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PROTON BEAM DOSIMETRY Lenka Goceliaková International Summer Student Practice at the Joint Institute for Nuclear Research 6 27 July 2014, Dubna

Proton Beam Dosimetry - Учебно-научный центрnewuc.jinr.ru/img_sections/file/Practice2014/EU/Student... · PROTON BEAM DOSIMETRY Project participant: Lenka Goceliaková

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Page 1: Proton Beam Dosimetry - Учебно-научный центрnewuc.jinr.ru/img_sections/file/Practice2014/EU/Student... · PROTON BEAM DOSIMETRY Project participant: Lenka Goceliaková

PROTON BEAM

DOSIMETRY

Lenka Goceliaková

International Summer Student Practice at the Joint Institute for Nuclear Research

6 – 27 July 2014, Dubna

Page 2: Proton Beam Dosimetry - Учебно-научный центрnewuc.jinr.ru/img_sections/file/Practice2014/EU/Student... · PROTON BEAM DOSIMETRY Project participant: Lenka Goceliaková

PROTON BEAM DOSIMETRY

Project participant:

Lenka Goceliaková

University of Pavol Jozef Šafárik, Faculty of Science,

Košice, Slovakia

Supervisor:

Dr. S.V. Shvidky

Medico – Technical Complex,

Dzhelepov Laboratory of Nuclear Problems,

JINR, Dubna

Page 3: Proton Beam Dosimetry - Учебно-научный центрnewuc.jinr.ru/img_sections/file/Practice2014/EU/Student... · PROTON BEAM DOSIMETRY Project participant: Lenka Goceliaková

AIM OF THE PROJECT

• To verify the correspondence of the dose

distribution in case of therapeutical proton

beam, using film dosimetry and simulations in

the 3D Treatment Planning System (TPS)

• To compare the dose distribution obtained

using EBT films and the 3D TPS

• To compare EBT2 & new EBT3 films

Page 4: Proton Beam Dosimetry - Учебно-научный центрnewuc.jinr.ru/img_sections/file/Practice2014/EU/Student... · PROTON BEAM DOSIMETRY Project participant: Lenka Goceliaková

Why do we need the dosimetry?

• To verify the accuracy of a planning system

calculation algorithm and to determine the

distal dose for the volume.

Page 5: Proton Beam Dosimetry - Учебно-научный центрnewuc.jinr.ru/img_sections/file/Practice2014/EU/Student... · PROTON BEAM DOSIMETRY Project participant: Lenka Goceliaková

Proton beam dosimetry

• Measurements of the radiation dose

0,0001 Gy – 3 Gy

Properties of the Gafchromic films:

•EBT2, EBT3

•self developing dosimetry films

When the active component is exposed to ionizing

radiation, it reacts and forms a green colored

polymer.

Page 6: Proton Beam Dosimetry - Учебно-научный центрnewuc.jinr.ru/img_sections/file/Practice2014/EU/Student... · PROTON BEAM DOSIMETRY Project participant: Lenka Goceliaková

Materials and Methods

• Irradiation EBT2 & EBT3 calibrate films(picture with the small pieces)

• Irradiation EBT2 & EBT3 films

• Scanning of films

• Drawing of calibration curves

• Calculation of the matrices for all films

• Comparison of the dose distribution using EBT films dosimetry and the 3D TPS

• Gamma – index calculation

Page 7: Proton Beam Dosimetry - Учебно-научный центрnewuc.jinr.ru/img_sections/file/Practice2014/EU/Student... · PROTON BEAM DOSIMETRY Project participant: Lenka Goceliaková

Irradiation Method • The films were irradiated individually with protons in a

water tank;

• The proton beams pass through colimator, water tank and stops in radiochromic film;

• Films were places in the water phantom and positioned with a angle 5 degrees slope to the beam axis in the horizontal plane

Page 8: Proton Beam Dosimetry - Учебно-научный центрnewuc.jinr.ru/img_sections/file/Practice2014/EU/Student... · PROTON BEAM DOSIMETRY Project participant: Lenka Goceliaková

Films Scanning

• Reflection Method:

• light from the transmitter bounces off a reflector placed

outside of the housing and travels back to the receiver.

Positive Method:

• a beam of light shines directly from the transmitter to the

receiver.

• An object is detected when it passes between transmitter

and receiver and blocks the beam of light.

Page 9: Proton Beam Dosimetry - Учебно-научный центрnewuc.jinr.ru/img_sections/file/Practice2014/EU/Student... · PROTON BEAM DOSIMETRY Project participant: Lenka Goceliaková

Calibration curve

VcbaDose

pixelsV

0,98165c

-34,25479b

-0,84095

a

EBT3 – Positive Method

110 120 130 140 150 160 170 180 190 200 210

0,0

0,5

1,0

1,5

2,0

2,5

3,0

Do

se

(G

y)

Value of pixel

Page 10: Proton Beam Dosimetry - Учебно-научный центрnewuc.jinr.ru/img_sections/file/Practice2014/EU/Student... · PROTON BEAM DOSIMETRY Project participant: Lenka Goceliaková

Calibration curve

10 20 30 40 50 60 70 80 90 100 110 120 130 140

0,0

0,5

1,0

1,5

2,0

2,5

3,0

Do

se

(G

y)

