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Gwaith bob dydd malu rhifau i greu gwybodaeth newydd am effaith The day job - number crunching new knowledge for impact 8 Mawrth 2018 8 March 2018 Dr Dyfed Wyn Huws Cyfarwyddwr Uned Gwybodaeth a Gwyliadwriaeth Canser Cymru Director Welsh Cancer Intelligence and Surveillance Unit

Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

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Page 1: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

Gwaith bob dydd – malu rhifau i greugwybodaeth newydd am effaith

The day job - number crunching new knowledge for impact

8 Mawrth 2018 8 March 2018

Dr Dyfed Wyn Huws

Cyfarwyddwr Uned Gwybodaeth a Gwyliadwriaeth Canser Cymru

Director Welsh Cancer Intelligence and Surveillance Unit

Page 2: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

Public Health Wales - Public health research, policy and practice: research with impact 2018

• To undertake the systematic collection, analysis and dissemination of information about the health of the people of Wales in particular including cancer incidence, mortality and survival

Welsh Cancer Intelligence and Surveillance Unit - the day job

One of four Public Health Wales statutory functions

Page 3: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

Public Health Wales - Public health research, policy and practice: research with impact 2018

Page 4: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

Public Health Wales - Public health research, policy and practice: research with impact 2018

Page 5: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

Incidence and mortality rate at small area levelAll cancers excluding non melanoma skin cancer

Incidence, 2011-2015

©Crown Copyright and database right 2016. Ordnance Survey 100044810

Mortality, 2010-2014

Public Health Wales - Public health research, policy and practice: research with impact 2018

Page 6: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

NHS Health

Research

Authority

definitions

of research

and more

Public Health Wales - Public health research, policy and practice: research with impact 2018

Page 7: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

Public Health Wales - Public health research, policy and practice: research with impact 2018

Page 8: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

Public Health Wales - Public health research, policy and practice: research with impact 2018

Page 9: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

• Shubhangi Govil, School of Medicine, Cardiff University.

• Kate Lifford, Sunil Dolwani, Division of Population Medicine, School of Medicine, Cardiff University.

• Hayley Heard, Bowel Screening Wales, Public Health Wales.

• Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales.

The impact of the Welsh bowel screening programme on emergency presentation for colorectal cancer.

Public Health Wales - Public health research, policy and practice: research with impact 2018

Page 10: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

Incidence rate for deprivation fifths by cancer type

Source: Welsh Cancer Intelligence and Surveillance Unit’s Cancer Registry www.wcisu.wales.nhs.uk

Gap has narrowed

Gap has widened

Lung cancer incidence most deprived

Lung cancer incidence least deprived

Public Health Wales - Public health research, policy and practice: research with impact 2018

Page 11: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

Public Health Wales - Public health research, policy and practice: research with impact 2018

Page 12: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

8.78.7

9.810.410.711.011.711.711.912.413.213.5

15.515.715.8

17.919.219.2

20.522.3

24.524.825.425.925.9

26.927.527.627.827.9

29.731.1

32.938.138.5

40.443.0

44.545.3

46.554.9

0.0 10.0 20.0 30.0 40.0 50.0 60.0

UkraineBelarus

Russian FederationLithuania

CyprusMaltaLatvia

PortugalMoldovaBulgariaGreeceEstonia

Bosnia HerzegovinaSpain

RomaniaFinland

ItalyFYR Macedonia

SlovakiaCroatiaAlbania

SloveniaGermany

Czech RepublicMontenegroLuxembourg

SwedenBelgiumAustriaFrance

SwitzerlandPolandSerbia

NorwayUnited Kingdom

IrelandIceland

The NetherlandsWales

HungaryDenmark

EASR per 100,000 population

EASR per 100,000 population calculated using the 1976 European standard population. Source: J. Ferlay, E. Steliarova-Foucher, J. Lortet-Tieulent, S. Rosso, J.W.W. Coebergh, H. Comber, D. Forman, F. Bray. European Journal of Cancer. Volume 49, Issue 6, Pages 1374-1403 (April 2013) DOI: 10.1016/j.ejca.2012.12.027. Copyright © 2013 Elsevier

Lung cancer incidence in Europe, women: Estimates, 2012

Public Health Wales - Public health research, policy and practice: research with impact 2018

