-
(02)2755-4881 [email protected] (02)2755-4881
[email protected]
(02)2755-4881~4
110 176 B1 (02)8787-1888 http://www.6016.com.tw
156 12 (02)2545-9988 http://www.deloitte.com.tw
http://www.oep.com.tw
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-
105 52 6.6%
2
14.4% 105
105
3 8 3 2 4 7
2.57 5.41
105
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FDA
FDA
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1
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71 6 16
71 06 5,000,000
78 09
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88 03
89 05 GMP
89 07 (Cyntec Co., Ltd)
89 12
90 06
90 07
90 11
91 05
91 11
91 12
92 11 92 11 5 4120
93 04
97 02
97 03
98 09
99 08
100 07 TFDA PIC/S GMP
100 08 1,680,000,000
100 09
100 11
101 04
101 06 4166
102 04 FDA CGMP
102 10 NanoCarrier
103 09 Actavis Paragraph IV
103 09
2
-
103 10
103 10
103 11 HRA
103 12
104 02 Miglitol
104 10 Supernus Pharmaceutical, Inc.
105 12
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106222 7
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35
User
User
-
2.
()
()
1.
105.02.26 1. 104
2. 105(KPI)
3. 105
4. 104
5. 105
6.
105.04.12 1. 104
2.
3. 105
105.05.11 1.
2. 105 1
105.06.03 1.
2.
105.06.08 1.
105.08.11 1.1052
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3.
105.11.10 1.
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3.Bio-NutriKarihome Ltd.
4.
105.12.20 1.106
106.02.22 1.105
2.105
3.106
4.105
5.
6.
7.105(KPI)
36
-
2.
105.06.03
104
104 105 06 28 105 07 08
105 06 03 108 06 02
105 07 01
()
()(
)
37
-
()
105
1 2,000
2 2,000()4,000 2,100 0 2,100
3 4,000()6,000
4 6,000()8,000
5 8,000()10,000
6 10,000()
()
()
()
105 05 11
()
V
()
105 05 11
() 10 5 1 2 3
38
-
()
105 106 03 31
( )
( )
( )
( )
/ 17,592 0 0 0
/ 0 0 0 0
0 0 0 0
0 0 0 0
0 0 0 0
4,937 0 0 0
0 0 0 0
Praveen Tyle 0 0 0 0
0 0 0 0
/ 0 0 0 0
0 0 0 0
0 0 0 0
6,635 0 0 0
0 0 (10,000) 0
0 0 0 0
0 0 0 0
7,441 0 (3,000) 0
5,529 0 0 0
0 0 0 0
0 0 0 0
0 0 0 0
0 0 0 0
0 0 0 0
0 0 0 0
0 0 0 0
0 0 0 0
0 0 0 0
0 0 0 0
0 0 0 0
0
1,200,000 0 0
0
1,200,000 0 0
39
-
106 04 10
()
()
()
()
:
9,974,698 11.50% 0 0% 0 0%
:
9,960,666 11.48% 0 0% 0 0%
:
9,957,242 11.48% 0 0% 0 0%
7,319,830 8.44% 3,709,305 4.28% 0 0%
:
7,142,698 8.23% 0 0% 0 0
3,709,305 4.28% 7,319,830 8.44% 0 0
: 3,704,119 4.27% 0 0% 0 0
1,098,000 1.27% 0 0% 0 0
974,265 1.12% 0 0% 0 0
931,235 1.07% 0 0% 0 0
931,235 1.07% 0 0% 0 0
40
-
105 12 31
()
Cyntec Co., Ltd. 2,000 100% 0 0% 2,000 100.00%
100 100% 0 0% 100 100.00%
Orient Europharma NZ Co., Ltd. 1,702 100% 0 0% 1,702 100.00%
Pacific Orient Ltd. 0.5 50% 0 0% 0.5 50.00%
Bio-Nutri Co., Ltd. 4 100% 0 0% 4 100.00%
75,226 57.85% 7,772 5.98% 113,456 63.83%
508 30.80% 0 0% 508 30.80%
38,930 55.54% 14,247 20.32% 53,177 75.86%
5,300 18.16% 0 0% 5,300 18.16%
Orient Europharma Co., Ltd.
(Hong Kong) 19,600 100% 0 0% 19,600 100.00%
Orient Europharma (M) SDN
BHD. 2,500 100% 0 0% 2,500 100.00%
Eu Hwa Pte Ltd. 200 100% 0 0% 200 100.00%
Orient Europharma Pte Ltd. 2,382 100% 0 0% 2,382 100.00%
OEP Philippines, Inc. 442 80% 0 0% 442 80.00%
Farmatec 40 80% 0 0% 40 80.00%
OEPA, LLC. 40% 0 0% 40.00%
Orient Europharma Pty Ltd. 50 100% 0 0% 50 100.00%
Orient Pharma (Samoa) Co.,
LTD. 500 100% 0 0% 500 100.00%
OPRX Pharmaceuticals, Inc. 1,500 33.33% 0 0% 1,500 33.33%
Orient Pharma, Inc. 140 100% 0 0% 140 100.00%
Karihome Inc. 9,000 100% 0 0% 9,000 100.00%
41
-
()
/
86.12 10 3,500 35,000 3,500 35,000 1 87.04 10 10,000 100,000
10,000 100,000 2 88.09 10 15,000 150,000 15,000 150,000 3 89.06 10
19,500 195,000 19,500 195,000 4 90.06 10 50,000 500,000 32,000
320,000 / 5 91.07 10 50,000 500,000 33,920 339,200 6 91.10 10
50,000 500,000 40,000 400,000 7 92.07 10 50,000 500,000 42,000
420,000 8 93.07 10 50,000 500,000 43,260 432,600 9 94.08 10 60,000
600,000 43,910 439,104 10 95.07 10 60,000 600,000 45,389 453,891 11
95.12 10 60,000 600,000 45,768 457,687 12 96.03 10 60,000 600,000
45,857 458,567 13 96.08 10 60,000 600,000 46,356 463,567 14 96.10
10 60,000 600,000 51,214 512,140 15 96.11 10 60,000 600,000 51,400
514,002 16 97.05 10 60,000 600,000 51,451 514,512 17 97.08 10
100,000 1,000,000 57,260 572,603 18 98.01 10 100,000 1,000,000
57,268 572,683 19 98.03 10 100,000 1,000,000 57,505 575,057 20
98.06 10 100,000 1,000,000 58,683 586,838 21 98.07 10 100,000
1,000,000 60,169 601,693 22 98.10 10 100,000 1,000,000 69,296
692,961 23 98.12 10 100,000 1,000,000 69,949 699,491 24 99.08 10
100,000 1,000,000 81,141 811,410 25 100.01 10 100,000 1,000,000
81,163 811,637 26 100.06 10 100,000 1,000,000 86,747 867,471 27
186 12 01
287 04 13()
388 09 28()
489 07 11()
590 06 08()
691 07 02()
791 09 10()
892 07 14
993 07 13
10: 94 08 18
11: 95 07 03
12: 96 01 26
13: 96 05 11
14: 96 08 03
15: 96 10 15
16: 96 11 14
17: 97 05 19
18: 97 08 26
19: 98 01 08
20: 98 03 11
21: 98 06 26
22: 98 07 30
23: 98 10 12
24: 98 12 31
25: 99 08 12
26: 100 01 11
27: 100 06 24
42
-
86,747,119 13,252,881 100,000,000
() 106 04 10
() 0 3 30 6,447 32 6,512
() 0 1,965,950 38,005,600 40,266,010 6,509,559 86,747,119
(%) 0 2.27 43.81 46.42 7.50 100.00
()
1.
