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Publikationen 2018

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Inhaltsverzeichnis Seite

Vorwort 3 Publikationen - Kardiologie 5

Publikationen - Herzchirurgie 19

Publikationen - Rheumatologie & Klinische Immunologie 23

- Physikalische Medizin & Osteologie

Publikationen - Thoraxchirurgie 31

Publikationen - Gefäßchirurgie & Angiologie 35

Publikationen - Labormedizin & Krankenhaushygiene 39

Publikationen - Rehabilitation & Psychokardiologie 43

Publikationen - Kerckhoff-Klinik Forschungsgesellschaft mbH 47

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Vorwort

Liebe Leserinnen und Leser,

es ist uns eine große Freude, Ihnen den Publikationsbericht 2018 der Kerckhoff-Klinik vorzulegen, welcher einen Einblick in die umfangreichen wissenschaftlichen und klinischen Forschungsaktivitäten auf nationaler und internationaler Ebene ermöglicht und dokumentiert. Hervorzuheben ist, dass die fächerübergreifenden Forschungs- und Publikationsthemen mit jeweils gleichrangiger Grundlagen- und Anwendungsorientierung auf höchstem Niveau realisiert wurden, was die ausgezeichnete wissenschaftliche Expertise widerspiegelt. Durch die Anbindung unserer Klinik an die Justus-Liebig-Universität Gießen und Gründung des Campus Kerckhoff im April 2018, bieten sich noch vielfältigere Möglichkeiten für Forschung und Lehre. So können u.a. internationale Wissenschaftler an der klinikeigenen Forschungseinrichtung, dem Franz-Groedel-Institut, unter optimalen Bedingungen wissenschaftlich arbeiten. Damit bieten wir einerseits einen entscheidenden Beitrag zur verbesserten Außenwirkung und Anerkennung von Wissenschaft und Forschung an unserem Campus Kerckhoff und andererseits ebnen wir dadurch für unsere Patienten eine hochqualitative ambulante wie stationäre Versorgung. Im Rahmen der wissenschaftlichen Netzwerkbildung ist die Verbindung zur Goethe-Universität Frankfurt/Main, die Zugehörigkeit der Kerckhoff-Klinik zum Exzellenz-Cluster Cardio Pulmonary System (ECCPS), die Zugehörigkeit zum Deutschen Zentrum für Herz-Kreislauf-Forschung (DZHK) e.V. als ein Standort des Zentrums, die Zugehörigkeit zum Sonderforschungsbereich 1213 „Pulmonale Hypertonie und Cor pulmonale“ der Deutschen Forschungsgemeinschaft (DFG) e.V., Rheumazentrum Hessen, The European Scleroderma Trials and Research Group, Deutsches Netzwerk für Systemische Sklerodermie, Myositis Netzwerk Hessen und European Reference Network on Rare and Complex Connective Tissue and Musculoskeletal Diseases zu erwähnen. Dank gebührt allen Beteiligten, die mit hohem Einsatz die wissenschaftliche Expertise am Campus Kerckhoff gestärkt und kontinuierlich fortgeführt und somit auch die Erstellung des Publikations-berichtes ermöglicht haben. Möge die engagierte Forschungsarbeit in den nächsten Jahren fortgesetzt werden, um die Expertise unseres Campus Kerckhoff weiter zu stärken. Mit freundlichen Grüßen, Ihre

Univ.-Prof. Dr. med. Uwe Lange Direktor Osteologie, Physikalische Medizin Stellv. Direktor Rheumatologie, klinische Immunologie Beauftragter für den Publikationsbericht Kerckhoff-Klinik GmbH

Univ.- Prof. Dr. med. Christian Hamm Ärztlicher Direktor Direktor Abt. Kardiologie der Kerckhoff-Klinik GmbH Direktor Forschung Direktor Med. Klinik I, Kardiologie des Universitätsklinikum Gießen

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Publikationen Herzzentrum Kardiologie Direktor: Univ.– Prof. Dr. med. C. Hamm

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Publikationen Herzzentrum Kardiologie Direktor: Univ.– Prof. Dr. med. C. Hamm

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PUBLIKATIONEN 2018 Originalarbeiten & Übersichtsartikel

1. Abtan J, Ducrocq G, Steg PG, Stone GW, Mahaffey KW, Gibson CM, Hamm C, Price MJ, Prats J, Elkin S, Deliargyris EN, White HD, Menozzi A, Harrington RA, Bhatt DL. Characteristics and out comes of patients requiring bailout use of glycoprotein IIb/IIIa inhibitors for thrombotic complications of percutaneous coronary intervention: An analysis from the CHAMPION PHOENIX trial. Int J Cardiol. 2018 Nov 23: In press. 2. Aghlmandi S, Scharer N, Heg D, Raber L, Zwahlen M, Gencer B, Nanchen D, Carballo D,Carballo S, Juni P, von Eckardstein A, Landmesser U, Rodondi N, Mach F, Windecker S, Matter CM, Lüscher TF, Klingenberg R. Thrombus aspiration in acute coronary syndromes: prevalence, pro cedural success, change in serial troponin T levels and clinical outcomes in a contemporary Swiss cohort. Eur Heart J Acute Cardiovasc Care. 2018 Sep; 7(6): 522-531. 3. Akkaya E, Berkowitsch A, Greiss H, Hamm CW, Sperzel J, Neumann T, Kuniss M. PLAAF score as a novel predictor of long-term outcome after second-generation cryoballoon pulmonary vein isolation. Europace. 2018 Nov 1; 20(Fi_3): f436-f443. 4. Akkaya E, Berkowitsch A, Zaltsberg S, Greiss H, Hamm CW, Sperzel J, Kuniss M, Neumann Five-year outcome and predictors of success after second-generation cryoballoon ablation for treatment of symptomatic atrial fibrillation. Int J Cardiol. 2018 Sep 1; 266: 106-111. 5. Akkaya E, Berkowitsch A, Zaltsberg S, Greiss H, Hamm CW, Sperzel J, Neumann T, Kuniss M. Second-generation cryoballoon ablation for treatment of persistent atrial fibrillation: Three-year outcome and predictors of recurrence after a single procedure. J Cardiovasc Electrophysiol. 2018 Jan; 29(1): 38-45. 6. Akkaya E, Berkowitsch A, Zaltsberg S, Greiss H, Hamm CW, Sperzel J, Neumann T, Kuniss M. Ice or fire? comparison of second-generation cryoballoon ablation and radiofrequency ablation in patients with symptomatic persistent atrial fibrillation and an enlarged left atrium. J Cardiovasc Electrophysiol. 2018 Dec 11; 29(3): 375-384. 7. Akkaya E, Berkowitsch A, Zaltsberg S, Greiss H, Hamm CW, Sperzel J, Neumann T, Kuniss M. Second-generation cryoballoon ablation as a first-line treatment of symptomatic atrial fibrillation: Two-year outcome and predictors of recurrence after a single procedure. Int J Cardiol. 2018 May 15; 259: 76-81. 8. Akkaya E, Berkowitsch A, Zaltsberg S, Greiss H, Hamm CW, Sperzel J, Neumann T, Kuniss M. Five-year experience with pulmonary vein isolation using the second-generation cryoballoon for treatment of persistent atrial fibrillation. J Cardiovasc Electrophysiol. 2018 Nov;29(11):1500- 1507. 9. Arsalan M, Kim WK, Van Linden A, Liebetrau C, Pollock BD, Filardo G, Renker M, Möllmann H, Doss M, Fischer-Rasokat U, Skwara A, Hamm CW, Walther T. Predictors and outcome of conversion to cardiac surgery during transcatheter aortic valve implantation. Eur J Cardiothorac Surg. 2018 Aug 1; 54(2): 267-272. 10. Arsalan M, Weferling M, Hecker F, Filardo G, Kim WK, Pollock B, Van Linden A, Arsalan-Werner A, Renker M, Doss M, Kalbas S, Liebetrau C, Hamm CW, Mack MJ, Walther T. TAVI risk scoring using established versus new scoring systems: role of the new STS/ACC model. EuroIntervention. 2018 Jan 20; 13(13): 1520-1526. 11. Bagai A, Goodman SG, Cantor WJ, Vicaut E, Bolognese L, Cequier A, Chettibi M, Hammett CJ, Huber K, Janzon M, Lapostolle F, Lassen JF, Merkely B, Storey RF, Ten Berg JM, Zeymer U, Diallo A, Hamm CW, Tsatsaris A, El Khoury J, Van't Hof AW, Montalescot G. Duration of ischemia and treatment effects of pre- versus in-hospital ticagrelor in patients with ST-segment elevation myocardial infarction: Insights from the ATLANTIC study. Am Heart J. 2018 Feb; 196: 56-64.^ 12. Baldus S, Kuck KH, Rudolph V, Nef H, Eggebrecht H, Boekstegers P, Wohrle J, Ince H, Möllmann H, Stellbrink C, Hausleiter J, von Bardeleben S, Kelm M, Elsässer A. Interventional therapy for AV valve disease-focus onmitral valve regurgitation. Position paper of the German Cardiac Society. Kardiologe. 2018 Apr; 12(2): 128-144. 13. Baquet M, Nef H, Gori T, Latib A, Capodanno D, Di Mario C, Sabate M, Colombo A, Tamburino C, Mehilli J. Restenosis patterns after bioresorbable vascular scaffold implantation: Angiographic substudy of the GHOST-EU registry. Catheter Cardiovasc Interv. 2018 Aug 1; 92(2): 276-282.

