Postgraduate Quiz

Instructions• All slides carry equal marks• There is no negative marking• Each slide will be given 30 seconds to 1 minute

after reading out the question

All the Best!

Q1.

• 18 years female presented with high grade fever• She was a known case of HIV

PBF• Identify the abnormality• Advice Cytochemistry

Q2.

• 48 years ♀ presented with weakness & variable cytopenias• She was being treated for depression

Trephine biopsy• Identify the abnormality• Advice Confirmatory test

Q3.

• 15 years male presented with fever with chills

PBF• Identify the abnormality• Name the Vector

Q4.

HPLC graph from BioRad Classic

• Identify the abnormality

• What will be the expected clinical phenotype?

Q5.

• Identify the preparation• Enumerate 2 conditions where the test may be positive

Q6.

64 year male with splenomegaly.• Interpret the flow cytometry• Suggest a molecular confirmatory test for this disease?

Q8.

Describe the morphology of the cell in the peripheral blood film.Mention 2 conditions where this can be seen

Q9.

A B

Normal Patient

Spot the abnormality

Name 2 conditions where the abnormality can be seen

Father (Case II)

Son (Case I )

?

Methemoglobin levels:

7.5% & after blood transfusion- 0.3%

OxyHb is capable of reversible oxygenation; its heme iron is in the reduced (or ferrous) stateMetHb: Heme oxidizes spontaneously & is incapable of reversible oxygenation

Q10.

• 21 years ♀ presented with gum bleeds & skin nodule• Blood counts showed increased TLC with thrombocytopenia

BM aspirate1. Suggest possible diagnosis2. Suggest associated

cytogenetic abnormality

Q6.• 2 year male presented with epistaxis• Coagulogram: PT- 13 sec, APTT-27 secs, N platelets

Platelet aggregation

Physiological Agonists ADP 10mMCollagen 2mg/ml Epinephrine 10mM Arachidonic acid 0.5mM

• What is the diagnosis?• What will you find in a finger prick smear• What is the mode of inheritance of the condition?

Q 10.

• Name any 2 agents that can be used for decalcification of bone marrow biopsies.

Q 11.

Kidney biopsy from a 33 yr female with seizures and acute renal failure following fever for a day.

• What is the diagnosis?• What will the PT & PTTK

results?• Mention one therapeutic

modality.

Two siblings ages 3 & 5 years presented with pallor and mild hemolytic faciesBM was done to investigate cause of anemia

Q 12.

BM aspirate

Descibe the BM findingsAny confirmatory tests?

Trephine biopsy

Q 13.

6 months child presented with progressive anemia and splenomegalyScreening for thalassemia was negative

Descibe the findingsAny special stains?

Q 14.• 13 yrs male presented with fever & echymosis for 3 days• Blood cell counts showed anemia, leucocytosis and thrombocytopenia

BM MPO

Describe the BM findings and interpret the MPO stain

Q 15.

Describe the BM aspirate finding