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Faccae corporerum simagni maximpore, sendem nonsequam etur magnatur. Sed quam archic tem que voluptus nate aliquia erumenis alis dia con non re rest, tem. Eritat ut fugiasp ercit, odi qui niscid quiduci disciundero quas mi, quat atia aut ressit optaturit, nullige ndaepudi omnihil in. Doluptam, consequaest, core volor modi debitis as dolorem asperibust, sitiae nonseribus volore veri od ut autem alique prepers pelicil ipsapiet, ommolore, iusdae sam utendis dolorpor ma nonecea turempelles dolenda corem qui aspelec totae. Evenda inimolu ptatem qui occae consequam et re exerum fugia dolore si consequi sit quas et que sint rem fugitioris cuptae. Itae. Optaepe a si doluptatur sam volupta tecest, offic to oditatiorro ex eum idenest et faciden tissim rest enis aut optatia pos dolo is nima sapictur arumque quisitiae commodi atusdam de quae idiam ressitium explacia imo con platur aut moluptas doloruptibea dolupti ommoditatem a volorec epreper iatiis eosandi gnatecuptae secto consent pliquid elestiae reptatiatur, soloremquide Fugitium in nos et accusdam, si doloriam, nonessi ut assum laceperum sapicimus aut que dolupita dolorit et platur as dolorum hillate mporum dio dis se ommolore volupta tiuntib usandictaquo beatus, tem. Ut volo dus que optae et aut la de dolum ratibus, odis sit aliquam doluten totate parcipsape cus erferes reperis mo vellaut quae. Ur sum doloreratest expedit opta doluptas ipsume cus moluptur minto dolestis dolorepudam, quam, cullupt aquodipsae quiasimillor re ex evelend enderum nonsequ atibus eliqui aut volorum reserum fugia consequi consequas quia nonsequam, vel ipsam conecabo. Ut officitem andes min culparumquis ipsam, quissusae quam ipictur alibust, sit accum conseditae exerum qui unt magniti cus, omnis consequo quo excessi Overview The Lancet Commission on malaria eradication SEPTEMBER 2019 Advocacy and Communications Toolkit The report and all findings of The Lancet Commission on malaria eradication are STRICTLY EMBARGOED until 11.30pm UK time/ 6.30pm New York time on Sunday 8 September 2019

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The Lancet Commission on malaria eradication Advocacy & Communications Toolkit | 1www.malariaeradicationcommission.com

Faccae corporerum simagni maximpore, sendem nonsequam etur magnatur. Sed quam archic tem que voluptus nate aliquia erumenis alis dia con non re rest, tem. Eritat ut fugiasp ercit, odi qui niscid quiduci disciundero quas mi, quat atia aut ressit optaturit, nullige ndaepudi omnihil in.

Doluptam, consequaest, core volor modi debitis as dolorem asperibust, sitiae nonseribus volore veri od ut autem alique prepers pelicil ipsapiet, ommolore, iusdae sam utendis dolorpor ma nonecea turempelles dolenda corem qui aspelec totae. Evenda inimolu ptatem qui occae consequam et re exerum fugia dolore si consequi sit quas et que sint rem fugitioris cuptae. Itae. Optaepe a si doluptatur sam volupta tecest, offic to oditatiorro ex eum idenest et faciden tissim rest enis aut optatia pos dolo is nima sapictur arumque quisitiae commodi atusdam de quae idiam ressitium explacia imo con platur aut moluptas doloruptibea dolupti ommoditatem a volorec epreper iatiis eosandi gnatecuptae secto consent pliquid elestiae reptatiatur, soloremquide natem que et repudi incit modiscias explant accus, unt.

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Overview

The Lancet Commission on malaria eradication

SEPTEMBER 2019

Advocacy and Communications Toolkit

The report and all findings of The Lancet Commission on

malaria eradication are STRICTLY EMBARGOED until 11.30pm UK time/

6.30pm New York time on Sunday 8 September 2019

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The Lancet Commission on malaria eradication Advocacy & Communications Toolkit | 2www.malariaeradicationcommission.com

About the Commission

The Lancet Commission on malaria eradication addresses a bold proposition: malaria, one of the most ancient and deadly diseases of humankind, can and should be eradicated before the middle of the 21st century.

