Exploration des donnes SAGE humainesAD Dico Challenge 3/11/2003

Sylvain Blachon (Doctorant EDIIS CGMC/LIRIS)

Sous la co tutelle de :J.F. Boulicaut (LIRIS)O. Gandrillon (CGMC)

Thse finance par la Ligue contre le cancer.

Question biologiqueEtude des cancers

Objectif : comprendre pourquoi certains groupes de gnes sont exprims par certaines tumeurs

Etude de lexpression des gnes par la technique SAGE

La technique SAGEMthode pour explorer le transcriptome

Avantages : donnes quantitatives =>comparaison entre expriences possibles ( linverse des puces)ADNARNmProtinesEnsemble des ARNm21111Ensemble des tags = Librairie SAGESituation biologique

Donnes SAGE humainesDonnes issues du Cancer Genome Anatomy Project : aujourdhui 260 librairies disponibles gratuitement sur Sage Genie (majoritairement Hs)Donnes de dcembre 2002 : 180 librairies humaines.Donnes htrognes (cellules de tissus ou en culture, beaucoup de tissus diffrents, cellules tumorales ou normales)Beaucoup dinfos manquantes

Exploration de ces donnesA la main : travail de titanMthode diffrentielle : limiteMthode globale :=> Matrice dexpression

tag1tag2tagnLib1Lib2Libm

Extraction de rgles biologiquement stimulantes :

Notre objectif

Exploration des donnes : techniques inductivesGrandes quantits de donnes => besoin doutils permettant dextraire des connaissances de ces donnesSchma classique :

Prtraitement des donnes (1/3)Donnes SAGE humaines : slection des librairies de plus de 20 000 tags squencs (Becquet et al)90 librairies

Graph1

26

518

27

29

20

47

11

11

10

30

26

20

10

12

10

10

10

10

normal

cancer

Organe

nombre de librairies

Rpartition cancer/normal des librairies SAGE par organe

Feuil2

organnormalcancertotal

colon268

brain51823

Ovary279

Prostate2911

vessel202

Breast4711

skin112

cerebellum112

thalamus101

kidney303

pancreas268

lymph node202

peritoneum101

stomach123

blood101

lung101

liver101

heart101

90

Feuil2

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00

00

00

00

00

00

00

00

00

00

00

00

00

00

00

00

00

normal

cancer

Organe

nombre de librairies

Rpartition cancer/normal des librairies SAGE par organe

Feuil1

numeroLibnomLibCancer ?organBulk/cell lineCancer typeNormal Cell typeTagskeywordCLASSE

8SAGE_BB542_whitematternobrainbulk94806brain normal SAGE CGAP non-normalized SAGE library method bulk

9SAGE_NHA(5th)nobraincell lineastrocyte52196brain normal SAGE astrocyte CGAP non-normalized SAGE library method cell line

10SAGE_normal_pool(6th)nobrainbulk63064brain normal SAGE CGAP non-normalized SAGE library method bulk

27SAGE_normal_cerebellumnoBrainbulk51135normal cerebellum bulk CGAP non-normalized SAGE library method bulk

85SAGE_normal_pediatric_cortex_H1571nobrainbulk77761normal cortex CGAP non-normalized SAGE library method bulk

Prtraitement des donnes (2/3)Slection des tags:Non ambigus (1 seul identifiant Unigene)Dont la quantit est dau moins 2 dans une librairie2 matrices dexpression humaines:74x822 : donnes de Juin 2001, slection du transcriptome minimal (Velculescu)90x27679 : donnes dcembre 2002

Prtraitement des donnes (3/3)Les biologistes dcident de coder des proprits dexpression => matrices boolennesNous nous intressons aux gnes surexprims => discrtisation de la matrice dexpressionon considre la valeur dexpression de chaque gne dans toutes les situations biologiqueson affecte 1 chaque fois que le gne est surexprimA ce jour, 3 techniques pour coder la surexpression dun gneLa discrtisation est une tape OUVERTE.

Exploration des donnes : techniques inductivesSchma classique :

2 types de motifs extraits :Rgles dassociation logiquesConcepts

Extraction de rgles dassociation (1/6)Rgles dassociation : X => YSi Gene A et Gene B surexprims => Gene C et Gene D surexprims aussiSupport(AB=>CD) = Supp(ABCD)Confiance (AB=>CD) = Supp(ABCD)/Supp(AB)Rgles logiques : confiance =1Cas concret :Si support minimal = 50%7 ensembles frquents :A, B, D, AB, AD, BD, ADB3 rgles logiques et frquentes :B=>AD=>ABD=>A

ABCD111012101031101

Extraction de rgles dassociation (2/6)Extraction sur la matrice 74x822 (Becquet et al, 2002)

Utilisation de lalgorithme Min-Ex :bas sur lextraction des ensembles libres partir libres, on extrait des rgles dont le membre gauche est minimal

Extraction de rgles dassociation (3/6)

Deux grands traits sont prsents :gnes ribosomauxgnes mitochondriaux A lintrieur dun jeu de rgles homogneR-identification dun gne mal identifiProposition de la fonction dune ESTPossibilit dassocier des cellules

Feuil1

ESTs, Weakly similar to B0334.4 [C.elegans]74,Voltage-dependent anion channel 1590:5

Tag matches mitochondrial sequence131,Tag matches mitochondrial sequence226:4

Homo sapiens RNA polymerase II transcription factor SIII p18 subunit mRNA, complete cds136,ESTs310:5

ESTs, Weakly similar to zinc finger protein [H.sapiens]138,ESTs536:5

IMP (inosine monophosphate) dehydrogenase 2152,Ribosomal protein, large, P0301:5

Tag matches mitochondrial sequence159,Tag matches mitochondrial sequence226:4

DEFENDER AGAINST CELL DEATH 1216,H.sapiens CDM mRNA622:5

Ribosomal protein S5270,Ribosomal protein, large, P0301Ribosomal protein L21348:5

ADENYLYL CYCLASE-ASSOCIATED PROTEIN 1306,Homo sapiens mRNA for follistain-related protein (FRP), complete cds336:5

Ribosomal protein L21348,Ribosomal protein S5270Ribosomal protein, large, P0301:5

Ribosomal protein L19364,GUANINE NUCLEOTIDE-BINDING PROTEIN BETA SUBUNIT-LIKE PROTEIN 12.3783:5

Protein phosphatase 1, catalytic subunit, alpha isoform395,ESTs453:5

ESTs, Weakly similar to No definition line found [C.elegans]514,ESTs310:5

Voltage-dependent anion channel 1590,ESTs, Weakly similar to B0334.4 [C.elegans]74:5

Adenosine A2b receptor611,Homo sapiens mRNA for KIAA0591 protein, partial cds265Homo sapiens tumor necrosis factor superfamily member LIGHT mRNA, complete cds415Homo sapiens RNA transcript from U17 small nucleolar RNA host gene, variant U17HG-AB618:4

Heterogeneous nuclear ribonucleoprotein A2/B1619,LARGE PROLINE-RICH PROTEIN BAT2574:5

H.sapiens CDM mRNA622,DEFENDER AGAINST CELL DEATH 1216:5

Triosephosphate isomerase 1719,ESTs, Weakly similar to No definition line found [C.elegans]740:5

ESTs, Weakly similar to No definition line found [C.elegans]740,Triosephosphate isomerase 1719:5

Homo sapiens F1F0-type ATP synthase subunit g mRNA, complete cds771,H.sapiens mRNA for NADH dehydrogenase172Calnexin781:5

ESTs, Weakly similar to neuroendocrine-specific protein C [H.sapiens]776,Homo sapiens mRNA for follistain-related protein (FRP), complete cds336:5

GUANINE NUCLEOTIDE-BINDING PROTEIN BETA SUBUNIT-LIKE PROTEIN 12.3783,Ribosomal protein L19364:5

PROTEASOME ZETA CHAIN784,ESTs453:5

Tag matches mitochondrial sequence1Tag matches mitochondrial sequence61,Tag matches mitochondrial sequence73Tag matches mitochondrial sequence99Tag matches mitochondrial sequence119Tag matches mitochondrial sequence166Tag matches mitochondrial sequence297Tag matches mitochondrial sequence299Homo sapiens mRNA for follistain-related protein (FRP), complete cds336Prostatic binding protein548ESTs808:2

Tag matches mitochondrial sequence1Tag matches mitochondrial sequence73,Tag matches mitochondrial sequence61Tag matches mitochondrial sequence99Tag matches mitochondrial sequence119Tag matches mitochondrial sequence166Tag matches mitochondrial sequence297Tag matches mitochondrial sequence299Homo sapiens mRNA for follistain-related protein (FRP), complete cds336Prostatic binding protein548ESTs808:2

Tag matches mitochondrial sequence1Tag matches mitochondrial sequence89,Tag matches mitochondrial sequence99Tag matches mitochondrial sequence166Tag matches mitochondrial sequence176Tag matches mitochondrial sequence299Tag matches mitochondrial sequence417Tag matches mitochondrial sequence433Prostatic binding protein548Human 150 kDa oxygen-regulated protein ORP150 mRNA, complete cds570Tag matches mitochondrial sequence688Tag matches mitochondrial sequence788Homo sapiens phosphoprotein CtBP mRNA, complete cds817:2

Tag matches mitochondrial sequence1Tag matches mitochondrial sequence99,Tag matches mitochondrial sequence166Tag matches mitochondrial sequence299Prostatic binding protein548:3

Tag matches mitochondrial sequence1Tag matches mitochondrial sequence119,Tag matches mitochondrial sequence61Tag matches mitochondrial sequence73Tag matches mitochondrial sequence99Tag matches mitochondrial sequence166Tag matches mitochondrial sequence297Tag matches mitochondrial sequence299Homo sapiens mRNA for follistain-related protein (FRP), complete cds336Prostatic binding protein548ESTs808:2

