DAFTAR ISI

Halaman Judul........................................................................................................i

Halaman Pengesahan ............................................................................................ii

Lembar Pernyataan..............................................................................................iii

Abstrak...................................................................................................................iv

Kata Pengantar.....................................................................................................vi

Daftar Isi................................................................................................................ix

Daftar Gambar.......................................................................................................x

Daftar Bagan.......................................................................................................xiii

Daftar Singkatan.................................................................................................xiv

Daftar Tabel..........................................................................................................xv

Daftar Lampiran.................................................................................................xvi

BAB 1. PENDAHULUAN

A. Latar Belakang ...................................................................1

B. Rumusan Masalah ...............................................................3

C. Tujuan Penelitian ................................................................4

D. Manfaat Penelitian .............................................................6

E. Keaslian Penelitian...............................................................6

BAB II. TINJAUAN PUSTAKA

A. Telaah Pustaka ....................................................................9

1. Definisi Ulkus Kaki Diabetik ........................................9

2. Klasifikasi Ulkus Kaki Diabetik ..................................9

3. Etiologi Ulkus Kaki Diabetik ......................................11

4. Faktor Resiko Ulkus Kaki Diabetik ...........................12

5. Patogenesis Ulkus Kaki Diabetik ...............................18

6. Manajen Penanganan Ulkus Kaki Diabetik ...............21

7. Kerangka Teori ............................................................28

8. Kerangka Konsep.........................................................29

B. Landasan Teori...................................................................30

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C. Hipotesis.............................................................................31

BAB III. METODE PENELITIAN

A. Desain Penelitian................................................................33

B. Lokasi dan Waktu Penelitian ............................................33

1. Lokasi Penelitian..........................................................33

2. Waktu Penelitian..........................................................33

C. Populasi dan Sampel Penelitian..........................................34

1. Populasi Target.............................................................34

2. Populasi Terjangkau.....................................................34

D. Sampel dan Teknik Sampling ……......…………..............34

E. Kriteria Restriksi.................................................................36

F. Variabel Penelitian..............................................................36

G. Definisi Operasional...... ....................................................36

H. Teknik Pengumpulan data..................................................40

1. Sumber data..................................................................40

2. Alat dan Bahan.. ..........................................................41

3. Langkah Kerja .............................................................41

I. Pengelolaan Data................................................................44

J. Teknik Analisa Data...........................................................44

1. Analisis Univariat.........................................................44

2. Analisis Bivariat...........................................................45

3. Analisis Multivariat......................................................46

BAB IV. HASIL PENELITIAN DAN PEMBAHASAN

A. Hasil Penelitian..................................................................47

1. Gambaran Umum Lokasi Penelitian..............................47

2. Karakteristik Umum Responden....................................48

3. Hasil Analisis Univariat.................................................53

4. Hasil Analisis Bivariat...................................................60

5. Hasil Analisis Multivariat..............................................66

B. Pembahasan

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1. Hubungan antara Usia dengan Kejadian Ulkus Kaki

Diabetik (UKD) ............................................................69

2. Hubungan antara Lama Menderita DM dengan Kejadian

Ulkus Kaki Diabetik (UKD) .........................................70

3. Hubungan antara Hipertensi dengan Kejadian Ulkus

Kaki Diabetik (UKD) ..................................................72

4. Hubungan antara Hiperglikemia dengan Kejadian Ulkus

Kaki Diabetik (UKD) ..................................................73

5. Hubungan antara Obesitas dengan Kejadian Ulkus Kaki

Diabetik (UKD) ............................................................75

6. Hubungan antara Merokok dengan Kejadian Ulkus Kaki

Diabetik (UKD) ............................................................78

BAB V. KESIMPULAN DAN SARAN

A. Kesimpulan........................................................................79

B. Saran ..................................................................................81

DAFTAR PUSTAKA...............................................................................84

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DAFTAR GAMBAR

Gambar 2.1 Kaki Diabetik Klasifikasi Wagner ...................................11

Gambar 3.1 Posisi Tubuh Respon Ketika Pengukuran ........................43

Gambar 4.1 Karakteristik Responden Penelitian Berdasarkan Kelompok

Usia....................................................................................49

Gambar 4.2 Karakteristik Responden Penelitian Berdasarkan

Jenis Kelamin.....................................................................50