106 04 10
() () (%)
1 999 1,321 274,332 0.32
1,000 5,000 4,205 8,163,398
9.41
5,001 10,000 519 4,209,109
4.85
10,001 15,000 143 1,866,545
2.15
15,001 20,000 89 1,649,482
1.90
20,001 30,000 68 1,788,608
2.06
30,001 40,000 45 1,643,217
1.90
40,001 50,000 31 1,410,400
1.63
50,001 100,000 45 3,243,653
3.74
100,001 200,000 27 3,852,816
4.44
200,001 400,000 6 1,650,266
1.90
400,001 600,000 1 487,000
0.56
600,001 800,000 0 0 0
800,001 1,000,000 4 3,641,735
4.20
1,000,001 8 52,866,558
60.94
6,512 86,747,119 100.00
2.
43
-
()
106 04 10
() (%)
9,974,698 11.50
9,960,666 11.48
9,957,242 11.48
7,319,830 8.44
7,142,698 8.23
3,709,305 4.28
3,704,119 4.27
1,098,000 1.27
974,265 1.12
931,235 1.07
931,235 1.07
()
104 105 106 106 03 31 106 05 10 ( 9)
( 2)
70.2 70.8 80.6
40.1 46.4 60.0
61.24 60.04 72.38
( 3)
33.33 36.25 36.98
31.53 ( 1)
86,747 86,747 86,747
2.57 5.41 2.02
( 4) 2.57 ( 1)
1.80 ( 1)
( 5)
( 6) 23.83
23.83 ( 1)
( 7) 34.02 ( 1)
( 8) 2.94% ( 1) 1105 2 3 4 5
6 7 8 9
106 05 10
44
-
()
1.
10%
20%
105 06 03
50%
2.
106 02 22 105
1.8
156,144,815
() 105
()
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;
10%
2.
105 02 26 105
105
3.
(1) 105
106 05 10 14,280,455
0
(2)
105
45
-
4. 104 12 31
14,282,914 0
14,217,914 65,000 105
0
()
46
-
()
1.
(1)
(2)()
2.
105 (%)
1,974,541 37.74
3,257,502 62.26
5,232,043 100.00
3.
..
ArieForma
4.
105
Supernus
Trokendi XR(FDA)
106
47
-
()
A.
1.
IMS Health
2015
1.07 0.8%
2016
2015 3.3% 1.1
2526%
2016~2020 2.33.3 2016~2020
(Compound Annual Growth Rate, CAGR) 47%
2005 33%
2020 50%
2020 2015 49%
(specialty medicines)
2020 35%
2.
(
)(Original)
(BE Generics)(Non-BE Generics)
Non-BE Generics
48
-
3.
IMS Health 2016
CAGR 58%2016 830880
480530
440480 42%
CAGR 20142019
5%
II
CAGR
2015 ASEAN Community
2013
(PIC/S)
B.
1.
ITIS 2015
1,147 2014 1.5% 2016
1,1632015 52.4% 601
2.
3.
2014
49
-
C.
1.
2014 5.9% KANTAR WORLDPANEL() 2016 65 2014-19 7.69%
2.
90%
KANTAR WORLDPANEL 2016 80%
3.
70 2014CNCA2015 2018 500 700
AA DHACLA
()
1.
105 106 03 31
363,385 68,157
2.
104104 105
50
-
()
1.
(1)
(2)
(3)
2.
(1)
()
106
(2)
(3)
(4)
()()(
)
51
-
()
1.
2.
(1)
104105 66%104105 97%
KANTAR WORLDPANEL 2016() 11% 200
(2)
3.
(1)
(2)
3
52
-
(3)
PIC/SFDA GMP
(4)
4.
(1)
A.
B.
C.
D.
104 105 2000
E.
2016 240 530 GDP 5-7%
F.
(2)
A.
B.
53
-
()
1.
2.
()
()
1.
%
104 105 106()
%
%
%
1 DGC 1,378,559 56.81% DGC 1,869,807 64.20% DGC 301,246
54.00%
2 PFM 285,231 11.75% PFM 332,148 11.40% PFM 78,838 14.13%
762,711 31.44% 710,444 24.40% 177,732 31.87%
2,426,501 100.00%
2,912,399 100.00%
557,816 100.00%
()
2.