The Lancet Commission on malaria eradication was convened in October 2017 to consider the feasibility, affordability, and merit of malaria eradication, to inform global opinion, and to identify priority actions to achieve eradication. Countries and regions face many pressing health and development challenges, of which malaria is just one. Thus, a 21st century commitment to malaria eradication must be justified based on solid evidence that malaria eradication is achievable within a defined time period; that it is worthwhile in relation to societal benefits and the return on investment; and that the alternative to eradication is untenable.

The Commission’s report, publishing in September 2019, synthesizes existing evidence with new epidemiological and financial analyses to demonstrate that malaria eradication by 2050 is a bold but attainable and necessary goal. In the report—the first academic document of its kind—the Commission examines the major operational, biological, and financial challenges on the path to eradication and identifies key solutions that will enable the global malaria community

to bend the curve and achieve a world free of malaria within a generation. The Commission also emphasizes the substantial social and economic benefits of malaria eradication, together with its mutually reinforcing relationship with universal health coverage and global health security.

The CommissionersThe Lancet Commission on malaria eradication is an international group of 26 leading experts with expertise in geospatial mapping, global health financing, disease eradication, drug development, antimalarial drug resistance management, gene drive, medical entomology, disease ecology, health systems, implementation science, global policy and advocacy, and program management. The Commission is a joint endeavor between The Lancet and the Global Health Group at the University of California San Francisco (UCSF).

The Lancet Commission report on malaria eradication

The full report, “Malaria eradication within a generation: ambitious, achievable, and necessary,” will be published by The Lancet on 8 September 2019 at 11:30pm UK time, and will be available for download at www.thelancet.com/commissions/ malaria-eradication.

Once the embargo is lifted, more information about the Commission and the report will be available at www.malariaeradicationcommission.com.

DOWNLOAD

www.malariaeradicationcommission.com

The report and all findings of The Lancet Commission on malaria eradication are strictly embargoed until 11.30pm UK time/

6.30pm New York time on Sunday 8 September 2019

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The Lancet Commission on malaria eradication Advocacy & Communications Toolkit | 3www.malariaeradicationcommission.com

About the ToolkitThis toolkit includes key messages, resources, and multimedia materials to promote global discussion on malaria eradication, and amplify the findings of The Lancet Commission on malaria eradication in the lead-up to, during, and following the publication and global roll-out of the Commission’s full report.

This toolkit is intended for all members of the global malaria community, including communicators, advocates, researchers, implementers, decision-makers, funders, partners, and anyone affected by the disease.

Social media assets can be downloaded on Dropbox.

ContentsCORE MESSAGE 1: Introducing The Lancet Commission on malaria eradication . . . . . . . . . . . . . . . . . . . . . . 04

CORE MESSAGE 2: Malaria eradication is ambitious . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 05

CORE MESSAGE 3: Malaria eradication is achievable . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 06

CORE MESSAGE 4: Malaria eradication is necessary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 07

EXECUTIVE SUMMARY & TECHNICAL BRIEFS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 08

INFOGRAPHIC & BANNER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 09

VIDEO . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .10

EVENTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11

Toolkit Overview

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The Lancet Commission on malaria eradication Advocacy & Communications Toolkit | 4www.malariaeradicationcommission.com

Core Messages

Supporting visuals

A new report from The Lancet Commission on malaria eradication

“The Lancet Commission makes a bold call for eradicating malaria by 2050. I would be thrilled to see this global scourge eradicated even earlier. But we will not achieve eradication within this time frame with the currently available tools and approaches... The good news is that we, the global malaria community, know what we need to do.”

– Dr. Tedros Adhanom GhebreyesusDirector-General, World Health Organization

malariaeradicationcommission.com

“We must all band together to ensure malaria is eliminated community by community, district by district, country by country, region by region, and continent by continent.”

– His Majesty and Ingwenyama King Mswati III

malariaeradicationcommission.com

The Lancet Podcast Listen to an exclusive interview with

Sir Richard Feachem on the bold new report by The Lancet Commission on malaria eradication

thelancet.com/podcasts/malaria-eradication

malariaeradicationcommission.com

MESSAGE 1

Suggested tweets:The new report by @TheLancet Commission on #malariaeradication addresses a bold proposition: that #malaria can be eradicated within a generation #endmalaria #LancetMalaria @MEIatUCSF https://hubs.ly/H0kyS_n0

.@WHO Director-General @DrTedros discusses the bold challenge of #malariaeradication in his Comment on the new @TheLancet Commission report https://hubs.ly/H0kypzm0 #endmalaria

