MEDICAL SCIENCE SYLLABUS 2012 - 神戸大学医学研究 · PDF fileGastro-intestinal Surgery 82 Hepato-Biliary-Pancreatic Surgery 83 Cardiovascular Surgery 84 Thoracic Surgery 85

MEDICAL SCIENCE

SYLLABUS 2012

Student Affairs Division

Graduate School of Medicine

Kobe University

－General Subjects－

General Basic Subjects

Core Lecture/Core Practice 1

Trends in Medical Research Lectures　

Trends Series 2

Trends Series（GCOE） 3

Trends Topics 4

Special Lecture

Special English 5

Research Proposal A 6

（Training Course for Raising Research Leaders on Signal TransductionMedicine in the Coming Generation）

Research Proposal B 7

（Training Course for Raising Research Leaders on Signal TransductionMedicine in the Coming Generation）

Writing skills in paper preparation and in grant application 8

Developmental ＆ Regenerative Medicine 9

Innovation and industrial application　 10

Special Course on Bioehics 11

Special Course on Clinician-scientist Special Lecture　 12

Special Course on Global Medical Science 13

Special Series of Medical Oncology 14

Special Series of Radiation Oncology 15

Special Series of Palliative Medicine 16

Special Series of Cancer Chemotherapy 17

Internship 18

CONTENTS

－Major Subjects－

Physiology and Cell Biology

Cell Biology 19

Membrane Dynamics 20

Cell Physiology 21

Cellular and Molecular Medicine 22

Neurophysiology 23

Neuronal Signaling 24

Developmental Neurobiology 25

Molecular Brain Science 26

Vascular Biology 27

Genetics 28

Developmental Biology and Regenerative Medicine 29

Biochemistry and Molecular Biology

Biochemistry 30

Molecular Biology 31

Molecular and Cellular Biology 32

Membrane Biology 33

Molecular and Cellular Signaling 34

Signal Transduction 35

Genomic Physiology 36

Molecular Pharmacology and Pharmacogenomics　 37

Pharmacokinetics 38

Integrated Drug Discovery Sciences 39

Pathology

Pathology 40

Diagnostic Pathology 41

Molecular Medicine & Medical Genetics 42

Microbiology and Infectious Diseases

Microbiology 43

Clinical Virology 44

Vaccinology 45

Zoonotic Infection 46

Infectious Disease Control 47

Infectious Disease Pathology 48

Infectious Diseases Therapeutics 49

Parasitology 50

Social/Community Medicine and Health Science

Family & Community Medicine 51

Medical Statistics 52

Food and Drug Evaluation Science 53

Epidemiology 54

Internal Medicine

General Medicine 55

Cardiovascular Medicine(Arrhythmia) 56

Respiratory Medicine 57

Rheumatology & Clinical Immunology 58

Gastroenterology 59

Advanced Medical Technology for Gastroenterology 60

Diabetes and Endocrinology 61

Nephrology 62

Neurology 63

Medical Oncology/Hematology 64

Hematology 65

Internal Related

Radiology 66

Radiation Oncology 67

Functional and Diagnostic Imaging Research 68

Molecular Imaging 69

Endovascular Therapy 70

Pediatrics 71

Child Health and Development 72

General Pediatrics 73

Dermatology 74

Phychiatry 75

Laboratory Medicine 76

Evidence-based Laboratory Medicine 77

Metabolomics Research 78

Medical Infomatics 79

Pharmaceutics 80

Translational Research for Biologics 81

Surgery

Gastro-intestinal Surgery 82

Hepato-Biliary-Pancreatic Surgery 83

Cardiovascular Surgery 84

Thoracic Surgery 85

Pediatric Surgery 86

Surgery Related

Orthopaedics 87

Rehabilitation Medicine 88

Neurosurgery 89

Ophthalmology 90

Otolaryngology-Head and Neck Surgery 91

Urology 92

Obstetrics and Gynecology 93

Plastic Surgery 94

Anesthesiology and Perioperative Medicine 95

Oral and Maxillofacial Surgery 96

Disaster and Emergency Medicine 97

【2012 Medical Science Syllabus】

Subject Core Lecture/Core Practice Class Style Lecuture and practice

Classroom

Language

English and/or

Japanese Credits 2 credits Semester May - June

Supervisors Takayoshi Kuno Day/

Period To be announced at a later date.

Instructors To be announced at a later date.

Theme and

Objectives

Students learn basic knowledge and techniques required for researchers or professional

workers. They should select one from the following topics, biochemistry and molecular biology,

signal transduction, systems science, oncology, infection and immunity, drug discovery and

development, tissue transplantation and regenerative medicine. Before taking practice course,

students must have attend the corresponding lecture.

Description and

Schedule To be announced at a later date.

E v a l u a t i o n

Grades are based on the following:

Lectures: Attendance and participation (80%)

Practices: Performance (60%)

I n f o rma t i o n

R e g a r d i n g

P r epa ra t i on

This class will start in May, and will be conducted in Janapese and/or English.

M e s s a g e Active weekly participation is required.

Textbook and

Reference

Materials

Instructor will distribute materials when necessary.

K e y w o r d s Core knowledge and technique

Remark

1


Subject Trends Series Class Style Lecture

Classroom

Language English Credits 1 credit Semester September - October

Supervisors Tatsushi Igaki Day/



Theme and

Objectives

Learning cutting-edge researches and English from a series of lectures given by four leading scientists in

the field.

Description and

Schedule

“Understanding human deseases by model organisms”

The titles of the lectures will be announced later.

E v a l u a t i o n Grades are based on the following: Attendance (70%) and short comprehensive tests (30%).

I n f o rma t i o n

R e g a r d i n g

P r epa ra t i on

This class will start in September and will be conducted in English.

M e s s a g e Active discussions with lecturers are encouraged.

Textbook and

Reference

Materials


K e y w o r d s Desease model, Model organisms, Cancer, Infectious desease, Signal transduction

Remark

2


Subject Trends Series (Signal Transduction Medicine GCOE） Class Style Lecture

Classroom

Language Japanese Credits 1 credit Semester September-December

Supervisors Masaru Yoshida Day/


Instructors Teachers at Kobe University Graduate School of Medicine and part-time teachers

Theme and

Objectives

This lecture are designed to understand the leading edge of clinical and basic research to elucidate the

core mechanisms by which cancers, metabolic disorders, infectious diseases, and neurological/muscular

disorders are associated with one another, and to establish novel methods for effective diagnosis,

treatment, and prevention of these diseases.

3


Subject Trends Topics Class Style Lecture

Classroom

Language Japanese or English Credits 1 credit Semester 1st,2nd

Supervisors Faculty Members and

Part-time Lecturers

Day/



Theme and

Objectives To gain a global perspective of clinical and basic medicine.

Description and

Schedule

This lecture series systematically provides students with a wide range of topics from basic to clinical

medicine.

E v a l u a t i o n Evaluation is attendance-based (more than 10 lectures required).

I n f o rma t i o n

R e g a r d i n g

P r epa ra t i on

The schedule and content of lectures will be announced later. Students should be responsible to check

the announcement individually.

M e s s a g e Active participation is required.

Textbook and

Reference

Materials

Instructors will distribute teaching materials when necessary.

K e y w o r d s

Remark

4


Subject Special English Class Style Lecture/Seminaｒ

Classroom

Language English Credits 1 credit Semester October-December

Supervisors Takeshi Azuma

Masaru Yoshida

Day/


Instructors Vijay Kharbas

Theme and

Objectives

To develop skills in oral and visual presentation; to build confidence in public speaking in a second

language; and to improve the ability to use persuasive language.

Description and

Schedule

The class will be held weekly. Classes will consist of: 1)Preparing presentation topics; 2)Learning

presentation skills through lecture and practice exercises; 3) In-class presentation to classmates; and 4)

Feedback for improvement of next presentation. It is expected that there will be time for 4-5

presentations during the course, with each one being improved based on in-class feedback. Much of the

work is to be done as homework, as there is limited class time for creating the presentations during class.

Homework is a requirement of the class, and it will be critical to come to class with a finished

presentation after the 2nd week. No preparation is necessary for the first class.

E v a l u a t i o n Grades are based on the following: Regular attendance and participation (５０%),

Effectiveness of Presentations(５０%).

I n f o rma t i o n

R e g a r d i n g

P r epa ra t i on

This class will start in October,and will be conducted in English.

Students are expected to make several presentations in English, with the help and guidance

of the instructor. No previous presentation skill is necessary.

M e s s a g e Active weekly participation is required in order to benefit from and respond to

intructor's feedback.

Textbook and

Reference

Materials

Materials provided by instructor. You will need access to a PC which can be brought to

class each week.

K e y w o r d s

Remark

5


Subject Research Proposal A Class Style Practice

Classroom

Language English Credits 1 credit Semester First Semester



Instructors

All project members of Global Center of Excellence for Education and Research on Signal Transduction

Medicine in the Coming Generation －Bringing up clinician-scientists in the alliance between basic and

clinical medicine－

Theme and

Objectives

Based on knowledge, a technique, research results of students, we develop the skills necessary to write

the study application by English and to plan a study by themselves.

Description and

Schedule

Based on knowledge, a technique, research results of students, they set the research theme for the

signal transduction medicine. To develop the skills necessary to write the study application by English

and to plan their study, the students prepare and submit the English application with the reasearch plan

for clinical and basic medicine.

E v a l u a t i o n

We perform the document examination of the English research proposal and the presentation in English

with the examination based on questions and answers. From points such as the clarity of the study

purpose, the originality of the study plan, the validity of the study plan, a contribution degree to clinical

and basic medicine, and the English ability, we judge it generally.

I n f o rma t i o n

R e g a r d i n g

P r epa ra t i on

Please obey the instructions of the instructors.

M e s s a g e We expect positive action by students.

Textbook and

Reference

Materials

Instructors will distribute materials when necessary.

K e y w o r d s The signal transduction medicine・the leading edge of clinical and basic research

Remark

6


Subject Research Proposal B Class Style Practice

Classroom

Language English Credits 1 credit Semester First Semester



Instructors

All project members of Global Center of Excellence for Education and Research on Signal Transduction

Medicine in the Coming Generation －Bringing up clinician-scientists in the alliance between basic and

clinical medicine－

Theme and

Objectives

We develop the skills necessary to do the English writing and to plan a study by themselves. We aim to

improve the ability of English research presentation, and the ability of questions and answers by English.

Description and

Schedule

This recture is for the students of “Training Course for Leaders of Clinician-Scientists and Medical

Researchers.” The students make their research presentation at debrief session for research progress,

and receive helpful guidance from project members of Global Center of Excellence for Education and

Research on Signal Transduction Medicine in the Coming Generation. At the end of year, the students

submit the English research report and make their research presentation by English, and then receive

the evaluation.

E v a l u a t i o n

We evaluate the English result report and the English presentation with the examination based on

questions and answers. From the points such as the progress of the study, the scientific and clinical

contribution degree, adequacy of the study plan, logicality of the oral presentation, the accuracy of

questions and answers, and the communicative competence in English, the students are evaluated.

I n f o rma t i o n

R e g a r d i n g

P r epa ra t i on

Please obey the instructions of the instructors and pay attention to the announcement by office.

M e s s a g e We expect positive action by students.

Textbook and

Reference

Materials

Instructors will distribute materials when necessary.


Remark

7


Subject Writing skills in paper preparation and in grant application Class Style Lecture

Classroom

Language Japanese Credits 1 credit Semester September - October




Theme and

Objectives

In this lecture, each teacher teaches how to give presentation about results of research, write articles of

the life science field and produce the applications of research funds, and the lecture is designed to

improve your skills.

8


Subject Developmental & Regenerative Medicine Class Style Lecture（intensive）

Classroom

Language Japanese Credits 1 credit Semester August 30-31

Supervisors RIKEN Kobe Institute Day/



Theme and

Objectives

Students will experience the frontline research on Developmental ＆ Regenerative Medicine,and what

they learn will be greatly helpful in conducting their research activities.

9


Subject Innovation and industrial application Class Style Lecture

Classroom

Language Japanese Credits 1 credit Semester September - October




Theme and

Objectives

In this lecture, the industy and medical leaders of experiencing the life medicine innovation give a lecture

on the present conditions of collaboration between industry and academia, and futhermore the future

prospects. From this lecture, you get the underlying knowledge for creation of life medicine innovation.

10


Subject Special Course on Bioehics Class Style Lecture

Classroom

Language Japanese Credits 1 credit Semester First Semester



Instructors Teachers at Kobe University Graduate School of Medicine and part-time teachers.

Theme and

Objectives

This lecture is designed to understand the translation researches from basic study to clinical study and

the bioethics about them.

11


Subject Special Course on Clinician-scientist Special Lecture Class Style Lecture

Classroom

Language English Credits 1 credit Semester 1st,2nd



Instructors Inviters from foreign countries and others.

Theme and

Objectives

This lecture are designed to understand the leading edge of clinical and basic research to elucidate the

core mechanisms by which cancers, metabolic disorders, infectious diseases, and neurological/muscular

disorders are associated with one another, and to establish novel methods for effective diagnosis,

treatment, and prevention of these diseases.

Description and

Schedule

"The signal transduction medicine" in this education course is the research field for capturing diseases

from information system to maintain homeostasis of the living body and furthermore studying the disease

mechanisms, diagnosis, treatment, and prevention. Our understanding of individual diseases has

developed, but "The signal transduction medicine" highlights the complexity of the disease that we

cannot elucidate via the approaches according to the specialized field focusing on a single disease and

specialty. In this seminar, Clinician-scieitist, the medical researcher who plays an active part in the

overseas front line, lectures the leading edge of clinical and basic research.

E v a l u a t i o n Attendance records to the lecture (It is necessary to attend more than 5 lectures).

I n f o rma t i o n

R e g a r d i n g

P r epa ra t i on

This class will be held in all year. Please pay attention to the announcement by office.

M e s s a g e I expect the active questions and remarks from the students.

Textbook and

Reference

Materials



Remark

12


Subject Special Course on Global Medical Science Class Style Lecture

Classroom

Language English Credits 1 credit Semester June - October

Supervisors Takashi Matozaki Day/



Theme and

Objectives To understand the basic biological phenomena, which are involved in the cause of human diseases.

Description and

Schedule

This series of cross-disciplinary lectures introduces the basic mechanism of diseases and their

pathophysiology.