54
-
()
()
104 105
2,505,070 1,015,491 1,999,736 823,486 259,318 128,840
3,143,042 1,899,547 993,477 576,985 2,267,255 1,601,492
3,826,545 1,708,631 2,905,519 1,303,778 987,010 524,625
()
104 105
106 04 30
() 299 304 304
172 177 172
352 371 358
823 852 834
37.0 37.57 37.30
3.73 4.43 4.30
10 11 11
136 151 157
546 565 546
131 125 120
()
1
: 2
55
-
() ()
()
()
(1)(2)(3)(4)
FSC FSC(Forest Stewardship Council)
i. 100%
ii.
() ()
() 85%
() 43
()
()
56
-
()
()
(1)
(///)
(2)
(3)
(4)
()
57
-
()
(5)
A.
B.
C.
D.
(6)
(7)
()
(1) 105 672
58
-
(2)
(on the job training)105 28,346 105 1,4607,973.5
(3) 105 2,698 339
(4) 105 205
(5)
(6) e-Learning
e-Learning
(7) 105 92%
(8)
(9) (OEP Global )
()
()
()
15 55
59
-
25
15
6%
()
(1)
(2)
(3)(OEP Global )
(4)
(5)
(6)
" """
60
-
()
DGC 85.10.01
PFM 87.2.20
106.02.23~110.03.29
105.07.12~110.06.27
106.03.17~107.03.17
61
-
( )
1.
( 1)
106 03 31
(3) 105 104 103
() 102 101
3,542,860 2,917,647 2,782,070 2,839,112 2,309,186 3,222,963
1,940,426 1,718,350 1,595,174 1,497,865 1,532,958 1,980,789
85,725 88,068 86,443 84,960 84,281 83,319
917,218 750,352 647,446 849,330 590,349 928,861
6,486,229 5,474,417 5,111,133 5,271,267 4,516,774 6,215,932
1,341,042 1,368,534 1,088,988 1,095,427 1,117,699 1,141,195
( 2) 1,524,679 1,227,783 1,240,295 1,282,519 ( 2)
1,229,186 721,415 604,185 658,773 407,025 1,120,703
2,570,228 2,089,949 1,693,173 1,754,200 1,524,724 2,261,898
( 2) 2,246,094 1,831,968 1,899,068 1,689,544 ( 2)
3,144,751 2,891,393 2,831,558 2,856,785 2,399,248 3,208,179
867,471 867,471 867,471 867,471 867,471 867,471
258,542 257,647 255,505 254,534 254,576 258,690
1,860,812 1,547,318 1,469,304 1,417,220 1,068,204 2,035,895
( 2) 1,391,173 1,330,509 1,272,352 903,384 ( 2)
157,926 218,957 239,278 317,560 208,997 46,123
771,250 493,075 586,402 660,282 592,802 745,855
3,916,001 3,384,468 3,417,960 3,517,067 2,992,050 3,954,034
( 2) 3,228,323 3,279,165 3,372,199 2,827,230 ( 2)
1 2 105 106 3 106 03 31
62
-
2.
( 1)
106 03 31
(3) 105 104 103
() 102 101
5,232,043 4,907,250 5,000,241 4,665,102 4,513,420 1,330,394
2,413,142 2,166,233 1,988,402 1,779,220 1,856,752 619,230
450,853 263,543 213,442 65,875 185,066 181,005
15,731 (58,436) 19,350 374,473 46,156 22,421
466,584 205,107 232,792 440,348 231,222 203,426
383,690 135,894 131,197 436,441 160,594 151,026
( ) 383,690 135,894 131,197 436,441 160,594 151,026
( ) (63,505) (27,127) (74,308) 117,624 141,873 (113,404)
320,185 108,767 56,889 554,065 302,467 37,622
469,606 223,156 195,918 506,780 231,920 175,083
(85,916) (87,262) (64,721) (70,339) (71,326) (24,057)
408,608 196,489 118,670 622,399 376,671 63,280
(88,423) (87,722) (61,781) (68,334) (74,204) (25,658)
() ( 2) 5.41 2.57 2.26 5.84 2.67 2.02
1 2 3 106 03 31
63
-
3.
( 1)
105 104 103
() 102 101
1,136,513 1,103,780 1,172,876 1,387,745 1,336,964
699,683 719,904 631,601 532,026 548,255
35,674 36,727 38,587 37,974 36,578
3,129,238 2,444,025 2,354,094 2,393,583 1,718,793
5,001,108 4,304,436 4,197,158 4,351,328 3,640,590
908,621 1,034,617 972,042 941,902 887,465
( 2) 1,190,762 1,110,837 1,086,770 1,052,285
947,736 378,426 393,558 552,641 353,877
1,856,357 1,413,043 1,365,600 1,494,543 1,241,342
( 2) 1,569,188 1,504,395 1,639,411 1,406,162
867,471 867,471 867,471 867,471 867,471
258,542 257,647 255,505 254,534 254,576
1,860,812 1,547,318 1,469,304 1,417,220 1,068,204
( 2) 1,391,173 1,330,509 1,272,352 903,384
157,926 218,957 239,278 317,560 208,997
3,144,751 2,891,393 2,831,558 2,856,785 2,399,248
( 2) 2,735,248 2,692,763 2,711,917 2,234,428
1 2 105 106
64
-
4.
( 1)
105 104 103
() 102 101
2,780,179 2,858,863 3,061,914 3,167,680 3,168,391
1,155,675 1,120,830 1,014,583 988,037 1,099,416
208,107 117,759 100,522 68,855 203,564
313,960 170,617 188,307 446,054 122,564
522,067 288,376 288,829 514,909 326,128
469,606 223,156 195,918 506,780 231,920
( ) 469,606 223,156 195,918 506,780 231,920
( ) (60,998) (26,667) (77,248) 115,619 144,751
408,608 196,489 118,670 622,399 376,671
() ( 2) 5.41 2.57 2.26 5.84 2.67
1 2
()
105
104
103
102
101
65
-
1.
