70
1 General Concepts - I

1st yr-qbank-2071

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General Concepts - I

2

2071/7 [New Course]

Candidates are required to give their answers in their own words as far as practicable.

The figures in the margin indicate full marks.

Use separate answer copy for each group.

Attempt all the questions.

Use separate answer copies for each group.

Group A (Anatomy)

1. Classify bone. Define osteon. 3+2=5

2. Differentiate between a skeletal muscle and smooth muscle 4

3. Draw a neat labeled diagram of a multipolar neuron. Define neuralgia. 3+2=5

4. Write short notes on: a) Structure of human chromosome b) Oogenesis 3x2=6

Group B (Physiology)

5. Describe the transport processes that occur across the cell membrane with examples.

What happens to RBCs when suspended in hypotonic & hypertonic solution? 4+2=6

6. Write short notes on: 3.5x4=14

a) Ionic basis of RMP of skeletal muscle

b) Importance of negative feedback mechanisms in homeostasis

c) Differences between ECF and ICF

d) Functions of gap junctions, rough endoplasmic reticulum and golgi apparatus

Group C (Pharmacology)

7. Classify routes of drug administration. Mention advantages and disadvantages of oral

route. 2+2+2=6

8. What is pharmacodynamics? Describe various mechanisms of drug action with an

example each. 1+5=6

9. Describe various ways by which you can calculate the dose for children. 2+2=4

10. What are the possible interactions when two drugs are administered simultaneously?

Explain your answers with examples. 2+2=4

Group D (Pathology)

11. Define edema. Describe the causes of edema. 1+3=4

12. Define hypersensitivity. Describe the mechanism of Type I hypersensitivity. 1+3=4

13. Write short notes on: 3x4=12

Bachelor Level/BDS/First Year Time: 4 hours

IBMS-General Concepts I Full Marks: 120

3

a) Oncogenic viruses

b) Pathogenesis of HIV infection

c) Coagulative necrosis

d) Metaplasia

Group E (Biochemistry)

14. Explain co-enzyme with examples. Describe isoenzyme of alkaline phosphatase along

with its significance. 2+2=4

15. Explain reducing and non-reducing carbohydrate with examples. 2+2=4

16. Write short notes on: 3x4=20

a) Glycolytic pathway

b) Lipid classification

c) Fats soluble vitamin

d) Essential amino acids

Group F (Microbiology)

17. Describe principle of Gram’s staining. 5

18. Define sterilization. Describe principle of autoclave. 1+4=5

19. List out: 2x5=10

a) Two virulence factors of bacteria

b) Two methods to bring antigen-antibody reaction in vitro

c) Two infection prevention procedures

d) Two beneficial roles of normal flora

e) Two differences between bacteria and viruses

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2070/8 [New course] Group “A” (Anatomy)

1. Describe the morphology of a synovial joint in brief. 4

2. Classify epithelium and mention its distribution. 4

3. Explain spermatogenesis in brief. 4

4. Write short notes on: 4x2=8

a) Autosomal recessive disorder

b) Derivatives of surface ectoderm

c) Parts of long bone

d) Dermis

4

Group B (Physiology)

5. Define homeostasis and explain its significance by giving examples of negative and

useful positive feedback mechanism. 1+4=5

6. Define the following terms: excitability, depolarization, repolarization, threshold

stimulus and chronaxie. Explain the ionic basis of the resting membrane potential of

a neuron. 2.5+2.5=5

7. Mention the functions of proteins present in cell membrane. Give two examples

each of inter-cellular connections and inter-cellular communication. 2+3=5

8. Write short notes on: 2.5x2=5

a) Functions of golgi apparatus and endoplasmic reticulum

b) All-or-none law and refractory period of neuron

Group C (Pharmacology)

9. Describe various process of drug elimination through kidney. Explain how you can

facilitate renal elimination of the drug by administering other drugs? 2+2+2=6

10. Enumerate parenteral routes of drug administration with examples. Mention

advantages and disadvantages of subcutaneous route. 2+2+2=6

11. Compare competitive and noncompetitive antagonists with examples. 4

12. Mention various types of hypersensitivity reactions along with the most appropriate

drug to treat particular hypersensitivity reactions 4

Group D (Pathology)

13. Define apoptosis. Describe the causes of apoptosis. 4

14. Describe the different stages in cutaneous wound healing. 4

15. Write short notes on:- 3x4=12

a) Edema

b) Chemical carcinogens

c) Type III hypersensitivity

d) Infarction

Group E (Biochemistry)

16. Sketch (Outline) of TCA cycle. Explain energy production of TCA cycle. 4+2=6

17. What are isoenzymes? Describe isoenzyme and clinical importance of LDH and ALP.

2+2+2=6

18. Write short notes on:-

a) Essential fatty acids

5

b) Physiological role of Vitamin D

c) Genetic code

Group F (Microbiology)

19. Draw a well labeled diagram of a bacterium showing its different anatomical parts.

7

20. Write down principle of Gram’s stain. 6

21. Define sterilization. Mention any one method used for sterilization of the following.

7

a) Nutrient agar b) Glass syringe c) Operation theatre

d) Apron e) Paraffin oil

**********************************************

2070/8 [Old course]

Candidates are required to give their answers in their own words as far as practicable.

The figures in the margin indicate full marks.

Use separate answer copy for each group.

Attempt all the questions.

Group A (Anatomy)

1. Write short notes on: 4x8=32

a) Fibrous joint

b) Haversian system

c) Derivative of neural crest cells

d) A multipolar neuron

e) Autosomal dominant disorder

f) Structure & Functions of mature placenta

g) Appendages of skin

h) Classification of gland

Group B (Physiology)

2. Draw a labeled diagram of the cell membrane and describe the various transport

processes occurring across it. 3+5=8

Bachelor Level/BDS (I Year)/ IOM Time: 3 hours

IBMS-General Concepts I Full Marks: 160

6

3. Draw a labeled diagram of an action potential of a neuron and explain the ionic basis.

Explain all or none phenomenon and refractory period. 5+3=8

4. Describe the composition and volume of different body fluid compartments in an

adult. Shed light on the functions of the plasma proteins. 5+3=8

5. Write short notes on:- 4x2=8

a) Classification of sensory receptors

b) Negative feedback mechanisms and their importance

Group C (Pharmacology)

6. Classify topical routes of drug administration. Mention advantages and disadvantages

of inhalation route. 3+2+2=7

7. Mention the various consequences of drug metabolism with examples. Name any

four microsomal enzyme inhibiting drugs. Describe their interactions with

concurrently used drug undergoing same metabolic reaction. 3+2+2=7

8. Define adverse drug reaction. Mention eight varieties of adverse drug reactions with

examples of any four of them. 1+4+2=7

9. What is therapeutic drug monitoring? Mention indications & limitations of

therapeutic drug monitoring. 1+3+2=6

10. Explain the precautions to be taken while using drugs during pregnancy. List any six

highly teratogenic drugs that should be barred during pregnancy. 2+3=5

Group D (Pathology)

11. Define necrosis. List different types of necrosis. Describe about coagulative necrosis.

1+1+3=5

12. Describe the vascular changes in acute inflammation. 5

13. List different types of emboli. Describe briefly about pulmonary embolism. 2+3=5

14. Define hypersensitivity. Describe about type I hypersensitivity. 1+4=5

15. Write short notes on: 3x4=12

a) Atrophy

b) Septic shock

c) Disseminated intravascular coagulation

Group E (Biochemistry)

16. Sketch the pathway of glycogenesis and mention various glycogen storage diseases.

3.5+1.5=5

17. Explain competitive and uncompetitive types of enzyme inhibition with examples.

2.5+2.5=5

7

18. Write short notes on: 3x2=6

a) Monosaccharide

b) Essential amino acids

c) Physiological role of Vit. A

Group F (Microbiology)

19. Define sterilization. Classify methods of sterilization. 5

20. What are the beneficial roles of normal flora? Give two examples of normal flora of

oral cavity. 5

21. Give 3 examples of gram positive and gram negative bacteria. 6

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2069/9[New Course]

Group A (Anatomy)

1. Mention briefly the important events that occur during grastulation. 4

2. Compare the characteristic features of autosomal dominant and autosomal recessive

traits. Give few examples of reach type of disease. 4=1=5

3. Describe the morphology of synovial joint. Classify synovial joint. 3+2=5

4. Write short notes on: 3x2=6

a) Histology of epidermis

b) Parts of long bone

Group B (Physiology)

5. Define homeostasis and give examples of negative and positive feedback control

mechanisms. What is vicious cycle? 4

6. Enumerate the cellular organelles and explain the functions of any three organelles.

4

7. Define reflex and draw a reflex arc. Mention the functions of the different

components of a reflec arc. 4

8. Write short notes on: 2x4=8

a) Colloid osmotic pressure

b) ECF compartment

c) Depolarization and repolarization

d) Paracine communication

8

Group C (Pharmacology)

9. Define essential drugs. Mention the criteria for selecting essential drugs. 2+4=6

10. Enumerate (with examples) any 6 factors that modify the action of drugs. 6

11. What do you mean by antagonist? Mention types of receptor antagonists each with

an example. 1+3=4

12. What is entero-hepatic circulation? Mention its consequence on the effect of a drug.

Give example of a drug that undergoes entero-hepatic circulation. 2+1+1=4

Group D (Pathology)

13. List the chemical mediators and write down their role in inflammation. 4

14. Define thrombus. Describe the different types of thrombi. What are the fates of the

thrombus? 4

15. Write short notes on: 3x4=12

a) Type II hypersensitivity

b) Tumor suppressor genes

c) Amyloidosis

d) Edema

Group E (Biochemistry)

16. Explain the classification of carbohydrate with examples. 5

17. Give outline of TCA cycle and list the inhibitors of TCA cycle. 4.5+1.5=6

18. Write short notes on: 3x3=9

a) Fat soluble vitamins

b) Compound lipids

c) Funtions of nucleotides

Group F (Microbiology)

19. Define anaerobes. Differentiate between exotoxin and endotoxin 2+6=8

20. List out the beneficial and harmful roles of normal flora. 2.5+2.5=5

21. Give two examples of gram positive and gram negative bacteria. 0.5x4=2

22. Mention any one method used for sterilization of the following. 5

a) MacConkey agar

b) Inoculating loop

c) Beaker

d) Apron

9

e) Plastic syringe

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2068/3

Group “A” (Anatomy)

1. Classify muscle with example. Describe briefly on skeletal muscle. 2+4=6

2. Describe brief the process from fertilization to implantation. Mention some related

applied aspects. 4+2=6

3. Classify bone with appropriate examples. 6

4. List the differences between myelinated and non-myelinated nerve fiber. 6

5. Write short notes on: 4x2=8

a) Mendelian trait

b) Morphology of a synovial joint

Group “B” (Physiology)

6. Define homeostasis and explain with examples why homeostasis is important for

normal body function. 2+4=6

7. Enumerate the cellular organelles and describe the functions of any two organelles.

3+3=6

8. Write short notes on: 4x5=20

a) Definition and classification of reflexes

b) Depolarization and repolarization of a neuron

c) Cell membrane structure and its functions

d) Osmosis and colloid osmotic pressure

e) Functions of platelets and erythrocytes.

