1967

1973

1974

6~1177%

(1.35~1.5:1)

1%~3%

EB

(superantigensAg)()T

(heat shock proteinHSP)HSPHSP65KDHSP65HSP65Pt(P1)

MMPs MMPs

KD

1~9 10~21 22~60

594~100%353840

>1.5 cm

10

ALT

Clinical symptoms and signs of Kawasaki disease

PRQTQ QRS ST-T

WBCPLTESRCRPALB2-G

5d 54KD

1)63(8)

2)64()()

KDKDKDKDKDKD

BCGC-()BNPKD

KD

()

KobayashiIVIG133 mmolL(2) AST100 IUL(2) IVIG

: CT

(): 3

8mm3

IVIG 2g/kg/day11g/kg/day2 107 5

Aspirin 30~50mg/kg/day3233~5mg/kg/day168

IVIGKD

3~5mg/kg/day3 ESRCRPWBC

IVIG36 h(>38)27 dIVIG

IVGG A

Aspirin+Aspirin+

6

IVIG

2123611CTMRA

201.8%91%1~11 C11~21 21~60 107 5IVIG 1014IVIG14

80~100mg/kg/day4INR IVIG 36>38 27KD10

1 2030 mg/kg 1-3 2 mg/kg/d 22 2 mg/kg/d 3 1 2 mg/kg/d 46H2RNA 5000U/kg/ 3 13aRNAIIb/IIIaaKD3AHA()IVIG5