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LAPORAN AKTIVITI 2014

PUSAT PERKHIDMATAN DAN

PENYELIDIKAN NEUROSAINS

(P3NEURO)

1

BIDANG SPESIFIK BIDANG PENYELIDIK PERUNTUKAN (KPT)

PERUNTUKAN (USM)

JUMLAH

Fundamental Neuroscience

Neurobehaviour 1002.CNEURO.910114

Dr Muzaimi Mustapha

RM200,000 RM200,000

Blood Brain Behaviour 304.CNEURO.652202.

K134

Dr Siti Rafidah Yusof

RM250,000 RM150,000 RM400,000

Neurobehaviour 304.CNEURO.652201.

K134

Dr Zurina Hassan

RM250,000 RM150,000 RM400,000

Neurocognitive Sciences (304.CNEURO.652204.K134)

Brain-based learning (focusing on children with

learning difficulties)

Prof. Zalina Ismail

RM500,000 RM200,000 RM700,000

Neuro-imaging

(304.CNEURO.652203.K134)

Imaging Biomarkers for Neurological Diseases

Prof. Mandava Rajeswari

RM500,000 RM50,000 RM550,000

Neurology & Psychiatry

(304.PPSP.652205.K134)

Neurology (Adult,Pediatric)/

Psychiatry

Prof. Zabidi 500,000.00 200,000.00 700,000.00

Neurosurgeri

(1002.CNEURO.910116)

Equipment Prof. Jafri Malin

1,000 000.00 1,000 000.00

Pentadbiran/Pengurusan

(1002.CNEURO.910116 )

Steering Committee Prof. Jafri Malin

50,000.00 50,000.00

JUMLAH 2,000 000.00 4,000 000.00

GERAN PENYELIDIKAN DI BAWAH P3NEURO

- PERUNTUKAN KPT & USM ~

2

TAJUK PENYELIDIK JENIS GERAN JUMLAH

Effects of chronic hypoxia on Semaphorin class 3 expression in human

hippocampal neurons and astrocytes

(203/CNEURO/6171168)

Prof.Dato’ Dr Jafri Malin Abdullah

Skim Geran Penyelidikan

Fundamental(FRGS)

RM140,500

Time Dependent Changes of Morphology and

Molecular Charaterization Around the

Intracerebellar Hemorrhage (ICbH)

Penumbra in C57B6/J Mice Brain Slices

(305/CNEURO/6113609)

Prof.Dato’ Dr Jafri Malin Abdullah

Sciencefund

RM126,000

GERAN PENYELIDIKAN DI BAWAH P3NEURO

- PERUNTUKAN USM & SCIENCEFUND~

3

BIL PROGRAM STATUS

1.

Society For Brain Mapping And Therapeutics USA(President Barack Obama/G20 Brain

Initiative Project)

Ogos 2014

2.

Non-Disclosure Agreement Between Usm &

Danmedik Sdn.Bhd & University Teknology

Petronas

Sep 2014

3.

Mou Among Usm, Utp, Chulalongkorn University And Cuban Neuroscience Center In Neuroinformatics And Cognitive Neuroscience

Julai 2014

4.

Research Collaboration Agreement Between Usm & Cuban Neurosciences Center In

Neuroinformatiics

April 2014

5.

Non-Disclosure Agreement Between Usm & Biotropics Malaysia Berhad For Memory

Compound Clinical Trail

April 2014

6.

Mou Usm & Georg August University Gottingen, Germany General Neurosciences

Mac 2014

7.