Page 13: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

Lung cancer in Wales

Variation in stage distribution between ICBP-1 jurisdictions

Slide thanks toDr Mick Peake

Page 14: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

Concord 3 study – 5 year age standardised net survival, lung cancer, 2010-2014

7.7

9.9

10.0

10.6

11.1

11.2

12.0

12.7

12.9

13.0

13.4

13.5

13.7

14.4

14.8

14.9

15.7

15.9

16.6

16.9

17.3

17.3

17.5

18.2

18.3

19.0

19.4

19.5

19.7

20.2

20.4

20.4

20.6

Bulgaria

Lithuania

Croatia

Czech Republic

Romania

Slovakia

Wales

Northern Ireland

Scotland

Finland

England

Spain

Russian Federation

Poland

Slovenia

Malta

Portugal

Italy

Denmark

Estonia

France

Netherlands

Ireland

Belgium

Germany

Norway

Australia

Sweden

Austria

Iceland

Latvia

Switzerland

Canada

5 year age standardised net survival (%) for lung cancer 2010-2014

Public Health Wales - Public health research, policy and practice: research with impact 2018

Page 15: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

• 1. North Wales Centre for Primary Care Research, Bangor University

• 2. Academic Unit of Primary Care, Leeds Institute of Health Sciences, University of Leeds

• 3. Welsh Cancer Intelligence and Surveillance Unit (WCISU), Health Intelligence Division, Public Health Wales

• 4. Hywel Dda University Health Board

Factors associated with lung cancer survival – systematic mapping review and overview of systematic reviews

Ruth Lewis,1 Maggie Hendry,1 Nafees Din,1 Marion A Stanciu,1

Sadia Nafees,1 Annie Hendry,1 Zhi Teoh,1 Thomas Lloyd,1 Rachel Parsonage,1 Richard D Neal,2 Gareth Collier,3 Dyfed W Huws

Public Health Wales - Public health research, policy and practice: research with impact 2018

Page 16: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

Figure 9: Surgery in patients with NSCLC: Proportion and adjusted odds ratio* by age

*p<0.0001. 95% CIs = 95% Confidence Interval.

AORs have been adjusted for diagnosis year, gender, age, performance status and tumour stage. Age <65 was the reference category.

Public Health Wales - Public health research, policy and practice: research with impact 2018

Page 17: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

What is the International Cancer Benchmarking

Partnership?

ICBP impacts

Public Health Wales - Public health research, policy and practice: research with impact 2018

Page 18: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

Public Health Wales - Public health research, policy and practice: research with impact 2018

Page 19: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

• Amy Downing, Penny Wright, Luke Hounsome, Paul Kind, Peter J Selby, Sarah Wilding, David Donnelly, Hugh Butcher, Eila Watson, Richard Wagland, Dyfed Huws, David Brewster, Anna Gavin, Adam Glaser on behalf of the LAPCD study team.

Life After Prostate Cancer Diagnosis: A UK-wide population-based health-related quality of life outcomes study

Public Health Wales - Public health research, policy and practice: research with impact 2018

Page 20: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

The fraction of cancer attributable to modifiable risk factors in

England, Wales, Scotland, Northern Ireland, and the United Kingdom

in 2015

KF Brown1*, H Rumgay1, C Dunlop1, M Ryan1, F Quartly1, A Cox1, A

Deas2, L Elliss-Brookes3, A Gavin4, L Hounsome3, D Huws5, N Ormiston-

Smith1, J Shelton1, C White5, DM Parkin6.

Public Health Wales - Public health research, policy and practice: research with impact 2018

Page 21: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

Public Health Wales - Public health research, policy and practice: research with impact 2018

Page 22: Gwaith bob dydd malu rhifau i greu gwybodaeth …€¦ · •Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales. The impact of the Welsh

Asking questions, providing answersResearch skills

Info governanceEthics

GrantsAcademic experience

New methods, data scienceBig data

Embedding as routineSharing data

Radiotherapy

Dataset

National

Cancer

Screening

Dataset

Primary care

(GP)

Dataset

Canisc

MDTs Clinical

Datasets

Clinical Trials

(NISCHR)

Dataset

Palliative

Care Dataset

Wales Cancer

Bank Dataset

Cancer

Genetics

Dataset

Cancer Data

Repository

WCISU

(Registry)

Dataset

SACT

Dataset

PEDW

(Admitted

Patient Care

Datasets)

Chronic

Conditions &

Rehabilitation

Dataset

Public Health Wales - Public health research, policy and practice: research with impact 2018