E v a l u a t i o n Evaluation is attendance-based (more than 8 lectures required).

I n f o rma t i o n

R e g a r d i n g

P r epa ra t i on

The schedule and content of lectures will be announced later. Students should be responsible to check

the announcement individually.

M e s s a g e Active participation is required.

Textbook and

Reference

Materials


K e y w o r d s

Remark

13


Subject Special Series of Medical Oncology Class Style Lecture

Classroom

Language Japanese Credits 1 (8 Lectures) Semester

September-January

(Tentative)

Supervisors Hironobu Minami

Oncology/Hematology

Day/

Period To be determined.

Instructors To be determined.

Theme and

Objectives

Medical Oncology and Hematology

To gain new and systematic insight intocancer chemotherapy including molecularly targeted

drugs.

To systematically understand pathogenesis and therapy for hematological malignancies.

To obtain basic knowledge for the objectives, designs, and statistical considerations of

clinical trials, and to acquire skills for evaluating clinical evidence.

14


Subject Special Series of Radiation Oncology Class Style Lecture

Classroom

Language Japanese Credits １(8Lectures) Semester September-December

Supervisors Ryohei Sasaki

Radiation Oncology

Day/



Theme and

Objectives

To understand the basics and recent developments in multidisciplinary approach to cancer

care including chemotherapy, palliative care and radiation treatment. To understand not

only clinical practice but also basic science of radiation oncology.

15


Subject Special Series of Palliative Medicine Class Style Lecture

Classroom

Language Japanese Credits １(8Lectures) Semester June-December

Supervisors Yoshihiro Nishimura

Respiratory Medicine

Day/



Theme and

Objectives

The objective is to acquire knowledge and ability that improve the QOL of the patients and families

affected by chronic disease to cancer and other life-threatening, practice palliative medicine to clinical

research and education in this field.

16


Subject Special Series of Cancer Chemotherapy Class Style Lecture

Classroom

Language Japanese Credits １(8Lectures) Semester June-December

Supervisors Midori Hirai

Pharmaceutics

Day/



Theme and

Objectives

Pharmaceutical care in cancer chemotherapy.

Lerning about the multidisciprinary cancer treatment and collaboration with community healthcare

professionals.

17


Subject Internship Class Style Practice

Classroom

Language Japanese Credits 4 credits Semester 1st,2nd

Supervisors Azuma Takeshi Day/

Period

More than 3 mouths, less than 4 months (consecutive)

Period is decided by conference with training destination

Instructors Depend on each internship-enforcement-plan.

Theme and

Objectives

The goal of this course is to acquire practical skills which cannot be learned at university throughout

experience in the field.

And to develop human resources who can play an active role as a ready.

18

Division

Field of Study

Instructors

Major Subject

Title Special Lecture Ⅰ ６ credits Semester 1st

Evaluation

Evaluation Criteria

Title Special Lecture Ⅱ ４ credits Semester 2nd

Evaluation

Evaluation Criteria

Title Seminar ３ credits Semester 1st,2nd

Evaluation

Evaluation CriteriaStudents need to acquire the ability to summarize the knowledgein research papers and make plain presentations.

Theme and ObjectivesIn Seminar for Cell Biology, students cultivate their presentation skill. By reading a serious ofpapers in a given theme, students summarize the background, progresses, and current topicsin the field, and finally make a presentation to other laboratory members.

Cell Biology

Theme and Objectives

Students need to obtain and evaluate experimental data in anoriginal research theme in cell biology.

Written Test　　　・　　○　Oral Test　　　・　　　Research Report

Written Test　　　・　　　Oral Test　　　・　　○　Research Report

Students need to acquire basic knowledge in cell biology. Theyalso need to master basic techniques in the research of cellbiology.


Medical Science Syllabus 2012

Mikio Furuse, Yasushi Izumi, Yukako Oda

Theme and ObjectivesIn Special Lecture II for Cell Biology, students learn how to use novel knowledge andexperimental techniques to solve important questions in cell biology. They evaluate thier dataand plan further experiments. Finally students learn how to summarize the experimental datalogically to write research papers.

In Special Lecture I for Cell Biology, students learn basic knowledge in the research field ofmolecular cell biology from textbooks and original research papers. In addition, students learnbasic techniques in morphology, biochemistry, and molecular biology, which are used in theresearch of modern cell biology.


Cell Biology

19

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria

Title Special Lecture Ⅱ ４ credits Semester 1st,2nd

Evaluation

Evaluation Criteria

Title Seminar ３ credits Semester 2nd

Evaluation

Evaluation CriteriaResearch report and attendance

Theme and ObjectivesWe teach reserch paper reading activity and understanding brain function Our currentlectures are as follows:(1) Molecular mechanism of neurite outgrowth(2) Molecular mechanism of synapse formation(3) Molecular mechanism of neurotransmitter release

Membrane Dynamics


Research report and attendance

Written Test　　　・　　　Oral Test　　　・　　　Research Report


Research report and attendance



Toshiaki Sakisaka

Theme and ObjectivesWe teach new knowledge, experimental techniques, and paper writing concerning brainfunctions. Our current lectures are as follows:(1) Molecular mechanism of neurite outgrowth(2) Molecular mechanism of synapse formation(3) Molecular mechanism of neurotransmitter release

We teach fundamental knowledge and experimental techniques concerning membrane trafficand its molecular mechanism. Our current lectures are as follows:(1) Molecular mechanism of vesicle budding(2) Molecular mechanism of vesicle targeting(3) Molecular mechanism of vesicle docking and fusion


Membrane Dynamics

20

Division

Field of Study

Instructors

Major Subject

Title Special Lecture Ⅰ ６ credits Semester 1st, 2nd

Evaluation

Evaluation Criteria

Title Special Lecture Ⅱ ４ credits Semester 1st, 2nd

Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


K. Yamagata, M. Endo, M. Nishita, Y. Minami

Theme and ObjectivesCell polarity signaling plays important roles in regulating cellular differentiation and inmaintaining stemness of tissue stem cells (or cancer stem cells) and/or progenitor cells. Theaim of Special Lecture II is to learn advanced knowledge of molecular and cell biology with aparticular emphasis on the roles of cell polarity signaling in cellular differentiation andmaintenace of stemness, and to acquire advanced technique to perform well-designedexperiments to unveil important and difficult biological questions. Through Special Lecture II, itis of importance to learn how to write a scientific paper.

Cell polarity and migration are regulated elaborately during developmental morphogenesis, andtheir aberrant regulation is associated with cancers and various inflammations. The aim ofSpecial Lecture I is to learn basic knowledge of cell biology, in particular the regulation of cellpolarity and migration under physiological and/or developmental conditions, and to acquireprinciple molecular and cell biological technique to examine cell polarity and migration underphysiological and pathological conditions. We will also present basic knowledge and techniqueto understand and monitor gene regulation under physiological and pathological conditions.


Cell Physiology

The percentage of attendance and the result of oral test.In some cases, research report will be required.

Theme and ObjectivesIn addition to Special Lectures I & II, through Seminar it is of importance to develop one'sscientific ability to present his or her own findings clearly and logically and to discussimportant biological issues with other scientists. One can also learn how to read andunderstand scientific papers reported by others through Seminar and can develop furtherone's ability to write his or her own papers with high quality.

Cell Physiology (regulation of cell polarity and migration)



Written Test　　　・　　Oral Test　　　・　◯　　Research Report

Written Test　　　・　　　◯　Oral Test　　　・　　Research Report


Written Test　　　・　　◯　Oral Test　　　・　　　Research Report

21

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Susumu Seino, Kohtaro Minami, Tadao Shibasaki, Norihide Yokoi

Theme and ObjectivesTheme:Understanding the latest findings of acquirement and failure in exocytotic function inendocrine cells and writing research papers of your own research.Objectives:1) To read and understand the latest papers regarding mechanisms of regulated exocytosis.2) To understand principles of confocal microscpy, TIRF microscopy, and cell sorter to usethese apparatuses.3) To logically interpret and explain data obtained.4) To write research papers.

Theme:Understanding mechanisms of exocytosis in endocrine cells and learning basic techniques forthe study of exocytosis.Objectives:1) To explain intracellular signals involved in regulated exocytosis.2) To explain roles of key molecules participate in exocytosis.3) To understand priciple of ELISA for quantification of hormones.4) To collect blood samples from and adminster drugs to mice and rats.


Cellular and Molecular Medicine

Achievement of the objectives.

Theme and ObjectivesTheme:Reporting and discussing ongoing researches and the latest research papers.Objectives:1) To report research progress in English.2) To make intelligible presentation with intelligible explanatory materials.3) To make appropreate answers to corresponding questions.4) To participate in discussion and express constructive comments.

Cellular and Molecular Medicine







22

Division

Field of Study

Instructors

Major Subject

Title Special Lecture Ⅰ ６ credits Semester 1st,2nd

Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Masahiro Mori

Theme and ObjectivesStudents learn how to perform experiments and make up a scientific paper, understanding up-to-date knowledge and experimental methods in neuroscience. First they learn general rulesfor preparation of a paper and specific aspects of neurophysiology. Then realize how much isclarified and what hypotheses are proposed in regard to the mechanisms of higher brainfunctions (cognition, emotion, learning and memory). They attend some meetings and discusswith other researchers to exchange up-to-date information.

Students learn basic knowledge, theories and experimental methods and practices ofneurophysiology. They learn more about membrane excitability, synaptic transmission,informational processing in neuronal circuits, motor system, sensory system, autonomicsystem, innate behaviors, and higher brain functions. Furthermore they learn about in vitroneuronal preparation such as primary dissociated neuronal culture, brain tissue culture andacute brain slices, and the in vivo preparation together with the theories and practices of theelectrophysiological methods (patch-clamp recording, intracellular recording, extracellularrecording, and electroencephalogram).


Neurophysiology

more than 60 marks

Theme and ObjectivesStudents learn basic manners for presenting scientific data or papers. They learn how to reada paper correctly, how to prepare slide presentation and how to present data in time. Thenthey participate in progress reports and journal clubs, and present their data in our laboratory.They are also encouraged to do these scientific activities in English to be able to discuss withforeign researchers well.

Neurophysiology


more than 60 marks



more than 60 marks


23

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

Title Seminar ３ credits Semester 1st

Evaluation

Evaluation Criteria


Naoaki Saito, Takehiko Ueyama, Hideyuki Mukai, Naoko Adachi

Theme and ObjectivesThis lecture aims to help participants understand the characteristic signaling pathways usinganimal models and study their involvement in neuronal diseases. The participants take specialsubjects to acquire a wide range of systematic and interdisciplinary knowledge andmethodologies in neuronal signaling in addition to those nurturing the ability of English writing.

This lecture aims to help participants understand basic mechanisms of intracellular signalingnetwork and characteristic signaling pathways in neuron. The basic techniques for molecularbiology and cell biology are also lectured.


Neuronal Signaling

Evaluation will be done by attendance and knowledge.

Theme and ObjectivesThe participants read recent papers related to neuronal signaling, report their results of theexperiments, and acquire more knowledge and methodologies in neuronal signaling in additionto those nurturing the ability of English presentation and writing.

Neuronal Signaling






Written Test　　　・　○　Oral Test　　　・　　　Research Report

24

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria

Title Special Lecture Ⅱ ４ credits Semester 1st

Evaluation

Evaluation Criteria


Evaluation

Evaluation CriteriaIndividuals who can read recent research papers and explaincontents through presentation will pass this course.

Theme and ObjectivesThe journal club is designed for the participants to understand the recent progress andtechnical terms in this field. The participants are expected to learn how to read and writeresearch papers in English through the presentation.

Developmental Neurobiology


Individuals displaying sufficient knowledge in essential embryologyand neuroanatomy will pass this course.



Individuals displaying sufficient knowledge in essential embryologyand neuroanatomy will pass this course.



Toshio Terashima, Satoshi Kikkawa

Theme and ObjectivesDuring this course, we teach the participants the theory and practice of (1) methods to labelneural circuit, (2) methods available for birth ate of neurons, (3) methods to identify geneexpression and expression of their transcripts, morphologically. Participants are expected tounderstand functional meanings of genes through the experiments utilizing mutant mice. Wealso teach the methods how to analyze data and to write research papers.

At the end of this course, the participants are expected to understand (1) functions of genesexpressing during the early embryogenesis, (2) development of neural tube and neural crestfrom which CNS and PNS are developed, respectively, (3) differentiation of neural tube intoprimary and secondary brain vesicles and region-specific gene expression, (4) generation ofcerebral cortex from telencephalon and genes related to corticogenesis, and (5) molecularmechanisms underlying formation of neural circuits.


Developmental Neurobiology

25

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria To master how to make presentation

Theme and ObjectivesStudents will be given opportunities to master the skills to understand the contents and thesignificance of cutting-edge papers on medical and life sciences, summarize important pointsof the papers and make presentation of the papers. Students will learn the skills to presenttheir study in Special Lecture II.

Molecular Brain Science


To perform experiments aiming to fulfill research objectives andto present the results of the study

Research Report

Research Report

To master basic research methods

Research Report


Tatsushi Toda, Kazuhiro Kobayashi, Motoi Kanagawa,Wataru Satake

Theme and ObjectivesBy integrating various research methods including genome analysis, proteomics, cell biology,glycobiology, genetic engineering, and others, students will be given opportunities toparticipate actively in researches that aim to elucidate pathogenesis of muscular dystrophyand Parkinson’s disease, to understand the function of related disease causing genes, todevelop novel intervention aiming for personalized medicine, and to identify genetic factorsthat determine memory and intelligence. Through these studies, students will learn the skills toassemble various experimental methods, interpret data, and summarize data for publication.

The advance of genome science has brought a change in experimental methodology to “systematic andcomprehensive”, through which the entire nucleotide sequence of human genome has been recentlydetermined and the genetic code is now being systematically deciphered (functional analysis). Also it isknown that majority of diseases and biological processes we encounter in our daily lives such aslifestyle-related diseases, higher brain function like memory and intelligence, and others, are affectedby genetic factors, highlighting the immeasurable impacts of genome science on medical and lifesciences. The lecture will expose students to current trends, significance, and development in medicalapplication of genome technology, systematic genetic polymorphism analysis, systematic geneexpression analysis, mouse mutation analysis, proteomic analysis, and other genome sciencemethodologies in current brain research field.


