Pharmacology Key Answers الفصل الاول تمريض

8/7/2019 Pharmacology Key Answers

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Pharmacology - Reviewed QuestionsPrinciples of Pharmacology

**Choose the best answer:(1) Pharmacology is the study of:

(A) Plants(B) Cars(C) Drugs(D) Computers

(2) Drug is a substance that affect:(A) Living processes(B) Cars(C) Pens(D) Books

(3) Therapeutics is the medical use of:(A) Plants

(B) Drugs(C) Books(D) Viruses

(4) Pharmacokinetics is the way by which the body deal with:(A) Drugs(B) Mouth(C) Kidney(D) Stomach

(5) Pharmacokinetics include the following:(A) Absorption & Metabolism & Distribution & Excretion(B) Absorption only(C) Distribution only(D) Metabolism only

(6) Pharmacodynamic is defined as effect of the drug on the:(A) Car (B) Book(C) Body


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Nursing Department/ Second Level Pharmacology

(C) Provide maximum benefit with maximum harm(D) Provide no benefit with maximum harm

(14) The abbreviation PDR refers to:(A) Physician Desk Reference(B) Physiology Desk Reference(C) Physician Drug Reference(D) Physician Desk Record

(15) Drug information can be obtained from:(A) Published References & Nursing journals & Textbooks

(B) Textbooks only(C) Nursing journals only(D) PDR only

(16) Pharmacology is important for nursing for reasons of:(A) Patient care and education(B) Physician care(C) Pharmacist education(D) Dentist care

(17) Pharmacological knowledge helps the nurse to:(A) Minimize adverse effects & interactions(B) Maximize adverse effects(C) Maximize drug interactions(D) Maximize toxicity

(18) A drug may produce its effects through:(A) Physical and chemical action(B) Regulatory proteins(C) A & B(D) A only

(19) Osmotic diuretics and purgatives act by:(A) Osmosis(B) Oxidation(C) Reduction(D) Polymorphism

(20) Activated charcoal acts by:(A) Adsorption of toxins(B) Osmosis

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(C) Oxidation(D) Polymorphism

(21) Antacids (NaHCO 3) neutralize:(A) Gastric acidity(B) Gastric alkalinity(C) Eye acidity(D) Nasal acidity

(22) Chelating agents (e.g. Dimercaprol) form inactive complexes with:(A) Mercury & Arsenic & Gold

(B) NaCl(C) KCl(D) NaOH

(23) Examples of enzyme inhibitors are:(A) Cimetidine(B) Phenytoin(C) Phenpbarbitone(D) Smoking

(24) Examples of enzyme inducers are:(A) Phenpbarbitone & Phenytoin & Nicotine(B) Cimetidine(C) Paracetamol(D) Aspirin

(25) Local anesthetics block:(A) Na channels(B) Iron channels(C) Phosphate channels(D) Magnesium channels

(26) Agonist is a substance that:(A) Activates the receptor (B) Blocks the receptor (C) Inhibits the receptor (D) Destroys the receptor

(27) Antagonist is a substance that:(A) Blocks the receptor (B) Activates the receptor

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(C) Has no effect on the receptor (D) Activates the stomach

(28) Reversible (Competitive) antagonists make:(A) Weak bonds with the receptor (B) Strong bonds with receptor (C) No bonds with receptors(D) Very strong bonds with the receptor

(29) Irreversible (non-competitive) antagonists form:(A) Weak bonds with the receptor

(B) Strong bonds with receptor (C) No bonds with receptors(D) Very weak bonds with the receptor

(30) Drugs interaction before administration is called:(A) Pharmaceutical incompatibility(B) Pharmacokinetics incompatibility(C) Pharmacodynamic incompatibility(D) Pharmaceutical compatibility

(31) Heparin solutions form chemical complexes with:(A) Benzylpenicillin & Gentamycin & Hydrocortisone(B) Paracetamol(C) Aspirin(D) Enzymes

(32) Dextran solutions form complexes with:(A) Ampicillin & Barbiturates & Ascorbic acid(B) Ampicillin only(C) Barbiturates only(D) Ascorbic acid only

(33) Adrenaline decrease the absorption of local anesthetics due to:(A) Vasoconstriction(B) Vasodilatation(C) Osmosis(D) Oxidation

(34) Drug interaction after drug administration is called:(A) Pharmacokinetic or Pharmacodynamic(B) Pharmaceutical incompatibility

