ANGINA PECTORIS - JENNY NOVITA.pptx

8/18/2019 ANGINA PECTORIS - JENNY NOVITA.pptx

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FARMAKOTERAPI II

ANGINA PECTORIS JENNY NOVITA

1301043SI-VIA

SEKOLAH TINGGI ILMU FARMASI RIAUPEKAN BARU


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DEFENISIGangguan ang

!"#$u% a&"$a!'"()&*"a )!)!

+an!ung a!au n,"',$a! ang$,a*a% .a"

+an!ung .an !,+a."*,$aga" ,*()n

!,'a.a( *u(%a")&*"g,n ang !".a&a.,&ua! &, *,%-*,%

#")&a."u#/

An)n"#2004


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KLASIFIKASI

3 a"anu!a#aAng"na

P,&!)"*

Ang"naP,&!)"*!"("&a%*!a$"%

Ang"naP,&!)"*

Ta&S!a$"%

Ang"naP,&!)"*P"n5#,!

a%a"an


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B/ Ang"na (,6!)"* !".a& *!a$"%/

Ang"na ang $au (,!a#a &a%"a!au ang"na *!a$"% .,ngan&aa&!,"*!"& 7,&u,n*" $,a! .an

%a#ana #,n"ng&a!/ T"#$u% 8a&!u "*!"a'a!9&,+a

"ngan/ F"*"6a% a**,**#,n! !".a&

#,#$an!u/ EKG: D,"a*" *,g#,n! ST .,(,*"

a!au ,%,a*"/

KLASIFIKASI


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;/ Ang"na Va"an T,+a." a&"$a! a*)*(a*#,

6))n, *,angan n," !"#$u%*()n!an .a%a# &,a.aan "*!"a'a!.an &,$ana&an ."#a%a# 'a" .an

(ag" 'a"/ Va*)*(a*#a #,u(a&an

&,&,+angan ang ."*,$a$&an )%,'(,n,#("!an a!," &))na" .an$,&uangna a%"an .aa' &,

+an!ung/ Ang"na +,n"* "n" +aang!, a."/

KLASIFIKASI


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ETIOLOGI

Ang"na (,&!)"* .a(a! !,+a." $"%a )!)! +an!ung #,#,%u&ana*u(an )&*"g,n ang %,$"' (a.a 8a&!u !,!,n!u #"*a%na(a.a *aa! $,&,+a #a&an a!au *aa! *,.ang #,nga%a#"

*!,*/

Fa&!)- 7a&!) ang #,#(,ngau'"

(,#a&a"an )&*"g,n (a.a +an!ung

D,nu! Jan!ung

K)n!a&!"%"!a*

T,&ananS"*!)%"&

V,n!"&,%

K""

U&uan Jan!ung


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Da(a! D"u$a' ."#)."=&a*"a/ D",! '"(,%"(".,#"a$/ R)&)&6/ H"(,!,n*"./ S!,**,/ O$,*"!a*

7/ Kuang a&!"=!a*g/ D"a$,!,* M,%%"!u*'/ P,#a&a"an &)n!a*,(*" )a%

T".a& .a(a! ."u$a'

a/ U*"a$/ J,n"* K,%a#"n6/ Ra*./ H,,."!,

FAKTORPREDISPOSISI


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PATOFISIOLOGI

Penurunan suplaiO2 ke jantung ;peningkatankebutuan O2

jantung

Iske!ia "antung

"antungberusaa

!enggunakan

jalur lain n#n#ksigen untuk

tetap!en$apatkan

energi%!ekanis!e

anaer#b&

Mengasilkanpr#$uk sisa Asa! 'aktat

Peningkatan$erajat

keasa!an #t#t jantung

Angina Pe(t#ris%N)eri $a$a&


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PATOFISIOLOGI


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PATOFISIOLOGI

T


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Tan aGejala

+,Kepala seringpusing

2,-a$a terasasesak

.,Perut !ual$an ke!bung/,N)eri $i

bagian uluati

0,1erkeringat,1a$an terasa

$ingin

T


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Tan aGejala

Ang"na S!a$"% K)n"& Ang"na T".a& S!a$"% Ang"na Va"an

Mun6u% *aa! #,%a&u&ana&!"=!a* $,a!

T"#$u% 8a&!u "*!"a'a!9&,+a"ngan/ Ang"na ang !,+a." *()n!an

u#u#na 8a&!u "*!"a'a! .an(a.a 8a&!u a&!"=!a* "ngan/

B"a*ana !,+a." &a,na *(a*#,a!," &))n,H"%ang .a%a# 8a&!u (,n.,& ?@ #,n"!

