CORRECTIONS Jiaxiang Zhou, Silvia Villarroya, Wenxin Wang, Mark F. Wyatt, Christopher J. Duxbury, Kristofer J. Thurecht, and Steven M. Howdle*: One-Step Chemoenzymatic Synthesis of Poly(-caprolactone-block-methyl methacrylate) in Su- percritical CO 2 . Volume 39, Number 16, August 8, 2006, pp 5352-5358. In this paper we reported on the kinetics of the simultaneous polymerization of -caprolactone and methyl methacrylate by enzymatic ring-opening polymerization and atom transfer radical polymerization, respectively. We proved the existence of copolymer by numerous techniques, including GPC and NMR spectroscopy. However, in this report we stated that MALDI- TOF analysis of low molecular weight materials clearly showed the presence of block copolymer and NOT a mixture of homopolymers. However, detailed analyses of the MALDI-TOF data reveal the presence of PCL homopolymer; both cyclic and linear. Furthermore, while some peak masses and isotopic patterns may have been indicative of low molecular weight (ca. 1700 Da) PMMA-block-PCL copolymer, continuation of these series beyond these massessas is typical for copolymer series in MALDI spectraswas not observed. Hence, in contrast to the GPC and hydrolysis experiments presented in the report, the MALDI-TOF data do not irrefutably prove the presence of block copolymer. We intend to discuss the effectiveness of MALDI- TOF as an analytical technique for the characterization of these types of block copolymers in a future publication. MA070151N 10.1021/ma070151n Published on Web 02/21/2007 2276 Macromolecules 2007, 40, 2276

One-Step Chemoenzymatic Synthesis of Poly(ε-caprolactone- block -methyl methacrylate) in Supercritical CO 2 . Volume 39, Number 16, August 8, 2006, pp 5352−5358

Download PDF Report

Upload
steven-m
View
215
Download
3

Embed Size (px)

Citation preview

Page 1: One-Step Chemoenzymatic Synthesis of Poly(ε-caprolactone- block -methyl methacrylate) in Supercritical CO 2 . Volume 39, Number 16, August 8, 2006, pp 5352−5358

CORRECTIONS

Jiaxiang Zhou, Silvia Villarroya, Wenxin Wang, Mark F.Wyatt, Christopher J. Duxbury, Kristofer J. Thurecht, andSteven M. Howdle*: One-Step Chemoenzymatic Synthesisof Poly(ε-caprolactone-block-methyl methacrylate) in Su-percritical CO2. Volume 39, Number 16, August 8, 2006, pp5352-5358.

In this paper we reported on the kinetics of the simultaneouspolymerization ofε-caprolactone and methyl methacrylate byenzymatic ring-opening polymerization and atom transfer radicalpolymerization, respectively. We proved the existence ofcopolymer by numerous techniques, including GPC and NMRspectroscopy. However, in this report we stated that MALDI-TOF analysis of low molecular weight materials clearly showedthe presence of block copolymer and NOT a mixture ofhomopolymers. However, detailed analyses of the MALDI-TOFdata reveal the presence of PCL homopolymer; both cyclic andlinear. Furthermore, while some peak masses and isotopicpatterns may have been indicative of low molecular weight (ca.1700 Da) PMMA-block-PCL copolymer, continuation of theseseries beyond these massessas is typical for copolymer seriesin MALDI spectraswas not observed. Hence, in contrast to theGPC and hydrolysis experiments presented in the report, theMALDI-TOF data do not irrefutably prove the presence of blockcopolymer. We intend to discuss the effectiveness of MALDI-TOF as an analytical technique for the characterization of thesetypes of block copolymers in a future publication.

MA070151N

10.1021/ma070151nPublished on Web 02/21/2007

2276 Macromolecules2007,40, 2276