1-O-B1-1 Possible Involvement of PACAP-PAC1 Receptor ......Yuki Kurauchi1,2, Risako Tanaka 2, Sumika Ryu, Makito Haruta3, Kiyotaka Sasagawa3, Takahiro Seki 1,2, Jun Ohta3, Hiroshi

1-O-B1-1

Possible Involvement of PACAP-PAC1 Receptor Signaling System to ItchSensation in Mice.

Ichiro Takasaki1, Sho Kato1, Ryuta Ikeda1, Mayuko Murata1, Hiroki Saito2, Yuki Kambe2,Hiroaki Gouda3, Takuya Okada4, Naoki Toyooka4, Atsuro Miyata2, Takashi Kurihara2

1Dept. Pharmacol., Grad. Sch. Sci. Eng., Univ. Toyama,2Dept. Pharmacol., Grad. Sch. Med. Dent., KagoshimaUniv., 3Dept. Analytical and Physical Chem., Sch. Pharmacy., Showa Univ., 4Dept. Bio-func. Mol. Eng., Grad. Sch.Sci. Eng., Univ. Toyama

Oral Sessions

Copyright © The Japanese Pharmacological Society

1-O-B1-2

Role of MrgprA3-expressing primary sensory neurons in itch responses inatopic dermatitis model mice

Masanori Fujii, Kyoko Fujii, Ryosuke Miyagawa, Satoshi Tanaka

Dept. Pharmacol., Kyoto Pharm. Univ.

Oral Sessions


1-O-B1-3

Involvement in serotonin receptor subtypes on spontaneous itch-relatedbehavior in mice with atopy-like dermatitis

Tsugunobu Andoh1,2, Takeshi Osaki2, Daisuke Uta2, Yasushi Kuraishi3, Toshiaki Kume2

1Dept. Pharmacol. Pathophysiol., College Pharm., Kinjo Gakuin Univ., 2Dept. Applied Pharmacol., Sch. Med.Pharm. Sci., Univ. Toyama,3Wakayama Med. Univ.

Oral Sessions


1-O-B1-4

Evaluation of the anti-inflammatory and anti-pruritic responses of fish oil ina mouse model of dermatitis

Fukuyama Tomoki1, Chiharu Hayakawa1, Masaharu Kiyosue2

1Laboratory of Veterinary Pharmacology, School of Veterinary Medicine, Azabu University,2Oriental Yeast Co.,Ltd.

Oral Sessions


1-O-B2-1

Histamine activation of periaqueductal grey matter and somatosensorycortex exerts an antinociceptive effect in mechanical allodynia.

Mei Yu1, Takeo Yoshikawa1, Fumito Naganuma2, Kazuhiko Yanai1

1Dept Pharmacol. Sch Med. Tohoku Univ.,2Div Pharmacol. Fac Med. Tohoku Med and Pharmaceut Univ.

Oral Sessions


1-O-B2-2

A thrombin inhibitor aggravates HMGB1-dependent colonic and bladderpain: Role of the thrombomodulin/thrombin system in visceral painmodulation

Ayumu Yamagata1, Kazuki Matsui1, Maho Tsubota1, Masahiro Nishibori2, Atsufumi Kawabata1

1Lab. Pharmacol. Pathophysiol., Fac. Pharm., Kindai Univ., 2Dept. Pharmacol., Okayama Univ. Grad. Sch. Med.

Oral Sessions


1-O-B2-3

Exacerbation of paclitaxel-induced peripheral neuropathy and HMGB1-induced allodynia in ovariectomized mice

Ayano Kanto1, Shiori Hiramoto1, Maho Tsubota1, Hiroaki Matsunaga1, Tomoyoshi Miyamoto1,2,Yuichi Koizumi2, Masahiro Nishibori3, Atsufumi Kawabata1

1Lab. Pharmacol. Pathophysiol., Fac. Pharm., Kindai Univ., 2Dept. Pharm., Seichokai Fuchu Hospital, 3Dept.Pharmacol., Okayama Univ. Grad. Sch. Med.

