogen atom or an alkyl radical optionally interrupted by an oxygen, sulphur or nitrogen atom, containing up to 12 carbon atoms, optionally substituted by one or more of the substituents indicated above, or Rc and Rd form together with the nitrogen atom to which they are linked a heterocycle optionally containing another heteroatom chosen from nitrogen, sulphur or oxygen, X represents an oxygen atom, or an N-Nalk1 or NOalk2 radical in which alk1 and alk2 represent an alkyl radical optionally interrupted by an oxygen, sulphur or nitrogen atom containing up to 12 carbon atoms optionally substituted by one or more

Re ∕

halogen atoms, by one or more N radicals in which \

Rf


Re and Rf, identical to or different from each other represent a hydrogen atom, an alkyl radical containing up to 8 carbon atoms, optionally substituted, or Re and Rf are able to form together with the nitrogen atom to which they are joined a heterocycle which in addition is able to contain an oxygen, sulphur atom and another nitrogen atom, R2 represents a hydrogen atom or a halogen atom, R3 represents a hydrogen atom, an alkyl radical containing up to 8 carbon atoms or

a halogen atom, R5 represents an O-alkyl radical containing up to 4 carbon atoms, R6

represents an alkyl or CH2-O-alkyl radical, in which alkyl represents an alkyl radical containing up to 8 carbon atoms, R7 represents a hydrogen atom or an alkyl radical containing up to 8 carbon atoms, R8

represents a free or blocked hydroxyl radical, OR'4 represents a blocked hydroxyl radical, R''4 represents a hydrogen atom or R'4 and R''4 form together with the carbon atoms to which they are joined a cycle,

as well as their salts excluding the compounds wherein at the same time Z is

C(X)R1, R8 is OH, R''4 is H and R'4 is C(O)R4.

שטרם זו לבקשה הורה בקשתפורסמה

127133The parent application from which this application has been divided has not yet been published

__________

146926[21[]11]

באפיק הפס רוחב לניהול ושיטה מערכתדו–כיוונית לווינית במערכת חוזר

SYSTEM AND METHOD FOR MANAGING RETURN CHANNEL BANDWIDTH IN A TWO-WAY SATELLITE SYSTEM

[54]

12.04.2001[22]US[33]14.04.2000[32]60/197246[31]US15.02.2001783850

Int. Cl.8 H04B 007/185, 007/212[51]HUGHES ELECTRONICS CORPORATION, U.S.A.

[71]




REHOVOT

[74]


[57 ]A method for managing return channel bandwidth in a two-way satellite communication system, the method comprising: receiving backlog information corresponding to a plurality of transceivers, each of the transceivers being configured to transmit respective backlog information over a return channel via a satellite, the backlog information specifying an amount of queued traffic for the respective transceivers; allocating a predetermined amount of return channel bandwidth to each of the plurality of transceivers; determining whether additional return channel bandwidth is available to accommodate a remaining backlog such that a bandwidth allocation

amount is set based upon a level associated with one of the plurality of transceivers having the largest backlog; selectively identifying a transceiver among the plurality of transceivers having a next largest backlog based upon the determining step; selectively adjusting the bandwidth allocation amount based upon a level associated with the transceiver with the next largest backlog; and allocating the additional return channel bandwidth to the plurality of transceivers based upon the adjusted bandwidth allocation amount if the adjusted bandwidth allocation amount reduces at least a portion of the backlog of the plurality of transceivers.

__________

147076[21[]11]

תכונות עם ביקרבונט אמינוגואנידיןליצורו ושיטה מסוימות

AMINOGUANIDINE BICARBONATE WITH PARTICULAR PROPERTIES AND METHOD FOR MAKING SAME

[54]

08.06.2000[22]FR[33]16.07.1999[32]99/09257[31]

Int. Cl.8 C07C 277/02, 279/02[51]ATOFINA, FRANCE[71]WO/2001/005752[87]


אביב



TEL AVIV 61040

[74]


[57 ]A virtually spherical aggregate of amino guanidine bicarbonate crystals with a mean diameter of between 80 and 500

μm and preferably between 100 and 250 μm.