( 1)
( 3)
106 03 31
( 1) 105 104 103
() 102 101
(%) 39.63 38.18 33.13 33.28 33.76 36.39
(%) 265.16 238.94 252.14 278.79 221.73 256.20
(%) 264.19 213.20 255.47 259.18 206.60 282.42
(%) 177.08 144.74 149.33 144.85 122.63 191.66
(%) 2,919.07 1,833.20 2,910.48 8,614.08 2,863.17 5,412.77
() 7.62 7.33 7.35 6.48 6.21 7.24
47.90 49.79 49.65 56.32 58.78 50.41
() 2.88 2.82 2.67 2.76 2.93 2.80
() 7.77 7.28 7.79 8.82 9.13 8.48
126.74 129.43 136.70 132.24 124.57 130.36
() 2.86 2.96 3.23 3.08 3.08 2.71
() 0.87 0.93 0.96 0.95 1.02 0.84
(%) 6.65 2.75 2.66 9.01 3.78 2.43
(%) 10.51 4.00 3.78 13.41 5.56 3.84
(%) 53.79 23.64 26.84 50.76 26.65 23.45
(%) 7.33 2.77 2.62 9.36 3.56 11.35
() 5.41 2.57 2.26 5.84 2.67 2.02
(%)
8.29 47.06 29.81 -2.35 28.74 19.19
( 2) 63.83 72.39 41.54 33.37 63.90 60.83
-1.06 10.84 3.77 -4.49 5.69 3.96
1.40 1.62 1.70 3.10 1.72 1.25
1.04 1.05 1.04 1.09 1.05 1.02
20%
1.:
2.
3.
66
-
2.
( 1)
( 3)
105 104 103
() 102 101
(%) 37.12 32.83 32.54 34.35 34.10
(%)
584.91 454.20 510.63 640.84 502.16
(%) 125.08 106.68 120.66 147.33 150.65
(%) 56.85 51.46 64.56 64.29 75.40
(%) 6,009.75 4,920.73 4,856.74 11,288.81 4,750.34
() 7.33 7.29 6.88 6.00 5.72
50 50 53 61 64
() 2.91 3.28 3.13 3.02 2.97
() 7.00 5.64 6.00 7.92 7.98
125 111 117 121 122
() 3.92 4.23 5.26 5.86 5.94
() 0.60 0.67 0.72 0.79 0.90
(%) 10.25 5.37 4.70 12.78 6.77
(%) 15.56 7.80 6.89 19.28 10.27
(%) 60.18 33.24 33.30 59.36 37.60
(%) 16.89 7.81 6.40 16.00 7.32
() 5.41 2.57 2.26 5.84 2.67
(%)
7.98 18.64 49.13 25.46 36.61
( 2) 83.82 80.82 75.50 71.26 81.70
-1.99 1.61 10.08 2.16 7.83
1.23 1.40 1.40 1.54 1.17
1.04 1.05 1.06 1.07 1.04
20%
1.:
2.:
3.
4. 105
1 106 03 31
2101
3
1.
(1)
(2)
2.
(1)
(2)
(3)
3.
(1)()
()
(2)365
(3)
67
-
(4)() (
)
(5)365
(6)
(7)
4.
(1)
(2)
(3)
(4)
5.
(1)
(2)(
)
(3)()(
)
6.
(1)()
(2) ()
68
-
()
69
Administrator
User
User
User
User
USER
User
-
105 104 12 31
105 104 1 1 12 31
105 104 12
31 105 104 1 1 12 31
70
-
105
105
105
Orient Europharma NZ Co., Ltd. Cyntec Co., Ltd.
Orient Europharma Co., Ltd.Orient Europharma (M) SDN
BHD.Orient
Europharma Pte Ltd.OEP Philippines, Inc.Eu Hwa Pte Ltd.
Orient Europharma Co., Ltd.
Orient Europharma NZ Co.,
Ltd. Cyntec Co., Ltd. Orient Europharma Co., Ltd.
Orient Europharma (M) SDN BHD.Orient Europharma Pte Ltd.OEP
Philippines,
Inc.Eu Hwa Pte Ltd. Orient Europharma Co.,
Ltd.
71
-
105
104 12 31
31,593 35,084 Cyntec Co., Ltd.
389,516 296,656
65,262 58,170 Orient Europharma Co., Ltd.
41,479 75,370
105 104 1 1 12 31
224,111 103,547
72
-
1.
2.
3.
4.
5.
6.