T".a& .a(a! ."(,&"a&an$"a*ana %,$"' %a#a

H"%ang .,ngan *,g,a &,!"&aan.a $,"*!"a'a! a!au

#,ngguna&an (,ng)$a!an!,'a.a( ang"na

Da(a! !".a& a&an '"%ang *aa!$,"*!"a'a! a!au(un(,ng)$a!an ang"na EKG .,"a*" *,g#,n! ST

.,(,*" a!au ,%,a*" ang!"#$u% (a.a 8a&!u *,anganang &,#u."an n)#a% *,!,%a'*,angan *,%,*a"/

Da(a! ."("6u )%,' !,&anan#,n!a% a!au *!,*/

EKG: D,"a*" *,g#,n! ST.,(,*" a!au ,%,a*"/

3 K


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3ang K as arAngina

•

D"("6u )%,' a&!"=!a* =*"&• B,%ang*ung !".a& %,$"' .a"$,$,a(a #,n"!

•

A&an #,ng'"%ang +"&a (,n.,"!"*!"a'a!

• Ka.ang (,n.,"!a $"*a #,#(,."&*"

a&an !,+a." ang"na *,!,%a'#,%a&u&an &,g"a!an !,!,n!u


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-IAGNOSIS

P,#,"&*aanLa$)a!)"u#

Saa! *,angan ang"naEKG a&an #,nun+u&&ana.ana .,(,*" *,g#,n

ST .an g,%)#$ang T#,n+a." n,ga!"7/

*,"ng&a%" #,nun+u&&an

$,n!u& +an!ung angn)#a% !,!a(" (a.a

(a*",n '"(,!,n*" .a(a!!,%"'a! +an!ung ang

#,#$,*a .an &a.ang-&a.ang !a#(a& a.ana&a%*"=&a*" a&u* a)!a/

Un!u& #,n"ng&"&an ."agn)*"*"n7a& #")&a. (,#,"&*aan,n5"# ;PK SGOT a!au LDH ,n5"# !"ngg" $"%a "n7a& n)#a%

$"%a ang"na

E%,&!)&a.")ga# EKG

F)!) R)n!g,nDa.a


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-IAGNOSIS

U+" La!"'an Ja*#an"

D"$ua! EKG (a.a 8a&!u "*!"a'a! %a%u

(a*",n ."*uu' #,%a&u&an %a!"'an.,ngan a%a! !,a.#"%% a!au *,(,.a

,g)#,!, *a#(a" (a*",n #,n6a(a"&,6,(a!an +an!ung #a&*"#a% a!au

*u$#a&*"#a% .an *,%a#a %a!"'an EKG ."#)n"!) .,#"&"an (u%a *,!,%a' *,%,*a"

EKG !,u* ." #)n"!)/ T,* ."angga(()*"!"7 $"%a .".a(a!&an .,(,*" *,g#,n

ST *,$,*a 1 ## a!au %,$"' (a.a 8a&!u%a!"'an a!au *,*u.a'na/ T'a%%"u# 201 ."*un!"&&an *,6aa

"n!a,na (a.a (un6a& %a!"'an &,#u."an."%a&u&an (,#,"&*aan *6ann"ng +an!ung

*,g,a *,!,%a' %a!"'an ."',n!"&an .an."u%ang &,#$a%" *,!,%a' (a*",n *,'a! .an&,#$a%" n)#a%/ B"%a a.a "*&,#"a #a&a

a&an !a#(a& 6)%. *()! (a.a .a,a' angang #,n.,"!a "*&,#"a (a.a 8a&!u%a!"'an .an #,n+a." n)#a% *,!,%a'

(a*",n "*!"a'a!/

T'a%%"u#

E,6"*,M)6a."a%

I#ag"ng

PENATA'AKSANAAN


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PENATA'AKSANAAN

TerapiFar!ak#l#gi

NITRAT ORGANIK N"!a! )gan"& #,nuun&an &,+a +an!ung #,%a%u" ,7,&."%a!a*" (,#$u%u' .aa' *"*!,#"& #,n,$a$&an (,nuunan,*"*!,n*" (,"7, *,'"ngga !,gangan ."n."ng ,n!"&,%*,8a&!u *"*!)%, $,$an '"%" $,&uang/ A&"$a!na &,+a +an!ung .an &)n*u#*" )&*"g,n #,n+a." $,&uang/

P,#$,"an .)*"*: @-10 #6g9#,n"! IV #,%a%u" "n7u* *,!,%a'."%u*"/PENG4AM1AT A-RENOSEPTOR 1ETA %561'OCKER&M,nguang" &,$u!u'an )&*"g,n +an!ung .,ngan 6aa#,nguang" .,nu! +an!ung .an &)n!a&!"%"!a* #")&a./;)n!)' : P)(an)%)% a*,$u!)% #,!)()%)% a!,n)%)%

PENG4AM1AT KANA' Ca77

M,%,$a&an (,#$u%u' .aa' .,ngan #,ng'a#$a!#a*u&na ")n &a%*"u# #,%,8a!" *%)8 6'ann,% ang!,.a(a! (a.a #,#$an *,% *a&)%,#a (a.a )!)! ()%)* +an!ung .an (,#$u%u' .aa' &))n, .an (,"7, *,'"ngga!,+a."na ,%a&*a*"/;)n!)' : A#%)."("n, ."%!"a5,# n"7,."("n,

