APPENDIX - mhlw...APPENDIX A 1-4 CLINICAL OBSERVATION : SUMMARY, MOSUE: FEMALE (2Week STUDY)...

酢酸ビニルのラット及びマウスを用いた

経口投与によるがん原性予備試験(混水試験)報告書

APPENDIX

(A1－1～A10－４)2 週間試験：ラット/0134；マウス/0135

APPENDIX A 1-1

CLINICAL OBSERVATION : SUMMARY, RAT : MALE

(2Week　STUDY)

APPENDIX A 1-2

CLINICAL OBSERVATION : SUMMARY, RAT : FEMALE

(2Week STUDY)

APPENDIX A　1-3

CLINICAL OBSERVATION : SUMMARY, MOSUE : MALE

(2Week STUDY)

APPENDIX A 1-4

CLINICAL OBSERVATION : SUMMARY, MOSUE: FEMALE

(2Week STUDY)

APPENDIX A 2-1

BODY WEIGHT CHANGES :SUMMARY, RAT : MALE

(2Week STUDY)

APPENDIX A 2-2

BODY WEIGHT CHANGES : SUMMARY, RAT : FEMALE

(2Week STUDY)

APPENDIX A 2-3

BODY WEIGHT CHANGES :SUMMARY, MOSUE : MALE

(2Week STUDY)

APPENDIX A 2-4

BODY WEIGHT CHANGES : SUMMARY, MOSUE: FEMALE

(2Week STUDY)

APPENDIX A 3-１

WATER CONSUMPTION CHANGES : SUMMARY, RAT: MALE

(2Week STUDY)

APPENDIX A 3-2

WATER CONSUMPTION CHANGES : SUMMARY, RAT: FEMALE

(2Week STUDY)

APPENDIX A 3-3

WATER CONSUMPTION CHANGES : SUMMARY, MOUSE: MALE

(2Week STUDY)

APPENDIX 3-4

WATER CONSUMPTION CHANGES : SUMMARY, MOUSE: MALE

(2Week STUDY)

APPENDIX A 4-1

FOOD CONSUMPTION CHANGES : SUMMARY, RAT : MALE

(2Week STUDY)

APPENDIX A 4-2

FOOD CONSUMPTION CHANGES : SUMMARY, RAT : FEMALE

(2Week STUDY)

APPENDIX A 4-3

FOOD CONSUMPTION CHANGES : SUMMARY, MOSUE : MALE

(2Week STUDY)

APPENDIX A 4-4

FOOD CONSUMPTION CHANGES : SUMMARY, MOSUE : FEMALE

(2Week STUDY)

APPENDIX A 5-1

CHEMICAL INTAKE CHANGES: SUMMARY, RAT : MALE

(2Week STUDY)

APPENDIX A 5-2

CHEMICAL INTAKE CHANGES: SUMMARY, RAT : FEMALE

(2Week STUDY)

APPENDIX A 5-3

CHEMICAL INTAKE CHANGES: SUMMARY, MOUSE: MALE

(2Week STUDY)

APPENDIX A 5-4

CHEMICAL INTAKE CHANGES: SUMMARY, MOUSE: FEMALE

(2Week STUDY)

APPENDIX A 6-1

HEMATOLOGY : SUMMARY, RAT : MALE

(2Week STUDY)

APPENDIX A 6-2

HEMATOLOGY : SUMMARY, RAT : FEMALE

(2Week STUDY)

APPENDIX A 6-3

HEMATOLOGY : SUMMARY, MOSUE : MALE

(2Week STUDY)

APPENDIX A 6-4

HEMATOLOGY : SUMMARY, MOSUE : FEMALE

(2Week STUDY)

APPENDIX A 7-1

BIOCHEMISTRY : SUMMARY, RAT : MALE

(2Week STUDY)

APPENDIX A 7-2

BIOCHEMISTRY : SUMMARY, RAT : FEMALE

(2Week STUDY)

APPENDIX A 7-3

BIOCHEMISTRY : SUMMARY, MOSUE : MALE

(2Week STUDY)

APPENDIX A 7-4

BIOCHEMISTRY : SUMMARY, MOSUE : FEMALE

(2Week STUDY)

APPENDIX A 8-1

GROSS FINDINGS : SUMMARY, RAT : MALE :SACRIFICED ANIMALS

(2Week STUDY)

APPENDIX A 8-2

GROSS FINDINGS : SUMMARY, RAT : FEMALE : SACRIFICED ANIMALS

(2Week STUDY)

APPENDIX A 8-3

GROSS FINDINGS : SUMMARY, MOUSE : MALE : SACRIFICED ANIMALS

(2Week STUDY)

APPENDIX A 8-4

GROSS FINDINGS : SUMMARY, MOUSE : FEMALE : SACRIFICED ANIMALS

(2Week STUDY)

APPENDIX A 9-1

HISTOLOGICAL FINDINGS : NON-NEOPLASTIC LESIONS : SUMMARY

RAT : MALE : SACRIFICED ANIMALS

(2Week STUDY)

APPENDIX A 9-2

RAT : FEMALE : SACRIFICED ANIMALS

(2Week STUDY)

APPENDIX A 9-3

MOUSE: MALE : SACRIFICED ANIMALS

(2Week STUDY)

APPENDIX A 9-4

MOUSE : FEMALE : SACRIFICED ANIMALS

(2Week STUDY)

APPENDIX A 10-1

IDENTITY OF VINYL ACID

(2Week STUDY)

APPENDIX A 10-2

STABILITY OF VINYL ACID

(2Week STUDY)

APPENDIX A 10-3

CONCENTRATION OF VINYL ACETAIE IN DRINKING WATER

(2Week STUDY)

APPENDIX A 10-4

STABILITY OF VINYL ACETATE IN DRINKING WATER

(2Week STUDY)

APPENDIX - mhlw...APPENDIX A 1-4 CLINICAL OBSERVATION : SUMMARY, MOSUE: FEMALE (2Week STUDY)...

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