73
-
105
0920123784
0920123784
1 0 6 2 2 2
74
USER
USER
User
User
-
105 104 12 31
1051231 1041231
1100 $ 84,744 2 $ 154,457 4 1147 1,607 - 1,607 - 1150 135,991 3
95,040 2 1170 256,509 5 262,923 6 1200 32,078 1 18,381 1 1220 5,659
- - - 130X 577,559 11 520,679 12 1410 12,909 - 8,809 - 1470 29,457
1 41,884 1 11XX 1,136,513 23 1,103,780 26
1523 2,894 - 15,571 - 1543 229 - 229 - 1550 3,051,873 61
2,366,528 55 1600 699,683 14 719,904 17 1780 35,674 1 36,727 1 1840
54,040 1 30,063 - 1990 20,202 - 31,634 1 15XX 3,864,595 77
3,200,656 74
1XXX $ 5,001,108 100 $ 4,304,436 100
2100 $ 300,000 6 $ 280,000 7 2150 532 - 12,334 - 2170 193,886 4
257,169 6 2219 338,467 7 370,372 9 2230 - - 20,905 - 2320 60,576 1
78,300 2 2305 15,160 - 15,537 - 21XX 908,621 18 1,034,617 24
2540 539,424 11 30,000 1 2570 334,760 7 274,369 6 2640 47,549 1
46,682 1 2670 26,003 - 27,375 1 25XX 947,736 19 378,426 9
2XXX 1,856,357 37 1,413,043 33
3110 867,471 18 867,471 20 3200 258,542 5 257,647 6 3310 283,836
6 261,520 6 3320 4,469 - 4,469 - 3350 1,572,507 31 1,281,329 30
3300 1,860,812 37 1,547,318 36 3400 157,926 3 218,957 5
3XXX 3,144,751 63 2,891,393 67
$ 5,001,108 100 $ 4,304,436 100
106 2 22
75
User
User
User
User
-
105 104 1 1 12 31
105 104
4000
$ 2,780,179 100 $ 2,858,863 100
5000 1,624,504 58 1,738,033 61
5900 1,155,675 42 1,120,830 39
5910
1,702 - 682 -
5920
682 - 325 -
5950 1,154,655 42 1,120,473 39
6100 435,762 16 393,301 14 6200 329,520 12 329,336 11 6300
181,266 6 280,077 10 6000 946,548 34 1,002,714 35
6900 208,107 8 117,759 4
7190
63,326 2 33,566 1
7050 ( 8,834 ) - ( 5,982 ) - 7230
22,536 1 26,240 1
7070
236,932 8 116,793 4
7000
313,960 11 170,617 6
76
User
-
105 104
7900 $ 522,067 19 $ 288,376 10
7950 52,461 2 65,220 2
8200 469,606 17 223,156 8
8311
( 3,063 ) - ( 7,232 ) -
8330
2,575 - ( 344 ) -
8349
521 - 1,229 -
8310 33 - ( 6,347 ) -
8362
( 12,677 ) - ( 7,964 ) -
8380
( 60,686 ) ( 2 ) ( 16,550 ) ( 1 )
8399
12,332 - 4,194 -
8360 ( 61,031 ) ( 2 ) ( 20,320 ) ( 1 )
8300
( 60,998 ) ( 2 ) ( 26,667 ) ( 1 )
8500 $ 408,608 15 $ 196,489 7
9710 $ 5.41 $ 2.57 9810 $ 5.38 $ 2.56
106 2 22
77
User
User
User
-
10
5
1
04
1
1
1
2
31
A1
104
1
1
$
867,4
71
$
255,5
05
$
241,9
37
$
4,4
69
$
1,2
22,8
98
$
54,9
77
$
184,3
01
$
2,8
31,5
58
103
B1
-
-
19,5
83
-
(
19,5
83 )
-
-
-
B5
-
-
-
-
(
138,7
95 )
-
-
(
138,7
95 )
C7
-
408
-
-
-
-
-
408
M7
-
1,7
34
-
-
-
(
1 )
-
1,7
33
D1
104
-
-
-
-
223,1
56
-
-
223,1
56
D3
104
-
-
-
-
(
6,3
47 )
41,3
43
(
61,6
63 )
(
26,6
67 )
D5
104
-
-
-
-
216,8
09
41,3
43
(
61,6
63 )
196,4
89
Z1
104
12
31
867,4
71
257,6
47
261,5
20
4,4
69
1,2
81,3
29
96,3
19
122,6
38
2,8
91,3
93
104
B1
-
-
22,3
16
-
(
22,3
16 )
-
-
-
B5
-
-
-
-
(
156,1
45 )
-
-
(
156,1
45 )
C7
-
1,3
02
-
-
-
-
-
1,3
02
M7
-
(
407 )
-
-
-
-
-
(
407 )
D1
105
-
-
-
-
469,6
06
-
-
469,6
06
D3
105
-
-
-
-
33
(
29,3
12 )
(
31,7
19 )
(
60,9
98 )
D5
105
-
-
-
-
469,6
39
(
29,3
12 )
(
31,7
19 )
408,6
08
Z1
105
12
31
$
867,4
71
$
258,5
42
$
283,8
36
$
4,4
69
$
1,5
72,5
07
$
67,0
07
$
90,9
19
$
3,1
44,7
51
10
6
2
22
78
User
User
User
User
-
105 104 1 1 12 31
105 104
A10000 $ 522,067 $ 288,376 A20010 A20100 22,904 22,830 A20200
1,312 2,165 A20300 ( 139 ) ( 167 ) A20900 8,834 5,982 A21200 ( 111
) ( 154 ) A22300
( 236,932 ) ( 116,793 )
A22500 ( 569 ) - A23200 ( 131 ) - A23700
1,826 ( 12,068 )
A29900 5,747 12,923 A30000 A31130 ( 40,951 ) ( 5,760 ) A31150
6,553 65,027 A31180 ( 13,697 ) 8,639 A31200 ( 64,453 ) ( 10,678 )
A31230 ( 4,100 ) ( 5,836 ) A31240 12,427 ( 10,433 ) A32130 ( 11,802
) 1,895 A32150 ( 63,283 ) ( 78,736 ) A32180 ( 31,954 ) 32,615
A32230 ( 377 ) ( 6,646 ) A32240 ( 2,196 ) ( 453 ) A33000 110,975
192,728 A33100 111 154 A33300 ( 8,785 ) ( 5,944 ) A33500 ( 29,758 )
5,936 AAAA 72,543 192,874
79
User
-
105 104
B01800 ( $ 52,500 ) ( $ 18,000 ) B02200 ( 2,500 ) - B02300 1,660
- B02700 ( 3,435 ) ( 111,133 ) B02800 1,321 - B04500 ( 259 ) ( 305
) B07600 413 323 B06700 11,432 ( 6,189 ) BBBB ( 43,868 ) ( 135,304
)
C00200 20,000 150,000 C01600 570,000 110,000 C01700 ( 78,300 ) (
182,105 ) C04300 ( 1,372 ) ( 678 ) C04500 ( 156,145 ) ( 138,795 )
C05400 ( 516,349 ) - C05500 63,778 - CCCC ( 98,388 ) ( 61,578 )
EEEE ( 69,713 ) ( 4,008 )
E00100 154,457 158,465
E00200 $ 84,744 $ 154,457
106 2 22
80
User
User
User
-
105 104 1 1 12 31
71 6
( )
( )
( )
( )
( )
( )
( )
( )
( )
( )
( )
( )
106 2 22
81
-
( ) 106
IFRS IAS
IFRIC SIC
1050050021 1050026834
106 IASB
106 IFRS IAS IFRIC SIC IFRSs
IASB 1
2010-2012 2014 7 1 2
2011-2013 2014 7 1
2012-2014 2016 1 1 3
IFRS 10IFRS 12 IAS 28
2016 1 1
IFRS 11 2016 1 1
IFRS 14 2016 1 1
IAS 1 2016 1 1
IAS 16 IAS 38
2016 1 1
IAS 16 IAS 41 2016 1 1
IAS 19 2014 7 1
IAS 27 2016 1 1
IAS 36 2014 1 1
IAS 39
2014 1 1
IFRIC 21 2014 1 1
1
2 2014 7 1
IFRS 2 2014 7 1
IFRS 3 IFRS 13
2014 7 1
82
-
3 IFRS 5 2016 1 1
2016 1 1
106 IFRSs
1. IAS 36
IAS 36
2 3
106
2. 2010-2012
2010-2012 IFRS 3 IFRS
8
IFRS 3 IAS
39 IFRS 9
106
IFRS 8
106 IFRS 8
106 IFRS 13
83
-
IAS 24
106
3. IAS 16 IAS 38
IAS 16
IAS 38
(1)
(2)
106
4.
