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Gwaith bob dydd – malu rhifau i greugwybodaeth newydd am effaith
The day job - number crunching new knowledge for impact
8 Mawrth 2018 8 March 2018
Dr Dyfed Wyn Huws
Cyfarwyddwr Uned Gwybodaeth a Gwyliadwriaeth Canser Cymru
Director Welsh Cancer Intelligence and Surveillance Unit
Public Health Wales - Public health research, policy and practice: research with impact 2018
• To undertake the systematic collection, analysis and dissemination of information about the health of the people of Wales in particular including cancer incidence, mortality and survival
Welsh Cancer Intelligence and Surveillance Unit - the day job
One of four Public Health Wales statutory functions
Public Health Wales - Public health research, policy and practice: research with impact 2018
Public Health Wales - Public health research, policy and practice: research with impact 2018
Incidence and mortality rate at small area levelAll cancers excluding non melanoma skin cancer
Incidence, 2011-2015
©Crown Copyright and database right 2016. Ordnance Survey 100044810
Mortality, 2010-2014
Public Health Wales - Public health research, policy and practice: research with impact 2018
NHS Health
Research
Authority
definitions
of research
and more
Public Health Wales - Public health research, policy and practice: research with impact 2018
Public Health Wales - Public health research, policy and practice: research with impact 2018
Public Health Wales - Public health research, policy and practice: research with impact 2018
• Shubhangi Govil, School of Medicine, Cardiff University.
• Kate Lifford, Sunil Dolwani, Division of Population Medicine, School of Medicine, Cardiff University.
• Hayley Heard, Bowel Screening Wales, Public Health Wales.
• Ceri White, Dyfed Huws, Wales Cancer Intelligence and Surveillance Unit, Public Health Wales.
The impact of the Welsh bowel screening programme on emergency presentation for colorectal cancer.
Public Health Wales - Public health research, policy and practice: research with impact 2018
Incidence rate for deprivation fifths by cancer type
Source: Welsh Cancer Intelligence and Surveillance Unit’s Cancer Registry www.wcisu.wales.nhs.uk
Gap has narrowed
Gap has widened
Lung cancer incidence most deprived
Lung cancer incidence least deprived
Public Health Wales - Public health research, policy and practice: research with impact 2018
Public Health Wales - Public health research, policy and practice: research with impact 2018
8.78.7
9.810.410.711.011.711.711.912.413.213.5
15.515.715.8
17.919.219.2
20.522.3
24.524.825.425.925.9
26.927.527.627.827.9
29.731.1
32.938.138.5
40.443.0
44.545.3
46.554.9
0.0 10.0 20.0 30.0 40.0 50.0 60.0
UkraineBelarus
Russian FederationLithuania
CyprusMaltaLatvia
PortugalMoldovaBulgariaGreeceEstonia
Bosnia HerzegovinaSpain
RomaniaFinland
ItalyFYR Macedonia
SlovakiaCroatiaAlbania
SloveniaGermany
Czech RepublicMontenegroLuxembourg
SwedenBelgiumAustriaFrance
SwitzerlandPolandSerbia
NorwayUnited Kingdom
IrelandIceland
The NetherlandsWales
HungaryDenmark
EASR per 100,000 population
EASR per 100,000 population calculated using the 1976 European standard population. Source: J. Ferlay, E. Steliarova-Foucher, J. Lortet-Tieulent, S. Rosso, J.W.W. Coebergh, H. Comber, D. Forman, F. Bray. European Journal of Cancer. Volume 49, Issue 6, Pages 1374-1403 (April 2013) DOI: 10.1016/j.ejca.2012.12.027. Copyright © 2013 Elsevier
Lung cancer incidence in Europe, women: Estimates, 2012
Public Health Wales - Public health research, policy and practice: research with impact 2018
Lung cancer in Wales