Tag matches mitochondrial sequence1Tag matches mitochondrial sequence166,Tag matches mitochondrial sequence99Tag matches mitochondrial sequence299Prostatic binding protein548:3

Tag matches mitochondrial sequence1Tag matches mitochondrial sequence176,Tag matches mitochondrial sequence89Tag matches mitochondrial sequence99Tag matches mitochondrial sequence166Tag matches mitochondrial sequence299Tag matches mitochondrial sequence417Tag matches mitochondrial sequence433Prostatic binding protein548Human 150 kDa oxygen-regulated protein ORP150 mRNA, complete cds570Tag matches mitochondrial sequence688Tag matches mitochondrial sequence788Homo sapiens phosphoprotein CtBP mRNA, complete cds817:2

Tag matches mitochondrial sequence1Tag matches mitochondrial sequence299,Tag matches mitochondrial sequence99Tag matches mitochondrial sequence166Prostatic binding protein548:3

Tag matches mitochondrial sequence1Tag matches mitochondrial sequence304,Tag matches mitochondrial sequence297ATPase, H+ transporting, lysosomal (vacuolar proton pump) 31kD489:2

Tag matches mitochondrial sequence1Homo sapiens mRNA for follistain-related protein (FRP), complete cds336,Tag matches mitochondrial sequence61Tag matches mitochondrial sequence73Tag matches mitochondrial sequence99Tag matches mitochondrial sequence119Tag matches mitochondrial sequence166Tag matches mitochondrial sequence297Tag matches mitochondrial sequence299Prostatic binding protein548ESTs808:2

Tag matches mitochondrial sequence1Tag matches mitochondrial sequence417,Tag matches mitochondrial sequence89Tag matches mitochondrial sequence99Tag matches mitochondrial sequence166Tag matches mitochondrial sequence176Tag matches mitochondrial sequence299Tag matches mitochondrial sequence433Prostatic binding protein548Human 150 kDa oxygen-regulated protein ORP150 mRNA, complete cds570Tag matches mitochondrial sequence688Tag matches mitochondrial sequence788Homo sapiens phosphoprotein CtBP mRNA, complete cds817:2

Tag matches mitochondrial sequence1Tag matches mitochondrial sequence433,Tag matches mitochondrial sequence89Tag matches mitochondrial sequence99Tag matches mitochondrial sequence166Tag matches mitochondrial sequence176Tag matches mitochondrial sequence299Tag matches mitochondrial sequence417Prostatic binding protein548Human 150 kDa oxygen-regulated protein ORP150 mRNA, complete cds570Tag matches mitochondrial sequence688Tag matches mitochondrial sequence788Homo sapiens phosphoprotein CtBP mRNA, complete cds817:2

Tag matches mitochondrial sequence1ATPase, H+ transporting, lysosomal (vacuolar proton pump) 31kD489,Tag matches mitochondrial sequence297Tag matches mitochondrial sequence304:2

Tag matches mitochondrial sequence1Human 150 kDa oxygen-regulated protein ORP150 mRNA, complete cds570,Prostatic binding protein548:3

Tag matches mitochondrial sequence1ESTs594,Prostatic binding protein548Homo sapiens CD39L2 (CD39L2) mRNA, complete cds777:2

Tag matches mitochondrial sequence1Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide663,Tag matches mitochondrial sequence99Tag matches mitochondrial sequence166Tag matches mitochondrial sequence299Prostatic binding protein548Calmodulin 1 (phosphorylase kinase, delta)810:2

Tag matches mitochondrial sequence1Homo sapiens flotillin-1 mRNA, complete cds671,Prostatic binding protein548Human 150 kDa oxygen-regulated protein ORP150 mRNA, complete cds570:2

Tag matches mitochondrial sequence1Human enhancer of rudimentary homolog mRNA, complete cds684,Sign(al recognition particle 14 kD protein703:2

Tag matches mitochondrial sequence1Tag matches mitochondrial sequence688,Tag matches mitochondrial sequence89Tag matches mitochondrial sequence99Tag matches mitochondrial sequence166Tag matches mitochondrial sequence176Tag matches mitochondrial sequence299Tag matches mitochondrial sequence417Tag matches mitochondrial sequence433Prostatic binding protein548Human 150 kDa oxygen-regulated protein ORP150 mRNA, complete cds570Tag matches mitochondrial sequence788Homo sapiens phosphoprotein CtBP mRNA, complete cds817:2

Tag matches mitochondrial sequence1Sign(al recognition particle 14 kD protein703,Human enhancer of rudimentary homolog mRNA, complete cds684:2

Tag matches mitochondrial sequence1Homo sapiens CD39L2 (CD39L2) mRNA, complete cds777,Prostatic binding protein548ESTs594:2

Tag matches mitochondrial sequence1Tag matches mitochondrial sequence788,Tag matches mitochondrial sequence89Tag matches mitochondrial sequence99Tag matches mitochondrial sequence166Tag matches mitochondrial sequence176Tag matches mitochondrial sequence299Tag matches mitochondrial sequence417Tag matches mitochondrial sequence433Prostatic binding protein548Human 150 kDa oxygen-regulated protein ORP150 mRNA, complete cds570Tag matches mitochondrial sequence688Homo sapiens phosphoprotein CtBP mRNA, complete cds817:2

Tag matches mitochondrial sequence1ESTs808,Tag matches mitochondrial sequence61Tag matches mitochondrial sequence73Tag matches mitochondrial sequence99Tag matches mitochondrial sequence119Tag matches mitochondrial sequence166Tag matches mitochondrial sequence297Tag matches mitochondrial sequence299Homo sapiens mRNA for follistain-related protein (FRP), complete cds336Prostatic binding protein548:2

Tag matches mitochondrial sequence1Calmodulin 1 (phosphorylase kinase, delta)810,Tag matches mitochondrial sequence99Tag matches mitochondrial sequence166Tag matches mitochondrial sequence299Prostatic binding protein548Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide663:2

Tag matches mitochondrial sequence1Tag matches mitochondrial sequence811,Tag matches mitochondrial sequence297:2

Tag matches mitochondrial sequence1Homo sapiens phosphoprotein CtBP mRNA, complete cds817,Tag matches mitochondrial sequence89Tag matches mitochondrial sequence99Tag matches mitochondrial sequence166Tag matches mitochondrial sequence176Tag matches mitochondrial sequence299Tag matches mitochondrial sequence417Tag matches mitochondrial sequence433Prostatic binding protein548Human 150 kDa oxygen-regulated protein ORP150 mRNA, complete cds570Tag matches mitochondrial sequence688Tag matches mitochondrial sequence788:2

POLYADENYLATE-BINDING PROTEIN2Human translation initiation factor eIF3 p40 subunit mRNA, complete cds16,Human translation initiation factor eIF3 p66 subunit mRNA, complete cds32HEAT SHOCK PROTEIN HSP 90-BETA593:3

POLYADENYLATE-BINDING PROTEIN2Human translation initiation factor eIF3 p66 subunit mRNA, complete cds32,Human translation initiation factor eIF3 p40 subunit mRNA, complete cds16HEAT SHOCK PROTEIN HSP 90-BETA593:3

POLYADENYLATE-BINDING PROTEIN2Human DNA from chromosome 19-specific cosmid R27090, genomic sequence63,Eukaryotic translation elongation factor 292ESTs125Solute carrier family 5 (sodium/glucose cotransporter), member 2211Proteasome (prosome, macropain) subunit, beta type, 6397ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2466H.sapiens mRNA for mediator of receptor-induced toxicity480HEAT SHOCK PROTEIN HSP 90-BETA515Homo sapiens dbpB-like protein mRNA, complete cds555Homo sapiens DBI-related protein mRNA, complete cds675C4/C2 activating component of Ra-reactive factor769Translation elongation factor 1-alpha-1775:2

POLYADENYLATE-BINDING PROTEIN2Homo sapiens clone 23675 mRNA sequence66,Solute carrier family 5 (sodium/glucose cotransporter), member 2211Testis enhanced gene transcript214Adrenergic, beta, receptor kinase 1231H.sapiens mRNA for TRAMP protein326Homo sapiens mRNA for putative seven transmembrane domain protein (Signal)63014-3-3 PROTEIN TAU (Signal)714:2

POLYADENYLATE-BINDING PROTEIN2HEAT SHOCK PROTEIN HSP 90-ALPHA69,Human translation initiation factor eIF3 p40 subunit mRNA, complete cds16Human translation initiation factor eIF3 p66 subunit mRNA, complete cds32ESTs, Weakly similar to CASEIN KINASE I HOMOLOG HRR25 [Saccharomyces cerevisiae]133V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 {alternative products} (Signal)264HEAT SHOCK PROTEIN HSP 90-ALPHA369HEAT SHOCK PROTEIN HSP 90-BETA593:2

POLYADENYLATE-BINDING PROTEIN2ESTs125,Human DNA from chromosome 19-specific cosmid R27090, genomic sequence63Eukaryotic translation elongation factor 292Solute carrier family 5 (sodium/glucose cotransporter), member 2211Proteasome (prosome, macropain) subunit, beta type, 6397ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2466H.sapiens mRNA for mediator of receptor-induced toxicity480HEAT SHOCK PROTEIN HSP 90-BETA515Homo sapiens dbpB-like protein mRNA, complete cds555Homo sapiens DBI-related protein mRNA, complete cds675C4/C2 activating component of Ra-reactive factor769Translation elongation factor 1-alpha-1775:2