106 IFRSs
IFRSs
10%
84
-
106
106
IFRSs
( ) IASB IFRSs
IASB IFRSs
IFRS 9 IFRS 15 107
IASB 1
2014-2016 2
IFRS 2 2018 1 1
IFRS 9 2018 1 1
IFRS 9 IFRS 7 2018 1 1
IFRS 10 IAS 28
IFRS 15 2018 1 1
IFRS 15 IFRS 15 2018 1 1
IFRS 16 2019 1 1
IAS 7 2017 1 1
IAS 12
2017 1 1
IAS 40 2018 1 1
IFRIC 22 2018 1 1
1
2 IFRS 12 2017 1 1
IAS 28 2018 1 1
85
-
1. IFRS 15
IFRS 15
IAS 18 IAS 11
IFRS 15
(1)
(2)
(3)
(4)
(5)
IFRS 15
(1)
(2)
(3)
IFRS 15
IFRS 15
86
-
2. IFRS 16
IFRS 16 IAS 17
IFRS 16
IAS 17
IFRS 16
( )
( )
1
3
1. 1
2. 2 1
3. 3
87
-
( )
1.
2. 12
3. 12
1.
2. 12
3. 12
( )
88
-
( )
( )
1.
89
-
2.
90
-
( )
91
-
( )
( )
92
-
( )
1.
(1)
A.
93
-
B.
3
(2)
210
94
-
95
-
(3)
2.
(1)
(2)
( )
1.
(1)
(2)
(3)
(4)
(5)
96
-
2.
3.
( )
1.
2.
97
-
( )
1.
2.
( )
1.
10%
2.
98
-
3.
99
-
1051231 1041231
$ 985 $ 1,018 81,759 151,439 3
2,000 2,000 $ 84,744 $ 154,457
3
1051231 1041231
3
0.66% 0.80%
1051231 1041231
CEL SCI Co., Ltd. $ 2,894 $ 15,571
1051231 1041231
$ 700 $ 700 ( 471 ) ( 471 ) $ 229 $ 229
100
-
1051231 1041231
3
$ 1,607 $ 1,607
3
1051231 1041231
3
0.810%1.065% 0.950%1.205%
1051231 1041231
$ 136,145 $ 95,194 154 154 $ 135,991 $ 95,040
$ 260,351 $ 267,135 3,842 4,212 $ 256,509 $ 262,923
120
210
210 100%
210
101
-
1051231 1041231
$ 238,903 $ 253,595 120 17,560 9,252 121 210 46 76 $ 256,509 $
262,923
104 1 1 $ - $ 22,102 $ 22,102 - ( 167 ) ( 167 ) 104 12 31 $ - $
21,935 $ 21,935
105 1 1 $ - $ 21,935 $ 21,935 - ( 139 ) ( 139 ) 105 12 31 $ - $
21,796 $ 21,796
1051231 1041231
$ 565,232 $ 469,533 652 12,896 11,675 12,653 - 25,597 $ 577,559
$ 520,679
105 104 1,624,504
1,738,033 105
1,826 5,747 104
12,068 12,923
102
-
1051231 1041231
$ 2,984,525 $ 2,347,428 $ 67,348 $ 19,100
( )
1051231 1041231
Cyntec Co., Ltd. $ 1,064,699 $ 938,833
Bio-Nutri Co., Ltd. 835,711 723,787
619,085 444,186 431,089 203,303 Orient Europharma NZ Co.,
Ltd. 31,593 35,084
2,348 2,235
$ 2,984,525 $ 2,347,428
1051231 1041231
Cyntec Co., Ltd. 100.00% 100.00%
Bio-Nutri Co., Ltd. 100.00% 100.00%
57.85% 57.84% 55.54% 67.93% Orient Europharma NZ Co.,
Ltd. 100.00% 100.00%
100.00% 100.00% - -
105
104
104 3 5 12
105 4 105 7
104
105 12 31 57.84% 57.85%
103
-
104 105
1,734 493 105
105
33
105 3 35,000
15 Cyntec Co., Ltd. Bio-Nutri Co., Ltd.
15,086 4,340 4,340
55.54%6.19% 6.19%
67.93% 67.92%
105
53
105 1 2,500
100% 105 11
131
( )
1051231 1041231
$ 63,279 $ 14,988 4,069 4,112 $ 67,348 $ 19,100
1.
1051231 1041231
18.16% 20.00%
104
-
104 1 18,000
1,800 30.77%
104 8
104 12 31 30.77% 20.00%
105 9 11
105 12 31 20.00%
18.16% 104
105 408
1,302
IFRSs
1051231 1041231
$ 351,713 $ 74,939 ( 3,260 ) -
$ 348,453 $ 74,939
$ 63,279 $ 14,988
105 104
$ - $ -
( $ 30,439 ) ( $ 15,061 ) - -
( $ 30,439 ) ( $ 15,061 )
2.
