MWO ( flagella 1

Mesosome

Storage granule5Capsule

Ribosome

6

nuclear material L%l& extrachromosomal gene Vi% plosmid

14

"~Zlb&lLndOWP2 W%l'X1fl71U~U (optical density - OD.) blfJ~i spectrophotometer

1 .

2.

3.

4.I;

1 7

( Tobacco mosaic virus - TMV ) Llll'b6&

1 9

21

2 2

A. ( Nakccf icosahedral) 3. ( Naked helical 1 nwlw

23

LPaaiZlJ91fl e n v e l o p e

24

2s

NucleicAcid

DNA I

-

RNA

CapsidEnvelope

EtherSize (nm) of Virus

Present (4 ) Particle Diameter orVirus

Symmetryor Ahsent( -)

SensitivityDiameter x Length

Group

lcosahedral ( -) Insenitive79-80 AdeoovirusIS-20 Picodnarirusa40-50 Papovavirus

complex

(+)

(+I

Sensitive

Sensitive

150-170

230x300

Herpesvirus

PoxvIrus

lcosahedral (-)

- -

20-30 PicornavirusInsensitive

70-80 Reovirus

Sensitive 40-50 Togavirus

150-300 ParamyxovirusSensitive 70x 175 Rhabdovirus

90-120 Orthomyxovirus

Sensitive Oncornavirus

--

_-

-_

_ .

--

&

Human Diseases Causedby the Group.

Respiratory infectioos

Warrs

Chickenpox (varicella)Shingles (zosler)Coldsores : herpes simplex)

Smallpox (variola major)

Polio, colds, intestinalInfections

Respiratory aod intestinalinfections

Encephalitis, yellow fever,Hemorrhagic fever

Measles, mumpsRabieslnlueoza

Animal tumors

a = also called parvovirus

27

Poxvirus

Herpes,virus

Adenovirus

Papovavirus

Parvovirus

6l7bih4bQ l.a=5”ildzmm.wi~au

Arbovirus

Orthomyxovirus

Paramyxovirus

Rhabdovirus

Oncornavirus

Coronavirus

Arenavirus

Togavirus

Diplornavirus ( rmeovirus )

Picornavirus ( rhinovirus LLBZ enterovirus )

Rotavirus

2 8

29

nucleu5 c ONA)

@ gzj9

31

2. entrusion or budding of membrane OilSb&A arboviruses budding

WI7 membrane L&k%& enveloped virus bbdE11JW'Xl b&A H e r p e s virus il:G

?ll% budding “UOJ cytoplasmic membrane.

bE;d@‘$&~XJ~Wb~M~fl~ LiU Lymphocylic choriomeningitis virus ( LCM)

6. Species specific LLitk virus Ii!UbbEIEl 0on - specific.

Characteristic Antibody Interferon

afNSh%h.JSl~Olfl6%tI (Sterilization )

3 6

3 7

3 8

fll%tl%kl9 ( Sterilization by filtration)

2. L&l~W1JLtiUEl1sRl~ ( gastrointestinal tract 1

3 . ~?l&J ( s k i n )” u ,

4. &qmJaZiuihalae - o7katxwwmwua ( genito - urinary tract)

uon5m~thw.G &I tiayU%~l (conjunctiva 1 bbw.f7;llJn7uvm

41

4 2

2523) 520 - 522

Bailey, William R. and Scott, Elvyn G. Diognosric .\licrobiolog.~. 4th. ed ; Saint

Louis : The C.V. Mosby Company. 1974.

Hoyd, Robert F. and Hoerl, Bryan G. Easic~ Medical Microbiology. Boston : Little,

Brown and Company, 1977.

Davis, Bernard I).. et (11. Microbiology. Harper International Edition; Singapore :

Times Printers Sdn. Bhd., 1973.

Frank, Fenner. The biology of animal viruses. vol. : New york : Academic Press,

1968.

Gruiqkshank, Robert., et. al. Medical Microbiology. 12th. ed, vol. II ; London :

The English Language Book Society and Churchill Livingstone, 1975.

Hawker, Lilian E. and Linton, Alan H. Micro-organisms. Fanction, form and

environment. 2nd ed ; London : Edward Arnold (Publishers) Ltd. 1979.

Jawetz, Ernest , Melnick, Joseph L. and Adelberg, Edward A. Revtew of Medico1Microbiology. 11 th. ed ; California : LANGE Medical Publications. 1974.

Pelezar, Michael J., Jr. and Reid, Roger D. Microbiology New York : McGraw

-Hill Book Company, 1971.

Report of a WHO Scientific Group, “interferon Therapy,” Geneva, March 1-4, 1982.

Yamamoto, Tatsuo. and Yokata, Takeshi. “Plasmids of enterotoxigenic Excherichia

co/i H 10497 : Evidence for two heat-stable cnterotoxin genes and

a conjugal transfer system” J. Baderiol. 153 (March 1983) : \352-

1360.