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CURRICULUM VITAE October 5, 2018 NAME: YING, Gui-shuang OFFICE ADDRESS: 3535 Market Street, Suite 700 Philadelphia, Pennsylvania 19104-3309 Email: [email protected] TELEPHONE: (610) 645-0836 -Home (215) 615-1514 –Work PLACE OF BIRTH: Zhejiang, P. R. China Visa Status/Citizenship Permanent Resident of United States / P. R. China EDUCATION: 1988-1993 M.D., Zhejiang Medical University (Preventive Medicine) 1993-1996 M.P.H., Zhejiang Medical University (Toxicology) 1998-2000 M.S., University of Michigan School of Public Health (Biostatistics) 2000-2004 Ph.D., University of Pennsylvania School of Medicine (Biostatistics) ACADEMIC APPOINTMENTS: 2013- Associate Professor (Clinician-Educator Track), Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Perelman School of Medicine 2004 - 2013 Assistant Professor (Clinician-Educator Track, 10-Years Appointment), Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Perelman School of Medicine 2004- Director, Biostatistics Consulting Service, Center for Preventive Ophthalmology and Biostatistics, Department of Ophthalmology, University of Pennsylvania, Perelman School of Medicine 2005- Associate Scholar, Biostatistics Department Center for Clinical Epidemiology and Biostatistics University of Pennsylvania, Perelman School of Medicine 2005- Faculty Member, Graduate Group in Epidemiology & Biostatistics Biomedical Graduate Studies Program University of Pennsylvania, Perelman School of Medicine 2008- Faculty member, Institute for Translational Medicine and Therapeutics

CURRICULUM VITAE October 5, 2018 YING · 5.10.2018  · CURRICULUM VITAE October 5, 2018 NAME: YING, Gui-shuang OFFICE ADDRESS: 3535 Market Street, Suite 700 Philadelphia, Pennsylvania

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Page 1: CURRICULUM VITAE October 5, 2018 YING · 5.10.2018  · CURRICULUM VITAE October 5, 2018 NAME: YING, Gui-shuang OFFICE ADDRESS: 3535 Market Street, Suite 700 Philadelphia, Pennsylvania

CURRICULUM VITAE October 5, 2018

NAME: YING, Gui-shuang OFFICE ADDRESS: 3535 Market Street, Suite 700

Philadelphia, Pennsylvania 19104-3309 Email: [email protected]

TELEPHONE: (610) 645-0836 -Home

(215) 615-1514 –Work PLACE OF BIRTH: Zhejiang, P. R. China Visa Status/Citizenship Permanent Resident of United States / P. R. China EDUCATION: 1988-1993 M.D., Zhejiang Medical University (Preventive Medicine)

1993-1996 M.P.H., Zhejiang Medical University (Toxicology) 1998-2000 M.S., University of Michigan School of Public Health (Biostatistics) 2000-2004 Ph.D., University of Pennsylvania School of Medicine (Biostatistics) ACADEMIC APPOINTMENTS: 2013- Associate Professor (Clinician-Educator Track), Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Perelman School of Medicine 2004 - 2013 Assistant Professor (Clinician-Educator Track, 10-Years Appointment), Department of

Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Perelman School of Medicine 2004- Director, Biostatistics Consulting Service, Center for Preventive Ophthalmology and Biostatistics, Department of Ophthalmology, University of Pennsylvania, Perelman School of Medicine 2005- Associate Scholar, Biostatistics Department Center for Clinical Epidemiology and Biostatistics University of Pennsylvania, Perelman School of Medicine 2005- Faculty Member, Graduate Group in Epidemiology & Biostatistics Biomedical Graduate Studies Program University of Pennsylvania, Perelman School of Medicine 2008- Faculty member, Institute for Translational Medicine and Therapeutics

Page 2: CURRICULUM VITAE October 5, 2018 YING · 5.10.2018  · CURRICULUM VITAE October 5, 2018 NAME: YING, Gui-shuang OFFICE ADDRESS: 3535 Market Street, Suite 700 Philadelphia, Pennsylvania

HONORS AND AWARDS: 1989-1993 Scholarship from Zhejiang Medical University

1993 Best Bachelor Thesis Award from Zhejiang Medical University

1993 Outstanding Graduate Award from Zhejiang Medical University

1994-1995 Graduate Fellowship from Graduate School of Zhejiang Medical University

2007 McCabe Pilot Award to research “Optimal prediction of patient accrual, trial length and cost in randomized clinical trials”, University of Pennsylvania

2008 The ARVO Foundation for Eye Research/ Retina Research Foundation/

Joseph M. and Eula C. Lawrence Travel Scholarship Travel Grant 2016 American Academy of Ophthalmology’s Achievement Award PROFESSIONAL EXPERIENCE: 1993-1996 Research Assistant, Department of Toxicology, Zhejiang Medical University 1996-1998 Research Assistant, Institute of Disability and Human Development, School of Public Health, University of Illinois at Chicago 1998 Teacher Assistant, Department of Biostatistics, School of Public Health, University of

Michigan 1999 (Summer) Biostatistician Internship, Department of Biostatistics, STATPROBE Inc. 1999-2000 Research Assistant, Department of Environmental Health Sciences,

School of Public Health, University of Michigan 2000- 2004 Biostatistician, Clinical Trials Coordinating Center, Department of Ophthalmology, University of Pennsylvania School of Medicine 2004- Senior Biostatistician, Clinical Trials Coordinating Center, Department of Ophthalmology, University of Pennsylvania School of Medicine MEMBERSHIPS IN PROFESSIONAL AND SCIENTIFIC SOCIETIES: 2001- Society for Clinical Trials, Member 2001- Association for Research in Vision and Ophthalmology, Member

2003- American Statistical Association, Member 2003- The International Biometrics Society, Member 2009 Grant Reviewer, Juvenile Diabetes Research Foundation

2012-2015 Data Safety Monitoring Committee (DSMB) member for a NIH-funded clinical trial “Anastrozole in Patients with Pulmonary Arterial Hypertension (AIPH) study” 2013- 2014 Data Safety Monitoring Committee (DSMB) member for “Transcorneal electrical

Page 3: CURRICULUM VITAE October 5, 2018 YING · 5.10.2018  · CURRICULUM VITAE October 5, 2018 NAME: YING, Gui-shuang OFFICE ADDRESS: 3535 Market Street, Suite 700 Philadelphia, Pennsylvania

stimulation for the treatment of retinitis pigmentosa – a safety and efficacy NSR device study ”

2008- Grant Reviewer, National Eye Institute 2018 Scientific Reviewer for Vision Research Program of U.S. Army Medical Research 2018 Grant reviewer for Wellcome Trust EDITORIAL POSITIONS:

Reviewer:

2002- Ophthalmology

2006- Archives of Ophthalmology

2007- Diabetes Care

2008- The American Statistician

2009- Journal of American Association for Pediatric Ophthalmology and Strabismus

2009- Clinical Ophthalmology

2009- Clinical Intervention in Aging, Clinical Medicine: Therapeutics

2010- Statistics in Medicine

2011- Investigative Ophthalmology & Visual Science 2011- Pharmaceutical Statistics

2011 - Biometrical Journal

2011- Diabetes

2011- Clinical Trials

2011- Contemporary Clinical Trials

2012- BMC Research Notes

2012- Ophthalmic & Physiological Optics

2012- Expert Review of Clinical Pharmacology

2012- BMC Medical Research Methodology

2012 - Ophthalmic Epidemiology

2012- International Journal of Ophthalmology

2012- Journal of Biopharmaceutical Statistics

2013- Current Medical Research & Opinion

2013- PLOS ONE

2013- Advance in Therapy

2015- Retina

2015- Communications in Statistics – Case Studies and Data Analysis

2015- British Journal of Ophthalmology

Page 4: CURRICULUM VITAE October 5, 2018 YING · 5.10.2018  · CURRICULUM VITAE October 5, 2018 NAME: YING, Gui-shuang OFFICE ADDRESS: 3535 Market Street, Suite 700 Philadelphia, Pennsylvania

2015- Immunotherapy

2015- Medicine

2017- JCO Clinical Cancer Informatics

2018- JAMA

2011 Book Editor for the book titled "Age Related Macular Degeneration",

ISBN: 978-953-307-591-4.

Editorial Board:

2012- Journal of Medical Sciences

2012- Dataset Papers in Medicine

2013- International Journal of Ophthalmology (Expert Board)

2014- Ophthalmic Epidemiology

2016- Advances in Therapy

COMMITTEE MEMBERSHIPS:

Executive Committee member, Vision in Preschoolers (VIP) Study. 2004 – 2007. Operation Committee member, Comparison of AMD Treatment Trials (CATT) Study Group. 2011-2018 Executive Committee member, Telemedicine approaches to evaluating acute-phase ROP. 2010-2016 Executive Committee member, Postnatal growth and retinopathy of prematurity (G-ROP). 2012- 2014 ENAR Distinguished Student Paper Awards Committee member. 2015 ENAR Distinguished Student Paper Awards Committee member. 2016 ENAR Distinguished Student Paper Awards Committee member. 2016, 2017 Mentor in the ARVO Global Mentorship Program. 2018-2019 Preferred Practice Patterns Committee Member (Retina/Vitreous Panel) Organizing Roles in Scientific Meetings: Jul, 2008 Section Chair. The First International Symposium on Biopharmaceutical

Statistics. Shanghai, P.R.China

Mar, 2011 Advisory Committee and Section co-Chair. International Conference on Good Medical Research. Istanbul, Turkey

Apr, 2011 Short Course Organizer. Annual Meeting of Association for Research in Vision and Ophthalmology (ARVO) Fort Lauderdale

Mar, 2012 Organizing Committee Member, and Section co-chair for International Conference on Biometrics and Biostatistics. Omaha, Nebraska

Page 5: CURRICULUM VITAE October 5, 2018 YING · 5.10.2018  · CURRICULUM VITAE October 5, 2018 NAME: YING, Gui-shuang OFFICE ADDRESS: 3535 Market Street, Suite 700 Philadelphia, Pennsylvania

May, 2015 Section Moderator for Paper session at 2015 ARVO Annual Meeting. Seattle, Washington.

July 30, 2018 Short Course co-organizer and Presenter on “Prediction in Event-based Clinical Trials”. Joint Statistical Meeting, Vancouver, British Columbia,

Canada. PUBLICATIONS: Research Publications, peer reviewed: 1. Schenk M, Schwartz AG, O’Neal E, Kinnard M, Greenson JK, Fryzek JP, Ying GS, Garabrant DH. Familial risk of

pancreas cancer. J Natl Cancer Inst 2001;93:640-4. 2. Garabrant DH, Roth HD, Parsad R, Ying GS. Latex sensitization in health care workers and in the U.S. general population.

Am J Epidemiol 2001;153:515-21. 3. Aleman TS, LaVail MM, Montemayor R, Ying GS, Maguire MG, Laties AM, Jacobson SG, Cideciyan AV. Augmented

rod bipolar cell function in partial photoreceptor loss: an ERG study in P23H rhodopsin transgenic and aging normal rats. Vision Research 2001;41:2779-97.

4. Dunaief JL, Dentchev T, Ying GS, Milam AH. The role of apoptosis in age-related macular degeneration. Arch

Ophthalmol 2002;120:1435-42.

5. Loman J, Quinn GE, Kamoun L, Ying GS, Maguire MG, Hudesman D, Stone RA. Darkness and near work: myopia and its progression in third-year law students. Ophthalmology 2002;109:1032-8.

6. Heller T, Ying GS, Rimmer JS, Marks BA. Determinants of exercise in adults with cerebral palsy. Public Health Nurs

2002;19:223-31. 7. Vannas AE, Ying GS, Stone RA, Maguire MG, Jormanainen V, Tervo T. Myopia and natural lighting extremes: risk

factors in Finnish army conscripts. Acta Ophthalmol Scand 2003;81:588-95. 8. Hahn P, Lindsten T, Ying GS, Bennett J, Milam AH, Thompson CB, Dunaief JL. Proapoptotic Bcl-2 family members,

Bax and Bak, are essential for developmental photoreceptor apoptosis. Invest Ophthalmol Vis Sci 2003;44:3598-605. 9. Quinn GE, Francis EL, Nipper KS, Flitcroft DI, Ying GS, Rees R, Schmid G, Maguire MG, Stone RA. Highly precise

eye length measurements in children aged 3 through 12 years. Arch Ophthalmol 2003;121:985-90. 10. Prenner JL, Rosenblatt BJ, Tolentino MJ, Ying GS, Javornik NB, Maguire MG, Ho AC, the CNVPT Research Group.

Risk factors for choroidal neovascularization and vision loss in the Fellow Eye Study of CNVPT. Retina 2003;23:307-14..

11. Balcer LJ, Baier ML, Cohen JA, Kooijmans MF, Sandrock AW, Nano-Schiavi L, Pfohl DC, Mills M, Bowen J, Ford

C, Heidenreich FR, Jacobs DA, Markowitz CE, Stuart WH, Ying GS, Galetta SL, Maguire MG, Cutter CR. Contrast letter acuity as a visual component for the Multiple Sclerosis Functional Composite. Neurology 2003;61:1367-73.