Molecular Brain Science

26

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Masanori Hirashima

Theme and ObjectivesThe vascular system is comprised of hierarchical network and plays a crucial role in tissuehomeostasis by circulating the blood throughtout the body. To investigate the development ofendothelial cells and vascular morphogenesis in vertebrates at the molecular and cellularlevels, advanced knowledge and research methods will be instructed through experiments ofendothelial labelling, gene expression analysis, and so on in transgenic mice of vascularmorphogenesis-related genes. Based on up-to-date insights and research methods, how tomake research plan will be instructed. How to write up scientific papers will also be instructed.

The vascular system is comprised of hierarchical network and plays a crucial role in tissuehomeostasis by circulating the blood throughtout the body. Basic knowledge and researchmethods will be instructed about the development of endothelial cells, vascularmorphogenesis, and structure of hieralhycal vascular network in vertebrates.


Vascular Biology

Ability to read and understand papers in vascular biology and tomake appropriate presentations

Theme and ObjectivesThe vascular system is comprised of hierarchical network and plays a crucial role in tissuehomeostasis by circulating the blood throughtout the body. To gain deep knowledge about thedevelopment of endothelial cells and vascular morphogenesis in vertebrates, tips to read andunderstand representative papers in vascular biology will be instructed.

Vascular Biology


Acquisition of advanced knowledge and techniques in vascularbiology, and skills of manuscript preparetion



Acquisition of basic knowledge and techniques in vascular biology


27

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation CriteriaLevel of achievement in the subject described above

Theme and ObjectivesLearning the ability to give a presentation for discussing research papers on genetic analysesof tissue growth regulation. Also, acquiring the ability to give a presentation in English.

Genetics


Level of achievement in the subject described above



Level of achievement in the subject described above



Tatsushi Igaki

Theme and ObjectivesAcquiring the ability to study the molecular basis of cell-cell communication in tissue growthregulation by extending the knowledge and skills learned in "Special Lecture I" as well as bylearning the research skills in biochemistry and molecular biology. Also, learning the ability towrite research papers.

Learning the basic knowledge of tissue growth, homeostasis, and deseases caused byderegulation of tissue growth/homeostasis in multicellular organisms. Understanding thecutting-edge researches in the field of cell-cell interactions and acquiring the genetic skillsfor studying the molecular basis of cell-cell communications.


Genetics

28

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Masaki Okano, Shin-ichi Nishikawa, Hitoshi Niwa

Theme and ObjectivesJournal club will be held with the research papers of preimplantation development, stem cellbiology, genome biology and epigenetics.

A series of lectures will focus on the basic techniques of molecular biology to understandingdevelopmental biology and regenerative medicine, particularly in relation to preimplantationdevelopment, stem cell biology, genome biology and epigenetics.


Developmental Biology and Regenerative Medicine

Degree of understaning found in the research report

Theme and ObjectivesPractical lesson wiill be held in basic molecular biology techniques to understand theirprinciples.

Developmental Biology and Regenerative Medicine







29

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation CriteriaEvaluate collectively by both the attedance and research reports

Theme and ObjectivesSeminar is intended to obtain up-to-date knowledge on signal transduction research throughjournal club routinely held in Biochemistry division. Students are encouraged to make theirprogress reports in English so as to get discussion ability useful in the international scientificmeetings.

Biochemistry


Evaluate collectively by both the attedance and research reports



Evaluate collectively both by attedance and by research reports



Shun-ichi Nakamura

Theme and ObjectivesBased on knowledge and skills acquired in Special Lecture I, this course is programmed tomaster fundamental requirements, i.e., making hypotheses, prove them through experimentalprocesses and study each step necessary for the publication in the international journals.

Human bodies comprise almost 50 trillion cells, which are highly differentiated and formtissues and organ with a fine tune of collaborate networks which enables a variety of eventsincluding motor function, digestion, immunity and memory formation. 　Disruption of suchnetworks, i.e., gain or loss of function of key molecules in the regulation, may cause a varietyof disorders in motor, metabolism, immunological and brain functions. This course is intendedfor students to become familiar with from basic to up-to-date knowledge on signaltransduction and to master fundamental skills necessary for cell signaling researches.


Biochemistry

30

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation CriteriaEvaluation will be done based on the degree of mastery of the ability tounderstand research papers and to make effective presentations.

Theme and ObjectivesThe aim of Seminar is to acquire the ability to understand scientific papers in the molecularbiology field and to nurture communication skills for conveying his/her thought to others.Through lectures, practices, and individual lessons, students will learn practical knowledge andskills for attaining a deep understanding of research papers and for making effectivepresentations.

Molecular Biology


Evaluation will be done based on the degree of mastery of the advancedknowledge and experimental skills in molecular biology as well as of the paper-writing skills.



Evaluation will be done based on the degree of mastery of the basic knowledgeand experimental skills in molecular biology.



Tohru KATAOKA, Fumi SHIMA, and Hironori EDAMATSU

Theme and ObjectivesThe aim of Special Lecture Ⅱ is to acquire the advanced knowledge and techniques inmolecular biology, and the ability to prepare a scientific paper. Through lectures and practices,students will learn the advanced knowledge on intracellular signaling mechanisms controllingcell growth and differentiation and their abnormalities leading to carcinigenesis as well as theadvanced experimental techniques on recombinant DNA technology, protein chemistry, cellculture, etc . In addition, students will get individual lessons for preparation of a scientificpaper.

The aim of Special LectureⅠis to acquire basic the knowledge and techniques in molecularbiology. Through lectures and practices, students will learn the basic knowledge on thestructure and function of the genes, proteins, cells, etc ., and the basic experimentaltechniques on recombinant DNA technology, protein chemistry, cell culture, etc .


Molecular Biology

31

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Yoshimi Takai

Theme and ObjectivesIn this class, students learn methods to analyze and evaluate roles and modes of action of celladhesion molecules in cellular functions, such as cell movement, proliferation, adhesion, andpolarization. For this purpose, students need to learn up-to-date experimental procedures inbiochemistry, molecular biology, and cell biology, by expanding knowledge and researchtechniques mastered in the Special Lecture I. We aim to publish the research results asresearch articles.

The cellular signaling pathways and their crosstalk are associated with cell movement,proliferation, adhesion, and polarization, and strictly regulate normal ontogeny andorganogenesis. Dysregulation of the signaling pathways results in a variety of pathologicalconditions, such as transformation, invasion and metastasis of cancer cells, as well as neuraldisorders, and atherosclerosis. In this class, students learn basic concepts and experimentalmethods to understand the roles of cell adhesion molecules in regulation of cell movement,proliferation, adhesion, and polarization.


Molecular and Cellular Biology

Based on contents and an attitude of the presentation, andaccuracy of their reply to the scientific questions at the lab

Theme and ObjectivesStudents are instructed to read research papers in the field of cell adhesion molecules tolearn reading skills, way to set up proper experimental plans, and methods to evaluateresearch results for deeper understanding of the molecular mechanism by which cell adhesionmolecules regulate cell movement, proliferation, adhesion, and polarization. In addition,students are required to present contents of the research articles on a regular basis at the labmeetings to improve oral presentation skills.

Molecular and Cellular Biology


Based on contents of the research reports.



Based on contents of the research reports.


32

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation CriteriaEvaluations will be made according to the degree ofaccomplishment in the above subjects.

Theme and ObjectivesThe biological membrane is one of the most fundamental cellular constituents involved in variousphysiological events such as intracellular vesicular trafficking, cell division and cell migration. The keyfeature of the membrane is the significant physical flexibility that supports its dynamic morphologicalchanges. Involved in this process is a group of cytosolic proteins that reversibly interact with lipidbilayer, creating unique curvature thus shape of the membrane. Recent research by many laboratorieshas revealed necessary roles of such proteins in endocytosis, thus is gathering increasing attentionsfrom the scientific community. In this course, students will be trained to understand and follow up thescientific topics not only in this particular research field, but also cell biology in general. Through theintensive discussions, it is aimed that the students will become able to find a creative solution againstpossible obstacles in their own research projects.

Membrane Biology


Evaluations will be made according to the degree ofaccomplishment in the above subjects.



Evaluations will be made according to the degree ofaccomplishment in the above subjects.



Toshiki Itoh, Kazuya Tsujita

Theme and ObjectivesThe state-of-art techniques will be introduced for the visualization of morphological changes inbiological membranes in cells; including optical systems for the visualization of intracellular traffickingthat utilize various fluorescent protein tags or fluorescent chemicals. Students will be also trained fortechniques that enable recapitulation of morphological changes in biological membrane in vitro, by usingfluorescent, differential interference and electron microcopies. Further, biochemical methods for thequantification of molecular interactions between proteins and lipids will be introduced. In the course,the students will master the above top notch methodologies of membrane biology, as well as coordinatetheir own research projects in the field; including membrane morphogenesis and intracellular membranetraffic. The projects will be aimed for publications of their own research papers.

To limit free diffusion of molecules is necessary for creation and maintenance of the order ofbiological system. Cells that constitute our body achieve this by separating their inner spacefrom outer environment with plasma membranes. The ingredients of the cell, so calledorganelles, also utilize biological membranes to protect their luminal space, in order tocontribute to cellular homeostasis. Therefore, the regulation of dynamisms in cellularmembranes plays indispensable role for life, providing the basis of intracellular trafficking andmetabolism. In this course, the students will study the basic principles in the field ofmembrane biology, as well as be trained for tissue culture and genetic transformationtechniques.


Membrane Biology

33

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Takashi Matozaki, Yoji Murata

Theme and ObjectivesAims of this training course will further develop the knowledge and experimental techniquesacquired by students in “Special Lecture Ⅰ”, and make students understand fundamentals of,and the latest progress in signaling mechanisms of bioactive substances, such as hormones,growth factors or differentiation factors. Students can learn basic knowledge and the latestprogress of this research area using a progressive research papers as teaching materials.Furthermore, based on the basic knowledge, instructors give students specific guidance onhow to plan an actual experiment, to process or evaluate the experimental data, and to workup the results into a scientific paper.

A variety of bioactive substances acts on cells in vivo to evoke diverse array of intra- andinter-cellular signaling pathways, and thereby regulates various biological responses. In thistraining course, each student carries out research experiments to understand fundamentalsof, and the latest progress in the signaling mechanisms of bioactive substances, such ashormones, growth factors or differentiation factors. Under the guidance of instructors, eachstudent carries out biochemical, molecular biology, or cell biology experiments, which requirespecial techniques and knowledge.

Biochemistory and Molecular Biology

Molecular and Cellular Signaling

Evaluation will be based on presentation with a question andanswer session in this seminer.

Theme and ObjectivesIn this seminar, to understand fundamentals of the signaling mechanisms of bioactivesubstances, such as hormones, growth factors or differentiation factors, students read thelatest scientific papers regarding this research area under the guidance of instructors.Through this process, students specifically learn how to set up a hypothesis, to plan an actualexperiment or to carry out the experiment. Furthermore, based on the basic knowledge,students are trained for a researcher who can make a plan for the actual researchexperiments and report findings of the research in an oral presentation.

Molecular and Cellular Signaling


Evaluation will be based on reports.



Evaluation will be based on reports.


34

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

Title Seminar ３ credits Semester 1st, 2nd

Evaluation

Evaluation Criteria A comprehensive evaluation by oral test.

Theme and ObjectivesAt our division seminars, choose academic papers related to our research field, understandtheir contents, and present them to us. Deepen your understanding of global affairs andunresolved issues of research, and learn how to plan a specific experiment, how to evaluateresearch method, and how to learn a technique to improve their oral presentation skils.

Signal Transduction


A comprehensive evaluation by attitude to research and report.





Yoshiyuki Rikitake

Theme and ObjectivesDeepen the knowledge about abnormal signaling specific to each disease, and perform a studyby incorporating a new approach from a technical standpoint to improve the research level.

Learn about research methods and basic knowledge of signal transduction abnormalitiesobserved in many diseases, including cancer and lifestyle-related diseases. Understand andperfrom experiments to learn the techniques required for analysis of what signalingmechanisms work within the cells that make up our body so that cells normaly function, howand why abnormal signal transduction occurs, and how the abnormal signaling is involved indiseases.


Signal Transduction

A comprehensive evaluation by attitude to research and report.

35

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Kaoru Sugasawa

Theme and ObjectivesIn this subject, advanced researches will be actually carried out concerning damagerecognition factors involved in DNA repair systems, intracellular regulatory mechanisms ofthose factors, as well as their relationship to signal transduction pathways. The studies wouldinclude: 1) determination of post-translational modification sites of the damage recognitionfactors and analysis of affected functions of the corresponding mutant proteins. 2) search fornovel interacting partners and analysis of phenotypes exhibited by their overexpressionand/or impaired expression. 3) analysis of signal transduction pathways concerning DNAdamage response, such as apoptosis induction. The practical ability will be thus acquired notonly for oral presentation of the experimental results, but also for preparation of originalpapers in English.

This subject is aimed to master basic skills concerning biochemistry, molecular biology, cellbiology, molecular genetics and so on, by carrying out various experiments using humancultured cell lines, which are derived from patients with hereditary defects in DNA repairand/or DNA damage responses. Intended experiments will include functional complementationof the cells by introducing the responsible genes, expression and purification of therecombinant proteins, cell-free DNA repair reactions, cell cycle analysis, apoptosis induction,and live cell imaging with GFP-fusion proteins.


Genomic Physiology

Based on presentation of the contents of articles and Q&A

Theme and ObjectivesEspecially focused on the field of genomic DNA damage, repair and cellular responses,students will read intensively the latest original articles in English and present the contents inthe laboratory. Through such experiences and discussions with other lab members, thissubject is aimed to acquire principal ideas of basic researches, including experimental designand evaluation of results, as well as ability to explore solution of problems encountered duringthe researches.

Genomic Physiology


Based on research presentation and Q&A



Based on research report


36

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

1) understand basic knowledges and techniques in pharmacology and related sciences2) explain theoretical background of experimental techniques


Read and understand papers that have been published in the international journals.Furethermore, you need to present the learned contents and experimental data usingpresentation software in the lab or scientific meetings.