Extended Research Collaboration Between Usm & Institute Of Technology Petronas High Data

Storage

Mei 2014

MOU/MOA/NDA

4

BIL PROGRAM TARIKH

1. Penganjuran 14th NAM Annual Scientific & General Meeting Featuring Awake Craniotomy Live Surgery by Assoc. Prof Dr Zamzuri Idris

15-17 Ogos 2014

2. Perbincangan ‘Art and Dance Teraphy Programme School of Arts USM’ bersama YBhg.Prof. Emeritus Dr. Mohamed Ghouse Nasuruddin’ dan ‘new Rehab Service:Art and Dance Teraphy’ at HUSM 2014

7 Januari 2014

3. Perbincangan untuk ‘Long Terms Research Grants(LRGS)

project bersama UTP, UIAM,UUM, UITM,UTM, University

Nottingham Malaysia

19 Januari 2014

4. Perbincangan bersama Biotropics Malaysia Berhad untuk

kolaborasi masa hadapan berkaitan ‘potential of clinical

studies’

28 Januari 2014

5. Perbincangan bersama Bahagian Pendidikan Menengah , MARA untuk penubuhan Kelab Neurosains di setiap MRSM

19 Februari 2014

6. Penganjuran ‘Lunch Talk’ oleh Azali Azlan, pelajar terbaik

SPM2007

7 September 2014

7. Mesyuarat bersama syarikat Danmedik Sdn. Bhd bagi projek Green Lane

2 Oktober 2014

8. Lawatan daripada Khazanah Nasional bagi tajaan biasiswa pelajar

19 Oktober 2014

9. Perjumpaan Bersama Kedutaan Bosnia Herzegovina, Mr. Tariq Bukric bagi perbincangan peluang melanjutkan pengajian di USM

14 November 2014

10. Perbincangan Penyelidikan Neuroinformatik bersama UTM

30 Januari 2014

LATIHAN/KOLABORASI

5

BIL TAJUK

1.

Two Novel Gross Deletions of TSC2 in Malaysian Patients with Tuberous Sclerosis Complex and TSC2/PKD1 Contiguous Deletion Syndrome;Japanese Journal of Clinical Oncology Advance Access; Nur Farah Dila Ismail, Nik Mohd Ariff Nik Abdul Malik. Jafar Mohseni, Abdulqawee Mahyoob Rani, Fatemeh Hayati, Abdul Razak Salmi; Mohd Yusof Narazah, Z.A.M.H. Zabidi-Hussin, Abdul Rashid Silawati, Wee Teik Keng, Lock Hock Ngu and Teguh Haryo Sasongko; Jpn. J. Clin. Oncol. (2014) doi: 10.1093/jjco/hyu024 First published online: March 30, 2014

2. In Vitro models of blood-brain barriers, in Drug Delivery to the Brain, Physiological Concepts, Methodologies and Approaches, Hammarlund-Udenaes M,N Joan Abbott, Diana EM Dolman, Siti R Yusof, Andreas Reichel, de Lange E, Thorne R (eds.), Vol.10,pp.163-197, Springer New York;2014

3. Microgravity environment and compensatory: Decompensatory phases for intracranial hypertensio

n form new perspectivesto explain mechanism underlying communicating hydrocephalus and

its related disorders. Idris Z, Mustapha M, Abdullah JM.

Asian J Neurosurg. 2014 Jan;9(1):7-13. doi: 10.4103/1793-5482.131058

4. Future Aspects of Clinical Applications using EEG and fMRI-EEG; Zamzuri Idris. Author: EEG

Chapter. 2013: Accepted for publication in 2014

5. Fibromyalgia and arachnoiditis presented as an acute spinal disorder; Zamzuri Idris, Faizul H. Ghazali, Jafri M. Abdullah,; Surgical Neurology International,An Open Access, International Journal of Neurosurgery and Neuroscience , 2014/Vol 5/Issue 1; ISSN:2229-5097

6. Principles, Anatomical Origin and Applications of Brainwaves: A Review, Our Experience

and Hypothesis Related to Microgravity and the Question on Soul. Zamzuri Idris, Mustapha Muzaimi, Rahman Izaini Ghani, Badrisyah Idris, Regunath Kandasamy, Jafri M Abdullah. J. Biomedical Science and Engineering, 2014, 7, 435-445. Published Online June 2014in SciRes.

7. Intraoperative Fluorescence Angiography for Cerebrovascular Neurosurgery in Universiti Sains Malaysia ; Regunath Kandasamy, Zamzuri Idris, Badrisyah Idris, Tan Yew Chin, Abdul Rahman Izaini Ghani, Jafri Malin Abdullah.. Malays J Med Sci. Jul-Aug 2014; 21(4): 69-70.