__________

147374[21[]11]

שגיאה בפני להגנה גמישה שיטהתיקשורות במערכות

FLEXIBLE METHOD OF ERROR PROTECTION IN COMMUNICATIONS SYSTEMS

[54]

19.06.2000[22]US[33]02.07.1999[32]347251[31]

Int. Cl.8 H03M 013/09, H04L 001/00[51]ERICSSON INC., U.S.A.[71]





[74]

[57 ]A method of variable degree error coding, comprising: selecting between a plurality of levels of error protection,each of said error protection levels having a different corresponding generator code; CRC encoding a data message at a first station using the generator code corresponding to the selected error

protection level to produce an encoded message; transmitting said encoded

message from said first station to a second station; at said second station, CRC decoding said encoded message using a first generator code to produce a first result and CRC decoding said encoded message using a second generator code to produce a

second result, and determining, at said second station, the selected error protection level based on said first and second results.


__________

147422[21[]11]

לקישוריות פתרונות לקביעת טכניקהרשת של אלמנטים

TECHNIQUE OF DETERMINING CONNECTIVITY SOLUTIONS FOR NETWORK ELEMENTS

[54]

31.12.2001[22]Int. Cl.8 H04L 012/24, 012/26[51]

ECI TELECOM LTD.[71]תקוה בע"מ, פתח אי.סי.איי. טלקוםבע"מ, אי. סי. איי. טלקום

תקוה , פתח30הסיבים רחוב ECI TELECOM LTD,

30 HASIVIM ST.PETACH TIKVA 49517

[74]

[57 ]A method of finding connectivity solutions for network elements to be switched into a path selected in a network managed by a network management system (NMS), wherein each network element comprises input ports and output ports, each of the ports enabling a plurality of connection points, the method comprising providing, at the level of NMS, a connectivity table (CT) comprising data

on possible internal connections between connection points of any input port and any output port of any of the network elements managed by said NMS, thereby enabling, whenever a particular network element is selected with its input port and its output port to be used in the path, obtaining a connectivity solution for said particular network element at the level of NMS.


__________

147478[21[]11]

SAFETY CATCH FOR PISTOLS[54]נשק לכלי ניצרה

03.01.2002[22]Int. Cl.8 F41A 017/74[51]FABBRICA D'ARMI PIETRO BERETTA S.P.A., ITALY

[71]

פטנטים דין, עורכי עורכי לצר צדק כהן פרלונוטריונים,

, הרצליה12704 , ת.ד. 5שנקר

PEARL COHEN ZEDEK LATZER, 5 SHENKAR STREET ,

P.O.BOX 12704 HERZLIYA 46733

[74]

[57 ]A gun device, comprising: a firing hammer (11) rotating on an axis (12) between a released position and an armed position; a thrust spring (13); said firing hammer rotating against the action of said thrust spring, a spring-holder rod (14), said thrust spring being associated and guided with said spring-holder rod, the spring-holder rod having an end (15) connected eccentrically to said firing hammer and an opposite free end (16) of a noncircular cross section; a safety catch including: a safety body (18) fixable to a part of a stock of said gun device in association with the free end of the spring-holder rod, said safety body defining a housing; a safety

pin (19) mounted in the housing of the safety body in an arrangement that is aligned with the free end of the spring-holder rod and is capable of axial, rotary translatory movements; and a defined contour key (20) for access and coupling to a part (27) of the safety pin for the rotary translatory movements of the safety pin between a passive, lowered position, which does not affect the spring-holder rod for a normal functioning of the gun, and an active, raised position for the longitudinal blocking of the spring-holder rod for blocking the firing hammer in the released position and inhibiting the functioning of the gun.


__________

147686[21[]11]

אוויר מרווח בעל קבוע מגנט מצמדמתכוונן

PERMANENT MAGNET COUPLER WITH ADJUSTABLE AIR GAPS

[54]

04.08.2000[22]US[33]04.08.1999[32]368385[31]

Int. Cl.8 H02K 049/04[51]MAGNA FORCE, INC., U.S.A.[71]





[74]

[57 ]An adjustable magnetic coupler comprising: first and second rotary shafts (17) having a coaxial rotary axis, a cage (10) mounted on said first shaft and surrounding said axis; a magnet rotor (12) mounted on said second shaft and extending radially within said cage from said second shaft, said magnet rotor containing permanent magnets (42); two

electro-conductive units (28, 29) movably carried by said cage and spaced by air gaps (40, 41) from said magnets at opposite ends of the magnet rotor; and gap adjustment means (38) for controlling the axial location of said electro-conductive units axially relative to said cage and magnet rotor to selectively vary said air gaps.