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(C) Pharmacology(D) Nursing

(35) Tetracycline forms insoluble complexes with:(A) Ca ++ & Mg ++ & Al +++ (B) Dextrose(C) Ca ++ only(D) Mg ++ only

(36) Salicylates absorption is:(A) Decreased by antacids

(B) Increased by antacids(C) Not change by antacids(D) Increases by methanol

(37) Anti-cholinergics:(A) Decrease intestinal motility(B) Increase absorption of some drugs(C) A & B(D) Increase intestinal motility

(38) Fatty meal increase the absorption of:(A) Lipid soluble drugs(B) Water soluble drugs(C) Water (D) Lipid insoluble drugs

(39) Phenylbutazone displaces warfarin from plasma proteins and resultsin:

(A) Excessive bleeding(B) Blood clotting(C) Influenza(D) Hepatitis B

(40) MAO inhibitors decrease the metabolism of some drugs like:(A) Norepinephrine & Barbiturates & Benzodiazepines(B) Norepinephrine only(C) Serotonin only(D) Barbiturates only

(41) Probenecid decrease the absorption of:(A) Penicillin & Indomethacin & Methotrexate

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(B) Penicillin only(C) Indomethacin only(D) Methotrexate

(42) Aspirin decreases the excretion of:(A) Methotrexate(B) Water (C) Methanol(D) Dextrose

(43) Urine alkalinization is done by:

(A) Sodium bicarbonate(B) Acetic acid(C) HCL(D) H 2SO 4

(44) Urine alkalinization increases excretion of:(A) Weak acids(B) Weak bases(C) Weak acids and bases(D) NaOH

(45) Urine acidification is done by the use of:(A) Sodium bicarbonate(B) Ammonium chloride(C) NaOH(D) KOH

(46) Urine acidification increases the excretion of:(A) Weak acids(B) Weak bases(C) HCL(D) H 2SO 4

(47) Cisplatin toxicity can be reduced by:(A) Mannitol (B) Aspirin(C) Paracetamol(D) Ketoprofen

(48) Phenobarbital:(A) Increase biliary secretion of many drugs

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(B) Decrease biliary secretion of many drugs(C) Has no effect on biliary secretion(D) Increase nasal secretion of drugs

(49) Synergism effect of two drugs is:(A) Lower than the sum of their effects(B) Greater than the sum of their effects(C) Equal to the sum of their effects(D) Lower than one of them

(50) An example of additive drug interaction is:

(A) Aspirin & Paracetamol (B) Aspirin only(C) Paracetamol only(D) Adrenaline only

(51) Canceling effect of one drug by another is called:(A) Potentiation(B) Antagonism(C) Synergism(D) Addition

(52) Antagonism is classified as:(A) Physical, Chemical, Physiological and Pharmacological (B) Physical only(C) Chemical only(D) Physiological only

(53) Activated charcoal is used in treatment of (A) Alkaloid toxicity(B) Hypertension(C) Allergy(D) Hypotension

(54) An example of physiological antagonism is:(A) Histamine & Adrenaline(B) Histamine & Activated charcoal(C) Histamine & Water (D) Adrenaline & Paracetamol

(55) Schedule I of controlled substances includes:(A) Heroin

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(B) Paracetamol(C) Aspirin(D) Codeine

(56) Schedule II of controlled substances includes:(A) Heroin(B) Paracetamol(C) Morphine(D) Codeine

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Administration of Medications

**Choose the best answer:(1)Nurse is responsible for:

(A) Safe administration of medication(B) Unsafe administration of medication(C) Bad administration of medication(D) Drug manufacture

(2)You have a 10 ml vial of aminophylline labeled 25 mg per ml. Howmany milliliters must be injected to administer a dose of 125 mg?

(A) 2 ml(B) 5 ml (C) 7 ml

(D) 8 ml

(3)Clarks rule is used to calculate:(A) Child dose(B) Hospital area(C) Pharmacy area(D) Faculty area

(4)The parentral dose of erythromycin injection is 10mg/Kg/24 h.