Group “C” (Pharmacology)

9. What do you mean by therapeutic drug monitoring (TDM)? Mention where TDM is

advised and where TDM is not required. 1+3+3=7

10. What is half life of a drug? Mention various factors that determine the duration of

drug action. 1+5=6

11. Define ADR (adverse drug reaction). Describe any six ADRs with an appropriate

example of each. 1+6=7

12. Write short notes on: 4x3=12

a) Biotransformation

b) Drug use in pregnancy

c) Antagonism

10

Group “D” (Pathology)

13. Define edema. List the causes of edema. 4

14. Define neoplasm. Explain the mechanism of spread of malignant tumors. 6

15. Describe the different steps in wound healing. 6

16. Write short notes on: 4x4=16

a) Type III hypersensitivity

b) Septic shock

c) Coagulation necrosis

d) Thrombosis

Group “E” (Biochemistry)

17. Sketch the outline of glycolysis. Explain the regulation of TCA cycle. 4+2=6

18. Enumerate and mention the functions of essential fatty acid and essential amino

acid. 1+3=4

19. Write short notes on: 2x3=6

a) Classification of lipoproteins

b) Properties of rRNA and tRNA

c) Classification of lipid

Group “F” (Microbiology)

20. Write difference between bacteria and virus. 4

21. Define bacterial growth. Describe different phases of bacterial growth. 4

22. Define sterilization. Describe moist heat method of sterilization. 4

23. Write short notes on:

a) Immunity

b) Gram stain

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2067/4

Group “A” (Anatomy)

1. What do you understand by a neuron? Mention the difference between myelinated

and unmyelinated nerve fibers. 3+3=6

2. What are the different types of connective tissue fibers? Where are they found?

3+3=6

3. Write short notes on: 5x4=20

11

a) Transitional epithelium

b) Spermatogenesis

c) Bilaminar germ disc

d) Gross structure of human chromosome

e) Gross features of a synovial joint.

Group “B” (Physiology)

4. Draw a mammalian cell showing different organelles. Mention the function of any

three organelles. 2+6=8

5. Define a receptor. Give a simple classification of sensory receptors with examples.

1+5=6

6. Describe different types of intercellular communication with examples. 6

7. Write short notes on: 4x3=12

a) Action potential of a neuron

b) E.C.F.

c) Negative feedback mechanism

d) Reflex arc

Group “C” (Pharmacology)

8. Define essential drug. List out four factors modifying the drug action. 2+5=7

9. Classify penicillins. Describe its’ mechanism of action and adverse effects.

2.5+2+2.5=7

10. Define adverse drug effects. Enumerate various adverse drug effects with a suitable

example of each. 1+5=6

11. Write short notes on: 3x4=12

a) Combined drug effect

b) Route of drug administration

c) Receptor

Group “D” (Pathology)

12. Define shock. Explain different types of shock. 2+6=8

13. Define neoplasia. Explain the mechanism of spread of malignant tumors.2+6=8

14. Write short notes on: 4x4=16

a) Type IV hypersensitivity

b) Wound healing by second intention

c) Calcification

12

d) Pulmonary embolism

Group “E” (Biochemistry)

15. Define glycolysis. Sketch glycolytic pathway. 1+3=4

16. a) Define isoenzymes. Explain the importance of alkaline phosphate as an isoenzyme.

1+3=4

b) Describe the physiological roles of vit. A 2

17. Write short notes on:

a) DNA duplication

b) Classification of lipid

c) Quaternary structure of proteins

Group “F” (Microbiology)

18. List four differences between bacteria and viruses. 8

19. Describe on moist heat method of sterilization with examples. 4

20. Explain the cellular immune response. 4

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2065/7

Group “A” (Anatomy)

1. Describe the morphological features of a synovial joint. Classify synovial joint with

appropriate examples. 4+4=8

2. Draw a neat and labeled diagram of microscopic anatomy of a compact bone. 8

3. Explain the gastrulation. 8

4. Write short notes on: 2x4=8

a. Placenta

b. Heredity

Group “B” (Physiology)

5. Define excitability. Name the excitable tissues. Explain the ionic basis of action

potential of a neuron. 1+1+4=6

6. Describe the functions of any three important cell organelles. 2+2+2=6

7. Explain osmosis, primary active transport, and secondary active transport with

suitable examples. 2+2+2=6

13

8. Explain how homeostasis is maintained by negative feedback mechanism. 4

9. Write short notes on: 2 ¼ x4=10

a. Saltatory conduction of action potential

b. Intracellular communication

c. Composition and volume of ECF

d. Useful positive feedback mechanisms in the body.

Group “C” (Pharmacology)

10. Define bioavailability. Explain the advantages and disadvantages of intravenous route

of drug administration. 2+6=8

11. Write short notes on: 3x4=12

a) Tolerance

b) Agonist and antagonist

c) Receptor and its types

d) Bio-equivalence

12. Explain the following terms: 3x4=12

a) Prodrug

b) Methods of dose calculation in children

c) Plasma half life

d) Teratogenicity

Group “D” (Pathology)

13. List the important chemical mediators of acute inflammation and their role in

inflammation. 6

14. Describe the different stages in wound healing. 6

15. Define shock. Describe the pathogenesis of septic shock. 1+5=6

16. Describe the mechanism of type III hypersensitivity. 6

17. Write short notes on: 4x2=8

a) Apoptosis

b) Pulmonary thromboembolism

Group “E” (Biochemistry)

18. Define isoenzymes and list clinically important isoenzymes of LDH. Explain the clinical

importance of CPR. 1+2+2=5

19. Describe TCA cycle (outline only, no description). Also mention the energy production

in TCA cycle. 4+1=5

20. Write short notes on: 3x2=6

14

a) Water soluble vitamins

b) Characteristic feature in the process of transcription

c) Essential fatty acids

Group “F” (Microbiology)

21. Describe morphology & structure of bacterial cell with the help of neat diagram.

8

22. Write short notes on: 4x2=8

a) Sterilization

b) Nosocomial infection

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2064/8

Group “A” (Anatomy)

1. What do you understand by a neuron? Mention the differences between myelinated

and unmyelinated nerve fibers. 3+3=6

2. Mention the microscopic features of a cardiac muscle. Why is it called a functional

syncitium? 3+1=4

3. Mention the layers forming placental barrier of a mature villus. Mention the

functions of placenta. 2+4=6

4. Mention briefly: 8x2=16

a. Down syndrome b. Autosomal dominant diseases

c. Gomphosis d. Hyaline cartilage

e. Periosteum f. Walls of a muscular artery

g. Capacitation h. Layers of epidermis

Group “B” (Physiology)

5. Define an action potential of a neuron and mention the ionic basis of its different

phases. Illustrate the conduction of an A. P. along a myelinated neuron.

4+2=6

6. Explain with two examples the negative feedback control of homeostasis. 6

7. Name the different fluid compartments and give their volumes in an adult. Tabulate

the important constituents of the fluid compartments. 3+3=6

8. Describe the transport mechanism occurring across a cell membrane. 6

9. Write short notes on: 4x2=8

15

i. Oncotic pressure

ii. Reflex arc

iii. Intercellular communication

iv. Lysosomes

Group “C” (Pathology)

10. Define the terms carcinoma and sarcoma with appropriate examples. What are the

four characteristic features of malignant tumors? Enumerate three pathways of

spread of malignant tumors with an example of each. 2+2+2=6

11. What is granuloma? Enumerate four causes of granulomatous inflammation.

Enumerate microscopic features of tuberculous granuloma. 1+2+3=6

12. What is wound healing by primary intention? Mention briefly the steps of wound

healing by primary union. 1+5=6

13. Define type II hypersensitivity. Give four examples of antibody mediated diseases.

List the types of immunodeficiency states. 1+2+1+2=6

14. Define dystrophic and metastatic calcification. Enumerate four examples of

immunodeficiency states. 2+2=4

15. What is endotoxic shock? What are the effects of shock on kidneys and in the lungs?

4

Group “D” (Pharmacology)

16. Define the following terms: 4x4=16

a. Pharmacodynamics b. Bioavailability

c. First pass metabolism d. Half life

17. Enumerate advantages and disadvantages of parenteral drug administration. 8

18. Enumerate factors modifying drug actions. 8

Group “E” (Biochemistry)

19. Explain different kinds of inhibition of enzymes. 4

20. Sketch the pathway of gluconeogenesis 4

21. List the active terms of vitamin A, D, E and K. 2

22. Write short notes on: 3x2=6

a. DNA duplication

b. Essential fatty acids

c. Primary and secondary structure of proteins.

Group “F” (Microbiology)

16

23. Define sterilization. Explain the types of sterilization. 1+2=3

24. Define immunity. Explain the types of immunity. 1+2=3

25. Define anaerobe. Give two examples of anaerobes. 2

26. Write short notes on any TWO: 4x2=8

a. Immunoglobins and their types

b. Antibiotic susceptibility testing

c. Microbial normal flora.

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2063/8

Group “A” (Anatomy)

1. Explain neurulation. 4

2. Mention placenta and its functions. 4

3. Explain chromosomal non-dysjunction and Down’s syndrome. 4

4. Classify exocrine gland with appropriate examples. 4

5. Mention microscopic features of hairy skin. 4

6. Explain gross features of a synovial joint. 4

7. Explain the principles of Mendelian inheritance. 4

8. Explain the classification of cartilage with examples. 4

Group “B” (Physiology)

9. Define homeostasis. Give examples of negative and positive feedback mechanisms.

1+3=4

10. Define an action potential. Give the ionic basis of its depolarization, repolarization

and after hyperpolarization. 1+3=4

11. Draw a labeled diagram of mammalian cell. Name the functions of the cell

membrane. 2+2=4

12. Explain facilitated diffusion and active transport with examples. 2+2=4

13. What are the forces operating at the capillary level? 4

14. Write short notes on: 4x2=8

a. Functions of plasma proteins

b. Factors regulating erythropoiesis

c. Functions of platelets and eosinophils

d. Rh incompatibility

17

Group “C” (Pathology)

15. Define necrosis. Describe different types of necrosis. 6

16. Define briefly cellular events in acute inflammation. 6

17. Describe the wound healing by secondary intention. 6

18. Define embolism. List different types of emboli. 1+3=4

19. List primary and secondary mediators in type I hypersensitivity reaction. 4

20. Describe briefly about chemical carcinogenesis. List important chemical carcinogens.

4+2=6

Group “D” (Pharmacology)

21. Define drug. Describe various aspects of pharmacokinetics. 8

22. Describe various routes of drug administration with their specific features. 8

23. Write short notes on: 4x4=16

a. Pharmacodynamics

b. Rational drug therapy

c. Drugs contraindicated in pregnancy

d. Therapeutic drug monitoring

Group “E” (Biochemistry)

24. Write short notes on: 4x2=8

a. Physiological role of vitamin E and K

b. Characteristic feature in process of transcription

c. Essential fatty acids

d. Primary structure of proteins.