Variation in stage distribution between ICBP-1 jurisdictions
Slide thanks toDr Mick Peake
Concord 3 study – 5 year age standardised net survival, lung cancer, 2010-2014
7.7
9.9
10.0
10.6
11.1
11.2
12.0
12.7
12.9
13.0
13.4
13.5
13.7
14.4
14.8
14.9
15.7
15.9
16.6
16.9
17.3
17.3
17.5
18.2
18.3
19.0
19.4
19.5
19.7
20.2
20.4
20.4
20.6
Bulgaria
Lithuania
Croatia
Czech Republic
Romania
Slovakia
Wales
Northern Ireland
Scotland
Finland
England
Spain
Russian Federation
Poland
Slovenia
Malta
Portugal
Italy
Denmark
Estonia
France
Netherlands
Ireland
Belgium
Germany
Norway
Australia
Sweden
Austria
Iceland
Latvia
Switzerland
Canada
5 year age standardised net survival (%) for lung cancer 2010-2014
Public Health Wales - Public health research, policy and practice: research with impact 2018
• 1. North Wales Centre for Primary Care Research, Bangor University
• 2. Academic Unit of Primary Care, Leeds Institute of Health Sciences, University of Leeds
• 3. Welsh Cancer Intelligence and Surveillance Unit (WCISU), Health Intelligence Division, Public Health Wales
• 4. Hywel Dda University Health Board
Factors associated with lung cancer survival – systematic mapping review and overview of systematic reviews
Ruth Lewis,1 Maggie Hendry,1 Nafees Din,1 Marion A Stanciu,1
Sadia Nafees,1 Annie Hendry,1 Zhi Teoh,1 Thomas Lloyd,1 Rachel Parsonage,1 Richard D Neal,2 Gareth Collier,3 Dyfed W Huws
Public Health Wales - Public health research, policy and practice: research with impact 2018
Figure 9: Surgery in patients with NSCLC: Proportion and adjusted odds ratio* by age
*p<0.0001. 95% CIs = 95% Confidence Interval.
AORs have been adjusted for diagnosis year, gender, age, performance status and tumour stage. Age <65 was the reference category.
Public Health Wales - Public health research, policy and practice: research with impact 2018
What is the International Cancer Benchmarking
Partnership?
ICBP impacts
Public Health Wales - Public health research, policy and practice: research with impact 2018
Public Health Wales - Public health research, policy and practice: research with impact 2018
• Amy Downing, Penny Wright, Luke Hounsome, Paul Kind, Peter J Selby, Sarah Wilding, David Donnelly, Hugh Butcher, Eila Watson, Richard Wagland, Dyfed Huws, David Brewster, Anna Gavin, Adam Glaser on behalf of the LAPCD study team.
Life After Prostate Cancer Diagnosis: A UK-wide population-based health-related quality of life outcomes study
Public Health Wales - Public health research, policy and practice: research with impact 2018
The fraction of cancer attributable to modifiable risk factors in
England, Wales, Scotland, Northern Ireland, and the United Kingdom
in 2015
KF Brown1*, H Rumgay1, C Dunlop1, M Ryan1, F Quartly1, A Cox1, A
Deas2, L Elliss-Brookes3, A Gavin4, L Hounsome3, D Huws5, N Ormiston-
Smith1, J Shelton1, C White5, DM Parkin6.
Public Health Wales - Public health research, policy and practice: research with impact 2018
Public Health Wales - Public health research, policy and practice: research with impact 2018
Asking questions, providing answersResearch skills
Info governanceEthics
GrantsAcademic experience
New methods, data scienceBig data
Embedding as routineSharing data
Radiotherapy
Dataset
National
Cancer
Screening
Dataset
Primary care
(GP)
Dataset
Canisc
MDTs Clinical
Datasets
Clinical Trials
(NISCHR)
Dataset
Palliative
Care Dataset
Wales Cancer
Bank Dataset
Cancer
Genetics
Dataset
Cancer Data
Repository
WCISU
(Registry)
Dataset
SACT
Dataset
PEDW
(Admitted
Patient Care
Datasets)
Chronic
Conditions &
Rehabilitation
Dataset
Public Health Wales - Public health research, policy and practice: research with impact 2018