1
l uc (1)ATGGAAGACGCCAAAAACATAAAGAAAGGCCCGGCGCCATTCTATCCTCTAGAGGATGGAACCGCTGGAGAGCAACTGCATAAGGCTATGAAGAGATACG l uc * (1)ATGGAAGACGCCAAGAACATCAAGAAGGGTCCTGCACCGTTCTACCCACTCGAGGACGGTACAGCTGGCGAACAGCTCCACAAGGCGATGAAGCGGTACG l uc (101)CCCTGGTTCCTGGAACAATTGCTTTTACAGATGCACATATCGAGGTGAACATCACGTACGCGGAATACTTCGAAATGTCCGTTCGGTTGGCAGAAGCTAT l uc * (101)CTCTGGTACCCGGCACTATCGCTTTCACCGACGCCCACATTGAGGTCAACATCACGTACGCTGAGTACTTCGAAATGTCCGTCAGGCTGGCCGAAGCCAT l uc (201)GAAACGATATGGGCTGAATACAAATCACAGAATCGTCGTATGCAGTGAAAACTCTCTTCAATTCTTTATGCCGGTGTTGGGCGCGTTATTTATCGGAGTT l uc * (201)GAAGCGCTACGGCCTGAACACGAACCACAGAATCGTCGTATGCTCCGAGAACTCCCTCCAGTTCTTCATGCCTGTACTGGGGGCGCTGTTCATCGGGGTT l uc (301)GCAGTTGCGCCCGCGAACGACATTTATAATGAACGTGAATTGCTCAACAGTATGAACATTTCGCAGCCTACCGTAGTGTTTGTTTCCAAAAAGGGGTTGC l uc * (301)GCAGTCGCTCCGGCGAACGACATATACAATGAGCGGGAACTCCTGAACAGCATGAACATCTCCCAGCCTACCGTCGTATTCGTGTCGAAGAAGGGCCTCC l uc (401)AAAAAATTTTGAACGTGCAAAAAAAATTACCAATAATCCAGAAAATTATTATCATGGATTCTAAAACGGATTACCAGGGATTTCAGTCGATGTACACGTT l uc * (401)AGAAGATCCTCAACGTCCAGAAGAAGCTGCCGATCATCCAGAAGATCATCATCATGGACAGCAAGACCGACTATCAGGGCTTTCAGTCCATGTACACGTT l uc (501)CGTCACATCTCATCTACCTCCCGGTTTTAATGAATACGATTTTGTACCAGAGTCCTTTGATCGTGACAAAACAATTGCACTGATAATGAATTCCTCTGGA l uc * (501)TGTCACCTCGCACTTGCCACCAGGGTTCAACGAGTACGATTTCGTTCCCGAGAGCTTCGATAGGGACAAGACGATAGCTCTGATCATGAACAGCAGCGGC l uc (601)TCTACTGGGTTACCTAAGGGTGTGGCCCTTCCGCATAGAACTGCCTGCGTCAGATTCTCGCATGCCAGAGATCCTATTTTTGGCAATCAAATCATTCCGG l uc * (601)TCGACAGGGCTCCCAAAGGGTGTTGCCCTCCCACATCGTACTGCGTGCGTCCGGTTCTCTCACGCACGTGATCCCATATTCGGCAACCAGATCATCCCGG l uc (701)ATACTGCGATTTTAAGTGTTGTTCCATTCCATCACGGTTTTGGAATGTTTACTACACTCGGATATTTGATATGTGGATTTCGAGTCGTCTTAATGTATAG l uc * (701)ACACCGCAATCCTGAGCGTGGTCCCGTTCCACCACGGCTTTGGGATGTTCACAACACTTGGCTACCTGATCTGCGGGTTTAGGGTTGTACTCATGTACCG l uc (801)ATTTGAAGAAGAGCTGTTTTTACGATCCCTTCAGGATTACAAAATTCAAAGTGCGTTGCTAGTACCAACCCTATTTTCATTCTTCGCCAAAAGCACTCTG