25. Describe TCA cycle. 5

26. List the biochemical investigation of diabetes mellitus. 3

Group “F” (Microbiology)

27. Write the difference between eukaryotic and prokaryotic cell. 10

28. Write morphological classification of bacteria with at least one example of each type.

6

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2062/7

Group “A” (Anatomy)

1. Define a gland and give its classification. Describe in brief the exocrine gland with

appropriate examples. 2+4=6

18

2. Describe skin under the following headings: 2+2+2=6

a. Different layers

b. Appendages

c. Function

3. Write short notes on: 4x5=20

a) Spermatogenesis

b) Bilaminar germ disc

c) Transverse section of umbilical cord

d) Developmental anomalies of placenta

e) Gross structure of human chromosome

Group “B” (Physiology)

4. Explain nerve impulse conduction in a myelinated and non-myelinated neuron. Name

two factors that influence velocity of conduction. 3+1=4

5. Define bleeding and clotting time and give their normal values. What happens in

thrombocytopenic purpura? 3+1=4

6. Define homeostasis. Give an example of positive and negative feedback mechanisms.

1+3=4

7. Explain primary and secondary active transport mechanisms with examples. 2+2=4

8. Name the plasma protein. Give the value of colloid osmotic pressure and mention its

functions. 1+3=4

9. Explain the role of iron, erythropoietin, vitamin B12 and folic acid in erythropoiesis.

Why does polycythaemia occur in high altitude? 4+2=6

10. Give the normal values of TLC, DLC and ESR. Mention any two functions of

neutrophils and eosinophils. What factor influence ESR? 2+2+2=6

Group “C” (Pathology)

11. Define necrosis. List different types of necrosis. Describe briefly about coagulation

necrosis. 1+1+2=4

12. Describe about vascular changes in acute inflammation. 6

13. Describe the mechanism of type I hypersensitivity reaction. 6

14. Define shock. Explain different types of shock. 4

15. Describe the mechanism of edema in heart failure. 6

16. Describe different steps in wound healing. 6

19

Group “D” (Pharmacology)

17. Define drug. List advantages and disadvantages of parenteral routes of drug

administration. 2+6=8

18. Describe different hazards with use of drugs in pregnancy. 8

19. Write short notes on: 4x4=16

a. Plasma half life

b. Drug antagonism

c. First pass metabolism

d. Drugs use in renal diseases

Group “E” (Biochemistry)

20. List the main functions of lysosomes and golgi apparatus. 2

21. List neutral and acidic amino acids. 2

22. Describe the classification of lipoprotein. 2

23. Explain the chemical importance of CPK as isoenzyme. 2

24. Write short notes on: 2x4=8

a. Glycogenolysis

b. Physiological role of vitamin A and D

c. Properties of RNA and tRNA

d. Biochemical investigation in diabetes mellitus

Group “F” (Microbiology)

25. Describe how you differentiate between prokaryotes and eukaryotes.3+3=6

26. Define sterilization. How do you sterilize the following: 3x2=6

a) Surgical glove

b) Nutrient broth

c) Petridish

27. Define immunity. Give an example of artificially acquired active immunity. 2+2=4

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2061/7

Group “A” (Anatomy)

1. Mention the developmental sources of skin. Draw a labeled diagram to represent the

different layers of epidermis. 1+3=4

2. Mention different parts of chromosomes and their types. 2+2=4

20

3. Write short notes on: 4x3=12

a. Bilaminar germ disc

b. Transitional epithelium

c. Primitive streak

4. Mention different types of membranes present in our body. Give examples of each

type. 4

5. Define the following: 4x2=8

a) Flexion

b) Adduction

c) Coronal section

d) Circumduction

Group “B” (Physiology)

6. Draw a labeled diagram of nerve action potential. Give the ionic basis of the different

phases of the action potential. How is nerve impulse conducted? 3+2+2=7

7. Define homeostasis? Explain the positive and negative feedback mechanisms with an

example for each feedback. 1+2+2=5

8. Write short notes on: 5x4=20

a) Diffusion and osmosis

b) Mitochondria

c) Neuroendocrine reflex

d) Cell membrane structure

e) Factors regulating erythropoiesis

Group “C” (Pathology)

9. Define thrombosis. Describe the morphology of different types of thrombus. 2+6=8

10. Define neoplasia. Explain mechanism of spread of malignant tumors. 2+6=8

11. Define inflammation. Explain vascular changes and cellular events of acute

inflammation. 2+6=8

12. Write notes on: 2x4=8

a. Edema b. Embolus

Group “D” (Pharmacology)

13. Explain the precautions to be taken while using drugs in pregnancy. 6

14. Define: 5x2=10

a. Bioavailability

b. First pass metabolism

c. Antagonism

21

d. Therapeutic index

15. Write short notes on: 4x2=8

a. Therapeutic window

b. Mechanism of action of drugs

c. Drug potency

d. Drugs use in liver disease

16. Describe the therapeutic significances of the followings: 4x2=8

a. Dose response relationship

b. Plasma half life

c. Therapeutic drug monitoring

d. Different routes of drug administrations.

Group “E” (Biochemistry)

17. Classify enzymes with examples. List co-enzymes, which take part in dehydrogenation

and trans-amination reaction. 4+2=6

18. Explain in brief the reactions and products of glycolytic pathway with illustration of

enzymes involved. 6

19. Enumerate and mention the functions of essential fatty acids. 2

20. List the amino acids which are both glycogenic and ketogenic. 2

Group “F” (Microbiology)

21. Differentiate between eukaryote and prokaryote. 5

22. Define culture media. List any three routine media used in clinical bacteriology. 5

23. Describe principal of Gram’s stain. 6

**********************************************

2061/1

Group “A” (Anatomy)

1. Draw a labeled diagram of the structure of a mature spermatozoon. Add a note on

spermatogenesis. 4+4=8

2. Define epithelium. Mention different types of epithelia with their characteristic

features and examples. 2+6=8

3. Write short notes on: 2x4=8

a) Synovial membrane

b) Placenta

4. Answer the following: 4x2=8

a) Classify the joints of human body. Give examples of each variety.

22

b) Define tissue and describe the classification of tissue.

Group “B” (Physiology)

5. a) Define reflex 2

b) Enumerate different types of reflex. 3

c) Mention the properties of reflex. 3

6. Define membrane potential. Mention the process of generating membrane potential.

2+6=8

7. a) Define carrier system. 2

b) Mention the different types of carrier system and give description with examples.

3+3=6

8. Enumerate the body fluid spaces. Describe the distribution of body fluid. Mention the

functions. 3+3+2=8

Group “C” (Pathology)

9. Define necrosis. Describe different types of necrosis. 1+4=5

10. Define hypersensitivity. Describe the mechanism of type II hypersensitivity reaction.

1+4=5

11. Define shock. Give the classification of shock. Describe briefly the pathogenesis of

shock. 1+2+5=8

12. Define embolism. List different types of embolism. 1+3=4

13. Differentiate benign and malignant tumors. 6

14. List the different chemical mediators of acute inflammation. 4

Group “D” (Pharmacology)

15. What is pharmacology? Enumerate the routes of drug administration, its advantages

and disadvantages. 2+7+7=16

16. Describe antimicrobial drugs depending upon its mechanism of action in microbial

cell structure. 6

17. Classify antimicrobial drugs depending upon its mechanism of action in microbial cell

structure. 10

Group “E” (Biochemistry)

18. Write the sources and fate of acetyl CoA. 6

19. List the functions of sub cellular organelles:

a. Mitochondria 2

b. Golgi apparatus 2

23

20.

a. Give the explanatory diagram sowing the process of gluconeogenesis. Give its

clinical signification. 3+1=4

b. List the functions of plasma proteins. 2

Group “F” (Microbiology)

21. Differentiate normal flora from transient flora. 2

22. Write short notes on: 2x2=4

a) Isolation media

b) Identification media

23. Differentiate moist heat sterilization from dry heat sterilization. 2

24. Define bacterial toxin. Differentiate exotoxin from endotoxin. 1+3=4

25. Write short notes on: 2x2=4

a) Gram stain

b) Selective stain

**********************************************

2060

Group “A” (Anatomy)

1. Describe the structure and the function of the cell. 8

2. Define and classify glands. 8

3. List the types of cell division and their importance. 8

4. Describe synovial membrane. 8

Group “B” (Physiology)

5. Name the excitable tissues. Explain the ionic basis of resting membrane potential. 4

6. Define homeostasis and mention its importance. Explain negative feedback

mechanism with an example. 2+2+3=7

7. Name the different stages of erythropoiesis and the factors regulating erythropoiesis.

6

8. Write short notes on: 3x5=15

a) Cell membrane structure

b) Functions of plasma proteins

c) Functions of granulocytes

Group “C” (Pathology)

24

9. Define necrosis. Name four types of necrosis. Describe the microscopic features of

any one of them. 2+4+4=10

10. Define inflammation. Name four chemical mediators of acute inflammation. List four

complications of acute inflammation. 2+4+4=10

11. Define healing. Differentiate between primary and secondary healing. 2+4=6

12. Define: 3x2=6

a. Hyperplasia

b. Hypertrophy

c. Metaplasia

Group “D” (Pharmacology)

13. State what half life is and mention its significance in dosing of a drug. State how

much of a drug of 100 mg given I.V. is left after three half life. 1+2+2=5

14. Explain the following terms with examples: 4x2=8

a. Agonist

b. Potency

15. What is biotransformation? State the types of biotransformation and explain the

microsomal enzyme induction and inhibition giving examples. 5

16. State why monitoring of a drug in plasma is necessary. 4

17. State the factors affecting the absorption of a drug given orally. 4

18. Name four types of toxicity of drugs with examples producing them. And mention a

formula for calculation of a dose for children. Also mention precautions needed in

using drugs in children. 4

19. What is the maintenance dose and how is it calculated? 2

Group “E” (Biochemistry)

20.

a. List the essential amino acids. 4

b. List the functions of proteins in the body. 4

21.

a. Give an example of disaccharide and polysaccharide. 4

b. List essential fatty acids and give an example of phospholipids and Glycolipid. 4

Group “F” (Microbiology)

22. Write short notes on:

25

a) Bacterial spores 4

b) Bacterial toxins 4

c) Sterilization by moist heat 4

d) Agglutination test 4

**********************************************

2059

Group “A” (Anatomy)

1. Define a tissue. Classify the tissues and their functions. 6

2. How many branchial apparatus are present during the development of human being?

Mention the structures derived from the first branchial apparatus. 6

3. How many chromosomes are present in human being? Briefly describe the gross

structure of human chromosome. 6

4. What is gametogenesis? Briefly explain spermatogenesis. 4

5. What is placenta? Mention the functions of placenta. 4

6. Mention the clinical features of Klinfelter’s syndrome. 2

7. Draw a labeled diagram of skin. 4

Group “B” (Physiology)

8. Define epithelial tissues. Mention the different types of epithelium with their

characteristic. Mention the distribution and functions. 2+3+3=8

9. Describe the cell membrane. Explain the process of depolarization and repolarization.

2+3+3=8

10. Define receptors. Classify receptors. Explain the process of transmission of impulse

through the synapse. 2+3+3=8

11. Enumerate the different types of reflex. Mention the properties of reflex. 3+5=8

Group “C” (Pathology)

12. Briefly describe the morphology of reversible cell injury. 6

13. Define metaplasia and dysplasia. 2+2=4

14. Briefly describe the cellular events in acute inflammation. 6

15. Briefly describe the mechanism of type I hypersensitivity reaction. 6

16. Define embolism. List out different types of emboli. 1+3=4

17. Briefly describe the mechanism of spread of malignant tumor. 6

26

Group “D” (Pharmacology)

18. What do you mean by sublingual administration of drug? How will you evaluate the

sublingual administration? 5

19. What are the processes of drug administration? 9

20. What are precautions that should be taken in using drugs in old people? 5

21. What is meant by teratogenic effect? List the drugs having teratogenic effect. 5

22. Define these terms: 4x2=8

a. First pass metabolism

b. Bioavailability

c. Idiosyncrasy

d. Biological half life

Group “E” (Biochemistry)

23.