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13. Barvitenko N, Lawen A, Aslam M, Pantaleo A, Saldanha C, Skverchinskaya E, Regolini M, Tuszynski JA. Integration of intracellular signaling: biological analogues of wires, processors and memories organized by a centrosome 3D reference system. Biosystems. 2018; 173(Nov):191-206. 14. Bauer P, Henni S, Dörr O, Bauer T, Hamm CW, Most A. High prevalence of vitamin D insufficiency in professional handball athletes. Phys Sportsmed. 2018 Sep 10: In press. 15. Baumann S, Chandra L, Skarga E, Renker M, Borggrefe M, Akin I, Lossnitzer D. Instantaneous wave-free ratio (iFR((R))) to determine hemodynamically significant coronary stenosis: A comprehensive review. World J Cardiol. 2018 Dec 26; 10(12): 267-277. 16. Baumann S, Kryeziu P, Tesche C, Shuler DC, Becher T, Rutsch M, Behnes M, Stach K, Jacobs BE, Renker M, Henzler T, Haubenreisser H, Schoenberg SO, Weiss C, Borggrefe M, Schwemmer C, Schoepf UJ, Akin I, Lossnitzer D. Association of Serum Lipid Profile With Coronary Computed Tomographic Angiography-derived Morphologic and Functional Quantitative Plaque Markers. J Thorac Imag. 2018 Aug 23: In press. 17. Baumann S, Lossnitzer D, Renker M, Borggrefe M, Akin I. Coronary Computed Tomography Angiography-Derived Fractional Flow Reserve Assessment: Many Roads to Reach the Same Goal. Circ J. 2018 Jul 20; 82(9): 2448. 18. Baumann S, Renker M, Schoepf UJ. Coronary Computed Tomography-Based Fractional Flow Reserve: A Rapidly Developing Field. JAMA Cardiol. 2018 Nov 22; 3(1): 87. 19. Baumann S, Werner N, Ibrahim K, Westenfeld R, Al-Rashid F, Sinning JM, Westermann D, Schafer A, Karatolios K, Bauer T, Becher T, Akin I. Indication and short-term clinical outcomes of high-risk percutaneous coronary intervention with microaxial Impella(R) pump: results from the German Impella(R) registry. Clin Res Cardiol. 2018 Aug; 107(8): 653-657. 20. Baumann S, Werner N, Ibrahim K, Westenfeld R, Al-Rashid F, Sinning JM, Westermann D, Schafer A, Karatolios K, Bauer T, Becher T, Akin I. Indication and short-term clinical outcomes of high-risk percutaneous coronary intervention with microaxial Impella(R) pump: results from the German Impella(R) registry. Clin Res Cardiol. 2018 Aug; 107(8): 653-657.´ 21. Baumgartner H, Falk V, Bax JJ, Bonis M, Hamm C, Holm PJ, Iung B, Lancellotti P, Lansac E, Munoz DR, Rosenhek R, Sjogren J, Mas PT, Vahanian A, Walther T, Wendler O, Windecker S, Zamorano JL. [2017 ESC/EACTS Guidelines for the management of valvular heart disease]. Kardiol Pol. 2018 76(1): 1-62. 22. Baumgartner H, Falk V, Bax JJ, De Bonis M, Hamm C, Holm PJ, Iung B, Lancellotti P, Lansac E, Munoz DR, Rosenhek R, Sjogren J, Mas PT, Vahanian A, Walther T, Wendler O, Windecker S, Zamorano JL. 2017 ESC/EACTS Guidelines for the Management of Valvular Heart Disease. Rev Esp Cardiol (Engl Ed). 2018 Feb; 71(2): 110. 23. Becker J, Kinast V, Doring M, Lipps C, Duran V, Spanier J, Tegtmeyer PK, Wirth D, Cicin-Sain L, Alcami A, Kalinke U. Human monocyte-derived macrophages inhibit HCMV spread independent of classical antiviral cytokines. Virulence. 2018 9(1): 1669-1684. 24. Bekeredjian R, Szabo G, Balaban U, Bleiziffer S, Bauer T, Ensminger S, Frerker C, Herrmann E, Beyersdorf F, Hamm C, Beckmann A, Möllmann H, Karck M, Katus HA, Walther T. Patients at low surgical risk as defined by the Society of Thoracic Surgeons Score undergoing isolated interventional or surgical aortic valve implantation: in-hospital data and 1-year results from the German Aortic Valve Registry (GARY). Eur Heart J. 2018 Nov 16: In press. 25. Bergmark BA, Udell JA, Morrow DA, Cannon CP, Steen DL, Jarolim P, Budaj A, Hamm C, Guo J, Im K, Kuder JF, Braunwald E, Sabatine MS, O'Donoghue ML. Association of Fibroblast Growth Factor 23 With Recurrent Cardiovascular Events in Patients After an Acute Coronary Syndrome: A Secondary Analysis of a Randomized Clinical Trial. JAMA Cardiol. 2018 Jun 1; 3(6): 473-480. 26. Beygui F, Van Belle E, Ecollan P, Machecourt J, Hamm CW, Lopez De Sa E, Flather M, Verheugt FWA, Vicaut E, Zannad F, Pitt B, Montalescot G. Individual participant data analysis of two trials on aldosterone blockade in myocardial infarction. Heart. 2018 Nov; 104(22): 1843-1849. 27. Blachutzik F, Achenbach S, Tröbs M, Marwan M, Weissner M, Nef H, Schlundt C. Effect of non-compliant balloon postdilatation on magnesium-based bioresorbable vascular scaffolds. Catheter Cardiovasc Interv. 2018 Sep 9: In press. 28. Blumenstein J, Kriechbaum SD, Leick J, Meyer A, Kim WK, Wolter JS, Abu-Samra M, Weipert K, Bayer M, Dörr O, Walther C, Hamm CW, Nef H, Liebetrau C, Möllmann H. Outcome of thrombus aspiration in STEMI patients: a propensity score-adjusted study. J Thromb Thrombolysis. 2018 Dec 23; 45: 240-249.

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29. Boeckel JN, Palapies L, Klotsche J, Zeller T, von Jeinsen B, Perret MF, Kleinhaus SL, Pieper L, Tzikas S, Leistner D, Bickel C, Stalla GK, Lehnert H, Lindahl B, Wittchen HU, Silber S, Baldus S, Maerz W, Dimmeler S, Blankenberg S, Münzel T, Zeiher AM, Keller T. Adjusted Troponin I for Improved Evaluation of Patients with Chest Pain. Sci Rep. 2018 May 24; 8(1): 8087. 30. Boeckel JN, Perret MF, Glaser SF, Seeger T, Heumuller AW, Chen W, John D, Kokot KE, Katus HA, Haas J, Lackner MK, Kayvanpour E, Grabe N, Dieterich C, von Haehling S, Ebner N, Hunecke S, Leuschner F, Fichtlscherer S, Meder B, Zeiher AM, Dimmeler S, Keller T. Identification and regulation of the long non-coding RNA Heat2 in heart failure. J Mol Cell Cardiol. 2018 Nov 13: In press. 31. Boeder NF, Dörr O, Bauer T, Elsässer A, Möllmann H, Achenbach S, Hamm CW, Nef HM. Effect of plaque composition, morphology, and burden on DESolve novolimus-eluting bioresorbable vascular scaffold expansion and eccentricity — An optical coherence tomography analysis. Cardiovascular Revascularization Medicine. 2018 2018/08/02/: In press. 32. Bohula EA, Scirica BM, Inzucchi SE, McGuire DK, Keech AC, Smith SR, Kanevsky E, Murphy SA, Leiter LA, Dwyer JP, Corbalan R, Hamm C, Kaplan L, Nicolau JC, Ophuis TO, Ray KK, Ruda M, Spinar J, Patel T, Miao W, Perdomo C, Francis B, Dhadda S, Bonaca MP, Ruff CT, Sabatine MS, Wiviott SD. Effect of lorcaserin on prevention and remission of type 2 diabetes in overweight and obese patients (CAMELLIA-TIMI 61): a randomised, placebo-controlled trial. Lancet. 2018 Nov 24; 392(10161): 2269-2279. 33. Bonaca MP, Wiviott SD, Morrow DA, Steg PG, Hamm C, Bhatt DL, Storey RF, Cohen M, Kuder J, Im K, Magnani G, Budaj A, Nicolau JC, Parkhomenko A, Lopez-Sendon J, Dellborg M, Diaz R, Van de Werf F, Corbalan R, Goudev A, Jensen EC, Johanson P, Braunwald E, Sabatine MS. Reduction in Subtypes and Sizes of Myocardial Infarction With Ticagrelor in PEGASUS-TIMI 54. J Am Heart Assoc. 2018 Nov 20; 7(22): e009260. 34. Borisenko O, Müller-Ehmsen J, Lindenfeld J, Rafflenbeul E, Hamm C. An early analysis of cost-utility of baroreflex activation therapy in advanced chronic heart failure in Germany. BMC Cardiovasc Disord. 2018 Aug 9; 18(1): 163. 35. Canivell S, Müller O, Gencer B, Heg D, Klingenberg R, Raber L, Carballo D, Matter C, Lüscher T, Windecker S, Mach F, Rodondi N, Nanchen D. Prognosis of cardiovascular and non-cardiovascular multimorbidity after acute coronary syndrome. PLoS One. 2018 13(4): e0195174. 36. Capranzano P, Capodanno D, Brugaletta S, Latib A, Mehilli J, Nef H, Gori T, Lesiak M, Geraci S, Pyxaras S, Mattesini A, Münzel T, Araszkiewicz A, Caramanno G, Naber C, Di Mario C, Sabate M, Colombo A, Wiebe J, Tamburino C. Clinical outcomes of patients with diabetes mellitus treated with Absorb bioresorbable vascular scaffolds: a subanalysis of the European Multicentre GHOST- EU Registry. Catheter Cardiovasc Interv. 2018 Oct 25; 91(3): 444-453. 37. Collet JP, Kerneis M, Lattuca B, Yan Y, Cayla G, Silvain J, Lapostolle F, Ecollan P, Diallo A, Vicaut E, Hamm CW, Van 't Hof AW, Montalescot G. Impact of age on the effect of pre-hospital P2Y12 receptor inhibition in primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: the ATLANTIC-Elderly analysis. EuroIntervention. 2018 Sep 20; 14(7): 789-797. 38. D'Ascenzo F, Celentani D, Brustio A, Grosso A, Raposeiras-Roubin S, Abu-Assi E, Henriques JPS, Saucedo J, Gonzalez-Juanatey JR, Wilton SB, Kikkert WJ, Nunez-Gil I, Ariza-Sole A, Song X, Alexopoulos D, Liebetrau C, Kawaji T, Huczek Z, Nie SP, Fujii T, Correia L, Kawashiri MA, Garcia-Acuna JM, Southern D, Alfonso E, Terol B, Garay A, Zhang D, Chen Y, Xanthopoulou I, Osman N, Mollmann H, Shiomi H, Kowara M, Filipiak K, Wang X, Yan Y, Fan JY, Ikari Y, Nakahayshi T, Sakata K, Yamagishi M, Kalpak O, Kedev S, Moretti C, D'Amico M, Gaita F. Association of Beta- Blockers with Survival on Patients Presenting with ACS Treated with PCI: A Propensity Score Analysis from the BleeMACS Registry. Am J Cardiovasc Drugs. 2018 Aug; 18(4): 299-309. 39. Desch S, Freund A, Graf T, Fichtlscherer S, Haake H, Preusch M, Hammer F, Akin I, Christ M, Liebetrau C, Skurk C, Steiner S, Voigt I, Schmitz R, Mudra H, Ledwoch J, Menck N, Horstkotte J, Pels K, Lahmann AL, Otto S, Lenk K, Ohlow MA, Hassager C, Nordbeck P, Zeymer U, Jobs A, de Waha-Thiele S, Olbrich D, Konig I, Klinge K, Thiele H. Immediate unselected coronary angiography versus delayed triage in survivors of out-of-hospital cardiac arrest without ST-segment elevation: Design and rationale of the TOMAHAWK trial. Am Heart J. 2018 Dec 11; 209: 20-28. 40. Diener HC, Grau AJ, Baldus S, Ghanem A, Groschel K, Liebetrau C, Massberg S, Möllmann H, Nef H, Sander D, Weimar C, Wöhrle J, Mattle H. [Cryptogenic stroke and patent foramen ovale : S2e guide lines]. Nervenarzt. 2018 Sep 25; 89(10): 1143-1153. 41. Diouf K, Elsner L, Rohr M, Wolter JS, Dorr O, Hamm CW, Liebetrau C, Keller T. Anti-citrullinated protein antibodies are not associated with extent of disease or prognosis in patients with coronary artery disease. Clin Chem Lab Med. 2018 Nov 9: In press.