POLYADENYLATE-BINDING PROTEIN2ESTs, Weakly similar to CASEIN KINASE I HOMOLOG HRR25 [Saccharomyces cerevisiae]133,Human translation initiation factor eIF3 p40 subunit mRNA, complete cds16Human translation initiation factor eIF3 p66 subunit mRNA, complete cds32HEAT SHOCK PROTEIN HSP 90-ALPHA69V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 {alternative products} (Signal)264HEAT SHOCK PROTEIN HSP 90-ALPHA369HEAT SHOCK PROTEIN HSP 90-BETA593:2

POLYADENYLATE-BINDING PROTEIN2ESTs147,Human B-cell receptor associated protein (hBAP) mRNA, partial cds276Proteasome component C2584Human siah binding protein 1 (SiahBP1) mRNA, partial cds603Human mRNA for KIAA0088 gene, partial cds773:2

POLYADENYLATE-BINDING PROTEIN2Testis enhanced gene transcript214,Homo sapiens clone 23675 mRNA sequence66Solute carrier family 5 (sodium/glucose cotransporter), member 2211Adrenergic, beta, receptor kinase 1231H.sapiens mRNA for TRAMP protein326Homo sapiens mRNA for putative seven transmembrane domain protein (Signal)63014-3-3 PROTEIN TAU (Signal)714:2

POLYADENYLATE-BINDING PROTEIN2GLYCOPROTEIN HORMONES ALPHA CHAIN PRECURSOR217,Human translation initiation factor eIF3 p40 subunit mRNA, complete cds16Human translation initiation factor eIF3 p66 subunit mRNA, complete cds32Homo sapiens mRNA for Hrs, complete cds586HEAT SHOCK PROTEIN HSP 90-BETA593:2

POLYADENYLATE-BINDING PROTEIN2Adrenergic, beta, receptor kinase 1231,Homo sapiens clone 23675 mRNA sequence66Solute carrier family 5 (sodium/glucose cotransporter), member 2211Testis enhanced gene transcript214H.sapiens mRNA for TRAMP protein326Homo sapiens mRNA for putative seven transmembrane domain protein (Signal)63014-3-3 PROTEIN TAU (Signal)714:2

POLYADENYLATE-BINDING PROTEIN2ESTs, Weakly similar to ALBUMIN B-32 PROTEIN [Zea mays]260,Eukaryotic translation elongation factor 292Ribosomal protein L4283:2

POLYADENYLATE-BINDING PROTEIN2V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 {alternative products} (Signal)264,Human translation initiation factor eIF3 p40 subunit mRNA, complete cds16Human translation initiation factor eIF3 p66 subunit mRNA, complete cds32HEAT SHOCK PROTEIN HSP 90-ALPHA69ESTs, Weakly similar to CASEIN KINASE I HOMOLOG HRR25 [Saccharomyces cerevisiae]133HEAT SHOCK PROTEIN HSP 90-ALPHA369HEAT SHOCK PROTEIN HSP 90-BETA593:2

POLYADENYLATE-BINDING PROTEIN2Human B-cell receptor associated protein (hBAP) mRNA, partial cds276,ESTs147Proteasome component C2584Human siah binding protein 1 (SiahBP1) mRNA, partial cds603Human mRNA for KIAA0088 gene, partial cds773:2

POLYADENYLATE-BINDING PROTEIN2Ribosomal protein L4283,Eukaryotic translation elongation factor 292ESTs, Weakly similar to ALBUMIN B-32 PROTEIN [Zea mays]260:2

POLYADENYLATE-BINDING PROTEIN2H.sapiens mRNA for TRAMP protein326,Homo sapiens clone 23675 mRNA sequence66Solute carrier family 5 (sodium/glucose cotransporter), member 2211Testis enhanced gene transcript214Adrenergic, beta, receptor kinase 1231Homo sapiens mRNA for putative seven transmembrane domain protein (Signal)63014-3-3 PROTEIN TAU (Signal)714:2

POLYADENYLATE-BINDING PROTEIN2HEAT SHOCK PROTEIN HSP 90-ALPHA369,Human translation initiation factor eIF3 p40 subunit mRNA, complete cds16Human translation initiation factor eIF3 p66 subunit mRNA, complete cds32HEAT SHOCK PROTEIN HSP 90-ALPHA69ESTs, Weakly similar to CASEIN KINASE I HOMOLOG HRR25 [Saccharomyces cerevisiae]133V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 {alternative products} (Signal)264HEAT SHOCK PROTEIN HSP 90-BETA593:2

POLYADENYLATE-BINDING PROTEIN2ESTs, Highly similar to HYPOTHETICAL 37.2 KD PROTEIN C12C2.09C IN CHROMOSOME I [Schizosaccharomyces pombe]371,Solute carrier family 5 (sodium/glucose cotransporter), member 2211Glycyl-tRNA synthetase519Myeloid cell leukemia sequence 1 (BCL2-related)644Calmodulin 1 (phosphorylase kinase, delta)810:2

POLYADENYLATE-BINDING PROTEIN2Proteasome (prosome, macropain) subunit, beta type, 6397,Human DNA from chromosome 19-specific cosmid R27090, genomic sequence63Eukaryotic translation elongation factor 292ESTs125Solute carrier family 5 (sodium/glucose cotransporter), member 2211ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2466H.sapiens mRNA for mediator of receptor-induced toxicity480HEAT SHOCK PROTEIN HSP 90-BETA515Homo sapiens dbpB-like protein mRNA, complete cds555Homo sapiens DBI-related protein mRNA, complete cds675C4/C2 activating component of Ra-reactive factor769Translation elongation factor 1-alpha-1775:2

POLYADENYLATE-BINDING PROTEIN2ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2466,Human DNA from chromosome 19-specific cosmid R27090, genomic sequence63Eukaryotic translation elongation factor 292ESTs125Solute carrier family 5 (sodium/glucose cotransporter), member 2211Proteasome (prosome, macropain) subunit, beta type, 6397H.sapiens mRNA for mediator of receptor-induced toxicity480HEAT SHOCK PROTEIN HSP 90-BETA515Homo sapiens dbpB-like protein mRNA, complete cds555Homo sapiens DBI-related protein mRNA, complete cds675C4/C2 activating component of Ra-reactive factor769Translation elongation factor 1-alpha-1775:2

POLYADENYLATE-BINDING PROTEIN2H.sapiens mRNA for mediator of receptor-induced toxicity480,Human DNA from chromosome 19-specific cosmid R27090, genomic sequence63Eukaryotic translation elongation factor 292ESTs125Solute carrier family 5 (sodium/glucose cotransporter), member 2211Proteasome (prosome, macropain) subunit, beta type, 6397ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2466HEAT SHOCK PROTEIN HSP 90-BETA515Homo sapiens dbpB-like protein mRNA, complete cds555Homo sapiens DBI-related protein mRNA, complete cds675C4/C2 activating component of Ra-reactive factor769Translation elongation factor 1-alpha-1775:2

POLYADENYLATE-BINDING PROTEIN2HEAT SHOCK PROTEIN HSP 90-BETA515,Human DNA from chromosome 19-specific cosmid R27090, genomic sequence63Eukaryotic translation elongation factor 292ESTs125Solute carrier family 5 (sodium/glucose cotransporter), member 2211Proteasome (prosome, macropain) subunit, beta type, 6397ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2466H.sapiens mRNA for mediator of receptor-induced toxicity480Homo sapiens dbpB-like protein mRNA, complete cds555Homo sapiens DBI-related protein mRNA, complete cds675C4/C2 activating component of Ra-reactive factor769Translation elongation factor 1-alpha-1775:2

POLYADENYLATE-BINDING PROTEIN2Glycyl-tRNA synthetase519,Solute carrier family 5 (sodium/glucose cotransporter), member 2211ESTs, Highly similar to HYPOTHETICAL 37.2 KD PROTEIN C12C2.09C IN CHROMOSOME I [Schizosaccharomyces pombe]371Myeloid cell leukemia sequence 1 (BCL2-related)644Calmodulin 1 (phosphorylase kinase, delta)810:2

POLYADENYLATE-BINDING PROTEIN2Homo sapiens dbpB-like protein mRNA, complete cds555,Human DNA from chromosome 19-specific cosmid R27090, genomic sequence63Eukaryotic translation elongation factor 292ESTs125Solute carrier family 5 (sodium/glucose cotransporter), member 2211Proteasome (prosome, macropain) subunit, beta type, 6397ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2466H.sapiens mRNA for mediator of receptor-induced toxicity480HEAT SHOCK PROTEIN HSP 90-BETA515Homo sapiens DBI-related protein mRNA, complete cds675C4/C2 activating component of Ra-reactive factor769Translation elongation factor 1-alpha-1775:2

POLYADENYLATE-BINDING PROTEIN2Proteasome component C2584,ESTs147Human B-cell receptor associated protein (hBAP) mRNA, partial cds276Human siah binding protein 1 (SiahBP1) mRNA, partial cds603Human mRNA for KIAA0088 gene, partial cds773:2

POLYADENYLATE-BINDING PROTEIN2Homo sapiens mRNA for Hrs, complete cds586,Human translation initiation factor eIF3 p40 subunit mRNA, complete cds16Human translation initiation factor eIF3 p66 subunit mRNA, complete cds32GLYCOPROTEIN HORMONES ALPHA CHAIN PRECURSOR217HEAT SHOCK PROTEIN HSP 90-BETA593:2

POLYADENYLATE-BINDING PROTEIN2HEAT SHOCK PROTEIN HSP 90-BETA593,Human translation initiation factor eIF3 p40 subunit mRNA, complete cds16Human translation initiation factor eIF3 p66 subunit mRNA, complete cds32:3