Value of Pixel

VcbaDose

EBT3 – Reflective Method

pixels V

0,95327c

-10,01656b

0,12236

a

Page 11: Proton Beam Dosimetry - Учебно-научный центрnewuc.jinr.ru/img_sections/file/Practice2014/EU/Student... · PROTON BEAM DOSIMETRY Project participant: Lenka Goceliaková

Comparison between films and planning

system

9060

60

60

10

203040

50

60

70

80

90

20 40 60 80 100 120 140 160

10

20

30

40

50

60

70

80

90

Wid

th(m

m)

Depth(mm)

Comparison between EBT2 (black) and Planning System (red) for Positive Method

dL=3mm; dD=3%

G <= 1 (10%): 80.8%

G <= 1 (20%): 72%

G <= 1 (30%): 59%

G <= 1 (40%): 11.5%

G <= 1 (50%): 71%

G <= 1 (60%): 98.6%

G <= 1 (70%): 100%

G <= 1 (80%): 99.4%

G <= 1 (90%): 99.7%

G <= 1 (100%): 100%

G <= 1 (>90%): 99.7%

Page 12: Proton Beam Dosimetry - Учебно-научный центрnewuc.jinr.ru/img_sections/file/Practice2014/EU/Student... · PROTON BEAM DOSIMETRY Project participant: Lenka Goceliaková

10

20

30

4050

60

60

60

60

60

70

80

90

60

60

6060

60

6060

60

60

70

70

70

70

60

60

60

60

60

60

60

60

10

20

30

40

50

60

70

80

90

20 40 60 80 100 120 140

10

20

30

40

50

60

70

80W

idth

(mm

)

Depth(mm)

Comparison between EBT3 (black) and Planning System (red) for Positive Method

dL=3mm; dD=3%

G <= 1 (10%): 90.4%

G <= 1 (20%): 73.6%

G <= 1 (30%): 58.8%

G <= 1 (40%): 10.6%

G <= 1 (50%): 59.5%

G <= 1 (60%): 91.9%

G <= 1 (70%): 99.6%

G <= 1 (80%): 100%

G <= 1 (90%): 100%

G <= 1 (100%): 100%

G <= 1 (>90%): 100%

Page 13: Proton Beam Dosimetry - Учебно-научный центрnewuc.jinr.ru/img_sections/file/Practice2014/EU/Student... · PROTON BEAM DOSIMETRY Project participant: Lenka Goceliaková

20 30

40

4050

60

60

80

90

90

50

50

50

70

40

40

50

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60

10

203040

50

60

70

80

90

20 40 60 80 100 120 140

10

20

30

40

50

60

70

80W

idth

(m

m)

Depth(mm)

Comparison between EBT2 (black) and Planning System (red) for Reflective Method

dL=3mm; dD=3%

G <= 1 (10%): 59.3%

G <= 1 (20%): 80.3%

G <= 1 (30%): 93.9%

G <= 1 (40%): 58.4%

G <= 1 (50%): 77.4%

G <= 1 (60%): 99.6%

G <= 1 (70%): 97.8%

G <= 1 (80%): 90%

G <= 1 (90%): 80.6%

G <= 1 (100%): 100%

G <= 1 (>90%): 80.7%

Page 14: Proton Beam Dosimetry - Учебно-научный центрnewuc.jinr.ru/img_sections/file/Practice2014/EU/Student... · PROTON BEAM DOSIMETRY Project participant: Lenka Goceliaková

40

5050

50

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60

6080

5050

50

50

50

70

60

10

20

30

40

50

60

70

80

90

20 40 60 80 100 120 140

20

40

60

80

Wid

th(m

m)

Depth(mm)

Comparison between EBT3 (black) and Planning System (red) for Reflective Method

dL=3mm; dD=3%

G <= 1 (10%): 67.5%

G <= 1 (20%): 72.2%

G <= 1 (30%): 87.1%

G <= 1 (40%): 95.8%

G <= 1 (50%): 99.5%

G <= 1 (60%): 93.5%

G <= 1 (70%): 96.1%

G <= 1 (80%): 75.9%

G <= 1 (90%): 71%

G <= 1 (100%): 100%

G <= 1 (>90%): 71.2%

Page 15: Proton Beam Dosimetry - Учебно-научный центрnewuc.jinr.ru/img_sections/file/Practice2014/EU/Student... · PROTON BEAM DOSIMETRY Project participant: Lenka Goceliaková

RESULTS

• Positive Method: G – index more 90%

• Reflective Method: G – index less 90%

• Preferable is positive method of scanning

Page 16: Proton Beam Dosimetry - Учебно-научный центрnewuc.jinr.ru/img_sections/file/Practice2014/EU/Student... · PROTON BEAM DOSIMETRY Project participant: Lenka Goceliaková

Conclusions

• Radiochromic films are accurate detectors for

proton beam dosimetry

• Measured date are consistent with the date

from PS in the acceptable deviation (3%)

• Results from G – index comply requierement

for the planning of proton therapy

Page 17: Proton Beam Dosimetry - Учебно-научный центрnewuc.jinr.ru/img_sections/file/Practice2014/EU/Student... · PROTON BEAM DOSIMETRY Project participant: Lenka Goceliaková

THANK YOU FOR YOUR

ATTENTION !

Special thanks to: My project consultant:

Konstantin Shipulin – Medico-Technical Complex,

Dzhelepov Laboratory of Nuclear Problems,

JINR, Dubna