Calculate the daily dose of this drug for a 20 Kg child.(A) 200 mg/24 h(B) 200 g/24 h(C) 200 Kg/24 h(D) 20 mg/24 h

(5)1 g equals to:(A) 100 mg(B) 1000 mg(C) 10000 mg(D) 10 mg

(6)300 mg equals to:(A) 3 g(B) 0.3 g(C) 30 g(D) 0.03 g

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(7)1 gr equals to:(A) 65 mg(B) 650 mg(C) 0.65 mg(D) 0.56 mg

(8)1 tbsp. equals to:(A) 10 ml(B) 15 ml (C) 20 ml(D) 25 ml

(9)-49 F equals to:(A) 99 C

(B) 9 C(C) -45 C(D) 88 C

(10) The five rights of drug administration are:(A) Right (Patient & Drug & Dose)(B) Right (Route & Time)(C) A & B(D) A only

(11) The abbreviation (b.i.d.) means:(A) Once daily(B) Two times daily(C) Three times daily(D) Four times daily

(12) The abbreviation (q3h) means:(A) Every 4 hours(B) Every 3 hours(C) Every 2 hours(D) Every 8 hours

(13) The abbreviation (IM) means:(A) Capsules(B) Intravenous(C) Intramuscular (D) Tablets

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(14) The abbreviation (P.O.) means:(A) By mouth(B) By rectum(C) By vagina(D) By inhalation

(15) The order (Tab. II Stat. then tab. I b.i.d.) means:(A) 2 tablets at once then 1 tablet twice a day(B) 1 tablets at once then 2 tablet twice a day(C) 3 tablets at once then 4 tablet twice a day(D) 2 tablets at once then 1 tablet three times a day

(16) The order (2 ml IM Stat. & q12h)(A) 2 ml intramuscularly at once and every 12 hour

(B) 1 ml intramuscularly at once and every 22 hour (C) 4 ml intramuscularly at once and every 12 hour (D) 2 ml intramuscularly at once and every 2 hour

(17) Using oral route, drugs are administered by:(A) Mouth(B) Ear (C) Eye(D) Rectum

(18) Sub-lingual route has the advantage of:(A) Bypassing the gastrointestinal tract(B) Bypassing the heart(C) Bypassing the kidney(D) Bypassing the blood

(19) Parentral products are:(A) Sterile(B) Non-sterile(C) Have many living microorganisms(D) Have some microorganisms

(20) Rectal route is suitable for:(A) Unconscious or vomiting patients(B) Children(C) A & B(D) A only

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Drugs Affecting Central Nervous System

**Choose the best answer:(1)General anesthetics produce:

(A) Loss of conscious & Analgesia(B) Muscle relaxation(C) A & B(D) B only

(2)An example of inhalation anesthetic is:(A) Halothane & Ether & Nitrous oxide(B) Halothane only(C) Ether only(D) Aspirin

(3)Thiopental is an example of:(A) Intravenous anesthetic(B) Inhalation anesthetic(C) NSAIDs(D) Antiemetics

(4)Local anesthetics produce the following effects:(A) Blocking of nerve conduction

(B) Localized loss of sensation(C) A & B(D) A only

(5)Lidocaine is an example of:(A) Local injection anesthetic drug(B) Topical anesthetic drug(C) A & B(D) Antiemetics

(6) Sedatives (Antianxiety) are drugs that:(A) Reduce anxiety and cause calm(B) Increase anxiety(C) Do not cause calm(D) Increase blood pressure

(7)Drugs that encourage sleep are called:(A) Hypnotics(B) Antibiotics(C) Antacids(D) Hypoglycemic drugs

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(8)An example of long acting barbiturates:(A) Phenobarbital(B) Aspirin(C) Paracetamol(D) Lidocaine

(9)Diazepam is an example of:(A) Short acting benzodiazepines(B) Intermediate acting diazepines(C) Long acting diazepines(D) Antacids

(10) Antiepileptics include the following except:(A) Primdone & Ethosuximide

(B) Phenytoin & Valproic acid(C) Carbamazepine(D) Paracetamol

(11) Parkinsonism is due to:(A) Aspirin deficiency(B) Paracetamol deficiency(C) Dopamine deficiency(D) Ketoprofen deficiency

(12) L-dopa (Levodopa) is an example of:(A) Dopaminergic drugs(B) NSAIDs(C) Antibiotics(D) Antacids

(13) Chlorpromazine is an example of:(A) Antipsychotic(B) NSAIDs(C) Antibiotics(D) Antacids

(14) Clozapine is an example of:(A) Antipsychotic(B) NSAIDs(C) Antibiotics(D) Antacids

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(15) Antidepressants include the following except:(A) Amitriptyline(B) Imipramine(C) Fluxetine(D) Declofenac

