Вакцинация против ящура и послевакцинационный мониторинг

Руководство

Редакторы: Самиа Метвалли, Сюзанна Мюнстерманн

Авторы: Джанкарло Феррари, Дэвид Пейтон, Серджо Дуффи, Крис Бартелс, Тео Найт-Джонс

ИзданоПродовольственной и сельскохозяйственной организацией Объединенных Наций

ии Всемирной организацией по охране здоровья животных

2020

Foot and mouth disease vaccination and post-vaccination monitoring

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1. Alexandersen S., Zhang Z., Donaldson A.I. & Garland A.J.M.(2003). – The pathogenesis and diagnosis of foot-and-mouth disease. J. comp. Pathol., 129, 1–36. doi: 10.1016/s0021- 9975(03)00041-0.

2. Armitage P. (1971). – Statistical methods in medical research.

3. Barnett P.V., Statham R.J., Vosloo W. & Haydon D.T. (2003).– Foot-and-mouth disease vaccine potency testing:determination and statistical validation of a model using aserological approach. Vaccine, 21, 3240–3248. doi: 10.1016/S0264-410X(03)00219-6.

4. Barteling S.J., Yadin H. & Sutmoller P. (2004). – Discussionpaper on guidelines for control of Foot-and-MouthDisease (FMD) vaccine quality and performance in the

commissions/docs/greece04/ App19.pdf.

5. Bennett S., Woods T., Liyanage W.M. & Smith D.L. (1991). – A

in developing countries. World Health Stat. Q., 44, 98–106.

competition ELISA to the measurement of anti-FMDV

immunization coverage: methods and processes. Bull. WorldHealth Organ., 87, 535–541. doi: 10.2471/BLT.08.053819.

in immunization programmes. Epidemiol. Rev., 18, 99–117.doi: 10.1093/oxfordjournals.epirev.a017931.

mass serology. J. virol. Methods, 107, 89–98. doi: 10.1016/S0166-0934(02)00196-9.

FMD vaccines. Vaccine, 17, 1767–1771. doi: 10.1016/j.vaccine.2009.08.039.

reproduction ratio and time-space analysis of a foot-and-mouth disease epidemic in Peru in 2004. Transbound. emerg.Dis., 55, 284–92. doi: 10.1111/j.1865-1682.2008.01023.x.

14. Fleiss J.L. (1981). – Statistical methods for rates and

16. Garland A.J. (1999). – Vital elements for the successful control Vaccine, 17,

1760– 1766.

virus. 3. Evaluation after infection and vaccination. Epidemiol.Infect., 99, 733–744. doi: 10.1017/ S0950268800066590.

IMA J. math. appl. Med. Biol., 14

19. Hayes R.J. & Bennett S. (1999). – Simple sample size calculation for cluster randomized trials. Int. J. Epidemiol., 28,319–326.doi:10.1093/ije/28.2.319.

to assess immunization coverage: a review of experience withBull. World Health Organ.,

60,253–260.

(53-55)

54

G. & Dekker A. (2008). – Foot-and-mouth disease vaccine

valency, fractionation method, and virus culture on thedose-response curve in cattle. Vaccine, 26, 6317–6321. doi:10.1016/j.vaccine.2008.09.021.

22. Jamal S.M., Shah S.I., Ali Q., Mehmood A., Afzal M. & Dekker A. (2013). – Proper quality control of formulated foot- and-mouth disease vaccines in countries with prophylactic vaccinationis necessary. Transbound. emerg. Dis., 61, 483–489. doi:

epidemic: stochastic dispersal in a heterogeneous landscape.Science, 294 (5543), 813–817. doi: 10.1126/science.1065973.

against foot-and-mouth disease. Br. vet. J., 151, 379–389. doi:10.1016/S0007-1935(95)80127-8.

Veterinary and human vaccine evaluation methods. Proc. biol.Sci., 281PMID: 24741009.

of foot-and-mouth disease vaccine effectiveness inTurkey. Vaccine, 32 (16), 1848–1855. doi: 10.1016/j.vaccine.2014.01.071.

immunity and coverage: modelling population protectionagainst foot-and-mouth disease in Turkishcattle. Sci. Rep., 6,22121. doi: 10.1038/srep22121.

Sessionofthe Research Groupofthe Standing Technical

protection from virus challenge for the assessment of thepotency of polyvalent aphtovirus vaccines in Argentina. Vaccine,26 (51), 6577–6586. doi: 10.1016/j.vaccine.2008.09.033.

Lamorde A.G. (1983). – The control of foot and mouth disease Rev. Sci. Tech. Off.

Int. Epiz., 2 (3), 771–780.

of calves to vaccination against foot and mouth disease. J. Hyg. (Camb.), 92, 105–116. doi: 10.1017/S0022172400064081.

Epidemiol.Rev., 10, 212–241.

V.M., Palma E.L. & Thomson G.R. (2005). – Selection of footand mouth disease vaccine strains – a review. Rev. Sci. Tech.Off. Int. Epiz., 24 (3), 981–93.

36. Pay T.W.F. & Hingley P.J. (1992). – Foot and mouth diseasevaccine potency tests in cattle: the interrelationship of

protection from challenge. Vaccine, 10, 699–706. doi:10.1016/0264-410X(92)90092-X.

assessment of foot-and-mouth disease vaccine potency and

neutralization tests. Vaccine, 28, 6235–6241. doi: 10.1016/j.vaccine.2010.07.012.

Vet. Rec., 170, 637–639. doi: 10.1136/vr.e4180.

Endurance of immunity against foot-and-mouth disease incattle after three consecutive annual vaccinations. Res. vet.Sci., 49, 236–242.

responses in Dutch cattle vaccinated with foot-and-mouth

Am. J. vet. Res.,30, 2125–2159.

test to evaluate immunity in potency tests of foot-and-mouthdisease vaccines. J. Immunol. Methods, 124, 111–119.

and mouth disease. Epidemiol. Infect., 116, 363–371. doi:10.1017/S0950268800052699.

animal health systems through improved control of major

of Diagnostic Tests and Vaccines for Terrestrial Animals, 2014.

www.oie.int/manual-of-diagnostic-tests-and-vaccines-for- terrestrial-animals/.

terrestrial-code/.

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978-92-5-131765-5 978-92-95115-27-9

I5975RU/1/11.19

ISBN 978-92-5-131765-5

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