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42. Dörr O, Walther C, Liebetrau C, Keller T, Ortlieb RM, Boeder N, Bauer P, Möllmann H, Gaede L, Troidl C, Voss S, Bauer T, Hamm CW, Nef H. Evaluation of cystatin C and NGAL as predictors of mortality in patients undergoing percutaneous mitral valve repair (MitraClip). Clin Cardiol. 2018 Oct 3; 41(11): 1174-1179.

43. Dörr O, Walther C, Liebetrau C, Keller T, Sommer T, Boeder N, Bayer M, Bauer P, Möllmann H, Gaede L, Troidl C, Voss S, Bauer T, Hamm CW, Nef H. Galectin-3 and ST2 as predictors of therapeutic suc-cess in high-risk patients undergoing percutaneous mitral valve repair (MitraClip). Clin Cardiol. 2018 Sep; 41(9): 1164-1169.

44. Dörr O, Walther C, Liebetrau C, Keller T, Tabert H, Boeder N, Bayer M, Bauer P, Mollmann H, Gaede L, Troidl C, Voss S, Bauer T, Hamm CW, Nef H. Specific biomarkers of myocardial inflammation and remodeling processes as predictors of mortality in high-risk patients undergoing percutaneous mi-tral valve repair (MitraClip). Clin Cardiol. 2018 Apr 17; 41(4): 481-487.

45. Eckardt L, Frommeyer G, Sommer P, Steven D, Deneke T, Estner HL, Kriatselis C, Kuniss M, Busch S, Tilz RR, Bonnemeier H, von Bary C, Voss F, Meyer C, Thomas D, Neuberger HR. Updated Survey on Interventional Electrophysiology: 5-Year Follow-Up of Infrastructure, Procedures, and Training Posi-tions in Germany. JACC Clin Electrophysiol. 2018 Jun; 4(6): 820-827

46. Eisen A, Harrington RA, Stone GW, Steg PG, Gibson CM, Hamm CW, Price MJ, Prats J, Deliargyris EN, Mahaffey KW, White HD, Bhatt DL. Cangrelor compared with clopidogrel in patients with prior myo-cardial infarction - Insights from the CHAMPION trials. Int J Cardiol. 2018 Oct 05; 250: 49-55.

47. Ellis SG, Gori T, Serruys PW, Nef H, Steffenino G, Brugaletta S, Münzel T, Feliz C, Schmidt G, Sabate M, Onuma Y, van Geuns RJ, Gao RL, Menichelli M, Kereiakes DJ, Stone GW, Testa L, Kimura T, Abi-zaid A. Clinical, Angiographic, and Procedural Correlates of Very Late Absorb Scaffold Thrombosis: Multistudy Registry Results. JACC Cardiovasc Interv. 2018 Apr 9; 11(7): 638-644.

48. Ensminger S, Fujita B, Bauer T, Möllmann H, Beckmann A, Bekeredjian R, Bleiziffer S, Landwehr Hamm CW, Mohr FW, Katus HA, Harringer W, Walther T, Frerker C. Rapid Deployment Versus

Conventional Bioprosthetic Valve Replacement for Aortic Stenosis. J Am Coll Cardiol. 2018 Apr 3; 71(13): 1417-1428. 49. Fabris E, Ottervanger JP, Hermanides RS, Ten Berg JM, Sinagra G, Koopmans PC, Giannitsis E, Hamm

C, van 't Hof AWJ. Effect of early tirofiban administration on N-terminal pro-B-type natriuretic peptide level in patients treated with primary percutaneous coronary intervention. Catheter Car-diovasc Interv. 2018 Dec 26: In press.

50. Fabris E, Van't Hof A, Hamm CW, Lapostolle F, Lassen JF, Goodman SG, Ten Berg JM, Bolognese L, Cequier A, Chettibi M, Hammett CJ, Huber K, Janzon M, Merkely B, Storey RF, Zeymer U, Cantor WJ,Kerneis M, Diallo A, Vicaut E, Montalescot G. Pre-hospital administration of ticagrelor in diabetic patients with ST-elevation myocardial infarction undergoing primary angioplasty: A sub-analysis of the ATLANTIC trial. Catheter Cardiovasc Interv. 2018 Oct 9: In press

51. Ferreira JP, Barros A, Pitt B, Montalescot G, de Sa EL, Hamm CW, Flather M, Verheugt F, Shi H, Leite-Moreira A, Vincent J, Rossignol P, Zannad F. Collagen biomarker bioprofiles predicting the antifibrotic response to eplerenone in myocardial infarction: findings from the REMINDER trial. Clin Res Cardiol. 2018 Dec; 107(12): 1192-1195.

52. Ferreira JP, Duarte K, Montalescot G, Pitt B, de Sa EL, Hamm CW, Flather M, Verheugt F, Shi H, Tur-gonyi E, Orri M, Rossignol P, Vincent J, Zannad F. Effect of eplerenone on extracellular cardiac matrix biomarkers in patients with acute ST-elevation myocardial infarction without heart failure: insights from the randomized double-blind REMINDER Study. Clin Res Cardiol. 2018 Jan; 107(1): 49-59.

53. Fujita B, Ensminger S, Bauer T, Möllmann H, Beckmann A, Bekeredjian R, Bleiziffer S, Schäfer E, Hamm CW, Mohr FW, Katus HA, Harringer W, Walther T, Frerker C. Trends in practice and outcomes from 2011 to 2015 for surgical aortic valve replacement: an update from the German Aortic Valve Registry on 42 776 patients. Eur J Cardiothorac Surg. 2018 Nov 27; 53: 552-559.

54. Gaede L, Blumenstein J, Liebetrau C, Dörr O, Kim WK, Nef H, Husser O, Elsasser A, Hamm CW, Möll-mann H. Outcome after transvascular transcatheter aortic valve implantation in 2016. Eur Heart J. 2018 Dec 8; 39: 667-675.

55. Gaede L, Kim WK, Liebetrau C, Dörr O, Sperzel J, Blumenstein J, Berkowitsch A, Walther T, Hamm C, Elsässer A, Nef H, Möllmann H. Pacemaker implantation after TAVI: predictors of AV block persis-tence. Clin Res Cardiol. 2018 Sep 29; 107(1): 60-69.