(16) Lithium is used as:(A) Antacid(B) Antiemetic(C) Antimania(D) Antibiotic

(17) Psychomotor stimulants include the following except:(A) Amphetamine

(B) Xanthine(C) Dextroamphetamine(D) Paracetamol

(18) Side effects of narcotics include:(A) Euphoria(B) Respiratory depression(C) A & B(D) Diarrhea

(19) Morphine is used as analgesic in:(A) Severe pain(B) Diarrhea(C) Asthma(D) Weak pain

(20) Codeine is used as:(A) Antiemetic(B) Antitussive(C) Antacid(D) Antibiotic

(21) Loperamide is used to control(A) Hypertension(B) Hypotension(C) Diarrhea(D) Constipation

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(22) Acute attack of migraine is treated by:(A) Ergotamine & Sumatriptan(B) Ranitidine(C) Levodopa(D) Amoxicillin

(23) Migraine prophylaxis is achieved by the use of:(A) Cyproheptadine & Propranolol (B) Cefadroxil(C) Famotidine(D) Loperamide

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Drugs Affecting Autonomic Nervous System

**Choose the best answer:(1)Catecholamines include the following:

(A) Adrenaline & Noradrenaline & Dobutamine(B) Isoprenaline only(C) Aspirin(D) Paracetamol

(2)( 1 & 2 & 1 & 2) mixed agonists include:(A) Epinephrine(B) Paracetamol(C) Declofenac(D) Ampicillin

(3)Mainly alpha agonists include:(A) Norepinephrine(B) Paracetamol(C) Aspirin(D) Salbutamol

(4)Cardiac arrest is treated by:(A) Adrenaline

(B) Aspirin(C) Amoxicillin(D) Ampicillin

(5)Noradrenaline is used to treat:(A) Hypertension(B) Hypotension(C) Tonsillitis(D) Headache

(6)Shock is treated by:(A) Dopamine & Dobutamine(B) Paracetamol(C) Aspirin(D) Salbutamol

(7)Bronchodilators are used in:(A) Bronchial asthma(B) Hypertension(C) Hypotension(D) Headache

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(8)Bromocryptine is used in treatment of:(A) Parkinsonism(B) Hypertension(C) Hypotension(D) Tonsillitis

(9)Side effects of prazosin includes;(A) Syncope(B) Cancer (C) Hypertension(D) Liver disease

(10) Prazosin is used in treatment of:(A) Hypertension

(B) Urine retention(C) A & B(D) Headache

(11) Pilocarpine is used in treatment of:(A) Glaucoma(B) Tonsillitis(C) Renal failure(D) Infection

(12) Antidote used in curare toxicity is:(A) Neostigmine(B) Paracetamol(C) Aspirin(D) Pilocarpine

(13) Adverse effects of parasympathomimetics include:(A) Miosis & Diarrhea & Excessive sweating(B) Miosis only(C) Diarrhea only(D) Constipation

(14) Benztropine is used as:(A) Antacid(B) Antiparkinsonian(C) Anti-emetic(D) Antibiotic

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(15) Skeletal muscle relaxants:(A) Reduce muscle tone(B) Increase muscle tone(C) Has no effect on muscle tone(D) Increase blood pressure

(16) An example of centrally acting skeletal muscle relaxants is:(A) Diazepam(B) Curare(C) Paracetamol(D) Aspirin

(17) Skeletal muscle relaxants has many adverse effects:(A) Respiratory paralysis

(B) Hypotension(C) A & B(D) Bronchospasm only

(18) Orphenadrine & Clorzoxazone are:(A) Centrally acting skeletal muscle relaxants(B) Antacids(C) Antiemetics(D) Antibiotics

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Drugs Affecting Cardio-vascular System

**Choose the best answer:(1)Clinical uses of furosemide include:

(A) Hypertension & Pulmonary edema(B) Headache(C) Tonsillitis(D) Peptic ulcer

(2)Adverse effects of furosemide include:(A) Ototoxicity & Hyperglycemia(B) Hypoglycemia(C) Hypernatremia(D) Hyperkalemia

(3)Thiazides include:(A) Chlorothiazide(B) Ampicillin(C) Amoxicillin(D) Aspirin

(4)Which of the following are used in hypertension?(A) Thiazides

(B) Adrenaline(C) Noradrenaline(D) Paracetamol

(5)Spironolactone is used in treatment of:(A) Hyperaldosteronism(B) Headache(C) Gastric ulcer (D) Fever

(6)Antihypertensive drugs are used in the treatment of:(A) Hypertension(B) Hypotension(C) Headache(D) Fever

