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Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林林林 ) 2015/3/11

Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

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Introduction  CT and CTA Image 2015/3/11 3 CTA Image(Contrast Image) CT Image(Mask Image)

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Page 1: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

Introduction to the Method of Bone-Subtraction and Our Proposal

Advisor : Ku-Yaw ChangStudent : Wei-Lu Lin(林威如 )

2015/3/11

Page 2: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

2 Outline

Introduction Bone-Subtraction Algorithm Conclusion

2015/3/11

Page 3: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

3 Introduction

CT and CTA Image

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CTA Image(Contrast Image) CT Image(Mask Image)

Page 4: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

4 Introduction

General Segmentation

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Page 5: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

5 Introduction

General Segmentation

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How to Solve ?

Page 6: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

6 Bone-Subtraction

Contrast and Mask Image(Data) Based on Matched Mask Bone Elimination(MMBE) Registration Operation Post-processing

2015/3/11Contrast Image(CTA)

Mask Image(CT)

Page 7: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

7 Bone-Subtraction

2015/3/11

Example

Volume Rendering[1] Surface Rendering

Page 8: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

8 Bone-Subtraction

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Example

Cervical Arteries [2] Legs Arteries [2]

Page 9: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

9 Bone-Subtraction

A Fast Subtraction Algorithm of Brain CT Angiography Image Based on MMBE

Removal of Bone in CT Angiography of the Cervical Arteries by Piecewise MMBE

2015/3/11

Page 10: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

10 A Fast Subtraction Algorithm of Brain CT Angiography Image Based on MMBE

Steps Pre-processing 3D Rigid Registration Based on Mutual Information Bone Mask Extraction

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Page 11: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

11

Step1: Pre-processing Remove Non-interesting Region Mapping

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CTA Image CT Image

A Fast Subtraction Algorithm of Brain CT Angiography Image Based on MMBE

Page 12: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

12

Step2 : 3D Rigid Registration 3D Rigid Registration

Translation Rotation

Mutual Information Similarity Measure

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A Fast Subtraction Algorithm of Brain CT Angiography Image Based on MMBE

Page 13: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

13

Step3 : Bone Mask Extraction Thresholding Refine Bone Mask

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A Fast Subtraction Algorithm of Brain CT Angiography Image Based on MMBE

Page 14: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

14

Result

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A Fast Subtraction Algorithm of Brain CT Angiography Image Based on MMBE

Page 15: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

15 Bone-Subtraction

A Fast Subtraction Algorithm of Brain CT Angiography Image Based on MMBE

Removal of Bone in CT Angiography of the Cervical Arteries by Piecewise MMBE

2015/3/11

Page 16: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

16 Removal of Bone in CT Angiography of the Cervical Arteries by Piecewise MMBE

Steps: Watershed Algorithm on CT Image Register Individually

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Page 17: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

17

Step1: Watershed Algorithm on CT Image

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CT Image CTA Image

Removal of Bone in CT Angiography of the Cervical Arteries by Piecewise MMBE

Page 18: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

18

Step2: Register Individually

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Removal of Bone in CT Angiography of the Cervical Arteries by Piecewise MMBE

Page 19: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

19

Result

2015/3/11

Removal of Bone in CT Angiography of the Cervical Arteries by Piecewise MMBE

Page 20: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

20 Algorithm

Start

Bone Subtraction

Labeling

Thresholding

End

2015/3/11

Page 21: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

21 Algorithm

Start

Bone Subtraction

Labeling

Thresholding

End

2015/3/11

Page 22: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

22 Algorithm

Volume Image Contrast Mask

Binary Image B1 B2

Contrast Image Mask Image

B1 B2

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Page 23: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

23 Algorithm

Thresholding Original Value:130

Thresholding

Bone Subtractio

nLabeling

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Page 24: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

24 Algorithm

Start

Bone Subtraction

Labeling

Thresholding

End

2015/3/11

Page 25: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

25 Algorithm

Registration Region B1 and B2 as Fixed and Moving

Thresholding

Bone Subtractio

nLabeling

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Fixed Image(B1) Moving Image(B2)

After Registrtion -Moving Image(B2)

Transform Parameter

Page 26: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

26 Algorithm

Bone Filter Use B2 Position to Search Around In Contrast Image Filter Limit

Radius = 10 Use Original Value > 350 to Remove in B1

Thresholding

Bone Subtractio

nLabeling

B1 After Registrtion -Moving Image(B2)

Contrast Image Mask Image12

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Page 27: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

27 Algorithm

Bone Filter Use B2 Position to Search Around In Contrast Image Filter Limit

Radius = 10 Use Original Value > 350 to Remove in B1

Thresholding

Bone Subtractio

nLabeling

After Registrtion -Moving Image(B2)Fixed Image(B1)

Contrast Image Mask Image12

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Page 28: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

28 Algorithm

Erosion For B1 Remove Boundary Not to Do Dilation

Reserve Vessel Structure

Thresholding

Bone Subtractio

nLabeling

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Fixed Image(B1)

Contrast Image Mask Image12

After Registrtion -Moving Image(B2)

3

Page 29: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

29 Algorithm

Start

Bone Subtraction

Labeling

Thresholding

End

2015/3/11

Page 30: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

30 Algorithm

Labeling Recovery the Vessel Reference

Contrast Image and B2

Thresholding

Bone Subtractio

nLabeling

B2B1

Mask ImageContrast Image

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Page 31: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

31 Algorithm

Labeling Recovery the Vessel Reference

Contrast Image and B2

Thresholding

Bone Subtractio

nLabeling

B2B1

Contrast Image Mask Image

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Page 32: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

32 Conclusion

Condition Registration

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Contrast Image Mask Image

Page 33: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

33 Conclusion

Condition Registration

2015/3/11

Rotation

Page 34: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

34 Conclusion

Condition Labeling

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Page 35: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

35 Conclusion

Difference Matched Mask Bone Elimination(MMBE) Flexibility

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Page 36: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

36 Reference

[1] DSCT.comhttp://www.dsct.com/index.php/article-series-dual-energy-ct-scientific-evidence-and-clinical-application-27-head-and-neck/

[2] TOSHIBA MEDICAL SYSTEM EUROPEhttp://www.toshiba-medical.eu/eu/product-solutions/computed-tomography/aquilion-one-vision-edition-overview/aquilion-one-vision-edition-advanced-applications/

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Page 37: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

37 Reference

[3] Fangfang Han, Jinzhu Yang, Dazhe Zhao and Hong Zhao, “A Fast Subtraction Algorithm of Brain CT

Angiography Image Based on MMBE,” International Conference on Information and

Automation (ICIA), 2012, pp. 226-229 [4] M. van Straten, H.W. Venema, G.J. Streekstra, C.B.L.M. Majoie, G.J.

den Heeten and C.A. Grimbergen, “Removal of bone in CT angiography of the cervical arteries by piecewise matched mask bone elimination,” Proceeding of the IEEE International Conference on Information and Automation Shenyang, China, June 2012

2015/3/11

Page 38: Introduction to the Method of Bone-Subtraction and Our Proposal Advisor : Ku-Yaw Chang Student : Wei-Lu Lin( 林威如 ) 2015/3/11

38

The EndThank you for listening

2015/3/11