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56. Garay A, Ariza-Sole A, Formiga F, Raposeiras-Roubin S, Abu-Assi E, Sanchez-Salado JC, Lorente V, Alegre O, Henriques JPS, D'Ascenzo F, Saucedo J, Gonzalez-Juanatey JR, Wilton SB, Kikkert WJ, Nunez-Gil I, Song X, Alexopoulos D, Liebetrau C, Kawaji T, Moretti C, Huczek Z, Nie SP, Fujii T, Correia L, Kawashiri MA, Garcia-Acuna JM, Southern D, Alfonso E, Terol B, Zhang D, Chen Y, Xanthopoulou I, Osman N, Möllmann H, Shiomi H, Giordana F, Gaita F, Kowara M, Filipiak K, Wang X, Yan Y, Fan JY, Ikari Y, Nakahashi T, Sakata K, Yamagishi M, Kalpak O, Kedev S, Cequier A. Prediction of Post-Discharge Bleeding in Elderly Patients with Acute Coronary Syndromes: Insights from the BleeMACS Registry. Thromb Haemost. 2018 May; 118(5): 929-938. 57. Gaul DS, Weber J, Van Tits LJ, Sluka S, Pasterk L, Reiner MF, Calatayud N, Lohmann C, Klingenberg R, Pahla J, Vdovenko D, Tanner FC, Camici GG, Eriksson U, Auwerx J, Mach F, Windecker S, Rodondi N, TF LUS, Winnik S, Matter CM. Loss of Sirt3 accelerates arterial thrombosis by increasing formation of neutrophil extracellular traps and plasma tissue factor activity. Cardiovasc Res. 2018 Feb 10: In press. 58. Gemein C, Roos M, Wolf A, Hermann N, Kelava A, Chasan R, Weipert K, Helmig I, Bogossian H, Hamm CW, Neumann T, Schmitt J, Erkapic D. Tilt testing and what you should know about it - Experience with 835 consecutive patients with syncope of unknown origin. Int J Cardiol. 2018 Jan 31; 258: 90-96. 59. Gencer B, Rigamonti F, Nanchen D, Klingenberg R, Raber L, Moutzouri E, Auer R, Carballo D, Heg D, Windecker S, Lüscher TF, Matter CM, Rodondi N, Mach F, Roffi M. Prognostic values of fasting hyperglycaemia in non-diabetic patients with acute coronary syndrome: A prospective cohort study. Eur Heart J Acute Cardiovasc Care. 2018 Jun 1: In press. 60. Ghadri JR, Wittstein IS, Prasad A, Sharkey S, Dote K, Akashi YJ, Cammann VL, Crea F, Galiuto L, Desmet W, Yoshida T, Manfredini R, Eitel I, Kosuge M, Nef HM, Deshmukh A, Lerman A, Bossone E, Citro R, Ueyama T, Corrado D, Kurisu S, Ruschitzka F, Winchester D, Lyon AR, Omerovic E, Bax JJ, Meimoun P, Tarantini G, Rihal C, S YH, Migliore F, Horowitz JD, Shimokawa H, Lüscher TF, Templin C. International Expert Consensus Document on Takotsubo Syndrome (Part II): Diagnostic Workup, Outcome, and Management. Eur Heart J. 2018 Jun 7; 39(22): 2047-2062. 61. Ghadri JR, Wittstein IS, Prasad A, Sharkey S, Dote K, Akashi YJ, Cammann VL, Crea F, Galiuto L, Desmet W, Yoshida T, Manfredini R, Eitel I, Kosuge M, Nef HM, Deshmukh A, Lerman A, Bossone E, Citro R, Ueyama T, Corrado D, Kurisu S, Ruschitzka F, Winchester D, Lyon AR, Omerovic E, Bax JJ, Meimoun P, Tarantini G, Rihal C, S YH, Migliore F, Horowitz JD, Shimokawa H, Lüscher TF, Templin C. International Expert Consensus Document on Takotsubo Syndrome (Part I): Clinical Characteristics, Diagnostic Criteria, and Pathophysiology. Eur Heart J. 2018 Jun 7; 39(22): 2032-2046. 62. Grodecki K, Huczek Z, Scislo P, Kowara M, Raposeiras-Roubin S, D'Ascenzo F, Abu-Assi E, Henriques JPS, Saucedo J, Gonzalez-Juanatey JR, Wilton SB, Kikkert WJ, Nunez-Gil I, Ariza-Sole A, Song XT, Alexopoulos D, Liebetrau C, Kawaji T, Moretti C, Nie SP, Fujii T, Correia L, Kawashiri MA, Garcia-Acuna JM, Southern D, Alfonso E, Terol B, Garay A, Zhang D, Chen Y, Xanthopoulou I, Osman N, Möllmann H, Shiomi H, Giordana F, Scarano S, Gaita F, Wang X, Yan Y, Fan JY, Ikari Y, Nakahashi T, Sakata K, Yamagishi M, Kalpak O, Kedev S, Opolski G, Filipiak KJ. Gender-related differences in post-discharge bleeding among patients with acute coronary syndrome on dual antiplatelet therapy: A BleeMACS sub-study. Thromb Res. 2018 Aug; 168: 156-163. 63. Groves EM, Bhatt DL, Steg PG, Deliargyris EN, Stone GW, Gibson CM, Hamm CW, Mahaffey KW, White HD, Angiolillo D, Prats J, Harrington RA, Price MJ. Incidence, Predictors, and Outcomes of Acquired Thrombocytopenia After Percutaneous Coronary Intervention: A Pooled, Patient-Level Analysis of the CHAMPION Trials (Cangrelor Versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition). Circ Cardiovasc Interv. 2018 Apr; 11(4): e005635. 64. Guth S, Wiedenroth CB, Rieth A, Richter MJ, Gruenig E, Ghofrani HA, Arlt M, Liebetrau C, Prufer D, Rolf A, Hamm CW, Mayer E. Exercise right heart catheterization before and after pulmonary endarterectomy in patients with chronic thromboembolic disease. Eur Respir J. 2018 Aug 23; 52(3): 1800458. 65. Hain A, Hamm C, Sperzel J. [Symptomatic bradycardia with exitblock in a leadless pacemaker]. Herzschrittmacherther Elektrophysiol. 2018 Dec; 29(4): 401-405. 66. Hamm C, Hamm CW. [MINOCA-myocardial infarction with non-obstructive coronary arteries]. Herz. 2018 Dec; 43(8): 759-770. 67. Hamm CW, Mohr F, Heusch G. Lessons Learned From the German Aortic Valve Registry. J Am Coll Cardiol. 2018 Aug 7; 72(6): 689-692. 68. Harbaoui B, Nanchen D, Lantelme P, Gencer B, Heg D, Klingenberg R, Raber L, Carballo D, Matter CM, Windecker S, Mach F, Rodondi N, Eeckhout E, Monney P, Antiochos P, Schwitter J, Pascale P, Fournier S, Courand PY, Lüscher TF, Müller O. Prognostic value of pulse pressure after an acute coronary syndrome. Atherosclerosis. 2018 Oct; 277: 219-226.

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69. Hinohara TT, Roe MT, White HD, Fox KAA, Bhatt DL, Hamm C, Gurbel PA, Aylward PE, Wiviott SD, Huber K, Neely ML, Ohman EM. Outcomes of Patients Receiving Downstream Revascularization After Initial Medical Management for Non-ST-Segment Elevation Acute Coronary Syndromes (From the TRILOGY ACS Trial). Am J Cardiol. 2018 Oct 15; 122(8): 1322-1329.

70. Hinrichs S, Scherschel K, Kruger S, Neumann JT, Schwarzl M, Yan I, Warnke S, Ojeda FM, Zeller T, Karakas M, Keller T, Meyer C, Blankenberg S, Westermann D, Lindner D. Precursor proadrenome-dullin influences cardiomyocyte survival and local inflammation related to myocardial infarction. Proc Natl Acad Sci U S A. 2018 Sep 11; 115(37): E8727-e8736.

71. Husser O, Fujita B, Hengstenberg C, Frerker C, Beckmann A, Möllmann H, Walther T, Bekeredjian R, Böhm M, Pellegrini C, Bleiziffer S, Lange R, Mohr F, Hamm CW, Bauer T, Ensminger S. Conscious Se-dation Versus General Anesthesia in Transcatheter Aortic Valve Replacement: The German Aortic Valve Registry. JACC Cardiovasc Interv. 2018 Mar 26; 11(6): 567-578.

72. Iannaccone M, D'Ascenzo F, Vadala P, Wilton SB, Noussan P, Colombo F, Raposeiras Roubin S, Abu Assi E, Gonzalez-Juanatey JR, Simao Henriques JP, Saucedo J, Kikkert WJ, Nunez-Gil I, Ariza-Sole A, Song XT, Alexopoulos D, Liebetrau C, Kawaji T, Moretti C, Garbo R, Huczek Z, Nie SP, Fujii T, Correia LC, Kawashiri MA, Garcia Acuna JM, Southern D, Alfonso E, Terol B, Garay A, Zhang D, Chen Y, Xan-thopoulou I, Osman N, Möllmann H, Shiomi H, Giordana F, Kowara M, Filipiak K, Wang X, Yan Y, Fan JY, Ikari Y, Nakahashi T, Sakata K, Gaita F, Yamagishi M, Kalpak O, Kedev S. Prevalence and outcome of patients with cancer and acute coronary syndrome undergoing percutaneous coronary interven-tion: a BleeMACS substudy. Eur Heart J Acute Cardiovasc Care. 2018 Oct; 7(7): 631-638.