l uc * (801)CTTCGAAGAGGAACTGTTCCTTCGGAGCCTCCAGGACTACAAGATCCAGTCTGCGCTCCTTGTCCCAACCTTGTTCTCCTTCTTCGCGAAGTCAACCCTT l uc (901)ATTGACAAATACGATTTATCTAATTTACACGAAATTGCTTCTGGGGGCGCACCTCTTTCGAAAGAAGTCGGGGAAGCGGTTGCAAAACGCTTCCATCTTC l uc * (901)ATCGACAAGTACGATCTGTCTAACCTCCATGAGATCGCCTCGGGCGGAGCACCACTCTCTAAGGAGGTCGGAGAAGCTGTTGCGAAGAGATTCCATCTGC l uc (1001)CAGGGATACGACAAGGATATGGGCTCACTGAGACTACATCAGCTATTCTGATTACACCCGAGGGGGATGATAAACCGGGCGCGGTCGGTAAAGTTGTTCC l uc * (1001)CCGGGATCCGTCAGGGGTATGGCCTTACTGAAACCACTTCGGCGATTCTCATCACTCCCGAAGGTGATGACAAGCCGGGAGCAGTGGGTAAGGTGGTCCC l uc (1101)ATTTTTTGAAGCGAAGGTTGTGGATCTGGATACCGGGAAAACGCTGGGCGTTAATCAGAGAGGCGAATTATGTGTCAGAGGACCTATGATTATGTCCGGT l uc * (1101)CTTCTTCGAAGCTAAGGTCGTCGATCTCGATACCGGTAAGACCCTCGGGGTTAACCAAAGGGGAGAGCTCTGCGTTAGGGGCCCGATGATCATGTCTGGC l uc (1201)TATGTAAACAATCCGGAAGCGACCAACGCCTTGATTGACAAGGATGGATGGCTACATTCTGGAGACATAGCTTACTGGGACGAAGACGAACACTTCTTCA l uc * (1201)TATGTGAACAACCCAGAAGCTACGAATGCGCTCATCGACAAAGACGGATGGCTGCATTCGGGAGACATCGCCTACTGGGATGAAGATGAGCACTTCTTCA l uc (1301)TAGTTGACCGCTTGAAGTCTTTAATTAAATACAAAGGATATCAGGTGGCCCCCGCTGAATTGGAATCGATATTGTTACAACACCCCAACATCTTCGACGC l uc * (1301)TCGTTGACAGACTGAAGAGCTTGATCAAGTACAAGGGGTATCAGGTCGCTCCTGCTGAGCTGGAGTCAATCCTCCTCCAGCACCCGAACATCTTCGACGC l uc (1401)GGGCGTGGCAGGTCTTCCCGACGATGACGCCGGTGAACTTCCCGCCGCCGTTGTTGTTTTGGAGCACGGAAAGACGATGACGGAAAAAGAGATCGTGGAT l uc * (1401)AGGCGTCGCAGGCTTGCCTGATGACGATGCCGGCGAACTTCCTGCCGCTGTTGTTGTCTTGGAGCACGGTAAGACCATGACGGAGAAGGAGATTGTGGAC l uc (1501)TACGTGGCCAGTCAAGTAACAACCGCGAAAAAGTTGCGCGGAGGAGTTGTGTTTGTGGACGAAGTACCGAAAGGTCTTACCGGAAAACTCGACGCAAGAA l uc * (1501)TATGTCGCCTCTCAGGTCACCACGGCGAAGAAGCTGCGTGGCGGTGTCGTCTTCGTTGATGAGGTTCCGAAGGGCCTGACGGGGAAACTCGACGCCCGCA l uc (1601)AAATCAGAGAGATCCTCATAAAGGCCAAGAAGGGCGGAAAGTCCAAATTGTAA l uc * (1601)AGATCCGGGAGATCCTGATCAAGGCGAAGAAGGGTGGAAAGTCGAAGCTTTAG Supplementary Figure 1.