8. Searching for the Origin through Central Nervous System: A Review and Thought which Related to

Microgravity, Evolution, Big Bang Theory and Universes, Soul and Brainwaves, Greater Limbic System and Seat of the Soul; Zamzuri Idris.. Malays J Med Sci. Jul-Aug 2014; 21(4): 4-11.

9. Visual and sensorimotor cortices mapping during awake resection of lesion on the right

PENERBITAN

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periatrium:Zamzuri Idris, Ch’ng Chee How and Jafri Malin Abdulah; a case report on brainwaves and their peculiar patterns; Innovative Neurosurgery 2014

10.

Zamzuri Idris, Mohd Sofan Zenian, Mustapha Muzaimi, Wan Zuraida Wan Abdul Hamid; Better Glasgow outcome score, cerebral perfusion pressure and focal brain oxygeneration in severely traumatized rain following direct regional brain hypothermia therapy: A prospective randomized study; Asian Journal of Neurosurgery; Vol.9, Issue 3, July-September 2014

11. Neural oscillation, network, eloquent cortex and epileptogenic zone revealed by

magnetoencephalography and awake craniotomy ; Zamzuri Idris, Regunath Kandasamy, Faruque Reza, Jafri M. Abdullah; Asian Journal of Neurosurgery; Vol.9, Issue 3, July-September 2014

12. Macrodactyly and Poliosis in Tuberous Sclerosis Complex ; Teguh Haryo Sasongko, Nur Farrah Dila Ismail, N.A.M.Nik Mohd Ariff and Z.A.M.H. Zabidi-Hussin; Japanese Journal of Clinical Oncology Advance Access published October 15, 2014

13. Time course of motor and cognitive fuctions after chronic cerebral ischemia in rats; Thenmoly Damodaran, Zurina Hassan, Visweswaran NavaRATNAM, Mustapha Muzaimi, Gandi Ng, Christian P.Muller, Ping Liao, Hans C. Dringenberg Behavioral Brain Research 275(2014)252-258

14. Fast Iterative model for Sequential-Selection-Based Applications; Kh. Amirizadeh and R. Mandava.(2014); International Journal of Computers and Technology, 12(7)

7

BIL TAJUK

1. Canadian Association for Neuroscience Meeting, The development of a rat model of chronic cerebral ischemia:effects on motor and cognitive functions; Zurina Hassan, Thenmoly Damodaran, Visweswaran Navaratnam, Hans C. Dringenberg, Christian P Muller;25-28 May 2014; Montreal,Canada

2. International Conference on Pharmaceutical, Medical & Environment Health Sciences

(IPharME 2014), The Effect of Permanent of Common Carotid Arteries on

Electroencephalogram(EEG) in Rat’s Brain; Nor Fasihah Azam, Zurina Hassan, Hans C.

Dringenberg;17-18 September 2014; PARKROYAL Penang Resort

3. 10th International Sport Science Conference 2014, The Relationship between Mental

Toughness, Anxiety and Action Anticipation; H Analuie, M Faruque, S Saha, M Muzaimi; 25-

27 August 2014; Hotel Perdana, Kota Bharu, Kelantan

4. 19th

National Conference on Medical and Health Science 2014; MicroRNA profiling of the

enhanced differentiation of mesenchymal stem cells into neural-like progenitor cells due to

IGF-1 reveal specific miRNA signature; Tee Jong Huat, Amir Ali Khan, Jafri Malin Abdullah,

Hasnan Jaafar; 7-8 September 2014; School of Dental Sciences, Health Campus, University

Sains Malaysia

5. Internatonal Anatomical Sciences and Cell Biology Conference(IASCBC); CB1 receptor –

dependent Mitragynine addiction and impairment of learning and memory;J Nanthini,

Sharif Mahsufi Mansor, Hasnan Jaafar, M Muzaimi;10-13 December 2014; Tzu Chi

University, Hualien, Taiwan

6. 25th Annual Scientific Meeting of Malaysian Society of Neurosciences; Behavioural effects

and motor coordination in Swiss albino mice eposed to chronic treatment of Morphine and

