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PROTON BEAM
DOSIMETRY
Lenka Goceliaková
International Summer Student Practice at the Joint Institute for Nuclear Research
6 – 27 July 2014, Dubna
PROTON BEAM DOSIMETRY
Project participant:
Lenka Goceliaková
University of Pavol Jozef Šafárik, Faculty of Science,
Košice, Slovakia
Supervisor:
Dr. S.V. Shvidky
Medico – Technical Complex,
Dzhelepov Laboratory of Nuclear Problems,
JINR, Dubna
AIM OF THE PROJECT
• To verify the correspondence of the dose
distribution in case of therapeutical proton
beam, using film dosimetry and simulations in
the 3D Treatment Planning System (TPS)
• To compare the dose distribution obtained
using EBT films and the 3D TPS
• To compare EBT2 & new EBT3 films
Why do we need the dosimetry?
• To verify the accuracy of a planning system
calculation algorithm and to determine the
distal dose for the volume.
Proton beam dosimetry
• Measurements of the radiation dose
0,0001 Gy – 3 Gy
Properties of the Gafchromic films:
•EBT2, EBT3
•self developing dosimetry films
When the active component is exposed to ionizing
radiation, it reacts and forms a green colored
polymer.
Materials and Methods
• Irradiation EBT2 & EBT3 calibrate films(picture with the small pieces)
• Irradiation EBT2 & EBT3 films
• Scanning of films
• Drawing of calibration curves
• Calculation of the matrices for all films
• Comparison of the dose distribution using EBT films dosimetry and the 3D TPS
• Gamma – index calculation
Irradiation Method • The films were irradiated individually with protons in a
water tank;
• The proton beams pass through colimator, water tank and stops in radiochromic film;
• Films were places in the water phantom and positioned with a angle 5 degrees slope to the beam axis in the horizontal plane
Films Scanning
• Reflection Method:
• light from the transmitter bounces off a reflector placed
outside of the housing and travels back to the receiver.
Positive Method:
• a beam of light shines directly from the transmitter to the
receiver.
• An object is detected when it passes between transmitter
and receiver and blocks the beam of light.
Calibration curve
VcbaDose
pixelsV
0,98165c
-34,25479b
-0,84095
a
EBT3 – Positive Method
110 120 130 140 150 160 170 180 190 200 210
0,0
0,5
1,0
1,5
2,0
2,5
3,0
Do
se
(G
y)
Value of pixel
Calibration curve
10 20 30 40 50 60 70 80 90 100 110 120 130 140
0,0
0,5
1,0
1,5
2,0
2,5
3,0
Do
se
(G
y)
Value of Pixel
VcbaDose
EBT3 – Reflective Method
pixels V
0,95327c
-10,01656b
0,12236
a
Comparison between films and planning
system
9060
60
60
10
203040
50
60
70
80
90
20 40 60 80 100 120 140 160
10
20
30
40
50
60
70
80
90
Wid
th(m
m)
Depth(mm)
Comparison between EBT2 (black) and Planning System (red) for Positive Method
dL=3mm; dD=3%
G <= 1 (10%): 80.8%
G <= 1 (20%): 72%
G <= 1 (30%): 59%
G <= 1 (40%): 11.5%
G <= 1 (50%): 71%
G <= 1 (60%): 98.6%
G <= 1 (70%): 100%
G <= 1 (80%): 99.4%
G <= 1 (90%): 99.7%
G <= 1 (100%): 100%
G <= 1 (>90%): 99.7%
10
20
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4050
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90
60
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10
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80
90
20 40 60 80 100 120 140
10
20
30
40
50
60
70
80W
idth
(mm
)
Depth(mm)
Comparison between EBT3 (black) and Planning System (red) for Positive Method
dL=3mm; dD=3%
G <= 1 (10%): 90.4%
G <= 1 (20%): 73.6%
G <= 1 (30%): 58.8%
G <= 1 (40%): 10.6%
G <= 1 (50%): 59.5%
G <= 1 (60%): 91.9%
G <= 1 (70%): 99.6%
G <= 1 (80%): 100%
G <= 1 (90%): 100%
G <= 1 (100%): 100%
G <= 1 (>90%): 100%
20 30
40
4050
60
60
80
90
90
50
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70
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60
10
203040
50
60
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80
90
20 40 60 80 100 120 140
10
20
30
40
50
60
70
80W
idth
(m
m)
Depth(mm)
Comparison between EBT2 (black) and Planning System (red) for Reflective Method
dL=3mm; dD=3%
G <= 1 (10%): 59.3%
G <= 1 (20%): 80.3%
G <= 1 (30%): 93.9%
G <= 1 (40%): 58.4%
G <= 1 (50%): 77.4%
G <= 1 (60%): 99.6%
G <= 1 (70%): 97.8%
G <= 1 (80%): 90%
G <= 1 (90%): 80.6%
G <= 1 (100%): 100%
G <= 1 (>90%): 80.7%
40
5050
50
50
60
6080
5050
50
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60
10
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20 40 60 80 100 120 140
20
40
60
80
Wid
th(m
m)
Depth(mm)
Comparison between EBT3 (black) and Planning System (red) for Reflective Method
dL=3mm; dD=3%
G <= 1 (10%): 67.5%
G <= 1 (20%): 72.2%
G <= 1 (30%): 87.1%
G <= 1 (40%): 95.8%
G <= 1 (50%): 99.5%
G <= 1 (60%): 93.5%
G <= 1 (70%): 96.1%
G <= 1 (80%): 75.9%
G <= 1 (90%): 71%
G <= 1 (100%): 100%
G <= 1 (>90%): 71.2%
RESULTS
• Positive Method: G – index more 90%
• Reflective Method: G – index less 90%
• Preferable is positive method of scanning
Conclusions
• Radiochromic films are accurate detectors for
proton beam dosimetry
• Measured date are consistent with the date
from PS in the acceptable deviation (3%)
• Results from G – index comply requierement
for the planning of proton therapy
THANK YOU FOR YOUR
ATTENTION !
Special thanks to: My project consultant:
Konstantin Shipulin – Medico-Technical Complex,
Dzhelepov Laboratory of Nuclear Problems,
JINR, Dubna