Oral Sessions


1-O-B2-4

Sex-dependent suppressive effects of PLX3397, a microglial inhibitor, onnerve injury-induced neuropathic pain in mice

Norikazu Kiguchi1, Kentaro Suzuki2

1Dept. Pharmacol., Sch. Med., Wakayama Med. Univ.,2Dept. Development. Genet., Inst. Adv. Med., WakayamaMed. Univ.

Oral Sessions


1-O-B3-1

Sex-dependent pain-regulatory effects of spinal microglia using Gi / GqDREADD systems in mice

Fumihiro Saika, Norikazu Kiguchi, Shinsuke Matsuzaki, Tomoe Nishitani-Nakamura

Dept. Pharmacol. Wakayama Med Univ.

Oral Sessions


1-O-B3-2

Astrocytic histamine N-methyltransferase controls locomotor activity andvigilance state

Rina Otsuka1, Fumito Naganuma2, Yuki Sato1, Yuna Takahashi1, Kazuhiko Yanai1,Takeo Yoshikawa1

1Dept. Pharmacol., Grad. Sch. Med., Tohoku Univ.,2Div. Pharmacol., Fac. Med., Tohoku Med. Pharmaceut. Univ.

Oral Sessions


1-O-B3-3

Astrocytic mGluR5 controls microglial phagocytosis in the critical period,which fates a lifelong cortical circuits

Yosuke Danjo1, Youichi Shinozaki1,2, Parajuli Bijay1,2, Ken-Ichi Dewa3, Yuto Kubota1,Takahiro Segawa4, Eiji Shigetomi1,2, Koizumi Schuichi1,2

1Dept Neuropharmacol, Interdiscip Grad Sch Med, Univ Yamanashi,,2Yamanashi Interdiscipinary Brain-ImmuneResearch Center,, 3Dept Biochem and Cell Biol, Natl Inst Neurosci, NCNP,,4Cent Life Sci Res., Univ. Yamanashi,

Oral Sessions


1-O-B3-4

Positive effect of microglia repopulation on the Alexander diseasepathology, the primary astrocyte disease

Kenji Kobayashi1, Eiji Shigetomi1, Bijay Parajuli1, Yuto Kubota1, Kozo Saito1, Kenji Tanaka2,Kazuhiro Ikenaka3, Schuichi Koizumi1

1Dept Neuropharmacol, Interdiscipl Grad Sch Med, Univ Yamanashi,2Dept Neuropsych, Keio Univ Sch Med., 3DivNeurobiol and Bioinfo, NIPS

Oral Sessions


1-O-B3-5

Implication of glutamine-glutamate metabolic change in astrocyte viacGAMP transmitted by metastatic cancer cells

Hiromi Sato1, Toya Okawa1, Kurumi Hara1, Kyoko Goto1, Moe Kikuchi1, Hiroki Tanaka2,Daiki Shirane2, Takuma Yamakawa2, Hidetaka Akita2, Hiroto Hatakeyama1, Akihiro Hisaka1

1Clinical Pharmacology & Pharmacometrics, Grad. Sch. Pharmaceut. Sci., Chiba Univ., 2Design and DrugDisposition, Grad. Sch. Pharmaceut. Sci., Chiba Univ.

Oral Sessions


1-O-C1-1

Establishment of meteoropathy model mice

Yuki Kurauchi1,2, Risako Tanaka2, Sumika Ryu2, Makito Haruta3, Kiyotaka Sasagawa3,Takahiro Seki1,2, Jun Ohta3, Hiroshi Katsuki1,2

1Dept Chemico-Pharmcol Sci, Grad Sch Pharm Sci, Kumamoto Univ, 2Dept Chemico-Pharmacol Sci, Sch Pharm,Kumamoto Univ, 3Division of Materials Science, Graduate School of Science and Technology, Nara Institute ofScience and Technology

Oral Sessions


1-O-C1-2

Protective effects of protein SUMOylation on BBB permeability intherapeutic hypothermia for ischemic brain injury

Tanaka Yuta, Mayuko Monden, Masatomo Watanabe, Yutaka Tamura

Dept. Pharmacol., Fac. Pharm. & Pharmaceut. Sci., Fukuyama Univ.

