Chapter 9Chapter 9 herbs that herbs that tonifytonify 补虚药补虚药

introductionintroduction Concept Herbs: Can enhance Concept Herbs: Can enhance

body energy, improve to anti-body energy, improve to anti-disease. disease.

Tonity QI, blood Ying & Yang Tonity QI, blood Ying & Yang four categories.four categories.

Herbs Tonify Main effects:Herbs Tonify Main effects:

1 immunity function1 immunity function

can enhance body immunity, anti can enhance body immunity, anti cancer & diseases, anti-infectious cancer & diseases, anti-infectious diseasesdiseases

Enhance non-specific immune Enhance non-specific immune functionfunction

enhance body immune organs enhance body immune organs thymus, spleen weight.thymus, spleen weight.

a. Enhance macrophage phagocytosisa. Enhance macrophage phagocytosis

b. Raise white cell numbersb. Raise white cell numbers

Enhance cellular immunity Enhance cellular immunity

functionfunction

①① Raise lymphyocyte in spleenRaise lymphyocyte in spleen

②② Enhance lymphyocytes combination Enhance lymphyocytes combination

raterate

③③ Enhance red cell immunityEnhance red cell immunity

Enhance humoral immunity Enhance humoral immunity

①① Raise antibody developmentRaise antibody development

②② Raise anti-body produce cell in spleenRaise anti-body produce cell in spleen

2 CNS effects2 CNS effects

enhance brain memory, make enhance brain memory, make you smartyou smart

3 metabolism effects3 metabolism effects

tonify nutritiontonify nutrition ①① Help nucleotide and amino acid Help nucleotide and amino acid

synthesissynthesis

②② Faty and glucose metablismFaty and glucose metablism

③③ Mineral metablismMineral metablism

④④ Adjust Adjust cyclic nucleotide

4 endocrine effects4 endocrine effects

enhance hypathalamus-pitutary enhance hypathalamus-pitutary gland-adrenal cotex axis gland-adrenal cotex axis functionfunction

enhance hypathalamus-pitutary enhance hypathalamus-pitutary gland-sexual gland functiongland-sexual gland function

regulate hypathalamus-pitutary regulate hypathalamus-pitutary gland-sexual-thyroid functiongland-sexual-thyroid function

5 anti-age5 anti-age

6 enhance organ or system 6 enhance organ or system functionsfunctions

hemopoietic system

①① Rise red blood cell &HBRise red blood cell &HB

②② increase platelet numberincrease platelet number

③③ Rise WBCRise WBC

7 anti-cancer7 anti-cancer

RensenRensen 人参人参 components:components: volatile oilvolatile oilsaponins know as panaxosides saponins know as panaxosides or ginsenosidesor ginsenosidesantioxidantsantioxidantspeptidespeptidespolysacchridespolysacchridesfaty acids.faty acids.

IndicationsArrythmia: for atrial fibrillation, sick sinussyndrome, ventricular arrhythmiaAngina pectorisLeukopeniaHepatitisCancerDiabetesProlonged life

1 main effects1 main effects （（ 11 ）） CNS effectsCNS effects

it has a stimulating effects in low it has a stimulating effects in low doses, but an inhibiting effect in doses, but an inhibiting effect in large doses. It increases the large doses. It increases the amounts of dopamine & amounts of dopamine & norrepinephyrine in the brain norrepinephyrine in the brain stem.stem.

Cognitive: improve memory & Cognitive: improve memory & learning abilitylearning ability ：：①① Enhance RNAEnhance RNA & protein synthesize & protein synthesize

in brainin brain

②② Enhance Nerve Ach synthesis & Enhance Nerve Ach synthesis & releasingreleasing ，， & rise DA& rise DA & NA in brain& NA in brain

③③ Enhance brain cell Enhance brain cell developmentdevelopment ，， rise brain weight, rise brain weight, enhance brain neuron functionenhance brain neuron function

④④ Protect nerve cell, enhance N cell Protect nerve cell, enhance N cell lifelife

⑤⑤ Enhance oxygen & blood supplyEnhance oxygen & blood supply

（（ 22 ）） immuno stimulantimmuno stimulant

enhance rat spleen NK cell enhance rat spleen NK cell

activityactivity ， ， induce induce γγ-IFN-IFN & IL-2& IL-2 。。 （（ 33 ）） enhance enhance hemopoietic system