POLYADENYLATE-BINDING PROTEIN2Human siah binding protein 1 (SiahBP1) mRNA, partial cds603,ESTs147Human B-cell receptor associated protein (hBAP) mRNA, partial cds276Proteasome component C2584Human mRNA for KIAA0088 gene, partial cds773:2

POLYADENYLATE-BINDING PROTEIN2Homo sapiens mRNA for putative seven transmembrane domain protein (Signal)630,Homo sapiens clone 23675 mRNA sequence66Solute carrier family 5 (sodium/glucose cotransporter), member 2211Testis enhanced gene transcript214Adrenergic, beta, receptor kinase 1231H.sapiens mRNA for TRAMP protein32614-3-3 PROTEIN TAU (Signal)714:2

POLYADENYLATE-BINDING PROTEIN2Myeloid cell leukemia sequence 1 (BCL2-related)644,Solute carrier family 5 (sodium/glucose cotransporter), member 2211ESTs, Highly similar to HYPOTHETICAL 37.2 KD PROTEIN C12C2.09C IN CHROMOSOME I [Schizosaccharomyces pombe]371Glycyl-tRNA synthetase519Calmodulin 1 (phosphorylase kinase, delta)810:2

POLYADENYLATE-BINDING PROTEIN2Homo sapiens DBI-related protein mRNA, complete cds675,Human DNA from chromosome 19-specific cosmid R27090, genomic sequence63Eukaryotic translation elongation factor 292ESTs125Solute carrier family 5 (sodium/glucose cotransporter), member 2211Proteasome (prosome, macropain) subunit, beta type, 6397ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2466H.sapiens mRNA for mediator of receptor-induced toxicity480HEAT SHOCK PROTEIN HSP 90-BETA515Homo sapiens dbpB-like protein mRNA, complete cds555C4/C2 activating component of Ra-reactive factor769Translation elongation factor 1-alpha-1775:2

POLYADENYLATE-BINDING PROTEIN214-3-3 PROTEIN TAU (Signal)714,Homo sapiens clone 23675 mRNA sequence66Solute carrier family 5 (sodium/glucose cotransporter), member 2211Testis enhanced gene transcript214Adrenergic, beta, receptor kinase 1231H.sapiens mRNA for TRAMP protein326Homo sapiens mRNA for putative seven transmembrane domain protein (Signal)630:2

POLYADENYLATE-BINDING PROTEIN2C4/C2 activating component of Ra-reactive factor769,Human DNA from chromosome 19-specific cosmid R27090, genomic sequence63Eukaryotic translation elongation factor 292ESTs125Solute carrier family 5 (sodium/glucose cotransporter), member 2211Proteasome (prosome, macropain) subunit, beta type, 6397ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2466H.sapiens mRNA for mediator of receptor-induced toxicity480HEAT SHOCK PROTEIN HSP 90-BETA515Homo sapiens dbpB-like protein mRNA, complete cds555Homo sapiens DBI-related protein mRNA, complete cds675Translation elongation factor 1-alpha-1775:2

POLYADENYLATE-BINDING PROTEIN2Human mRNA for KIAA0088 gene, partial cds773,ESTs147Human B-cell receptor associated protein (hBAP) mRNA, partial cds276Proteasome component C2584Human siah binding protein 1 (SiahBP1) mRNA, partial cds603:2

POLYADENYLATE-BINDING PROTEIN2Translation elongation factor 1-alpha-1775,Human DNA from chromosome 19-specific cosmid R27090, genomic sequence63Eukaryotic translation elongation factor 292ESTs125Solute carrier family 5 (sodium/glucose cotransporter), member 2211Proteasome (prosome, macropain) subunit, beta type, 6397ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2466H.sapiens mRNA for mediator of receptor-induced toxicity480HEAT SHOCK PROTEIN HSP 90-BETA515Homo sapiens dbpB-like protein mRNA, complete cds555Homo sapiens DBI-related protein mRNA, complete cds675C4/C2 activating component of Ra-reactive factor769:2

POLYADENYLATE-BINDING PROTEIN2Calmodulin 1 (phosphorylase kinase, delta)810,Solute carrier family 5 (sodium/glucose cotransporter), member 2211ESTs, Highly similar to HYPOTHETICAL 37.2 KD PROTEIN C12C2.09C IN CHROMOSOME I [Schizosaccharomyces pombe]371Glycyl-tRNA synthetase519Myeloid cell leukemia sequence 1 (BCL2-related)644:2

Feuil2

Feuil3

Feuil1

kidney. normal. cell line. embryo. CGAP. non-normalized. SAGE library method. cell line.2prostate. carcinoma. bulk.17,prostate. carcinoma. cell line.14:35

prostate. carcinoma. bulk.17prostate. carcinoma. cell line.19,prostate. carcinoma. cell line.14prostate. normal. bulk.16:31

prostate. carcinoma. bulk.17prostate. normal. microdissected. CGAP. non-normalized. SAGE library method. microdissected.66,prostate. carcinoma. cell line.14:20

prostate. carcinoma. bulk.17mammary gland. carcinoma. cell line. estrogen.70,prostate. carcinoma. cell line.14:30

kidney. normal. cell line. embryo. CGAP. non-normalized. SAGE library method. cell line.1prostate. carcinoma. cell line.14prostate. carcinoma. cell line.18,prostate. normal. bulk.16:20

kidney. normal. cell line. embryo. CGAP. non-normalized. SAGE library method. cell line.1prostate. carcinoma. cell line.14prostate. carcinoma. cell line.19,prostate. normal. bulk.16:18

kidney. normal. cell line. embryo. CGAP. non-normalized. SAGE library method. cell line.1prostate. normal. bulk.16brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30,prostate. carcinoma. cell line.14:21

kidney. normal. cell line. embryo. CGAP. non-normalized. SAGE library method. cell line.1prostate. carcinoma. bulk.17brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30,prostate. carcinoma. cell line.14:20

kidney. normal. cell line. embryo. CGAP. non-normalized. SAGE library method. cell line.2prostate. carcinoma. cell line.14prostate. carcinoma. cell line.19,prostate. normal. bulk.16:20

kidney. normal. cell line. embryo. CGAP. non-normalized. SAGE library method. cell line.2prostate. carcinoma. cell line.15prostate. normal. bulk.16,prostate. carcinoma. cell line.14:30

kidney. normal. cell line. embryo. CGAP. non-normalized. SAGE library method. cell line.2prostate. carcinoma. cell line.15prostate. carcinoma. cell line.18,prostate. carcinoma. cell line.14:17

kidney. normal. cell line. embryo. CGAP. non-normalized. SAGE library method. cell line.2prostate. carcinoma. cell line.15brain. astrocytoma. bulk.27,prostate. carcinoma. cell line.14:24

kidney. normal. cell line. embryo. CGAP. non-normalized. SAGE library method. cell line.2prostate. carcinoma. cell line.15brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30,prostate. carcinoma. cell line.14:22

kidney. normal. cell line. embryo. CGAP. non-normalized. SAGE library method. cell line.2prostate. carcinoma. cell line.15prostate. adenocarcinoma. microdissected. CGAP. non-normalized. SAGE library method. microdissected.67,prostate. carcinoma. cell line.14:19

kidney. normal. cell line. embryo. CGAP. non-normalized. SAGE library method. cell line.2prostate. normal. bulk.16prostate. carcinoma. cell line.18,prostate. carcinoma. cell line.14:21

kidney. normal. cell line. embryo. CGAP. non-normalized. SAGE library method. cell line.2prostate. normal. bulk.16brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30,prostate. carcinoma. cell line.14:23

kidney. normal. cell line. embryo. CGAP. non-normalized. SAGE library method. cell line.2prostate. normal. bulk.16pancreas. epithelium. ductal. normal. cell line. CGAP. non-normalized. SAGE library method. cell line.41,prostate. carcinoma. cell line.14:19

kidney. normal. cell line. embryo. CGAP. non-normalized. SAGE library method. cell line.2prostate. carcinoma. bulk.17brain. astrocytoma. bulk.27,prostate. carcinoma. cell line.14prostate. normal. bulk.16:18

kidney. normal. cell line. embryo. CGAP. non-normalized. SAGE library method. cell line.2prostate. carcinoma. bulk.17pancreas. epithelium. ductal. normal. cell line. CGAP. non-normalized. SAGE library method. cell line.41,prostate. carcinoma. cell line.14prostate. normal. bulk.16:17

prostate. carcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.7prostate. normal. bulk.16brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30,prostate. carcinoma. cell line.15:21

ovary. carcinoma. SAGE. cell line. CGAP. non-normalized. SAGE library method. cell line.8prostate. carcinoma. cell line.15prostate. normal. bulk.16,prostate. carcinoma. cell line.14:19

pancreas. adenocarcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.12prostate. carcinoma. cell line.15prostate. normal. bulk.16,prostate. carcinoma. cell line.14:22

pancreas. adenocarcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.12prostate. carcinoma. cell line.15prostate. carcinoma. bulk.17,prostate. carcinoma. cell line.14:21

pancreas. adenocarcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.13prostate. carcinoma. cell line.14prostate. carcinoma. bulk.17,prostate. carcinoma. cell line.15:17

pancreas. adenocarcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.13prostate. carcinoma. cell line.15prostate. adenocarcinoma. microdissected. CGAP. non-normalized. SAGE library method. microdissected.67,prostate. carcinoma. cell line.14:18

pancreas. adenocarcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.13prostate. normal. bulk.16prostate. carcinoma. bulk.17,prostate. carcinoma. cell line.15:18

prostate. carcinoma. cell line.14prostate. carcinoma. bulk.17ovary. clear cell. poorly differentiated. carcinoma. CGAP. non-normalized. SAGE library method. cell line.40,prostate. normal. bulk.16:18

