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Iwatsuki Minami Hospital A case of no-reflow phenomenon during PCI to LIMA graft Iwatsuki-Minami hospital, Saitama, Japan Koichi Sano , Masaki Tsukagoshi, Yasunari Ueno, Seiichi Fukuda, Takayoshi Sato, Yasuyuki Maruyama

A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

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Page 1: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

A case of no-reflow phenomenon during PCI to LIMA graft

Iwatsuki-Minami hospital, Saitama, Japan

Koichi Sano, Masaki Tsukagoshi, Yasunari Ueno, Seiichi Fukuda, Takayoshi Sato, Yasuyuki, y , yMaruyama

Page 2: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

Medical history77 y.o. male

This patient was hospitalized by inferior AMI 12 yearsThis patient was hospitalized by inferior AMI 12 years

ago, and was performed CABG x3 (LIMA-LAD, SVG-

RCA, SVG-OM) because of his LM+multivessel disease.

He was referred to our hospital for the routine check-upHe was referred to our hospital for the routine check up.

Treadmill exercise test showed positive for ischemia

(Bruce 4min). Therefore, CAG was performed.CAG had been performed 1.5y ago in another hospital, and LIMA-

LAD didn’ have a significant stenosis.

Page 3: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

Risk factor□ Hypertension BP110/60, ARB, β-blocker

□ Hyperlipidemia LDL121mg/dl tocopherol nicotinate(+)

✔□ Hyperlipidemia LDL121mg/dl, tocopherol nicotinate(+)

□ Diabetes HbA1c 5.8%, voglibose(+)

□ F k✔

✔□ Former smoker 1pack x 40years

□ Family history father; heart disease(?)✔

E h di h

□ Others Cr1.5mg/dl, UA7.1mg/dl✔

EchocardiographyInferior wall: akinesis, LVDd/Ds 53/41, EF 45%e o a a es s, d/ s 53/ , 5%Moderate MR

Page 4: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

CAGCAG

RCA;RCA; Total occlusion

Page 5: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

CAGCAG

LCA;LCA; Total occlusion

Page 6: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

CAGCAG

SVG OM;SVG-OM; Patent

Page 7: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

CAGCAG

SVG RCA;SVG-RCA; Patent

Page 8: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

CAGCAG

LIMA LAD;LIMA-LAD; 75% stenosis x2

Page 9: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

CAGCAG

LIMA LAD;LIMA-LAD; 75% stenosis x2

Page 10: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

CAGCAG

LIMA LAD;LIMA-LAD; 75% stenosis x2

Page 11: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

CAG -summary-CAG -summary-CAG summaryCAG summary

12 years after CABG (LIMA-LAD, SVG-RCA, SVG-OM)y ( )

He was referred to our hospital for the routine check-up, not

b f ACSbecause of ACS.

Both of native right and left coronary arteries were occluded.

Both of 2 SVGs were patent, but LIMA-LAD had 2 stenoses.

Stenoses of LIMA were located at its body not at theStenoses of LIMA were located at its body, not at the

anastomosis.

PCI was performed 3 weeks after the CAG.

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Iwatsuki Minami Hospital

PCIPCI

LIMA-LAD; 75% stenosis x2

*PCI was performed ith 6F idi iwith 6Fr guiding via

his left radial artery.

Page 13: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

PCI-LIMAPCI-LIMA

Pre PCI IVUS;distal lesion

Lesion length: 19mmLesion length: 19mm

Page 14: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

PCI-LIMAPCI-LIMA

Pre PCI IVUS;prox lesion

Lesion length: 13mmLesion length: 13mm

Page 15: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami HospitalAttenuated plaque at LITA

PCIPCI Attenuated plaque was A

p qseen in prox and distal lesions.

BA

B

B

CB

C

C

C

Page 16: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

PCIPCI

POBA was performed without any distal protection deviceprotection device.The balloon was Sprinter 2.5x15mm.

Page 17: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

PCIH21.10.28

PCIH21.10.28H21.10.28H21.10.28

ST elevation in V3-6 with chest pain waswith chest pain was seen after balloon dilation.

Angiogram showed no-reflow phenomenonphenomenon.

Page 18: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

PCIPCINitroprusside 60 microgram was given super-selectively from very distal of LIMA graft d sta o g a tvia CrusadeTM (a multifunctional probing catheter)probing catheter).

ST level cameST level came back to the normal level, and hi h t ihis chest pain disappeared.

Page 19: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

PCIPCINitroprusside 60 microgram was given super-selectively from very distal of LIMA graft d sta o g a tvia CrusadeTM (a multifunctional probing catheter)probing catheter).

ST level cameST level came back to the normal level, and hi h t ihis chest pain disappeared.

Page 20: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

PCIPCINitroprusside 60 microgram was given super-selectively from very distal of LIMA graft d sta o g a tvia CrusadeTM (a multifunctional probing catheter)probing catheter).

ST level cameST level came back to the normal level, and hi h t ihis chest pain disappeared.

Page 21: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

PCIPCI

Taxus Liberte2 5 242.5x24mmMax14atm

Page 22: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

PCIPCI

Taxus Liberte2 75 162.75x16mmMax14atm

Page 23: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

PCIPCI

Final angiog

Next day;

CK188IU/l

No ECG change was

seen.

Page 24: A case of no-reflow phenomenon during PCI to LIMA graftsummitmd.com/pdf/pdf/1378_LITA-noreflow_English.pdf · no-reflow phenomenon. Iwatsuki Minami Hospital PCI Nitroprusside 60 microgram

Iwatsuki Minami Hospital

Summary

We have experienced a case of LIMA graft stenosisWe have experienced a case of LIMA graft stenosis

with attenuated plaque by IVUS, and no-reflow

phenomenon occurred during the PCI.

This case has shown the usefulness of IVUS guidedThis case has shown the usefulness of IVUS guided

PCI. We should be careful when we perform PCIs to the

lesions with attenuated plaque, and a distal protection

device must be considered.