12. Lee MS, Balcer LJ, Volpe NJ, Liu GT, Ying GS, Galetta SL. Laser pointer visual field screening. Neuroophthalmol

2003;23:260-3. 13. Stone RA, Quinn GE, Francis EL, Ying GS, Flitcroft DI, Parekh P, Brown J, Orlow J, Schmid G. Diurnal axial length

fluctuations in human eyes. Invest Ophthalmol Vis Sci 2004;45:63-70.

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PUBLICATIONS - Research Publications, peer reviewed (Continued): 14. Ying GS, Heitjan DF, Chen T. Nonparametric prediction of event times in randomized clinical trials. Clinical Trials

2004;1:352-61. 15. Ibarra MS, Hsu J, Mirza N, Wu I-H, Ying GS, Mainster MA, Tolentino MJ. Retinal temperature increase during

transpupillary thermotherapy: effects of pigmentation, subretinal blood, and choroidal blood flow. Invest Ophthalmol Vis Sci 2004;45:3678-82.

16. Hahn P, Lindsten T, Lyubarsky A, Ying GS, Pugh EN, Thompson CB, Dunaief JL. Deficiency of Bax and Bak

protects photoreceptors from light damage in vivo. Cell Death and Differentiation 2004;11:1192-7. 17. Metelisina TI, Grunwald JE, Dupont JC, Ying GS. Effects of Niacin on the choroidal circulation of patients with Age-

related Macular Degeneration. British Journal of Ophthalmology 2004;88:1568-72. 18. Roman AJ, Schwartz SB, Alman TS, Cideciyan AV, Chico JD, Windsor E, Gardner LM, Ying GS, Smilko EE,

Maguire MG, Jacobson SG. Quantifying rod photoreceptor-mediated vision in retinal degenerations: dark-adapted thresholds as outcome measures. Experimental Eye Research 2005;80:259-72.

19. Grunwald JE, Metelitsin TI, DuPont JC, Ying GS, Maguire MG. Reduced foveolar choroidal blood flow in eyes with

increasing AMD severity. Invest Ophthalmol Vis Sci 2005;46:1033-8. 20. Heidary G, Ying GS, Maguire MG, Young TL. The impact of sphere on cylinder type and severity in a high myopia

cohort. Optom Vis Sci 2005;82:244-7. 21. Metelitsina TI, Grunwald JE, DuPont JC, Ying GS. Effect of Viagra on the ocular circulation of AMD patients.

Experimental Eye Research 2005;81:159-64. 22. Kupersmith MJ, Ying GS. Ocular motor dysfunction in ocular myasthenia gravis: effects of treat. British Journal of

Ophthalmology 2005;89:1330-4. 23. Metelitsina TI, Grunwald JE, DuPont JC, Ying GS. Effect of systemic hypertension on foveolar choroidal blood flow

in age rated macular degeneration (AMD). British Journal of Ophthalmology 2006;90:342-6. 24. Metelitsina TI, Grunwald JE, DuPont JC, Ying GS, Liu CC. Effect of Viagra on the retinal vein diameter in AMD

patients. Experimental Eye Research 2006;83:128-32. 25. Wilson LB, Quinn GE, Ying GS, Francis EL, Schmid G, Lam A, Orlow J, Stone RA. The relation of axial length and

intraocular pressure fluctuations in human eyes. Invest Ophthalmol Vis Sci 2006;47:1778-84. 26. Komaromy AM, Garg CD, Ying GS, Liu CC. The effect of head position on intraocular pressure in horses. American

Journal of Veterinary Research 2006;67:1232-5. 27. Stone RA, Wilson LB, Ying GS, Liu CC, Criss JS, Orlow J, Lindstrom JM, Quinn GE. Associations between

Childhood Myopia and Parental Smoking. Invest Ophthalmol Vis Sci 2006;47:4277-87. 28. Tania TY, Mills MD, Beck AD, Joos KM, Ying GS, Liu CC, Piltz-Seymour JR. Central Corneal Thickness and

Corneal Diameter in Patients with Childhood Glaucoma. Journal of Glaucoma 2006;15:524-8. 29. Hahn P, Ying GS, Beard J, Dunaief JL. Iron levels in human retina: sex difference and increase with age. Neuroreport

2006;17:1803-6.

Page 7: CURRICULUM VITAE October 5, 2018 YING · 5.10.2018  · CURRICULUM VITAE October 5, 2018 NAME: YING, Gui-shuang OFFICE ADDRESS: 3535 Market Street, Suite 700 Philadelphia, Pennsylvania

PUBLICATIONS - Research Publications, peer reviewed (Continued): 30. Rabinowitz MP, Grunwald JE, Karp KA, Quinn GE, Ying GS, Mills MD. Progression to severe retinopathy predicted

by retinal vessel diameter between 31 and 34 weeks of postconception age. Archives of Ophthalmology 2007;125:1495-500.

31. Orlin A, Mills MD, Ying GS, Liu CC. A Comparison of Hang-Back with Conventional Recession Surgery for

Exotropia. J AAPOS 2007;11:597-600. 32. Cote ML, Schenk M, Schwartz AG, Vigneau FD, Kinnard M, Greenson JK, Fryzek JP, Ying GS, Garabrant DH. Risk

of other cancers in individuals with a family history of pancreas cancer. Journal of Gastrointestinal Cancer 2007;38:119-26.

33. Ying GS, Heitjan DF. Weibull Prediction of Event Times in Randomized Clinical Trials. Pharmaceutical Statistics

2008;7:107-20. 34. Metelitsina TI, Grunwald JE, Dupoint JC, Ying GS, Brucker AJ, Dunaief JL. Foveolar choroidal blood flow and choroidal

neovascularization in age-related macular degeneration. Invest Ophthalmol Vis Sci 2008;49:358-63.

35. Greller AL, Hoffman AB, Liu C, Ying GS, Vudathala D, Acland GM, Komáromy AM. Effects of the topically applied calcium-channel blocker flunarizine on intraocular pressure in clinically normal dogs. Am J Vet Res 2008;69:273-8.

36. Ranchod TM, Guercio JR, Ying GS, Brucker AJ, Stoltz RA. Effect of aspirin therapy on photodynamic therapy with

verteporfin for choroidal neovascularization. Retina 2008;28:711-6. 37. Skalet AH, Quinn GE, Ying GS, Gordillo L, Dodobara L, Cocker K, Fielder AR, Ells AL, Mills MD, Wilson C.

Gilbert C. Telemedicine screening for Retinopathy of Prematurity (ROP) in developing countries using digital retinal images: A feasibility project. J AAPOS 2008;12:252-8.

38. Zaveri M, Conger A, Salter A, Frohman TC, Galetta SL, Markowitz CE, Jacobs DA, Cutter GR, Ying GS, Maguire

MG, Calabresi PA, Balcer LJ, Frohman EM. Retinal Imaging by Laser Polarimetry and Optical Coherence Tomography Evidence of Axonal Degeneration in Multiple Sclerosis. Archives of Neurology 2008;65:924-8.

39. Ying GS, Maguire MG, Liu CC, Antoszyk A, and Complications of Age-related Macular Degeneration Prevention Trial

Research Group. Night vision and progression of Age-related Macular Degeneration in the Complications of Age-related Macular Degeneration Prevention Trial. Ophthalmology 2008;115:1876-82.

40. Brown JS, Flitcroft DI, Ying GS, Francis EL, Quinn GE, Stone RA. In Vivo human choroidal thickness

measurements: Evidence of diurnal fluctuations. Invest Ophthalmol Vis Sci. 2009;50:5-12. 41. Okeke CO, Quigley HA, Jampel HD, Ying GS, Plyler RJ, Jiang YZ, Friedman DS. Adherence with Topical Glaucoma

Medication Monitored Electronically: The Travatan Dosing Aid Study. Ophthalmology 2009;116:191-9. 42. Lukinova N, Iacovelli J, Dentchev T, Wolkow N, Hunter A, Amado D, Ying GS, Sparrow J, Dunaief JL. Iron

chelation protects the retinal pigment epithelial cell line ARPE-19 against cell death triggered by diverse stimuli. Invest Ophthalmol Vis Sci. 2009;50:1440-7.

43. Ranchod TM, Brucker AJ, Liu CC, Cukras CA, Hopkins TB, Ying GS. Evaluation of actual versus expected PDT spot

size. Am J Ophthalmol. 2009;147:859-64. 44. Friedman DS, Okeke CO, Jampel HD, Plyler RJ, Ying GS, Jiang YZ, Quigley HA. Risk factors of poor adherence

with eyedrops in electronically monitored glaucoma patients. Ophthalmology 2009;116:1097-1105.

Page 8: CURRICULUM VITAE October 5, 2018 YING · 5.10.2018  · CURRICULUM VITAE October 5, 2018 NAME: YING, Gui-shuang OFFICE ADDRESS: 3535 Market Street, Suite 700 Philadelphia, Pennsylvania

PUBLICATIONS - Research Publications, peer reviewed (Continued): 45. Grunwald L, Mills MD, Johnson K, Karp KA, Quinn GQ, Ying GS, Grunwald JE. Does change in retinal vessel

diameter predict severe retinopathy of prematurity? Am J of Ophthalmol 2009;147:1086-1091. 46. Hahn P, Song Y, Ying GS, He X, Beard J, Dunaief JL. Age-dependent and gender-specific changes in mouse tissue

iron by strain. Experimental Gerontology 2009;44:594-600. 47. Iacovelli J, Mlodnicka AE, Veldman P, Ying GS, Dunaief JL, Schumacher A. Brain and retinal ferroportin 1

dysregulation in polycythaemia mice. Brain Res. 2009;1289:85-95. 48. Ying GS, Maguire MG, Alexander J, Martin R, Antoszyk A. Description of the AREDS 9-step severity scale applied

to participants in CAPT. Archives of Ophthalmology 2009;127:1147-51. 49. Shah DN, Wilson C, Ying GS, Karp K, Fielder A, Ng J, Mills MD, Quinn GE. Semi-automated digital image analysis

of posterior pole vessels in retinopathy of prematurity. J APPOS 2009;13:504-6. 50. Shah DN, Karp K, Ying GS, Mills MD, Quinn GE. Image analysis of posterior pole vessels identifies type I

retinopathy of prematurity. J APPOS 2009;13:507-8. 51. Volpe NJ, Dadvand L, Kim SK, Maguire MG, Ying GS, Moster ML, Galetta SL, M. D. Computerized Binocular

Pupillography of the Swinging Flashlight Test Detects Afferent Pupillary Defects. Current Eye Research 2009;34:606-13.

52. Maguire AM, High KA, Auriccho A, Wright JF, Pierce EA, Testa F, Mingozzi F, Bennicelli J, Ying GS, Rossi S,

Marshall KA, Banfi S, Chung D, Morgan JA, Hauck B, Zelanaia O, Zhu X, Raffini L, Coppieters F, Elfride DB, Schindler K, Volpe N, Surace EM, Acerra C, Lyubarsky A, Redmond TM, Stone E, Sun J, McDonnell JW, Leroy BP, Simonelli F, Bennett J. Phase I gene therapy shows reversal of congenital blindness: Age-dependent effect of treatment. Lancet 2009;374:1597-605.

53. Maguire MG, Ying GS, McCannel C, Liu CC. Dai Y. Statin use and the incidence of advanced age-related macular

degeneration in the Complications of Age-related Macular Degeneration Prevention Trial (CAPT). Ophthalmology 2009;116:2381-5.

54. Okeke CO, Quigley HA, Jampel HD, Ying GS, Plyler RJ, Jiang YZ, Friedman DS. Interventions Improve Poor

Adherence with Once Daily Glaucoma Medications in Electronically Monitored Patients. Ophthalmology: 2009;116:2286-93.

55. Garcia MM, Ying GS, Cocores CA, Tanaka JC, Komaromy AM. Behavioral method form objective vision testing and

identification of achromatopsia in dogs. Am J Vet Res 2010;71:97-102.

56. Simonelli F, Maguire AM, Testa F ,Pierce EA, Mingozzi F, Bennicelli J, Rossi S, Marshall K, Banfi S, Surace EM, Sun J, Redmond M, Zhu X, Shindler KS, Ying GS, Ziviello C, Acerra C, Wright JF, DcDonnel JW, High KA, Bennett J, Auricchio A. Gene therapy for Leber’s congenital amaurosis is safe and effective through 1.5 years after vector administration. Molecular Therapy 2010;18:643-50.