1) read and understand scinetific papers2) understand the purpose of your own research3) have a good presentation skill


1) have advanced knowledges in molecular pharmacology and pharmacogenomics2) can perform original and creative research3) write a scientific paper


The aim of this course is to learn advanced knowledges in molecular pharmacology andpharmacogenomics. In addition, you need to learn information technology to study how to getscientific informations, how to perform original researches and how to write scientific papers.Finally,you need to fulfill requirements for PhD thesis.



Takayoshi Kuno, Yan Ma

Drugs are chemical substances used in the treatment, prevention, or diagnosis of a disease.This course is designed to learn about basic knowledges and techniques, such as biochemistry,molecular biology, cell biology, genetics and basic pharmacology for further study and researchin molecular pharmacology and pharmacogenomics.


Molecular Pharmacology and Pharmacogenomics

Molecular Pharmacology and Pharmacogenomics


37

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

E-mail: [email protected]


Midori Hirai, Mitsuhiro Ohta, Hiroshi Kitagawa

Theme and ObjectivesThe current research projects are as follows;(1) Pharmacokinetics and pharmacodynamics of drugs(2) Tailor-made pharmacotherapy based on genotyping(3) Drug metabolizing enzyme and transporter systems in the drug disposition(4) Development of drug delivery systems and optimization of gene therapyCreate a paper based on the research results.

The goal of our research is to elucidate clinical applications for the optimal pharmacotherapy.The aim of this research is to acquire basic knowledge and skills for developing the effectiveand safe pharmacotherapy by means of validating the genotype as well as various medical andmolecular bio informatics available.


Pharmacokinetics

Evaluate the reminor report.

Theme and ObjectivesTo establish the basic knowledge for our research projects, fostering the comprehension ofresearch papers.Attend the seminor or workshop for development of the communication skills with otherhealthcare professionals.

Pharmacokinetics


Make a compreensive assessment through research reports.

Written Test　　　・　○Oral Test　　　・　　　Research Report

Written Test　　　・　　○Oral Test　　　・　　　Research Report

Oral test for asessment of the basic knowledge.

Written Test　　　・　　　Oral Test　　　　○Research Report

38

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation CriteriaAchievement will be evaluated based on both knowledge andtechnical acquirement

Theme and ObjectivesIn this seminar, recent papers and presentations on certain drug discovery project will be pickup for learning about the background and experimental methods used in the studies.Furthermore, many papers and presentations related to the study pick up at first will becarefully followed up to study the changes and improvements in sciences and technologiesutilized in drug discovery research. Additional efforts will be made to translate the knowledgeacquired in the Special Lecture I and II into the practical ability enabling efficient drugdiscovery. Furthermore, case-base teaching will be given to develop comprehensive ability foreffective discussion, report preparation and oral presentation, using student's own researchproject as an actual case.

Advanced Drug Discovery Sciences


Achievement will be evaluated based on both knowledge andtechnical acquirement

Oral Test and Research Report


Achievement will be evaluated based on both knowledge andtechnical acquirement



Yoichi Kurebayashi

Theme and ObjectivesThis course is designed to provide broad knowledge and experimental skills that are necessaryto carry out actual drug discovery research, and understanding of analytical methods tomeasure productivity of pharmaceutical research and development, as well. Focus will be puton advanced, cutting-edge technologies, including pathophysiology-based target validation,high throughput screening, structure-base virtual screening, computer-aided drug design, etc.In addition, lecture will be given to develop ability to analyze and understand the mechanism ofaction and metabolism of drug from a view point of interaction between drug and targetmolecule.

This course is designed to provide basic knowledge about most updated sciences andtechnologies that are utilized in modernized drug discovery research. The major purpose ofthe special lecture I is to develop deep understanding of the process and issues ofpharmaceutical research and development, and cutting-edge science and technology that areenabling state of the art evaluation of drug efficacy, safety, metabolism andpharmacodynamics, and physico-chemical properties.


Integrated Drug Discovery Sciences

39

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

Title Practice ２ credits Semester 1st, 2nd

Evaluation

Evaluation Criteria


Pathology

Pathology

YOKOZAKI, Hiroshi; SEMBA, Shuho

Pathology

Theme and Objectives1) Students will be able to classify and describe the pathologic changes of organs, tissues andcells according to (1) regressive changes, (2) progressive changes, (3) metabolic disturbances,(4) circulatory disturbances, (5) inflammation, (6) neoplasia and (7) malformation and discusstheir etiology and pathogenesis.2) Students will be able to explain the morphologic and functional characteristics of variouspathologic status in each organ.3) Students will be able to analyze the pathobiology of whole organs in diseased individual.


Theme and Objectives1) Students will understand the principles of common procedures of molecular pathology.2) Students will be able to select the appropriate techniques of molecular pathology(immunofluorescence, immunohistochemistry, histochemistry, in situ hybridization, Westernblotting, Northern blotting, Southern blotting, polymerase chain reaction) for the analysis ofspecimens from patients.3) Students will be able to overview the recombinant DNA experiments necessary for themolecular pathological analysis.

Evaluate the levels of achievements of above educational objectivesaccording to the 5-level grading system of Kobe University (S, A, B, Cand F) . Grades S, A, B and C are the passing marks.


Theme and Objectives1) Students will be able to describe the morphological changes of diseased individuals, tissuesand cells with appropriate pathological diagnosis.2) Students will master the conventional histopathological methods.3) Students will master the molecular pathological methods (immunofluorescence,immunohistochemistry, histochemistry, in situ hybridization, Western blotting, Northernblotting, Southern blotting, polymerase chain reaction) for the analysis of diseased specimens.



Evaluate levels of the ability for the diagnosis of surgical, biopsy andautopsy materials

Theme and Objectives1) Students will be able to perform autopsy according to the established method of Rokitanskyor Virchow, then constract proper macroscopic as well as histopathological diagnoses.2) Students will be able to handle surgical and biopsy materials, describe the morphologicalalterations according to the concept of general pathology then place the accuratehistopathological diagnoses.3) By conducting the practices described in 1) and 2), students will be able to reach the levelof pathological diagnosis to pass the board examination by the Japanese Society of Pathology.



40

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

Title Diagnostic Pathology Practice ２ credits Semester 2nd

Evaluation

Evaluation Criteria


Pathology

Diagnostic Pathology

Tomoo Itoh, Chiho Ohbatashi, Shigeo Hara, Yasuhiro Sakai

Diagnostic Pathology, immunohistochemistry

Theme and ObjectivesDiagnostic pathology is one of the most important fields in medicine. To recognize the basic ofthe morphology of the diseases is essential for the various researches. In our department,there is a number of experts of various organs and special diseases. Various studies are ongoing with combination of morphology, immunohistochemsitry, and the other special studies.

　Oral Test　　　

Theme and ObjectivesDiagnostic pathology is one of the most important fields in medicine. To recognize the basic ofthe morphology of the diseases is essential for the various researches. Based on the variousstudies regarding morphology, immunohistochemistry, and the other things, the researchers willdescribe articles on the top-ranking journals.

The results will be graded by the degree of the achievement ofthe preset aims.


Theme and ObjectivesDiagnostic pathology is one of the most important fields in medicine. To recognize the basic ofthe morphology of the diseases is essential for the various researches. In this seminar, welecture about the basics of the pathology, and aim for the improvement of your skills on thereading and recognition of the medical articles and textbook, and the communication.




Theme and ObjectivesDiagnostic pathology is one of the most important fields in medicine. To recognize the basic ofthe morphology of the diseases is essential for the various researches. In this lecture, we willlecture about the grossing practice, diagnostic practice using advanced microscopic system,and the skills about immunohistochemistry.



41

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteriaevaluation of ability to make an experimental design andunderstand and make scientific papers

Theme and ObjectivesIn this class, you can learn how to research work throgh the presentation of your own workand other students' work, and you can understand how to find something important in yourown work throgh discussion with other students and professors. You can learn recentimportant discovery by reading high-profiled scientific journals with the instruction ofprofessors. By this class, you can learn how to present your own work. And you canunderstand Molecular Medicine, Medical Genetics and Pathology by completing your own workas a scientific paper.

Molecular Medicine & Medical Genetics


evaluation of ability to understand of genetical approaches withnormal and pathological tissues



evaluation of ability to understand how to treat with normal andpathological tissues



Professor Yoshitake Hayashi

Theme and ObjectivesDivision of Molecular Medicine & Medical Genetics, Department of Patholog is an emergingdiscipline within pathology, and focuses in the study and diagnosis of disease through theexamination of molecules within organs, tissues or bodily fluids. Our class shares someaspects of practice with both anatomic pathology and clinical pathology, molecular biology,biochemistry, proteomics and genetics, and is sometimes considered a "crossover" discipline.It is multi-disciplinary in nature and focuses mainly on the sub-microscopic aspects of diseaseand unknown illnesses with strange causes. In this class, you can learn how to prepare dataand how to complete your paper with recent important findings.

Pathology is a the most important field that is concerned with the diagnosis of various diseasebased on the gross, microscopic, chemical, immunologic and molecular examination of organs,tissues, and whole bodies. Division of Molecular Medicine & Medical Genetics includes themolecular pathology and diagnostic pathology. The distinction between molecular anddiagnostic pathology is increasingly vague by the introduction of technologies that require newexpertise and the need to provide patients and referring physicians with integrated diagnosticreports. In this class, you can learn what is the pathology and its importance in both practicaland research fields.

Pathology

Molecular Medicine & Medical Genetics

42

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation CriteriaAcquisition status of scientific reading comprehension andpresentation skills

Theme and Objectives　Learning activities include reading papers related to the Special Lecture I and II, andpresentation skill training necessary for scientific research.

Microbiology


Acquisition status of advanced knowledge, advanced experimentalskills, and scientific writing skills



Acquisition status of basic knowledge and basic experimentalskills



Hak Hotta

Theme and Objectives Based upon the basic knowledge and techniques acquired from the Special LectureⅠ,students will systematically learn the microbial pathogenesis and current concepts indiagnostics, therapeutics and prevention. The Special Lecture II will allow students to acquireknowledge and experimental techniques at molecular, cellular and animal levels, which will benecessary for the development of new diagnostic, therapeutic and preventive measures. This course will teach students to make, test, and modify working hypotheses based uponthe experimental data. Students will lean how to write a scientific paper and should be able topublish their own works.

This course is designed for students who want to acquire basic knowledge of microbialgenome structures, gene expression mechanisms, and microbial protein structures andfunctions. Students will learn experimental techniques for analysis of the host-microbeinteractions and the mechanisms of virus proliferation.


Microbiology

43

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Yasuko Mori

Theme and ObjectivesLecture for acquisition of the knowlege and technique of Virology, Cellular biology, Molecularbiology and Immunology Lecture for the way to writing report about Virology, Cellular biology,Molecular biology and Immunology

Lecture for acquisition of the knowlege and technique of Virology, Cellular biology, Molecularbiology and Immunology


Clinical Virology

to acquire how to present the the knowlege and technique

Theme and ObjectivesLecture for acquisition of the knowlege and technique of Virology, Cellular biology, Molecularbiology and Immunology Lecture for the way to presenting the knowlege and technique ofVirology, Cellular biology, Molecular biology and Immunology

Clinical Virology


to acquire how to write the report



to acquire the knowlege and technique of Virology,Cellular biology, Molecular biology and Immunology


44

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Eiji Konishi

Theme and ObjectivesBased on the basic knowledge and technology obtained through "Special Lecture Ⅰ",students will learn (1) further advanced strategies for vaccine construction, (2) methods forevaluating their efficacy and (3) technologies including analytical methods required for theirdevelopment from various aspects. Students will construct a new strategic candidate vaccineand learn the process of vaccine develpment. Further, students will obtain abilities to compiletheir data into papers by their presentation and publishment.

Students will learn (1) medical and social significance of vaccination and (2) methods fordeveloping new strategic vaccines and evaluating their efficacy. Students will (1) constract acandidate vaccine by manipulating genes of pathogens using recombinant technology, (2)analyze expression products by the gene in vitro and (3) learn basic knowledge and technologyfor evaluating vaccine-induced immune responses in experimental animals.


Vaccine Development

Status of the students to obtain abilities to read academic papersand to present these papers

Theme and ObjectivesStudents will obtain abilities to read academic papers relating to "Special Lecture Ⅰ" and"Special Lecture Ⅱ" and to present these papers in a well understandable fashion.

Vaccine Development


Status of the students to learn applied technologies and theability to construct papers

Written Test　　　・　　　Oral Test　　　・　　　○Research Report


Status of the students to learn basic technologies


45

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Kyoko Shinya

Theme and ObjectivesTo understand the emergence mechanisms and pathogenesis of zoonosis in the molecular,cellular and individual levels, Special lecture II includes the experimental trainings for the virushandling and viral genomic sequencing using influenza A viruses. This lecture also includestheoretical planning of experiments and writing of research manuscripts.

Zoonosis are known to become main causes of the recent emerging-reemerging infectiousdiseases. Special Lecture Ⅰ will include learning basic knowledge and research techniques forstudying zoonosis using influenza A viruses.


Zoonotic Infection

Reading comprehension, presentation skill.

Theme and ObjectivesTo further the understanding of emergence and pathogenesis of zoonosis, this seminar willinclude reading of research articles and making the working hypothesis and research plans.

Zoonosis


Acquisition of basic knowledge and technicques for studyingzoonosis



Acquisition of basic knowledge and technicques for studyingzoonosis


46

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation CriteriaStudents are assessed by oral examination and attendancerecord.

Theme and ObjectivesWith the goals of developing and applying tools for controlling/managing infectious diseases,basic techniques in the field are to be mastered in the course.

Infectious Disease Control


Students are assessed by oral examination and attendancerecord.



Students are assessed by oral examination and attendancerecord.



Kawabata Masato, Shirakawa Toshirou

Theme and ObjectivesWith the aim of developing tools for infectious disease management, lectures are delivered onapplications of methods for genetic treatments.

The main objective is to develop and apply tools for infectious disease prevention andmanagement. Since infection diseases have caused an enormous burden of disease,descriptions and explanations are offered on the development as well as applications ofessential tools to control/manage infectious diseases.


Infectious Disease Control

47

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Professor Yoshitake Hayashi

Theme and ObjectivesThe mission of this class on infectious disease pathology is to acquire, advance, anddisseminate knowledge in the fields of infectious diseases that will help identify, control andprevent human and animal disease and/or contribute to public health. You can learn infectiousdiseases through the discussion with other students and professors. In this class, you canlearn how to prepare data and how to complete your paper with recent important findings. Andby this class, you can understand our mission to control the infectious diseases which is atrue threat to our society.

