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Titolo presentazione
sottotitolo
Milano, XX mese 20XX
Come la Ricerca diventa Innovazione
Exposanità, Bologna 19/05/2016
- Innovazione come risorsa per migliorare i risultati e razionalizzare i costi -
Paola Bagnoli e Roberto Tiezzi
Politecnico di Milano
Technology Transfer Office (TTO)
Cos’è un’innovazione?
“Innovation is executing new ideas to create value”
Cos’è un’innovazione?
“Innovation is executing new ideas to create value”
• Creatività Idea
• Idea Pianificazione
• Pianificazione Execution
• Execution Investimenti
• Investimenti Rischio
• Rischio Execution
Tutela dell’idea “Appropriazione”
Dalla ricerca all’innovazione
Strategia IP
Progettazione Tutela Exploitation Valutazione
• Ricerca di anteriorità
• Libertà di attuazione
• Quale lo strumento
più adatto?
Progetto di Ricerca
• Analisi strategiche
• Pianificazione
• Analisi prior art
• Analisi dei concorrenti
Exe
cu
tion
Quale lo strumento più
adatto?
• Brevetti per invenzione
• Modelli di utilità
• Marchi
• Disegni e modelli
• Know-how
Dalla ricerca all’innovazione
Strategia IP
Progettazione Tutela Exploitation Valutazione
Progetto di Ricerca
Exe
cu
tion
Quale lo strumento più
adatto?
• Brevetti per invenzione
• Modelli di utilità
• Marchi
• Disegni e modelli
• Know-how
Dalla ricerca all’innovazione
Strategia IP
Progettazione Tutela Exploitation Valutazione
Progetto di Ricerca
Exe
cu
tion
BENI IMMATERIALI
Come tutelare l’innovazione? Differenti tipologie di
Proprietà Industriale (IP)
know-how
disegno (forma
esteriore)
marchio (azienda, prodotto)
brevetti per invenzione
diritto d’autore
(Software)
La PI nel settore delle Biotecnologie e
Scienze della Vita in Italia
www.uibm.gov.it/biotech/home/
Banca dati Biotecnologie e Scienze della Vita
Fonte: Banca dati Biotecnologie e Scienze della Vita
Classificazione domande di brevetti BioMed depositate in Italia tra il 1/07/2008 e il 2015**
Fonte: Banca dati Biotecnologie e Scienze della Vita
N. domande di brevetto depositate in Italia
Life science
Biotecnologie
Numero di estensioni internazionali EP - PCT
Fonte: Banca dati Biotecnologie e Scienze della Vita
Life science
Biotecnologie
Il trasferimento tecnologico
Trasferimento tecnologico
Valorizzazione della ricerca
dalla ricerca alla Società
Attori del trasferimento: • Ricercatori • Università
• Uffici di trasferimento tecnologico (TTO)
• Spin-off
• Imprese
Mercato IMPATTO
IP
IMPATTO
Non solo numeri:
-n. brevetti
-n. licenze
-n. spin-off
Impatto socio-economico della
ricerca sulla società
Impatto economico ma non solo!
Impatto sulla vita delle
persone…
non è semplice da quantificare…
…e le tecnologie di nicchia?!
Cos’è un’innovazione?
“Innovation is executing new ideas to create value”
• Creatività Idea
• Idea Pianificazione
• Pianificazione Execution
• Execution Investimenti
• Investimenti Rischio
• Rischio Execution GENERARE IMPATTO
Cos’è un’innovazione?
