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“The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy University of Florida

“The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

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Page 1: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

“The Faces of Substance Abuse in America”It’s Ugly and Getting Uglier

by

Paul L. Doering, M.S.

Distinguished Service Professor, Emeritus

College of Pharmacy

University of Florida

Page 2: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

The Two Faces of Drug Abuse

• Faces of those who use and abuse.http://www.facesofmeth.us/main.htm

• Faces of the drugs being used.– News Flash: Quaalude is “out”– Breaking News: “Bath Salts” are “in” out

Page 3: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

HEALTH PROFESSIONALS KNOW A LOT ABOUT DRUGS, BUT………...

• Many curricula do not contain coursework in substance abuse

• Thus, they are not schooled in this “other” use of pharmaceutical products

• Most have limited personal experience with recreational drugs (thankfully)

• But, these persons are often sought out by parents, family members, etc. for help

Page 4: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy
Page 5: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

The Faces of Three Drug Experts From the 1960s

Janis Lyn Joplin Born- 1/19/43Died- 10/4/70

James Marshall HendrixBorn- 11/27/42Died- 9/18/70

Paul Louis DoeringBorn- 2/25/49Not Dead Yet

Page 6: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Makin’ the “Big Time”

Page 7: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Florida IS the Face of Drug Abuse in Our Country

http://abcnews.go.com/WNT/video/florida-drug-bust-targets-doctors-presibtion-illegal-painkillers-pill-mill-dea-12985087

Page 8: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

And It’s a Local Problem too….

Page 9: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

But it is a knotty problem…..

Page 10: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy
Page 11: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy
Page 12: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Marijuana: The flowering top of the pistillate plant (or female) of the genus and species, Cannabis Sativa, Family Moraceae.Lecture by Prof. Carl Johnson in Weeds and Seeds course, circa 1969

Page 13: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

“Square Grouper” that used to fall into Biscayne Bay in Miami

Page 14: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Lot’s of Pot!

Page 15: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

The New Face of Marijuana (aka Spice or K2)

Page 16: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

“Synthetic Marijuana”

Cannabicyclohexanol

JWH-018

HU-210JWH-073

Tetrahydrocannabinol

Page 17: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

For More Information:http://info.publicintelligence.net/spicealert.pdf

Page 18: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

DEA Re-Scheduling

On November 24, 2010, the DEA notified the public through the Federal Register of their intent to temporarily control five

synthetic cannabinoid chemicals found in so-called “fake pot”

products such as K2 and Spice.

Page 19: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

The Face of Real Bath Salts

•magnesium sulfate (Epsom salts)

•sodium chloride (table salt)

•sodium bicarbonate (baking soda)

•sodium hexametaphosphate (Calgon, amorphous/glassy sodium metaphosphate)

•sodium sesquicarbonate

•borax

Page 20: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

The Face of “Not Real” Bath Salts

Methylenedioxypyrovalerone (MDPV)

Some Brand Names:

Cloud 9, Ivory Wave, Ocean, Charge Plus, White Lightning, Scarface, Hurricane Charlie, Red Dove and White Dove.

Page 21: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Emergency Re-Scheduling in Florida

Page 22: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Digital Drugs

Page 23: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Digital Drugs

Page 24: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Example of a Digital Drug

Page 25: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

In Your Face: Nitrous Oxide

• Synonyms:– nitrous, laughing gas, whippets, “Blue Nun”

• Mental effects:– giddiness, silly laughter, buzzing or ringing in ears

• Duration of effect is only 2-3 minutes• Danger:

– hypoxia, possible nerve damage with prolonged use

Page 26: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy
Page 27: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Whip-Its

Page 28: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Individual Cylinders of N20

Page 29: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Whipped Cream Dispenser

                                                                                             

Page 30: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

The Many Recognizable Faces of Ecstasy

Page 31: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

The Fashionable Face of Ecstasy

Page 32: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

The Kinda Weird Faces of People Rolling

Page 33: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

The Three Faces of Coke

Page 34: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

An Impromptu Drug Delivery Device

This is called a “stem” on the street

Page 35: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

From The Face of a Meth User

Page 36: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Meth Bugs

Page 37: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

The Face of a Burn Victim from Meth lab- 19 yo

Page 38: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Oxycontin Express

http://www.huffingtonpost.com/currenttvs-vanguard/vanguard-season-premiere_b_320867.html

Page 39: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Pharmaceutical Drugs are “In”

• Obtained from legal prescriptions

• Given or sold among friends

• Stolen from medicine cabinets

• Stolen from pharmacies

Page 40: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

The Ugly Face of Prescription Drug Abuse In America

http://www.cdc.gov/nchs/data/hus/hus10_InBrief.pdf

Page 41: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

The Figures Fit the Face

• >27,000 deaths from Rx drug Ods in 2007– five-fold increase since 1990

• declining mortality rates for all other conditions– including heart disease and cancer

• OD deaths from Rx opioids are exceeding deaths from heroin and cocaine overdoses combined.

Page 42: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

The Figures Fit the Face (cont’d)

• Drug-induced deaths (which includes all drugs) is approaching the number of deaths from motor vehicle crashes.

• Drug abuse deaths have also surpassed deaths from suicide, homicide, and fire arms.

Page 43: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Pharmaceutical vs Street Drugs

• Safer– identity– purity– less HIV / hepatitis risk

• Safer because "it's just a prescription drug"• Low or no acquisition cost

– Medicaid, Workers’ Comp, private insurance, VA, Indian Health Service

Page 44: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Ritalin LA 20 mg Ritalin LA 30 mg Ritalin LA 40 mg

Ritalin 10 mg Ritalin 5 mg

Concerta ER 18 mg

Ritalin SR 20 mg

Concerta ER 54 mgConcerta ER 36 mg

The Different Faces of “Ritalin”

Page 45: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Stimulant

Identification

Page 46: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

OxyContin (oxycodone HCl)

Page 47: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

The Face of Grandaddy Morphine

Page 48: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

The Face of Codeine (aka methoxymorphine

Page 49: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

The Face of Hydrocodone

Page 50: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

The All-Too Familiar Face of Oxycodone

Page 51: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

The Face of Methadone

Page 52: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

The Face of Meperidine

Page 53: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Comparing the Faces

MorphineCodeine Hydrocodone

OxycodoneMethadoneMeperidine

Page 54: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Rohypnol is now wearing a mask to hide his sneaky face

Page 55: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Xanax- A Household Word

Page 56: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Depressants: Benzodiazepines and non-benzodiazepines

Valium 2 mg Valium 5 mg Valium 10 mg

Xanax 0.5 mg

Xanax 1 mg Xanax 2 mg

Page 57: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Depressants Identification

Page 58: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Depressants Identification

Restoril 30 mg

Page 59: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Just Your Typical FDA Certified Manufacturing Laboratory

Page 60: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

                      

Turning this……………….into this.

Page 61: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy
Page 62: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

'Skittling' New Drug Of Choice For Some Teens: Product Sold On Store Shelves

October 22, 2003

Ingredients:

Dextromethorphan

Chlorpheniramine Maleate

Page 63: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Other Products Containing Dextromethorphan

                                          

Page 64: “The Faces of Substance Abuse in America” It’s Ugly and Getting Uglier by Paul L. Doering, M.S. Distinguished Service Professor, Emeritus College of Pharmacy

Buying Dextromethorphan in Bulk