a. List the physiological functions of vitamin A and give two examples of deficiency

disease as well as effects of hypervitaminosis. 2+1+1=4

b. Draw a diagram showing pathways of gluconeogenesis and mention how is it

controlled. 3+1=4

24. Define any FOUR:

a. Enzyme

b. Co- enzyme

c. Holoenzyme

d. Isoenzyme

e. Apoenzyme

Group “F” (Microbiology)

25. Show diagrammatically the difference between gram positive and gram negative

bacteria. 8

26. Classify methods of sterilization. Explain the principle of autoclave. 8

**********************************************

2058

Group “A” (Anatomy)

1. What are the types of cell division? Mention their significance. 1+5=6

2. Define a tissue. What are the different types of tissues? Mention their functions.

27

1+2+3=6

3. What are the embryonic sources of skin development? Mention its functions. What is

the clinical significance of the skin? 2+2+2=6

4. Define heredity. Describe the gross structure of human chromosome. 1+5=6

5. Short answers: 4+4=8

a) Functions of placenta

b) Umbilical cord

Group “B” (Physiology)

6. Define receptors. Mention their distribution in the body. Give their functions.

2+4+4=10

7. What is reflex? Classify reflex. Mention their properties. 2+4+4=10

8. Describe the distribution of body fluid in different compartments. Discuss the factors

regulating it. 4+4=8

9. Briefly describe the process of genesis of membrane potential. 4

Group “C” (Pathology)

10. Define inflammation. Name the agents causing inflammation. Name two functions of

neutrophil in acute inflammation. 2+4+2=8

11. Define necrosis. Enumerate the causes of necrosis. Mention the different

morphological types of necrosis. 2+2+4=8

12. Enumerate the difference between benign and malignant tumors. 6

13. Draw and label a neat diagram of tubercle. 4

14. What are giant cells? Mention the different types of giant cells. 2+4=6

Group “D” (Pharmacology)

15. What is adverse drug reaction? Mention the patients particularly in risk of adverse

drug. 2+2=4

16. What is biotransformation? Explain the phases of biotransformation in brief. 3+5=8

17. List the different parenteral routes and state advantages and disadvantages of

intravenous route. 4

18. Define the dose of a drug. State the methods of calculating the dose for children.

Calculate the dose for a child of 8 years old, the adult dose being 80mg/kg. 2+2+4=8

19. Define the following terms: 4x2=8

a. Receptor

b. Agonist

28

c. Potency

d. Efficacy

Group “E” (Biochemistry)

20. Give a short answer with example of the reaction showing co-enzyme functions of

Vit. B1 and B2. 6

21.

a. Draw a diagram showing glycogenesis.(with related enzymes) 6

b. List the functions of lysosomes, peroxysomes and nucleolus. 4

Group “F” (Microbiology)

22. Explain the characteristics of viral structure and viral replication. 3+3=6

23. Distinguish pathogens from normal bacterial flora. Explain the characteristics of

pathogenesis. 3+3=6

24. List the decontaminating agents and decontamination procedure for the infection

prevention of dental procedure. 2+2=4

**********************************************

2058

Group “A” (Anatomy)

1. What is fertilization? What is its normal site? What are its results? 6

2. What is placental membrane (barrier)? What substances can be exchanged or

transmitted through this barrier? 6

3. What is connective tissue? Classify connective tissue structurally. 4

4. Give four differences between epithelial and connective tissue and give the location

of any two types of connective tissue in our body. 6

5. Write short notes on: 2.5x4=10

a. Functions of skin

b. Notochord

c. Umbilical cord

d. Derivatives of foregut.

Group “B” (Physiology)

6. What is action potential? What is the basis of latent period? 4+1=5

7. What is diffusion? Give an example of diffusion of gases in human body. 4+1=5

29

8. What is extracellular fluid space? Illustrate your answer with suitable example.

4+1=5

9. How is body function regulated by feedback mechanism? 4+1=5

10. Enumerate the functions of blood? 4

11. List the functions of tongue? 4

Group “C” (Pathology)

12. State the important causes of inflammation. Name the cardinal signs of

inflammation. 4+2=6

13. Explain the mechanism of wound healing. 6

14. Define thrombosis. Explain the mechanism of thrombosis. 1+5=6

15. Define hypersensitivity. Name the different types of hypersensitivity reactions.

1+3=4

16. Name the different types of immunity. 4

17. Explain the types of antigen-antibody reactions. 6

Group “D” (Pharmacology)

18. Mention the different mechanisms of action of drugs giving examples for each. 6

19. State eight types of routes of administration and mention advantages and

disadvantages of I.V. route. What route is used for immediate effect in angina case?

6

20. What is bioavailability? Mention the factors affecting the absorption through oral

route. 4

21. Mention eight different adverse effects of a drug with examples. Name drugs that

have adverse effect to pregnant and lactating mother. 4

22. State what effects are produced when two drugs are given together. Mention

different types of antagonism. 4

23. State the methods of calculating the dose for children. Calculate the dose for a child

of 6 years old, the adult dose being 54mg/kg. 4

24. State the volume of distribution and factors governing it. 4

Group “E” (Biochemistry)

25. Write the sources and fate of acetyl CoA. 6

26. Describe gluconeogenesis. 6

27. Discuss the role of different types of RNA in protein biosynthesis. 4

30

Group “F” (Microbiology)

28. Give one reason: 2+2=4

a. Why viruses are not usually controlled by antibiotics

b. Why gluteraldehyde is preferable for the sterilization of some dental

equipments.

29.

a. Name two bacterial of oral microflora. 2

b. Give one reason why Salmonella species form pink colonies on Mac Conkey’s

agar medium? 2

30. Point out a main difference between cellular and humoral immunity. 2

31. Name any two bacteria causing pyaemia. 2

32. Point out the main difference between exotoxin and endotoxin. 2

33. Point out a main difference between selective and differential medium. 2

**********************************************

2057

Group “A” (Anatomy)

1. Draw a labeled diagram of a mature ovarian follicle and label its different

constituents. Mention the significance in meiosis in oogenesis. 6

2. Define placenta. What is its normal site? Explain its development. 5

3. Define tissue. Mention the different epithelial tissue and their characteristics in

Homo sapiens. 6

4. Define gland. Mention the different types of glands and their characteristics. 4

5. Enumerate -from deep to superficial- the different types of epidermis and dermis. 4

6. Explain primitive streak. 3

7. Describe the derivatives of 1stbranchial arch. 4

Group “B” (Physiology)

8. Draw a well-labeled diagram of a cell. 4+2=6

9. Describe different body fluid spaces. How does body fluid shift from one space to

another? 4+2=6

10. What is the role of feedback regulation in blood functions? 6

11. Describe the properties of cardiac muscle. 4

12. Define blood pressure. Explain pulse pressure and mean pressure. 4+2=6

31

13. Describe the composition of saliva. List its functions. 4

Group “C” (Pathology)

14. List important causes of cell injury and various changes produced in the cell by such

injury. 2+2+2=6

15. Describe the vascular phenomena of acute inflammation. 4

16. Explain the effects of embolism. 4

17. Describe the nature and types of edema. 4+2=6

18. State the differences between benign and malignant neoplastic lesions. 6

19. Define antigen, antibody and complement. 4+2=6

Group “D” (Pharmacology)

20. List the different routes of drug administration and state advantages and

disadvantages of the oral route. 6

21. Define adverse drug reaction and give six examples observed in drug reaction. 6

22. Mention the importance of drug monitoring in blood. List its indications. 4

23. Mention different ways by which the drugs or metabolites are excreted. 4

24. Draw a graph to show the potency and efficacy of drug. 4

25. What is loading dose and how is it calculated? 4

26. Mention what precautions are to be taken in using drugs to old people. 4

Group “E” (Biochemistry)

27. Explain: 3+3+2=8

a. Uncompetitive inhibitor

b. LDH as isoenzyme

c. Essential amino acids

28. Describe gluconeogenesis. 4

29. Explain DNA duplication. 4

OR

Describe the physiological role of vitamin “C”.

Group “F” (Microbiology)

30. Classify microorganism. 6

31. Describe the principle of Gram staining. 6

32. List any four gram positive and gram negative organism. 4

32

Neurosensory/

Musculoskeletal

System - II

33

2071/7 [New Course]

Ulation

Candidates are required to give their answers in their own words as far as practicable.

The figures in the margin indicate full marks.

Use separate answer copy for each group.

Attempt all the questions.

Use separate answer copies for each group.

Group A (Anatomy)

1. Trace the course and main branches of facial nerve and correlate clinically. 4+1=5

2. List the derivatives of first pharyngeal arch. 5

3. Name important nuclei and connection of thalamus. 4

4. Write short notes on: a) Masseter b)Scalp 3x2=6

Group B (Physiology)

5. Describe the mechanism of skeletal muscle contraction and explain myasthenia

gravis. Describe skeletal muscle tone. 4+1=5

6. Describe the pathway for pain sensation from the periphery to the brain. Explain the

basis of “referred” pain with examples. 3+2=5

7. Write short notes on: 2.5x4=10

a) Deep tendon reflexes

b) Functions of basal ganglia

c) Synaptic transmission

d) Effects of parasympathetic stimulation on heart and intestine

Group C (Pharmacology)

8. Classify beta blockers. Mention uses and contraindications of Propanolol. 2+2+2=6

9. Describe mechanism of action, indications and contraindications of Alprazolam.

2+2+2=6

10. Classify neuromuscular blocking agents. Describe any 4 adverse effects of d-

tubocuranine. 2+2=4

11. Enumerate disease modifying agents for management of rheumatoid arthritis.

Describe the role of glucocorticoids for treatment of rheumatoid arthritis. 2+2=4

Bachelor Level/BDS (I Year)/ IOM Time: 4 hours

IBMS-Neurosensory/Musculoskeletal System II Full Marks: 120

34

Group D (Pathology)

12. Describe the etiopathogenesis and morphology of pyogenic osteolyelitis. 2+2=4

13. Give the classification of soft tissue tumors. Describe the morphology of leiomyoma.

2+2=4

14. Write short notes on: 3x4-12

a) Basal cell carcinoma

b) Berry aneurysm

c) Gouty arthritis

d) Osteoporosis

Group E (Pathology)

15. Explain acetylcholine and snake venom. 2.5+2.5=5

16. Explain roles of PTH and calcitrol in the homeostasis of calcium and phosphate in our

body. 3+3=6

17. Write short notes on: 3x3=9

a) Muscle troponins

b) Muscular dystrophy

c) Opening of ion channels in plasma membrane

Group F (Microbiology)

18. List out the agents causing pyogenic meningitis. Describe the pathogenesis of

Neisseria meningitides. 4

19. Describe vaccines used against rabies. Write down their merits and demerits. 4

20. Write short notes on (any four): 3x4=12

a) Negri bodies

b) Herpes simplex virus

c) Toxins produced by Stapphylococcus aureus

d) Coagulase

e) Polio virus

******************************************

2070/8 [New Course]

Group A (Anatomy)

1. Mention the attachments, nerve supply and action of temporalis muscle. 4

2. Trace the course and branches of maxillary nerve with a suitable diagram. 4

3. List the derivatives of second pharyngeal arch. 4

35

4. Trace the pathway of fine touch, pressure and vibration sensation from the

periphery to the centre (brain) with suitable diagram. 4

5. Explain the histology of cornea in brief. 4

Group B (Physiology)

6. Enumerate the steps of skeletal muscle contraction and relaxation. Explain tetanic

contraction and fasciculation. 3+2=5

7. Mention the fucntions of the Basal ganglia. Explain Parkinson’s disease. 3+2=5

8. List the sensations carried by the dorsal column medial lemniscal system and trace

the pathway. Explain stereognosis and dysdiadokokinesia. 3+2=5

9. Write short notes on: 2.5x2=5

a) Deep tendon reflexes and Babinski’s sign

b) Signs of upper motor neural lesion of the facial nerve.