Our research focus is on viral infected hepatitis and hepatology. Main project is to establishthe international network against world-wide spread of emerging and reemerging infectiousdiseases, in systematic and politico-economical as well as Medical and scientic researchaspects. As an education for PhD students, molecular and genetic analysis ofinfectiousdiseases, particularly epidemiologic study and genotype analysis of Hepatitis B virus, HepatitisC virus and Hepatitis E virus (various patient groups in various geographical areas) are beingcarried out. Diagnostic and clinicopathological studies of liver diseases are also beingresearched. In this class you can learn how to research on infectious diseases, particularlyviral hepatitis.


Infectious Disease Pathology

evaluation of ability to make an experimental design andunderstand and make scientific papers

Theme and ObjectivesIn this class, you can learn how to research work of infectious diseases throgh thepresentation of your own work and other students' work, and you can understand how to findsomething important in your own work throgh discussion with other students and professors.You can learn recent important discovery by reading high-profiled scientific journals with theinstruction of professors. By this class, you can learn how to present your own work. And youcan understand overviews of various infectious diseases by completing your own work as ascientific paper.

Infectious Disease Pathology


evaluation of ability to understand of genetical approaches withnormal and pathological tissues



evaluation of ability to understand how to treat with normal andpathological tissues


48

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

Infectious Diseases Therapeutics

Theme and Objectives Studies on diagnostics: epistemology, symptomatology, interpretation of test results,evaluation of safety and cost effectiveness about examinations, Evidence Based Medicine(EBM), production of severity scores and their validation. Also one may participate indevelopment of novel or modified tests such as automated Gram staining machine.



Infectious Diseases Therapeutics

Kentaro Iwata, Goh Ohji

Written Test　　　・　　　Oral Test　　　・　○Research Report


Studies on therapeutics: Antimicrobials, non-antimicrobials, evaluation of therapy outcomes.

We evaluate the quality of studies on diagnostics.

Theme and Objectives Clinical reasoning, patients evaluation, choice of treatment, treatment evaluation.


We evaluate the quality of studies on diagnostics.

Written Test　　　・　　　Oral Test　　　・　　○Research Report

Overall knowledge and understanding on clinical infectiousdiseases.

Theme and ObjectivesLearning how to manage infections and fever of unknown origin.

We evaluate the ability to evaluate patients' condition, reasonabletherapeutic decision making, and understanding of patientevaluation.

○Written Test　　　・　　　Oral Test　　　・　　　Research Report

49

Division

Field of Study

Instructors

Major Subject

Title Special Lecture Ⅰ ６ credits Semester 2nd

Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


UGA Shoji

Theme and ObjectivesWith use of the knowledge studied in the Special Lecture 1, students will use a biologicalapproach to analyze the host-parasite relationship of parasite, Centrocestus armatus. First,students must learn how to set up a hypothesis. Second, devise a method or practical actionto solve this hypothesis. Last, students learn how to analyze data.The goal of this class is to learn the ability to write a scientific paper.

The purpose of this class is to have students generally and systematically understandparasites and/or parasitic diseases. The class will provide background on endemic parasiticdisease explained in terms of hygiene and public health, and an introduction to host-parasiterelationships between man and parasites.In addition, discussion will be held on what kind of contributions individuals can do in the fieldof medicine as someone who studied parasitology.


Parasitology

Based off of in-class presentation

Theme and ObjectivesOn the basis of the knowledge and data learned through Special Lecture 1 and 2, students willprepare a conference/seminar level presentation to be presented in front of the class. Thegoal is to help students learn the skills needed to make accurate and organized presentationsat scientific conferences.

Parasitology


Class attendence is essential

　Research Report

　　　Oral test　　

Class attendence is essential

　　Oral Test　　　

50

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

Title Practice ２ credits Semester 1st,2nd

Evaluation

Evaluation Criteria


There are less medical doctors in rural areas. When patients suffer from uncommon diseases,it is extremely difficult to find appropriate medical doctors and facilities. However, the recentdevelopment of information technology made it possible to support doctors who work sucharea. For example, when the CT scan is done, its images are simultaneously transmitted tothe core hospital where the radiologists can diagnose by seeing them. Our clinical researchdeals with leukemia and its related diseases. We investigate how we can provide medicaltreatment for such patients effectively.

Assessment of the process of research and its outcome totally

Assessment of attitudes toward the on-the-job training and theiroutcome totally

Theme and ObjectivesWe try to find out the health problems in certain community by the fieldwork or by the medicalpractice. Then we investigate how to treat patients effectively under the limited medicalresources. Under the limited human power, we also have to learn how to communicate wellamong the medical coworkers.



Theme and ObjectivesThere are less medical doctors in rural areas. When patients suffer from uncommon diseases,it is extremely difficult to find appropriate medical doctors and facilities. However, the recentdevelopment of information technology made it possible to support doctors who work sucharea. For example, when the CT scan is done, its images are simultaneously transmitted tothe core hospital where the radiologists can diagnose by seeing them. Our clinical researchdeals with leukemia and its related diseases. We investigate how we can provide medicaltreatment for such patients effectively.





Family & Community Medicine

Mitsuhiro Itoh, Masayoshi Hashimoto

Family & Community Medicine

Theme and ObjectivesPeople live long and women deliver less babies. These are current major not only medicalphenomenon but also social problems in Japan. Because of the increase of medical expensesand the limited number of medical doctors, we have strong interest in preventive medicineand/or health science. The preventive medicine will be one of the important medical fields inthe next generation especially in communities where the medical resources are not fullyprovided. These communities will be ideal research fields for the practice of preventivemedicine. Our clinical research deals with the atherosclerosis using the high-resolutionultrasound and pulse-wave velocity. We investigate the association of coronary risk factorsand the development of atherosclerosis. And also we examine the factors which may affectthe development of atherosclerosis epidemiologically in the aspect of family and community.



51

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation CriteriaThe results will be graded by the degree of the achievement.

Theme and ObjectivesTo learn a method for critical appraisal of scientific articles, and through the class discussions,students can develop communication skills to summarize, interpret, and utilize the results inclinical research.

Medical Statistics


The results will be graded by the degree of the achievement.

Written Test　　　・　　　●Oral Test　　　・　　　Research Report

Written Test　　　・　　 ●Oral Test　　　・　　　Research Report

The results will be graded by the degree of the achievement.

Written Test　　　・　　　●Oral Test　　　・　　　Research Report


Isao Kamae

Theme and ObjectivesTo learn advanced knowledge and skills for clinical studies such as EBM, clinical outcomesstudy, and medical technology assessment, and also to write a scientific paper.

To learn basic knowledge and skills of biostatistics to design and interpret clinical studies.


Medical Statistics

52

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation CriteriaAdequate understanding of bibliographic retrieval, data mining,and meta-analysis

Theme and ObjectivesIn this seminar, acquisition of documents regarding effects or side effects of a typicalsupplement or functional food, meta-analysis on them, and construction of scientificevidences are conducted.

Food and Drug Evaluation Science


Adequate understanding of bibliographic retrieval, data mining,and meta-analysis

Research Report

Oral Test

Adequate understanding of effects and side effects of frequentlyused supplements and fuctional foods

Oral Test


Norihiro SAKAMOTO

Theme and ObjectivesAdvanced information analysis techniques are essential for constructing scientific evidencesregarding effects and side effects of supplements and functional foods.The objectives of this lecture are to learn information gathering techniques such asbibliographic retrieval, data mining for analizing large quantities of data, and meta-analysis forbuilding scientice evidences.

Supplements and functional foods are very popular with people becoming health-conscious.However effects and side effects of some of such foods and drugs are not wellanalyzed and known.The objectives of this lecture are to know frequently used supplements and functional foodsand to understand their functional mechanism, effects, and side effects.


Food and Drug Evaluation Science

53

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Hisahide Nishio, MD, PhD, Noriyuki Nishimura, MD, PhD

Theme and ObjectivesTheme: Genetics and oncologyObjectives:(1) To write a short paper on the gene analysis of spinal muscular atrophy. (Nishio)(2) To write a short paper on the analysis of neuroblastoma. (Nishimura)

Theme: Genetics and oncologyObjectives:(1) To understand the advanced research on the genes associated with the development ofspinal muscular atrophy. (Nishio)(2) To understand the outlines of analytical methods of the SMN gene mutations and theireffects. (Nishio)(3) To understand the biological characteristics of neuroblastoma. (Nishimura)(4) To understand the molecular mechanism of neuroblastoma progression. (Nishimura)


Epidemiology

Presentation and participation in the discussion will be figured inthe final grading..

Theme and ObjectivesTheme: Genetics and oncologyObjectives:(1) To present your own ides on how the defective molecular machineries of spinal muscularatrophy lead to the loss of the motor neuron. (Nishio)(2) To present your own ides on how to analyse the molecular mechanism of neuroblastomaprogression. (Nishimura)

Epidemiology, Genetics and Oncology


The research reports (= the papers written in this course) will begraded on the basis of their content, organization, and quality ofwriting.

Written Test　　　・　　　Oral Test　　　・　　〇Research Report


The research reports will be graded on the basis of their content,organization, and quality of writing (or oral presentation).Attendance and class participation will be figured in the finalgrading.


54

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteriaunderstanding of CONSORT statement and interpritation of thevalidity of selected manuscripts

Theme and ObjectivesYou understand the CONSORT statement. You pick up the medical problems of out/inpatients and search the manuscripts related with them. You teach the information about themto medical students and make the students understand the validity and adaptation in clinicalsituation.

evaluation of understanding about clinical validity, medicalmorality and adaptation


Theme and ObjectivesYou search the manuscripts concerned with lifestyle-related illness and vesseral function, andassess the validity and its adaptation. You also present the summary of each manuscripts.

submission of manuscript


Theme and ObjectivesYou will research the interventional trial of lifestyle-realated illness evaluated by above threemethods and establish the manuscript about the relationship of the result and clinicalparameter of lifestyle-related illness.

confirmation of basal technical skill of above three methods


General Medicine

Theme and ObjectivesYou have to understand the cause and clinical significance of large vessel disease andarteriosclerosis in the lifestyle-related illness and learn about the meaning of following method,1) carotid intima-media thickness measured by ultrasonography, 2) endothelial functionmeasured by flow-mediated dilation, 3) degree of arteriosclerosis measured by pulse wavevelocity.



Internal Medicine

General Medicine

Hotsuka Akita

55

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

Title Practice ２ credits Semester 2nd

Evaluation

Evaluation CriteriaOne have to master the basic and clinical skill to examine,diagnose, and treat cardiovascular diseases.

Theme and Objectives Objectives are to take part in the team medical treatment and to master the clinicalknowledge and ability in cardiovascular diseases. Another objectives to develop newdiagnostics and therapies associated with cardiovascular diseases.

One can present one's data and discuss them.




Based on the knowledge of Special Lecture I, the graduate students perform medical researchprojects that are associated with cardiovascular diseases and write scientific papers.

One can write a research paper in English and give scientificconsideration to medical problems.

Theme and ObjectivesTo master the scientific thinking about the pathogenesis of cardiovascular diseases.


One can refer some medical papers and write a research paper inEnglish by oneself.


Cardiovascular Medicine

Theme and ObjectivesTo learn the pathophysiology, diagnosis, and novel therapies of cardiovascular diseases,especially ischemic heart disease, heart failure, and arrythmia. Recent progresses in therapiesof cardiovascular diseases were remarkable and graduate students should catch up with them.Another aim of this program is to acquire the ability to present one's research results, tocomunicate and discuss in English, and to write a research and clinical papers.


Internal Medicine

Cardiovascular Medicine/Arrythmia

Kei-ichi Hirata, Akihiro Yoshida, Tatsuro Ishida, Toshiro Shinke,Tomoya Yamashita, Hidekazu Tanaka, Hiromasa Ohtake, NaotoSasaki

56

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Division of Respiratory Medicine focuses on pathophysiology of respiratory diseases and thedevelopment of new technology: Molecular biology and molecular genetic approaches; Geneticdiagnosis. The students will read a lot of research papers and prepare for writing papers.

Introduction to Paper Writing

Clinical Skill

Theme and ObjectivesFollowings have been extensively carried out in our division:1) Development of new technology and therapy against resoiratory diseases2) Chemo- and/or radiotherapy against thoracic malignancies3) Pariative care in patients with malignant diseases4) Sleep study using polysomonograph in patients with sleep apnea, cardiac diseases, andmetabolic diseases.

Research Presentation


Theme and ObjectivesThe students will present research results in our research meetngs and the both domestic andinternational academic conferences to improve the presentation skills.

Paper Writing



Internal Medicine


Yoshihiro Nishimura, MD, PhD


Theme and ObjectivesDivision of Respiratory Medicine deals with respiratory diseases, including bronchila asthma,COPD, sleep apnea, infectious diseases, cancers and interstitial pneumonia. Main objective inthe graduate course is to study pathophysiology of respiratory disease; Diagnosis andtreatment; New imaging technology; New biochemical assays; and New medication.



57

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

Rheumatology / Clinical Immunology


Internal Medicine

Rheumatology & Clinical Immunology

A. Morinobu, S. Kawano, T. Sugimmoto, Y. Kogata, G. Kageyama

Theme and ObjectivesThe objectives of this course is to learn basic knowledge and techniques in the field ofRheumatology and clinical immunology. The course includes how to read scientific articles,how to design experiments, and how to interpretate the experimental results.


Evaluation Criteria includes the daily activities and an oral test.


Theme and ObjectivesThe objectives of this course is to learn advanced knowledge and techniques in the field ofRHeumatology and clinical immunology. Also how to write a scientfiv paper will be lectured.The goal of the course is to present the data in a scientific meeting and to write an originalpaper.

The objectives of this course is to learn how to present your own data in an oral and posterpresentation. Also how to communicate with other people in a meeting wiil be learned.



Evaluation Criteria includes an original paper and/or oralpresentation at a scientific meeting.


Theme and ObjectivesIn this course, students are expected to learn and participate in the daily practice in the fieldof Rheumatology. Based on the knowledge acquired in the above courses, students areexpected to become highly skilled person in their field.