73. Ijsselmuiden AJJ, Zwaan EM, Oemrawsingh RM, Bom MJ, Dankers F, de Boer MJ, Camaro C, van Ge-uns RJM, Daemen J, van der Heijden DJ, Jukema JW, Kraaijeveld AO, Meuwissen M, Scholzel BE, Pundziute G, van der Harst P, van Ramshorst J, Dirksen MT, Zivelonghi C, Agostoni P, van der Heyden JAS, Wykrzykowska JJ, Scholte MJ, Nef HM, Kofflard MJM, van Royen N, Alings M, Kedhi E. Appropri-ate use criteria for optical coherence tomography guidance in percutaneous coronary interventions Recommendations of the working group of interventional cardiology of the Netherlands Society of Cardiology. Neth Heart J. 2018 Oct; 26(10): 473-483.

74. Jenewein T, Neumann T, Erkapic D, Kuniss M, Verhoff MA, Thiel G, Kauferstein S. Influence of genetic modifiers on sudden cardiac death cases. Int J Legal Med. 2018 Mar; 132(2): 379-385.

75. Juenemann M, Nef H, Möllmann H, Singh P, Troidl C, Schramm P, Kaps M, Gerriets T, Blaes F, Tscher-natsch M. No evidence for humoral autoimmunity against cardiomyocytes, adrenergic or muscarinic receptors in patients with Tako-Tsubo cardiomyopathy. Immunobiology. 2018 Nov 15: In press.

76. Keller T, Hamm CW. High-sensitivity cardiac troponin assays: finally ready for prime time? Nat Rev Cardiol. 2018 Nov 21: In press.

77. Keller T, Wanner C, Krane V, Kraus D, Genser B, Scharnagl H, Marz W, Drechsler C. Prognostic Value of High-Sensitivity Versus Conventional Cardiac Troponin T Assays Among Patients With Type 2 Dia-betes Mellitus Undergoing Maintenance Hemodialysis. Am J Kidney Dis. 2018 Jun; 71(6): 822-830.

78. Kelm M, Kastrati A, Nef H, Richardt G, Zeymer U, Bauersachs J, Kommission Klin K. Comments on the 2017 guidelines of the European Society of Cardiology (ESC) on the management of acute myocar-dial infarction in patients with ST-segment elevation. Kardiologe. 2018 Apr; 12(2): 145-149.

79. Kilic S, Fabris E, Van't Hof AWJ, Hamm CW, Lapostolle F, Lassen JF, Tsatsaris A, Diallo A, Vicaut E, Montalescot G. Thrombus aspiration and prehospital ticagrelor administration in ST-elevation myocardial infarction: Findings from the ATLANTIC trial. Am Heart J. 2018 Feb; 196: 1-8.

80. Kim WK, Gaede L, Husser O, Liebetrau C, Renker M, Rolf A, Fischer-Rasokat U, Möllmann S, Blumen-stein J, Guenther E, Van Linden A, Arsalan M, Doss M, Loders S, Arnold M, Hamm CW, Walther T, Achenbach S, Möllmann H. Computed Tomography for Diagnosis and Classification of Bicuspid Aor-tic Valve Disease in Transcatheter Aortic Valve Replacement. JACC Cardiovasc Imaging. 2018 Oct; 11(10): 1539-1540.

81. Kim WK, Hamm CW. Early discharge and late onset conduction disturbances - A conflict of interest? Int J Cardiol. 2018 Sep 11; 273: 88-89.

82. Kim WK, Hamm CW. Transcatheter aortic valve implantation in Germany. Clin Res Cardiol. 2018 Aug; 107(Suppl 2): 81-87.

83. Kim WK, Hengstenberg C, Hilker M, Kerber S, Schafer U, Rudolph T, Linke A, Franz N, Kuntze T, Nef H, Kappert U, Zembala MO, Toggweiler S, Walther T, Möllmann H. The SAVI-TF Registry: 1-Year Out-comes of the European Post-Market Registry Using the ACURATE neo Transcatheter Heart Valve Under Real-World Conditions in 1,000 Patients. JACC Cardiovasc Interv. 2018 Jul 23; 11(14): 1368-1374.

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84. Kim WK, Möllmann H, Liebetrau C, Renker M, Rolf A, Simon P, Van Linden A, Arsalan M, Doss M, Hamm CW, Walther T. The ACURATE Neo Transcatheter Heart Valve: A Comprehensive Analysis of Predictors of Procedural Outcome. JACC Cardiovasc Interv. 2018 May 21; 11(17): 1721-1729. 85. Kim WK, Renker M, Rolf A, Liebetrau C, Van Linden A, Arsalan M, Doss M, Rieck J, Opolski MP, Moellmann H, Walther T, Hamm CW. Accuracy of device landing zone calcium volume measurement with contrast-enhanced multidetector computed tomography. Int J Cardiol. 2018 Jul 15; 263: 171-176. 86. Klingenberg R, Aghlmandi S, Raber L, Gencer B, Nanchen D, Heg D, Carballo S, Rodondi N, Mach F, Windecker S, Juni P, von Eckardstein A, Matter CM, Lüscher TF. Improved risk stratification of patients with acute coronary syndromes using a combination of hsTnT, NT-proBNP and hsCRP with the GRACE score. Eur Heart J Acute Cardiovasc Care. 2018 Mar; 7(2): 129-138. 87. Klingenberg R, Lüscher TF. CANTOS: a seductive song with several verses. Eur Heart J. 2018 Oct 7: 39(38): 3508-3510. 88. Koehne J, Doss M, Kim WK, Walther T. Pusher preventing maximum expansion of transfemoral transcatheter valves. Interact Cardiovasc Thorac Surg. 2018 Feb 1; 26(2): 355-356. 89. Koskinas KC, Zanchin T, Klingenberg R, Gencer B, Temperli F, Baumbach A, Roffi M, Moschovitis A, Müller O, Tuller D, Stortecky S, Mach F, Lüscher TF, Matter CM, Pilgrim T, Heg D, Windecker S, Raber L. Incidence, Predictors, and Clinical Impact of Early Prasugrel Cessation in Patients With ST-Elevation Myocardial Infarction. J Am Heart Assoc. 2018 Apr 13; 7(8): e008085. 90. Kraus D, von Jeinsen B, Tzikas S, Palapies L, Zeller T, Bickel C, Fette G, Lackner KJ, Drechsler C, Neumann JT, Baldus S, Blankenberg S, Munzel T, Wanner C, Zeiher AM, Keller T. Cardiac Troponins for the Diagnosis of Acute Myocardial Infarction in Chronic Kidney Disease. J Am Heart Assoc. 2018 Oct 2; 7(19): e008032. 91. Kriechbaum SD, Wiedenroth CB, Keller T, Wolter JS, Ajnwojner R, Peters K, Haas MA, Roller FC, Breithecker A, Rieth AJ, Guth S, Rolf A, Bandorski D, Hamm CW, Mayer E, Liebetrau C. Dynamics of high-sensitivity cardiac troponin T during therapy with balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension. PLoS One. 2018 13(9): e0204683. 92. Kriechbaum SD, Wiedenroth CB, Wolter JS, Hutz R, Haas M, Breithecker A, Roller FC, Keller T, Guth S, Rolf A, Hamm CW, Mayer E, Liebetrau C. N-terminal pro-B-type natriuretic peptide for monitoring after balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension. J Heart Lung Transplant. 2018 Dec 8; 37(5): 639-646. 93. Lankeit M, Krieg V, Hobohm L, Kolmel S, Liebetrau C, Konstantinides S, Hamm CW, Mayer E, Wiedenroth CB, Guth S. Pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension. J Heart Lung Transplant. 2018 Jul 01; 37(2): 250-258. 94. Lapostolle F, Van't Hof AW, Hamm CW, Stibbe O, Ecollan P, Collet JP, Silvain J, Lassen JF, Heutz W, Bolognese L, Cantor WJ, Cequier A, Chettibi M, Goodman SG, Hammett CJ, Huber K, Janzon M, Merkely B, Storey RF, Ten Berg J, Zeymer U, Licour M, Tsatsaris A, Montalescot G. Morphine and Ticagrelor Interaction in Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction: ATLANTIC-Morphine. Am J Cardiovasc Drugs. 2018 Oct 23: In press. 95. Lauder L, Ewen S, Tzafriri AR, Edelman ER, Luscher TF, Blankenstijn PJ, Dörr O, Schlaich M, Sharif F, Voskuil M, Zeller T, Ukena C, Scheller B, Böhm M, Mahfoud F. Renal artery anatomy assessed by quantitative analysis of selective renal artery in 1000 patients with hypertension. EuroIntervention. 2018 May 20; 14(1): 121-128. 96. Leonardi S, Lopes RD, Steg PG, Abnousi F, Menozzi A, Prats J, Mangum S, Wilson M, Todd M, Stone GW, Gibson CM, Hamm CW, Price MJ, White HD, Harrington RA, Bhatt DL, Mahaffey KW. Implications of different criteria for percutaneous coronary intervention-related myocardial infarction on study results of three large phase III clinical trials: The CHAMPION experience. Eur Heart J Acute Cardio vasc Care. 2018 Mar; 7(2): 158-165. 97. Leschik J, Bauer T. [Acute coronary syndrome]. MMW Fortschr Med. 2018 Aug; 160(14): 52-61. 98. Liebetrau C, Elsasser A, Nef H, Möllmann H. Management of acute coronary syndrome. Kardiologe. 2018 Sep; 12(5): 371-390. 99. Liebetrau C, Gaede L, Kim WK, Arsalan M, Blumenstein JM, Fischer-Rasokat U, Wolter JS, Kriechbaum S, Huber MT, van Linden A, Berkowitsch A, Dörr O, Nef H, Hamm CW, Walther T, Möllmann H. Early changes in N-terminal pro-B-type natriuretic peptide levels after transcatheter aortic valve replacement and its impact on long-term mortality. Int J Cardiol. 2018 Aug 15; 265: 40-46. 100. Liebetrau C, Hamm CW. Persistierendes Foramen ovale – Intervention oder Arzneitherapie. Internist. 2018 Sept; 59(9): 981-992.