(7)Non-selective beta blocker includes(A) Propranolol (B) Atenolol(C) Aspirin(D) Adrenaline

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(8)Adverse effects of verapamil are:(A) Heart failure & Constipation(B) Peptic ulcer (C) Diarrhea(D) Pharengitis

(9)An example of ACEIs:(A) Captopril (B) Calcium(C) Carbon(D) Adrenaline

(10) Adverse effects of captopril are:(A) Cough & Fetal renal damage & Hypotension

(B) Hypertension(C) Hyperacidity(D) Eye congestion

(11) Minoxidil & nitroprosside are:(A) Vasodilator (B) Vasoconstrictor (C) Antacid(D) Antiemetic

(12) Antihypertensives used in heart failure are:(A) ACEIs(B) NSAIDs(C) Antibiotics(D) Paracetamol

(13) Parentral therapy of hypertension includes:(A) Diuretics (Furosemide)(B) Beta blocker (Propranolol(C) A & B(D) Aspirin

(14) Digoxin is used in treatment of:(A) Heart failure(B) Asthma(C) Headache(D) Gastric ulcer

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(15) Adverse effects of digoxin includes:(A) Arrhythmias & Nausea & Vomiting(B) Peptic ulcer (C) Nausea only(D) Vomiting only

(16) Arrhythmias can be treated by:(A) Quinidine & Atenolol (B) Aspirin(C) Paracetamol(D) Adrenaline

(17) Adverse effects of quinidine include:(A) Cinchnism

(B) Tonsillitis(C) Gastritis(D) Acne Vulgaris

(18) Acute attack of angina is treated by:(A) Nitroglycerin(B) Adrenaline(C) Noradrenaline(D) Dopamine

(19) Adverse effects of nitrates are:(A) Orthostatic hypotension & Tachycardia(B) Otitis media(C) Colic(D) Peptic ulcer

(20) Hyperlipidemia is a condition of high level of:(A) Cholesterol & Triglycerides(B) Adrenaline(C) Dopamine(D) Aspirin

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Drugs Acting on the Digestive System

**Choose the best answer:(1)Cimetidine & Ranitidine are used in the treatment of:

(A) Headache(B) Gastric ulcer (C) Allergy(D) Diarrhea

(2)Gynecomastia & Galactorrhea are occurred due to use of:(A) Cimetidine(B) Ranitidine(C) Aspirin(D) Amoxicillin

(3)Omeprazole is an example of:(A) H 2 receptor antagonist(B) Proton pump inhibitor (C) H 1 receptor inhibitor (D) Anti-emetic

(4)An example of antacids is:(A) NaHCO 3

(B) Al(OH) 3(C) A & B(D) Aspirin

(5)Drugs that protect gastric mucosa include:(A) Sucralfate(B) Atenolol(C) Propranolol(D) Cimetidine

(6)Misoprostol is contraindicated in childbearing women because it is:(A) Abortifacient(B) Safe(C) Expensive(D) Cheap

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(7)Triple therapy of helicobacter pylori oncludes:(A) Proton pump inhibitor (B) Clarithromycin & Amoxicillin(C) A & B(D) Omeprazole only

(8)Emetics are drugs that induce:(A) Vomiting(B) Constipation(C) Diarrhea(D) Bleeding

(9)An example of emetics is:(A) Ipecac syrup

(B) Apomorphine(C) A & B(D) Ketoprofen

(10) Antiemetics are drugs that:(A) Prevent emesis(B) Induce emesis(C) Prevent constipation(D) Prevent bleeding

(11) Metoclopramide is used as:(A) Antiemetic(B) Antibiotic(C) Antacid(D) Purgative

(12) Vitamin B 6 is used to treat:(A) Headache(B) Allergy(C) Vomiting of pregnancy(D) Tonsillitis

(13) Purgatives are used in the treatment of:(A) Constipation(B) Diarrhea(C) Headache(D) Pain

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(14) Lactulose & Castor oil are examples of:(A) Purgatives(B) ACEIs(C) NSAIDs(D) Acids

(15) Adverse effects of castor oil include:(A) Dehydration & Abortion in pregnant women(B) Peptic ulcer (C) Dehydration only(D) Acne Vulgaris

(16) Prokinetics are drugs that:(A) Increase gastrointestinal motility

(B) Decrease gastrointestinal motility(C) Cause headache(D) Cause renal stone

(17) Examples of prokinetics are:(A) Domperidone & Metoclopramide(B) Aspirin(C) Paracetamol(D) Ketoprofen