人参 人参 can stimulate bone can stimulate bone

marrow, make RBC marrow, make RBC ，， promote promote

DNADNA 、、 RNA & protein RNA & protein

synthesis in bone marrow---synthesis in bone marrow---

rise RBCrise RBC

（（ 44 ）） endocrine effectsendocrine effects It can stimulate pituitary gland to It can stimulate pituitary gland to

increase the secretion of ACTH.increase the secretion of ACTH. enhance Hypothlamus-pitutary—enhance Hypothlamus-pitutary—

adrenal adrenal Enhance hypothlamus-pitutary- sexual Enhance hypothlamus-pitutary- sexual

gland functiongland function Enhance thyroid in rabbit.Enhance thyroid in rabbit.

（（ 55 ）） metabolism effectsmetabolism effects Enhance nucleotide & protein synthesis.Enhance nucleotide & protein synthesis. hypoglycemichypoglycemic Low blood sugarLow blood sugar

（（ 66 ）） cardiac effectscardiac effectsEnhance cardiac Enhance cardiac

contractioncontractionRelax vessel , adjust BPRelax vessel , adjust BPAnti-shock Anti-shock Anti-ischemic Anti-ischemic

（（ 77 ）） anti-ageanti-age

①① RenshengRensheng 人参皂苷 人参皂苷 inhibit inhibit old rat enzyme activity.old rat enzyme activity.

②② RenshengRensheng 人参 人参 increase SOD increase SOD ( superoxide dismutase), ( superoxide dismutase), clear free radicals, protect clear free radicals, protect cell membrane.cell membrane.

③③ RenshengRensheng 人参皂苷人参皂苷 Rg1 anti Rg1 anti Nerve cell membrane age.Nerve cell membrane age.

（（ 99 ）） anti-canceranti-cancer

2 other effects2 other effects

Protect liver Protect liver

anti-ulcer & inflammation.anti-ulcer & inflammation.

Reproductive effectsReproductive effects

【【 side effectsside effects 】】

1.1. It could cause eruption, It could cause eruption,

itching, headache, dizziness, itching, headache, dizziness,

& body temperature & body temperature

increase as well as bleeding. increase as well as bleeding.

2.2. It is prohibited in excessive It is prohibited in excessive

syndromes, & damp-heat syndromes, & damp-heat

syndromes.syndromes.

Huang qi Huang qi 黄芪黄芪 it is sweet, slightly warm. Enter it is sweet, slightly warm. Enter lung & spleen. Tonify Qi & stablize lung & spleen. Tonify Qi & stablize exterior, promote urination & exterior, promote urination & reduce edema, promote the reduce edema, promote the discharge of pus & generate the discharge of pus & generate the flesh.flesh.

Components: Components: carbohydrates of carbohydrates of astragalusastragalus Glycoside Glycoside Alkaloids Alkaloids Amino acids et al Amino acids et al

1 Main effects1 Main effects （（ 11 ）） enhance immunity functionenhance immunity function

Enhance function T lymphocytesEnhance function T lymphocytes Produce IgG, IgAProduce IgG, IgA

（（ 22 ）） enhance hemopoietic enhance hemopoietic

functionfunction promote hematopoietic functionpromote hematopoietic function It can increase RBC &WBC by stimulating It can increase RBC &WBC by stimulating

the bone marrow.the bone marrow. Inhibit the aggregation of thrombocytes by Inhibit the aggregation of thrombocytes by

means of cAMP of thrombocyte.means of cAMP of thrombocyte.

（（ 33 ）） effects on substance effects on substance

metabolismmetabolism （（ 4 4 ）） anti-ageanti-age

1. Huangqi can prolong the animal 1. Huangqi can prolong the animal

cell’s life.cell’s life.

2. it can stimulate the function of 2. it can stimulate the function of

SOD (superoxide dismulase)SOD (superoxide dismulase)

3. it can increase catecholamine 3. it can increase catecholamine

(CA), it inhibits the activity of MAO-(CA), it inhibits the activity of MAO-

BB

4. it can decrease free radicals.4. it can decrease free radicals.