Supplementary Figure 1

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Supplementary Figure 1. - PowerPoint PPT Presentation

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luc (1)ATGGAAGACGCCAAAAACATAAAGAAAGGCCCGGCGCCATTCTATCCTCTAGAGGATGGAACCGCTGGAGAGCAACTGCATAAGGCTATGAAGAGATACG luc* (1)ATGGAAGACGCCAAGAACATCAAGAAGGGTCCTGCACCGTTCTACCCACTCGAGGACGGTACAGCTGGCGAACAGCTCCACAAGGCGATGAAGCGGTACG

luc (101)CCCTGGTTCCTGGAACAATTGCTTTTACAGATGCACATATCGAGGTGAACATCACGTACGCGGAATACTTCGAAATGTCCGTTCGGTTGGCAGAAGCTAT luc* (101)CTCTGGTACCCGGCACTATCGCTTTCACCGACGCCCACATTGAGGTCAACATCACGTACGCTGAGTACTTCGAAATGTCCGTCAGGCTGGCCGAAGCCAT

luc (201)GAAACGATATGGGCTGAATACAAATCACAGAATCGTCGTATGCAGTGAAAACTCTCTTCAATTCTTTATGCCGGTGTTGGGCGCGTTATTTATCGGAGTT luc* (201)GAAGCGCTACGGCCTGAACACGAACCACAGAATCGTCGTATGCTCCGAGAACTCCCTCCAGTTCTTCATGCCTGTACTGGGGGCGCTGTTCATCGGGGTT

luc (301)GCAGTTGCGCCCGCGAACGACATTTATAATGAACGTGAATTGCTCAACAGTATGAACATTTCGCAGCCTACCGTAGTGTTTGTTTCCAAAAAGGGGTTGC luc* (301)GCAGTCGCTCCGGCGAACGACATATACAATGAGCGGGAACTCCTGAACAGCATGAACATCTCCCAGCCTACCGTCGTATTCGTGTCGAAGAAGGGCCTCC

luc (401)AAAAAATTTTGAACGTGCAAAAAAAATTACCAATAATCCAGAAAATTATTATCATGGATTCTAAAACGGATTACCAGGGATTTCAGTCGATGTACACGTT luc* (401)AGAAGATCCTCAACGTCCAGAAGAAGCTGCCGATCATCCAGAAGATCATCATCATGGACAGCAAGACCGACTATCAGGGCTTTCAGTCCATGTACACGTT

luc (501)CGTCACATCTCATCTACCTCCCGGTTTTAATGAATACGATTTTGTACCAGAGTCCTTTGATCGTGACAAAACAATTGCACTGATAATGAATTCCTCTGGA luc* (501)TGTCACCTCGCACTTGCCACCAGGGTTCAACGAGTACGATTTCGTTCCCGAGAGCTTCGATAGGGACAAGACGATAGCTCTGATCATGAACAGCAGCGGC

luc (601)TCTACTGGGTTACCTAAGGGTGTGGCCCTTCCGCATAGAACTGCCTGCGTCAGATTCTCGCATGCCAGAGATCCTATTTTTGGCAATCAAATCATTCCGG luc* (601)TCGACAGGGCTCCCAAAGGGTGTTGCCCTCCCACATCGTACTGCGTGCGTCCGGTTCTCTCACGCACGTGATCCCATATTCGGCAACCAGATCATCCCGG

luc (701)ATACTGCGATTTTAAGTGTTGTTCCATTCCATCACGGTTTTGGAATGTTTACTACACTCGGATATTTGATATGTGGATTTCGAGTCGTCTTAATGTATAG luc* (701)ACACCGCAATCCTGAGCGTGGTCCCGTTCCACCACGGCTTTGGGATGTTCACAACACTTGGCTACCTGATCTGCGGGTTTAGGGTTGTACTCATGTACCG