(18) Anti-diarrheals are used in treatment of:(A) Constipation(B) Diarrhea(C) Headache(D) Angina Pectoris

(19) Loperamide, kaolin and pectin can be used in the treatment of:(A) Headache(B) Diarrhea(C) Hypertension(D) Hypotension

(20) Antispasmodics are drugs that used in treatment of:(A) Colonic spasm(B) Headache(C) Fever (D) Allergy

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(21) Adverse effects of atropine includes:(A) Constipation & Urine retention & Dry mouth(B) Constipation only(C) Fever (D) Allergy

(22) Mebeverine is used as:(A) Smooth muscle relaxants(B) Antacid(C) Antibiotic(D) Antiemetic

(23) Antiflatulents are used to alleviate:(A) Meteorism

(B) Allergy(C) Diarrhea(D) Fever

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Drugs Acting on the Respiratory System

**Choose the best answer:(1)Bronchial asthma is a obstruction of:

(A) Airway(B) Brain(C) Kidney(D) Stomach

(2)Non-selective agonists include:(A) Adrenaline & Isoprenaline(B) Atenolol(C) Propranolol(D) Paracetamol

(3)Salbutamol & Terbutaline are:(A) Non-selective agonists(B) Selective agonists(C) Non selective antagonists(D) selective antagonists

(4)Salbutamol is used in the treatment of:(A) Bronchial asthma

(B) Headache(C) Fever (D) Diarrhea

(5)Theophylline can be used in the treatment of:(A) Bronchial asthma(B) Headache(C) Fever (D) Diarrhea

(6)Beclomethasone can be used in the treatment of:(A) Acute bronchial asthma(B) Headache(C) Peptic ulcer (D) Hypertension

(7)Antitussives are used in the treatment of:(A) Dry cough(B) Productive cough(C) Fever (D) Constipation

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(8)Peripheral anti-tussives include:(A) Liquorice lozenges(B) Steam inhalation(C) A & B(D) Codeine

(9)Codeine & Pholcodeine are:(A) Peripheral anti-tussives(B) Central antitussives(C) Antacids(D) Antibiotics

(10) Guaifenesin is:(A) Expectorants

(B) Antiemetics(C) Antacids(D) Antibiotics

(11) Bromhexine & Ambroxol are examples of:(A) Mucolytics(B) Antiemetics(C) Antacids(D) Antibiotics

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Drugs Affecting the Endocrine System

**Choose the best answer:(1)GHRH stimulate the release of:

(A) Prolactin(B) Growth hormone(C) Adrenaline(D) Thyroxin

(2)GH stimulates:(A) Growth of the body(B) Death(C) Book(D) Adrenaline

(3)T 3 & T4 are secreted from:(A) Thyroid gland(B) Pituitary gland(C) Stomach(D) Kidney

(4)Thyroid hormone antagonists are used in:(A) Hyperthyroidism

(B) Hypothyroidism(C) Peptic ulcer (D) Diarrhea

(5)An example of thyroid hormone antagonists is:(A) Carbimazole & Propylthiouracil (B) Aspirin(C) Paracetamol(D) Nicotine

(6)Synthetic glucocorticoides include:(A) Prednisolone & Cortisone(B) Paracetamol(C) Adrenaline(D) Thyroxine

(7)Clinical uses of steroids include:(A) Addisons disease(B) Bronchial asthma(C) A & B(D) Peptic ulcer

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(8)Adverse effects of glucocorticoides include:(A) Hyperglycemia & osteoporosis(B) Hypertension(C) A & B(D) Hypotension

(9)Steroid synthesis inhibitors include:(A) Ketoconazole(B) Spironolactone(C) A & B(D) Aspirin

(10) Type I DM is due to:(A) Insulin deficiency

(B) Insulin resistance(C) Headache(D) Bleeding

(11) Insulin is usually administered by:(A) Intra-arterial route(B) Intra-cardiac route(C) Subcutaneous route(D) Intra-thecal route

(12) Insulin deficiency results in:(A) Hyperglycemia(B) Hypoglycemia(C) Hypertension(D) Hypotension

(13) Adverse effects of insulin therapy includes:(A) Hypoglycemic coma(B) Weight gain(C) A & B(D) Tonsillitis

(14) Oral hypoglycemic agents stimulate secretion:(A) Insulin(B) Adrenaline(C) Thyroxine(D) Calcitonin