“Innovation is executing new ideas to create value”
• Creatività Idea
• Idea Pianificazione
• Pianificazione Execution
• Execution Investimenti
• Investimenti Rischio
• Rischio Execution
• Scarsa pianificazione della
ricerca
• Chi genera l’invenzione non è
chi poi la produrrà
• Definizione dell’applicazione
target
• Scarsa apertura del mercato
• Scarsa predisposizione delle
imprese al rischio
PRINCIPALI
CRITICITA’
In ambito universitario Uffici Trasferimento Tecnologico
- Supporto al ricercatore:
• analisi prior art brevettuale
• assistenza tutela IP
• bandi e contratti di ricerca per lo sviluppo
- Identificazione del corretto target di applicazione e mercato:
• Valutazioni del mercato
- Assistenza nel passaggio da prototipo a prodotto
- Supporto creazione spin-off
- procedura di accreditamento
- incubazione e accelerazione
- supporto alla creazione del business plan
- contatti con investitori
- Licensing:
• scouting di aziende
• link tra ricerca e azienda
• assistenza nella stipula di contratti
Supporto al trasferimento tecnologico
Ricerca
Execution
Technology Transfer Function al
Politecnico di Milano
PoliMI TTO mission
To promote protection and exploitation of the University research
To play a role in the relationships between University and Industry
To make possible the industrial applications of innovation also through the
entrepreneurship promotion and support
To improve the excellence of the University,
To attract students and outstanding Scientists
To attract research funds from Companies
Research valorisation
Technology Transfer Business Units
Technology
Transfer
Office
Training Intellect. property
&
Licensing
IP within
research contracts
National & international
projects
Spin-off
creation Networking
Polimi patents
64 85 128 165 209
255 298
339 384 419
454 498
146 191
306
395
502
614
727
815
913
1011
1109
1216
0
200
400
600
800
1000
1200
1400
Dato
cumulato1998-
2004
2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
number of Patent Families
Numbers of Patents
Cumulative data
Spin-off companies
Politecnico di Milano has created 34 spin-off companies (27 still active as spin-
off) acting in different industrial sectors.
The other partners are professors of Politecnico, young graduates, in many cases industrial companies interested in cooperating and developing new
products.
Industrial
eng.
32%
Electronics
15% Services
7%
Automation
7%
Home
products
7%
ICT
32%
> 13.65 M€
Global Turnover 2014
T.I.Ve.T.
Politecnico spin-off companies: a channel for exploitation
Steriline Robotics
POLIHUB Startup District & Incubator
+ than 100 startups since 2000
+ than 80 millions euro turnover
generated during incubation
+ than 50 companies in 2014
83% operative companies
9th in the UBI-INDEX ranking of the
best European incubators
POLIHUB
is an initiative:
Polimi IP portfolio
Target Areas
These are areas of interests chosen with a human and industry need-based
approach. Each category is gathered by looking at the main advantage that our
technological solution brings in targeted sector.
Environment and Energy
Smart Products Life Science
Information & Communication
Technologies (ICT) Industrial Manufacturing
Micro & Nano Technologies
Number of IPRs vs. Target Area
10% Environment and Energy
Information &
Communication
Technologies (ICT)
Life Science
Micro & Nano
Technologies
Industrial
Manufacturing
Smart Products
7% 10%
23%
30%
16%
14%
2011-2015 IP Portfolio Analysis (235 IPRs)
Number of IPRs vs. Target Area
Environment
and Energy
7% 10% 23%
30%
16%
14%
2011-2015 IP Portfolio Analysis (235 IPRs)
ICT Industrial
Manufacturing
Smart
Products
Micro & Nano
Technologies
Life
Science
Autonomous
research
Industry funded
research
Number of IPRs vs. Technology keywords
These are significant keys to classify our IPRs by technological subject and application
field. The infographic shows the Technology Keywords related to the number of patents
represented by shade and size scale.