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101. Lipps C, Klein F, Wahlicht T, Seiffert V, Butueva M, Zauers J, Truschel T, Luckner M, Koster M, MacLeod R, Pezoldt J, Huhn J, Yuan Q, Muller PP, Kempf H, Zweigerdt R, Dittrich-Breiholz O, Pufe T, Beckmann R, Drescher W, Riancho J, Sanudo C, Korff T, Opalka B, Rebmann V, Gothert JR, Alves PM, Ott M, Schucht R, Hauser H, Wirth D, May T. Expansion of functional personalized cells with specific transgene combinations. Nat Commun. 2018 Mar 8; 9(1): 994 102. Mitrovic V, Forssmann WG, Schnitker J, Felix SB. Randomized double-blind clinical studies of ularitide and other vasoactive substances in acute decompensated heart failure: a systematic review and meta-analysis. ESC Heart Fail. 2018 Dec; 5(6): 1023-1034. 103. Möllmann H, Hamm CW, Gaede L. European Heart Journal, discussion forum. Eur Heart J. 2018 Nov 13; 2018: 1. 104. Möllmann H, Hengstenberg C, Hilker M, Kerber S, Schafer U, Rudolph T, Linke A, Franz N, Kuntze T, Nef H, Kappert U, Walther T, Zembala MO, Toggweiler S, Kim WK. Real-world experience using the ACURATE neo prosthesis: 30-day outcomes of 1000 patients enrolled in the SAVI-TF registry. Euro Intervention. 2018 Feb 2; 13(15): e1764-e1770. 105. Most AK, Bauer T, Nef H, Hamm C, Bauer P. Malignant anomalous origin of circumflex artery in an elite athlete. Clin Res Cardiol. 2018 Dec 17: In press. 106. Nef H, Wiebe J, Boeder N, Dörr O, Bauer T, Hauptmann KE, Latib A, Colombo A, Fischer D, Rudolph T, Foin N, Richardt G, Hamm C. A multicenter post-marketing evaluation of the Elixir DESolve((R)) Novolimus-eluting bioresorbable coronary scaffold system: First results from the DESolve PMCF study. Catheter Cardiovasc Interv. 2018 Nov 15; 92(6): 1021-1027. 107. Nef HM, Abdel-Wahab M, Achenbach S, Joner M, Levenson B, Mehilli J, Möllmann H, Thiele H, Zahn R, Zeus T, Elsässer A. Drug-eluting coronary stents/coronary scaffolds and drug-coated balloon catheters. Position paper of the interventional cardiology working group (AGIK) of the German Society of Cardiology Cardiac and Circulatory Research. Kardiologe. 2018 Feb; 12(1): 26-52. 108. Neumann JT, Sörensen NA, Rübsamen N, Ojeda F, Schafer S, Keller T, Blankenberg S, Clemmensen P, Westermann D. Right bundle branch block in patients with suspected myocardial infarction. Eur Heart J Acute Cardiovasc Care. 2018 Oct 26: In press. 109. Obeid S, Frangieh AH, Raber L, Yousif N, Gilhofer T, Yamaji K, Jaguszewski M, Aghlmandi S, Adams J, Bockhorn Y, Templin C, Stähli BE, Juni P, Rodondi N, Mach F, Roffi M, Windecker S, Maier W, Nietlispach F, Matter CM, Klingenberg R, Lüscher TF. Prognostic Value of SYNTAX Score II in Patients with Acute Coronary Syndromes Referred for Invasive Management: A Subanalysis from the SPUM and COMFORTABLE AMI Cohorts. Cardiol Res Pract. 2018 2018: 9762176. 110. Olivier CB, Sundaram V, Bhatt DL, Leonardi S, Lopes RD, Ding VY, Yang L, Stone GW, Steg PG, Gibson CM, Hamm CW, Price MJ, White HD, Desai M, Lynch DR, Jr., Harrington RA, Mahaffey KW. Definitions of peri-procedural myocardial infarction and the association with one-year mortality: Insights from CHAMPION trials. Int J Cardiol. 2018 Jun 8; 270: 96-101. 111. Parahuleva MS, Lipps C, Parviz B, Holschermann H, Schieffer B, Schulz R, Euler G. MicroRNA expression profile of human advanced coronary atherosclerotic plaques. Sci Rep. 2018 May 18; 8(1): 7823. 112. Pellegrini C, Husser O, Kim WK, Holzamer A, Walther T, Rheude T, Mayr NP, Trenkwalder T, Joner M, Michel J, Chaustre F, Kastrati A, Schunkert H, Burgdorf C, Hilker M, Möllmann H, Hengstenberg C. Predictors of Need for Permanent Pacemaker Implantation and Conduction Abnormalities With a Novel Self-expanding Transcatheter Heart Valve. Rev Esp Cardiol (Engl Ed). 2018: In press. 113. Pellegrini C, Kim WK, Holzamer A, Walther T, Mayr NP, Michel J, Rheude T, Nunez J, Kasel AM, Trenkwalder T, Kaess BM, Joner M, Kastrati A, Schunkert H, Hilker M, Möllmann H, Hengstenberg C, Husser O. Multicenter Evaluation of Prosthesis Oversizing of the SAPIEN 3 Transcatheter Heart Valve. Impact on Device Failure and New Pacemaker Implantations. Rev Esp Cardiol (Engl Ed). 2018 Jul 14: In press. 114. Petrie CJ, Ponikowski P, Metra M, Mitrovic V, Ruda M, Fernandez A, Vishnevsky A, Cotter G, Milo O, Laessing U, Zhang Y, Dahlke M, Zymlinski R, Voors AA. Proportional pulse pressure relates to cardiac index in stabilized acute heart failure patients. Clin Exp Hypertens. 2018 40(7): 637-643. 115. Pibarot P, Simonato M, Barbanti M, Linke A, Kornowski R, Rudolph T, Spence M, Moat N, Aldea G, Mennuni M, Iadanza A, Amrane H, Gaia D, Kim WK, Napodano M, Baumbach H, Finkelstein A, Kobayashi J, Brecker S, Don C, Cerillo A, Unbehaun A, Attias D, Nejjari M, Jones N, Fiorina C, Tchetche D, Philippart R, Spargias K, Hernandez JM, Latib A, Dvir D. Impact of Pre-Existing Prosthesis-Patient Mismatch on Survival Following Aortic Valve-in-Valve Procedures. JACC Cardiovasc Interv. 2018 Jan 22; 11(2): 133-141. 116. Puntmann VO, Carr-White G, Jabbour A, Yu CY, Gebker R, Kelle S, Rolf A, Zitzmann S, Peker E, D'Angelo T, Pathan F, Elen, Valbuena S, Hinojar R, Arendt C, Narula J, Herrmann E, Zeiher AM, Nagel E. Native T1 and ECV of Noninfarcted Myocardium and Outcome in Patients With Coronary Artery Disease. J Am Coll Cardiol. 2018 Feb 20; 71(7): 766-778.