57. Zaida AA, Ying GS, Daniel E, Gangaputra S, Rosenbaum JT, Suhler EB, Throne JE, Foster CS, Jabs DA, Levy-

Clarke GA, Nussenblatt RB, Kempen JH. Hypopyon in patients with uveitis. Ophthalmology 2010;117:366-72. 58. Cyert L, Ying GS, Dobson V, Quinn G, Magure M, Kulp MT, Ciner E, Schmidt P, Moore B, and Vision in Preschoolers

(VIP) Study Group. Age Comparison for Lea Symbols and HOTV in Preschool Vision Screening. Optom Vis Sci 2010;87:87-95.

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PUBLICATIONS - Research Publications, peer reviewed (Continued): 59. Ghodasra DH, Karen KA, Ying GS, Mills MD, Wilson C, Fielder AR, Ng J, Quinn GE. Risk stratification of eyes

with preplus ROP by semi-automated analysis of digital images. Arch Ophthalmol. 2010;128:719-23. 60. Talman LS, Sackel D, Long DA, Bisker ER, Ratchford JN, Farrell SK, Loguidice MJ, Conger A, Frohman TC, Jacobs

DA, Markowitz CE, Cutter GR, Ying GS, Dai Y, Maguire MG, Galetta SL, Frohman EM, Calabresi PA, Balcer LJ. Longitudinal study of vision and retinal nerve fiber layer thickness in MS. Ann Neurol 2010;67:749-60.

61. Xu W, Grunwald JE, Metelitsina TI, DuPont JC, Ying GS, Martin ER, Dunaief JL, Brucker AJ. Risk factors for

choroidal neovascularization in AMD are associated with decreased foveolar choroidal circulation. Am J of Ophthalmol 2010;150:40-47.

62. Stone RA, Ying GS, Pearson DJ, Dansal M, Puri M, Miller E, Alexander J, Piltz J, Nyberg W, Maguire MG, Eledath

J, Sawhney H. Utility of dignitial stereo images for optic disc evaluation. Invest Ophthalmol Vis Sci 2010;51:5667-5674.

63. Metelitsina TI, Grunwald JE, DuPont JC, Ying GS. Effect of isometric exercise on choroidal blood flow in patients

with age-related macular degeneration (AMD). British Journal of Ophthalmology 2010;94:1629-31. 64. Ying GS, Maguire MG, and the CAPT Research Group. Development of a Risk Score for Geographic Atrophy (GA)

in Complications of Age-Related Macular Degeneration Prevention Trial (CAPT). Ophthalmology 2011;118:332-8. 65. Tamhankar MA, Kim JH, Ying GS, Volpe NJ. Adult hypertropia: a guide to diagnostic evaluation based on review of

300 patients. Eye 2011;25:91-6. 66. Binenbaum G, Ying GS, Quinn GE, Dreiseitl S, Karp K, Roberts RS, Kirpalani H, and the Premature Infants in Need

of Transfusion Study Group. A Clinical prediction model to stratify ROP risk using postnatal weight gain. Pediatrics 2011;127:607-614.

67. Tamhankar MA, Ying GS, Volpe NJ. Effectiveness of prisms in the management of diplopia due to fourth nerve palsy.

J Neuroophthalmology 2011;31:206-9. 68. Shah DN, Wilson CM, Ying GS, Karp KA, Cocker KD, Fielder A, Mill MD, Quinn EQ. Comparison of expert graders

to computer assisted image analysis of the retina in Retinopathy of Prematurity. Br J Ophthalmol. 2011;95:1442-5. 69. Jensen AK, Ying GS, Huang JY, Karp K, Quinn GE, Binenbaum G. Thrombocytopenia and retinopathy of

prematurity. J APPOS 2011;15:e3-e4. 70. Smolen H, Ying GS, Martin ER, Maguire MG. New grading criteria allow for earlier detection of geographic atrophy

in clinical trials. Invest Ophthalmol Vis Sci. 2011;52:9218-25. 71. Ying GS, Maguire MG, Quinn G, Kulp MT, Cyert L, and Vision in Preschoolers (VIP) Study Group. ROC analysis of

the accuracy of noncycloplegic retinoscopy, Retinomax autorefractor and SureSight Vision Screener for Preschool vision screening. Invest Ophthalmol Vis Sci 2011;52:9658-64.

72. Berenberg TL, Metelitsina TI, Madow B, Dai Y, Ying GS, DuPont JC, Grunwald L, Brucker AJ, Grunwald JE. The

association between drusen extent and foveolar choroidal blood flow in age-related macular degeneration. Retina 2012;32:25-31.

73. Bennett J, Ashtari M, Wellman J, Marshall KA, Cyckowski LL, Chung DC, McCague S, Pierce EA, Chen Y,

Bennicelli JL, Zhu X, Ying GS, Sun J, Wright JF, Auricchio A, Simonelli F, Shindler KS, Mingozzi F, High KA, Maguire AM. AAV2 gene therapy readministration in three adults with Congenital blindness. Science Translational Medicine 2012;4:120ra15.

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PUBLICATIONS - Research Publications, peer reviewed (Continued): 74. Tamhankar MA, Ying GS, Volpe NJ. Effectiveness of prisms in the management of diplopia in patients due to diverse

etiolgies. J Pediatric Ophthalmology & Strabismus 2012;49:222-8. 75. Mehta SM, Loevner LA, Mikityansky I, Langlotz C, Ying GS, Tamhankar MA, Shindler K, Volpe NJ.The diagnostic

and economic yield of neuroimaging in neuro-ophthalmology. J Neuroophthalmol. 2012;32:139-144. 76. Charkoudian LD, Ying GS, Pujari SS, Gangaputra S, Thorne JE, Foster CS, Jabs DA, Levy-Clarke GA, Nussenblatt

RB, Rosenbaum JT, Suhler EB, Kempen JH. High-dose intravenous corticosteroids for ocular inflammatory diseases. Ocul Immunol Inflamm 2012;20:91-99.

77. Udoetuk JD, Dai Y, Ying GS, Daniel E, Gangaputra S, MD, MPH, Rosenbaum JT, Kempen JH.

Risk of corticosteroid-induced hyperglycemia requiring medical therapy among patients with inflammatory eye diseases. Ophthalmology 2012;119:1569-74.

78. Hunter A, Spechler PA, Cwanger A, Song Y, Zhang Z, Ying GS, Hunter AK, deZoeten E, Dunaief JL. DNA

Methylation is associated with altered gene expression in AMD. Invest Ophthalmol Vis Sci. 2012;53:2089-105.

79. Grunwald JE, Ying GS, Maguire M, Pistilli M, Daniel E, Alexander J, Whittock-Martin R, Parker C, Mohler E, Lo JC, Townsend R, Gadegbeku CA, Lash JP, Fink JC, Rahman M, Feldman H, Kusek JW, Xie D, Coleman M, Keane MG and CRIC Study Group. Association between retinopathy and cardiovascular disease in patients with Chronic Kidney Disease: Findings from the Chronic Renal Insufficiency Cohort (CRIC) Study. Am J Cardiol. 2012;110:246-53.

80. Tamhankar MA, Ying GS, Volpe NJ. Prisms are effective in resolving diplopia from incomitant, large and combined strabismus. Eur J Ophthalmol. 2012;22:890-7.

81. Shindler KS, Revere K, Dutt M, Ying GS, Chung DC. In Vivo detection of experimental optic neuritis by pupillometry.

Experimental Eye Research 2012;100:1-6. 82. Kwon JY, Ghodasra DH, Ying GS, Wilson CM, Karp KA, Huang JY, Mills MD, Fielder AR, Quinn GE. Retinal

vessel changes after laser treatment for retinopathy of prematurity. J APPOS 2012;16;350-3. 83. Khitri MR, Mills MD, Ying GS, Davidson SL, Quinn GE. Visual acuity in pediatric glaucomas. J APPOS 2012;16:376-81. 84. Grunwald JE, Daniel E, Ying GS, Pistilli M, Maguire MG, Alexander J, Whittock-Martin R, Parker CR, Sepielli K,

Blodi BA, Martin DF, and CATT Research Group. Photographic Assessment of Fundus Morphology in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Ophthalmology 2012;119:1634-41.

85. Grunwald JE, Alexander J, Ying GS., Maguire M, Daniel E, Whittock-Martin R, Parker C, McWilliams K, Lo JC, Go A,

Townsend R, Gadegbeku CA, Lash JP, Fink JC, Rahman M, Feldman H, Kusek J, Xie D, Jaar,BG The CRIC Study Group. Retinopathy and Chronic Kidney Disease in the Chronic Renal Insufficiency Cohort (CRIC) Study. Arch.Ophthalmol. 2012;130:1136-44.

86. Dunaief DM, Fuhrman J, Dunaief JL, Ying GS. Glycemic and cardiovascular parameters improved in type 2 diabetes with the high nutrient density (HND) diet. Journal of Preventive Medicine 2012;3:364-371.

87. Ghodasa DH, Thuangtong A, Karp K, Ying GS, Mills M, Wilson CM, Fielder AR, Ng J, Quinn GE. The rate of Change in retinal vessel width and tortuosity in eyes at risk for retinopathy of prematurity. J AAPOS 2012;16:431-6.

89. Binenbaum G, Ying GS, Quinn G, Huang J, Dreiseitl S, Antigua J, Forough N, Abbasi S. The CHOP postnatal weight

gain, birth weight, and gestational age retinopathy of prematurity risk model. Archives Ophthalmology 2012;130:1560-5.

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PUBLICATIONS - Research Publications, peer reviewed (Continued): 88. Ying GS, Huang J, Maguire MG, Jaffe GJ, Grunwald JE, Cynthia T, Daniel E, Klein M, Pieramici D, Wells J, Martin

DF, and CATT Research Group. Baseline predictors for one year visual outcomes with Ranibizumab or Bevacizumab for Neovascular Age-related Macular Degeneration. Ophthalmology 2013;120:122-129.

90. Ying GS, Huang J, Maguire MG, Quinn G, Kulp MT, Ciner EB, Cyert LA, Orel-Bixler D, and Vision In Preschoolers

(VIP) Study Group. Association of anisometropia with unilateral amblyopia, interocular acuity difference and stereoacuity in preschoolers. Ophthalmology 2013;120:495-503.

91. Yaffe K, Ackerson L, Hoang TD, Go AS, Maguire MG, Ying GS, Daniel E, Bazzano LA, Coleman M, Cohen DL, Glenn

M, Kusek JW, Ojo A, Seliger S, Xie D, Gunwald GE, and CRIC Study Investigators. Retinopathy and cognitive impairment among older adults with chronic kidney disease. American Journal of Kidney Diseases 2013;61:219-27.

92. Cohen AM, Cook N, Harris MC, Ying GS, Binenbaum G. The pain response to mydriatic eye drops in preterm infants. J. Perinatol. 2013;33:462-5.

93. Hadziahmetovic M, Pajic M, Grieco S, Song Y, Li Y, Cwanger A, Iacovelli J, Chu S, Ying GS, Connelly J, Spino M, Dunaief J. The Oral iron chelator deferiprone protects against retinal degeneration induced through diverse mechanisms. Transitional vision science & technology 2012,1:2.

94. Ying GS, Heitjan DF. Prediction of Event times in the REMATCH Trial. Clinical Trials 2013;10:197-206. 95. Hagstrom S, Ying GS, Pauer GJ, et al. for the CATT Research Group. Pharmacogentics of anti-VEGF therapy in the

Comparison of AMD Treatments Trials (CATT). Ophthalmology 2013;120:593-9.

96. Brader H, Ying GS, Martin ER, Maguire MG. Characteristics of Incident Geographic Atrophy in the Complications of Age-related macular degeneration Prevention Trial. Ophthalmology 2013; 120;1871-9.

97. Jaffe GJ, Maguire MG, Cynthia T, Grunwald JE, Daniel E, Ying GS, Huang J, Martin DF and CATT Research Group. Association of Macular Morphology with Visual Acuity in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Ophthalmology 2013; 120:1860-70.

98. Zhang HY, Wang JY, Ying GS, Shen LP, Zhang Z. Serum lipids and other risk factors for diabetic retinopathy in Chinese type 2 diabetic patients. Journal of Zhejiang University Science B, 2013; 14:392-399.

99. Hankenson FC, Ruskoski N, Saun MV, Ying GS, Oh J, Fraser NW. Weight loss and reduced body temperature determine

human endpoints in a mouse model of ocular herpesvirus infection. Journal of the American Association for Laboratory Animal Science 2013; 52:277-285.

100. Huang J, Maguire MG, Ciner EB, Kulp MT, Quinn GE, Orel-Bixler D, Cyert LA, Moore B, Ying GS* (*Corresponding

Author). Inter-tester agreement in refractive error measurements. Optometry and Vision Science 2013; 90:1128-37. 101. Tamhankar MA, Biousse V, Ying GS, Prasad S, Subramanian PS, Lee MS, Eggenberger E, Moss HE, Pineles S, Bennett

J, Osborne B, Volpe NJ, Liu GT, Bruce BB, Newman NJ, Galetta SL, Balcer LJ. Isolated third, fourth and sixth cranial nerve palsies from presumed microvascular versus other causes: A prospective study. Ophthalmology 2013; 120:2264-9.