prostate. carcinoma. cell line.14prostate. carcinoma. cell line.19brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30,prostate. normal. bulk.16prostate. carcinoma. bulk.17prostate. carcinoma. cell line.18:18

prostate. carcinoma. cell line.14brain. astrocytoma. bulk.27brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30,prostate. carcinoma. cell line.15:25

prostate. carcinoma. cell line.14brain. astrocytoma. bulk.27medulloblastoma. SAGE. brain stem. CGAP. non-normalized. SAGE library method. cell line.36,prostate. carcinoma. cell line.15:19

prostate. carcinoma. cell line.14brain. astrocytoma. bulk.27prostate. adenocarcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.47,prostate. carcinoma. cell line.15:18

prostate. carcinoma. cell line.14brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30pancreas. epithelium. ductal. normal. cell line. CGAP. non-normalized. SAGE library method. cell line.41,prostate. carcinoma. cell line.15:22

prostate. carcinoma. cell line.14brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30pancreas. epithelium. ductal. normal. cell line. CGAP. non-normalized. SAGE library method. cell line.44,prostate. carcinoma. cell line.15:22

prostate. carcinoma. cell line.14brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30prostate. adenocarcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.47,prostate. carcinoma. cell line.15:21

prostate. carcinoma. cell line.15prostate. normal. bulk.16brain. astrocytoma. bulk.27,prostate. carcinoma. cell line.14:31

prostate. carcinoma. cell line.15prostate. normal. bulk.16medulloblastoma. SAGE. brain stem. CGAP. non-normalized. SAGE library method. cell line.36,prostate. carcinoma. cell line.14:25

prostate. carcinoma. cell line.15prostate. normal. bulk.16prostate. normal. microdissected. CGAP. non-normalized. SAGE library method. microdissected.66,prostate. carcinoma. cell line.14:18

prostate. carcinoma. cell line.15prostate. normal. bulk.16mammary gland. carcinoma. cell line.69,prostate. carcinoma. cell line.14:22

prostate. carcinoma. cell line.15prostate. normal. bulk.16mammary gland. carcinoma. cell line. estrogen.70,prostate. carcinoma. cell line.14:28

prostate. carcinoma. cell line.15prostate. normal. bulk.16mammary gland. carcinoma. cell line. estrogen.71,prostate. carcinoma. cell line.14:23

prostate. carcinoma. cell line.15prostate. carcinoma. bulk.17prostate. adenocarcinoma. microdissected. CGAP. non-normalized. SAGE library method. microdissected.67,prostate. carcinoma. cell line.14:28

prostate. carcinoma. cell line.15prostate. carcinoma. bulk.17mammary gland. carcinoma. cell line.69,prostate. carcinoma. cell line.14:20

prostate. carcinoma. cell line.15prostate. normal. microdissected. CGAP. non-normalized. SAGE library method. microdissected.66prostate. adenocarcinoma. microdissected. CGAP. non-normalized. SAGE library method. microdissected.67,prostate. carcinoma. cell line.14:19

prostate. normal. bulk.16prostate. carcinoma. bulk.17brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30,prostate. carcinoma. cell line.14:34

prostate. normal. bulk.16prostate. carcinoma. bulk.17medulloblastoma. SAGE. brain stem. CGAP. non-normalized. SAGE library method. cell line.36,prostate. carcinoma. cell line.14:25

prostate. normal. bulk.16prostate. carcinoma. bulk.17ovary. clear cell. poorly differentiated. carcinoma. CGAP. non-normalized. SAGE library method. cell line.40,prostate. carcinoma. cell line.14:18

prostate. normal. bulk.16prostate. carcinoma. bulk.17mammary gland. carcinoma. cell line. estrogen.71,prostate. carcinoma. cell line.14:24

prostate. normal. bulk.16prostate. carcinoma. cell line.18prostate. carcinoma. cell line.19,prostate. carcinoma. cell line.14:33

prostate. normal. bulk.16prostate. carcinoma. cell line.18brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30,prostate. carcinoma. cell line.14prostate. carcinoma. bulk.17:19

prostate. normal. bulk.16prostate. carcinoma. cell line.19brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30,prostate. carcinoma. cell line.14prostate. carcinoma. bulk.17prostate. carcinoma. cell line.18:18

prostate. normal. bulk.16brain. astrocytoma. bulk.27brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30,prostate. carcinoma. cell line.14prostate. carcinoma. cell line.15:21

prostate. normal. bulk.16brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30pancreas. epithelium. ductal. normal. cell line. CGAP. non-normalized. SAGE library method. cell line.41,prostate. carcinoma. cell line.15:21

prostate. normal. bulk.16brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30pancreas. epithelium. ductal. normal. cell line. CGAP. non-normalized. SAGE library method. cell line.44,prostate. carcinoma. cell line.15:22

prostate. normal. bulk.16brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30prostate. adenocarcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.47,prostate. carcinoma. cell line.15:19

prostate. normal. bulk.16brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30prostate. adenocarcinoma. microdissected. CGAP. non-normalized. SAGE library method. microdissected.67,prostate. carcinoma. cell line.14:17

prostate. normal. bulk.16medulloblastoma. SAGE. brain stem. CGAP. non-normalized. SAGE library method. cell line.36prostate. adenocarcinoma. microdissected. CGAP. non-normalized. SAGE library method. microdissected.67,prostate. carcinoma. cell line.14prostate. carcinoma. cell line.15:17

prostate. normal. bulk.16prostate. normal. microdissected. CGAP. non-normalized. SAGE library method. microdissected.66prostate. adenocarcinoma. microdissected. CGAP. non-normalized. SAGE library method. microdissected.67,prostate. carcinoma. cell line.14:17

prostate. normal. bulk.16prostate. adenocarcinoma. microdissected. CGAP. non-normalized. SAGE library method. microdissected.67mammary gland. carcinoma. cell line. estrogen.70,prostate. carcinoma. cell line.14:18

prostate. carcinoma. bulk.17prostate. carcinoma. cell line.19brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30,prostate. carcinoma. cell line.14prostate. normal. bulk.16prostate. carcinoma. cell line.18:18

prostate. carcinoma. bulk.17brain. astrocytoma. bulk.27brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30,prostate. carcinoma. cell line.15:18

prostate. carcinoma. bulk.17brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30pancreas. epithelium. ductal. normal. cell line. CGAP. non-normalized. SAGE library method. cell line.41,prostate. carcinoma. cell line.15:17

prostate. carcinoma. bulk.17brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30pancreas. epithelium. ductal. normal. cell line. CGAP. non-normalized. SAGE library method. cell line.44,prostate. carcinoma. cell line.15:18

prostate. carcinoma. bulk.17mammary gland. carcinoma. cell line.69mammary gland. carcinoma. cell line. estrogen.71,prostate. carcinoma. cell line.14:19

brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30pancreas. epithelium. ductal. normal. cell line. CGAP. non-normalized. SAGE library method. cell line.41prostate. adenocarcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.47,prostate. carcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.7brain. astrocytoma. bulk.27:17

brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30pancreas. epithelium. ductal. normal. cell line. CGAP. non-normalized. SAGE library method. cell line.44prostate. adenocarcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.47,brain. astrocytoma. bulk.27:19

ovary. epithelium. normal. bulk. CGAP. non-normalized. SAGE library method. cell line.43mammary gland. carcinoma. cell line. estrogen.70mammary gland. carcinoma. cell line. estrogen.71,mammary gland. carcinoma. cell line.69:19

prostate. normal. microdissected. CGAP. non-normalized. SAGE library method. microdissected.66mammary gland. carcinoma. cell line.69mammary gland. carcinoma. cell line. estrogen.71,mammary gland. carcinoma. cell line. estrogen.70:19

prostate. carcinoma. cell line.14prostate. carcinoma. cell line.15prostate. carcinoma. cell line.18prostate. carcinoma. cell line.19,prostate. normal. bulk.16:22

prostate. carcinoma. cell line.14prostate. carcinoma. bulk.17prostate. carcinoma. cell line.18brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30,prostate. normal. bulk.16:19

prostate. carcinoma. cell line.14prostate. carcinoma. bulk.17brain. astrocytoma. bulk.27brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30,prostate. carcinoma. cell line.15prostate. normal. bulk.16:17

prostate. carcinoma. cell line.14prostate. carcinoma. bulk.17brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30pancreas. epithelium. ductal. normal. cell line. CGAP. non-normalized. SAGE library method. cell line.44,prostate. carcinoma. cell line.15prostate. normal. bulk.16:17

prostate. carcinoma. cell line.14prostate. carcinoma. bulk.17medulloblastoma. SAGE. brain stem. CGAP. non-normalized. SAGE library method. cell line.36prostate. adenocarcinoma. microdissected. CGAP. non-normalized. SAGE library method. microdissected.67,prostate. carcinoma. cell line.15:18

prostate. carcinoma. cell line.15prostate. normal. bulk.16prostate. carcinoma. bulk.17pancreas. epithelium. ductal. normal. cell line. CGAP. non-normalized. SAGE library method. cell line.41,prostate. carcinoma. cell line.14:23

prostate. carcinoma. cell line.15prostate. normal. bulk.16prostate. carcinoma. bulk.17pancreas. epithelium. ductal. normal. cell line. CGAP. non-normalized. SAGE library method. cell line.44,prostate. carcinoma. cell line.14:21

prostate. carcinoma. cell line.15brain. astrocytoma. bulk.27brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30prostate. adenocarcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.47,prostate. carcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.7:20

prostate. carcinoma. cell line.15brain. astrocytoma. bulk.27pancreas. epithelium. ductal. normal. cell line. CGAP. non-normalized. SAGE library method. cell line.41prostate. adenocarcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.47,prostate. carcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.7:17

prostate. carcinoma. cell line.15brain. astrocytoma. bulk.27pancreas. epithelium. ductal. normal. cell line. CGAP. non-normalized. SAGE library method. cell line.44prostate. adenocarcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.47,prostate. carcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.7:20

prostate. carcinoma. cell line.15brain. medulloblastoma. cell line. CGAP. non-normalized. SAGE library method. cell line.30pancreas. epithelium. ductal. normal. cell line. CGAP. non-normalized. SAGE library method. cell line.44prostate. adenocarcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.47,brain. astrocytoma. bulk.27prostate. carcinoma. cell line. CGAP. non-normalized. SAGE library method. cell line.7:17