Eswatini’s King Mswati envisions an Africa free from #malaria in his Comment on the new report by @TheLancet Commission on #malariaeradication https://hubs.ly/H0kytXn0 #endmalaria

#endmalaria#LancetMalaria#malariaeradication

Introducing The Lancet Commission on malaria eradication

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The Lancet Commission on malaria eradication Advocacy & Communications Toolkit | 5www.malariaeradicationcommission.com

Malaria eradication is ambitious

Core Messages

Supporting visualsMESSAGE 2

Suggested tweets:

#Malariaeradication is an ambitious and historic goal, and represents the best of human ingenuity #endmalaria #LancetMalaria @TheLancet @MEIatUCSF https://hubs.ly/H0kyS_n0

Written by 26 of the world’s leading experts, a new report by @TheLancet Commission on #malariaeradication argues that #malaria can – and should – be eradicated by 2050 #endmalaria #LancetMalaria https://hubs.ly/H0kyS_n0

.@TheLancet Commission’s report is the first comprehensive academic document to propose solutions to the major operational, biological, and financial challenges on the path to #malariaeradication https://hubs.ly/H0kyS_n0

#endmalaria#LancetMalaria#malariaeradication

Malaria Eradication Within a Generation: Ambitious, Achievable, and Necessary

#MalariaEradication#EndMalaria #LancetMalaria

“For too long, malaria eradication has been a distant dream, but now we have evidence that malaria can and should be eradicated by 2050. This report shows that eradication is possible within a generation. But to achieve this common vision, we simply cannot continue with a business as usual approach. The world is at a tipping point, and we must instead challenge ourselves with ambitious targets and commit to the bold action needed to meet them.”

– Sir Richard Feachem Director, Global Health Group at the University of California, San Francisco, and Lancet Commission Co-chair

malariaeradicationcommission.com

The Lancet Commission on malaria eradication addresses a bold proposition: malaria, one of the most ancient and deadly diseases of humankind, can and should be eradicated before the middle of the 21st century.

malariaeradicationcommission.com

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www.malariaeradicationcommission.com | 6

Malaria eradication is achievable

Core Messages

Supporting visuals

malariaeradicationcommission.com

Malaria Eradication Within a Generation: Ambitious, Achievable, and Necessary

CASE

S O

F M

ALA

RIA

TODAY 2050

How can we further bend the curve and achieve a world free of malaria by 2050?

Global trends are already helping to reduce malaria.

New models demonstrate the added impact of enhanced access to high quality diagnosis, treatment, and vector control.

malariaeradicationcommission.com

SOFTWARE

Strengthen effective management and implementation of

programs

Increase financing and sharpen investment

strategy

Develop and roll out innovative new

technology

FINANCE

HARDWARE

How can we further bend the curve and achieve a world free of malaria by 2050?

MESSAGE 3

Suggested tweets:.@TheLancet Commission’s report synthesizes existing evidence with new analyses to demonstrate that – with the right tools, strategies, and sufficient funding – #malariaeradication can be achieved within a generation https://hubs.ly/H0kypyS0

A report by @TheLancet Commission on #malariaeradication highlights three ways to further bend the curve to ensure that the world is #malaria-free by 2050 or sooner #endmalaria

#Malaria will not be eradicated under a business as usual scenario. Specific actions are required, and must be reinforced by a global commitment to pursue #malaria eradication as a defined, time-bound goal https://hubs.ly/H0kyS_n0

#endmalaria#LancetMalaria#malariaeradication

CASE

S O

F M

ALA

RIA

TODAY 2050

Malaria Eradication Within a Generation: Ambitious, Achievable, and Necessary

How can we further bend the curve and achieve a world free of malaria by 2050?

Save many lives in perpetuity

Improve the quality of life for millions of people across the globe,

strengthen global health security

Contribute to achieving universal health coverage and thesustainable development goals

Promote equity and reduce poverty

SOFTWARE

Success in these three areas will depend on strong leadership and the establishment of accountability mechanisms.

Strengthen effective management and implementation of

programs

Invest in new tools and techniques for collecting, analyzing, and using

data for decision makingMaintain strong investments in

diagnostics, drugs, and vector controlApply radical new approaches in

science to innovations for malaria eradication

Explore gene drive approaches

Increase financing and sharpen investment

strategy

Develop and roll out innovative new

technology

Increase spending by an additional $2 billion per year

Galvanize new donorsEncourage greater domestic financing

Strengthen management capacity

Implement more nimble, data-driven programs

Encourage active community participation

Leverage the private sector

FINANCE

HARDWARE

Engineering the future

We can be the generation to eradicate malaria once and for all.