105 104
( $ 43 ) $ 652 - - ( $ 43 ) $ 652
105
-
104 1 1 $ 328,578 $ 344,489 $ 4,122 $ 12,181 $ 10,225 $ 7,061 $
706,656 92,140 15,447 81 770 1,137 1,558 111,133 - - ( 675 ) ( 650
) ( 1,215 ) ( 1,041 ) ( 3,581 ) 104 12 31 $ 420,718 $ 359,936 $
3,528 $ 12,301 $ 10,147 $ 7,578 $ 814,208
104 1 1 $ - $ 62,879 $ 1,762 $ 4,163 $ 3,971 $ 2,280 $ 75,055 -
- ( 675 ) ( 650 ) ( 1,215 ) ( 1,041 ) ( 3,581 ) - 14,848 968 2,215
2,936 1,863 22,830 104 12 31 $ - $ 77,727 $ 2,055 $ 5,728 $ 5,692 $
3,102 $ 94,304
104 12 31 $ 420,718 $ 282,209 $ 1,473 $ 6,573 $ 4,455 $ 4,476 $
719,904
105 1 1 $ 420,718 $ 359,936 $ 3,528 $ 12,301 $ 10,147 $ 7,578 $
814,208 - 1,251 848 - 970 366 3,435 - - ( 1,172 ) ( 4,920 ) ( 3,512
) ( 607 ) ( 10,211 ) 105 12 31 $ 420,718 $ 361,187 $ 3,204 $ 7,381
$ 7,605 $ 7,337 $ 807,432
105 1 1 $ - $ 77,727 $ 2,055 $ 5,728 $ 5,692 $ 3,102 $ 94,304 -
- ( 1,172 ) ( 4,168 ) ( 3,512 ) ( 607 ) ( 9,459 ) - 15,536 923
1,851 2,614 1,980 22,904 105 12 31 $ - $ 93,263 $ 1,806 $ 3,411 $
4,794 $ 4,475 $ 107,749
105 12 31 $ 420,718 $ 267,924 $ 1,398 $ 3,970 $ 2,811 $ 2,862 $
699,683
16 50
10 20
3 5
2 8
5
3 10
1 10
106
-
107 5
106 $ 600
107 150
1051231 1041231
$ 250,000 $ 230,000 50,000 50,000 $ 300,000 $ 280,000
$ 940,000 $ 1,030,000
1.035%1.150% 1.120%1.170%
1.120% 1.150%
1051231 1041231
$ 500,000 $ 93,351 100,000 14,949 ( 60,576 ) ( 78,300 ) $
539,424 $ 30,000
$ 262,000 $ 652,000
1.490%1.700% 1.516%1.780%
1.150% 1.576%
119 4
107
-
( )
6%
( )
6 3%
3
1051231 1041231
$ 83,476 $ 86,937 ( 35,927 ) ( 40,255 ) $ 47,549 $ 46,682
104 1 1 $ 80,099 ( $ 40,196 ) $ 39,903 689 - 689 ( 666 ) - ( 666
) 1,593 ( 812 ) 781 1,616 ( 812 ) 804
- ( 334 ) ( 334 ) 7 - 7
108
-
$ 5,288 $ - $ 5,288 2,271 - 2,271 7,566 ( 334 ) 7,232 - ( 1,257
) ( 1,257 ) ( 2,344 ) 2,344 - 104 12 31 86,937 ( 40,255 ) 46,682
524 - 524 ( 2,182 ) - ( 2,182 ) 1,296 ( 609 ) 687 ( 362 ) ( 609 ) (
971 )
- 357 357 88 - 88 2,655 - 2,655 ( 37 ) - ( 37 ) 2,706 357 3,063
- ( 1,225 ) ( 1,225 ) ( 5,805 ) 5,805 - 105 12 31 $ 83,476 ( $
35,927 ) $ 47,549
1.
2
2.
3.
109
-
1051231 1041231
1.25% 1.50% 3.00% 3.00% 2.12% 2.35%
1051231 1041231
0.25% ( $ 2,481 ) ( $ 2,672 ) 0.25% $ 2,585 $ 2,787
0.25% $ 2,534 $ 2,739 0.25% ( $ 2,445 ) ( $ 2,640 )
110% ( $ 471 ) ( $ 586 ) 90% $ 477 $ 595
1051231 1041231
1 $ 1,573 $ 1,746 12 12
( )
1051231 1041231
100,000 100,000 $ 1,000,000 $ 1,000,000 $ 867,471 $ 867,471
10
110
-
( )
1051231 1041231
(1) $ 242,321 $ 242,321
11,888 11,888
(2) 2,623 3,030
1,710 408 $ 258,542 $ 257,647
1.
2.
( )
104 5
105 6 3
10%
( )
111
-
20%
98 6 10
50%
25%
1010012865
1010047490 1030006415
IFRSs
105 6 3 104 6 30
104 103
104 103 104 103
$ 22,316 $ 19,583 156,145 138,795 $ 1.80 $ 1.60 $ 178,461 $
158,378
( )
IFRSs
18,648 11,677
IFRSs
IFRSs 3,058
112
-
( )
1.
105 104
$ 96,319 $ 54,977
( 35,315 ) 49,811
6,003 ( 8,468 ) - ( 1 ) $ 67,007 $ 96,319
2.