__________

148231[21[]11]

מערכת עבור מבוזר מטמון זיכרוןאל–חוטית תקשורת

DISTRIBUTED CACHE FOR A WIRELESS COMMUNICATION SYSTEM

[54]

01.09.2000[22]US[33]01.09.1999[32]388236[31]

Int. Cl.8 G06F 017/00, 017/30, 019/00[51]NEXTWAVE TELECOM INC., U.S.A.[71]





TEL AVIV 61040

[74]

[57 ]A wireless system comprising: a plurality of base stations (114), each of said plurality of base stations servicing remote units (118, 120, 124) located within a corresponding limited physical coverage area; a central controller (112) coupled to each of said plurality of base stations; a network (100) coupled to said central controller and coupled to each of said plurality of base stations via said central controller, characterized by a cache (116)

associated with a first base station of said plurality of base stations and storing digital data retrieved over said network; wherein when said first base station receives a message from a wireless user requesting a file and said file is stored within said cache said first base station identifies said file from said message, retrieves said file from said cache and forwards said file to said wireless user.


__________

148288[21[]11]

ותולדות אינדולאלקאנול של אסטרים להכנתם אינדולאלקילאמיד, תהליכים

אותם המכילים רוקחות ותכשירי

INDOLEALKANOL ESTER AND INDOLEALKYLAMIDE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

[54]

23.08.2000[22]US[33]30.08.1999[32]385748[31]

Int. Cl.8 A61K 031/4045, 031/405, A61P 029/00, C07D 209/12, 209/14[51]VANDERBILT UNIVERSITY, U.S.A.[71]





[74]

[57 ]A compound of the formula


where:R = C1 to C6 alkyl, C1 to C6 branched alkyl, C4 to C8 cycloalkyl, C1 to C6 hydroxyalkyl, branched C1 to C6 hydroxyalkyl, hydroxy substituted C4 to C8 aryl, primary, secondary, or tertiary C1 to C6 alkylamino, primary, secondary, or tertiary branched C1

to C6 alkylamino, primary, secondary, or tertiary C4 to C8 arylamino, C1 to C6 alkylcarboxylic acid, branched C1 to C6 alkylcarboxylic acid, C1 to C6 alkylester, branched C1 to C6 alkylester, C4 to C8 aryl, C4 to C8 arylcarboxylic acid, C4 to C8 arylester, C4 to C8 aryl substituted C1 to C6

alkyl, C4 to C8 heterocyclic alkyl or aryl with O, N, or S in the ring, alkyl-substituted or aryl-substituted C4 to C8 heterocyclic alkyl or aryl with O, N, or S in the ring, or halosubstituted versions of the aforementioned moieties defining R, where halo is chloro, bromo, fluoro, or

iodo, R1 = C1 to C6 alkyl, C1 to C6 branched alkyl, C4 to C8 cycloalkyl, C4 to C8 aryl, C5 to C8 aryl-substituted C1 to C6 alkyl, C1 to C6 alkoxy, C1 to C6 branched alkoxy, C4 to C8 aryloxy, or halo-substituted versions of the aforementioned moieties defining R1, or R1 is halo, where halo is chloro, fluoro, bromo, or iodo,R2 = hydrogen, C1 to C6 alkyl or C1 to C6

branched alkyl,n = 1, 2, 3, or 4, andwhen R3 = halobenzyl, then X=NH or N-R4, where R4 = C1 to C6 alkyl or C1 to C6

branched alkyl, and when R3 = halobenzoyl, then X = O, and the compound possesses selectivity for inhibition of cyclooxygenase-2, where selectivity is at least 1015 for the ratio of IC50 for cyclooxygenase-1 divided by IC50 for cyclooxygenase-2.


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