rtsi't

.!,

3504

mengkonsumsi vitamin D 1000 lU perhari. Pasien yangmenerima terapi penitoin jangka lama harus diberikanvitamin D 50.000 lU tiap 2 hingga 4 minggu untukprofilaktif.l3

PROGNOSIS

Kekurangan vitamin D akibat kurangnya asupan ataumalabsorpsi biasanya berespon dengan baik dengan terapipengganti vitamin D. Osteomalasia yang terkait dengangagal ginjal kronik sulit untuk dikelola dan memerlukanterapi jangka panjang. Sebagian kasus hipokalsemia terkaitgagal ginjal kronik, kadang sulit untuk diperbaiki.

REFERENSI

Lips, P.,vanSchoor, N.M., Bravenboer, N., Vitamin D-relateddisorders. In: Rosen, C.I., (Ed), Primer on the metabolicbone diseases and disorders of mineral metabolism 7fr ed.,American Society of Bone and Mineral Researclr, 2008. p.329-5Basha, B., Rao, D.S.,HNr,Z.H.,Par{itt, A.M. Osteomalacia dueto vitamin D depletion: a neglected consequence of intestinalmalabsorption. Am ] Med 2000;108:296-300.Kennel, K.A., Drake, M.T., Hurley, D.L., Vitamin D deficiencyin adults: when to test and how to treat. Mayo Clin Proc.2010;85:752-7.Cardinal, R.N. & Gregory, C.A., Osteomalacia and vitamin Ddeficiency in a psychiatric rehabilitation unit: case report andsurvey, BMC Research Notes, 2:82,1.-7,2009.Alleru S.C., Raut, S., Biochemical recovery time scales inelderly patients with osteomalacia. I R Soc Med, 2004;97:527-30.Lane, N.E., Metabolic Bone Disease. in: Firestein, G.S., Budd,R.C., Harris, T., Mclnnes, I.8., Ruddy, S., Sergen! G.S., eds.Kelley's Textbook of Rheumatology, 8th ed. Philadelphia:W.B. Sounders Company ; 2008.p. 1590-2.Al-Shoha, A., Qiu, S., Palnitkar, S., Rao, D.S., Osteomalaciawith bone marrow fibrosis due to severe vitamin D deficiency#ter a gastrointestinal bypass operation for severe obesify.Endocr Pract. 2009 ; 15:528-533.Bhambri, R., Naik, V., Malhotra, N., Taneja, S., Rastogi, S.,Ravishanker, U., Mithal, A., Changes inbone mineral densityfollowing treatment of osteomalacia. J Clin Densitom. 2006;9:\20-7.Drenzer, M.K., Osteomalacia and Rikets, in: Goldman, L.,Ausiello, D., eds. Goldman: Cecil Medicine,'2i'd ed' Chapter265. Philadelphia: Saunders Elsevier;2007. p. 1391-8Bringhurst, F.R., Demay, W.8., Krano, S.M., Kronenberg,H.M., Bone Structure and Metabolism. in: Fauci, A.S.,Braunwald, E., Kasper, D.L., Hauser, S.L., Longo, D.L.,Jameson, J.L., Loscalzo, f., eds. Harrison's Principles ofInternal Medicine 17s edition. New York : McGraw-HillCompanies; 2008. p. 2375-77Lang, F., Kidney, Salt and Water Balance: Pathophysiologyof Bone. in: Silbemagl, S.,LangF. eds. Color Atlas of Patho-physiology, Chapter 5. New York: Thieme;2000. p. 132-33.Marshall, T., Marshall, A.T., Bearcroft, P.W.B., Crisp, A.j.,Imaging in metabolic bone disease. in: Isenberg D.A., Peter,R., eds. Imaging in Rheumatology, 1"t EditiorL section.3:chapter 2L. London: Oxford University Press; 2003. p. 384-

PENYAKIT

400Cho, K.C., Endocrine Disorders: Introduction in McPbiS.J., Papadakis, M.A., eds. Current Medical Diagnm*Treatment, Chapter 26. Washington: McGraw-Hills; 2il;p.855-57.

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