Group C (Pharmacology)

10. Classify competitive neuromuscular blocking agents. Mention four specific adverse

effects and four uses of Pancuronium. 2+2+2=6

11. Name four local anesthetic drugs. Describe mechanism of action and four adverse

effects of lignocaine. 2+2+2=6

12. List ocular, cardiac, respiratory and gastrointestinal effects of atropine. 4

13. Mention four uses and four specific adverse effects of Diclofenac sodium. 4

Group D (Pathology)

14. Describe the pathogenesis and morphology of Rheumatoid arthritis. 2+2=4

15. Give the classification of tumors of CNS. Describe the morphology of Glioblastoma.

2+2=4

16. Write short notes on:- 4x3=12

a) Muscular dystrophy

b) Lepromatous leprosy

c) Rhabdomyosarcoma

Group E (Biochemistry)

17. Explain functions of acetylcholine esterase. 4

18. a) Explain biological role of calcium. 2

b) Explain the role of PTH in calcium homeostasis. 4

19. Write short notes on: 2.5x4=10

a) Hypocalcaemia

36

b) Hyperpolarization and action potential

c) Neurotransmitter

d) Neurotoxins

Group F (Microbiology)

20. List out the enzymes produced by Staphylococcus aureus. 5

21. Classify Rabies vaccine. 5

22. Define meningitis. List out four causative agents of meningitis. 5

23. Give a brief account in Sabin and Salk polio vaccine. 5

**********************************************

2070/8 [Old Course]

Candidates are required to give their answers in their own words as far as

practicable.

The figures in the margin indicate full marks.

Use separate answer copy for each group.

Attempt all the questions.

Use separate answer copies for each group.

Group A (Anatomy)

1. Mention the attachments, nerve supply and action of lateral pterygoid muscle. 4

2. Mention briefly the histology of cerebellum. 4

3. Name important branches of mandibular nerve. 4

4. Describe briefly on the layers of scalp. 4

Group B (Physiology)

5. Describe neuromuscular transmission. Explain rigor mortis and myasthenia

gravis. 2+2=4

6. Classify sensory receptors with examples. Explain tactile localization and tactile

discrimination. 3+1=4

7. Write short notes on: 4x2=8

a) Signs of lower motor neuron lesion of the facial nerve

b) Functions of the hypothalamus

Bachelor Level/BDS (I Year)/ IOM Time: 3 hours

IBMS-Neurosensory/Musculoskeletal System II Full Marks: 80

37

c) Effects of parasympathetic stimulation on the heart & pupil

d) Signs of cerebellar damage

Group C (Pharmacology)

8. Describe mechanism of action of succinylcholine. Mention four specific

adverse effects of succinylcholine. 2+2=4

9. Name any four antidepressants. Mention adverse effects of amitriptyline.

2+2=4

10. List various possible interactions when two drugs are administered

simultaneously. Describe advantages of combining carbidopa with levodopa.

2+2=4

11. Enumerate four disease modifying agents used for treatment of Rheumatoid

arthritis with their mechanism of actions. 4

Group D (Pathology)

12. Give the classification of Bone tumors. Describe the morphology of osteosarcoma.

2+2=4

13. Describe different types of leprosy. 3

14. Write short notes on: 3x3=9

a) Retinoblastoma

b) Tuberculous meningitis

c) Schwannoma

Group E (Biochemistry)

15. Explain inhibitory function of snake venom. 2

16. Explain site and mode of action of calcitonin. 2

a) Fuels of skeletal muscle. 2

b) Neurotransmitter receptor. 2

Group F (Microbiology)

17. Describe morphology and staining characteristics of Staphylococcus. How do you

distinguish Staphylococcus aureus? 6

18. Write importance of KOH preparation to demonstrate fungi in skin scraping. 2

**********************************************

38

2069/1

Group A (Anatomy)

1. Name the branches and supply of mandibular nerve. 4

2. Describe the external features of medulla oblongata. 4

3. Name the muscles of mastication. Mention briefly the attachments and action of

masseter muscle. 1+3=4

4. Draw a neat labbeled diagram of histological section of a nerve (transverse

section). 4

Group B (Physiology)

5. Enumerate the important functions of the Hypothalamus. 3

6. Describe briefly neuro-muscular transmission. Explain Myasthenia gravis. 2+1=3

7. Write short notes on (any four): 2.5x4=10

a) Lower motor neuron lesion of the facial nerve

b) Isotonic muscle contraction

c) Lateral spinothalamic tract

d) ‘Fight’ or ‘flight’ response

e) Synapse

Group C (Pharmacology)

8. Explain the mechanism of action of morphine. Mention adverse effects of

morphine. 2+2=4

9. Give the basis for: a) Use of aspirin in myocardial infarction b) Use of Atropine in

organophosphorus poisoning

10. Write short notes on:

a) Alcohol

b) Phenytoin

Group D (Pathology)

11. What is pyogenic osteomyelitis? Describe its morphology. 1+3=4

12. Define rhabdomyosarcoma. Describe gross and microscopic features of

embryonalrhabdomyosarcoma. 1+3=4

13. Define cerebrovascular accident. Describe morphology of focal cerebral ischemia.

1+3=4

14. Define and describe hydrocephalus. 1+3=4

39

Group E (Biochemistry)

15. Explain with the help of suitable diagram synthesis of calcitriol. Also mention its

function. 3.5

16. Write short notes on:

a) Inhibitory function of snake venom. 2.5

b) Neurotransmitter 2

Group F (Microbiology)

17. Describe morphology, isolation and identification of Staphylococcus aureus. 4

18. Write short notes on: 2x2=4

a) Aseptic meningitis

b) Rabies

*********************************************8

2068/3

Group “A” (Anatomy)

1. Describe the origin, course and distribution of mandibular nerve. 1+1+2=4

2. Describe briefly on the attachments, nerve supply and action of Sternocleidomastoid

muscle. 2+1+1=4

3. Describe briefly the lobes of cerebral hemispheres with the appropriate diagram.

4

4. Write short notes on: 2x2=4

a) Parts of an external ear

b) Articular disc of temporomandibular joint

Group “B” (Physiology)

5. Define a synapse and mention its types. List the steps of excitatory synaptic

transmission. 2+2=4

6. Explain with examples isotonic and isometric skeletal muscle contraction.

2+2=4

7. Write short notes on: 2x4=8

a) Parkinson’s disease

b) Response of the heart and the pupil to sympathetic stimulation

c) Signs of upper motor neuron lesion

d) Motor unit and recruitment

40

Group “C” (Pharmacology)

8. List neuromuscular blocking agents. Write the mechanism of action and adverse

effects of succinylcholine. 2+2+2=6

9. Classify antiseizure drugs. Give adverse effects of phenytoin. 3+3=6

10. Write short notes on: 2x2=4

a) COX2 inhibitors

b) Salbutamol

Group “D” (Pathology)

11. Classify the bone tumors. Describe the morphology of osteosarcoma. 7

12. Write short notes on: 3x3=9

a) Meningioma

b) Muscular dystrophy

c) Melanoma

Group “E” (Biochemistry)

13. Define neurotransmitter. Outline the synthesis and degradation of acetylcholine in

myoneural junction. 1+2=3

14. List biological role of calcium. Describe physiological functions and control of PTH and

calcitriol. 2+3=5

Group “F” (Microbiology)

15. Describe the morphology of Staphylococcus. Write enzymes and toxins of

Staphylococcus aureus. 4

16. Write short notes on:

a) Coagulase test

b) Morphology of Herpes virus

**********************************************

2067/4

Group “A” (Anatomy)

1. Write short notes on: 5x3.2=16

a) Cortico-spinal tract

b) Lingual nerve

41

c) Attachments and actions of masseter muscle

d) Trace the visual pathway

e) Corpus callosum

Group “B” (Physiology)

2. Classify neurons as per their conduction velocity. 3

3. Briefly write the functions of Cerebellum. 3

4. Write short notes on: 5x2=10

a) Sarcomere

b) Motor unit

c) Functions of muscle

d) Signs of lower motor neuron lesion

e) Excitatory post synaptic potential (EPSP)

Group “C” (Pharmacology)

5. Give the basis of the use of: 3x2=6

a) Atropine in the treatment of organophosphorus poisoning

b) Multidrug therapy in treatment of leprosy

c) Lignocaine as local anesthesia

6. Give the important: 3x2=6

a) Adverse effects of phenytoin

b) Contraindications of beta-blockers

c) Uses of clozapine

7. Write short notes on: 2x2=4

a) Opoid analgesics

b) Muscle relaxants

Group “D” (Pathology)

8. Describe different types of hydrocephalus. 4

9. Give the classification of bone tumors. Describe the microscopic features of

osteoclastoma. 2+2=4

10. Describe the etiopathogenesis of gout. 4

11. Describe the morphological features of meningioma. 4

Group “E” (Biochemistry)

12. a) Explain the role of Vit. D in calcium hemostasis. 2.5

42

b) List the biological role of calcium. 1.5

13. a) Explain with example neurotransmitter. 2

b) Explain the function of acetylcholine 2

Group “F” (Microbiology)

14. Define poliomyelitis and describe on polio vaccines. 1+3=4

15. List different types of herpes virus and name one disease caused by each virus.

2+2=4

******************************************

2066/1

Group “A” (Anatomy)

1. Explain briefly the extent and course of corticospinal tract with a labeled diagram.

4

2. Name the branches and area of supply of maxillary nerve. 4

3. Write short notes on: 2x4=8

a. Attachment and action of lateral pterygiod muscle

b. Intraarticular disc of Temporomandibular joint

c. Neural tube defect and its methods of prenatal diagnosis.

d. Buccinators muscle

Group “B” (Physiology)

4. Define a synapse and list the steps of synaptic transmission. 1+3=4

5. Define a reflex. List the properties of reflex. 1+3=4

6. List the functions of hypothalamus. 4

7. Write short notes on(any TWO): 2x2=4

a. Muscle spindle

b. Saltatory conduction

c. Isotonic muscle contraction

d. E.P.S.P. and I.P.S.P.