102. Pascual M, Huang J, Maguire MG, Kulp MT, Quinn GE, Ciner EB, Cyert LA, Orel-Bixler D, Moore B, Ying GS*

(*Corresponding Author). Risk factors for amblyopia in the Vision In Preschoolers Study. Ophthalmology 2014;121:622-9.

103.Ying GS, Maguire MG, Cyert L, Ciner EB, Quinn GE, Kulp MT, Orel-Bixler D, Moore B. Prevalence of vision

disorders by racial and ethnic group among children participating in Head Start. Ophthalmology 2014; 121:630-6.

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PUBLICATIONS - Research Publications, peer reviewed (Continued): 104. Grunwald JE, Daniel E, Huang J, Ying GS, Maguire MG, Toth CA, Jaffe GJ, Fine SL, Boldi B, Klein ML, Martin AA,

Hagstrom SA, Martin DF, and CATT Research Group. Risk of geographic atrophy in the Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology 2014;121:150-161.

105. Binebaum G, Christian CW, Ichord RN, Ying GS, Simon MA, Romero K, Pollock AN, Forbes BJ. Retinal hemorrhage

and brain injury patterns on diffusion-weighted magnetic resonance imaging in children with head trauma. J AAPOS 2013, 17:603-8.

106. Daniel E, Toth CA, Grunwald JE, Jaffe GJ, Martin DF, Fine SL, Huang J, Ying GS, Hagstrom SA, Winter K, Maguire

MG. Risk of scar in the Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology 2014; 121:656-66.

107. Ciner EB, Ying GS, Maguire MG, Kulp MT, Quinn GE, Cyert LA, Orel-Bixler D, Moore B, Huang J, and Vision in

Preschoolers Study Group. Stereoacuity of preschoolers with and without vision disorders. Optom Vis Sci. 2014, 91:351-8.

108. Hagstrom S, Ying GS, Pauer GJ, et al. for the CATT Research Group. VEGF-A and VEGFR-2 gene polymorphisms and

response to anti-VEGF therapy in the Comparison of AMD Treatments Trials (CATT). JAMA Ophthalmology 2014;132:521-7.

109. Ying GS, Kim BJ, Maguire MG, Huang J, Daniel E, Jaffe GL, Grunwald JE, Blinder KJ, Flaxel CJ, Rahhal F, Regillo C,

Martin DF. Sustained visual acuity loss in the in the Comparison of AMD Treatments Trials (CATT). JAMA Ophthalmology 2014;132:915-21.

110. Shah DN, Huang J, Ying GS, Pietrobon R, O’Brien JM. Trends in female representation in published ophthalmology

literature, 2000-2009. Digit J Ophthalmol. 2013;19:50-5. 111. Kulp MT, Ying GS, Huang J, Maguire MG, Quinn GE, Ciner EB, Cyert LA, Orel-Bixler D, Moore B, Accuracy of

noncycloplegic retinoscopy, Retinomax Autorefractor and SureSight Vision Screener for detecting significant refractive errors. Invest Ophthalmol Vis Sci. 2014, 55:1378-85.

112. Kulp MT, Ying GS, Huang J, Maguire MG, Quinn GE, Ciner EB, Cyert LA, Orel-Bixler D, Moore B. Association

between hyperopia and other vision and refractive error characteristics. Optom Vis Sci. 2014, 91:383-9. 112. Huang J, Ciner EB, Maguire MG, Kulp MT, Quinn GE, Cyert LA, Orel-Bixler D, Moore B, , Ying GS* (*Corresponding

Author). Risk factors of astigmatism in the Vision in Preschoolers (VIP). Optom Vis Sci. 2014, 91:514-21. 113. Kim BJ, Ying GS, Huang J, Levy NE, Maguire MG, and CATT Research Group. Sporadic visual acuity loss in the

comparison of age-related macular degeneration treatments trials (CATT). Am J Ophthalmol 2014;158:128-135. 114. Hagstrom S, Ying GS, Maguire MG, Martin D. Pharmacogenetics for genes associated with age-related macular

degeneration in the Comparison of AMD Treatments Trials (CATT). Authors reply. Ophthalmology 2014;121:e44-5.

115. Hagstrom S, Ying GS, Pauer GJ, Huang J, Maguire MG, Martin DF. Endothelial PAS domain-containing protein 1 (EPAS1) gene polymorphisms and response to anti-VEGF therapy in the Comparison of AMD Treatments Trials (CATT). Ophthalmology 2014;121:1663-1664.

116. Zhang H, Wang J, Ying GS, Shen L, Zhang Z. Diabetic retinopathy and renal function in Chinese type 2 diabetic patients. Int. Urol Nephrol. 2014;46:1375-81.

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PUBLICATIONS - Research Publications, peer reviewed (Continued): 117. Grunwald JWE, Pistilli M, Ying GS, Daniel E, Maguire MG, Xie D, Whittock-Martin R, Parker Ostroff C, Lo

JC, Townsend RR, Gadegbeku CA, Lash JP, Fink JC, Rahman M, Feldman HI, Kusek JW. The Chronic Renal Insufficiency Cohort Study Investigators. Retinopathy and progression of CKD: The Chronic Insufficiency Cohort Study. Clin J Am Soc. Nephrol. 2014;9:1217-24.

118. Folgar FA, Jaffe GJ, Ying GS, Maguire MG, Toth CA, and Comparison of Age-related Macular Degeneration.

Treatments Trials Research Group. Comparison of Optical Coherence Tomography Assessments in the Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology. 2014;121:1956-65.

119. Quinn GE, Ying GS, Daniel E, Hildebrand PL, Ells A, Baumritter A, Kemper AR, Schron EB, Wade K. Validity of a telemedicine system for the evaluation of acute-phase retinopathy of prematurity. JAMA Ophthalmology 2014;132:1178-84. 120. Lee JY, Folgar FA, Maguire MG, Ying GS, Toth CA, Martin DF, Jaffe GJ, and CATT Research Group.

Outer retinal tabulation in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Ophthalmology 2014;121:2423-31.

121. Doty RL, Beals E, Osman A, Dubroff J, Chung I, Leon-Samiento FE, Hurtig H, Ying GS. Suprathreshold odor

intensity perception in early-stage Parkinson’s disease. Mov Disord. 2014;29:1208-12. 122. Gewaily DY, Grunwald JE, Pistilli M, Ying GS, Maguire MG, Daniel E, Ostroff CP, Fine SL and CATT

Research Group. Delayed patchy choroidal filling in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Am J Ophthalmol. 2014;158:525-31.

123. Rayess N, Rahimy E, Ying GS, Bagheri N, Ho AC, Regillo CD, Vander JF, Hsu J. Baseline choroidal thickness as a

predictor for response to anti-vascular endothelial growth factor therapy in diabetic macular edema. Am J Ophthalmol. 2015; 159:85-91.

124. Aleman TS, Huang J, Garrity ST, Carter ST, Aleman WD, Ying GS, Tamhankar MA. Relationship between

optic nerve appearance and retinal nerve fiber layer thickness as explored with spectral domain optical coherence tomography. Transl Vis Sci Technol. 2014;3:4.

125. Doty RL, Gandhi SS, Osman A, Hurtig HI, Pawasarat I, Beals E, Chung I, Dubroff J, Newberg A, Ying GS,

Leon-Sarmiento FE. Point pressure sensitivity in early stage Parkinson's disease. Physiol Behav. 2014;138:21-7. 126. Kemper AR, Wade KC, Hornik CP, Ying GS, Baumritter A, Quinn GE; Telemedicine Approaches to

Evaluating Acute-phase Retinopathy of Prematurity (e-ROP) Study Cooperative Group. Retinopathy of Prematurity Risk Prediction for Infants with Birth Weight Less than 1251 Grams. J Pediatr. 2015;166:257-61.

127. Doty RL, Nsoesie MT, Chung I, Osman A, Pawasarat I, Caulfield J, Hurtig H, Silas J, Dubroff J, Duda JE,

Ying GS, Tekeli H, Leon-Sarmiento FE. Taste function in early stage treated and untreated Parkinson's disease. J Neurol. 2015;262:547-57.

128. Ying GS, Quinn GE, Wade KC, Repka MX, Baumritter A, Daniel E. Predictors for the development of

referral-warranted retinopathy of prematurity in the telemedicine approaches to evaluating acute-phase retinopathy of prematurity (e-ROP) Study. JAMA Ophthalmol 2015;133:304-11.

129. Charlson ES, Sankar PS, Miller-Ellis E, Regina M, Fertig R, Salinas J, Pistilli M, Salowe RJ, Rhodes AL,

Merritt WT 3rd, Chua M, Trachtman BT, Gudiseva HV, Collins DW, Cavali VR, Nichols C, Henderer J, Ying GS, Varma R, Jorgenson E, O’Brien JM. The primary open-angle African American Glaucoma Genetics Study: Baseline Demographics. Ophthalmology 2015;122:711-20.

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PUBLICATIONS - Research Publications, peer reviewed (Continued): 130. Grunwald JE, Pistilli M, Ying GS, Maguire MG, Daniel E, Martin DF, and Comparison of Age-related

Macular Degeneration Treatments Trials Research Group. Growth of geographic atrophy in the comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology 2015, 122:809-16.

131. Abbasian J, Blair N, Shahidi M, Ying GS, Huang J, Kaufman L, Blair M. Macular optical coherence

tomography in patients with unilateral optic nerve hypoplasia. J AAPOS 2015;57-61. 132. Hunter AA 3rd, Smit-McBride Z, Anderson R, Bordbari MH, Ying GS, Kim ES, Park SS, Telander DG,

Dunaief JL, Hjelmeland LM, Morse LS. Curr Eye Res. 2015; 21:1-7. 133. Chavali VR, Diniz B, Huang J, Ying GS, Sadda SR, Stambolian D. Association of OCT derived drusen

measurements with AMD associated-genotypic SNPs in Amish population. J Clin Med 2015;4:304-317. 135. Cuilla TA, Ying GS, Maguire MG, Martin DF, Gaffe GJ, Grunwald JE, Daniel E, Toth CA, and Comparison of Age-related Macular Degeneration Treatments Trials Research Group. Influence of vietromacular interface

on treatment outcomes in the Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology 2015;122:1203-11.

136. Bunya VY, Fuerst BM, Pistilli M, McCabe BE, Salvo R, Macchi I, Ying GS, Massaro-Giordano M. Variability of tear osmolarity in patients with dry eye. JAMA Ophthamol 2015; 133:662-7. 137. Daniel E, Quinn GE, Hildebrand PL, Ells A, Hubbard GB 3rd, Capone A Jr, Martin ER, Ostroff CP, Smith E,

Pistilli M, Ying GS. And e-ROP Cooperative Group. Validated System for Centralized Grading of Retinopathy of Prematurity: Telemedicine Approaches to Evaluating Acute-Phase Retinopathy of Prematurity (e-ROP) Study. JAMA Ophthamol 2015;133:675-82.

138. Mehta R, Ying GS, Houston S, Isakova T, Nessel L, Ojo A, Go A, Lash J, Kusek J, Grunwald J, Wolf M; CRIC Study Investigators. Phosphate, fibroblast growth factor 23 and retinopathy in chronic kidney disease: the Chronic Renal Insufficiency Cohort Study. Nephrol Dial Transplant. 2015;30:1534-41.

139. Hagstrom SA, Ying GS, Maguire MG, Martin DF; CATT Research Group, Gibson J, Lotery A, Chakravarthy U; IVAN Study Investigators. VEGFR2 Gene Polymorphisms and Response to Anti-Vascular Endothelial Growth Factor Therapy in Age-Related Macular Degeneration. Ophthalmology 2015,122:1563-8.

140. Toth CA, Decroos FC, Ying GS, Stinnett SS, Heydary CS, Burns R, Maguire M, Martin D, Jaffe GJ.

Identification of fluid on optical coherence tomography by treating ophthalmologists versus a reading center in the comparison of age-related macular degeneration treatments trials. Retina 2015;35:1303-14.

141. Willoughby AS, Ying GS, Toth CA, Maguire MG, Burns RE, Grunwald JE, Daniel E, Jaffe GJ;

Comparison of Age-Related Macular Degeneration Treatments Trials Research Group. Subretinal Hyperreflective Material in the Comparison of Age-Related Macular Degeneration Treatments Trials.Ophthalmology. 2015;122:1846-53.

142. Heitjan DF, Ge Z, Ying GS. Real-Time Prediction of Clinical Trial Enrollment and Event Counts: A Review.

Contemp Clin Trials. 2015 45 (PtA):26-33.

143. Jensen AK, Coleman C, Stokes D, Ying GS, Huang J, Kuhn I, Binenbaum G. Filter paper-based insulin-like growth factor assay. J AAPOS 2015;19:363-5.

