ифар 15.04.13 сколково

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  • 1. 2013 Copyright iPhaR ,
  • 2. - , : ( 60 3 )2013 Copyright iPhaR
  • 3. : IP Start-up 2013 Copyright iPhaR
  • 4. ( ,, IP)(, ) ( )( )R&D- ( 60,4 12 2013 Copyright iPhaR
  • 5. :, (), (), () .:, (), (), (): , ,, . 2013 Copyright iPhaR
  • 6. . .. ( ) , . 100 . . -, 8 , 10 .. .. ( ) - .Prof. Gogvadze V. ( , ) - .Dr. Schwarz J. (Nano Essentials Inc., ) - TEVA ().Dr. Cleverley S. (ISIS Innovation, ) . . ..2013 Copyright iPhaR
  • 7. 2013 2014 2015 20161. 2. , 3. 4. - - 2013 - 2015 4 :2013 Copyright iPhar
  • 8. : (H+/K+-A )IP: RU 2465274, 05.03.2010; PCT/RU2011/000103; ( ); (11750980.2 04.10.2012); AO. ( ): ; ; - ; . 1) ; 2) .. 2013 Copyright iPhar
  • 9. - N-[3-(4-nitrophenylamino)-indole-2-ilmethylene]aminoguanidine hydrochloride NO-.IP: RU 2478618, 15.03.2010; PCT/RU 2011/000142; (13/634,840 13.09.2012), (11756610.9 12.10.2012), EAO. () - , , NO-. - (ED50 50 /, , ) (50>5000 /, ).. - $10 . 2013 Copyright iPhar
  • 10. (), .IP: RU 2418577, 24.12. 2009; PCT/RU2010/000778; (No.13/518,814 22.06.2012), (10844832.5 20.07.2012), . : , ; , ( MAO OMT ); (, ) ; . :1) ; 2) ; 3) . 2013 Copyright iPhar
  • 11. - -3 - .IP: RU ( 08.11.2011); PCT/RU2012/000884. : , . , , .. , , . in in vitro( ) in vivo ( , , ). :10 -7 (in vitro), 4-12 / (per os), 0,01-1,0 mg/kg (intravenously). - 50 - 8900 / (, per os) .. $15 ./. .2013 Copyright iPhar
  • 12. , - Bardoxolone methyl(Reata Pharmaceuticals/ Abbott Laboratories), III antioxidant inflammation modulator II . Nrf2k,NFkB PPAR. :1) ;2) ( ,, ).IP: RU 2401273, 30.03.2009; RU ( 2012129738 13.07.2012).: in vitro ( 0,5 5x10-6 ) in vivo/ - 50 > 5000 / (, per os). 2013 Copyright iPhar
  • 13. : ,, ... : 634021, , . , . 79/4./: +7 (3822) 248721: +7 (913) 8295599e-mail: gen_dir@iphar.ruwww.iphar.ru2013 Copyright iPhaR