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Timiºoara, 2006 172 NOILE GHIDURI DE MANAGEMENT AL PNEUMONIILOR NOSOCOMIALE Dorel Sãndesc DEFINIREA TERMENILOR Ghidurile ATS/IDSA definesc trei forme de pneumonie nosocomialã (PN), ceea ce repre- zintã o noutate faþã de ghidurile anterioare: Pneumonia dobânditã în spital (HAP = hospital aquired pneumonia) este pneumonia cu debut la peste 48 h de la internare pe secþie, la pacienþi care nu au fost intubaþi în momentul internãrii (5,7). Pneumonia asociatã ventilaþiei mecanice (VAP = ventilator-associated pneumonia) se referã la pneumonia cu debut la peste 48-72 ore de la intubaþia endotrahealã (6,7). Deºi nu sunt incluºi în aceastã definiþie, pacienþii care necesitã intubaþie dupã ce au dezvoltat o pneumonie severã dobânditã în spital, vor fi monitorizaþi asemeni pacienþilor cu VAP. Pneumonia asociata îngrijirilor medicale specializate (HCAP=healthcare- associated pneumonia) include (7,8,9): - orice pacient spitalizat în acut pentru peste 2 zile în ultimele 90 de zile; - pacienþii din centrele de îngrijire sau cei cu spitalizãri prelungite; - pacienþii cu terapie antibioticã i.v. recentã chemoterapie, îngrijiri ale plãgilor cu maxim 30 de zile înainte de debutul pneumoniei; - pacienþii hemodializaþi; În funcþie de acurateþea datelor existente, a evidenþelor înregistrate, a fost folosit un sistem de evaluare a recomandãrilor: - Nivel I (crescut): evidenþe provenind din trialuri bine conduse, randomizate; INTRODUCERE La a doua ediþie a Cursului Naþional de Ghiduri ºi Protocoale în ATI din 2004 am pre- zentat ghidurile de management al pneumoniilor nosocomiale ºi comunitare severe, bazate pe documentele elaborate de societãþi ºtiinþifice internaþionale de prestigiu (1). Ghidurile de referinþã existente în acel moment în literatura de specialitate erau cele ale American Thoracic Society (ATS) din 1996 (2) ºi Conferinþa de consens între ATS, European Respiratory Society, European Society of Intensive Care Medicine ºi Societe de Reanimation de Langue Francaise din 2002 (3). Iatã cã, într-un interval de timp scurt, importante modificãri apãrute în domeniul pneumoniilor nosocomiale, în ceea ce priveºte atât încadrarea nosologicã, cât ºi profilul etiologic, rezistenþa la antibiotice, strategia diag- nosticã ºi terapeuticã au determinat publicarea, în 2005, a unor noi ghiduri de management de cãtre ATS, de data aceasta în colaborare cu Infectious Disease Society of America (IDSA) (4). Adaptarea continuã a ghidurilor constituie una din calitãþile esenþiale ale acestora, în vederea realizãrii conceptului de living guidelines (ghiduri vii), cunoscându-se faptul cã prin com- plexitatea procesului de editare ºi dinamica specificã, ghidurile riscã sã devinã la scurt timp de la publicare depãºite de noile descoperiri în domeniu. Vom prezenta în continuare o sinteza a ghidurilor ATS/IDSA, la care vom adãuga informaþii din alte resurse bibliografice. U.M.F. Victor Babeº Timiºoara

Noile Ghiduri de Management Al Pneumoniilor Nosocomiale

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    Factori de risc pentru cu germeni multi-rezisten i n HAP, HCAP VAP

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    pacientul Prezen a factorilor de risc pentru HCAP:

    - spitaliz = n antecedente (pn la 90 de zile) - d - pacien i cu spitaliz ri prelungite frecvente - pacien i din centre de ngrijire - terapii n ambulator (incluznd antibiotice) - membri de familie cu germeni multi-rezisten i

    Patologii sau terapii imunosupresoare

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