Feuil2

Feuil3

Feuil1

Ribosomal protein L37a22Human ribosomal protein L10 mRNA, complete cds623,Ribosomal protein L19364Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S2334960S RIBOSOMAL PROTEIN L18500ESTs631Ribosomal protein S26636Translation elongation factor 1 gamma757transcription elongation factor B (SIII), polypeptide 1-like763Translation elongation factor 1-alpha-1775:8

Ribosomal protein L37a22ESTs631,Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Human ribosomal protein L10 mRNA, complete cds623Ribosomal protein S26636Translation elongation factor 1 gamma757transcription elongation factor B (SIII), polypeptide 1-like763Translation elongation factor 1-alpha-1775:8

Ribosomal protein L3137ESTs631,Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Human ribosomal protein L10 mRNA, complete cds623Ribosomal protein S26636Translation elongation factor 1 gamma757transcription elongation factor B (SIII), polypeptide 1-like763Translation elongation factor 1-alpha-1775:8

60S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S23349,Ribosomal protein L37a22Ribosomal protein L313740S RIBOSOMAL PROTEIN S2151Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Human ribosomal protein L10 mRNA, complete cds623ESTs631Ribosomal protein S26636Translation elongation factor 1 gamma757transcription elongation factor B (SIII), polypeptide 1-like763Translation elongation factor 1-alpha-1775:8

40S RIBOSOMAL PROTEIN S2151transcription elongation factor B (SIII), polypeptide 1-like763,60S RIBOSOMAL PROTEIN L18500Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Ribosomal protein L37a22Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S23349Ribosomal protein L19364Human ribosomal protein L10 mRNA, complete cds623ESTs631Ribosomal protein S26636:8

Human ribosomal protein L10 mRNA, complete cds623Ribosomal protein S26636,Ribosomal protein L19364Ribosomal protein L37a22Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S2334960S RIBOSOMAL PROTEIN L18500ESTs631Translation elongation factor 1 gamma757transcription elongation factor B (SIII), polypeptide 1-like763Translation elongation factor 1-alpha-1775:8

Human ribosomal protein L10 mRNA, complete cds623transcription elongation factor B (SIII), polypeptide 1-like763,Ribosomal protein L19364Ribosomal protein L37a22Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S2334960S RIBOSOMAL PROTEIN L18500ESTs631Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775:8

ESTs631transcription elongation factor B (SIII), polypeptide 1-like763,Ribosomal protein L37a22Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Human ribosomal protein L10 mRNA, complete cds623Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775:8

transcription elongation factor B (SIII), polypeptide 1-like763Translation elongation factor 1-alpha-1775,Ribosomal protein L37a22Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Human ribosomal protein L10 mRNA, complete cds623ESTs631Ribosomal protein S26636Translation elongation factor 1 gamma757:8

Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S2151,Ribosomal protein L3137Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-177540S RIBOSOMAL PROTEIN S23349Human ribosomal protein L10 mRNA, complete cds623ESTs631transcription elongation factor B (SIII), polypeptide 1-like763:8

Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L23104Ribosomal protein L19364,Ribosomal protein L313740S RIBOSOMAL PROTEIN S215160S RIBOSOMAL PROTEIN L18500Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-177540S RIBOSOMAL PROTEIN S23349Human ribosomal protein L10 mRNA, complete cds623ESTs631Ribosomal protein S26636transcription elongation factor B (SIII), polypeptide 1-like763:8

Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L2310460S RIBOSOMAL PROTEIN L18500,Ribosomal protein L313740S RIBOSOMAL PROTEIN S2151Ribosomal protein L19364Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-177540S RIBOSOMAL PROTEIN S23349Human ribosomal protein L10 mRNA, complete cds623ESTs631transcription elongation factor B (SIII), polypeptide 1-like763:8

Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L23104Ribosomal protein S26636,Ribosomal protein L313740S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631transcription elongation factor B (SIII), polypeptide 1-like763:8

Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L23104Translation elongation factor 1 gamma757,Ribosomal protein L313740S RIBOSOMAL PROTEIN S2151Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Translation elongation factor 1-alpha-177540S RIBOSOMAL PROTEIN S23349Human ribosomal protein L10 mRNA, complete cds623ESTs631Ribosomal protein S26636transcription elongation factor B (SIII), polypeptide 1-like763:8

Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L23104Translation elongation factor 1-alpha-1775,Ribosomal protein L313740S RIBOSOMAL PROTEIN S2151Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Translation elongation factor 1 gamma75740S RIBOSOMAL PROTEIN S23349Human ribosomal protein L10 mRNA, complete cds623ESTs631Ribosomal protein S26636transcription elongation factor B (SIII), polypeptide 1-like763:8

Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S23349transcription elongation factor B (SIII), polypeptide 1-like763,Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S2151Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631:8

Ribosomal protein L37a22Ribosomal protein L19364transcription elongation factor B (SIII), polypeptide 1-like763,Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S2334960S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631:8

Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L18500transcription elongation factor B (SIII), polypeptide 1-like763,Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L19364Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631:8

Ribosomal protein L37a22Ribosomal protein S26636transcription elongation factor B (SIII), polypeptide 1-like763,Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631:8

Ribosomal protein L37a22Translation elongation factor 1 gamma757transcription elongation factor B (SIII), polypeptide 1-like763,Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631:8

Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S2151,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631transcription elongation factor B (SIII), polypeptide 1-like763:8

Ribosomal protein L313760S RIBOSOMAL PROTEIN L23104Ribosomal protein L19364,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S2334960S RIBOSOMAL PROTEIN L18500Translation elongation factor 1-alpha-177540S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623ESTs631Ribosomal protein S26636Translation elongation factor 1 gamma757transcription elongation factor B (SIII), polypeptide 1-like763:8

Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310460S RIBOSOMAL PROTEIN L18500,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S23349Ribosomal protein L19364Ribosomal protein S26636Translation elongation factor 1-alpha-177540S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623ESTs631Translation elongation factor 1 gamma757transcription elongation factor B (SIII), polypeptide 1-like763:8

Ribosomal protein L313760S RIBOSOMAL PROTEIN L23104Human ribosomal protein L10 mRNA, complete cds623,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Translation elongation factor 1-alpha-177540S RIBOSOMAL PROTEIN S2151ESTs631Ribosomal protein S26636Translation elongation factor 1 gamma757transcription elongation factor B (SIII), polypeptide 1-like763:8

Ribosomal protein L313760S RIBOSOMAL PROTEIN L23104Ribosomal protein S26636,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631transcription elongation factor B (SIII), polypeptide 1-like763:8

Ribosomal protein L313760S RIBOSOMAL PROTEIN L23104Translation elongation factor 1 gamma757,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631transcription elongation factor B (SIII), polypeptide 1-like763:8

Ribosomal protein L313760S RIBOSOMAL PROTEIN L23104Translation elongation factor 1-alpha-1775,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1 gamma757Human ribosomal protein L10 mRNA, complete cds623ESTs631transcription elongation factor B (SIII), polypeptide 1-like763:8

Ribosomal protein L313740S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500ESTs631Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-177560S RIBOSOMAL PROTEIN L23104transcription elongation factor B (SIII), polypeptide 1-like763:8

Ribosomal protein L313740S RIBOSOMAL PROTEIN S23349transcription elongation factor B (SIII), polypeptide 1-like763,Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L23104Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1 gamma75740S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623ESTs631Translation elongation factor 1-alpha-1775:8

Ribosomal protein L3137Ribosomal protein L19364transcription elongation factor B (SIII), polypeptide 1-like763,Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S2334960S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1 gamma75740S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623ESTs631Translation elongation factor 1-alpha-1775:8

Ribosomal protein L313760S RIBOSOMAL PROTEIN L18500transcription elongation factor B (SIII), polypeptide 1-like763,Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S23349Ribosomal protein L19364Ribosomal protein S26636Translation elongation factor 1 gamma75740S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623ESTs631Translation elongation factor 1-alpha-1775:8

Ribosomal protein L3137Human ribosomal protein L10 mRNA, complete cds623Translation elongation factor 1 gamma757,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500ESTs631Ribosomal protein S26636Translation elongation factor 1-alpha-177560S RIBOSOMAL PROTEIN L23104transcription elongation factor B (SIII), polypeptide 1-like763:8

Ribosomal protein L3137Human ribosomal protein L10 mRNA, complete cds623Translation elongation factor 1-alpha-1775,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1 gamma75760S RIBOSOMAL PROTEIN L23104ESTs631transcription elongation factor B (SIII), polypeptide 1-like763:8

Ribosomal protein L3137Ribosomal protein S26636transcription elongation factor B (SIII), polypeptide 1-like763,Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631:8

Ribosomal protein L3137Translation elongation factor 1 gamma757transcription elongation factor B (SIII), polypeptide 1-like763,Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631:8

60S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623,40S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500ESTs631Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Ribosomal protein L37a22Ribosomal protein L3137transcription elongation factor B (SIII), polypeptide 1-like763:8