We stand at the brink of a historic opportunity. By eradicating malaria, we will:

malariaeradicationcommission.com

Global trends are already helping to reduce malaria.

New models demonstrate the added impact of enhanced access to high quality diagnosis, treatment, and vector control.

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The Lancet Commission on malaria eradication Advocacy & Communications Toolkit | 7www.malariaeradicationcommission.com

Malaria eradication is necessary

Core Messages

MESSAGE 4

Suggested tweets:By eradicating #malaria we will: save many lives, improve quality of life, reduce poverty, and contribute to achieving #UHC and the #SDGs #endmalaria @TheLancet @MEIatUCSF @UHC2030 https://hubs.ly/H0kyS_n0

#Malariaeradication will save many lives in perpetuity; it will promote equity and reduce poverty; it will deliver broad benefits to the human welfare and the economy of countries around the world #endmalaria @TheLancet @MEIatUCSF https://hubs.ly/H0kypyS0

#Malariaeradication is a good investment with large social and economic rewards. @TheLancet Commission on #malaria eradication shows the benefits of eradication will greatly exceed the costs #endmalaria @MEIatUCSF https://hubs.ly/H0kyS_n0

Increasing investments by at least an additional US$2 billion annually will accelerate progress towards #malariaeradication. It is critical to support @GlobalFund replenishment #StepUpTheFight #EndMalaria @TheLancet @theglobalfight

#endmalaria#LancetMalaria#malariaeradication

Supporting visuals

malariaeradicationcommission.com

Save many lives in perpetuity

Improve the quality of life for millions of people across the globe,

strengthen global health security

Contribute to achieving universal health coverage and thesustainable development goals

Promote equity and reduce poverty

By eradicating malaria, we will:

“Despite unprecedented progress, malaria continues to strip communities around the world of promise and economic potential. This is particularly true in Africa, where just five countries account for nearly half of the global burden. Malaria eradication is a public health and equity imperative of our generation.”

– Dr. Winnie Mpanju-Shumbusho Board Member, RBM Partnership to End Malaria, and Lancet Commission Co-chair

malariaeradicationcommission.com

malariaeradicationcommission.com

Malaria Eradication Within a Generation: Ambitious, Achievable, and Necessary

CASE

S O

F M

ALA

RIA

TODAY 2050

How can we further bend the curve and achieve a world free of malaria by 2050?

Global trends are already helping to reduce malaria.

New models demonstrate the added impact of enhanced access to high quality diagnosis, treatment, and vector control.

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The Lancet Commission on malaria eradication Advocacy & Communications Toolkit | 8www.malariaeradicationcommission.com

These materials provide an overview of the full report, including the Commission’s methodology, findings, and core conclusions. The executive summary and the report overview are available in English, Chinese, French, and Spanish.

Executive Summary and Technical Briefs

FRANÇAIS

中文

ENGLISH

ENGLISH

ESPAÑOLA

The Lancet Commission on malaria eradication Report Overview | 1

The Lancet Commission on malaria eradication Fifty years after a noble but flawed attempt to eradicate malaria in the mid-20th century, the global malaria community is once again seriously considering eradication. Momentum toward eradication has been building for decades and more than half of the world’s countries are now malaria-free.

Since 2000, there has been a surge of global progress, facilitated by the rollout of new technologies and the substantial growth in political and financial commitment by countries, regions, and their global partners. Between 2000 and 2017, the rate of malaria cases and deaths worldwide declined by an estimated 36% and 60%, respectively.

The Lancet Commission on malaria eradication was convened in October 2017 to consider the feasibility, affordability, and merit of malaria eradication, to inform global opinion, and to identify priority actions for the achievement of eradication. Countries and regions face many pressing development challenges, of which malaria is just one. Thus, a 21st century commitment to malaria eradication must be justified based on solid evidence that it is achievable within a defined time period; that it is worthwhile, in relation to societal benefits and the return on investment; and that the alternative to eradication is untenable.