Group “C” (Pharmacology)

8. Describe the mechanism of action and adverse effects of succinylcholine. 4

9. Describe the mechanism of action of NSAIDs. Give the major differences between

Aspirin and Paracetamol. 4

10. Give the pharmacological basis for: 4x2=8

a. Aspirin in rheumatic fever

43

b. Lignocaine for tooth extraction

Group “D” (Pathology)

11. Define osteomyelitis. List the causative organisms and write down the microscopic

features of tubercular osteomyelitis. 1.5+1.5+2=5

12. Define meningitis and enumerate the CSF finding in acute pyogenic meningitis.

2+3=5

13. List the tumors of the central nervous system. 3

14. Define stroke and list the types of stroke. 1.5+1.5=3

Group “E” (Biochemistry)

15. Define 1x3=3

a. Synapses

b. Depolarization

c. Neurotransmitter

16. Explain the role of Vitamin D in calcium phosphate homeostasis. 3

17. Explain roles of calcium. 2

Group “F” (Microbiology)

18. List organisms that cause meningitis and lab. diagnosis of meningitis. 2+2=4

19. Write short notes on Staphylococcus aureus. 4

**********************************************

2065/1

Group “A” (Anatomy)

1. Describe the Temporomandibular joint on the following headings: 4

a) Muscles causing different movements

b) Blood and nerve supply

2. Mention the origin, branches and supply of mandibular division of trigeminal nerve.

4

3. Write short notes on: 2x4=8

a) Floor of fourth ventricle

b) Foot drop

c) Digastrics muscle

d) Haversian system

Group “B” (Physiology)

44

4. Describe the mechanism of skeletal muscle contraction. What are the ways to

increase the force of contraction? 3+1=4

5. Describe the functions of the pyramidal tracts. What are the effects of upper motor

neuron lesion? 2+2=4

6. Define a synapse. List the steps of synaptic transmission. What is Renshaw cell

inhibition? 1+2+1=4

7. Write short notes on the followings: 1x4=4

a) Color blindness

b) Functions of cerebellum

c) Blood brain barrier

d) Stretch reflex

Group “C” (Pharmacology)

8. Classify NSAIDs. Write mechanism of action and clinical uses of Paracetamol.

4

9. Write short notes on:: 4x2=8

a) Clinical uses of skeletal muscle relaxants

b) Contraindications of opioid analgesics

10. Briefly discuss about the drugs used in pre-anesthetic medications. 4

Group “D” (Pathology)

11. Describe gross and microscopic features of tubercular oligo-dendroglioma. 4

12. Describe light microscopic and ultrastructural features of Guillain-Barre syndrome.

4

13. Describe gross & microscopic features of tuberculous osteomyelitis. 2+2=4

14. Write down the morphology of Paget’s diseases of bone. 4

Group “E” (Biochemistry)

15. a) List excitatory neuro-transmitters 2x2=4

b) List different fuels consumed by skeletal muscle

16. Where is parathyroid hormone produced and hoe does it act on the intestine, blood

and kidney for calcium homeostasis? 4

Group “F” (Microbiology)

17. List any four organisms causing meningitis. 4

18. Write short notes on: 2+2=4

a) Staphylococcus aureus.

45

b) Polio virus

**********************************************

2064/8

Group “A” (Anatomy)

1. List the important functional areas of cerebrum. Trace the visual pathway.4

2. Mention different parts of peripheral nervous system. Explain the typical spinal

nerve. 4

3. With labeled diagram, explain the microscopic anatomy of cardiac muscle. 4

4. Write short notes on: 2x2=4

a) Corpus callosum

b) Floor of fourth ventricle.

Group “B” (Physiology)

5. List the steps of neuro-muscular transmission. What happens in Myasthenia Gravis?

3+1=4

6. Illustrate the pyramidal tracts. Give the clinical features of lower motor neuron lesion

of facial nerve. 2+2=4

7. Enumerate the steps of skeletal muscle contraction. Give four differences in the

functional properties of smooth muscle and skeletal muscle. 2+2=4

8. Write short notes on the followings: 2x2=4

a) Spinothalamic tracts

b) Synapse

Group “C” (Pharmacology)

9. Write short notes on: 4x4=16

a) NSAIDs

b) Benzodiapines

c) Prilocaine

d) Antipyretic analgesics

Group “D” (Pathology)

10. Describe gross and microscopic features of oligodendroglioma. 4

11. Describe etiology and morphological features of gout. 4

12. Describe bony disorders caused by hyperparathyriodsism. 4

13. List the common sites of osteosarcoma. Write down different types of osteosarcoma.

46

4

Group “E” (Biochemistry)

14. Describe the role of tropomyosin and troponin complex in skeletal muscle

contraction. 4

15. Write short notes on (anyTWO): 2x2=4

a) Hyperphosphataemia causes hypocalcaemia

b) Neurotransmitter

c) Acetylcholine

Group “F” (Microbiology)

16. List any two organisms causing bacterial meningitis. Describe the methods of

laboratory diagnosis of bacterial meningitis. 1+4=5

17. Write short notes on viral meningitis. 2+2=4

**********************************************

2064/1

Group “A” (Anatomy)

1. Enumerate the muscles of facial expression. Describe the buccinator muscle.

2+2=4

2. Write short notes on: 3x2=6

a) Meninges

b) Corpus callosum

c) Lingual nerve

3. Describe production and circulation of CSF. 6

Group “B” (Physiology)

4. Define a synapse. Enumerate the steps in synaptic transmission. 3+1=4

5. Illustrate the pathway of pain sensation from the periphery to the brain. 6

6. Write short notes on: 3x2=6

a) Basis of stretch reflex

b) Facial paralysis

Group “C” (Biochemistry)

7. Sketch the explanatory diagram of thick and thin filament interaction &regulation by

level of calcium. 5

8. Define: 3

47

a) Hyperpolarizaton

b) Action potential

c) Depolarization

Group “D” (Microbiology)

9. List enzymes and toxins produced by staphylococci. 4

10. Define meningitis. List any three common organisms causing bacterial meningitis. 4

Group “E” (Pathology)

11. Define osteoporosis. List two causes of generalized osteoporosis. 2+2=4

12. Define neoplasia. List two malignant tumor of skin. 2+2=4

13. Describe the gross and microscopic features of osteogenic sarcoma. 4

14. Define hydrocephalus and list its important complications. 2+2=4

Group “F” (Pharmacology)

15. Name six drugs of NSAIDs category and state the uses and side effects of aspirin.

2+2+2=6

16. State why preanaesthetic drugs are used in general anaesthesia. Name three

preanaesthetic drugs and their actions. 2+2+2=6

17. Write short note on pentazocaine. 2

18. Name two drugs of intermediate local anesthesia and state why adrenaline is used in

local anesthesia. 2

**********************************************

2063/8

Group “A” (Anatomy)

1. Parts of corpus callosum. 2

2. Trace the pathways of pain and temperature. 2

3. Origin, termination and area of supply of lingual nerve. 2

4. Origin, insertion and nerve supply of deltoid muscle. 2

5. Colle’s fracture 2

6. Erbs palsy 2

7. Attachments, nerve supply and action of masseter muscle. 2

8. Derivatives of neural crest cells. 2

48

Group “B” (Physiology)

9. How is nerve impulse conducted in myelinated and non-myelinated neurons? What

factors influence the velocity of conduction? 2+2=4

10. Name four properties of skeletal muscle. How does skeletal contraction differ from

smooth muscle contraction? 2+2=4

11. Write short notes on any FOUR: 2x4=8

a. Any four functions of the hypothalamus

b. Facial paralysis (lower motor neuron types)

c. Conduction deafness

d. Myopia

e. Sensations carried by posterior columns

Group “C” (Pathology)

12. Briefly describe the microscopic features of malignant melanoma of skin. 4

13. Briefly describe the stages of fracture healing. 4

14. Describe the pathological findings of CSF and brain in bacterial meningitis. 4

15. Mention the morphology of Ewing sarcoma 4

Group “D” (Pharmacology)

16. List neuromuscular blocking agents. Describe the mechanism of action and adverse

effects of pancuronium. 3+1+2=6

17. List anti-histamines. Give their indications and adverse effects. 2+2+2=6

18. How NSAIDs work? List their adverse effects. 3+1=4

Group “E” (Biochemistry)

19. Explain the role of parathyroid and calcitriol in calcium metabolism and describe the

function of Na-K ATP plate. 4

20. Explain the mode of opening and closing of ion channels in plasma membrane and

propagation of nerve impulse. 2+2=4

Group “F” (Microbiology)

21. List any THREE organisms those causing meningitis. 4

22. Write short notes on op- coagulase test. 4

**********************************************

49

2062/07

Group “A” (Anatomy)

1. Describe the production and circulation of C.S.F. 4

2. How can the three types of muscle tissue be distinguished on the basis of location,

microscopic appearance and nervous control? 4

3. Write short notes on: 3+3=6

a. Meninges

b. Fascia

Group “B” (Physiology)

4. List the steps in neuromuscular transmission. What is the defect in myasthenia

gravis? 3+1=4

5. Illustrate the pathway for pain sensation from the periphery to the brain. Which type

of nerve fibers is most susceptible to local anesthetics?

3+1=4

6. What features are seen in upper motor neuron disorder? What is Babinski sign?

3+1=4

7. Explain the basis of stretch reflex. List any four properties of a reflex. 2+2=4

Group “C” (Pathology)

8. Describe the morphological features of tuberculous osteomyelitis. 4

9. Describe the laboratory findings of acute pyogenic meningitis. 4

10. Write short notes on any two: 2x4=8

a) Meningioma

b) Vocal cord polyp

c) Berry aneurysm

Group “D” (Pharmacology)

11. List NSAIDs. Mention the advantages and disadvantages of selective COX2 inhibitors.

4+2+2=8

12. Write short notes on:

a) Mechanism of action and adverse effects of lignocaine 5

b) Use of phenytoin 3

Group “E” (Biochemistry)

13. Define neurotransmitter. Explain inhibitory function o snake venom. 3

50

14. List biological role of calcium. Describe physiological functions and control of PTH. 5

Group “F” (Microbiology)

15. Describe morphology of Neisseria meningitidis in CSF. 3

16. Sketch a neat diagram of herpes virus and label it properly. 5

**********************************************

2061/7

Group “A” (Anatomy)

1. Explain the trigeminal nerve on the following: 2+2+2=6

a) Its different nuclei and location

b) The foramina through which its three divisions exit out of the cranial cavity.

c) The muscles innervated by it.

2. Define a joint. List the factors which are important for the stability of a joint.

1+3=4

3. Write short notes on: 2+2+2=6

a) Corticospinal tract

b) Different parts of basal ganglia and their parts

c) Dislocation of TMJ

Group “B” (Physiology)

4. Mention the functions of calcium. 4

5. How do you perform the “Trigeminal nerve” test clinically? 4

6. List the steps in neuro-muscular transmission. What is myasthenia gravis?

3+1=4

7. Explain briefly how pain is transmitted from the periphery to the cerebral cortex. 4

Group “C” (Pathology)

8. Describe etiology and pathological features of cerebrovascular accidents. 8

9. Write short notes on: 2x4=8

a) Pilocytic astrocytoma

b) Gout

Group “D” (Pharmacology)

10. Describe the mechanism of action of NSAIDs. Give the important adverse effects of

NSAIDs. 3+2=5

51

11. Define local anesthesia. Explain the mechanism of action and adverse effects of

lignocaine. 2+3+2=7

12. Describe the mechanism of action of the following drugs: 2x2=4

a) Paracetamol

b) Alprazolam

Group “E” (Biochemistry)

13. Explain the role of Vit. D in calcium homeostasis in our body. 3

14. Outline the synthesis of acetylcholine and its degradation in myoneural function.

3

15. List the energy sources (fuels) for proper skeletal muscle function. 2

Group “F” (Microbiology)

16. Mention briefly about any three most common bacteria causing meningitis. 3

17. Write short notes on Herpes virus. 5

**********************************************

2061/1

Group “A” (Anatomy)

1. Describe the extracranial course and branches of facial nerve (VII). What will happen

if it is cut at the level of stylomastoid foramen? 4+2=6

2. Describe the Temporomandibular joint under the following headings:

a) Movements 2

b) Nerve supply 2

c) Articular disc

3. Write note on: 2x2=4

a) Deltoid muscle

b) Cerebellum

Group “B” (Physiology)