105 104
$ 122,638 $ 184,301
( 12,677 ) ( 7,964 )
2,155 1,354
( 25,371 ) ( 66,361 )
4,174 11,308 $ 90,919 $ 122,638
105 104
$ 2,764,643 $ 2,844,488 15,536 14,375 $ 2,780,179 $
2,858,863
113
-
( )
105 104
$ 4,254 $ 4,343 111 154 37,041 10,841
10,871 10,366 11,049 7,862 58,961 29,069
$ 63,326 $ 33,566
( )
105 104
$ 22,489 $ 26,942 569 -
131 - ( 653 ) ( 702 ) $ 22,536 $ 26,240
( )
105 104
$ 22,904 $ 22,830 1,312 2,165 $ 24,216 $ 24,995
$ 22,904 $ 22,830
$ 1,312 $ 2,165
114
-
( )
105 104
$ 408,115 $ 386,283
14,572 14,400
( 971 ) 804 - 900 $ 421,716 $ 402,387
$ 421,716 $ 402,387
104 5 105 6 3
1% 10%
106 2 22 105 2 26
105 104 20,162 14,283
104
14,218 104
105
106 105
104 6 30 103
103
$ 14,783 $ -
115
-
104 6 30
103
$ 14,783 $ - $ 15,895 $ -
104
104
( )
105 104
( $ 18,606 ) $ 29,700 3,835 3,857 248 ( 269 ) 66,984 47,554 - (
15,622 ) $ 52,461 $ 65,220
105 104
$ 522,067 $ 288,376
$ 88,751 $ 49,023 ( 89 ) ( 188 ) 27,072 27,188 3,835 3,857 (
67,356 ) 1,231 - ( 15,622 )
248 ( 269 ) $ 52,461 $ 65,220
17%
116
-
106 105
10%
( )
105 104
$ 2,155 $ 1,354
521 1,229
10,177 2,840
$ 12,853 $ 5,423
( )
1051231 1041231
$ 5,659 $ - $ - $ 20,905
( )
1051231 1041231
$ 18,850 $ 12,949 8,972 8,824 1,819 1,508
577 1,543 390 216 170 368 30,778 25,408
18,607 - 4,655 4,655 $ 54,040 $ 30,063
117
-
1051231 1041231
$ 294,384 $ 222,953 18,680 25,009 16,103 22,107
3,819 3,819 1,774 481 $ 334,760 $ 274,369
( )
105 12 31
$ 4,655 $ 4,655 108
105 12 31
$ 18,607 115
( )
1051231 1041231
87 $ 1,572,507 $ 1,281,329
$ 171,356 $ 174,287
105 104 10.90%
15.19%
87
105
118
-
( )
103
105 104
$ 5.41 $ 2.57 $ 5.38 $ 2.56
105 104
$ 469,606 $ 223,156
105 104
86,747 86,747 474 453
87,221 87,200
119
-
104 3 5 12
104 12 31 58.04%
57.84%
105 4
105 7
105 12 31 57.84%
57.85%
105 3
105 12 31
67.93% 67.92%
105
( )
120
-
( )
1.
(1)
(2)
(3)
105 12 31
$ 2,894 $ - $ - $ 2,894
104 12 31
$ 15,571 $ - $ - $ 15,571
105 104
2.
121
-
( )
1051231 1041231
1 $ 510,929 $ 532,408 2 3,123 15,800
3 1,432,885 1,028,175 4 121 97
1
2
3
4
( )
1.
(1) (2)
122
-
(1)
105 104
1% 1%
1%
1%
1%
105 104 105 104
$ 2,018 $ 2,270 ( $ 124 ) ( $ 56 )
(2)
3
1% 105 104
8,964 3,847
123
-
(3)
2.
3.
105 12 31
1 1 3 3 1 1 5 5
$ 250,162 $ 50,055 $ - $ - $ -
737 1,475 65,138 534,105 21,448 $ 250,899 $ 51,530 $ 65,138 $
534,105 $ 21,448
124
-
104 12 31
1 1 3 3 1 1 5 5
$ 280,117 $ - $ - $ - $ -
8,730 17,461 53,155 8,261 25,771 $ 288,847 $ 17,461 $ 53,155 $
8,261 $ 25,771
( )
105 104
$ 27,809 $ 17,986
2,931 2,366
$ 30,740 $ 20,352
( )
105 104
$ 234,101 $ 235,319
( )
1051231 1041231
$ 9,924 $ 2,714
214 407
$ 10,138 $ 3,121
$ 15,833 $ 11,868
53 -
$ 15,886 $ 11,868
105 104
125
-
( )
1051231 1041231
$ 52,958 $ 58,617
$ 84,872 $ 93,243
( )
1.
1051231 1041231
$ - $ 250
$ - $ 3,500
$ 65,393 $ 44,267
35 -
$ 65,428 $ 44,267
2.
105 104
$ 2,967 $ 3,207
600 600
$ 3,567 $ 3,807
$ 13,967 $ 16,344
3.
1051231 1041231
$ 3,297 $ 4,356
4.
1051231 1041231
$ 47 $ 73
5.
106
12
105 104
$ 4,296 $ 3,972
126
-
6. 105 104
105 104
$ 74,904 $ 749 $ 64,785 $ 654
( )
105 104
$ 36,817 $ 33,279 513 432 $ 37,330 $ 33,711
1051231 1041231
$ 505,197 $ 511,077
( ) 105 12 31
840,232
( ) 107
7 297
1051231 1041231
1 $ 943 $ 4,702 15 449 1,403 $ 1,392 $ 6,105
127
-
( )
301,999
158,335 102 10
17 31
105 8 24
110
1051231
$ 398 33.900 $ 13,492 389 32.250 12,545 384 22.400 8,602 3,348
0.668 2,238 335 4.158 1,393 152 4.617 702
90 32.250 2,894 58,927 32.250 1,900,410 1,410 22.400 31,593
6,351 33.900 215,299 850 22.400 19,040 208 0.668 139
4 32.250 129
128
-
104 12 31
$ 33 35.880 $ 1,184 182 32.825 5,974 441 22.500 9,923 2,577
0.717 1,848 1,677 4.235 7,102
138 4.995 689 474 32.825 15,559 49,940 32.825 1,639,295 1,559
22.500 35,084
6,360 35.880 228,197
1,541 22.500 34,673 73,315 0.273 19,993 578 0.717 415 11 32.825
361
105 22,489 104
26,942
( ) ( )
1.
2.
3.
4. 3
20%
5. 3 20%
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