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2nd key player for health = Anti-free radical defences, the HSP
Free radicals
2nd link: cellular protection
The neutralisers: enzymes and their cofactors:S.O.D: Cu, Zn, Mn
G.P.X: Se
Catalase: Fe
Free radical scavngers
Vitamins A, C, E, β-carotene, flavonoides, (diet), etc.
Anti-free radical defenceFree radicals
Cellular aggression and protection:
UV rays, Inflammation, Infection Alteration of structural or physiological proteins (enzymes, hormones, etc.)
2nd key factor for health = Anti-free radical defence system, HSPs
2nd link: cellular protection
Repairing or evacuating proteins(Chaperon)
UV rays, Thermic shock, Inflammation, Infection
Changes in structural or physiological proteins (enzymes, hormones, etc.)
Stress proteins (HSP)
It is also…
Anti-oxidant modelAnti-oxidant model
Fresh fruit and vegetablesSource of carotenoidsHerbs and spices, tea, wine
Dietary advice
Le réflexe Oxybiane
Advice on supplements
Le réflexeProteochoc
Perturbed cellular protection
From the very first symptoms of…
INFLAMMATIONINFECTION
2 situations
Lip and genital herpes
Mouth ulcers
Tooth abscess
Flu-like symptoms Trauma, bruising
Burns, sunburn
Sprains
Joint pain
Regimen: 4 capsules a day for 3 days
Think Proteochoc
Like certain other algae and plants, the seaweed Porphyra umbilicalis can survive under extremely harsh conditions
Porphyral extract was added to the first Oxybiane composition in 1993 (?), for its anti-oxidant and anti-elastase properties.
In 1995, Dr Paul Bringer and Dr Jean-Louis Lichon observed the effects of Oxybiane on dry eyes and cataracts, suggesting that the product, and in particular Porphyral, might have other properties.
About Proteochoc
P.U. type plants and algae are known to have the ability to
synthesise HSP rapidly
= In 1999, PiLeJe became involved in a stress protein modulator development project.
= Meeting with HSP specialist Professor André Patrick ARRIGO* (CNRS LYON 1). He suggested that Porphyral had a HSP-modulating effect.
= Research projects began
*Médecines/Sciences n°1, vol 14, janvier 1998
About Proteochoc
2- Porphyral HSP* reduces UV ray-induced DNA damage
Effects of a Porphyral HSP® extract on the DNA damage induced by UV rays
Ligh
t int
ensit
y (R
LU) a
s a
prop
ortio
n of
num
ber o
f DNA
lesio
ns
0
200
400
Control without UV
Porphyra 0.1% Porphyra1.3%
1- Porphyral HSP* boosts anti-free radical resistance
0
50
100
150
200
250
300
0 0,1 0,2 0,5 1 2 5 10concentration (g/L)
Global antioxidant potential of Porphyral HSP® - KRL test-
Incr
ease
in a
nti-f
ree
radi
cal r
esist
ance
(%
cont
rol b
lood
)
The different studies
Porphyral HSP
Témoin
Augmentation des HSP 27, 60, 70Plus rapide pour 27 et 60
3- Porphyral HSP* stimulates HSP production after thermal shock
Protocol evaluating the modulatory effects of Porphyra umbilicalis on stress protein synthesis
These studies were presented at the 4th Micronutrition Symposium in March 2002 by Flore MARTIN, head of the scientific department
PiLeJe patents the Porphyra umbilicalis extraction process
under the name Porphyral HSP*