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PUBLICATIONS - Research Publications, peer reviewed (Continued): 144. Ying GS, Maguire MG, Daniel E, Ferris FL, Jaffe GJ, Grunwald JE, Toth C, Huang J, Martin DF,

Comparison of Age-Related Macular Degeneration Treatments Trials Research Group. Association of baseline characteristics and early vision response with two-year vision outcomes in the Comparison of AMD Treatments Trials (CATT). Ophthalmology 2015; 122:2523-31.

145. Binenbaum G, Christian CW, Guttmann K, Huang J, Ying GS, Forbes BJ. Evaluation of Temporal

Association Between Vaccinations and Retinal Hemorrhage in Children. JAMA Ophthalmol. 2015;144:1261-5.

146. Geloneck MM, Forbes BJ, Shaffer J, Ying GS, Binenbaum G. Ocular Complications in Children with Diabetes Mellitus. Ophthalmology. 2015;122:2457-64.

147. Wade KC, Pistilli M, Baumritter A, Karp K, Gong A, Kemper AR, Ying GS, Quinn G; e-Retinopathy of

Prematurity Study Cooperative Group. Safety of Retinopathy of Prematurity Examination and Imaging in Premature Infants. J Pediatr. 2015;167:994-1000.

148. Grunwald JE, Pistilli M, Ying GS, Maguire M, Daniel E, Whittock-Martin R, Parker-Ostroff C, Mohler E, Lo JC,

Townsend RR, Gadegbeku CA, Lash JP, Fink JC, Rahman M, Feldman H, Kusek JW, Xie D; CRIC Study Investigators. Retinopathy and the risk of cardiovascular disease in patients with chronic kidney disease (from the Chronic Renal Insufficiency Cohort study). A J Cadiol 2015;116(10):1527-33.

149. Beltran WA, Cideciyan AV, Iwabe S, Swider M, Kosyk MS, McDaid K, Martynyuk I, Ying GS, Shaffer J, Deng

WT, Doyer SL, Lewin AS, Hauswirth WW, Jacobson SG, Aguirre GD. Successful arrest of photoreceptor and vision loss expands the therapeutic window of retinal gene therapy to laster stages of disease. Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):E5844-53. doi: 10.1073/pnas.1509914112. Epub 2015 Oct 12. PubMed PMID: 26460017; PubMed Central PMCID: PMC4629324.

150. Ying GS, Maguire MG, Daniel E, Grunwald J, Ahmed O, Martin DF, and Comparison of Age-Related Macular

Degeneration Treatments Trials Research Group. Association between antiplatelet or anticoagulant drugs and retinal/subretinal hemorrhage in the Comparison of AMD Treatments Trials (CATT). Ophthalmology 2016 Feb;123(2):352-60. doi: 10.1016/j.ophtha.2015.09.046. Epub 2015 Nov 4. PubMed PMID: 26545320; PubMed Central PMCID: PMC4724480.

151. Shah N, Maguire MG, Martin DF, Shaffer J, Ying GS, Grunwald JE, Toth CA, Jaffe GJ, Daniel E;

Comparison of Age-related Macular Degeneration Treatments Trials Research Group. Angiographic Cystoid Macular Edema and Outcomes in the Comparison of Age-Related Macular Degeneration Treatments Trials. Ophthalmology. 2016 Apr;123(4):858-64. PubMed Central PMCID: PMC4808340.

152. Daniel E, Shaffer J, Ying GS, Grunwald JE, Martin DF, Jaffe GJ, Maguire MG; Comparison of Age- Related Macular Degeneration Treatments Trials (CATT) Research Group. Outcomes in Eyes with Retinal Angiomatous Proliferation in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT). Ophthalmology. 2016 Mar;123(3):609-16.PubMed Central PMCID: PMC4766028.

153. Kemper AR, Prosser LA, Wade KC, Repka MX, Ying GS, Baumritter A, Quinn GE; e-ROP Study Cooperative Group. A Comparison of Strategies for Retinopathy of Prematurity Detection. Pediatrics. 2016;137(1):1-10. 2016 Jan;137(1). doi: 10.1542/peds.2015-2256. Epub 2015 Dec 15. PubMed PMID: 26672022; PubMed Central PMCID: PMC4702020.

154. Sharma S, Toth CA, Daniel E, Grunwald JE, Maguire MG, Ying GS, Huang J, Martin DF, Jaffe GJ; Comparison of Age-related Macular Degeneration Treatments Trials Research Group. Macular Morphology and Visual Acuity in the Second Year of the Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology 2016 Apr;123(4):865-75.

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PUBLICATIONS - Research Publications, peer reviewed (Continued):

155. Salowe RJ, Sankar P, Miller-Ellis E, Pistilli M, Ying GS, O'Brien JM. The role of ophthalmology departments in overcoming health care disparities. J Epidemiol Res. 2016;2(1):25-28. PubMed PMID: 26819970; PubMed Central PMCID: PMC4724872.

156. Kulp MT, Ciner E, Maguire M, Moore B, Pentimonti J, Pistilli M, Cyert L, Candy TR, Quinn G, Ying GS. Uncorrected Hyperopia and Preschool Early Literacy: Results of the Vision in Preschoolers- Hyperopia in Preschoolers (VIP-HIP) Study. Ophthalmology. 2016 Apr;123(4):681-9. PubMed PMID: 26826748; PubMed Central PMCID: PMC4808323.

157. Zhou Q, Shaffer J, Ying GS. Pseudodrusen in the Fellow Eye of Patients with Unilateral Neovascular Age-Related Macular Degeneration: A Meta-Analysis. PLoS One. 2016 Feb 19;11(2):e0149030. doi: 10.1371/journal.pone.0149030. eCollection 2016. PubMed PMID: 26895455; PubMed Central PMCID: PMC4760707.

158. Durrani K, Kempen JH, Ying GS, Kacmaz RO, Artornsombudh P, Rosenbaum JT, Suhler EB, Thorne JE,

Jabs DA, Levy-Clarke GA, Nussenblatt RB, Foster CS, Site Research Group. Adalimumab for Ocular Inflammation. Ocul Immunol Inflamm. 2016 Mar 22:1-8. PubMed PMID: 27003323.

159. Zhou Q, Daniel E, Maguire MG, Grunwald JE, Martin ER, Martin DF, Ying GS; Comparison of Age-

Related Macular Degeneration Treatments Trials Research Group. Pseudodrusen and Incidence of Late Age-Related Macular Degeneration in Fellow Eyes in the Comparison of Age-Related Macular Degeneration Treatments Trials. Ophthalmology. 2016 Jul;123(7):1530-40.

160. Binenbaum G, Chen W, Huang J, Ying GS, Forbes BJ. The natural history of retinal hemorrhage in pediatric head trauma. J AAPOS. 2016 Apr;20(2):131-5. doi: 10.1016/j.jaapos.2015.12.008. PubMed PMID: 27079593; PubMed Central PMCID: PMC4839593.

161. Quinn GE, Barr C, Bremer D, Fellows R, Gong A, Hoffman R, Repka MX, Shepard J, Siatkowski RM,

Wade K, Ying GS. Changes in Course of Retinopathy of Prematurity from 1986 to 2013: Comparison of Three Studies in the United States. Ophthalmology. 2016 Jul;123(7):1595-600. doi:

10.1016/j.ophtha.2016.03.026. Epub 2016 Apr 12. PubMed PMID: 27084562; PubMed Central PMCID: PMC4921295.

162. Iwabe S, Ying GS, Aguirre GD, Beltran WA. Assessment of visual function and retinal structure following acute light exposure in the light sensitive T4R rhodopsin mutant dog. Exp Eye Res. 2016 May;146:341-53. doi:10.1016/j.exer.2016.04.006. Epub 2016 Apr 13. PubMed PMID: 27085210.

163. Maguire MG, Ying GS, Jaffe GJ, Toth CA, Daniel E, Grunwald J, Martin DF, Hagstrom SA; CATT

Research Group. Single-Nucleotide Polymorphisms Associated With Age-Related Macular Degeneration and Lesion Phenotypes in the Comparison of Age-Related Macular Degeneration Treatments Trials. JAMA Ophthalmol. 2016 Jun 1;134(6):674-81. doi: 10.1001/jamaophthalmol.2016.0669. PubMed PMID: 27099955.

164. Maguire MG, Martin DF, Ying GS, Jaffe GJ, Daniel E, Grunwald JE, Toth CA, Ferris FL 3rd, Fine SL for the Comparison of Age-related Macular Degeneration Treatments Trials (CATT) Research Group. Five-Year Outcomes with Anti-Vascular Endothelial Growth Factor Treatment of Neovascular Age- Related Macular Degeneration: The Comparison of Age-Related Macular Degeneration Treatments Trials. Ophthalmology. 2016 Apr 20. pii: S0161-6420(16)30092-6. doi: 10.1016/j.ophtha.2016.03.045.

[Epub ahead of print] PubMed PMID: 27156698.

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PUBLICATIONS - Research Publications, peer reviewed (Continued): 165. Karp KA, Baumritter A, Pearson DJ, Pistilli M, Nyquist D, Huynh M, Satnes K, Keith R, Ying GS,

Quinn GE; e-ROP Cooperative Group. Training retinal imagers for retinopathy of prematurity (ROP) screening. J AAPOS. 2016 Jun;20(3):214-9. doi: 10.1016/j.jaapos.2016.01.016. Epub 2016 May 6. PubMed PMID: 27164425; PubMed Central PMCID: PMC4936410.

166. Rahimy E, Shahlaee A, Khan MA, Ying GS, Maguire JI, Ho AC, Regillo CD, Hsu J. Conversion to Aflibercept After Prior Anti-VEGF Therapy for Persistent Diabetic Macular Edema. Am J Ophthalmol. 2016;164:118-27. PubMed PMID: 27270363.

167. Milman T, Ying GS, Pan W, LiVolsi V. Ameloblastoma: 25 Year Experience at a Single Institution. Head

Neck Pathol. 2016;10:513-520. PubMed PMID: 27272180. 168. Pleet A, Sulewski M, Salowe RJ, Fertig R, Salinas J, Rhodes A, Merritt Iii W, Natesh V, Huang J, Gudiseva HV, Collins DW, Chavali VR, Tapino P, Lehman A, Regina-Gigiliotti M, Miller-Ellis E, Sankar P, Ying GS, O'Brien JM. Risk Factors Associated with Progression to Blindness from Primary Open-Angle Glaucoma in an African-American Population. Ophthalmic Epidemiol. 2016 Aug;23(4): 248-56. doi: 10.1080/09286586.2016.1193207. Epub 2016 Jun 27. PubMed PMID: 27348239; PubMed Central PMCID: PMC4939437. 169. Ying GS, VanderVeen D, Daniel E, Quinn GE, Baumritter A, and e-ROP Research Group. Risk score for

predicting treatment-requiring retinopathy of prematurity (ROP) in the telemedicine approaches to evaluating acute-pahse ROP Study. Ophthalmology 2016;123:2176-82. PMCID: PMC5035617.

170. Grunwald JE, Pistilli M, Daniel E, Ying GS, Pan W, Jaffe GJ, Toth CA, Hagstrom SA, Maguire MG, Martin DF; Comparison of Age-Related Macular Degeneration Treatments Trials Research Group. Incidence and Growth of Geographic Atrophy during 5 Years of Comparison of Age-Related Macular Degeneration Treatments Trials. Ophthalmology. 2017 Jan;124(1):97-104.

171. Quinn GE, Ying GS, Repka MX, Siatkowski RM, Hoffman R, Mills MD, Morrison D, Daniel E, Baumritter A,

Hildebrand PL, Schron EB, Ells AL, Wade K, Kemper AR. Timely implementation of a retinopathy of prematurity telemedicine system. J AAPOS. 2016 Oct;20(5):425-430.e1.

172. Morrison D, Bothun ED, Ying GS, Daniel E, Baumritter A, Quinn G; e-ROP Cooperative Group..Impact of

number and quality of retinal images in a telemedicine screening program for ROP: results from the e-ROP study. J AAPOS. 2016 Dec;20(6):481-485.

173. Quinn GE, Ells A, Capone A Jr, Hubbard GB, Daniel E, Hildebrand PL, Ying GS; e-ROP (Telemedicine

Approaches to Evaluating Acute-Phase Retinopathy of Prematurity) Cooperative Group. Analysis of Discrepancy Between Diagnostic Clinical Examination Findings and Corresponding Evaluation of Digital Images in the Telemedicine Approaches to Evaluating Acute-Phase Retinopathy of Prematurity Study. JAMA Ophthalmol. 2016 Nov 1;134(11):1263-1270. doi: 10.1001/jamaophthalmol.2016.3502.

174. Rayess N, Rahimy E, Ying GS, Pefkianaki M, Franklin J, Regillo CD, Ho AC, Hsu J. Baseline Choroidal

Thickness as a Predictor for Treatment Outcomes in Central Retinal Vein Occlusion. Am J Ophthalmol. 2016 Nov;171:47-52. doi: 10.1016/j.ajo.2016.08.026.