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117. Raposeiras-Roubin S, Faxen J, Iniguez-Romo A, Henriques JPS, D'Ascenzo F, Saucedo J, Szummer K, Jernberg T, James SK, Juanatey JRG, Wilton SB, Kikkert WJ, Nunez-Gil I, Ariza-Sole A, Song X, Alexopoulos D, Liebetrau C, Kawaji T, Moretti C, Huczek Z, Nie SP, Fujii T, Correia L, Kawashiri MA, Caneiro-Queija B, Cobas-Paz R, Acuna JMG, Southern D, Alfonso E, Terol B, Garay A, Zhang D, Chen Y, Xanthopoulou I, Osman N, Möllmann H, Shiomi H, Giordana F, Gaita F, Kowara M, Filipiak K, Wang X, Yan Y, Fan JY, Ikari Y, Nakahayshi T, Sakata K, Yamagishi M, Kalpak O, Kedev S, Rivera- Asenjo D, Abu-Assi E. Development and external validation of a post-discharge bleeding risk score in patients with acute coronary syndrome: The BleeMACS score. Int J Cardiol. 2018 Mar 1; 254: 10-15. 118. Rieth AJ, Richter MJ, Berkowitsch A, Frerix M, Tarner IH, Mitrovic V, Hamm CW. Intravenous sildenafil acutely improves hemodynamic response to exercise in patients with connective tissue disease. PLoS One. 2018 13(9): e0203947. 119. Rinaldi L, Pozdniakova S, Jayarajan V, Troidl C, Abdallah Y, Aslam M, Ladilov Y. Protective role of soluble adenylyl cyclase against reperfusion-induced injury of cardiac cells. BBA Mol Basis Dis. 2018 Jul 22: In press. 120. Rosenkranz S, Lang IM, Blindt R, Bonderman D, Bruch L, Diller GP, Felgendreher R, Gerges C, Hohenforst-Schmidt W, Holt S, Jung C, Kindermann I, Kramer T, Kübler WM, Mitrovic V, Riedel A, Rieth A, Schmeisser A, Wachter R, Weil J, Opitz CF. Pulmonary hypertension associated with left heart disease: Updated Recommendations of the Cologne Consensus Conference 2018. Int J Cardiol. 2018 Dec 1;272S:53-62. 121. Rutsch M, Akin I, Borggrefe M, Renker M, Lossnitzer D, Baumann S. Coronary Computed Tomography-Derived Fractional Flow Reserve Assessment-A Gatekeeper in Intermediate Stenoses. Am J Cardiol. 2018 Dec 25; 121(6): 778-779. 122. Rutsch M, Renker M, Akin I, Borggrefe M, Baumann S. Coronary computed tomography-derived fractional flow reserve assessment - Finally ready for clinical use? J Cardiovasc Comput Tomogr. 2018 Mar 21; 12(3): e5. 123. Schlieper G, Remppis A, Schwenger V, Keller T, Dechend R, Massberg S, Baldus S, Weinreich T, Hetzel G, Floege J, Hoyer J, Mahfoud F, Fliser D. Non-vitamin K antagonist oral anticoagulants (NOAC) in chronic kidney disease. Recommendations of the working group "Heart-Kidneys", of the German Cardiac Society and the German Society of Nephrology. Nephrologe. 2018 Mar; 13(2): 91-98. 124. Sörensen NA, Neumann JT, Ojeda F, Schäfer S, Magnussen C, Keller T, Lackner KJ, Zeller T, Karakas M, Münzel T, Blankenberg S, Westermann D, Schnabel RB. Relations of Sex to Diagnosis and Out comes in Acute Coronary Syndrome. J Am Heart Assoc. 2018 Mar 10; 7(6): e007297. 125. Sperzel J, Defaye P, Delnoy PP, Garcia Guerrero JJ, Knops RE, Tondo C, Deharo JC, Wong T, Neuzil P. Primary safety results from the LEADLESS Observational Study. Europace. 2018 Jan 19; 20: 1491-1497. 126. Sperzel J, Hamm C, Hain A. Nanostim-leadless pacemaker. Herzschrittmacherther Elektrophysiol. 2018 Dec; 29(4): 327-333. 127. Sperzel J, Hamm C, Hain A. Leadless pacing. Herz. 2018 Nov; 43(7): 605-611. 128. Sperzel J, Staudacher I, Goeing O, Stockburger M, Meyer T, Goncalves ASO, Sydow H, Schoenfelder T, Amelung VE. Critical appraisal concerning "Wearable cardioverter defibrillators for the prevention of sudden cardiac arrest: a health technology assessment and patient focus group study". Med Devices (Auckl). 2018 11: 201-204. 129. Stähli BE, Wischnewsky MB, Jakob P, Klingenberg R, Obeid S, Heg D, Raber L, Windecker S, Mach F, Gencer B, Nanchen D, Juni P, Landmesser U, Matter CM, Lüscher TF, Maier W. Gender and age differences in outcomes of patients with acute coronary syndromes referred for coronary angiography. Catheter Cardiovasc Interv. 2018 Oct 5: In press. 130. Stähli BE, Wischnewsky MB, Jakob P, Klingenberg R, Obeid S, Heg D, Raber L, Windecker S, Roffi M, Mach F, Gencer B, Nanchen D, Juni P, Landmesser U, Matter CM, Lüscher TF, Maier W. Predictive value of the age, creatinine, and ejection fraction (ACEF) score in patients with acute coronary syndromes. Int J Cardiol. 2018 Jun 1; 270: 7-13. 131. Stellbrink C, Sperzel J. [New developments in cardiac implantable electronic devices]. Herzschrittmacherther Elektrophysiol. 2018 Dec; 29(4): 325-326. 132. Stone GW, Genereux P, Harrington RA, White HD, Gibson CM, Steg PG, Hamm CW, Mahaffey KW, Price MJ, Prats J, Deliargyris EN, Bhatt DL. Impact of lesion complexity on peri-procedural adverse events and the benefit of potent intravenous platelet adenosine diphosphate receptor inhibition after percutaneous coronary intervention: core laboratory analysis from 10 854 patients from the CHAMPION PHOENIX trial. Eur Heart J. 2018 Dec 7;39(46):4112-4121.

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133. Tello K, Axmann J, Ghofrani HA, Naeije R, Narcin N, Rieth A, Seeger W, Gall H, Richter MJ. Relevance of the TAPSE/PASP ratio in pulmonary arterial hypertension. Int J Cardiol. 2018 Sep 1; 266: 229-235. 134. Tesche C, De Cecco CN, Baumann S, Renker M, McLaurin TW, Duguay TM, Bayer RR, 2nd, Steinberg DH, Grant KL, Canstein C, Schwemmer C, Schoebinger M, Itu LM, Rapaka S, Sharma P, Schoepf UJ. Coronary CT Angiography-derived Fractional Flow Reserve: Machine Learning Algorithm versus Computational Fluid Dynamics Modeling. Radiology. 2018 Jul; 288(1): 64-72. 135. Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, White HD, Mickley H, Crea F, Van de Werf F, Bucciarelli-Ducci C, Katus HA, Pinto FJ, Antman EM, Hamm CW, De Caterina R, Januzzi JL, Jr., Apple FS, Alonso Garcia MA, Underwood SR, Canty JM, Jr., Lyon AR, Devereaux PJ, Zamorano JL, Lindahl B, Weintraub WS, Newby LK, Virmani R, Vranckx P, Cutlip D, Gibbons RJ, Smith SC, Atar D, Luepker RV, Robertson RM, Bonow RO, Steg PG, O'Gara PT, Fox KAA. [Fourth universal definition of myocardial infarction (2018)]. Kardiol Pol. 2018 76(10): 1383-1415. 136. Tjong FVY, Knops RE, Neuzil P, Petru J, Sediva L, Wilde AAM, Sperzel J, Reddy VY. Midterm Safety and Performance of a Leadless Cardiac Pacemaker: 3-Year Follow-up to the LEADLESS Trial (Nanostim Safety and Performance Trial for a Leadless Cardiac Pacemaker System). Circulation. 2018 Feb 6; 137(6): 633-635. 137. Tjong FVY, Beurskens NEG, Neuzil P, Defaye P, Delnoy PP, Ip J, Guerrero JJG, Rashtian M, Banker R, Reddy V, Exner D, Sperzel J, Knops RE. The learning curve associated with the implantation of the Nanostim leadless pacemaker. J Interv Card Electrophysiol. 2018 Nov; 53(2): 239-247. 138. Vaduganathan M, Harrington RA, Stone GW, Steg PG, Gibson CM, Hamm CW, Price MJ, Lopes RD, Leonardi S, Deliargyris EN, Prats J, Mahaffey KW, White HD, Bhatt DL. Short- and long-term mortality following bleeding events in patients undergoing percutaneous coronary intervention: insights from four validated bleeding scales in the CHAMPION trials. EuroIntervention. 2018 Feb 2; 13(15): e1841-e1849. 139. van den Bruck JH, Sultan A, Luker J, Thomas D, Willems S, Weinmann K, Kuniss M, Hochadel M, Senges J, Andresen D, Brachmann J, Kuck KH, Tilz R, Steven D. Remote vs. conventional navigation for catheter ablation of atrial fibrillation: insights from prospective registry data. Clin Res Cardiol. 2018 Aug 29: In press. 140. Vranckx P, Valgimigli M, Juni P, Hamm C, Steg PG, Heg D, van Es GA, McFadden EP, Onuma Y, van Meijeren C, Chichareon P, Benit E, Möllmann H, Janssens L, Ferrario M, Moschovitis A, Zurakowski A, Dominici M, Van Geuns RJ, Huber K, Slagboom T, Serruys PW, Windecker S. Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vs aspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin monotherapy for 12 months after implantation of a drug-eluting stent: a multicentre, open-label, randomised superiority trial. Lancet. 2018 Sep 15; 392 (10151): 940-949. 141. Walther T, Manoharan G, Linke A, Möllmann H, Holzhey D, Worthley SG, Kim WK, Schäfer U. Incidence of new-onset left bundle branch block and predictors of new permanent pacemaker following transcatheter aortic valve replacement with the Portico valve. Eur J Cardiothorac Surg. 2018 Sep 1; 54(3): 467-474. 142. Weipert K, Kuniss M, Neumann T. [Noninvasive mapping for catheter ablation of arrhythmias using the CardioInsight ECG vest]. Herzschrittmacherther Elektrophysiol. 2018 Sep;29(3):293-299. Weipert KF, Andrick J, Chasan R, Gemein C, Most A, Hamm CW, Erkapic D, Schmitt J. Baroreceptor stimulation in a patient with preexisting subcutaneous implantable cardioverter-defibrillator. Pacing Clin Electrophysiol. 2018 May 24; 41: 90-92. 143. Weipert KF, Bogossian H, Conzen P, Frommeyer G, Gemein C, Helmig I, Chasan R, Eckardt L, Seyfarth M, Lemke B, Zarse M, Hamm CW, Schmitt J, Erkapic D. Application of the Bogossian formula for evaluation of the QT interval in pacemaker patients with stimulated left bundle branch block. Clin Res Cardiol. 2018 Nov;107(11):1033-1039. 144. Werner N, Zahn R, Beckmann A, Bauer T, Bleiziffer S, Hamm CW, Berkeredjian R, Berkowitsch A, Mohr FW, Landwehr S, Katus HA, Harringer W, Ensminger S, Frerker C, Möllmann H, Walther T, Schneider S, Lange R. Patients at Intermediate Surgical Risk Undergoing Isolated Interventional or Surgical Aortic Valve Implantation for Severe Symptomatic Aortic Valve Stenosis. Circulation. 2018 Dec 4; 138(23): 2611-2623. 145. Westra J, Andersen BK, Campo G, Matsuo H, Koltowski L, Eftekhari A, Liu T, Di Serafino L, Di Girolamo D, Escaned J, Nef H, Naber C, Barbierato M, Tu S, Neghabat O, Madsen M, Tebaldi M, Tanigaki T, Kochman J, Somi S, Esposito G, Mercone G, Mejia-Renteria H, Ronco F, Botker HE, Wijns W, Christiansen EH, Holm NR. Diagnostic Performance of In-Procedure Angiography-Derived Quantitative Flow Reserve Compared to Pressure-Derived Fractional Flow Reserve: The FAVOR II Europe-Japan Study. J Am Heart Assoc. 2018 Jul 6; 7(14): e009603.