4. Define the followings: 2x2=4

a) Motor unit

b) Chemical synapse

5. Write short notes on any THREE: 3x4=12

a) Acetylcholine receptor

52

b) Fast and slow pain

c) Factors regulating bone mineralization

d) Contraction of muscle

Group “C” (Pathology)

6. Write down findings of cerebrospinal fluid in pyogenic and tuberculous meningitis.

2+2=4

7. Describe the healing process of bone fracture. 4

8. Describe the gross & microscopic features of malignant melanoma of skin. 4

9. Describe briefly the etiopathogenesis of rheumatoid arthritis. 4

Group “D” (Pharmacology)

10. List the local anesthetic drugs. Highlight its uses in dental clinic practice. 5+5=10

11. Name antifungal drugs. 6

OR

Name NSAID drugs

Group “E” (Biochemistry)

12. Define: 4x1=4

a) Synapse

b) Synaptic vesicle

c) Neurotransmitter

d) Depolarization

13. Describe the role hormones in calcium in calcium homeostasis. 4

Group “F” (Microbiology)

14. List the causative agents of bacterial meningitis. Describe the laboratory diagnosis of

meningitis. 1+3=4

15. Write short notes on: 2x2=4

a. Staphylococcus aureus

b. Herpes Virus

**********************************************

2060

Group “A” (Anatomy)

1. Enumerate the muscles of facial expression. Describe the buccinator muscle.

2+2=4

53

2. Write short notes on the following: 3x2=6

a. Arterial circle at the base of the brain

b. Corpus callosum

c. Lingual nerve

3. Write short notes on the following: 3x2=6

a. Blood supply of a long bone

b. Adductor muscles of shoulder joint

c. Sternocleidomastoid

Group “B” (Physiology)

4. Define a synapse. Enumerate the steps in synaptic transmission. 1+3=4

5. Mention the effects of sympathetic and parasympathetic stimulation on the heart,

gastrointestinal tract and urinary bladder. 2+2+2=6

6. Write short notes on: 2x3=6

a) Color blindness

b) Facial paralysis

Group “C” (Pathology)

7. Define osteoporosis. List two causes of generalized osteoporosis. 2+2=4

8. Define neoplasia. List two malignant tumors of skin. 2+2=4

9. Describe the gross and microscopic features of osteogenic sarcoma. 4

10. Define hydrocephalous and list its important complications. 2+2=4

Group “D” (Pharmacology)

11. Name 6 drugs of NSAIDs category and state the uses and side effects of aspirin.

2+2+2=6

12. State why preanaesthetic drugs are used in general anesthesia. Name three

preanaesthetic drugs and their actions. 2+2+2=6

13. Write short note on pentazocaine. 2

14. Mane two drugs of intermediate local anesthesia and state why adrenaline is used in

local anesthesia. 2

Group “F” (Microbiology)

15. List enzymes and toxins produced by staphylococci. 4

16. Write note on Herpes simplex virus. 4

**********************************************

54

2059

Group “A” (Anatomy)

1. Describe the fifth cranial nerve on the following headings: 6

a. Position of its nuclei

b. Its divisions and muscles supplied by it.

2. Mention nerves with their functional components supplying the tongue. 5

3. List the muscles of rotator cuff and their nerve supply. 5

Group “B” (Physiology)

4. Mention the different types of muscles. Give their special characteristic. Describe the

function of each varieties. 3+2+3=8

5. Enumerate the various centers in the cerebral cortex. Mention the functions of

cerebral cortex. 3+5=8

Group “C” (Pathology)

6. Classify different types of leprosy. 4

7. Describe the microscopic features of glioblastomamultiforme. 4

8. List the tumors of bone. 4

9. Describe the findings of cerebrospinal fluid in tuberculous meningitis. 4

Group “D” (Pharmacology)

10. Write down the mechanism of action of suxamethonium. (succinylcholine) 4

11. Classify local anesthetics and state the properties of lidocaine. 4

12. Describe the mechanism of action of morphine. 4

13. Give the important: 2x2=4

a) Uses of diazepam

b) Adverse effects of aspirin

Group “E” (Biochemistry)

14. Give two examples of excitatory neurotransmitter derived from amino acids as well

as two examples of inhibitory derived from peptide. 2+2=4

15. Describe how calcitonin calcium level in blood. 4

Group “F” (Microbiology)

16. List the causative microorganisms of community acquired meningitis according to the

age of the patient. 4

55

17. Briefly describe the morphology, pathogenesis and laboratory diagnosis of

poliomyelitis virus. 4

**********************************************

2058

Group “A” (Anatomy)

1. List different parts of brainstem. List the nuclei present in midbrain. 2+4=6

2. Mention the location of facial nerve nucleus. List its functional components.

6

3. List the muscles of mastication and their actions. 2+2=4

Group “B” (Physiology)

4. Define light reflex. Trace the path of light reflex with a diagram. 2+3=5

5. Name the muscle proteins. Mention the changes occurring during muscle

contraction. 2+3=5

6. Write notes on: 3x2=6

a) Periosteum

b) Cerebellum

c) Basal ganglia

Group “C” (Pathology)

7. Describe the microscopic features of psoriasis. 5

8. Classify the tumors of bone with examples. 6

9. Describe the etiopathogenesis of acute meningitis. 5

Group “D” (Pharmacology)

10. List benzodiazepams what is their mechanism of action? 4

11. List the different NSAIDs. What is their mechanism of action? List their indications.

2+4+2=8

12. What are the drugs used for preanaesthetic medication and what is the rationale for

their use? 4

Group “E” (Biochemistry)

13. List the steps in skeletal muscle contraction (give your answer with diagram). 4

14. Explain briefly hormonal control of serum calcium level. 4

56

Group “F” (Microbiology)

15. List the causative agents of bacterial and viral meningitis. 2

16. Briefly mention the laboratory diagnosis of meningococcal meningitis. 2

17. Briefly describe the pathogenesis of herpes simplex type 1 and laboratory diagnosis.

2+2=4

**********************************************

2058

Group “A” (Anatomy)

1. Give a short account on the development of cerebellum. 4

2. Write short notes on: 4x3=12

a) Inferior alveolar nerve

b) Lateral plate mesoderm

c) Medial pterygiod muscle

d) Sphenomandibular ligament

Group “B” (Physiology)

3. What are the receptors of pain? What is the pathway for the sensation of the pain? 4

4. What is acetylcholine? Where is it secreted? What is myasthenia gravis? 4

5. What is coordination between the functions of basal ganglia and the cerebellum? 4

6. What are the functions of hypothalamus? 4

Group “C” (Pathology)

7. Describe the etiopathogenesis of acute meningitis. 4

8. Describe the complication of cerebrovascular accidents. 4

9. Describe the pathological features of meningioma. 4

10. Describe the etiology of acute osteomyelitis. 4

Group “D” (Pharmacology)

11. Classify general anesthesia and state the properties of halothane. 4

12. State 6 drugs of six different types of NSAIDs and state the uses and properties of

NSAIDs. 4

13. Compare the properties of pethidine with morphine. 2

14. Mention 2 drugs each of intermediate and long acting anesthetics and why

adrenaline is used in local anesthetics. 2

15. Name a preanaesthetic drug that produces anti-emetic effect. 1

57

16. Name a drug of NSAID that inhibits platelet aggregation and has a long half life and

produce less ulcer. 1

17. Mention a transmitter on which diazepam produces its action. 1

18. Name a drug which produces muscle relaxation by centrally acting. 1

Group “E” (Biochemistry)

19. What is the function of acetylcholine and role of acetylcholinesterase. 4

20. What are the hormones involved in calcium homeostasis? What is activation of Vit.

D? 4

Group “F” (Microbiology)

21. Identify the causative agents of poliomyelitis. 4

22. Describe oncogenic viruses. 4

**********************************************

2057

Group “A” (Anatomy)

1. Describe the formation of temporomandibular joint? List the possible movements at

these joints, muscles producing the movements and their nerve supply. 6

2. Name the different parts of the brainstem? Describe in brief the nucleus, course and

branches of facial nerve. 6

3. Write brief notes on:

a. Neurulation 2

b. Microscopic anatomy of bone 2

Group “B” (Physiology)

4. Define catecholamine. Compare and contrast between different catecholamine.

4+2=6

5. Describe lower motor neuron paralysis. 4

6. Compare between the functions of two parts of pituitary gland- adenohypophysis

and neurohypophysis. 4+2=6

Group “C” (Pathology)

7. Describe the etiopathogenesis of acute osteomyelitis. 4

8. Describe the microscopic features of squamous cell carcinoma. 4

9. Classify the tumors of the brain. 4

58

10. Describe the microscopic features of lichen planus. 4

Group “D” (Pharmacology)

11. Classify the local anesthetics and mention the techniques used (method for local

anesthetic). 4

12. Mention the alkaloids present in opium. State the properties and toxic effects of

morphine. 4

13. Classify the muscle relaxant drugs and mention the effects of D-tubocuranine in

autonomic ganglia and mast cell. 4

14. States why premedication is necessary and mention the different premedication

drugs in anesthesia and their effects. 4

Group “E” (Biochemistry)

15. Give simple diagrammatic explanation of skeletal muscle contraction regulation by

calcium. 3+1=4

16. List four important points of difference between cardiac and skeletal muscle in

relation to their contraction. 2

17. Define: 2

a. Action potential

b. Hyperpolarization

Group “F” (Microbiology)

18. List the types of Herpes viruses. Describe Herpes simplex type 1 and laboratory

diagnosis. 4

19. List the three important agents of bacterial meningitis. Describe the morphological

and cultural characters of meningococci. 4

**********************************************

59

Dental Material

Science

60

2071/7

Candidates are required to give their answers in their own words as far as practicable.

The figures in the margin indicate full marks.

Attempt all the questions.

1. List the material of choice in restoration of class I cavity. Compare the physical

and mechanical properties of dental amalgam and composite. And write its

advantage, disadvantage & uses. 2+6+4=12

2. Describe various polymerization technique of composite resin. Mention their

advantage & disadvantage. What is polymerization shrinkage? 4+5+3=12

3. Define stress and strain. What are the type of stress? Draw stress-strain curve.

2+4+6=12

4. Classify dental wax along with their uses. Describe composition, type and

properties of inlay wax. 5+3+4=12

5. Write steps of casting procedure. What are the casting defect and their causes.

Write detail about porosity. 4+5+3=12

6. Write short notes on:- 5x4=20

a) 18-8 stainless steel wire

b) Soldering and welding

c) Causes of marginal deterioration of dental amalgam restoration

d) Classify direct filling gold

***************************

2071/2

1. Classify dental cements. Write down the advantages, disadvantages and uses of Glass

Ionomer Cements (GIC). Add a note on Resin modified GIC. 4+6+2=12

2. Define composite resin. Classify composite resin on the basis of particle size and mode

of curing. Write down the advantage and disadvantage of light cure composites.

