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Genetics
What is Genetics
Genetics is the scientific study of heredity.
Heredity is what makes each species unique.
Heredity is the passing on of genes from one generation to the next.
Basic Genetics Terminology Gene
Section of DNA on a chromosome that determines I trait
Allele Different forms of a gene Dominant – allele masks other alleles;
represented by capital letter Recessive – allele is only shown
(epressed) when a dominant gene is not presentIndividuals with identical alleles are called homozygous
Genetics Terminology Cont…
Homozygous When both alleles for a trait are identical
Heterozygous When the alleles for a trait are different
Genotype Actual genetic make-up for a trait
Homozygous dominant = DD Homozygous recessive = dd Heterozygous = Dd
Phenotype The expression of the gene; physical characteristic Descriptive such as tall for TT or Tt
Genetics Terminology Cont… F1 Generation
The first generation of offspring from two parents
F2 Generation The offspring from the breeding of two F1
generation offspring Test Cross
an experimental cross of an individual organism of dominant phenotype but unknown genotype to an organism with a homozygous recessive genotype to determine if the dominant parent is homozygous or heterozygous
Probability & Genetics
Probability is the likelihood that an event will happen.
The principle of probability can be used to predict the outcomes of genetic crosses.
Punnett Squares
Diagram used to predict genetic crosses.
How to use Punnett SquaresA. Choose a letter to represent the alleles.B. Write the genotypes of the parents.C. Determine the possible gametes
(reproductive cells) of each parent.D. Enter the possible gamete at the top and side
of the Punnett square.E. Complete the Punnett square by writing the
alleles from the gametes in the appropriate boxes.
F. Determine the phenotypes of the offspring.G. Using the results of step E and F write down
the genotypic and phenotypic ratios.
More Punnett Squares
Note:Always put The dominantAlleles first In the squares
Punnett Squares Monohybrid & Dihybrid Crosses
Gregor Mendel
Austrian Monk Famous for his work with pea plants He is known as the father of
genetics
Mendel
Mendel’s Work
Mendel used true-breeding plants which means if they were left to breed with themselves they would produce offspring identical to themselves.
Mendel studied 7 different traits in pea plants.
A trait is a specific characteristic that varies from one individual to another.
The Principle of Dominance
The principle of dominance states that some alleles are dominant and others are recessive.
Dominant alleles are always expressed.
Recessive alleles are only expressed if both alleles are recessive.
Segregation & Independent Assortment
The separation of alleles during meiosis to form gamates (sex cells).
The Law of Independent Assortment states that genes for different traits can segregate independently during the formation of gamates.
Law of Segregation
Laws of Inheritance
Mendel’s Principles
The inheritance of biological characteristics are determined by genes.
For two or more forms of a gene, dominance and recessive forms may exist.
Most sexually reproductive organisms have two sets of genes that separate during gamete formation.
Alleles segregate independently.
Genetics Practice Monohybrid
In summer squash, white colored fruit is dominant over yellow. If you place pollen from a yellow–fruited plant on the pistil of a hybrid white–fruited ( heterozygous ) plant, what type of seeds would you expect from the seed which come from this cross?
Problems Continued…
In cats the gene for short hair is dominant over the gene for long hair (angora). A short– haired tom is mated with an Angora female. What are the expected genotypic and phenotypic ratios?
Beyond Dominant and Recessive
Incomplete Dominance – One allele is not completely dominant over the other. White flower crosses with a red = pink flower.
Phenotype of a heterozygous individual is a blend
Beyond Dominant and Recessive Codominance – Both alleles contribute to
the phenotype. Red cow X White Cow = Roan Cow.
Two capital letters are usually used in Punnett square
Beyond Dominant and Recessive Multiple Alleles – More than two alleles control
the phenotype. Coat color of rabbits.
Multiple Alleles – Blood Type
• Blood Type is the phenotype
• A and B are codominant
• Both A and B are dominant to O
• I stands for immunoglobulin
Beyond Dominant and Recessive Polygenic traits – Several genes control the trait. Human skin and eye color; dark colors are usually dominant to lighter colors
Evolution of Polygenic Traits