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(15) Oral hypoglycemic drugs:(A) Tolbutamide(B) Gliclazide(C) A & B(D) Paracetamol

(16) Metformin is:(A) Oral hypoglycemic drug(B) Oral analgesic drug(C) Oral anti-pyretic drug(D) Oral anti-steroidal drug

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Drugs Affecting the Reproductive System

**Choose the best answer:(1)Ethinyl estradiol is used in:

(A) Contraception & Female gonadism(B) Headache(C) Peptic ulcer (D) Constipation

(2)Tamoxifen is used in treatment of:(A) Metastatic cancer (B) Headache(C) Peptic ulcer (D) Constipation

(3)Medroxyprogestron is used in:(A) Contraception(B) Headache(C) Peptic ulcer (D) Constipation

(4)Mifepristone is used as:(A) Abortifacient

(B) Antacid(C) Antibiotic(D) Antipyretic

(5)An example of parentral contraception is:(A) Paracetamol(B) Aspirin(C) Medroxyprogestrone(D) Adrenaline

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Drugs Affecting the Immune System

**Choose the best answer:(1)Immunosuppressive agents include:

(A) Cyclosporine(B) Azathioprine(C) A & B(D) Aspirin

(2)Cyclosporine toxicity includes:(A) Nephrotoxicity & Hypertension(B) Headache(C) Peptic ulcer (D) Hypertension only

(3)Azathioprine is used in:(A) Kidney transplantation(B) Hemolytic anemia(C) A & B(D) Gastric ulcer

(4)Azathioprine toxicity includes:(A) Bone marrow depression

(B) Increase risk of infection(C) A & B(D) Decrease risk of infection

(5)Immunostimulating agents stimulate:(A) Immune response(B) Growth(C) Death(D) Synthesis of adrenaline

(6)Levamisole can be used in treating:(A) Chronic infections(B) Headache(C) Glaucoma(D) Thyrotoxicosis

(7) IFN- is used in treatment of:(A) Chronic hepatitis B & C(B) Renal failure(C) Headache(D) Peptic ulcer

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(8)IFN- is used in treatment of:(A) Multiple sclerosis(B) Headache(C) Renal failure(D) Peptic ulcer

(9)INF- is used in treatment of:(A) Chronic granulomatous disease(B) Renal failure(C) Headache(D) Peptic ulcer

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Other Pharmacological Groups

**Choose the best answer:(1)Antimicrobial agents are substances that:

(A) Kill or inhibit microorganism growth(B) Stimulate microorganism growth(C) Cause peptic ulcer (D) Cause infection

(2)Bactericidal agents:(A) Kill infecting organism(B) Stimulate microorganism growth(C) Cause peptic ulcer (D) Cause infection

(3)Quinolones are used in the treatment of:(A) Urinary tract infections(B) Meningitis(C) A & B(D) Headache

(4) Quinolones are contraindicated in:(A) Pregnancy & Children

(B) Adults(C) Pregnancy only(D) Children only

(5)Sulfonamides inhibit:(A) Bacterial folic acid pathway(B) Thyroxine synthesis(C) Adrenaline synthesis(D) Vitamin K synthesis

(6)Sulphonamides are used in the treatment of:(A) Urinary tract infection(B) Meningitis(C) A & B(D) Headache

(7)Co-trimoxazole is used in the treatment of:(A) Typhoid fever (B) Allergy(C) HIV(D) HSV

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(15) Which drug is used in the treatment of cholera:(A) Tetracycline(B) Paracetamol(C) Castor oil(D) Paraffin oil

(16) Tetracyclines are contraindicated in:(A) Pregnancy & Children(B) Adults(C) Cholera(D) Typhus

(17) An example of macrolides is:(A) Erythromycin & Clarithromycin

(B) Paracetamol(C) Aspirin(D) Ibuprofen

(18) Adverse effects of isoniazid are:(A) Peripheral neuropathy & Optic neuritis(B) TB(C) Dehydration(D) Constipation

(19) Rifampin is used in the treatment of:(A) TB(B) Gastritis(C) Constipation(D) Eye congestion

(20) Rifampin color body fluids with:(A) Red/orange color (B) Green color (C) Black color (D) White color

(21) Second line drugs used in tuberculosis are:(A) Cycloserine & PAS(B) Paracetamol(C) Aspirin(D) Ranitidine