2+4+6=12

3. What are the various elastomeric impression materials? Write composition, setting

reaction and uses of any one of them. 2+5+5=12

4. Define the terms: study models, cast & die. Describe the composition and uses of inlay

wax. Discuss different type of investment materials with their uses. 3+4+5=12

Bachelor Level/BDS (FIRST Year)/ IOM Time: 3 hours

Dental Material Science IV Full Marks: 80

61

5. Define stress and strain. What are the types of stress? Draw stress-strain curve.

2+4+6=12

6. Write short notes on:- 5x4=20

e) Calcium Hydroxide

f) Dental abrasives

g) Flux

h) Hue, value and chroma

**************************

2070/8

1. Classsify dental waxes along with their uses. Describe composition, type and

properties of inlay wax. 5+3+4=12

2. Write different types of casting investment materials, their composition and

properties. 4+4+4=12

3. Define impression. Classify impression materials according to use in dentistry.

3+9=12

4. Classify dental amalgam. What are the factors affecting strength of dental amalgam.

Add a note on effect of moisture contamination in dental amalgam. 4+6+2=12

5. Define tarnish and corrosion. Classify corrosion. Explain in detail about galvanic

corrosion. Briefly explain how to protect against corrosion.

2+2+5+3=12

6. Write short notes on: 5x4=20

a) Mercury toxicity

b) Dentrifrices

c) Eutectic alloys

d) Dental implant materials

**********************************************

2069/9

1. Define gypsum. Classify gypsum products. Elaborate different dental plasters.

2+2+8=12

2. Describe casting shrinkage. Describe the importance of expansion of investment

materials. 5+7=12

3. Classify composite resin. Write in detail about restorative procedures of Class I cavity

with composite resin. Write a note on siloranes. 4+7+1=12

62

4. What are high copper amalgam alloys? What are their advantages? Describe their

setting reaction. 2+4+6=12

5. Classify dental porcelain. Discuss the composition and properties of dental

porcelain. Write a note on porcelain teeth. 2+3+3+4=12

6. Write short notes on: 5x4=20

a) Separating Medium

b) Classification of dental waxes

c) Creep & Flow

d) Sandwich Technique

**********************************************

2068/8

1. Define composite resin. Give its composition. Explain the advantages and

disadvantages of light cure composite resin. 2+5+5=12

2. Define gypsum. Classify gypsum products. Elaborate different dental plasters.

2+2+8=12

3. Classify glass ionomer cement. Explain the biological properties of glass ionomer

cement. Explain in detail about miracle mix. 2+4+6=12

4. Name the various elastomeric impression materials. Give the composition, setting

reaction and uses of any two of them. 2+5+5=12

5. Describe in detail about soldering, welding and brazing. 4+4+4=12

6. Write short notes on: 5x4=20

a) 18-8 stainless steel

b) Biomaterials of dental implant

c) Glazing of porcelain

d) Anticariogenic properties of a restorative material.

*********************************************

2068/3

1. Name the various elastomeric materials. Give the composition, setting reaction and

uses of any one of them. 10

2. Describe the composition of composite resin. Write about the various curing

mechanisms of composite resin. 10

3. What are the causes of defective casting? Write in detail about porosity. 10

4. Describe the terms soldering, welding and brazing. 10

5. Write short notes on: 5x8=40

63

a) Coefficient of thermal expansion

b) Gelation process of alginate

c) Elastic limit and proportional limit

d) Flux

e) Properties of dental ceramic

f) Biomaterials for dental implant

g) Hazards of mercury

h) Glazing of porcelain.

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2067/4

1. List the desirable properties of an investment material and write about the expansion

with investment. 10

2. List the various elastomeric impression materials. Give the composition, setting

reaction and uses of any one of them. 10

3. Write the composition of amalgam alloy. Describe the manipulation of amalgam and

objectives of each manipulation step. 10

4. What are the causes of casting failures? Write in detail about porosity. 10

5. Write short notes on: 5x8=40

a) Glazing of porcelain

b) Classification of dental waxes

c) Sprue former

d) Dentin bonding agent

e) Setting of composite resin

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2066/2

1. Write the definition, composition and classification of dental amalgam. How can we

improve the strength of amalgam restoration? 10

2. Classify investment materials. Describe the various setting expansions with

investment and its significance. 10

3. Classify dental casting alloys. Describe casting shrinkage. 10

4. Short notes: 4x5=20

a. Acid etch technique

b. Properties of Zinc phosphate cement

64

c. Retention of glass ionomer cement

d. Drawbacks of dental ceramics

5. Write in brief: 5x6=30

a. Significance of dimensional stability

b. Creep

c. Corrosion

d. Biological property of composite resin

e. Advantages of polishing surface of various restorative materials.

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2064/8

1. Write the composition of amalgam alloy. Describe the manipulation of amalgam and

objectives of each manipulation step. 10

2. Give the composition of dental ceramics. Enumerate its advantages and

disadvantages. 10

3. Classify impression materials. Describe addition silicon impression material. 10

4. Write short answer: 5x5=25

a) What is cold welding? What are the requirements for cold welding?

b) Write in brief the properties, advantages and disadvantages of zinc

phosphate cement.

c) Give the composition, purposes of using and precautions observed in case of

separating medium.

d) Explain about the failures in casting.

e) Discuss about monomer-polymer interaction.

5. Write short notes on: 5x5=25

a) Dental wax

b) Creep

c) Setting of composite resin

d) Dental implant materials

e) Setting of gypsum

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2063/8

1. Define gypsum and classify gypsum products. Elaborate any one. 10

2. Elaborate composites with their setting mechanism. 10

65

3. Define and discuss tarnish and corrosion with respect to dental materials.10

4. Name the various elastomeric impression materials. Give the composition, setting

reaction and uses of any one of them. 10

5. Write short notes on: 5x8=40

a) Incomplete casting

b) Dental implant materials

c) Dental waxes

d) Glazing of porcelain

e) Low strength bases

f) Separating medium

g) Hazards of mercury

h) Calcium hydroxide

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2062/12

1. Define and classify impression materials. Give the composition and uses of alginate.

Explain its advantages and disadvantages. 15

2. Classify denture base materials. Discuss the causes of porosities in acrylic denture

base. 15

3. Classify dental cements. Write the composition, uses and properties of zinc

phosphate cement. 15

4. Write short notes on: 7x5=35

a) Porosities in metal casting

b) Advantage and disadvantages of amalgam

c) Dental porcelain

d) 18-8 stainless steel wire

e) Soldering and welding

f) Dental implant materials

g) Gypsum products

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2062/7

1. Describe the terms soldering, welding and brazing. 10

2. Describe the composition, setting mechanism and properties of alginate. 10

3. Give the composition of composite resin. Describe the various polymerization

systems for composite resins. 10

66

4. Define gypsum. Elaborate various dental plasters. 10

5. Write short notes on: 8x5=40

a) Impression materials

b) Dental waxes

c) Casting failures

d) Functions of acid etching

e) Orthodontic wire

f) Properties of dental ceramic

g) Zinc oxide eugenol paste

h) Biomaterials for dental implant.

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2061/7

1. Mention the composition of composite resins. Discuss the polymerization mechanism

of composite resins. 10

2. Discuss the setting expansion of investment material to compensate for casting

shrinkage. 10

3. Write short notes on: 6x5=30

a) Elastic limit and proportional limit

b) Sprue former

c) Casting ring liners

d) Anticariogenic property of silicate cement

e) Properties of zinc phosphate cement

4. Write in brief: 6x5=30

a) Effect of mercury content on properties of amalgam restoration

b) Flux

c) Dental stone

d) Composition and setting reaction of zinc oxide eugenol

e) Impression paste

f) Localized shrinkage porosity

g) Condensation of porcelain for fabrication of metal ceramic restoration

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67

2061/1

1. Answer any TWO: 2x10=20

a. Describe the factors affecting the strength of amalgam restoration.

b. Classify the impression materials with the composition, setting reaction,

advantages and disadvantages of alginate impression material

c. Describe the different types of gypsum products. Describe the setting of

gypsum and factors affecting the setting time.

2. Write in brief: 6x5=30

a. Level I test for toxicity evaluation of dental material

b. Biological properties of glass ionomer cement

c. Phosphate bonded investments

d. Composition of composite resin

e. Sprue former

f. Tarnish and corrosion

3. Write short notes on (any SIX): 6x5=30

a) 18-8 stainless steel

b) Creep and flow

c) Localized shrinkage porosity

d) Gold foil

e) Classification of dental casting alloys]

f) Uses of varnish

g) Composition of porcelain

h) Addition polymerization of synthetic resin

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2060

1. Describe the composition of composite resin. Write about the various curing

mechanisms of composite resin. 10

2. Describe different types of gypsum products. Write about the setting expansion of

gypsum. 10

3. What are the causes of defective casting? Write in detail about porosity. 10

4. Describe in brief: 5x5=25

a. Gelation process of alginate

b. Copolymerization

c. Dentin bonding agent

d. Zinc phosphate cement

68

e. Coefficient of thermal expansion

5. Write short notes on: 5x5=25

a. Glazing of porcelain

b. Definition of soldering, brazing and welding

c. Sprue former

d. Thermal conductivity and thermal diffusivity

e. Condensation of dental amalgam

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2059

ATTEMPT ANY FIVE QUESTIONS

1. List various elastomeric impression materials. Describe the composition, setting

reaction and properties of condensation silicone. 16

2. What is corrosion? Discuss different types of corrosion. 16

3. Classify denture base materials. Discuss the causes of porosity in acrylic denture

base. 16

4. Write the composition of porcelain. Describe the importance and methods of its

condensation. 16

5. Write short notes on: 4x4=16

a. Composition and uses of varnish

b. Modulus of elasticity

c. Mechanism of gelation

d. Tarnish and corrosion

6. Write short notes on: 4x4=16

a. Porosity in metal casting

b. 18-8 stainless steel

c. Setting gypsum

d. Composition of composite resin

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2058

1. Classify dental cements. Write in detail about zinc oxide eugenol cement. 10

2. Name different types of waxes used in dentistry. Describe the composition and

properties of inlay wax. 10

3. Describe different types of gypsum products. Describe the factors affecting the

setting time of gypsum. 10

69

4. Classify composite resin. Write in detail about the small particle composite resin. 10

5. Write short notes on: 4x5=20

a. Fluxes

b. Dental varnish

c. Stone plaster

d. Incomplete casting

6. Describe in brief:

a. Anticariogenic property of glass ionomer cement

b. Composition of porcelain

c. Degassing of direct filling gold

d. Precautions to be taken during investment of cast restoration.

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2058

ATTEMPT ANY FIVE QUESTIONS

1. Define tarnish and corrosion. Classify corrosion and write in short about galvanic

corrosion. 16

2. Write the composition and properties of glass ionomer cements. Describe its

adhesive and anticariogenic properties. 16

3. Define welding and soldering. What are the requisites of good dental solder and

function using dental flux. 16

4. Describe the different types of gypsum used in dentistry. Write the setting of

gypsum. Enumerate the factors affecting the strength of plaster. 16

5. Write short notes on: 4x4=16

a. Stress and strain

b. Stages of polymerization

c. Annealing

d. Classification of impression material

6. Compare the following: 6+5+5=16

a. High copper and low copper amalgam

b. Normal and hygroscopic expansion

c. Dual cure and tri-cure system

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70

2057

1. List the luting cements. Write in detail about the polycarboxylate cement.16

2. Classify the casting defects. Describe the causes of surface roughness and

irregularities. 16

3. What is dental amalgam? Write its composition and factors affecting the strength of

amalgam investment. 16

4. Give differences between followings: 4x4=16

a) Malleability and ductility

b) Rigidity and flexibility

c) Resilience and toughness

d) Creep and flow

5. Write short notes on: 4x4=16

a) Acid etching

b) Advantages and disadvantages of glass ionomer

c) Composition and setting of alginate

d) Composition and desirable properties of inlay wax.