luc (801)ATTTGAAGAAGAGCTGTTTTTACGATCCCTTCAGGATTACAAAATTCAAAGTGCGTTGCTAGTACCAACCCTATTTTCATTCTTCGCCAAAAGCACTCTG luc* (801)CTTCGAAGAGGAACTGTTCCTTCGGAGCCTCCAGGACTACAAGATCCAGTCTGCGCTCCTTGTCCCAACCTTGTTCTCCTTCTTCGCGAAGTCAACCCTT

luc (901)ATTGACAAATACGATTTATCTAATTTACACGAAATTGCTTCTGGGGGCGCACCTCTTTCGAAAGAAGTCGGGGAAGCGGTTGCAAAACGCTTCCATCTTC luc* (901)ATCGACAAGTACGATCTGTCTAACCTCCATGAGATCGCCTCGGGCGGAGCACCACTCTCTAAGGAGGTCGGAGAAGCTGTTGCGAAGAGATTCCATCTGC

luc (1001)CAGGGATACGACAAGGATATGGGCTCACTGAGACTACATCAGCTATTCTGATTACACCCGAGGGGGATGATAAACCGGGCGCGGTCGGTAAAGTTGTTCC luc* (1001)CCGGGATCCGTCAGGGGTATGGCCTTACTGAAACCACTTCGGCGATTCTCATCACTCCCGAAGGTGATGACAAGCCGGGAGCAGTGGGTAAGGTGGTCCC

luc (1101)ATTTTTTGAAGCGAAGGTTGTGGATCTGGATACCGGGAAAACGCTGGGCGTTAATCAGAGAGGCGAATTATGTGTCAGAGGACCTATGATTATGTCCGGT luc* (1101)CTTCTTCGAAGCTAAGGTCGTCGATCTCGATACCGGTAAGACCCTCGGGGTTAACCAAAGGGGAGAGCTCTGCGTTAGGGGCCCGATGATCATGTCTGGC

luc (1201)TATGTAAACAATCCGGAAGCGACCAACGCCTTGATTGACAAGGATGGATGGCTACATTCTGGAGACATAGCTTACTGGGACGAAGACGAACACTTCTTCA luc* (1201)TATGTGAACAACCCAGAAGCTACGAATGCGCTCATCGACAAAGACGGATGGCTGCATTCGGGAGACATCGCCTACTGGGATGAAGATGAGCACTTCTTCA

luc (1301)TAGTTGACCGCTTGAAGTCTTTAATTAAATACAAAGGATATCAGGTGGCCCCCGCTGAATTGGAATCGATATTGTTACAACACCCCAACATCTTCGACGC luc* (1301)TCGTTGACAGACTGAAGAGCTTGATCAAGTACAAGGGGTATCAGGTCGCTCCTGCTGAGCTGGAGTCAATCCTCCTCCAGCACCCGAACATCTTCGACGC

luc (1401)GGGCGTGGCAGGTCTTCCCGACGATGACGCCGGTGAACTTCCCGCCGCCGTTGTTGTTTTGGAGCACGGAAAGACGATGACGGAAAAAGAGATCGTGGAT luc* (1401)AGGCGTCGCAGGCTTGCCTGATGACGATGCCGGCGAACTTCCTGCCGCTGTTGTTGTCTTGGAGCACGGTAAGACCATGACGGAGAAGGAGATTGTGGAC

luc (1501)TACGTGGCCAGTCAAGTAACAACCGCGAAAAAGTTGCGCGGAGGAGTTGTGTTTGTGGACGAAGTACCGAAAGGTCTTACCGGAAAACTCGACGCAAGAA luc* (1501)TATGTCGCCTCTCAGGTCACCACGGCGAAGAAGCTGCGTGGCGGTGTCGTCTTCGTTGATGAGGTTCCGAAGGGCCTGACGGGGAAACTCGACGCCCGCA

luc (1601)AAATCAGAGAGATCCTCATAAAGGCCAAGAAGGGCGGAAAGTCCAAATTGTAA luc* (1601)AGATCCGGGAGATCCTGATCAAGGCGAAGAAGGGTGGAAAGTCGAAGCTTTAG

Supplementary Figure 1.

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