V sao nhm quinolon k dng cho tr em? Gii thch?Khng sinh nhm
quinolon: ng kinh c th xy ra khi iu tr bng cc khng sinh nhm
quinolon. Do vy, nhm khng sinh ny nn c s dng mt cch thn trng trn
nhng bnh nhn c hay ang nghi ng c cc bnh l h thn kinh trung ng. Khis
dng trn nhm bnh nhn ny, cc quinolon c th lm khi pht ng kinh hay h
thp ngng ng kinh. Phn ng h thn kinh trung ng cng c th xy ra ngay
khi dng quinolon liu u tin. iu tr bng quinolon cng i khi gy trm cm
hoc ri lon tm thn c th tin trin n gy hnh vi nguy him cho bn thn v x
hi. Vim gn v t gn (thng l gn Achille) c th xy ra khi iu tr bng
quinolon, c bit trn bnh nhn ln tui v nhng bnh nhn ang iu tr hoc trc
iu tr bng glucocorticoid. Khi c nhng du hiu u tin ca au hay vim,
phi ngng thuc ngay v bt ng chi b nh hng. Quinolon c th gy cc phn ng
nhy cm vi nh sng. Do , bnh nhn ang iu tr bng quinolon nn trnh tip
xc trc tip vi nh sng mt tri hoc tia cc tm. Nn ngng iu tr nu c xut
hin ban hay phng rp trn da. Ngay c khi s dng thuc theo n, quinolon
vn c th nh hng n tc phn x n mc lm gim kh nng li xe hoc vn hnh my
mc, c bit l khi c ung ru km theo. Tc dng ph thng thy trn tiu ha do
quinolon l: nn, bun nn, au thng v, cm gic nng d dy. Vi t chc sn,
quinolon nh hng n s pht trin ca sn ti cc khp chu lc do chng ch nh
cho ph n c thai v tr em trong tui pht trin (di16 tui). Vi h hp,
quinolon c th gy ngng th khi tim hoc truyn tnh mch.Vi cc sulfamid:
nhm thuc ny ch c dng hn ch vi cc ch nh iu tr mi. Tc dng khng mong
mun ch yu bao gm:- Biu hin nhy cm: xy ra sau 5-7 ngy (pht ban, nga,
my ay, vim qung, bng nc, bong biu b, au khp, kh th dng hen, vim cu
thn, vim k thn).- V mu, gim bch cu, thiu mu tan mu cp tnh.- V gan,
vng da (do sulfamid y bilirubin khi lin kt vi protein), c th gy bin
chng thn kinh do cm dng sulfamid cho tr s sinh. Vi tiu ha, gy chn
n, bun nn, nn, tiu chy.Vi thn kinh, lm mt ng, mt mi, nhc u.
Sulfamid cng c th gy c ch min dch v d dng thai nhi.Theo thc nghim
trn sc vt cn non thy m sn b hu hoi cho nn khng dng cho tr em di 18
tui, ph n c mang v ang nui con b. Khng dng cho ngi thiu G6PD. Ni
lun cho n vung l G6PD l glucose-6-phosphate. DY HC DC Online chia s
vi cc bn cch s dng thuc an ton hp l khi kt hp thuc vi nhm khng vim
corticosteroid.Chnh vic lm dng thuc khng vim iu tr cc bnh l trn th
trng ang mc bo ng , trnh c cc tng tc do kt hp thuc nhm ny xin c v d
hot cht PREDNSOLON :KHI S DNG HOT CHT THUC PREDNISOLON CN LU TNG TC
THUC S XY RA KHI KT HP VI CC HOT CHT SAU;1.Actazolamid; tng nguy c
giam kali huyt i khang vi tc dung li tiu.2.Acid acetylsalicylic ;
Tng nguy c chay mau da day rut ,prednisolon lam giam nng salicylat
trong huyt tng.3. Amilorid ; i khang vi li tiu .4.-Amphotericin ;
Tng nguy c giam kali huyt5.Atenolol , Captopril: i khang vi tac
dung giam huyt ap6. Carbamazepin; Tng nhanh chuyn ha prednisolone (
gim tc dng)7.Digoxin:Tng nguy c gim kali huyt --8.Erythromycin: Tng
nguy c chuyn c ch ha prednisolon9.Ipuprofen ;Tng nguy c chy mu d dy
-rut10.Levonorgestrel lm tng nng prednisolon trong huyt
tng11.Metformin ;i khng vi tc dng gim glucose huyt12.Salbutamol
;tng nguy c gim kali huyt nu dng Prednisolon-13.Theophylin ;tng
nguy c gim kali huyt14.Glycery trinitrat: i khng voi tc dng gim
huyt p15.Hydroclorothiazid: i khng vi tc dng li tiu16.Methotrexat;
Tng nguy c c tnh huyt hc17.Nifedipin ;i khng vi tc dng gim huyt
p18. Phenobarbital; Chuyn ha prednisolon tng nhanh ( gim tc dng
)19, Phenytoin; Chuyn ha prednisolon tng nhanh ( gim tc dng )20,
Thuc trnh thai dng ung ;Lm tng nng prednisolon trong huyt tng21
.Rifampicin;Chuyn ha prednisolon tng nhanh (gim tc dng )22.