PENATA'AKSANAAN


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PENATA'AKSANAAN

Terapi N#n6

Far!ak#l#gi1/ B,',n!" #,)&)&2/ M,#$a!a*" #"nu# &)(" .an a%6)')%3/ M,ng'"n.a" $,$an $,a! #,n!a% #au(un =*"&4/ B,+a%an 0@ 1 +a# *,'a" a!au 3-@ &a%" *,#"nggu@/ M,ng)$a!" '"(,!,n*" $"%a a.a &a,na TD #,#(,$uu&

&,a.aan (,#$u%u' .aa'

Pa*",n .,ngan ang"na !".a& *!a$"% .an (a*",n .,ngan()*!-"n7a& #")&a. .,ngan %an+u!an ang"na a!au "*&,#"&%,$"' (aa' .a(a! ."%a&u&an ,a*&u%a"*a*" ang ."%a&u&an.,ngan ()*,.u ang ."*,$u! 6))na a!, $(a**ga7!"ng ;ABG .an (,6u!an,)u* !an*%u#"na% 6))naang")(%a*! PT;A/

" & " ' % ."


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M AG *,)ang *)(" !a&*" @< !a'un a*a% In."a#,ng'a."" An.a a()!,& #a*aa&a! .,ngan ,*,($au un!u&: g%"*,"% !"n"!a! GTN *,#()! 400#"&)ga# - *a!u a!au .ua "*a(an ang ."(,%u&an/An.a #,ng,%ua&an "!,# "n" .an $,$"6aa .,ngan."a .an ."a #,#$,"!a'u An.a $a'8a GP na$,("&" "a #,#"%"&" ang"na .an !,%a' #,#"n!a ."aun!u& #,ngguna&an *,#()!an 8a&!u $,"&u!na "a

#,n.a(a! *a&"! .a.a &,6"% a!au *,*a&/ An.a#,na*"'a!" M AG (a.a (,nggunaan ang $,na.a" *,#()!an/M AG &,#$a%" $,$,a(a 'a" &,#u."an #,ng,%u'

*a&"! &,(a%a *,!,%a' (,nggunaan *,#()!an/ D"a,nggan un!u& #,ngguna&an *,#()!an %ag"/ D"a#,#"n!a *aan An.a (a.a (,ng,%)%aan *a&"!&,(a%ana/ D"a +uga #,)&)& *,&"!a %"#a $a!ang)&)& *,#"nggu .an $,!ana a(a&a' "a *,&aang

'au* $,',n!"/

KASUS


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•-M,#$a!a*" #"nu# a%&)')%

.an &)("•-M,ng'"n.a" $,$an $,a!#,n!a% *!,** ,#)*"#au(un =*"& !,u!a#a*,!,%a' #a&an a!au #an." a"'anga!•

-B,+a%an 0@- 1 +a# *,'a"a!au 3-@ &a%" *,#"nggu *,6aa$,!,naga aga& 6,(a! a!au$,%a"-%a" *an!a" guna#,#(,$a"&" *"&u%a*" +an!ung

Plan T,a(" ang a&an ."$,"&an

&,(a.a M/AG

• M,#$,"&an (,ngaa'an!,n!ang ang"na .an (,n!"ngna(,ng)$a!anna•

M,n+,%a*&an ,7,& *a#("ng.a" n"!)g%"*,"n !,*,$u!• S(a GTN 400 #"&)ga#."*aan&an !".a& %,$"' .a" !"ga.)*"* .a%a# 1@ #,n"! $"%a!,+a." *,*a&/

• M,#"nu# (aa6,!a#)% @00#g 4 &a%" *,'a" *,!"a( +a#• J"&a *a&"! &,(a%a $,%an+u!&)n*u%!a*"&an &,(a.a GP-na• Tn/AG ."*aan&an un!u&$,',n!" #,)&)& aga !".a&

#,#(,(aa' (,na&"! ang"naang .".,"!ana/


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Pen(egaan1/ P,u$a'an (a.a .",!Ka+"an #,nun+u&&an $a'8a #a&anan ang !"ngg" &an.ungan

&)%,*!,)% .an %,#a&na $"*a #,n"ng&a!&an &)%,*!,)% .a%a#.aa' a&an #,n"ng&a!&an ,*"&) un!u& #,ng".a( (,na&"!&))na"

2/ S,na#•

Ka+"an #,nun+u&&an $a'8a #,,&a ang !".a& $,*,na#6,n.ung un!u& #,n.a(a!&an *,angan +an!ung/• Ja."&an *,na# *,$aga" .a" gaa '".u(

3/ Pan!au !,&anan .aa' T,&anan .aa' !"ngg" #,n"ng&a!&an ,*"&) *,angan +an!ung/ 4/ Jaga $,a! $a.anP,na&"! !,u!a#a ."a$,!,* !,&anan .aa' !"ngg" .an (,na&"! +an!ung &))na" $"*a #,n,ang .,ngan #u.a' (a.a "n."".uang #,nga%a#" $,a! $a.an ang $,%,$"'an /


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ANGINA PECTORIS - JENNY NOVITA.pptx