Leukocytosis陳京瑜

Leukocytosis Normal value: 4,500 to 11,000

Infectious diseases Inflammatory disease (such as RA or

allergy) Leukemia Severe emotional or physical stress Tissue damage (such as burns) The use of corticosteroids, underactive

adrenal glands, thyroid gland problems, certain medicines, or removal of the spleen

Atypical lymphocytosis Viral illnesses

EBV, CMV, toxoplasma, syphilis, GBS, hepatitis C Drug reactions –Hypersensitivity

Syndrome Immunisations Radiation Hormonal causes

Addison's disease Auto-immune disorders

RA

Hypersensitivity syndrome A multiorgan drug-induced reaction

Aromatic anticonvulsants phenytoin, carbamazepine, and barbiturates

lamotrigine, minocycline, dapsone, allopurinol, and sulfonamides, abacavir and zalcitabine in HIV-infected patients.

Widespread erythematous eruption that may become purpuric or lichenoid

Fever, facial and periorbital edema, lymphadenopathy, leukocytosis (with atypical lymphocytes and eosinophils), hepatitis, nephritis or pneumonitis.

Reactivation of herpes viruses, especially of herpes virus 6, has been reported to be frequent in this syndrome.

Eosinophilia Normal value: 0~5%

Allergy and drug hypersensitivity: Asthma, hayfever

Parasitic infections Dermatologic disorders

Dermatitis herpetiformis, pemphigus, and erythema multiforme cause eosinophilia.

Hypereosinophilic syndrome persistent eosinophilia of longer than 6 months

associated with organ damage the heart, CNS, skin, and respiratory tract are

commonly involved

Referance eMedicine

http://emedicine.medscape.com/article/956278-overview

http://library.med.utah.edu/WebPath/HEMEHTML/HEME013.html

Harrison’s principal of internal medicine, 17th edition