Warfarin ;Tc dng chng ng mu c th b thay i NGHA CA VIC TNG TC
THUCThy thuc dng thuc phi hp vi mc ch-Lm tng tc dng ca thuc-Lm gim
tc dng khng mong mun ca thuc iu tr-Gii c (thuc i khng ,thuc thi tr
,gim hp thu .trung ha)TUY NHIN NU KHNG HIU R TC DNG PHI HP ,THY
THUC C TH LM GIM TC DNG IU TR HOC TNG TC DNG C CA THUC Theo cc bn
thun tin cho vic bn hng v ph hp vi tiu chun GPP th nn thit k t
thuc, quy thuc (chiu cao, chiu rng, chiu su v khong cch gia cc t) v
b tr mt bng nh thuc nh th no cho hp l? 1.Vic thit k t quy phi theo
ch s nhn trc hc chiu cao, tm vi ca ngi bn hng.2.KT quy cao 100-105
cm, su 38cm, di ty theo mt bng nhng khng nn di hn 200cm.3.KT t thuc
cao 195-210cm, su 30cm, di 110-120cm cc bn khng nn ng t di qu kh di
chuyn, khong cch chia t 28-30cm gia mi t c th b tri thm 1 t lng.4.
Khong cch t quy n t 100-120 cm5.Nn b tr t quy theo hnh mng nga tn
dung ti a khng gian tip xc vi khch, hoc b tr bn phi theo chiu t ca
vo s thun theo chiu nhn ca khch. - Hiu v chnh bn thn mnh (ma trn
SWOT rt hu hiu).- Hiu bit v cng ty (nhng thng s v phn cng, p mm:
thnh lp, gi tr ct li, sn phm, i th cnh tranh.....).- Cc k nng mm
phi c.- Vn na l hu nh NTD ca cty chuyn nghip u hi:+ A (C) c xut hay
c tng g cty lun pht trin khng?+ A (C) thy mc lng nh vy c hp l ko
hay Theo a (c) vi mc cng vic nh th, lng bao nhiu l hp l.Tm li phng
vn xin vic l bc u tin trong vic BN CHNH MNH CHO CNG TY(ni chnh xc
hn l BN SC LAO NG) nn b phi nu bt c th mnh ca b trn nn hiu bit.i
xin vic ging y nh i mua vy, phi p ng c nhu cu hoc mong mun ca mnh m
phi hp ti tin th m mi b tin ra mua, NTD cng nh th y. 1. Hiu bit v
cng ty: mt s bit dc m cng ty ang c bn ti VN. Cn phn bit gia mt s
cng ty bn hng brandname (nh Sanofi, Pfizer) v hng generic (nh
United Pharma). Cc mng thuc m cng ty ang kinh doanh: thuc tr tiu
ng, huyt p, khng sinh, ...2. Hiu bit v cng vic trnh dc: bit c th no
l trnh OTC v trnh ETC. Nu bn xin vo cc cng ty a quc gia th hu ht l
trnh ETC c. C th cn hiu cht t v trnh dc, hoc hnh dung ra c nhng g
mnh s lm. V iu ny th ch c th hc hi t cc anh (ch) i lm thi.3. C d nh
pht trin bn thn trong tng lai, s theo hng Sales hay Marketting hay
CRA (Clinical Research Assistant).4. Cn chun b k nng giao tip, k
nng PR (qung co sn phm), k nng thuyt phc ngi khc, k nng sp xp qun
l, k nng lm vic nhm. C th khi phng vn, NTD s a cho bn 1 s tnh hung
yu cn bn a ra cch x l hoc c th a ra tnh hung thc t xem k nng ca bn
(nh bn th thuyt phc NTD mua 1 cy vit no hoc cho bn ng vai TDV th
gii thiu v sn phm ca mnh vi bc s).