58

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


The degree of achievement about a report of research



Internal Medicine

Gastroenterology

Takeshi Azuma,Tsuyoshi Fujita,Masaru Yoshida,Yasushi Seo,Yoshihiko Yano

Gastroenterology

Theme and ObjectivesTo understand pathophysiologic mechanisms, diagnosis, and treatments of infectious diseases,inflammatory diseases, and cancers in the field of gastroenterology.



To solve pathophysiologic mechanisms of infectious diseases, inflammatory diseases, andcancers in the field of gastroenterology.To develop advanced medicine in the field of gastroenterology.



Theme and ObjectivesTo obtain medical skills and develop advanced medicine in the field of gastroenterology.



Theme and ObjectivesStudents will introduce scientifically important papers and present their own research results.

59

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation Criteria


Evaluation

Evaluation Criteria


To develop skill for planning the study, analyzing the results, and statistical analysis.To develop innovation by translational researches.



Theme and ObjectivesTo obtain techniques of advanced medicine in the field of gastroenterology.



Theme and ObjectivesTo develop the skill for reading and understanding of the English article about advancedmedicine in the field of gastroenterology.To develop the presentation skill in English.




Internal Medicine

GastroenterologyAdvanced Medical Technology for Gastroenterology

Takeshi Azuma,Takanobu Hayakumo

GastroenterologyAdvanced Medical Technology for Gastroenterology

Theme and ObjectivesTo analyze the pathophysiologic mechanisms of gastrointestinal diseases in order to developthe advanced medicine. We focus on cancers, inflammatory diseases, and infectious diseasesin the field of gastroenterology.



60

Division

Field of Study

Faculty

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation CriteriaList problems based on clinical examination, their assessment,and make clinical plans to solve the problems.

Theme and ObjectivesReceive training to become specialists in diabetes and/or endocrine diseases in clinicalpractice as follows: 1. Learn about various clinical tests to assess pathophysiological states ofdiabetes and endocrine diseases. 2. Perform clinical test on actual cases and assess theresults, and draw the problems. 3. Make clinical plans to solve the problems.

Understanding of papers and presentation


Theme and Objectives1. Read and understand important papers on diabetes and endocrinology, and share thesepapers with the lab members. 2. Develop communication skills through presentation of dataand clinical assessment.

Submission of manuscript in English


Theme and Objectives1. Learn up-dated findings of pathogenesis and pathophysiology clarified by state-of-artmethodology. 2. Learn how to translate basic finding to clinical setting. 3. Perform researchbased on the leading-edge knowledge and technology, analyze the data produced, and write apaper.

Evaluated by the knowledge and skills learned.


Diabetes and Endocrinology

Theme and Objectives1. Gain basic knowledge of the pathogenesis and pathophysiology of diabetes and endocrinediseases. 2. Learn basic methodology necessary for analyses of the pathogenesis andpathophysiology of diabetes and endocrine diseases.



Internal Medicine

Diabetes and Endocrinology

Susumu Seino, Wataru Ogawa, Yoshiaki Kido, Yutaka Takahashi, KazuhikoSakaguchi, Genzo Iguchi, Tetsuya Hosooka, Yushi Hirota, Naoko Hashimoto,Hidenori Fukuoka

61

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation CriteriaAdvances of clinical techniques and knowledge

Theme and ObjectivesWe support to take the qualification of specialist. We teach clinical techniques and knowledgeconcerning nephrolgoy.

Advances of oral presentation




We give necessary lectures to progress the researches.

Research advances

Theme and ObjectivesWe support to learn how to present and describe the research contents. Communication skillsare important in the progress of researches.


Research advances


Nephrology

Theme and ObjectivesFrom the research questions of clinical field, we set up the research aim and strategy. Wesupport the procedures of researches and assist the writing of scientific articles.


Internal Medicine

NephrologyShinichi Nishi, Michio Umezu, Hideki Fujii, Hiraku Kadoguchi, Jun Ito, Akira Fujimori,Shoichi Kin

62

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

Research Report

Research Report

Theme and ObjectivesThe participants will be receiving lectures on neurodegenerative diseases, neuroimmunology,cerebrovascular diseases and other neurological problems by designated guest lecturers andare supposed to understand pathomechanisms of neurological disorders. The participants alsowill be expected to discuss possibilities of disease modifying therapy on these diseases.


Internal Medicine

Neurology

Tatsushi Toda, Fumio Kanda, Hisatomo Kowa, Hirotoshi Hamaguchi, Kenji Sekiguchi,Atsushi Kuga

Neurology

Theme and ObjectivesTo conduct productive and originative studies, there are many processes to be consideredincluding setting a designated goal, information gathering by reported articles, making andcarrying out a definite plan, evaluating your results and writing a report. The participants willbe mastering all these steps and will be supposed to submit at least one original article to amajor journal.

Evaluated by degree of advancement

Research Report

Evaluated by degree of advancement including being board-certificated

Theme and ObjectivesTo study clinical neurology and to improve skills for diagnosis and treatment, the participantswill be expected to take part in seeing patients in neurology ward and outpatient clinics. Theparticipants are supposed to become a board-certificated neurologist.


Research Report

Theme and ObjectivesThe participants will be studying current methods of diagnosis for neurological disorders, suchas neuroimaging and genetic diagnosis, through lectures and reading articles of milestone inneurology. The participants will be also required to improve skills of presentation anddiscussion based on these issues.


63

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Internal Medicine

Medical Oncology/Hematology

Hironobu Minami

Medical Oncology/Hematology

Theme and ObjectivesThe primary goal is to gain insight into the clinical principles and practice of medical oncologyand hematology based on curricula developed by the Japanese Society of Medical Oncologyand the Japanese Society of Hematology. Students should understand the rationale forengaging drug therapy against cancers in multiple organ systems and learn basic oncology,including molecular biology. Students should also obtain basic knowledge and methodology forclinical research and acquire skills of translational research necessary to solve clinicalquestions by basic research.


Theme and ObjectivesObjectives are to learn methods for clinical research in medical oncology and hematologybased on knowledge of clinical pharmacology and advanced anticancer drug therapy, toperform pharmacological research using knowledge of molecular target drugs and theirmechanism of action and resistance, and to obtain the ability to investigate leukemogenesisand new approaches for stem cell transplantation. Final goal is to publish results from thesebasic and clinical research.

Achieve competence level


Theme and ObjectivesGoals are to obtain skills for critical reading of publications, to achieve competency toevaluate the strength of evidence, and to develop skills necessary to incorporate evidence-based medicine into oncology practice. Students should improve their capability for accurateand effective presentation at case conferences and research conferences.




Theme and ObjectivesLearn how to diagnose and treat various cancers in multiple organ sytems includinghematological malignancies. Gain experience with a sufficient number of cases necessary tosuccessfully take certification examinations for medical oncologists and/or hematologistsauthorized by the Japanese Society of Medical Oncology or the Japanese Society ofHematology, respectively. Obtain skills to manage toxicities of stem cell tranplantation. Learnmanagement of oncology patients including supportive therapy, palliative care, andcommunicaton skills to deliver bad news. Students should function as active members of theoncology team and assume a prominent role in the multidisciplinary treatment of cancers.



64

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteriaactive participation in the practice and the outcome

Theme and Objectives1) To obtain the skills to care patients with molecular targeted drugs, chemo/immunotherapy,cell therapy together with supportive cares, which require for approved hematologist.2) To understand how important it is to care patients in an IRB approved clinical study.3) To be clearly aware of ethics/morals because many hematologic diseses are lifethreatening.

active participation in the seminar and the outcome


Theme and ObjectivesTo obtain the skill to deeply understand scientifically important papers. The students willpresent research results in our research meetings and the both domestic and internationalacademic conferences to improve the presentation skills.

active participation in the research and the outcome


Theme and ObjectivesExperimental Medicine: To proceed experiments and learn molecular biology, biochmistry, cellbiology, and genetics. Clinical reserach: To learn how to make a clinical study design whichcan be approved by Internal Review Board (IRB), and proceed through patient care. Bothexperimental and clinical research: To learn data analysis and medical statistics, and writingpapers.

active participation in the research and the outcome


Hematology

Theme and ObjectivesTo acquire basic skills to extract essential questions through the careful observation ofpatients with hematologic diseases. To learn how to appproach those questions clinically andscientifically, including the assessment of published papers, laboratory activity, and patientcare.



Internal Medicine

Hematology

Takeshi Azuma, MD, PhD, Yoshio Katayama, MD, PhD

65

Division

Field of Study

Instructors

Major Subject


2) To learn X-rays dissection and pathologic anatomy for diagnostic imaging

Evaluation

Evaluation Criteria


1) To learn the imaging of various organs and the progress of the imaging in those organs2) To learn the latest finding of the diagnostic imaging in various organs3) To learn the clinical inspection method and clinical application of the utility in the imaging4) Preparation of manuscripts for submission to international and top journals in this field

Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


1) To apply diagnostic imaging techniques in routine clinical practice and clinical study2) To aquire image interpretation skills in clinical practice

Evaluation

Evaluation Criteria



Results of oral test

Level of research report




1) To learn presentation skill for research results at international meeting2) To learn discussion and debate skills for research results presentation at internationalmeeting


Radiology





We conduct the systematic lecture along the following objectives and make use of it in thebedside teaching in the 2nd semester.

3) To learn the representative cases of the imaging in various diseases and build the basics ofclinical studies

1) To learn an imaging device and the imaging principle becoming basic of various imagediagnostics


Internal Related

Radiology

Kazurou Sugimura, Masahiko Fujii, Satoru Takahashi, Junya Konishi, NoriakiSakamoto

66

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation CriteriaEvaluation of research reports.

Theme and ObjectivesPurpose:Understanding the indication of radiation therapy by participating in multidisciplinaryconferences.Outlines:Attend conferences of radiation oncology, head and neck cancers, esophageal cancers andpancreatic cancers. The goal is to present students own opinions about indication,dose/fractionation, irradiation field and dose prescription for individual tumors.

Evaluation of research reports.




Purpose:Understanding radiation therapy for each disease specifically.Outlines:Learn about the indication, dose/fractionation and radiation dose of each disease, such ashead and neck cancers, lung cancers, esophageal cancers and brain tumors.

Evaluation according to students knowledge about basics ofradiation oncology

Theme and ObjectivesPurpose:Understanding the basic methods of radiation treatment plannning.Outlines:Practicing three dimensional treatment planning including image fusion, treatment verificationand dose calculation. The goal is to complete radiation treatment plannings accurately to beapplied in daily clinical practice.


Evaluation according to students knowledge about individualizedtreatment planning.



Radiation Oncology

Ryohei Sasaki, Hideki Nishimura, Kenji Yoshida, Daisuke Miyawaki

Radiation Oncology


Internal Related

Purpose:Understanding the basic theories of radiation oncology.Understanding curative and palliative radiation therapy.Outlines:To understand the basic theories of radiation oncology, radiation biology and radiation physics,and to understand the tolerance dose of organs at risks as well as curative dose of tumorsbased on diagnostic imaging.

67

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Internal Related

Radiology/Functional and Diagnostic Imaging Research

Yoshiharu Ohno, Sumiaki Matsumoto, Takeshi Yoshikawa

Functional and Diagnostic Imaging, Computer-Aided Diagnosis

Theme and Objectives1) To learn foundations of image science for diagnostic imaging2) To learn basic mathematical models for functional and diagnostic imaging research3) To learn anatomy and basics for imaging technique


Theme and Objectives1) To learn basic research methods for functional and diagnostic imaging research2) To learn basic research methods for computer-aided diagnosis research3) To learn state of the art for chest and abdominal diagnostic radiology and functional imaging4) To learn state of the art for computer-aided diagnosis5) Preparation of manuscripts for submission to international and top journals in this field



Theme and Objectives1) To learn presentation skill for research results at international meeting2) To learn discussion and debate skills for research results presentation at internationalmeeting




Theme and Objectives1) To apply functional and diagnostic imaging techniques in routine clinical practice and clinicalstudy2) To apply methodologies of computer-aided diagnosis in clinical study and clinical practice3) To apply chest and abdominal diagnostic and functional imaging analysis for clinical study



68

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Internal Related

Molecular Imaging / Radiology

Michio Senda

Molecular Imaging

Theme and ObjectivesThe students learn the basic principles and techniques for visualizing functions of the brain,tumor, and other organs using PET and other molecular imaging methods.


Theme and ObjectivesThe students learn to design and write a research protocol and participate in the dataacquisition and analysis for molecular imaging research activity to generate a research article.

Report on PET basics


Theme and ObjectivesThe students participate in the internal conferences of the Division of Molecular Imaging,Institute of Biomedical Research and Innovation, and learn to present and discuss researchdata with associates.

Research report, abstract, or full paper.


Clinical skill and team work.

Theme and ObjectivesThe students participate in the clinical research activities regarding molecular imagingperformed in Institute of Biomedical Research and Innovation and practice patient procedure,radionuclide handling, PET scanning and other skills.

Presentation and discussion skill.


69

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Theme:

Evaluation

Evaluation Criteria


Objectives:

Theme:

Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

・To read representative papers on endovascular therapy for various diseases, participate intherapy development and learn research planning

1.To acquire skills for presenting research results and observations in Japanese/English

Theme: ・To hold systematic lectures parallel to the above mentioned and apply this knowledge inclinical practice

Acquiring basic knowledge in endovascular therapy

・To become able to perform endovascular therapy and plan clinical research

Acquiring newest knowledge in endovascular therapy



2. To develop skills for discussing and debating about research results and observations


Objectives:


Internal Related

Endovascular Therapy

Koji Sugimoto, Masato Yamaguchi, Yoshikatsu Nomura

Endovascular Therapy



1.　To learn about newest findings and research methods in endovascular therapy2.　To write papers suitable for publishment in major world medical journals


Objectives:・ To learn about basic treatment methods and diseases・To practice in treatment planning and image diagnosis neccessary for perfoming endovasculartherapy

・ To learn about pre and post procedural management in endovascular therapy

1.To design effective presentations about research achievments and observations inJapanese/English2. To train in holding active debates and discussions based on presentation contents in English

Objectives:

Writting academic papers in English on previously given topics


Holding oral presentations in English at international academicevents about previously given topic in endovascular therapy


Theme:・To analize clinical data while actively participating in clinical practice, and conduct clinical

・To participate in surgical endovascular therapy and development of more effective techniques

70

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Accomplishment of objectives



Internal Related

Pediatrics

Kazumoto Iijima, et al.