Oral Sessions


1-O-C1-3

Roles of DNA methylation in neuronal cell death after ischemic injury

Mayumi Asada1, Hideki Hayashi1, Kenjiro Murakami1, Kento Kikuiri1, Ryotaro Kaneko1, Bo Yuan2,Norio Takagi1

1Dept. Appl. Biochem., Sch. Pharm., Tokyo Univ. Pharm. and Life Sci.,2Lab. Pharmacol., Fac. Pharm. andPharmaceut. Sci., Sch. Pharm., Josai Univ.

Oral Sessions


1-O-C1-4

The efficacy and safety of a laser thrombolytic system in an animalthrombosis model

Yuji Matsumoto1, Daisuke Yamashita2, Yoshiyuki Shimizu2, Yohei Takata2, Tsuyoshi Kosugi2,Yoshinori Tamaoki2, Hiroyuki Okada2, Teiji Nakayama3, Kazuo Umemura1

1Dep. Pharmacol., Hamamatsu Univ. Sch. Med., 2Hamamatsu Photonics K.K., 3Dep. Neurosurg., HamamatsuMedical Center

Oral Sessions


1-O-C2-1

Prenatal hypoxic stress caused the decrease of astrocytes in theneurodevelopmental disorder-related region of rat brain

Kentaro Tokudome1, Masaaki Ueki1,2, Takehiro Yamaguchi1, Shinji Matsunaga1, Shuhei Tomita1

1Dept. Pharmacol., Grad. Sch. Med., Osaka City Univ., 2Dep. Anesthesiol., Nishiwaki Municipal Hospital

Oral Sessions


1-O-C2-2

Effect of voluntary exercise after cerebral ischemia on functional recoveryand the peri-infarct cortex

Natsumi Yamaguchi1, Kae Fukumoto1, Toshinori Sawano1, Jin Nakatani1, Daijiro Yanagisawa2,Ikuo Tooyama2, Hidekazu Tanaka1

1Lab. Pharmacol., Grad. Sch. Life Sci., Ritsumeikan Univ., 2Dept. Diag. and Therap. for Brain Dis., Mol. Neurosci.Res. Ctr., Shiga Univ. Med. Sci.

Oral Sessions


1-O-C2-3

Function of novel Iba1-positive cells appearing in the ischemic core

Toshinori Sawano1, Natsumi Yamaguchi1, Jin Nakatani1, Shinobu Inagaki2,3,Takayuki Nakagomi4, Tomohiro Matsuyama4, Hidekazu Tanaka1

1Lab. Pharmacol., Grad. Sch. Life Sci., Ritsumeikan Univ., 2United Grad. Sch. Child Develop., Osaka Univ., 3Dept.PT., Yukioka Col. Health Sci.,4Lab. Neurogenesis and CNS Repair., Inst. Adv. Med. Sci., Hyogo Col. Med.

Oral Sessions


1-O-C2-4

Amthamine, a selective histamine H2 receptor agonist alleviatescerebrovascular damage after traumatic brain injury in mice

Shotaro Michinaga, Kyomi Sonoda, Naoki Inazuki, Tomokazu Watano, Hiroyuki Mizuguchi

Dept. pharmacol. Osaka-ohtani Univ.

Oral Sessions


1-O-C3-1

Effects of high fat diet feeding and lipopolysaccharide treatment onneuroinflammation, neurogenesis, or cognitive function in mice

Toshiaki Ishizuka1, Wataru Nagata1, Sayaka Takahashi1, Hiroyuki Ohta1, Yasushi Satoh2

1Dept. Pharmacol., Natl. Def. Med. Coll., 2Dept. Biochem., Natl. Def. Med. Coll.