Heat Engines
Solar energy
Infrastructures
Management tools
Micro-fluid dynamics
Artificial neural
networks
Smart packaging
3D printing
Nanotechnologies
Wearable
Aerospace
Waste management
Chemical reactors Water, air and soil conservation
Fluid dynamics
Diagnostics
Industrial Plant Maintenance Design of machines
Cell culture
Chemical synthesis
Photonics
Micro & Nano Electronics
Smart building
Energy efficiency
Chemical process
Wellbeing and sport
Emission Reduction
Automotive
Industrial design
Smart Mobility
Medical
Devices
Human
Safety
Advanced Materials
Telecommunication
& Computer
Technologies
2011-2015 IP Portfolio Analysis (235 IPRs)
Number of IPRs vs. Technology keywords
Heat Engines
Solar energy
Infrastructures
Management tools
Micro-fluid dynamics
Artificial neural
networks
Smart packaging
3D printing
Nanotechnologies
Wearable
Aerospace
Waste management
Chemical reactors Water, air and soil conservation
Fluid dynamics
Diagnostics
Industrial Plant Maintenance Design of machines
Cell culture
Chemical synthesis
Photonics
Micro & Nano Electronics
Smart building
Energy efficiency
Chemical process
Wellbeing and sport
Emission Reduction
Automotive
Industrial design
Smart Mobility
Medical
Devices
Human
Safety
Advanced Materials
Telecommunication
& Computer
Technologies
2011-2015 IP Portfolio Analysis (235 IPRs)
These are significant keys to classify our IPRs by technological subject and application
field. The infographic shows the Technology Keywords related to the number of patents
represented by shade and size scale.
Life science: alcuni casi interessanti
Dispositivo per l’addestramento chirurgico
della litotrissia percutanea (PCNL)
PCNL Tecnica usata per la rimozione dei calcoli renali
Fantoccio per training dei chirurghi
Ricercatori Politecnico in collaborazione con chirurgo urologo progettano un
dispositivo ecogenico
Dispositivo per l’addestramento chirurgico della litotrissia
percutanea (PCNL)
• Brevetto Polimi esteso in US
• Necessità di validare
il prototipo
• Necessità di sviluppare
prototipo con patologie renali
• Scouting aziende Licensing
Dispositivo per l’addestramento chirurgico della litotrissia
percutanea (PCNL)
Licenza esclusiva ad azienda americana
Dispositivo per l’addestramento chirurgico della litotrissia
percutanea (PCNL)
PCNL-Boz
Heart on chip
Heart on Chip
•Microfluidic device able to
generate and culture 3D cell
constructs at the microscale
•Cardiac functional constructs (beating synchronously)
•Actuation mechanism that enables
the cyclic mechanical
stimulation of the cultured constructs
• In vitro drug screening and/or
discovery (i.e. generation of
functional cardiac micro-constructs exploitable as in vitro models
representative of native tissues).
Brevetto Polimi 2015 --> estensione internazionale (PCT) 2016
Heart on Chip
•Microfluidic device able to
generate and culture 3D cell
constructs at the microscale
•Cardiac functional constructs (beating synchronously)
•Actuation mechanism that enables
the cyclic mechanical
stimulation of the cultured constructs
• In vitro drug screening and/or
discovery (i.e. generation of
functional cardiac micro-constructs exploitable as in vitro models
representative of native tissues).
Brevetto Polimi 2015 --> estensione internazionale (PCT) 2016
Heart on Chip
•Microfluidic device able to
generate and culture 3D cell
constructs at the microscale
•Cardiac functional constructs (beating synchronously)
•Actuation mechanism that enables
the cyclic mechanical
stimulation of the cultured constructs
• In vitro drug screening and/or
discovery (i.e. generation of
functional cardiac micro-constructs exploitable as in vitro models
representative of native tissues).
Tra i 10 finalisti di
Creazione di una spin-off Politecnico?
Programma di accelerazione
Eye Tracking device
Eye Tracking device
UVEAL MELANOMA
- Melanoma of the uveal tract (iris, ciliary body
and choroid)
- Incidence 6-7 cases per million people per
year (in Europe)
TREATMENT OPTIONS:
- Eye enucleation
- Brachytherapy
- External beam radiotherapy (stereotactic radiosurgery, proton therapy).