（（ 55 ）） cardiac effectscardiac effects Promote function of heartPromote function of heart low BPlow BP Anti Anti --Viral myocarditisViral myocarditis

（（ 66 ）） digestive systemdigestive system Protect liverProtect liver Anti-ulcerAnti-ulcer

【【 indicationsindications 】】

1.1. Common coldCommon cold

2.2. Viral myocarditisViral myocarditis

3.3. Coronary heart diseaseCoronary heart disease

Heart failureHeart failure

4.4. Chronic hepatitisChronic hepatitis

DangguiDanggui 当归当归

Components:Components:    ferulic acid, , succinic acid, succinic acid, polysaccharide, amino acid, many polysaccharide, amino acid, many vitaminsvitamins

1 Main effects1 Main effects

tonify blood & remove stasis, tonify blood & remove stasis,

warm meridian stop warm meridian stop

painpain ，， benefit to constipation.benefit to constipation. （（ 11 ）） enhance hematopoiesisenhance hematopoiesis （（ 22 ）） anti- thrombosisanti- thrombosis （（ 33 ）） anti-hyperlipaemiaanti-hyperlipaemia

（（ 44 ）） cardiac system effectscardiac system effects Anti-ischemic, anti-arrhythmia Anti-ischemic, anti-arrhythmia Relax vessels, low bpRelax vessels, low bp

（（ 55 ）） regulate vagina muscle regulate vagina muscle

functionfunction （（ 66 ）） enhance immunityenhance immunity

Nonspecific immunityNonspecific immunity Cellular immunityCellular immunity Humeral immunityHumeral immunity

2 other effects2 other effects （（ 11 ）） protect liver functionsprotect liver functions （（ 22 ）） anti-radiationanti-radiation (3) anti-free radical, anti (3) anti-free radical, anti

inflammationinflammation

【【 indicationsindications 】】

1.1. arrhythmiaarrhythmia

2.2. thromboangitis obliteransthromboangitis obliterans 血血栓闭塞性脉管炎栓闭塞性脉管炎

3.3. Woman healthWoman health

4.4. Pain caused by blood stasisPain caused by blood stasis

ShudihuangShudihuang 熟地黄熟地黄

Components:Components: glycosides, catalpinoside, glycosides, catalpinoside, rehmanninrehmannin

1 main effects1 main effects （（ 11 ）） enhance immunityenhance immunity （（ 22 ）） anti hyper thyroidanti hyper thyroid （（ 33 ）） low blood sugarlow blood sugar （（ 44 ）） enhance adhesive & enhance adhesive &

hematopoiesishematopoiesis （（ 55 ）） anti- lipid hydroperoxideanti- lipid hydroperoxide （（ 66 ）） Low BPLow BP

2 other effects2 other effects （（ 11 ）） anti-ulceranti-ulcer （（ 22 ）） inhibit endothelial inhibit endothelial

hyperplasiahyperplasia

【【 indicationsindications 】】

1.1. 银屑病 银屑病 PsoriasisPsoriasis

2.2. diabetesdiabetes

GouqiZi GouqiZi 枸杞子枸杞子

Components:Components:betainebetaine 、、 polysaccharidepolysaccharide 、、 escopoletin.escopoletin.

1 1 main effectsmain effects （（ 11 ）） enhance immunityenhance immunity （（ 22 ）） anti-ageanti-age （（ 33 ）） protect liverprotect liver （（ 44 ）） low blood sugarlow blood sugar

2 other effects2 other effects

（（ 11 ）） anti-canceranti-cancer

（（ 22 ）） low BPlow BP

【【 indicationsindications 】】1.1. Anti-age usingAnti-age using

2.2. Cancer supplement Cancer supplement treatmenttreatment

3.3. Low senior high cholesterol Low senior high cholesterol

4.4. DiabetesDiabetes

5.5. Man infertilityMan infertility

鹿茸鹿茸 amino acid.amino acid.

1 Main effects1 Main effects

Stronger YangStronger Yang ，， enhance essential enhance essential & bone& bone

（（ 11 ）） hormone like effectshormone like effects （（ 22 ）） RNS protein synthesisRNS protein synthesis （（ 33 ）） enhance bone growenhance bone grow （（ 44 ）） enhance hematopoiesisenhance hematopoiesis （（ 55 ）） immunityimmunity （（ 66 ）） anti-stressanti-stress （（ 77 ）） anti-ageanti-age

2 other effects2 other effects

（（ 11 ）） Cardiac effectsCardiac effects

（（ 22 ）） anti-inflammationanti-inflammation

（（ 33 ）） anti-ulceranti-ulcer

【【 indicationindication 】】

1.1. impotenceimpotence

2.2. Blood diseasesBlood diseases