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(22) Leprosy is treated by the use of:(A) Dapson & Clofamizine & Rifampin(B) Paracetamol(C) Aspirin(D) Ranitidine

(23) Disinfection refers to:(A) Killing of pathogens in human(B) Stimulation of pathogens(C) Drug administration(D) Drug adverse effects

(24) Sterilization refers to killing of:(A) All microorganisms

(B) Pathogenic microorganisms(C) Non-pathogenic microorganisms(D) Animals

(25) An example of antiseptics is:(A) Phenols & 70 % ethanol (B) 10 % ethanol(C) 15 % ethanol(D) 20 % ethanol

(26) Antifungals are used in the treatment of:(A) Fungal infection(B) Bacterial infection(C) Viral infection(D) Headache

(27) Antifungals include:(A) Fluconazole & Ketoconazole & Miconazole(B) Paracetamol(C) Aspirin(D) Amoxicillin

(28) Adverse effects of griesofulvin include:(A) Hepatotoxicity & Teratogenicity(B) Bleeding(C) Parkinsonism(D) CHF

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(29) Fluocytosin is used in the treatment of:(A) Systemic mycosis & Fungal meningitis(B) Headache(C) Peptic ulcer (D) Bone marrow depression

(30) Anti-herpes virus agents include:(A) Acyclovir & Ganciclovir (B) Ranitidine(C) Rifampin(D) Fluocytosin

(31) Anti-retroviral agents are used in the treatment of:(A) HIV infection

(B) Headache(C) Peptic ulcer (D) Bone marrow depression

(32) Zidovudine is used as:(A) Anti-viral (B) Anti-bacterial(C) Analgesic(D) Antifungal

(33) Amantadine is used in:(A) Prophylaxis of influenza A(B) Prophylaxis of peptic ulcer (C) Prophylaxis of headache(D) Prophylaxis of malaria

(34) Vaccines are weapons to:(A) Prevent disease(B) Aid contamination(C) Prevent headache(D) Prevent drug toxicity

(35) Viral live attenuated vaccines include:(A) Measles & Mumps(B) Amoxicillin(C) Ampicillin(D) Cefadroxil

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(36) Bacterial live attenuated vaccines include:(A) Tuberculosis(B) Amoxicillin(C) Ampicillin(D) Cefadroxil

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Anti-inflammatory Agents

**Choose the best answer:(1)Pharmacological effects of NSAIDs include:

(A) Analgesic & Antipyretic & Anti-inflammatory(B) Ant-hypertensive(C) Anti-bacterial effect(D) Anti-viral effect

(2)Adverse effect of aspirin include:(A) Gastritis & Ulcer (B) Hypertension(C) Hypotension(D) Tonsillitis

(3)Non-selective cox-inhibitor includes:(A) Indomethacin & Declofenac(B) Celecoxib(C) Rofecoxib(D) Ranitidine

(4)N-acetylcysteine is used in the treatment of:(A) Paracetamol overdose

(B) Aspirin overdose(C) Amoxicillin overdose(D) Ampicillin overdose

(5)Acute attack of gout is treated by:(A) Colchicine & Allopurinol & Probenecid(B) Paracetamol(C) Allopurinol only(D) Amphotericin B

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Anti-neoplastic Agents

**Choose the best answer:(1)Cancer chemotherapy consists of drugs that used in the treatment of:

(A) Cancer (B) Influenza(C) Peptic ulcer (D) Constipation

(2)Palliative therapy of cancer attempts to:(A) Slow tumor growth(B) Eliminate all malignant cells(C) Increase tumor growth(D) Induce cancer

(3)Agents used in cancer include:(A) Methotrexate & 5-FU(B) Aspirin(C) Paracetamol(D) Ranitidine

(4)Methotrexate toxicity includes:(A) Bone marrow suppression

(B) Peptic ulcer (C) Influenza(D) Diarrhea

(5)Cyclophosphamide is used in the treatment of:(A) Breast and ovarian carcinomas(B) Peptic ulcer (C) Influenza(D) Diarrhea

(6)Breast cancer is treated by:(A) Tamoxifen(B) Peptic ulcer (C) Influenza(D) Diarrhea

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(7) Vincristine is used in the treatment of:(A) Leukemias(B) Peptic ulcer (C) Influenza(D) Diarrhea

(8)Vinblastine toxicity include:(A) Bone marrow suppression & Alopecia(B) Peptic ulcer (C) Influenza(D) Diarrhea

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Pharmacology Key Answers الفصل الاول تمريض