The Commission’s report, published in September 2019, synthesizes existing evidence with new epidemiological and financial analyses to demonstrate that malaria eradication by 2050 is a bold but attainable and necessary goal. In the report—the first peer-reviewed academic document of its kind—the Commission examines the major operational, biological, and financial challenges on the path to eradication and identifies solutions that will enable the global malaria community to bend the curve and achieve a world free of malaria within a generation. The Commission also emphasizes the substantial social and economic benefits of malaria eradication, together with its mutually reinforcing relationship with universal health coverage and global health security.

“This report by The Lancet Commission on malaria eradication addresses a bold proposition: malaria, one of the most ancient and deadly diseases of humankind, can and should be eradicated before the middle of the 21st century.”

REPORTOVERVIEW

The Lancet Commission on malaria eradication Technical Brief | 1

TECHNICAL BRIEF

Opportunities and actions for malaria endemic countriesThe Lancet Commission on malaria eradication was convened in October 2017 to consider the feasibility, affordability, and merit of malaria eradication, to inform global opinion, and to identify priority actions for the achievement of eradication. The Commission’s report—the first peer-reviewed academic document of its kind—synthesizes existing evidence with new analyses to demonstrate that malaria eradication can be achieved within a generation.

Bending the curve to create a purposefully-driven, engineered future of a world free of malaria by 2050 will require:

» improving malaria program management and implementation and making better use of existing tools, what we call the software of eradication

» rolling out new tools, or the hardware of eradication

» increasing financial investment in malaria elimination and eradication efforts.

Success in these three areas will depend on strong leadership and the establishment of accountability mechanisms at all levels.

The Lancet Commission’s call to action for malaria endemic countries Improving eradication software » Strengthen management capacity. Improving the management

of malaria programs through training is a high priority. National malaria programs have the opportunity to both offer and require management training, particularly for middle management and team leaders on the front line.

» Implement more nimble, data-driven programs. Malaria eradication requires a management approach that is responsive to local circumstances and constantly adjusting in the light of new evidence and the availability of real-time data. National authorities can implement more nimble malaria programs by allowing greater flexibility in administrative procedures, enhancing managerial autonomy at the level of implementation, and supporting a learning-by-doing approach to find practical solutions to local operational problems.

» Use and share data in a timely manner. The Commission anticipates a revolution in data collection, analysis, and use in the next decade, with profound impact on the effectiveness of program management. Data completeness and quality at the national level is already improving with the rollout of digital platforms and tools. However, data needs to be generated and shared more rapidly to strengthen coordination and collaboration at the regional level and to track global progress.

» Leverage the private sector. The Commission identifies two opportunities for active engagement with the private sector that could improve service delivery and efficiency. The first is re-establishing the private market for long-lasting insecticide-treated nets, with close oversight and adequate public subsidies. The second is outsourcing services such as indoor residual spraying or malaria case management to private non-profit and for-profit organizations. Governments must also ensure correct diagnosis, treatment, and reporting of malaria by all public and private health care providers.

» Carefully manage financial transitions, integration, and decentralization. The restructuring of health system financing, operations, and delivery are complex challenges that put countries at risk of resurgence and the loss of hard-won gains. If structural changes are managed carefully in a realistic implementation timeframe, positive outcomes from a responsive and sustainably-resourced health system may be anticipated.

» Actively align malaria eradication with broader health and development goals. Malaria eradication contributes to the achievement of several of the Sustainable Development Goals – including reaching universal health coverage, promoting equity, and reducing poverty – and strengthens global health security. However, this will not occur passively. Deliberate efforts by national malaria programs are essential to ensure that investments in malaria promote broader health and development goals and vice-versa.

Report overviewExecutive Summary

For malaria endemic countries

ENGLISH

The Lancet Commission on malaria eradication Technical Brief | 1

TECHNICAL BRIEF

Opportunities and actions for the international community The Lancet Commission on malaria eradication was convened in October 2017 to consider the feasibility, affordability, and merit of malaria eradication, to inform global opinion, and to identify priority actions for the achievement of eradication. The Commission’s report—the first peer-reviewed academic document of its kind—synthesizes existing evidence with new analyses to demonstrate that malaria eradication can be achieved within a generation.

Bending the curve to create a purposefully-driven, engineered future of a world free of malaria by 2050 will require:

» improving malaria program management and implementation and making better use of existing tools, what we call the software of eradication

» rolling out new tools, or the hardware of eradication

» increasing financial investment in malaria elimination and eradication efforts.

Success in these three areas will depend on strong leadership and the establishment of accountability mechanisms at all levels.