60S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S2151ESTs631,40S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Human ribosomal protein L10 mRNA, complete cds623Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Ribosomal protein L37a22Ribosomal protein L3137transcription elongation factor B (SIII), polypeptide 1-like763:8

60S RIBOSOMAL PROTEIN L23104Ribosomal protein L19364transcription elongation factor B (SIII), polypeptide 1-like763,Ribosomal protein L37a22Ribosomal protein L313740S RIBOSOMAL PROTEIN S2334960S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-177540S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623ESTs631:8

60S RIBOSOMAL PROTEIN L2310460S RIBOSOMAL PROTEIN L18500Human ribosomal protein L10 mRNA, complete cds623,40S RIBOSOMAL PROTEIN S23349Ribosomal protein L19364Ribosomal protein S26636Translation elongation factor 1-alpha-1775Ribosomal protein L37a22Ribosomal protein L313740S RIBOSOMAL PROTEIN S2151ESTs631Translation elongation factor 1 gamma757transcription elongation factor B (SIII), polypeptide 1-like763:8

60S RIBOSOMAL PROTEIN L2310460S RIBOSOMAL PROTEIN L18500ESTs631,40S RIBOSOMAL PROTEIN S23349Ribosomal protein L19364Human ribosomal protein L10 mRNA, complete cds623Ribosomal protein S26636Translation elongation factor 1-alpha-1775Ribosomal protein L37a22Ribosomal protein L313740S RIBOSOMAL PROTEIN S2151Translation elongation factor 1 gamma757transcription elongation factor B (SIII), polypeptide 1-like763:8

60S RIBOSOMAL PROTEIN L2310460S RIBOSOMAL PROTEIN L18500transcription elongation factor B (SIII), polypeptide 1-like763,Ribosomal protein L37a22Ribosomal protein L313740S RIBOSOMAL PROTEIN S23349Ribosomal protein L19364Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-177540S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623ESTs631:8

60S RIBOSOMAL PROTEIN L23104Human ribosomal protein L10 mRNA, complete cds623Translation elongation factor 1 gamma757,40S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500ESTs631Translation elongation factor 1-alpha-1775Ribosomal protein L37a22Ribosomal protein L3137Ribosomal protein S26636transcription elongation factor B (SIII), polypeptide 1-like763:8

60S RIBOSOMAL PROTEIN L23104ESTs631Ribosomal protein S26636,Ribosomal protein L19364Human ribosomal protein L10 mRNA, complete cds623Translation elongation factor 1-alpha-1775Ribosomal protein L37a22Ribosomal protein L313740S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S2334960S RIBOSOMAL PROTEIN L18500Translation elongation factor 1 gamma757transcription elongation factor B (SIII), polypeptide 1-like763:8

60S RIBOSOMAL PROTEIN L23104ESTs631Translation elongation factor 1 gamma757,40S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Human ribosomal protein L10 mRNA, complete cds623Translation elongation factor 1-alpha-1775Ribosomal protein L37a22Ribosomal protein L313740S RIBOSOMAL PROTEIN S2151Ribosomal protein S26636transcription elongation factor B (SIII), polypeptide 1-like763:8

60S RIBOSOMAL PROTEIN L23104Ribosomal protein S26636transcription elongation factor B (SIII), polypeptide 1-like763,Ribosomal protein L37a22Ribosomal protein L313740S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Translation elongation factor 1 gamma75740S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623ESTs631Translation elongation factor 1-alpha-1775:8

60S RIBOSOMAL PROTEIN L23104Translation elongation factor 1 gamma757transcription elongation factor B (SIII), polypeptide 1-like763,Ribosomal protein L37a22Ribosomal protein L313740S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S2663640S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623ESTs631Translation elongation factor 1-alpha-1775:8

40S RIBOSOMAL PROTEIN S2151ESTs631Ribosomal protein S26636,40S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Human ribosomal protein L10 mRNA, complete cds623Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Ribosomal protein L37a22Ribosomal protein L313760S RIBOSOMAL PROTEIN L23104transcription elongation factor B (SIII), polypeptide 1-like763:8

Feuil2

Feuil3

Feuil1

Ribosomal protein L37a22Human ribosomal protein L10 mRNA, complete cds623,Ribosomal protein L19364Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S2334960S RIBOSOMAL PROTEIN L18500ESTs631Ribosomal protein S26636Translation elongation factor 1 gamma757ribosomal protein S18763Translation elongation factor 1-alpha-1775:8

Ribosomal protein L37a22ESTs631,Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Human ribosomal protein L10 mRNA, complete cds623Ribosomal protein S26636Translation elongation factor 1 gamma757ribosomal protein S18763Translation elongation factor 1-alpha-1775:8

Ribosomal protein L3137ESTs631,Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Human ribosomal protein L10 mRNA, complete cds623Ribosomal protein S26636Translation elongation factor 1 gamma757ribosomal protein S18763Translation elongation factor 1-alpha-1775:8

60S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S23349,Ribosomal protein L37a22Ribosomal protein L313740S RIBOSOMAL PROTEIN S2151Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Human ribosomal protein L10 mRNA, complete cds623ESTs631Ribosomal protein S26636Translation elongation factor 1 gamma757ribosomal protein S18763Translation elongation factor 1-alpha-1775:8

40S RIBOSOMAL PROTEIN S2151ribosomal protein S18763,60S RIBOSOMAL PROTEIN L18500Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Ribosomal protein L37a22Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S23349Ribosomal protein L19364Human ribosomal protein L10 mRNA, complete cds623ESTs631Ribosomal protein S26636:8

Human ribosomal protein L10 mRNA, complete cds623Ribosomal protein S26636,Ribosomal protein L19364Ribosomal protein L37a22Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S2334960S RIBOSOMAL PROTEIN L18500ESTs631Translation elongation factor 1 gamma757ribosomal protein S18763Translation elongation factor 1-alpha-1775:8

Human ribosomal protein L10 mRNA, complete cds623ribosomal protein S18763,Ribosomal protein L19364Ribosomal protein L37a22Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S2334960S RIBOSOMAL PROTEIN L18500ESTs631Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775:8

ESTs631ribosomal protein S18763,Ribosomal protein L37a22Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Human ribosomal protein L10 mRNA, complete cds623Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775:8

ribosomal protein S18763Translation elongation factor 1-alpha-1775,Ribosomal protein L37a22Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Human ribosomal protein L10 mRNA, complete cds623ESTs631Ribosomal protein S26636Translation elongation factor 1 gamma757:8

Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S2151,Ribosomal protein L3137Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-177540S RIBOSOMAL PROTEIN S23349Human ribosomal protein L10 mRNA, complete cds623ESTs631ribosomal protein S18763:8

Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L23104Ribosomal protein L19364,Ribosomal protein L313740S RIBOSOMAL PROTEIN S215160S RIBOSOMAL PROTEIN L18500Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-177540S RIBOSOMAL PROTEIN S23349Human ribosomal protein L10 mRNA, complete cds623ESTs631Ribosomal protein S26636ribosomal protein S18763:8

Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L2310460S RIBOSOMAL PROTEIN L18500,Ribosomal protein L313740S RIBOSOMAL PROTEIN S2151Ribosomal protein L19364Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-177540S RIBOSOMAL PROTEIN S23349Human ribosomal protein L10 mRNA, complete cds623ESTs631ribosomal protein S18763:8

Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L23104Ribosomal protein S26636,Ribosomal protein L313740S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631ribosomal protein S18763:8

Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L23104Translation elongation factor 1 gamma757,Ribosomal protein L313740S RIBOSOMAL PROTEIN S2151Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Translation elongation factor 1-alpha-177540S RIBOSOMAL PROTEIN S23349Human ribosomal protein L10 mRNA, complete cds623ESTs631Ribosomal protein S26636ribosomal protein S18763:8

Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L23104Translation elongation factor 1-alpha-1775,Ribosomal protein L313740S RIBOSOMAL PROTEIN S2151Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Translation elongation factor 1 gamma75740S RIBOSOMAL PROTEIN S23349Human ribosomal protein L10 mRNA, complete cds623ESTs631Ribosomal protein S26636ribosomal protein S18763:8

Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S23349ribosomal protein S18763,Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S2151Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631:8

Ribosomal protein L37a22Ribosomal protein L19364ribosomal protein S18763,Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S2334960S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631:8

Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L18500ribosomal protein S18763,Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L19364Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631:8

Ribosomal protein L37a22Ribosomal protein S26636ribosomal protein S18763,Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631:8

Ribosomal protein L37a22Translation elongation factor 1 gamma757ribosomal protein S18763,Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631:8

Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S2151,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631ribosomal protein S18763:8

Ribosomal protein L313760S RIBOSOMAL PROTEIN L23104Ribosomal protein L19364,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S2334960S RIBOSOMAL PROTEIN L18500Translation elongation factor 1-alpha-177540S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623ESTs631Ribosomal protein S26636Translation elongation factor 1 gamma757ribosomal protein S18763:8

Ribosomal protein L313760S RIBOSOMAL PROTEIN L2310460S RIBOSOMAL PROTEIN L18500,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S23349Ribosomal protein L19364Ribosomal protein S26636Translation elongation factor 1-alpha-177540S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623ESTs631Translation elongation factor 1 gamma757ribosomal protein S18763:8

Ribosomal protein L313760S RIBOSOMAL PROTEIN L23104Human ribosomal protein L10 mRNA, complete cds623,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Translation elongation factor 1-alpha-177540S RIBOSOMAL PROTEIN S2151ESTs631Ribosomal protein S26636Translation elongation factor 1 gamma757ribosomal protein S18763:8

Ribosomal protein L313760S RIBOSOMAL PROTEIN L23104Ribosomal protein S26636,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631ribosomal protein S18763:8

Ribosomal protein L313760S RIBOSOMAL PROTEIN L23104Translation elongation factor 1 gamma757,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631ribosomal protein S18763:8