Highly invasive treatments
Eye Tracking device
1) SURGICAL OPERATION tantalum clips application on ocular tumor margins
LIMIT:
• invasiveness
• possible misalignment between clips and lesion
2) PATIENT SETUP
comparison between clip positions from eye radiographies
and planned reference coordinates
LIMIT:
• manual procedure based on a trial-and-error approach
• repeated patient exposure to ionizing radiation
3) DOSE DELIVERY
monitoring of the eye images acquired by a video camera
LIMIT:
• qualitative and inaccurate estimation of the eye position and
movements
• delays due to manual radiation interruption
CURRENT TREATMENT PROCEDURES
Eye Tracking device
Development of a non invasive eye tracking system for ocular proton therapy
ADVANTAGES: • real-time monitoring of 3D tumor position
• automatic verification of setup errors
• instantaneous dose delivery interruption in case of involuntary eye movements
• compatibility with CT/MRI image acquisition for treatment planning
Polimi Research and Patent
Eye Tracking device
MARKET of PARTICLE THERAPY
- 48 centers worldwide (+ 30 centers under constructions in 2015)
- 16 centers dedicated only to ocular proton therapy
- start of proton eye treatments in 1984
- over 20000 eye cancer patients treated with protons
CRITICITA’ Mercato di nicchia
Development of a non invasive eye tracking system for ocular proton therapy
ADVANTAGES: • real-time monitoring of 3D tumor position
• automatic verification of setup errors
• instantaneous dose delivery interruption in case of involuntary eye movements
• compatibility with CT/MRI image acquisition for treatment planning
Polimi Research and Patent
Eye Tracking device
Possibili mercati alternativi? Digital marketing, automotive etc.
Restech: Respiratory Technology
Restech Srl is a spin-off from Politecnico, established in 2010 by the
Biomedical Technologies Laboratory (TBM Lab) in the Department of
Bioengineering. For several years, the TBM Lab has been focusing its research
effort on developing new technologies for investigating the pathophysiology
of the respiratory system and respiratory medicine more generally.
Restech’s mission is to develop highly innovative medical devices and
solutions in the respiratory sector, from research to product engineering,
manufacturing and marketing.
Restech aims to become
a company of
international standing in
the development of
innovative biomedical systems.
http://www.restech.it/en/index.html
http://www.restech.it/en/index.html
http://www.restech.it/en/index.html
http://www.restech.it/en/index.html
RESMON PRO Full
A professional device based on Forced Oscillation Technique (FOT), offering a complete, in-
depth functional assessment for patients with respiratory diseases.
Healthcare providers may personalize the measurement protocol to suit the patient and the
diagnostic objective, tailoring the type of stimulus to be applied and the duration of each
individual test. Once the measurements have been taken, the healthcare worker can
immediately see:
• the standard breathing-pattern indices
• any airflow limitation
• the degree and heterogeneity of the pulmonary obstruction
• the bronchial-reversibility and bronchial-challenge evaluation.
The device requires only a low level of compliance from the
patient, who must simply breathe normally into the device.
As this is a stand-alone device, no external computer is needed in
order to perform the test or to save and view the results.
http://www.restech.it/en/index.html
http://www.restech.it/en/index.html
http://www.restech.it/en/index.html
http://www.restech.it/en/index.html
http://www.restech.it/en/index.html
“Innovation is executing new ideas to create value”
Come la Ricerca diventa Innovazione
Tutela IP IMPATTO
Licensing
Trasferimento Tecnologico
Scouting di aziende Spin-off
Ricerca
Finanziamenti
Brevetti
Invenzioni
INNOVAZIONE
Contacts: Technology Transfer Office
Politecnico di Milano - Piazza Leonardo da Vinci 32, 20133 Milano
Website: http://www.polimi.it/ricerca-scientifica/brevetti/
Roberto Tiezzi Phone: +39 02 23999232
email: [email protected]
Paola Bagnoli Phone: +39 02 23999230
email: [email protected]