Oral Sessions


1-O-C3-2

Recovery of memory deficits by the overexpression of Shati/Nat8l in thehippocampus in a mouse model of Alzheimer’s disease

Chino Kakeru1, Naotaka Izuo1, Tomoharu Kuboyama2, Chihiro Tohda2, Shinichi Muramatsu3,4,Atsumi Nitta1

1Dept of Pharmaceutical and Neuropharmcol Therap, Fact of Pharmaceutical Sci, Grad Univ of Medical andPharm Sci, Univ of Toyama, 2Sect of Neuromedical Sci, Div of Biosci, Inst of Nat Med, Univ of Toyama, 3Div ofNeuro Gene Thera, Open Innov Ctr, Univ of Jichi Med, 4Ctr of Gene & Cell Thera, Ins of Med Sci, Univ of Tokyo

Oral Sessions


1-O-C3-3

Coffee polyphenols prevent cognitive decline and suppress amyloid βplaques in APP/PS2 transgenic mouse

Keiko Ishida, Masaki Yamamoto, Kensuke Misawa, Hitomi Nishimura, Koichi Misawa,Naoki Yamamoto, Noriyasu Ota

Kao Corporation Biological Science Research

Oral Sessions


1-O-C3-4

Coffee polyphenols ameliorate cognitive decline via maintenance of blood-brain barrier (BBB) integrity in senescence-accelerated mouse prone 8(SAMP8)

Nishimura Hitomi, Masaki Yamamoto, Keiko Ishida, Tomoya Hirata, Naoki Yamamoto,Kouichi Misawa, Takatoshi Murase, Noriyasu Ota


Oral Sessions


1-O-C3-5

Chlorogenic acid (5-caffeoylquinic acid) suppresses cognitive decline byfacilitating Aβ clearance in APP/PS2 transgenic mice

Keiko Ishida, Masaki Yamamoto, Hitomi Nishimura, Tomoya Hirata, Koichi Misawa,Naoki Yamamoto, Noriyasu Ota


Oral Sessions


1-O-D1-1

Activation of YAP is essential for the myocardial recovery from myocarditis

Shoki Fukuyama1, Yusuke Kametani1, Yuriko Wada1, Shota Suzuki1, Ayaka Umeda1,Makiko Maeda2, Shota Tanaka1, Masanori Obana1, Yasushi Fujio1

1Laboratory of Clinical Science and Biomedicine., Grad. Sch. Pharm., Osaka Univ., 2Laboratory of ClinicalPharmacology and Therapeutics., Grad. Sch. Pharm., Osaka Univ.

Oral Sessions


1-O-D1-2

Cardioprotective roles of novel cell death inhibitor, defender against celldeath 1 (Dad1)

Shota Mori1, Shota Tanaka1, Makiko Maeda2, Masanori Obana1, Yasushi Fujio1,2

1Laboratory of Clinical Science and Biomedicine, Grad. Sch. Pharm., Osaka Univ., 2Laboratory of ClinicalPharmacology and Therapeutics, Grad. Sch. Pharm., Osaka Univ.

Oral Sessions


1-O-D1-3

Regulation of fibrosis inhibitory factors by NOX1/NADPH oxidase in H9c2cardiomyocytes

Kazumi Iwata, Chihiro Yabe-Nishimura

Dept. Pharmacol., Kyoto Pref. Univ. Med.

Oral Sessions


1-O-D1-4

2,5-Dimethylcelecoxib attenuates cardiac remodeling after cryoinjury-induced myocardial infarction by suppressing the fibroblast-myofibroblasttransformation

Ikushima Eigo1, Shin Ishikane1, Takehiro Kishigami1, Hiroaki Matsunaga1, Tomohiro Takiguchi2,Yumiko Toyohira1, Fumi Takahashi-Yanaga1

1Department of Pharmacology, School of Medicine, University of Occupational and Environmental Health, Japan.,2Department of Clinical Pharmacology, Graduate School of Medical Sciences, Kyushu University

Oral Sessions


1-O-D2-1

Molecular mechanisms of Doxorubicin-induced cardiomyopathy,involvement in the impairment of mitophagy

Takeya Sato1, Mikio Muraoka1, Noriko Toda1,2, Guanjie Li1, Masanori Yamauchi2, Masaki Saito1,Teruyuki Yanagisawa1

1Dept. Mol. Pharm. Tohoku Univ. Grad.Sch. Med.,2Dept. Anesthesiol. Perioperat. Med. Tohoku Univ. Grad.Sch.Med