The Lancet Commission’s call to action for the international community Improving eradication software » Develop more flexible procedures. Eradication requires

more nimble guidance on emerging issues and streamlined regulatory pathways for new commodities and tools. WHO can strengthen its critical role in setting global targets, updating technical strategies, and issuing normative guidance by being flexible and in tune with innovation and ambition coming from endemic countries on the front line.

» Support prevention of re-establishment. Countries must develop effective strategies and financial plans for the prevention of re-establishment before they eliminate, but there is relatively little guidance available. WHO and other technical agencies should be proactive in developing guidelines for the prevention of re-establishment. Major funders should continue to co-finance prevention of re-establishment efforts in vulnerable settings.

» Encourage more frequent reporting and launch a global data hub. Advances in information technology that facilitate faster collection, analysis, and use of data will have a profound impact on program management and effectiveness. Prompt and transparent reporting by countries should be encouraged by the Global Fund and the President’s Malaria Initiative. The establishment of a global malaria data repository will be essential in the final stages of eradication.

Rolling out new eradication hardware » Support research, development, and deployment of new tools.

Innovations and new tools are essential for malaria eradication by 2050. New tools will be especially valuable if they improve surveillance, counter drug and insecticide resistance, have long durations of efficacy, and do not require difficult or protracted compliance by individuals or households. Emphasis should be given to endgame tools that can reduce malaria burden in the highest transmission areas and/or prevent re-establishment where elimination has been achieved. Policy discussions must be initiated early across a broad set of stakeholders to clarify regulatory pathways, use-scenarios, and financing options to shorten the time between product launch and widespread use.

For donors

FRANÇAIS

中文

ENGLISH

ESPAÑOLA

The Lancet Commission on malaria eradicationMalaria eradication within a generation:ambitious, achievable and necessary

50 years after a noble but flawed attempt to eradicate malaria in the mid-20th century, the global malaria community is once again seriously considering eradication. Momentum towards eradication has been building for decades, and more than half of the world’s countries are now malaria free. Since 2000, a surge of global progress has occurred, facilitated by the roll-out of new technologies and the substantial growth in political and financial commitment by countries, regions, and their global partners. Annual domestic and international spending on malaria increased from roughly US$1·5 billion in 2000 to $4·3 billion in 2016. Simultaneously, the number of countries with endemic malaria dropped from 106 to 86, the worldwide annual incidence rate of malaria declined by 36%, and the annual death rate declined by 60%.

Inspired by these outstanding achievements, and troubled by a stagnation in progress that saw 55 countries report an increase in cases between 2015 and 2017, The Lancet Commission on malaria eradication (the Commission) was convened to consider whether malaria eradication is feasible, affordable, and worthwhile. In this report of the Commission, we synthesise existing evidence and new epidemiological and financial analyses to show that malaria eradication by 2050 is a bold but attainable goal, and a necessary one given the never ending struggle against drug and insecticide resistance and the social and economic costs associated with a failure to eradicate.

Global social, economic, and environmental trends are, in most places, reducing malaria. Our models show that these trends alone will lead to greatly reduced but still widespread malaria by 2050. When the effects of enhanced access to high-quality diagnosis, treatment, and vector control are factored in, the 2050 projections show a world largely free of malaria, but with pockets of low-level transmission persisting in a belt across Africa, from Senegal in the northwest to Mozambique in the southeast. In view of these projections, we explore the responses to the operational, biological, and financial challenges that are required to bend the curve (ie, to accelerate the decline in malaria cases and deaths) and achieve elimination everywhere outside of Africa by 2030 and worldwide eradication by 2050.

Operational obstacles limit the success of malaria programmes in many countries, including ineffective management, inadequate use of data to inform strategies, poorly incentivised staff, and disengaged communities. Solutions to most of these challenges are available and inexpensive but require access to management training and tools, which many malaria programmes do not have. Strengthening programme management and improving the availability and use of data for decision making are operational priorities which, if addressed, would enhance programme effectiveness and accelerate the path to malaria eradication. Leveraging the expertise and comparative advantages of the private sector and forming close partnerships with private health-care providers will further strengthen performance.

