(Cell Membrane) - wun-ching.com.t · PDF file第1 章 細 胞 3 細胞膜的成分─包含磷脂質(phospholipids)、蛋白質、碳水化合物及膽固醇等。 其中蛋白質含量最高為55%

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  • 1

    1-1

    1-2

    1-3

  • 2

    (cell

    membrane)(cytoplasm)(organelles) 1-1

    1-1

    1-1

    (Cell Membrane)

    1972 (S. J. Singer) (G. L.

    Nicholson) (fluid-mosaic model)

    1.

    2. 1-2

    3.

  • 1

    3

    (phospholipids)

    55% 25%

    (glycoproteins) (glycolipids)

    1-2

    1-2

    1.

    2.

    (selective permeability)

    3. (signal transduction)

    4. (cell

    junction)

  • 4

    (Cytoplasm) (intracellular

    fluid)

    75~90%

    (cytoskeleton)

    (Organelles)

    (Nucleus)

    DNA

    (nuclear membrane)(nucleole)

    (nucleoplasm)(chromatin) 4 1-3

    1. (nuclear

    pore)

    1-3

  • 1

    5

    2. DNARNA RNA (ribosomal

    RNA, rRNA) RNA

    3.

    4. (histones) DNA

    (chromosome) 1-4

    1-4

  • 6

    (Ribosome)

    (rRNA)

    1-5

    1. (attached ribosome)

    2. (free ribosome)

    (Endoplasmic Reticulum, ER)

    1-6

    1-6

    1-5

  • 1

    7

    1. (granular or rough ER, rER)

    2. (agranular or smooth ER, sER)

    (Golgi Apparatus)

    3~8

    1-7

    1. (glycosylation)

    1-7

  • 8

    2.

    1-7

    (Lysosomes)

    1-8

    (autolysis)

    (osteoclast)

    (osteoblast) A

    1-8

  • 1

    9

    (Mitochondria)

    ATP

    DNA (mitochondrial DNA)

    1-9 DNA

    1-9

    (Microtubules and Microfilaments)

    (microfilament)(intermediate filament)(microtubule)

    (cytoskeleton) 1-10

    1. 3~12 nm (actin)

    (myosine)

    2. 18~30 nm(tubulin)

  • 10

    3. 7~11 nm(thick filaments)

    1-10

    (Peroxisomes)

    (catalase)

    2 2 2 2H O H O 1/ 2 O

    (Centorosome and Centrioles)

    9

    1-11

  • 1

    11

    1-11

    (Cilia and Flagella)

    9 2

    1-12

    1-12

  • 12

    1-2 (Cell Division)

    (cell cycle)

    (interphase)(mitosis) 1-13

    G1gap phase1 1S (synthesis phase, S phase)G2gap phase 2

    2 S G1S DNA

    S G2

    1-13 M

    (mitosis)(meiosis)

  • 1

    13

    (Mitosis)

    1-14 1-1

    1-14

  • 14

    1-1

    (Prophase) 1.

    2.

    (Metaphase)

    (Anaphase) 2~10

    (Telophase) 1.

    2.

    3. (cytokinesis)

    (Meiosis) (gamete)

    (spermatogonium)

    (oogenesis)

    I (meiosis I)

    II (meiosis II)

    I

    I I I I I 1-15

    1. I

    (synapsis)(tetrad)

    (crossing-over)

    1-16

    2. I

  • 1

    15

    1-15

  • 16

    3. I

    4. I

    1-16

    II

    II II II II II

    1-17 1-2

    1-17

  • 1

    17

    1-2

    (Mitosis) (Meiosis)

    (Apoptosis)

    (programmed cell death)

    (apoptotic body)

    1-3

    (passive

    transport)(active transport) 1-3

    1-3

    ATP ATP

    1. (Na+-K+ pump)

    2.

  • 18

    (Passive Transport) ATP

    (simple diffusion)

    (facilitated diffusion)(osmosis)(filtration)

    1-18

    1-18

    (Osmosis)

  • 1

    19

    1-19

    1.

    2. 1-19

    (isotonic) 0.9% NaCl

    0.9% NaCl

    (hypertonic) 0.9% NaCl

    (hypotonic)

    (Filtration)

    10 10-11

    (Active transport)

    (primary active transport)(secondary active transport)

    (Na+-K+ pump) ATPase ATP

    3 Na+ 2 K+

    K+ Na+

  • 20

    ATP

    Na+ 12 12-12

    1. (phagocytosis)

    2. (pinocytosis)

    3. (receptor-mediated endocytosis)

    (low density lipoprotein, LDL)

    LDL LDL

    4. (exocytosis)