Oral Sessions


1-O-D2-2

Induction of Autophagy Attenuates Imatinib-induced Cardiotoxicity

Miyuki Kobara, Hiroe Toba, Tetsuo Nakata

Department of Clinical Pharmacology, Kyoto Pharmaceutical University

Oral Sessions


1-O-D2-3

Oncocardiology of Anticancer Molecular Target Drugs

Kayoko Yamada1,2, Kyoko Yamamoto1,2, Yuka Mizutani1,2, Noriko Ichino1,2, Aoi Mori1,2,Yukiko Kato1,2, Yasuhito Shimada3, Yuhei Nishimura3, Toshio Tanaka1,2

1Department of Systems Pharmacology Mie University Graduate School of Medicine, 2Mie University MedicalZebrafish Research Center,3Department of Integrative Pharmacology Mie University Graduate School of Medicine

Oral Sessions


1-O-D2-4

Cancer cachexia-induced myocardial impairment could be improved byvoluntary wheel running

Miki Nonaka1, Susumu Ueno2, Ryo Kakigi3, Nagomi Kurebayashi4, Takashi Murayama4,Kanako Miyano5, Kiyoshi Terawaki6, Takashi Sakurai4, Yasuhito Uezono1

1Dept. Pain Control Res., Jikei Univ. Sch. Med., 2Dept. Occup. Toxicol., Inst. Ind. Ecol. Sci., Univ. Occup. Environ.Hlth., 3Fac. Management & Information Sci, Josai International University, 4Dept. Pharmacol., Juntendo Univ. Sch.Med., 5Div. Pathophysiol., Natl. Cancer Ctr. Res. Inst.,6Tsumura Res. Labo., Tsumura & Co.

Oral Sessions


1-O-D3-1

Effects of RyR2 specific inhibitors on arrhythmia in CPVT model mice

Nagomi Kurebayashi1, Takashi Murayama1, Koichiro Ishii1, Masato Konishi1, Masami Sugihara2,Shuichi Mori3, Hiroto Iinuma3, Mari Ishigami-Yuasa3, Nobuyuki Murakoshi4, Hiroyuki Kagechika3,Takashi Sakurai1

1Dept Cell Mol Pharmacol, Juntendo Univ Grad Sch Med, 2Dept Clin Lab Med, Juntendo Univ Gad Sch Med, 3IBB,Tokyo Med Dent Univ,4Dept Cardiol, Fac Med, Univ Tsukuba

Oral Sessions


1-O-D3-2

Cardiac safety pharmacological characteristics of class Id antiarrhythmicdrug ranolazine in the halothane-anesthetized dog

Yoshio Nunoi1,2, Ryuichi Kambayashi1, Ai Goto1, Yoshiki Hirokawa1, Hiroko Izumi-Nakaseko1,Mihoko Hagiwara-Nagasawa1, Yoshinori Takei3, Akio Matsumoto4, Shinichi Kawai5,Yoshinori Watanabe2, Atsushi Sugiyama1,3,4,5

1Dept. Pharmacol., Faculty Med., Toho Univ.,2Div. Cardiovasc. Surg., Dept. Surg., Faculty Med, Toho Univ.,3Dept.Translational Research & Cellular Therapeutics, Faculty Med., Toho Univ.,4Dept. Aging Pharmacol., FacultyMed., Toho Univ.,5Dept. Inflammation & Pain Control Research, Faculty Med., Toho Univ.

Oral Sessions


1-O-D3-3

Analysis of onset mechanisms on clinically reported, lamotrigine-inducedcardiovascular adverse events as a reverse translational research using thehalothane-anesthetized dogs

Ai Goto1, Yoshiki Hirokawa1, Yoshio Nunoi2, Ryuichi Kambayashi2, Hiroko Izumi-Nakaseko1,2,Mihoko Hagiwara-Nagasawa2, Akio Matsumoto3, Yoshinori Takei4, Shinichi Kawai5,Atsushi Sugiyama1,2,3,4,5

1Dept. Pharmacol., Grad. Sch. Med., Toho Univ.,2Dept. Pharmacol., Faculty. Med., Toho Univ.,3Dept. AgingPharmacol., Faculty. Med., Toho Univ.,4Dept. Translational Research & Cellular Therapeutics., Faculty. Med.,Toho Univ.,5Dept. Inflammation & Pain Control Research, Faculty. Med., Toho Univ.