Ribosomal protein L313760S RIBOSOMAL PROTEIN L23104Translation elongation factor 1-alpha-1775,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1 gamma757Human ribosomal protein L10 mRNA, complete cds623ESTs631ribosomal protein S18763:8

Ribosomal protein L313740S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500ESTs631Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-177560S RIBOSOMAL PROTEIN L23104ribosomal protein S18763:8

Ribosomal protein L313740S RIBOSOMAL PROTEIN S23349ribosomal protein S18763,Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L23104Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1 gamma75740S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623ESTs631Translation elongation factor 1-alpha-1775:8

Ribosomal protein L3137Ribosomal protein L19364ribosomal protein S18763,Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S2334960S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1 gamma75740S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623ESTs631Translation elongation factor 1-alpha-1775:8

Ribosomal protein L313760S RIBOSOMAL PROTEIN L18500ribosomal protein S18763,Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S23349Ribosomal protein L19364Ribosomal protein S26636Translation elongation factor 1 gamma75740S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623ESTs631Translation elongation factor 1-alpha-1775:8

Ribosomal protein L3137Human ribosomal protein L10 mRNA, complete cds623Translation elongation factor 1 gamma757,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500ESTs631Ribosomal protein S26636Translation elongation factor 1-alpha-177560S RIBOSOMAL PROTEIN L23104ribosomal protein S18763:8

Ribosomal protein L3137Human ribosomal protein L10 mRNA, complete cds623Translation elongation factor 1-alpha-1775,Ribosomal protein L37a2240S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1 gamma75760S RIBOSOMAL PROTEIN L23104ESTs631ribosomal protein S18763:8

Ribosomal protein L3137Ribosomal protein S26636ribosomal protein S18763,Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631:8

Ribosomal protein L3137Translation elongation factor 1 gamma757ribosomal protein S18763,Ribosomal protein L37a2260S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1-alpha-1775Human ribosomal protein L10 mRNA, complete cds623ESTs631:8

60S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623,40S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500ESTs631Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Ribosomal protein L37a22Ribosomal protein L3137ribosomal protein S18763:8

60S RIBOSOMAL PROTEIN L2310440S RIBOSOMAL PROTEIN S2151ESTs631,40S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Human ribosomal protein L10 mRNA, complete cds623Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Ribosomal protein L37a22Ribosomal protein L3137ribosomal protein S18763:8

60S RIBOSOMAL PROTEIN L23104Ribosomal protein L19364ribosomal protein S18763,Ribosomal protein L37a22Ribosomal protein L313740S RIBOSOMAL PROTEIN S2334960S RIBOSOMAL PROTEIN L18500Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-177540S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623ESTs631:8

60S RIBOSOMAL PROTEIN L2310460S RIBOSOMAL PROTEIN L18500Human ribosomal protein L10 mRNA, complete cds623,40S RIBOSOMAL PROTEIN S23349Ribosomal protein L19364Ribosomal protein S26636Translation elongation factor 1-alpha-1775Ribosomal protein L37a22Ribosomal protein L313740S RIBOSOMAL PROTEIN S2151ESTs631Translation elongation factor 1 gamma757ribosomal protein S18763:8

60S RIBOSOMAL PROTEIN L2310460S RIBOSOMAL PROTEIN L18500ESTs631,40S RIBOSOMAL PROTEIN S23349Ribosomal protein L19364Human ribosomal protein L10 mRNA, complete cds623Ribosomal protein S26636Translation elongation factor 1-alpha-1775Ribosomal protein L37a22Ribosomal protein L313740S RIBOSOMAL PROTEIN S2151Translation elongation factor 1 gamma757ribosomal protein S18763:8

60S RIBOSOMAL PROTEIN L2310460S RIBOSOMAL PROTEIN L18500ribosomal protein S18763,Ribosomal protein L37a22Ribosomal protein L313740S RIBOSOMAL PROTEIN S23349Ribosomal protein L19364Ribosomal protein S26636Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-177540S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623ESTs631:8

60S RIBOSOMAL PROTEIN L23104Human ribosomal protein L10 mRNA, complete cds623Translation elongation factor 1 gamma757,40S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500ESTs631Translation elongation factor 1-alpha-1775Ribosomal protein L37a22Ribosomal protein L3137Ribosomal protein S26636ribosomal protein S18763:8

60S RIBOSOMAL PROTEIN L23104ESTs631Ribosomal protein S26636,Ribosomal protein L19364Human ribosomal protein L10 mRNA, complete cds623Translation elongation factor 1-alpha-1775Ribosomal protein L37a22Ribosomal protein L313740S RIBOSOMAL PROTEIN S215140S RIBOSOMAL PROTEIN S2334960S RIBOSOMAL PROTEIN L18500Translation elongation factor 1 gamma757ribosomal protein S18763:8

60S RIBOSOMAL PROTEIN L23104ESTs631Translation elongation factor 1 gamma757,40S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Human ribosomal protein L10 mRNA, complete cds623Translation elongation factor 1-alpha-1775Ribosomal protein L37a22Ribosomal protein L313740S RIBOSOMAL PROTEIN S2151Ribosomal protein S26636ribosomal protein S18763:8

60S RIBOSOMAL PROTEIN L23104Ribosomal protein S26636ribosomal protein S18763,Ribosomal protein L37a22Ribosomal protein L313740S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Translation elongation factor 1 gamma75740S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623ESTs631Translation elongation factor 1-alpha-1775:8

60S RIBOSOMAL PROTEIN L23104Translation elongation factor 1 gamma757ribosomal protein S18763,Ribosomal protein L37a22Ribosomal protein L313740S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Ribosomal protein S2663640S RIBOSOMAL PROTEIN S2151Human ribosomal protein L10 mRNA, complete cds623ESTs631Translation elongation factor 1-alpha-1775:8

40S RIBOSOMAL PROTEIN S2151ESTs631Ribosomal protein S26636,40S RIBOSOMAL PROTEIN S23349Ribosomal protein L1936460S RIBOSOMAL PROTEIN L18500Human ribosomal protein L10 mRNA, complete cds623Translation elongation factor 1 gamma757Translation elongation factor 1-alpha-1775Ribosomal protein L37a22Ribosomal protein L313760S RIBOSOMAL PROTEIN L23104ribosomal protein S18763:8

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Extraction de rgles biologiquement stimulantes :

Extraction de rgles dassociation (4/6)

Extraction de rgles dassociation (5/6)Extraction sur la matrice 90x27679 : lalgorithme atteint ses limites

Extraction de rgles dassociation (6/6)Solution envisage (GREYC) :Transposition de la matriceExtraction sur les situations biologiquesPassage par la connexion de Galois pour extraire des concepts

Le contexte permet lextraction des concepts laide de nos extracteurs (Ac-miner ; Mv-miner)

La notion de concept (1/4)Un concept est un groupe reliant deux ensembles :un ensemble de gnesun ensemble de librairiesExemple : 4 gnes surexprims dans 4 librairies.

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concept672 :

Librairies8_brain bulk10_brain bulk41_thalamus bulk85_brain bulk

GnesHs.82071651Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2CITED2

Hs.182825717ribosomal protein L35RPL35

Hs.306738813Sapiens cDNA: FLJ21341 fis, clone COL02653.

Hs.75106946clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J)CLU

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La notion de concept (2/4)Connexion de Galois:Formalisme mathmatique qui rend compte des relations dcrites par la matrice binaire

Soit L = ensemble des librairies , T = ensemble des tags2 fonctions :f : L T g : T L

La notion de concept (3/4)Ensemble ferm :Soit l un ensemble de librairies et t un ensemble de tags.l est ferm ssi gof(l) = g(f(l)) = l.t est ferm ssi fog(t) = f(g(t)) = t.Concept = paire (l,t) tel que : f(l)=t et g(t) = lO l et t sont des ferms t.q. gof (l) = l.

La notion de concept (4/4)Concrtement :f et g :f({L1}) = {B,C,E}f({L1,L3,L4}) = {B,C}g({A}) = {L4}g({B,C}) = {L1,L3,L4}

Ferms :g(f({L1})) = g({B,C,E}) = {L1}g(f({L1,L3}) = g({B,C}) = {L1,L3,L4} Concepts de cette matrice :({L1}, {B,C,E}) ; ({L3}, {B,C,D}) ; ({L4}, {A,B,C}) ;({L2,L3}, {D}) ; ({L1,L3,L4}, {B,C}) ;

Extraction de concepts (1/2)A partir des ensembles libres on peut calculer lensemble des ferms.Notre stratgie : pour calculer lensemble des concepts, on calcule tous les libres sur la matrice transposeon calcule alors leur fermetureon en dduit les concepts

Extraction de concepts (2/2)Conclusion :On rgle un verrou technologique

et on obtient une nouvelle information biologiquement intressante : le lien entre des groupes de gnes et des situations biologiques qui les surexpriment (Rioult et al, KDID03)

Exploration des donnes : techniques inductivesSchma classique :

2 post traitements :Slection des concepts dintrtOutil de visualisation

PostTraitement (1/3)Ncessit dinterroger une collection de concepts1er outil : slection de concepts dintrt4 critres :Homognit des librairies (ex : carcinoma)Prsence dun ensemble de gnes dintrtNombre de librairies dans le conceptNombre de tags dans le conceptPossibilit de les combiner (conjonction)

PostTraitement (2/3)Loutil de slection permet de diminuer drastiquement le nombre de concepts analyser

PostTraitement (3/3)2me outil : outil de visualisation des concepts (Ruggero Pensa et Cline Robardet)Classification hirarchique des conceptsPiste extrmement prometteuse car classification dinteractions entre les objets que lon tudie

Interprtation biologi