175. Jensen AK, Ying GS, Huang J, Quinn GE, Binenbaum G. Postnatal serum insulin-like growth factor I and

retinopathy of prematurity. Retina. 2017;37:867-872.

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PUBLICATIONS - Research Publications, peer reviewed (Continued):

176. Aleman TS, Han G, Serrano LW, Fuerst NM, Charlson ES, Pearson DJ, Chung DC, Traband A, Pan W, Ying GS, Bennett J, Maguire AM, Morgan JI. Natural History of the Central Structural Abnormalities in Choroideremia: A Prospective Cross-Sectional Study. Ophthalmology. 2017 Mar;124(3):359-373. doi: 10.1016/j.ophtha.2016.10.022.

177. Daniel E, Ying GS, Siatkowski RM, Pan W, Smith E, Quinn GE; e-ROP Cooperative Group.. Intraocular Hemorrhages and Retinopathy of Prematurity in the Telemedicine Approaches to Evaluating Acute-Phase Retinopathy of Prematurity (e-ROP) Study. Ophthalmology. 2017 Mar;124(3):374-381. doi: 10.1016/j.ophtha.2016.10.040.

178. Ferris FL 3rd, Maguire MG, Glassman AR, Ying GS, Martin DF. Evaluating Effects of Switching Anti-Vascular Endothelial Growth Factor Drugs for Age-Related Macular Degeneration and Diabetic Macular Edema. JAMA Ophthalmol. 2016 Dec 22. doi: 10.1001/jamaophthalmol.2016.4820. [Epub ahead of print]

179. Gurwin J, Tomlinson LA, Quinn GE, Ying GS, Baumritter A, Binenbaum G; Postnatal Growth and Retinopathy of Prematurity (G-ROP) Study Group and the Telemedicine Approaches to Evaluating Acute-Phase Retinopathy of Prematurity (e-ROP) Cooperative Group.. A Tiered Approach to Retinopathy of Prematurity Screening (TARP) Using a Weight Gain Predictive Model and a Telemedicine System. JAMA Ophthalmol. 2017 Jan 5. doi: 10.1001/jamaophthalmol.2016.5203. [Epub ahead of print]

180. Grunwald JE, Pistilli M, Daniel E, Ying GS, Pan W, Jaffe GJ, Toth CA, Hagstrom SA, Maguire MG, Martin DF; Comparison of Age-Related Macular Degeneration Treatments Trials Research Group. Incidence and Growth of Geographic Atrophy during 5 Years of Comparison of Age-Related Macular Degeneration Treatments Trials. Ophthalmology. 2017 Jan;124(1):97-104. doi: 10.1016/j.ophtha.2016.09.012.

181. Ying GS, Maguire MG, Glynn R, Rosner B. Tutorial on Biostatistics: Linear Regression Analysis of Continuous Correlated Eye Data. Ophthalmic Epidemiol. 2017;24:130-140.

182. Rayess N, Ying GS, Pefkianaki M, Franklin J, Regillo CD, Ho AC, Hsu J, Rahimy E. Baseline Choroidal Thickness as a Predictor for Treatment Outcomes in Central Retinal Vein Occlusion. Am J Ophthalmol. 2017 Feb 9. pii: S0002-9394(17)30045-4. doi: 10.1016/j.ajo.2017.01.022. [Epub ahead of print] No abstract available.

183. Ashtari M, Nikonova ES, Marshall KA, Young GJ, Aravand P, Pan W, Ying GS, Willett AE, Mahmoudian M, Maguire AM, Bennett J. The Role of the Human Visual Cortex in Assessment of the Long-Term Durability of Retinal Gene Therapy in Follow-on RPE65 Clinical Trial Patients. Ophthalmology. 2017;124:873-883. doi: 10.1016/j.ophtha.2017.01.029.

184. Swanson JW, Aleman TS, Xu W, Ying GS, Pan W, Liu GT, Lang SS, Heuer GG, Storm PB, Bartlett SP, Katowitz WR, Taylor JA. Evaluation of Optical Coherence Tomography to Detect Elevated Intracranial Pressure in Children. JAMA Ophthalmol. 2017;135:320-328. doi: 10.1001/jamaophthalmol.2017.0025.

185. Rogers DL, Bremer DL, Fellows RR, Baumritter A, Daniel E, Pastilli M, Ying GS, Quinn GE; e-ROP Cooperative Group.. Comparison of strategies for grading retinal images of premature infants for referral warranted retinopathy of prematurity. J AAPOS. 2017 Apr;21(2):141-145. doi: 10.1016/j.jaapos.2017.01.001. Epub 2017 Mar 20.

186. Zhou Q, Daniel E, Grunwald JE, Maguire MG, Gewaily DY, Martin DF, Ying GS (corresponding author) CATT Research Group. Association between pseudodrusen and delayed patchy choroidal filling in the comparison of age-related macular degeneration treatments trials. Acta Ophthalmol. 2017;95:e518-e520. doi: 10.1111/aos.13398. [Epub ahead of print].

187. Ying GS, Maguire MG, Kulp MT, Ciner E, Moore B, Pistilli M, Candy R; VIP-HIP Study Group. Comparison of cycloplegic refraction between Grand Seiko autorefractor and Retinomax autorefractor in the Vision in Preschoolers-Hyperopia in Preschoolers (VIP-HIP) Study. J AAPOS. 2017 Jun;21(3):219-223.

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PUBLICATIONS - Research Publications, peer reviewed (Continued):

188. Govorkova MS, Milman T, Ying GS, Pan W, Silkiss RZ. Inflammatory Mediators in Xanthelasma Palpebrarum: Histopathologic and Immunohistochemical Study. Ophthal Plast Reconstr Surg. 2017 May 5. Ophthalmic Plast Reconstr Surg. 2018 May/Jun;34(3):225-230.

189. Ying GS, Maguire MG, Glynn R, Rosner B. Tutorial on Biostatistics: Statistical Analysis for Correlated Binary Eye Data. Ophthalmic Epidemiol. 2018;25(1):1-12.

190. Ying GS, Zhang Q, Lan Y, Li Y, Heitjan DF. Cure modeling in real-time prediction: How much does it help? Contemp Clin Trials 2017;59:30-37.

191. Beltran WA, Cideciyan AV, Boye SE, Ye GJ, Iwabe S, Dufour VL, Marinho LF, Swider M, Kosyk MS, Sha J, Boye SL, Peterson JJ, Witherspoon CD, Alexander JJ, Ying GS, Shearman MS, Chulay JD, Hauswirth WW, Gamlin PD, Jacobson SG, Aguirre GD. Optimization of Retinal Gene Therapy for X-Linked Retinitis Pigmentosa Due to RPGR Mutations. Mol Ther. 2017 Aug 2;25(8):1866-1880. doi: 10.1016/j.ymthe.2017.05.004. Epub 2017 May 27.

192. Daniel E, Grunwald JE, Kim BJ, Maguire MG, Jaffe GJ, Toth CA, Ferris FL 3rd, Martin DF, Shaffer J, Ying GS; Comparison of Age-related Macular Degeneration Treatments Trials (CATT) Research Group. Visual and Morphologic Outcomes in Eyes with Hard Exudate in the Comparison of Age-Related Macular Degeneration Treatments Trials. Ophthalmol Retina. 2017 Jan-Feb;1(1):25-33. doi: 10.1016/j.oret.2016.09.001. PMID:28620652

193. Doroslovački P, Tamhankar MA, Liu GT, Shindler KS, Ying GS, Alonso-Basanta M. Factors Associated with Occurrence of Radiation-induced Optic Neuropathy at "Safe" Radiation Dosage. Semin Ophthalmol. 2017 Jul 13:1-8. doi: 10.1080/08820538.2017.1346133. [Epub ahead of print]

194. Binenbaum G, Ying GS, Tomlinson LA; Postnatal Growth and Retinopathy of Prematurity (G-ROP) Study Group. Validation of the Children's Hospital of Philadelphia Retinopathy of Prematurity (CHOP ROP) Model. JAMA Ophthalmol. 2017 Aug 1;135(8):871-877.

195. Quinn GE, Ying GS, Pan W, Baumritter A, Daniel E; Telemedicine Approaches to Evaluating Acute-Phase Retinopathy of Prematurity Cooperative Group. Detection of Potentially Severe Retinopathy of Prematurity by Remote Image Grading. JAMA Ophthalmol. 2017;135(9):982-986.

196. Kim BJ, Irwin DJ, Song D, Daniel E, Leveque JD, Raquib AR, Pan W, Ying GS,Aleman TS, Dunaief JL, Grossman M. Optical coherence tomography identifies outer retina thinning in frontotemporal degeneration. Neurology 2017;89(15):1604-1611.

197. Huang J, Huang J, Chen Y, Ying GS*. Evaluation of approaches to analyzing continuous correlated data when sample size is small. Ophthalmic Epidemiol. 2017 Sep 11:1-10.

198. Kulp MT, Ciner E, Maguire Pistilli M, Candy TR, Ying GS, Quinn G, Cyert L, Moore B; Vision in Preschoolers-Hyperopia in Preschoolers Study Group. Attention and Visual Motor Integration in Young Children with Uncorrected Hyperopia. Optom Vis Sci. 2017 Oct;94(10):965-970.

199. Ying GS, Pan W, Quinn GE, Daniel E, Repka MX, Baumritter A. Intereye Agreement of Retinopathy of Prematurity from Image Evaluation in the Telemedicine Approaches to Evaluating of Acute-Phase ROP (e-ROP) Study. Ophthalmol Retina. 2017 Jul-Aug;1(4):347-354.

200. Mehta S, Ying GS, Hussain A, Harvey JT. Is gastroesophageal reflux disease associated with primary acquired nasolacrimal duct obstruction? Orbit 2017, Oct 17:1-5.

201. Bunya VY, Fernandez KB, Ying GS, Massaro-Giordano M, Macchi I, Sulewski ME, Hammersmith KM, Nagra PK, Rapuano CJ, Orlin SE. Survey of Ophthalmologists Regarding Practice Patterns for Dry Eye and Sjogren Syndrome. Eye Contact Lens. 2018 Jan 15.. [Epub ahead of print]

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PUBLICATIONS - Research Publications, peer reviewed (Continued):

202. Daniel E, Pan W, Quinn GE, Smith E, Baumritter A, Ying GS; Telemedicine Approaches to Evaluating Acute-Phase Retinopathy of Prematurity (e-ROP) Cooperative Group. Single grading vs double grading with adjudication in the telemedicine approaches to evaluating acute-phase retinopathy of prematurity (e-ROP) study. J AAPOS. 2018;22:32-37 .

203. Zhang HG, Ying GS. Statistical approaches in published ophthalmic clinical science papers: a comparison to statistical practice two decades ago. Br J Ophthalmol 2018 [Epub ahead of print].

204. Daniel E, Pan W, Ying GS, Kim BJ, Grunwald JE, Ferris FL 3rd, Jaffe GJ, Toth CA, Martin DF, Fine SL, Maguire MG. Development and course of scars in the Comparison of Age-related macular degeneration treatment trials. Ophthalmology 2018 [Epub ahead of print].

205. Rahimy E, Ying GS, Pan W, Hsu J. Effect of intraocular pressure-lowering medications on neovascular age-related macular degeneration treatment outcomes in the Comparison of Age-related Macular Degeneration Treatment Trials. Retina 2018 [Epub ahead of print].

206. McCourt EA, Ying GS, Lynch AM, Palestine AG, Wagner BD, Wymore E, Tomlinson LA, Binenbaum G. Validation of the Colorado Retinopathy of Prematurity Screening Model. JAMA Ophthalmol 2018 [Epub ahead of print].

207. Morrison D, Shaffer J, Ying GS, Binenbaum G. Ocular complications following treatment in the Postnatal Growth and Retinopathy of Prematurity. J AAPOS 2018 [Epub ahead of print].

208. O’Brien JM, Salowe JR, Fertig R, Salinas J, Pistilli M, Sankar PS, Miller-Ellis E, Lehman A, Murphy W, Homsher M, Gordon K, Ying GS. Family history in Primary Open-angle African American Glaucoma Genetics Study Cohort. Am J Ophthalmol. 2018 [Epub ahead of print].

209. Song JY, Aravand P, Nikonov S, Leo L, Lyubarsky A, Bennicelli JL, Pan J, Wei Z, Shpylchak I, Herrera P, Bennett DJ, Commins N, Maguire AM, Pham J, den Hollander AI, Cremers FPM, Koenekoop RK, Roepman R, Nishina P, Zhou S, Pan W, Ying GS, Aleman TS, de Melo J, McNamara I, Sun J, Mills J, Bennett J. Amelioration of neurosensory structure and function in anumals and cellular models of a Congenital blindness. Mol Ther. 2018 [Epub ahead of print].

210. O'Neil EC, Huang J, Suhler EB, Dunn JP Jr, Perez VL, Gritz DC, McWilliams K, Peskin E, Ying GS, Bunya VY, Maguire MG, Kempen JH. Iontophoretic delivery of dexamethasone phosphate for non-infectious, non-necrotising anterior scleritis, dose-finding clinical trial. Br J Ophthalmol. 2018 [Epub ahead of print].