Pediatrics

Theme and ObjectivesTo study the diagnosis and treatment on diseases in children



To write papers on diseases in childrenTo study clinical trials in children for the development of new therapies



Theme and ObjectivesTo extract problem lists on diseases in children and resolve the problems



Theme and ObjectivesTo read papers on diseases in childrenTo develop communication skill

71

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation CriteriaAccomplishment of objectives

Theme and ObjectivesTo extract problem lists on development in children and resolve the problems





To study clinical trials in children for the development of new therapies


Theme and ObjectivesTo read papers on child health and developmentTo develop cmmunication skill





Internal Related

Child Health and Development/Pediatrics

Kazumoto Iijima, et al.

Child Health and Development

Theme and ObjectivesTo study the diagnosis and treatment on abnormal development in children

72

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation CriteriaAccomplishment of objectives

Theme and ObjectivesTo extract problem lists on diseases in children and resolve the problems in the clinical fields



Pediatrics

Theme and ObjectivesTo study the diagnosis and treatment on diseases in children



Internal Related

Pediatrics / General Pediatrics

Yasuhiro Takeshima, et al.



Theme and ObjectivesTo write papers on diseases in childrenTo study clinical trials in children for the development of new therapies


Theme and ObjectivesTo read papers on diseases in childrenTo develop communication skill


73

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


absolute assessment



Internal Related

Dermatology

Chikako Nishigori, Masahiro Oka, Hiroshi Nagai, Toshinori Bito, HiroshiNagai, Atsushi Fukunaga

Dermatology

Theme and ObjectivesThe concept and fundamental knowledge of dermatology will be educated. Methods to clarify itsquestions will be instructed.



Methods to propose the hypothesis for clarifying unsolved questions in dermatoses and interpretthe results logically will be educated. In addition, the way to write papers using these results will beinstructed.

absolute assessment

absolute assessment

Theme and ObjectivesA way of thinking for making a diagnosis in dermatology and techniques of clinical tests for thediagnosis will be instructed based on clinical experiences.

absolute assessment


Theme and ObjectivesThrough discussing papers and making presentations of obtained data, an ability of readingcomprehension and a skill of making presentations on the research will be developed.

74

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Achievement of aims

Research Report


Internal Related

Psychiatry

K.Tanaka, T.Kawamata, K.Hashimoto, A.Hishimoto

Psychiatry

Theme and ObjectivesWe aim at mastering that basic clinical and biological skills and knowledges about psychiatricdisorders. It includes clinical examination skills, interview skills, neurological examination skillsand so on.

Research Report

Research Report

We aim at mastering that advanced clinical and biological skills and knowledges aboutpsychiatric disorders. We read journal articles, and learn techniques of paper writing.

Achievement of aims

Achievement of aims

Theme and ObjectivesThe target of this subject is enhancing the capability to clinical examination techniques.Therefore, we can also choose training in professional medical organization.

Achievement of aims

Research Report

Theme and ObjectivesWe aim at mastering that advanced clinical and biological skills and knowledges aboutpsychiatric disorders by reading current journal articles, And practice presentations.

75

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Internal Related

Laboratory Medicine

A. Morinobu, S. Kawano, T. Sugimmoto, Y. Kogata, G. Kageyama

Laboratory Medicine

Theme and ObjectivesThe objectives of this course is to learn basic knowledge and techniques in the field oflaboratory medicine, clinical immunology and blood transfusion. The course includes how toread scientific articles, how to design experiments, and how to interpretate the experimentalresults.


Theme and ObjectivesThe objectives of this course is to learn advanced knowledge and techniques in the field oflaboratory medicine, clinical immunology and blood transfusion. Also how to write a scientfivpaper will be lectured. The goal of the course is to present the data in a scientific meeting andto write an original paper.



Theme and ObjectivesThe objectives of this course is to learn how to present your own data in an oral and posterpresentation. Also how to communicate with other people in a meeting wiil be learned.

Evaluation Criteria includes an original paper and/or oralpresentation at a scientific meeting.



Theme and ObjectivesIn this course, students are expected to learn and participate in the daily practice in the fieldof Rheumatology, blood transfusion and laboratory medicine. Based on the knowledge acquiredin the above courses, students are expected to become highly skilled person in their field.



76

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

Title Practice ２ credits Semester 1st

Evaluation

Evaluation Criteria


Conforence presentation and writing a publishable paper



Internal Related

Evidence-based Laboratory Medicine/Laboratory Medicine

Shunichi Kumagai, Kunihiro Nishimura, Jun Saegusa,Daisuke Sugiyama, Yoshiaki Hagiwara

Evidence-based Laboratory Medicine

Theme and ObjectivesTo acquire basic skills of experimental medicine, including clinical study design, medicalstatistics and clinical immunology, with a goal of establishing Evidence Based Medicine (EBM)in the field of laboratory medicine and developing novel laboratory tests.



To study the Evidence Based Medicine (EBM) and the development research pertaining tonovel diagnostics tests with a view to presenting the results in a conference and submiting apaper to a scientific journal.

Acquisition of basic skills of medical statistics and immunology

Acquisition of clinical skills on clinical laboratory medicine

Theme and ObjectivesTo expand clinical skills through modern clinical and experimental laboratory medicine.

Acquisition of reading comprehension ability and presentationskills


Theme and ObjectivesTo obtain reading comprehension ability and presentation skills through small group discussionand reading the latest articles on laboratory medicine.

77

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


It is evaluated by achivement of research report.



Internal Related

Metabolomics Research

Masaru Yoshida

Metabolomics Research

Theme and ObjectivesIn this lecture, to understand the omics (Metabolomics and Proteomics) for disease diagnosis,you learn the basic knowledge and skill of the analysis technology using mass spectrometer,and then understand the clinical significance.



In this lecture, you analyze various diseases by omics technology (Metabolomics andProteomics), and investigate the target molecules. The goal is to lead research results toelucidation of novel cilinical status and advanced medical technology, and also to prepare yourpaper manuscripts based on the research results.



Theme and ObjectivesIn this lecture, you understand highly advanced medical technology using the metabolomics,and aim at developing new advanced medical care.



Theme and ObjectivesIn this lecture, you understand articles about metabolomics, and evaluate the validity of thearticles and their future adaptation. In addition, you aim at developing a communication skill bythe presentation including own study introduction.

78

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Internal Related

Medical Informatics

Eiichi Maeda, Yutaka Takaoka

Medical Informatics

Theme and ObjectivesApplication of the informatics and information technologies in medical fields.To learn the basis of information technologies, digitization of multimedia information, database,and network systems.


Theme and ObjectivesResearch and development of medical information system, electronic medical recoding system,network communication, and security.

Understandings of the basis of Medical Informatics andInformation Technology


Theme and ObjectivesPaper reading and presentation in medical informatics.

Obtain the reseach outcome in medical informatics.


Can the handling of medical information in clinical practice,medical records management, and protection of personalinformation.

Theme and ObjectivesExcercises in medical information processing in clinical practice, clinical informationmanagement, clinical decision analysis, and hospital information management.

Obtain the abilitiy of paper reading and presentation in medicalinformatics.


79

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

Pharmaceutics

Theme and ObjectivesThe goal of our research is to elucidate clinical applications for the optimal pharmacotherapy.The aim of this research is to acquire basic knowledge and skills for developing the effectiveand safe pharmacotherapy by means of validating the genome as well as various medical andmolecular bio informatics available.


Internal Related

Pharmaceutics

Midori Hirai, Takeshi Hirano, Seigo Iwakawa, Tsutomu Nakamura


Written Test　　　・　　　○Oral Test　　　・　　　Research Report

The current research projects are as follows;(1) Pharmacokinetics and pharmacodynamics of drugs(2) Tailor-made pharmacotherapy based on genotyping(3) Drug metabolizing enzyme and transporter systems in the drug disposition(4) Development of drug delivery systems and optimization of gene therapyCreate a paper based on the research results.

Oral test for asessment of the basic knowledge.

Theme and ObjectivesTo establish the basic knowledge for our research projects, fostering the comprehension ofresearch papers.Attend the seminor or workshop for development of the communication skills with physican,nurse and other healthcare professionals.


Make a compreensive assessment through research reports.


Make a compreensive assessment through basic and clinicalpractice.

Theme and ObjectivesBasic training for the tailor-made pharmacotherapy. According to genotyping, practice anddiscuss about the most relevant pharmacotherapy with other health care professionals.

Evaluate the reminor report.


80

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


To evaluate with the attendance and the research report



Internal Related

Translational Research for Biologics

Toshiro Shirakawa MD, PhD

Translational Research for Biologics

Theme and Objectives It has been a growing need to translate the Biologics from basic research (bench) to clinical(bed). Academia still has been taking a great role in basic research of the field of molecularbiology as a source of biologics. The goal of this special lecture is to understand the overviewof clinical trials ranging from pre-clinical to translational reserach, and to lean the basicknowledge and skills can be applied to their research activities.



To perform the case studies of actual development of biologics, as well as to acquireadvanced knowledge about the biologics.

To evaluate with the attendance and the result of oral test


Theme and ObjectivesTo perform the advanced professional training at the biologics manufacturing facility andclinics. The goal of this practice is to acquire the knowledge and research skills, which arerequired in an exploratory clinical trial of biologics.



Theme and ObjectivesTo perform Journal club and Laboratory meetings and to discuss the latest academic papersrelated to the Biologics. The goal of this seminor is to cultivate the reading comprehension ofthe scientific paper and the ability of scientific communication through the academic societyand laboratory meetings.

81

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Theme and Objectives are to research the solution of pathophysiology or the establishment ofthe novel diagnosis and treatment in the field of gastrointestinal surgery. Concretely, in thesurgical oncology focusing on esophageal cancer, gastric cancer and colorectal cancer or in thesurgical therapeutics for inflammatory bowel disease, the solution of pathophysiology and theprogressive knowlege and the skill about diagnosis and treatment are learned. Furthermore, theresults of the study are presented at the research conference and the dissertations aredelivered.

To master the basic knowlege and the skill about pathophysiology,diagnosis and treatment in the field of gastrointestinal surgery.

To master the essential skill of diagnosis and treatment in thesurgical oncology as an expert of gastroenterological surgery andto understand the meaning of the clinical study.

Theme and ObjectivesThe theme and objectives are to learn the skills and the basic knowledge of surgical treatment.We provide three goals to learn. The first is to practice minimally invasive surgery such aslaparoscopic surgery for esophageal cancer, gastric cancer, and colorectal cancer. The secondis to master the implication of the multidisciplinary therapy with a focus on surgery combinedwith radiation therapy, which includes the ion beam therapy, and chemotherapy by the use ofcytotoxic anticancer and molecular target drugs. The third is to understand clinical trials oftranslational advanced medicine such as immunotherapy and gene therapy.

To master the progressive knowlege and the skill aboutpathophysiology, diagnosis and treatment in the field ofgastrointestinal surgery. To make the dissertations.


Theme and ObjectivesThe first is to extract the problems associated standard diagnostic methods and therapies forthe progress level of digestive malignancy, especially in esophagus, stomach and colon. Thesecond is to acquire the skill of making a presentation at the conference following collectingand analyzing recent findings. The third is to select the surgical management appropriate for aclinical state or staging and design a treatment regimen.

To master the progressive knowlege and the skill aboutpathophysiology, diagnosis and treatment in the field ofgastrointestinal surgery. To make the dissertations.



Surgery

Gastro-intestinal Surgery

Daisuke Kuroda

Gastro-intestinal Surgery

Theme and ObjectivesThe theme and objectives are to study the basic knowlege and the skill about pathophysiologyincluding molecular biology, diagnosis and treatment of the tumor or the inflammation in thefield of gastrointestinal surgery. We encourage the ability to analyze the obtained informationscientifically and to master the basic knowlege and the skill. Furthermore, standard surgicaltreatments of the esophageal cancer, gastric cancer and colorectal cancer are learned.



82

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


This is the lecture about liver transplantation, islet and pancreas transplantation, PIHP andparticle beam radiation therapy.It additionally lectures about the regeneration medicine and gene treatment expected to havethe potential to treat Hepato-Biliary-Pancreatic disease in the future.

Report could be also evaluated.


Theme and ObjectivesThis is the lecture about promotion criation of translational research of advanced medicalcare such as living donor liver transplantation, PIHP and particle beam radiation therapy.



Theme and ObjectivesThis is the lecture about understanding the pathophysiology of Hepato-Biliary-Pancreaticdisease and discuss about new diagnostics and treatments and how to write an article bylearning from this lecture.




Surgery

Hepato-Biliary-Pancreatic Surgery

Yonson Ku

Hepato-Biliary-Pancreatic Surgery

Theme and ObjectivesThis is the lecture about surgical diagnostics and treatments of Hepato-Biliary-Pancreaticdisease.



83

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Surgery

Cardiovascular Surgery

Yutaka Okita

Cardiovascular Surgery

Theme and ObjectivesThe aim of this course is to understand general sugery, especially surgical stress and responseof the body. As for cardiovascular surgery, students must learn about valvular , ischemic heart, aortic and peripheral artery diseases. In addition, students need to comprehend the systemof cardiopulmonary bypass, which maintains the circulation of blood and the oxygen content ofthe body during open heart surgery, and be able to troubleshoot.


Theme and ObjectivesAortic surgery (aortic arch and thoracoabdominal aorta) and endovascular aortic repair mustbe understood and learn the mechanism of spinal cord ischemia. Presentation at researchconference is performed at each semester. Research paper on spinal cord protectoin is mustbe completed at the end of the course

minimum of 50 points


Theme and ObjectivesBasic research on 1 of the following themes is chosen; 1) aortic aneurysm: cerebral ischemiain aortic dissection, spinal cord ischmia in thoracoabdominal surgery, and hemodynamics inaortic root surgery; 2) control release of drugs using hydrogel: strengthen vascular wall andprevent graft degradation; 3) invention of small caliber graft; 4) cardiopulmonary bypass.

present a report at research conference



Theme and ObjectivesBasic surgical skills and perioperative care in open heart surgery must be learned.



84

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation CriteriaThe achievement is judged comprehensively.

