List of Auto AntibodiesAntibody Disease Prevalence (%)Anti-dsDNA SLE 70Anti-nuclear Antibodies SLE

Systemic Sclerosis (SS)Sjogren’sPolymyositisDermatomyositisRAJIAAutoimmune hepatitisDrug-induced lupusMyasthenia gravisIdiopathic Pulmonary FibrosisDiabetes mellitusInfective mononucleosisNormal pop

957080404030Variable100>955030255-108

Anti-histone Drug induced lupus -Anti-centromeric Limited SS 70Anti-Ro (SS-A) SLE

Sjogrens40-6060-90

Anti-La (SS-B) SLESjogren’s

1535-85

Anti-Sm SLE 10-25 (Caucasian)30-50 (Black African)

Anti-UI-RNP SLEOverlap syndrome

30

Anti-JO (anti-synthetase) PolymyositisDermatomyositis

30

Anti-CCP Rheumatoid arthritisAnti-topoisomerase 1 (Scl-70) Diffuse cutaneous SS 30ANCA (anti-neutrophil cytoplasmic antibodies)

Vasculitis (esp small vessel):-Microscopic polyangiitis-Wegeners granulomatosis-Churg Strauss syndrome

90%

Anti-acetylcholine receptor Myasthenia gravisAnti-mitochondrial Primary biliary sclerosisAnti-GBM Goodpasture’s syndrome