211. Rayess N, Rahimy E, Ying GS, Pefkianaki M, Franklin J, Regillo CD, Ho AC, Hsu J. Baseline choroidal thickness as a short-term predictor of visual acuity improvement following antivascular endothelial growth factor therapy in branch retinal vein occlusion. Br J Ophthalmol. 2018 [Epub ahead of print].

Contributions to peer-reviewed clinical research publications as a writing team leader or member: 1. Choroidal Neovascularization Prevention Trial Research Group (Writing team member). Laser treatment in fellow eyes

with large drusen: updated findings from a pilot randomized clinical trial. Ophthalmology 2003; 110:971-8.

2. Vision in Preschoolers (VIP) Study Group (Writing team member, Biostatistician for the Coordinating Center). Visual acuity results in school-aged children and adults: Lea Symbols chart versus Bailey-Lovie chart. Optom Vis Sci 2003; 80:650-4.

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3. Vision in Preschoolers (VIP) Study Group (Writing team member; Biostatistician for the Coordinating Center). Comparison of Preschool Vision Screening Tests as Administered by Licensed Eyecare Professionals in the Vision in Preschoolers (VIP) Study. Ophthalmology 2004; 111:637-50.

4. Complications of Age-related Macular Degeneration Prevention Trial Research Group (Writing team leader,

Biostatistician for the Coordinating Center). Baseline Characteristics, the NEI-VFQ-25, and Their Associations in the Complications of Age-Related Macular Degeneration Prevention Trial (CAPT). Ophthalmology 2004; 111:1307-16.

5. Vision in Preschoolers (VIP) Study Group (Writing team leader; Senior Biostatistician for the Coordinating Center).

Sensitivity of screening tests for detecting VIP-targeted vision disorders when specificity is 94%. Optom Vis Sci 2005; 82:432-8.

6. Vision in Preschoolers (VIP) Study Group (Writing team member; Senior Biostatistician for the Coordinating Center). Preschool vision screening tests administered by nurse screeners compared to lay screeners in the Vision in Preschoolers Study Invest Ophthalmol Vis Sci 2005; 46:2639-48.

7. Complications of Age-related Macular Degeneration Prevention Trial Research Group. (Writing team member, Senior Biostatistician for the Coordinating Center). Laser treatment in patients with bilateral large drusen - The Complications of Age-related Macular Degeneration Prevention Trial. Ophthalmology 2006; 113:1974-86. 8. Vision in Preschoolers (VIP) Study Group (Writing team leader; Senior Biostatistician for the Coordinating

Center).Impact of confidence number on the screening accuracy of the Retinomax Autorefractor. Optom Vis Sci 2007; 84:181-188.

9. Vision in Preschoolers (VIP) Study Group (Writing team member; Senior Biostatistician for the Coordinating Center).

Does Assessing eye alignment along with refractive error or visual acuity increase sensitivity for detection of strabismus in Preschool Vision Screening? Invest Ophthalmol Vis Sci. 2007; 48:3115-3125.

10. Complications of Age-related Macular Degeneration Prevention Trial Research Group. (Writing team leader, Senior

Biostatistician for the Coordinating Center). Risk factors for Choroidal Neovascularization and Geographic Atrophy in the Complications of Age-related Macular Degeneration Prevention Trial. Ophthalmology 2008; 115:1474-79.

11. Vision in Preschoolers (VIP) Study Group (Writing team member; Senior Biostatistician for the Coordinating Center).

Findings from the Vision in Preschoolers (VIP) Study. Optom Vis Sci. 2009;86:619-23. 12. Vision in Preschoolers (VIP) Study Group (Writing team member; Senior Biostatistician for the Coordinating Center).

Comparison of Retinomax and Palm-AR Auto-Refractors: A Pilot Study. Optom Vis Sci. 2011;88:830-836. 13. Vision in Preschoolers (VIP) Study Group (Writing team member; Senior Biostatistician for the Coordinating Center).

Age Comparison for Lea Symbols and HOTV in Preschool Vision Screening. Optom Vis Sci 2010:87:87-95. 14. Vision in Preschoolers (VIP) Study Group (Writing team leader; Senior Biostatistician for the Coordinating Center).

Impact of Confidence Number on the Accuracy of SureSight Vision Screener. Optom Vis Sci 2010;87:96-103. 15. Vision in Preschoolers (VIP) Study Group (Writing team member; Senior Biostatistician for the Coordinating Center).

Comparison of the Retinomax Autorefractor and Palm-automatic refractometer: a pilot study in the Vision in Preschoolers Study. Optom Vis Sci.2011;88:830-6.

16. Comparison of AMD Treatment Trials (CATT) Study Group. (One of the 6 Writing team member; Senior

Biostatistician for the Coordinating Center). Ranibizumab and Bevacizumab for Neovascular Age-related Macular Degeneration(AMD). New England Journal of Medicine 2011, 364:1897-908.

17. Comparison of AMD Treatment Trials (CATT) Study Group. (One of the 9 Writing team member; Senior

Biostatistician for the Coordinating Center). Ranibizumab and Bevacizumab for Treatment of Neovascular Age-

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related Macular Degeneration Treatments Trials (CATT). Ophthalmology 2012, 119:1388-98.

18. The Dry Eye Assessment and Management (DREAM) Study Group. (One of the 8 Writing team member; Senior

Biostatistician for the Coordinating Center). The omega-3 fatty acid supplementation for the treatment of dry eye disease. New England Journal of Medicine 2018, DOI:10.1056/NEJMoa1709691.

Contributions to peer-reviewed clinical research publications, participation cited or acknowledged but not by authorship: 1. Complications of Age-related Macular Degeneration Prevention Trial Research Group. (Ying GS as Biostatistician for the

Coordinating Center). The Complications of Age-related Macular Degeneration Prevention Trial (CAPT): Rationale, design and methodology. Clinical Trials 2004; 1:91-107.

2. The Age-Related Macular Degeneration Radiotherapy Trial (AMDRT) Research Group. (Ying GS as Biostatistician for the

Coordinating Center). The Age-Related Macular Degeneration Radiotherapy Trial (AMDRT): One year results from a pilot study. Am J Ophthalmol 2004; 138:818-28.

3. Vision In Preschoolers (VIP) Study Group. (Ying GS as Biostatistician for the Coordinating Center). Development and

implementation of a Preschool Vision Screening program in a mobile setting. NHSA Dialog 2005; 8:16-24. 4. Kulp MT, Vision in Preschoolers Study Group (Ying GS as Senior Biostatistician for the Coordinating Center). Findings

from the Vision in Preschoolers (VIP) Study. Optom Vis Sci. 2009; 86:619-23. 5. Soltz RA, Carolyn GH, Tolentino MJ, Maguire AM (Ying GS acknowledged). Transmission of retinal wavelengths though

blood. Retina 2005; 25:498-502. 6. Beltran WA, Hammond P, Acland GM, Aguirre GD (Ying GS acknowledged). A frameshift mutation in RPGR exon

ORF15 causes photoreceptor degeneration and inner retina remodeling in a model of X-linked retinitis pigmentosa. Invest Ophthalmol Vis Sci 2006; 47:1669-81.

7. Vision in Preschoolers (VIP) Study Group (Ying GS as Senior Biostatistician for the Coordinating Center). Predictive value

of photoscreening and traditional screening of preschool children. J AAPOS 2006; 10:377-8. 8. Vision In Preschoolers (VIP) Study Group (Ying GS as Senior Biostatistician for the Coordinating Center). Children unable

to perform screening tests in Vision In Preschoolers Study: Proportion with ocular conditions and impact on the measures of test accuracy. Invest Ophthalmol Vis Sci 2007; 48:83-87.

9. Vision In Preschoolers (VIP) Study Group (Ying GS as Senior Biostatistician for the Coordinating Center). Random Dot E

stereotest: Testability and reliability in 3- to 5-year-old children. J AAPOS 2006; 10:507-14. 10. Murphy BR, Moayedpardazi HS, Gewirtz AM, Diamond SL, Pierce EA (Ying GS acknowledged). Delivery and

mechanistic considerations for the production of knock-in mice by single-stranded olignucleotide gene targeting. Gene Therapy 2006; 5:1-12

11. Roman AJ, Boye SL, Aleman TS, Pang JJ, McDowell JH, Boye SE, Jacobson SG, Hauswirth WW (Ying GS

acknowledged). Electroretinographic analyses of Rpe65-mutant rd12 mice: Developing an in vivo bioassay for human gene therapy trials of Leber congenital amaurosis. Molecular Vision 2007;13:1701-10.

12. Ying X, Sulaiman P, Feddresen R, Liu J, Smith RG, Vardi N (Ying GS acknowledged). Retinal ON bipolar cells express

a new PCP2 splice variant that accelerates the light response. The Journal of Neuroscience 2008; 28:8873-84.

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13. Chen W, Stambolian D, Edwards AO et al (Ying GS as member of CAPT Data Coordinating Center acknowledged). Genetic variants TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci USA 2010; 107:7401-6.

EDITORIALS, LETTERS TO THE EDITOR, CHAPTERS, COMMITTEE REPORTS, PROCEEDINGS:

1. Ying GS, Huang XS. The methods for assaying the estrogenicity of environmental xenoestrogens (Review). Journal of Foreign Medicine - Public Health Division 1995; 22:216-9.

2. Ying GS. The primary culture of Sertoli cells and its use in testicular toxicity assay of diethylstilbestrol, casmium , and endosulfan. Master Thesis (advisor: Xingshu Huang). Zhejiang Medical University, Hangzhou, Zhejiang, June 1996.

3. Garabrant DH, Roth HD, Parsad R, Ying GS. Author reply Re: Latex sensitization in health care workers and in the US general population. Am J Epidemiol 2001; 153:527-8.

4. Garabrant DH, Roth HD, Parsad R, Ying GS. Author reply Re: Latex sensitization in health care workers and in the US general population. Am J Epidemiol 2001; 154:190-1.

5. Ying GS. Prediction of event times in randomized clinical trials. Ph.D. Dissertation (advisor: Daniel F Heitjan. Ph.D.). University of Pennsylvania, Philadelphia, Pennsylvania, May 2004.

6. Maguire MG, Fine SL, Ying GS. Intravitreal injection of VEGF siRNA (Correspondence). Retina 2005; 25: 101-2.

7. Ying GS, Liu CC. Analysis of the clustered data using SAS® systems. NESUG Conference Proceedings. 2006.

8. Mills MD, Orlin A, Ying GS. Response to a Letter to the Editor Re: A Comparison of Hang-Back with Conventional Recession Surgery for Exotropia. J AAPOS 2008; 12:215-6.

9. Mills MD, Quinn GE, Grunwald JE, Ying GS, Karp K, Rabinowitz M. Author Reply Re: Retinal vessels and Retinopathy of Prematurity. Archives of Ophthalmology 2008; 126:869-70.

10. Ying GS, Maguire MG. Account for correlation in regression analysis of longitudinal data from paired eyes. JSM

Proceedings 2008; 1190-97.

11. Ying GS. Is Drusen Really So Important? Invest Ophthalmol Vis Sci 2012;53:4407-4408.

12. Ciner EB, Ying GS, Kulp MT, Maguire MG, Quinn GE, Orel-Bixler D, Cyert LA, Moore B, Huang J. Author Reply Response: Stereoacuity of preschool children with and without vision disorders. Optom Vis Sci. 2014;91:e157-8.

13. Hagstrom SA, Ying GS, Maguire MG, Martin DF, for the CATT Research Group. Author Reply: Pharmacogenetics for genes associated with age-related macular degeneration in the Comparison of AMD Treatments Trials (CATT). Ophthalmology 2014;121:1663-4.

14. Ying GS. Predictors for the Development of Referral-Warranted Retinopathy of Prematurity. PracticeUpdate website. Available at: http://www.practiceupdate.com/c/21166/1/5. Accessed March 11, 2015. 15. Ying GS, Maguire MG. Author Reply RE: Analyses Comparing Visual Acuity between Ranibizumab and

Bevacizumab in in the Comparison of AMD Treatments Trials (CATT). JAMA Ophthalmology 2015; 133:726.

16. Bunya VY, Pistilli M, Ying GS. Progressively Increased Variation in Tear Osmolarity Mirrors Dry Eye Severity- Reply. JAMA Ophthalmol. 2015; 133:1482.

EDITORIALS, LETTERS TO THE EDITOR, CHAPTERS, COMMITTEE REPORTS, PROCEEDINGS (Cont’d):

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17. Binenbaum G, Ying GS. Role of Maternal Race on Algorithms Predicting Retinopathy of Prematurity-Reply. JAMA Ophthalmol. 2018; 136:221-222.

INVITED TALKS/LECTURES /WORKSHOPS/COURSES

1. Non-parametric prediction of event times in randomized clinical trials. ENAR Spring meeting. Pittsburgh, Pennsylvania. March, 2004.