Multiple challenges arise from the complexity of malaria biology: malaria parasites and their mosquito vectors are constantly evolving resistance to widely used drugs and insecticides, the most common methods of parasite detection are not sensitive enough to identify all infections, simian malaria is now common in humans in parts of southeast Asia, and the effectiveness of standard vector control interventions is low in areas with the highest transmission intensity and where outdoor biting is common. Encouragingly, the research and development pipeline for drugs, insecticides, diagnostics, and vector control tools is robust. Promising new products with strong potential to overcome existing challenges have become available in the past five years or are scheduled to roll out over the next decade. Continued investment in research and development will be essential, with prioritisation of technologies that provide long durations of efficacy, do not require difficult or protracted compliance from individuals and households, and drive down malaria in high transmission or otherwise problematic settings.

The cost of malaria eradication is not known and will be highly dependent on managerial efficiency, the efficacy and cost of new tools, and the degree to which interventions can be targeted. Estimates suggest that annual spending of $6 billion or more is required; current global expenditure is approximately $4·3 billion. The Commission believes that an additional

EXECUTIVE SUMMARY

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Malaria Eradication Within a Generation: Ambitious, Achievable, and Necessary

The Lancet Commission on malaria eradication

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The infographic provides an overview of what is needed to “bend the curve” and achieve a word free of malaria by the year 2050, as well as a summary of the potential impact of eradication.

Infographic

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CASE

S O

F M

ALA

RIA

TODAY 2050

Malaria Eradication Within a Generation: Ambitious, Achievable, and Necessary

How can we further bend the curve and achieve a world free of malaria by 2050?

Save many lives in perpetuity

Improve the quality of life for millions of people across the globe,

strengthen global health security

Contribute to achieving universal health coverage and thesustainable development goals

Promote equity and reduce poverty

SOFTWARE

Success in these three areas will depend on strong leadership and the establishment of accountability mechanisms.

Strengthen effective management and implementation of

programs

Invest in new tools and techniques for collecting, analyzing, and using

data for decision makingMaintain strong investments in

diagnostics, drugs, and vector controlApply radical new approaches in

science to innovations for malaria eradication

Explore gene drive approaches

Increase financing and sharpen investment

strategy

Develop and roll out innovative new

technology

Increase spending by an additional $2 billion per year

Galvanize new donorsEncourage greater domestic financing

Strengthen management capacity

Implement more nimble, data-driven programs

Encourage active community participation

Leverage the private sector

FINANCE

HARDWARE

Engineering the future

We can be the generation to eradicate malaria once and for all.

We stand at the brink of a historic opportunity. By eradicating malaria, we will:

malariaeradicationcommission.com

Global trends are already helping to reduce malaria.

New models demonstrate the added impact of enhanced access to high quality diagnosis, treatment, and vector control.

Banner

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850mm wide x 2000 mm tall

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The promotional video for The Lancet Commission on malaria eradication is two and a half minutes long, and provides a compelling look at the history of the malaria fight and what is needed to eradicate the disease within a generation.

Video

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The Lancet Commission on malaria eradication Advocacy & Communications Toolkit | 11www.malariaeradicationcommission.com

Events

The enclosed assets are intended to be used to promote the Commission’s findings at numerous opportunities in the months following the initial publication of the full report.

Rising to the Challenge of Malaria EradicationWorld Health Organization, Geneva, Switzerland

Monday, 9 September 2019 from 1:30pm – 6pm

Malaria Eradication within a Generation: Ambitious, Achievable and NecessaryRoyal Academy of Engineering, London, UK

Thursday, 12 September 2019 from 1:00pm – 5:15pm

Click here to livestream the London event

View program and register to attend

Malaria Eradication within a Generation: Ambitious, Achievable and NecessaryCenter for Strategic & International Studies, Washington DC, United States

Wednesday, 18 September 2019 from 2:00pm – 4:00pm

Malaria Eradication within a Generation: Ambitious, Achievable and NecessaryUniversity of California, San Francisco, United States

Thursday, 26 September 2019 from 1:00pm – 4:00pm

Malaria Eradication within a Generation: Ambitious, Achievable and NecessaryLee Kuan Yew School of Public Policy, Singapore

Tuesday, 8 October 2019 from 2:00pm – 5:00pm

For the most current list of events, please visit: malariaeradicationcommission.com/news-events/events

Please consider helping us to promote the Commission’s findings on social media during any of these events using

#LancetMalaria #EndMalaria #malariaeradication

Can’t join us for an event in person? Listen in to the livestream of the London event

Thursday, September 12 from 1.30 pm UK time

malariaeradicationcommission.com/news-events/events/londonlivestream

LIVE STREAM