Phenytoin

11 Phenytoin 50 mg / tab, 100 mg / cap 50 mg / ml in 5 ml. injection (grand mal) complex partial (psychomotor temporal lobe) ()

Status epilepticus ;loading dose;15-20 mg/kg

maintenance dose 5mg/kg/day 2 usual dose; 6 - 3 8-10 mg/kg/day 4-6 7.5-9mg/kg/day 7-9 7-8 mg/kg/day 10-16 6-7 mg/kg/day ( 8 )

; loading dose15-20 mg/kg/day 100-150 mg 30 1500 mg/24 hours

maintenance dose ; 300mg/day 5-6 mg/kg/day 3 extended release 2

50 ./

Anticonvulsant loading dose 15-20 mg/kg 3 2-4

maintenance dose Heart block, Sinus bradycardia IV

> 20 mcg/ml >30 mcg/ml >40 mcg/ml mental capacity

antidote Pregnancy Risk Factor D ()

12

(Drug Interactions) 1. Rifampicin, folic acid, theophylline, NG feeding Phenytoin 2. Amiodarone, chloramphenicol, cimetidine, fluconazole, isoniazid, metronidaole, nifedipine,

norfloxacin, omeprazole, phenobarbital, ticlopidine Phenytoin

: 1. ( ) 2.

1. 2. 2. 3.

4. Phenytoin

5. 6. 7.

8.