2. Weibull predictions of event times in randomized clinical trials. Sanofi-Aventis, Malvern, PA. July 27, 2005.

3. Night-vision symptoms as a risk factor for vision loss, choroidal neovascularization, and geographic atrophy in

the Complications of Age-related Macular Degeneration Prevention Trial (CAPT). 131st Anniversary Meeting of Department of Ophthalmology, University of Pennsylvania. May, 2005.

4. Weibull predictions of event times in randomized clinical trials. 26th annual meeting of Society of Clinical Trials.

Portland, Oregon. May, 2005.

5. Predictions of patient enrollment in randomized clinical trials. 27th annual meeting of Society of Clinical Trials. Orlando, FL. May 23, 2006.

6. Real-time Predictions of event times in randomized clinical trials. New Researchers Meeting, Seattle, WA.

August 1-5, 2006.  

7. Analysis of clustered data using SAS® systems. NESUG 2006. Philadelphia, PA. September 19, 2006.

8. Night vision and risk of vision loss, choroidal neovascularization, and geographic atrophy in the Complications of age-related Macular Degeneration Prevention Trial (CAPT). 4th U.S. Symposium on Ocular Epidemiology. Sarasota, Florida. January 31, 2007.

9. Risk Factors for Choroidal Neovascularization (CNV) and Geographic Atrophy (GA) in the Complications of Age-

related Macular Degeneration Prevention Trial (CAPT). Association for Research in Vision and Ophthalmology Annual Meeting. Fort Lauderdale, Florida. May 8, 2007.

10. Real-time prediction of patient accrual and trial length that minimizes cost in randomized clinical trials. 28th

Society of Clinical Trial Annual Meeting. Montreal, Canada. May 22, 2007.

11. Different risk factors for Choroidal Neovascularization (CNV) and Geographic Atrophy (GA): Results from the Complications of Age-related Macular Degeneration Prevention Trial (CAPT). 133rd Anniversary Meeting of Department of Ophthalmology, University of Pennsylvania. June, 2007.

12. Account for correlation in regression analysis of longitudinal data from paired eyes. Joint Statistical Meeting, Denver, August 3, 2008.

13. Prediction of patient accrual and trial length that minimizes cost in randomized clinical trials. The First

International Symposium on Biopharmaceutical Statistics. Shanghai, China, June 30 – July 2, 2008.

14. Development of a Risk Score for Geographic Atrophy (GA) in Complications of Age-Related Macular Degeneration Prevention Trial (CAPT). Association for Research in Vision and Ophthalmology Annual Meeting. Fort Lauderdale, Florida. May 4, 2009.

15. Risk Score for Geographic Atrophy (GA) in Complications of Age-Related Macular Degeneration Prevention

Trial (CAPT). 135th Anniversary Meeting of Department of Ophthalmology, University of Pennsylvania. May

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27, 2009.

16. Biostatistician and Biostatistics—Today and the Future. School of Public Health, Zhejiang University. Hangzhou, Zhejiang, P.R. China. June 1, 2010.

17. Series of Introduction of Biostatistics. Zhejiang University. Hangzhou, Zhejiang, P.R. China. May 24-June 2,

2010.

18. Weibull prediction of event times in randomized clinical trials. PSI’s Pharmaceutical statistical journal club. October 27, 2010.

19. Introduction to Good Biostatistics Practice. Short course Director. International Conference on Good Medical

Research. Istanbul, Turkey, March 27, 2011.

20. Analysis of Correlated Eye Data. ARVO short course Director and Faculty Presenter. Association for Research in Vision and Ophthalmology Annual Meeting. Fort Lauderdale, Florida. April 30, 2011.

21. One Year Results of AMD comparison trials (CATT). Scheie Eye Institute Visiting Professor and Guest Lecture

Series, May 12. 2011.

22. Prediction in Randomized Clinical Trials. International Chinese Statistics Association Applied Statistics Symposium. June 26-28, 2011, New York City, New York.

23. Principles and concepts in clinical trials for eye researchers. One of the Invited speaker for ARVO Clinical Trials

Course. December 2-3, 2011, Shanghai, P.R.China.

24. Validation of geographic atrophy risk score in Age-related Eye Disease Participants. 137th Scheie Eye Institute Alumni Meeting. May 13, 2011.

25. Predictions in Clinical Trials. Roundtable Speaker. FDA/Industry Statistics Workshop. September 20, 2011.

Washington DC.

26. Evaluation of the medical diagnostic tests for correlated data. March 4, 2012. Omaha, Nebraska.

27. Baseline predictors for one year visual outcomes with Ranibizumab or Bevacizumab for Neovascular Age-related Macular Degeneration. Association for Research in Vision and Ophthalmology Annual Meeting. Fort Lauderdale, Florida. May 8, 2012.

28. Sustained Visual Acuity Loss in the Comparison of AMD Treatments Trials (CATT). Association for Research in

Vision and Ophthalmology Annual Meeting. Seattle, Washington. May 7, 2013.

29. Predictions in Clinical Trials. Department of Biostatistics, School of Public Health, University of Texas at Houston. March 22, 2013.

30. Real-time predictions in the REMATCH Trial. Division of Biostatistics, Jefferson University, Philadelphia. April

16, 2013.

31. Findings from the Comparison of AMD Treatments Trials (CATT). College of Optometry and Ophthalmology. Wenzhou University. P.R.China. August 28, 2013.

32. Findings from the Vision In Preschoolers Study (VIP). Zhongshan Eye Center, Guanzhou, P.R.China. August 18,

2014.

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33. Visual acuity response pattern and prediction in the Comparison of AMD Treatments Trials (CATT). Association for Research in Vision and Ophthalmology Annual Meeting. Orlando, Florida. May 4, 2014.

34. Association of antiplatelet and anticoagulant drugs with retinal hemorrhage in the Complications of Age-related

Macular Degeneration Treatments Trials. 141st Scheie Eye Institute Alumni Meeting. April 24, 2015.

35. Association of antiplatelet and anticoagulant drugs with retinal hemorrhage in the Complications of Age-related Macular Degeneration Treatments Trials. Association for Research in Vision and Ophthalmology Annual Meeting. Denver, Colorado. May 5, 2015.

36. Risk score for predicting development of treatment-requiring retinopathy of prematurity in the telemedicine

approaches to evaluating of acute-phase ROP (e-ROP) study. Association for Research in Vision and Ophthalmology Annual Meeting. Seattle, Washington. May 5, 2016.

37. Uncorrected hyperopia and preschool early literacy: Results of the Vision In Preschoolers – Hyperopia in

Preschoolers (VIP-HIP) Study. 42nd Annual Meeting for American Association for Pediatric Ophthalmology and Strabismus. Vancouver, BC, Canada. April 9, 2016.

38. Risk factors for plus disease in e-ROP study. IV ROP World Congress. Cancun, Mexico. August 31, 2017.

39. A Prediction Model for Retinopathy of Prematurity: Primary Results from the Postnatal Growth and ROP (G-ROP) Study ” AAPOS/CAPOS Annual Meeting, Shanghai, China. Oct 13, 2017.

40. Baseline predictors of 5-year visual acuity in the comparison of AMD treatments trials (CATT). 143rd Scheie Eye

Institute Alumni Meeting. April 13, 2018.

41. Characteristics of plus disease and accuracy of trained readers image grading for detecting plus disease in e-ROP Study. 144th Scheie Eye Institute Alumni Meeting. April 13, 2018.

42. Real-time prediction of event times in randomized clinical trials-an overview. ICSA 2018 Applied Statistics

Symposium. June 17, 2018.

Research Support Ongoing

R01 EY021137-01A1 Binenbaum (PI) 09/30/2012 – 12/31/2018 Title: Postnatal growth and retinopathy of prematurity (G-ROP) Major Goal: To develop a sensitive and specific ROP prognostic model that incorporates postnatal growth measurements with birth weight and gestational age to greatly reduce the number of infants requiring exams in the US. Role: Principal Investigator for the Data Coordinating Center

2-P30-EY01583-26 Brainard (PI) 09/01/15 – 08/31/2020 Title: Vision Research Center – Core Grant Major Goal: To further vision research activities through provision of biostatistical support. Role: Core grant biostatistical module Director

U10 EY022879 Maguire (PI) 09/01/2013 - 08/31/2019 Title: The Dry Eye Evaluation and Management (DREAM) Study Major Goal: To evaluate omega-3 fatty acid supplementation for treatment of of dry eye disease Role: Senior Biostatistician R01 EY-025287 (Ashtari) 04/01/2016 – 03/31/2021 NIH/NEI

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Title: Plasticity of the Human Visual System Studied in Response to Retinal Gene Therapy Major Goals: To study the process of vision restoration and its potential effects on the functional and structural plasticity of the human visual system in LCA2 patients who received gene therapy to receive normal RPE65 cDNA.

Role: Senior Biostatistician R01 EY026972 (Bunya) 09/30/16-08/31/2021 NEI/NIH Title: Developing New Methods for Early Detection of Sjogren's Syndrome Major Goal: To evaluate novel antibodies for their association with Sjogren Syndrome and identify systemic symptoms and ocular signs for developing prediction model for Sjogren Syndrome. Role: Co-investigator.

R21EY026717 (Kempen) 04/01/17-03/31/2019 NEI/NIH Title: Incidence of remission and of cataract in ocular inflammatory diseases Major Goal: To assess the incidence of remission and of cataract, and develop prediction models for remission and cataract in ocular inflammatory diseases Role: Senior Biostatistician. R01 EY022445 (Rosner) 04/01/2018-03/31/2021 NEI/NIH Title: Nonparametric and survival methods in ophthalmology. Major goal: To develop the nonparametric and survival methods and apply these methods to analyze real data from ophthalmic research. Role: PI of sub-contract.

Pending R21EY029776 – 01 (priority score 20) Ying (PI) 11/01/2018 – 10/30/2020

Title: Secondary Data Analysis of the data from G-ROP study Major Goal: To analyze the unique, rich datasets from G-ROP studies to evaluate and validate recently-

reported novel risk factors and protective factors for ROP; to develop and validate clinical tools using both traditional and novel risk factors for further stratifying ROP risk; and to propose incorporating these risk assessments into clinical guidelines to reduce the number of eye exams for infants who are receiving ROP examinations.

Role: Principal Investigator R21EY028998 – 01A1 (priority score 27) Ying (PI) 11/01/2018 – 10/30/2020 Title: Additional analyses of the data from the Comparison of Age-related Macular Degeneration Treatment Trials (CATT) and CATT Follow-up Study (CATT FS) Major Goal: To develop an early response score for predicting the long-term vision outcome from anti-

VEGF treatment for neovascular age-related macular degeneration, and to evaluate the association of medication use with the development and growth of geographic atrophy, to reduce the risk of vision loss in eyes treated with anti-VEGF.

Role: Principal Investigator Completed (last 5 years only)

U10EY017014 Quinn (PI) 07/01/2010 – 06/30/2016 Title: Telemedicine approaches to evaluating acute-phase ROP – e-ROP Major goal: To evaluate the validity, reliability, feasibility, safety and relative cost-effectiveness of an ROP telemedicine evaluation system to detect eyes of at-risk babies who meet RW-ROP criteria and therefore need of a diagnostic evaluation by an ophthalmologist experienced in ROP.

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Role: Principal Investigator for Data Coordinating Center

R21EY018908 Ying (PI) 08/01/2009 – 07/31/2012 Title: Analysis of data from Vision in Preschoolers (VIP) Study Major Goal: To evaluate the validity of four best screening tools for preschool vision screening, and to examination the vision disorders among Head Start preschoolers. Role: Principal Investigator

R21EY023689 – 01 Ying (PI) 09/01/2013 – 08/31/2016

Title: Secondary Data Analysis of the data from Comparison of AMD Treatment Trials Major Goal: To further elucidate the effects of the ranibizumab or bevacizumab on the visual and

morphologic outcomes, and their associations across the 2-year treatment period. Role: Principal Investigator U10 EY023530-01 Maguire (PI) 09/01/2013 – 08/31/2017 Title: Follow-up Study: Comparison of AMD Treatments Trial (CATT) Major Goal: To describe vision and morphological outcomes of patients treated with anti-VEGF agents

through approximately 5 years. Role: Senior Biostatistician U10-EY017823 Maguire (PI) 09/30/2006 – 01/31/2015 Title: Coordinating Center for the Comparison of AMD Treatments Trials Major Goal: To evaluate the relative efficacy and safety of anti-VEGF treatments for choroidal

neovascularization secondary to age-related macular degeneration. Role: Senior Biostatistician

R21EY023689 – 01 Ying (PI) 09/30/2015 – 08/31/2018 Title: Secondary Data Analysis of the data from the e-ROP Study Major Goal: To further evaluate the validity of telemedicine for ROP and to refine the system for image evaluation to optimize accuracy and efficiency.

Role: Principal Investigator