Gambar 4.3 Karakteristik Responden Penelitian Berdasarkan

Pendidikan Terakhir...........................................................50

Gambar 4.4 Karakteristik Responden Penelitian

Berdasarkan Pekerjaan.......................................................51

Gambar 4.5 Distribusi Faktor Risiko UKD Berdasarkan

Umur Pada Sampel Penelitian............................................52

Gambar 4.6 Distribusi Faktor Risiko UKD Berdasarkan

Lama Menderita DM Pada Sampel Penelitian...................53

Gambar 4.7 Distribusi Faktor Risiko UKD Berdasarkan Riwayat

Hipertensi Pada Sampel Penelitian....................................53

Gambar 4.8 Distribusi Faktor Risiko UKD berdasarkan

hiperglikemia pada sampel penelitian...............................54

Gambar 4.9 Distribusi Faktor Risiko UKD Berdasarkan Obesitas

Pada Sampel Penelitian.....................................................55

Gambar 4.10 Distribusi Faktor Risiko UKD Berdasarkan

Riwayat Merokok Pada Sampel Penelitian........................55

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DAFTAR BAGAN

Bagian 1. Patofisiologi UKD..........................................................................18

Bagian 1. Kerangka Teori...............................................................................27

Bagian 2. Kerangka Konsep...........................................................................28

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DAFTAR SINGKATAN

AGE Advance Glycosilation Endproducts

ATP Adenosin Triphosphate

BB Berat Badan

BRFSS Behavioral Risk Factor Surveillance System

DM Diabetes Mellitus

DNA Deoxyribonucleic Acid

HDL High Density Lipoprotein

IMT Indeks Massa Tubuh

K Kalium

LDL Low Density Lipoprotein

Na Natrium

NO Nitric Oxide

Perkeni Perkumpulan Endokrinologi Indonesia

Riskesda Riset Kesehatan Dasar

RSU Rumah Sakit Umum

TB Tinggi Badan

TCC Total Contact Cast

TcPO2 Trans cutaneus Oxygen Tension

UKD Ulkus Kaki Diabetik

WHO World Health Organization

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DAFTAR TABEL

Tabel 2.1 Kadar Lipid serum normal NCEP- Adult Treatment

Panel (ATP) III...............................................................................15

Tabel 4.1 Distribusi Faktor Risiko UKD Berdasarkan Hiperlipidemia

Pada Sampel Penelitian..................................................................59

Tabel 4.2 Hubungan Usia Dengan Kejadian UKD

Pada Pasien DM.............................................................................60

Tabel 4.3 Hubungan Lama Menderita DM Dengan Kejadian

UKD Pada Pasien DM...................................................................61

Tabel 4.4 Hubungan Hipertensi Dengan Kejadian UKD

Pada Pasien DM.............................................................................62

Tabel 4.5 Hubungan Hiperglikemia Dengan Kejadian UKD

Pada Pasien DM.............................................................................63

Tabel 4.6 Hubungan Obesitas Dengan Kejadian UKD

Pada Pasien DM.............................................................................64

Tabel 4.7 Hubungan Merokok Dengan Kejadian UKD

Pada Pasien DM.............................................................................65

Tabel 4.8 Hasil Uji Regresi Logistik Ganda..................................................66

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DAFTAR LAMPIRAN

Lampiran 1 Lembar Persetujuan, Informed Consent, dan Kuesioner.

Lampiran 2 Surat Izin Penelitian

Lampiran 3 Surat Keterangan Telah Menyelesaikan Penelitian

Lampiran 4 Master Data Hasil Penelitian

Lampiran 5 Hasil Analisis Univariat Variabel Bebas Terhadap Ulkus Kaki Diabetik Responden

Lampiran 6 Hasil Analisis Bivariat Variabel Bebas Terhadap Ulkus Kaki Diabetik Responden dengan Menggunakan Uji Chi-Square Pada Program SPSS

Lampiran 7 Hasil Analisis Multivariat Beberapa Variabel yang Berhubungan dengan Ulkus Kaki Diabetik dengan Menggunakan Regresi Logistik Berganda Metode Backward Wald pada Program SPSS

Lampiran 8 Dokumentasi Penelitian

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