Mitragynine (Ketum phytochemical); Nanthini Jayabalan, Nurul Iman W.Ismail, Muzaimi

Mustapha; 20-22 June 2014; Berjaya Times Square

7. 25th Annual Scientific Meeting of Malaysian Society of Neurosciences; Exploratory and

sucrose hedonic adaptations of Swi ss albino mice in the IntelliCage system following

repetitive exposure to morphine, mitragynine and THC;Nurul Iman W.Ismail, Nanthini

Jayabalan,Sharif Mahsufi Mansor Muzaimi Mustapha; 20-22 June 2014; Berjaya Times

Square

ABSTRAK

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BIL AKTIVITI

TARIKH TEMPAT

1. Eye-Tracking Workshop -En. -Hazim Omar

22-26 Mac 2014 National University Singapore

2. Latihan praktikal penyelidikan Penyelidikan Blood-Brain Barrier Dr Siti Rafidah Yusof

5-18 Mei 2014 Uppsala University, Sweden

3. Canadian Association for Neuroscience Meeting Dr Zurina Hassan

25-28 Mei 2014 Montreal,Canada

4. Training attachment dalam kaedah Miseq

Amplicon Sequencing -Dr Teguh Haryo Sasongko -Nik Mohd Ariff Nik Abdul Malik -Nur Farrahdila Ismail

8-22 Julai 2014 Universiti Putra Malaysia

5. Third Annual World Course In Advanced Techniques In Neurosurgical Oncology Prof. Madya Dr Zamzuri Idris

10-13 Julai 2014 United Kingdom

6. International Conference on Pharmaceutical, Medical & Environment Health Sciences(IPharME 2014) -Nor Fasihah Azam

17-18 September 2014

PARKROYAL Penang Resortr

7. 5th International Neuroscience Symposium -Nurul Iman Wan Ismail -Nanthini a/p Jayabalan

27 September 2014 Monash University Sunway Campus, Kuala Lunmpur

8. Pembentangan kertas kerja di Persidangan “International Conference on Developing Synergies between Islam and Science & Technology For Mankind’s Benefit -Dr Muzaimi Mustapha

1-2 Oktober 2014

International Institute of

Advanced Islamic Studies (IAIS) Kuala

Lumpur

9. 3rd Anatomical Sciences & Cell Biology Conference 2014 -Nanthini a/p Jayabalan

10-13 Disember 2014

Tzu Chi University, Hualien, Taiwan

10. 10th International Sports Science Conference

-Hossein Analuie Adegani 25-27th Ogos 2014

Hotel Perdana, Kota Bharu,

11. 25th Annual Scientific Meeting of Malaysian Society of Neurosciences -Nanthini a/p Jayabalan -Nurul Iman Wan Ismail

20-22 Jun 2014

Hotel Berjaya Times Square, Kuala Lumpur

KEHADIRAN BENGKEL/SEMINAR/LATIHAN

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BIL NAMA ALAT JUMLAH

1. Diffusion Tensor Imaging Dti Software Accessories RM240,000

2. Acer Aspire AXC605-4440W8 RM2,488

3. Dual Picostat-Electrically Isolated RM29,950

4. HP ML350 G8Server CTO RM13,500

5. HP Z420 Workstation RM6,215

6. ACER Aspire AXC605-4460W RM2,700

7. Irradiance Measurement System RM31,601

8. Stand Magnifier RM3,850

9. Video-Tracking System RM27,500

10. Water Maze System RM44,000

11. Rat 5/9 Holes Chamber RM37,400

12. 2-Channel Microelectrode Ac Amplifier USD2849

13. Rodent Homeothermic Blanket RM9,700

14. Egi Hcgsn 120:128 Channel Adult Sens RM14,800

15. Wireless Headstage USD2847

16. Network Storage Server and Accesories RM8,050

SENARAI ASET

10

BIL NAMA PELAJAR UNIVERSITI TARIKH

MULA

TARIKH

TAMAT

1. Amelia Lloyd University of Keele,UK 6 Jun 2014 4 Sept 014

2. Syazwanie Binti

Seri Buana

New Castle University

Medicine Malaysia

16 Jun 2014 11 Julai 2014

3. Peter Hopcroft University of Queensland 6 Mei 2014 12 Jun 2014

BIL JAWATAN JUMLAH

1. Post-Doc 2

2. Pegawai Penyelidik 3

3. Pembantu Penyelidik 7

PELAJAR ELEKTIF/LATIHAN INDUSTRI

SUMBER MANUSIA(GERAN PENYELIDIKAN)