Oral Sessions


1-O-D3-4

Electropharmacological effects of licorice decoction on the heart: integralassessment using in vitro and in vivo models

Hiroko Izumi-Nakaseko1, Koki Chiba2, Ai Goto1, Ryuichi Kambayashi1, Yoshio Nunoi1,Mihoko Hagiwara-Nagasawa1, Akio Matsumoto3, Yoshinori Takei4, Shinichi Kawai5,Atsushi Sugiyama1,3,4,5

1Dept. Pharmacol., Faculty. Med., Toho Univ.,2Dept. Trad. Med., Faculty Med., Toho Univ.,3Dept. TranslationalResearch & Cellular Therapeutics, Faculty Med., Toho Univ.,4Dept. Aging Pharmacol., Faculty Med., Toho Univ.,5Dept. Inflammation & Pain Control Research, Faculty Med., Toho Univ.

Oral Sessions


1-O-D3-5

Nardilysin controls heart rate through the transcriptional regulation of ionchannels critical for sinus automaticity.

Mikiko Ohno1, Hiroshi Matsuura2, Takeru Makiyama3, Yasuhiko Koujitani3, Kiyoto Nishi3,Hirotaka Iwasaki1, Shintaro Matsuda3, Takeshi Kimura3, Eiichiro Nishi1

1Dept. Pharm. Shiga Univ. Med. Sci., 2Dept. Phisio. Shiga Univ. Med. Sci., 3Dept. Cardiovasc. Med, Grad. Sch.Med., Kyoto Univ.

Oral Sessions


1-O-G1-1

Generation of a transgenic zebrafish line suitable for in vivo imaging ofapoptosis in liver

Aina Higuchi1, Eri Wakai1, Yuka Adachi1, Tomoko Tada2, Junko Koiwa1, Takashi Shiromizu1,Toshio Tanaka3, Yuhei Nishimura1

1Dept. Integrative Pharm., Mie Univ. Grad. Sch. Med., 2JPN. Red Cross Ise Hosp., 3Dept. Systems Pharm., MieUniv. Grad. Sch. Med.

Oral Sessions


1-O-G1-2

Roles of prostaglandin I2 and TNF-alpha in liver regeneration in mice

Koh-ichi Yuhki1, Tomohiro Hirata1, Yoshitaka Imamichi1, Hitoshi Kashiwagi1, Koh Nakayama1,Shuh Narumiya2, Fumitaka Ushikubi1

1Dept. Pharmacol., Asahikawa Medical Univ., 2Dept. drug discovery Med., Kyoto Univ. Grad. Sch. Med.

Oral Sessions


1-O-G1-3

Macrophages promote liver repair after monocrotaline-induced liver injuryvia SDF-1/CXCR4 axis

Yoshiya Ito1,2, Fumisato Otaka1,2, Takuya Goto1,2, Kanako Hosono1,2, Ko Hatanako1,Hideki Amano1,2

1Dept. Pharm., Sch. Med., Kitasato Univ., 2Dept. Mol. Pharm., Grad. Sch. Med., Kitasato Univ.

Oral Sessions


1-O-G1-4

Injured liver-derived TNF-alpha induces muscular atrophy due to liverfibrosis

Momo Goto1, Tamaki Kurosawa1,2, Noriyuki Kaji3, Satoshi Aikiyo1, Taiki Mihara1,Madoka Uezumi2, Masashi Toyoda4, Nobuo Kanazawa5, Tatsu Nakazawa6, Akiyoshi Uezumi2,Masatoshi Hori1

1Dept. Vet. Pharmacol., Grad. Sch. Agri. Life Sci., The Univ. of Tokyo,2Muscle Aging and Regenerative Med., TokyoMetropolitan Inst. of Gerontology, 3Lab. of Vet. Pharmacol., Sch. of Vet. Med., Azabu Univ.,4Vascular Med., TokyoMetropolitan Inst. of Gerontology, 5Dept. of Surg., Tokyo Metropolitan Geriatric Hosp. and Inst. of Gerontology,6Dept. of Surg., Seibo Hosp.