Theme and ObjectivesStudents will learn Multidisciplinary treatment ageinst primary lung cancer in Kobe UniversityHospital and Hyogo Cancer Center.

The achievement is judged comprehensively.




Gene mutations and their expression disorder in lung cancer are analysed with surgicalspecimens and the relationship with clinico-pathological findings is evaluated.


Theme and ObjectivesCarrying out the presentation of the newest paper will give you expression, reading, andpersuasive ability.





Surgery

Thoracic Surgery

Masahiro Yoshimura

Thoracic Surgery

Theme and ObjectivesDiagnostic methods and medical treatment for respiratory diseases are lectured．

85

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation CriteriaWe assess the level of achivement comprehensively.

Theme and ObjectivesProgram should be incorporated with: (1) surgical techniques and endoscopic techniques, (2)preoperative and postoperative care.

We assess the level of achivement comprehensively.




Graduate students will research on (1) minimally invasive procedures of thoracic andabdominal surgery, (2) strategy for refractory pediatric disorders (airway disease andoncology), (3) organ transplantation using tissue engineering techniques, (4) development ofartificial internal organ for neonate.


Theme and ObjectivesThere must be regular discussions of problems in clinical investigations or experimentalresearch.





Surgery

Pediatric Surgery

Eiji Nishijima, Chieko Hisamatsu

Pediatric Surgery

Theme and ObjectivesGraduate students are expected to have a knowledge and understanding of: (1) basicsciences including genetics, embryology, anatomy, physiology, biochemistry, pathology, andphamacology, (2) clinical behavior, diagnosis and treatment of diseases in pediatric surgery.

86

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

Title Practice ２ credits Semester 1st

Evaluation

Evaluation Criteria

Evaluation by interview and reports to test the achivement.

The aims of this lecture are (1) to learn the latest knowledge and techniques of imaginganalysis and biomechanics to understand correlations between musculoskeletal disorders andpathological changes, (2) to learn editorial techniques of writing a manuscript for presentationof the results.







Theme and ObjectivesThe aims of this practice are (1) to learn diagnostic methods to evaluate musculoskeletaldisorders and trauma and planning techniques for treatment, (2) to learn indications fororthopaedic surgeries, basic techniques of surgery, post-operative treatment, andrehabilitation.



Theme and ObjectivesThe aim of this seminar is to learn how the information of a living body can be detected tounderstand the situation of the disease and how the information can be interpreted fortreatment. The students also learn the skills for communication by reading published articlesand performing oral presentation.

Theme and ObjectivesEtiology, basic science, and treatment for musculoskeletal disorders will be presented, andcorrelations between these diseases and clinical anatomy, physiology, pathology will be alsolectured. Based on the latest insights in the orthopaedics research, contemporary imaginganalysis and surgical techniques will be introduced, and research techniques will be alsopresented.


Surgery Related

Orthopaedics

Prof. Masahiro Kurosaka

Orthopaedics

87

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria




Theme and ObjectivesThe aim of this seminar is to learn how the information of a living body can be detected tounderstand the situation of the impairment, and how the information can be interpreted fortreatment. The students also learn the skills for communication by reading published articlesand performing oral presentation.


The aims of this lecture are (1) to learn the latest knowledge and techniques of imaginganalysis, electro-physiological examination and biomechanics to understand correlationsbetween impairment and pathological changes, (2) to learn editorial techniques of writing amanuscript for presentation of the results.




Theme and ObjectivesThe aims of this practice are to learn treatment methods to evaluate impairment and toindicate for orthosis, physical, occupational and speech therapy.



Theme and ObjectivesEtiology, basic science, and treatment for rehabilitation medicine will be presented, andcorrelations between these diseases and clinical anatomy, physiology, pathology will be alsolectured. Based on the latest insights in the rehabilitaion research, contemporary imaginganalysis and electro-physiological examination and evaluation technique will be introduced, andresearch techniques will be also presented.


Surgery Related

Rehabilitaion Medicine

Prof. Masahiro Kurosaka

Rehabilitation Medicine

88

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

Written Test　　・　　〇　Oral Test　　　・　　〇　　Research Report

Learn advanced knowledge and skills on pathophysiology, diagnostic methods and treatmentmodalities of various neurosurgical diseases. Basic and clinical research work should beperformed to make scientific papers.

Enough basic knowledge and skills are aquired onpathophysiology, diagnostics and therapies.

Basic knowledge and skills are obtained for neurosurgicaldiagnostics and treatments.

Theme and ObjectivesImprove diagnostic ability through clinical cases in the neurosurgical ward. Aquire basicmicrosurgical technique in the operating theater.

Appropriate presentation can be done in the conference andjournal club.

Written Test　　・　　　〇　Oral Test　　・　　〇　Research Report

Theme and ObjectivesCommunication ability is obtained through clinical conference and journal club.

Enough advanced knowledge and skills are aquired and scientificpapers are completed.

Written Test　　・　　〇　Oral Test　　　・　　〇　Research Report


Surgery Related

Neurosurgery

Kohmura E, Hosoda K, Taniguchi M, Sasayama T

Neurosurgery

Theme and ObjectivesLearn basic knowledge and skills on pathophysiology, diagnostic methods and treatmentmodalities of various neurosurgical diseases. Basic knowledge will be also obtained onmolecular biological or genomic aspects of neurosurgical disorders.

Written Test　　　・　　〇 Oral Test　　　・　　　Research Report


89

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation CriteriaAssessment their clinicall skills and techniques acquired duringthe course

Theme and ObjectivesTo experience and obtain the recent techniques on the diagnosis and the treatment in theoutpatient clinic under the supervison.

The presentation including discussion at the meetings to assessthe level of achievement in the PhD research.

Written Test　　　・　　　○　Oral Test　　　・　　　Research Report

Theme and ObjectivesTo understand the recent progress in the research of ocular diseases and to achieve the skillsfor their effective presentation.

The presentation to assess the level of achievement theirunderstanding and knowledge earned about scientific informationon recent progress in the research of ocular diseases.

Written Test　　　・　　　Oral Test　　　・　　　○　Research Report

Theme and ObjectivesOn the basis of the knowledge obtained in Special Lectue I, the experimental design will beconstructed to develop a novel approach. The experimental results should be reported ininternational scientific journals.

The achievement will be evaluated to assess their understandingand knowledge earned about scientific information on recentprogress in the research of ocular disease.

Written Test　　　・　　　Oral Test　　　・　　　○　Research Report

Ophthalmology

Theme and ObjectivesTo learn the experimental skills to investigate the mechanisms of pathogenesis of oculardiseases and to earn clinical updated knowledge in ophthalmology.



Surgery Related

Ophthalmology

Negi A, Tsukahara Y, Nakamura M, Yamada Y, Kanamori A

90

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation CriteriaThe resident can perform neck dissection, endoscopic nasalsurgery, microlaryngosurgery and mastoidectomy under thementorship of instructors.

Theme and ObjectivesTheme: Surgical Skills in Otolaryngology-Head and Neck Surgery.Objectives: At the end of this unit, the resident can perform the standard surgical techniquesfor general diseases and disorders in Otolarygology-Head and Neck Surgery.

The resident can present case reports at academic meeting.




Theme: Intractable Diseases and Disorders in Otolaryngology-Head and Neck SurgeryObjectives: At the end of this unit, the student can recognize, assess diagnose and managethe intractable diseases and disorders in Otolaryngology-Head and Neck Surgery.

The student can perform a comprehensive history and physicalexamination, order appropriate laboratory and diagnostic testing,develop a differential diagnosis, and arrive at a diagnosis ofdiseases and disorders in General Otolaryngology

Theme and ObjectivesTheme: Communication Skills and Clinical Reseach in Otolaryngology-Head and Neck SurgeryObjective: At the completion of this unit, the resident can discuss the nonsurgical andsurgical management of diseases and disorders in general otolaryngology


The student can perform a comprehensive history and physicalexamination, order appropriate laboratory and diagnostic testing,develop a differential diagnosis, and arrive at a diagnosis ofintractable diseases and disorders in Otolaryngology-Head andNeck Surgery.



Surgery Related

Otolaryngology-Head and Neck Surgery

Ken-ichi Nibu, MD, PhD

Otolaryngology-Head and Neck Surgery

Theme and ObjectivesTheme: General Diseases and Disorders in OtolaryngologyObjectives: At the end of this unit, the student can recognize, assess diagnose and managethe diseases and disorders in General Otolaryngology.

91

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Surgery Related

Urology

Masato Fujisawa

Urology

Theme and Objectives"From bed to bench" and "From bench to bed" are the aim of the research in ourdepartment. You learn Urologic oncology, Urolithiathis, Urinry tract infection, ED, Voidingdysfunction, Pediatric urology, Female urology, renal failure, renal transplantation.


Theme and ObjectivesYou learn advanced medicine in urological field. Topics are "Gene therapy for prostatecancer", Cell to cell interaction in testis", and "Mechanism of antimicrobial resistance inurogenital infection".

60%


Theme and ObjectivesThe purpose of this seminar is to get the presentation skills and paper-writing skills inurological field.

60%


Report

Theme and ObjectivesYou learn diagnosis, treatment and management of urologic diseses. Topics are "Roboticsurgery", "Laparoscopic surgery", "Artificial reproductive therapy", "Molecular targetedtherapy for renal cancer", "Renal transplantation", and "Laser in urologic field".

60%


92

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Judgment of acceptance will be determined by research paperand attitude.



Surgery Related

Obstetrics and Gynecology

Hideto Yamada, Hiroya Matsuo, Mineo Yamasaki, Yasuhiko Ebina,Hiroki Morita

Obstetrics and Gynecology

Theme and ObjectivesTo understand human reproduction and reproductive systems.To learn basic knowledge and skills needed to treat patients in Ob/Gyn field.



Endocrinology: To clarify the association between gonadal function and physiopsychicfunction, analyze the efficacy of hormone replacement therapy. Obstetrics: To create novelstrategy for unexplained recurrent miscarriage. To elucidate pathological condition in prenatalinfection. To establish safe Caesarean section in patients with placenta previa. To researchthe diagnostic method for preeclampsia. Gynecologic oncology: To assess clinicopathologicalfactors in patients with gynecologic malignancies. To develop radical surgery with functionalpreservation.

Judgment of acceptance will be determined by research paperand attitude.

Judgment of acceptance will be determined by oral test andattitude.

Theme and ObjectivesTo perform medical care in Ob/Gyn ward. To instruct medical students or residents.

Judgment of acceptance will be determined by oral test andattitude.


Theme and ObjectivesTo review the topics of research, and report the progress of the research regularly.

93

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


To clarify the mechanism of repair after the microsurgical transfer

acquisition of basic knowledement and skill

acquisition of practical application

Theme and ObjectivesClinical trial of microsurgical method of a nerve transfer between facial and sublingual nerves

acquisition of reading comprehesion and presentation skill


Theme and ObjectivesTo study of histological assessment in nerve regeneration after the microsurgical anastomosis

acquisition of progressive skill and development of paper



Surgery Related

Plastic Surgery

Hiroto Terashi

Plastic Surgery

Theme and ObjectivesTo master the method of microsurgical transfer using wth the neurovascular anastomosis



94

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

Theme and Objectives The program develops the students' ability to evaluate and analyze parameters for biologicalreaction to stress.


Surgery Related

Anesthesiology and Perioperative Medicine

Nobuhiro Maekawa, Kahoru Nishina, Masaaki Ueki, Jun Morishita

Anesthesiology and Perioperative Medicine

Acceptance criteria is: Mastering expert knowledge and skills.


Theme and Objectives The program develops the students' ability to understand and interpret the scientificpapers,and to discuss the problem with other reserchers.






The program develops the students' ability to evaluate and treat the patients withperioperative stress.


Theme and Objectives The program develops the students' knowledge and skills on preparation and accomplishmentof research with ischemic animal model.


95

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

Written Test　　　・　　○　Oral Test　　　・　　○　Research Report

This course provides advanced knowledge and skills in oral and maxillofacial surgery. At thesame time students are required to write scientific paper.

attendance record, test result


Theme and Objectives This course intends to provide operation techniques and skills mainly in major surgery.



Theme and Objectives Students sre required to read important articles and to give their comments on the problems.Through this course communication skills are formed.




Surgery Related

Oral and Maxillofacial Surgery

Komori Takahide, et al.

Oral and Maxillofacial Surgery

Theme and Objectives This course provides basic knowledge and skills in oral and maxillofacial surgery. The lecturesalso concern anomaly, deformity, injury, mucosal disease, inflammation, cyst and tumor of oraland maxillofacial region.



96

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Theme and ObjectivesTo master the knowledge and skills on making up medical articles through searching advancedpublications and medical ariticles.


Theme and ObjectivesTo master the communication skills, read and make presentations both on articles regardingDisaster Medicine and Emergency Medicine.

Skills on making up medical articles


Surgery Related

Disaster and Emergency Medicine

Kawashima T, Nakao H, Okada N, Yoshida T, Okashiro M

Disaster and Emergency Medicine

Theme and ObjectivesTo master the basic knowledge and skills both on Disaster Medicine and Emergency Medicine.On the Disaster Medicine, Framework of Disaster Medicine, Preparedness, Response,International Medical Relief and Risk Management should be mastered. On the EmergencyMedicine, Framework of Emergency Medicine, Emergency Medical System, Primary EmergencyCare and Treatment and Intensive Care and Treatment should be mastered.

Requirement of Basic knowledge and skills


Skills of Primary Care and Treatment, Skill of Redponde toDisaster

Theme and ObjectivesTo foster some advanced professionals both on Disaster medicine and Emergency Medicine,master the skills of Primary Emergency Care and Treatment on the ER, and Intensive Careand Treatment and Response to mass-casualties should be mastered through the real clinicalsites.

Master of Communication Skills


97

Documents

MEDICAL SCIENCE SYLLABUS 2012 - 神戸大学 医学研究 · PDF fileGastro-intestinal Surgery 82 Hepato-Biliary-Pancreatic Surgery 83 Cardiovascular Surgery 84 Thoracic Surgery 85

MEDICAL SCIENCE SYLLABUS 2012 - 神戸大学医学研究 · PDF fileGastro-intestinal Surgery 82 Hepato-Biliary-Pancreatic Surgery 83 Cardiovascular Surgery 84 Thoracic Surgery 85