11

1. Wad 2Delima (ICU Neuro)

Bulan Neurosurgeri Neuromedikal

Januari 46 15

Februari 35 8

Mac 56 11

April 57 15

Mei 53 15

Jun 45 11

Julai 60 15

Ogos 59 17

September 50 16

Oktober 66 10

November 49 8

Disember 53 21

Jumlah 629 162

STATISTIK KEMASUKAN PESAKIT BAHAGIAN OTAK DAN SARAF SEPANJANG

TAHUN 2014

12

2. Wad 3 Utara (Wad Bedah Perempuan)

Bulan Neurosurgeri Neuromedikal

Januari 33 13

Februari 26 16

Mac 28 15

April 28 13

Mei 36 7

Jun 48 1

Julai 35 11

Ogos 46 25

September 24 20

Oktober 28 24

November 36 11

Disember 36 21

Jumlah 404 177

13

3. Wad 2 Intan (Wad Bedah Lelaki)

Bulan Neurosurgeri Neuromedikal

Januari 76 30

Februari 85 26

Mac 103 37

April 103 41

Mei 81 25

Jun 99 17

Julai 87 26

Ogos 96 37

September 98 47

Oktober 93 36

November 78 32

Disember 89 54

Jumlah 1088 408

14

4. Wad 1 Selatan (Wad Rehabilitasi Lelaki)

Bulan Neurosurgeri Neuromedikal

Januari 9 28

Februari 9 14

Mac 17 23

April 16 17

Mei 13 10

Jun 12 27

Julai 0 19

Ogos 0 7

September 0 11

Oktober 1 20

November 16 20

Disember 19 16

Jumlah 112 212

15

5. Wad 2S (Wad Bedah Kanak-kanak)

Bulan Neurosurgeri

Januari 20

Februari 24

Mac 37

April 27

Mei 19

Jun 18

Julai 16

Ogos 28

September 23

Oktober 26

November 20

Disember 23

Jumlah 281

16

6. Wad 6S (Wad perubatan kanak-kanak)

Bulan Neuromedikal

Januari 13

Februari 20

Mac 26

April 24

Mei 14

Jun 26

Julai 11

Ogos 25

September 20

Oktober 24

November 19

Disember 20

Jumlah 242

17

7. Klinik Perubatan

Bulan Neuromedikal

Januari 100

Februari 84

Mac 90

April 102

Mei 94

Jun 90

Julai 83

Ogos 96

September 101

Oktober 89

November 86

Disember 122

Jumlah 1137

18

8. Klinik Bedah

Bulan Neurosurgeri

Januari 159

Februari 164

Mac 139

April 140

Mei 136

Jun 135

Julai 145

Ogos 157

September 166

Oktober 125

November 123

Disember 136

Jumlah 1725

19

LAMPIRAN

Lunch Talk oleh ‘Azali Azlan’

Perjumpaan di antara Pengarah P3Neuro, Timbalan Naib Canselor (Akademik & Antarabangsa) dengan En. Tariq Bukrij (Kedutaan Bosnia Herzegovina)

Mesyuarat bersama syarikat Danmedik Sdn. Bhd bagi projek Green Lane

Perbincangan untuk ‘Long

Terms Research Grants(LRGS)

project bersama UTP,

UIAM,UUM, UITM,UTM,

University Nottingham

Malaysia

20

Lawatan daripada Khazanah Nasional bagi tajaan biasiswa pelajar

Perbincangan bersama Biotropics

Malaysia Berhad untuk

kolaborasi masa hadapan

berkaitan ‘potential of clinical

studies’

Perbincangan Penyelidikan Neuroinformatik bersama UTM