Oral Sessions


1-O-G2-1

Anti-colitis effect of a new component isolated from Qing-dai (Sei-tai)

Saki Imai, Moe Miyashita, Tae Tsuboi, Yoichiro Isohama

Lab. appl. Pharmacol, Fac. of Pharm. Sci., Tokyo Univ. of Sci.

Oral Sessions


1-O-G2-2

An Indigo Naturalis constituent indigo ameliorates colitis by acceleratingwound closure

Takaaki Shimizu, Chisa Takagi, Toshinori Sawano, Jin Nakatani, Hidekazu Tanaka

Lab. Pharmacy., Grad. Sch. Life Sci., Ritsumeikan Univ.

Oral Sessions


1-O-G2-3

A close relationship between networks of interstitial cells of Cajal andgastrointestinal transit in vivo

Kamizaki Moe1, Kazuhisa Kishi1, Noriyuki Kaji2, Satoshi Iino3, Masatoshi Hori1

1Dept. Veterinary Pharmacol. The Univ. of Tokyo,2Dept. Pharmacol. Azabu Univ., 3Dept. Morphological andPhysiological Sciences Univ. of Fukui

Oral Sessions


1-O-G2-4

Construction of an in vitro human M cell model using RANKL

Tatsuya Ono1, Kazuya Masuda2, Akinobu Kajikawa1, Kenji Yokota1, Shizunobu Igimi1

1Dept. Applied Biol. Chem., Tokyo Univ. of Agr.,2Dept. Food Sci. Nutrition, Fac. Life and Environ. Sci., ShowaWoman's Univ.

Oral Sessions


1-O-G3-1

Thromboxane receptor signaling regulates lymphangiogenesis andlymphatic drainage function in diaphragm during lipopolysaccharide-induced peritonitis

Kanako Hosono1,2, Yoshiya Ito1,2, Hiromi Matsuda1,3, Seri Tsuru1,3, Ko Hatanaka1,Masataka Majima1,4, Shuh Narumiya5, Hideki Amano1,2

1Dept. Pharm., Sch. Med., Kitasato Univ., 2Dept. Mol. Pharm., Grad. Sch. Med., Kitasato Univ., 3Dept. Anesth., Sch.Med., Kitasato Univ., 4Fac. Health & Med. Sci., Kanagawa Inst. Tech., 5Dept. Drug Discovery Med., Grad. Sch.Med., Kyoto Univ.

Oral Sessions


1-O-G3-2

Differentiation-inducing factor-1 accelerates adipogenic differentiation andsuppresses the osteogenic differentiation of bone marrow-derivedmesenchymal stem cells

Shin Ishikane1, Eigo Ikushima1, Tomohiro Takiguchi1,2, Hiroaki Matsunaga1, Takehiro Kishigami1,Yumiko Toyohira1, Fumi Takahashi1

1Dept. Pharmacol., Sch. Med., Univ. Occup. & Environ. Health., 2Dept. Clin. Pharm., Fac. Med. Sci., Kyushu Univ.

Oral Sessions


1-O-G3-3

mTOR regulates skeletogenesis through complex-dependent and complex-independent pathways

Kazuya Tokumura, Sayuki Iwahashi, Kazuya Fukasawa, Takashi Iezaki, Eiichi Hinoi

Lab. Pharmacol., Dept. Bioactive Molecules, Gifu Pharmaceutical Univ

Oral Sessions


1-O-G3-4

mTORC1 hyperactivation causes skeletal defects during embryogenesis

Sayuki Iwahashi, Kazuya Tokumura, Kazuya Fukasawa, Takashi Iezaki, Eiichi Hinoi

Lab. Pharmacol., Dept. Bioactive Molecules, Gifu Pharmaceutical Univ

Oral Sessions


1-O-G3-5

NOX1/NADPH oxidase accelerates the onset of experimental arthritis

Misaki Matsumoto, Chihiro Yabe-Nishimura

Dept. Pharmacol. Kyoto Pref. Univ. Med.

Oral Sessions


Documents

1-O-B1-1 Possible Involvement of PACAP-PAC1 Receptor ......Yuki Kurauchi1,2, Risako Tanaka 2, Sumika Ryu, Makito Haruta3, Kiyotaka Sasagawa3, Takahiro Seki 1,2, Jun Ohta3, Hiroshi