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146. Westra J, Andersen BK, Campo G, Matsuo H, Koltowski L, Eftekhari A, Liu T, Di Serafino L, Di Girolamo D, Escaned J, Nef H, Naber C, Barbierato M, Tu S, Neghabat O, Madsen M, Tebaldi M, Tanigaki T, Kochman J, Somi S, Esposito G, Mercone G, Mejia-Renteria H, Ronco F, Botker HE, Wijns W, Christiansen EH, Holm NR. Diagnostic Performance of In-Procedure Angiography-Derived Quantitative Flow Reserve Compared to Pressure-Derived Fractional Flow Reserve: The FAVOR II Europe-Japan Study. J Am Heart Assoc. 2018 Jul 6; 7(14): e009603. 147. Wiedenroth CB, Ghofrani HA, Adameit MSD, Breithecker A, Haas M, Kriechbaum S, Rieth A, Hamm CW, Mayer E, Guth S, Liebetrau C. Sequential treatment with riociguat and balloon pulmonary angioplasty for patients with inoperable chronic thromboembolic pulmonary hypertension. Pulm Circ. 2018 Jul-Sep; 8(3): 2045894018783996. 148. Wiedenroth CB, Olsson KM, Guth S, Breithecker A, Haas M, Kamp JC, Fuge J, Hinrichs J, Roller F, Hamm C, Mayer E, Ghofrani A, Meyer BC, Liebetrau C. Balloon pulmonary angioplasty for inoperable patients with chronic thromboembolic disease. Pulm Circ. 2018 Jan-Mar; 8(1): 2045893217753122. 149. Wöhrle J, Nef HM, Naber C, Achenbach S, Riemer T, Mehilli J, Münzel T, Schneider S, Markovic S, Seeger J, Rottbauer W, Pfannebecker T, Richardt G, Zahn R, Gori T, Kastner J, Schmermund A, Hamm CW. Predictors of early scaffold thrombosis: results from the multicenter prospective German-Austrian ABSORB RegIstRy. Coron Artery Dis. 2018 Aug; 29(5): 389-396.

Buchartikel 1. Haider KH and Aslam M. Cell-free therapy with stem cell secretions: protection, repair, and regeneration of the injured myocardium. In: Stem Cells – From Hype to Real Hope. Haider KH, Aziz S (Eds.), 1st Edition, pp 34 – 70, De Gruyter, 2018. 2. Klingenberg R and Müller-Ladner U. Chapter: 25.2: Mechanisms of inflammation. In: The ESC Textbook of Cardiovascular Medicine. Camm AJ, Lüscher TF, Maurer G, Serruys PW. (Eds.), 3rd Edition, Oxford University Press, 2018. 3. Sperzel J. Chapter 38.23: Pacemakers in children and adolescents. In: The ESC Textbook of Cardiovascular Medicine. Camm AJ, Lüscher TF, Maurer G, Serruys PW. (Eds.), 3rd Edition, Oxford University Press, 2018. 4. Haider KH and Aslam M. Cell-free therapy with stem cell secretions: protection, repair, and regeneration of the injured myocardium. In: Stem Cells – From Hype to Real Hope. Haider KH, Aziz S (Eds.), 1st edition pp 34 – 70, DE GRUYTER, 2018. 5. Klingenberg R and Müller-Ladner U (2018) Section: Rheumatoid arthritis and the heart. Chapter: 25.2 Title: Mechanisms of inflammation. The ESC Textbook of Cardiovascular Medicine 3rd edition. Camm AJ, Lüscher TF, Maurer G, Serruys PW. (eds). Oxford University Press; DOI: 10.1093/ med/9780198784906.003.0270, Print ISBN-13: 9780198784906. 6. Fischer-Rasokat U., Hamm C. Clinical symptoms of stable ischemic heart disease. In: The ESC Textbook of Cardiovascular Medicine. Camm AJ, Luscher TF, Maurer G and Serruys PW (eds), 3. Edition, Section 31.7. OXFORD UNIV PR, 2018. 7. Fischer-Rasokat U., Dill T., Hamm C. Koronare Herzkrankheit. In: Duale Reihe Innere Medizin. 4. überarbeitete Auflage, Kapitel 4 (Seiten 61-81). Thieme Verlag, 2018.

Preise 1. DGK Young Investigator Award Herzinsuffizienz 2. Platz: Jakob Lorenz et al. (Gießen) 2. DGK Young Investigator Award Koronare Herzerkrankung 2. Platz: Jan Sebastian Wolter et al. (Bad Nauheim) 3. Publikationspreis des Vereins der Freunde und Förderer der Kerckhoff-Klinik e.V. 1. Platz: Dr.med. Andreas Rieth gemeinsam mit Dr. med. Steffen Kriechbaum (bd. Bad Nauheim)

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Herzzentrum Herzchirurgie Komm. Direktor: Prof. Dr. med. M. Schönburg

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PUBLIKATIONEN 2018

Originalarbeiten & Übersichtsarbeiten 1. Koehne J, Doss M, Kim WK, Walther T.

Pusher preventing maximum expansion of transfemoral transcatheter valves. Interact Cardiovasc Thorac Surg. 2018 Feb 1;26(2):355-356.

2. Arsalan M, Weferling M, Hecker F, Filardo G, Kim WK, Pollock BD, Van Linden A, Arsalan-Werner A, Renker M, Doss M, Kalbas S, Hamm CW, Liebetrau C, Mack MJ, Walther T. TAVI risk scoring using established versus new scoring systems: role of the new STS/ACC model. EuroIntervention. 2018 Jan 20;13(13):1520-1526.

3. Kim WK, Gaede L, Husser O, Liebetrau C, Renker M, Rolf A, Fischer-Rasokat U, Möllmann S, Blumen-stein J, Guenther E, Van Linden A, Arsalan M, Doss M, Loders S, Arnold M, Hamm CW, Walther T, Achenbach S, Möllmann H. Computed Tomography for Diagnosis and Classification of Bicuspid Aor-tic Valve Disease in Transcatheter Aortic Valve Replacement.

JACC Cardiovasc Imaging. 2018 Oct;11(10):1539-1540. 4. Arsalan M, Kim WK, Van Linden A, Liebetrau C, Pollock BD, Filardo G, Renker M, Möllmann H, Doss M, Fischer-Rasokat U, Skwara A, Hamm CW, Walther T. Predictors and outcome of conversion to cardiac surgery during transcatheter aortic valve implantation. Eur J Cardiothorac Surg. 2018 Aug 1;54(2):267-272. 5. Kim WK, Möllmann H, Liebetrau C, Renker M, Rolf A, Simon P, Van Linden A, Arsalan M, Doss M,

Hamm CW, Walther T. The ACURATE neo Transcatheter Heart Valve: A Comprehensive Analysis of Predictors of Procedural Outcome. JACC Cardiovasc Interv. 2018 Sep 10;11(17):1721-1729.

6. Kim WK, Renker M, Rolf A, Liebetrau C, Van Linden A, Arsalan M, Doss M, Rieck J, Opolski MP, Möll-mann H, Walther T, Hamm CW. Accuracy of device landing zone calcium volume measurement with contrast-enhanced multidetector computed tomography. Int J Cardiol. 2018 Jul 15;263:171-176.

7. Cetinkaya A, Skwara W, Hein S, Bramlage P, Schönburg M, Richter M. Angiosarcoma of the right atrium with extension to the superior and inferior vena cavae. J Card Surg. 2018 Dec;33(12):806-807. 8. Sprengel A, Skwara W, Ziegelhöffer T, Cetinkaya A, Schönburg M, Richter M. Combined mitral valve repair and heart transplantation. Clin Case Rep. 2018 Feb 7;6(4):564-568. 9. Burger H, Ziegelhoeffer T, Schoenburg M, Richter M. Recurrent Bacteremia After Heart

Transplantation Due to Abandoned Lead Fragment in an Anonymous Vein-A Case Report. Transplant Proc. 2018 Dec;50(10):4071-4074.

10. Annual report 2015 of the German cardiac pacemaker and defibrillator register-Part 1: pace makers. Markewitz A; Bundesfachgruppe Herzschrittmacher. Herzschrittmacherther Elektrophysiol. 2018 Mar;29(1):84-99.

11. Sondenextraktion. Burger H, Z Herz-Thorax-Gefäßchirurgie 32(2):93-102, 2018 12. Einsatz des tragbaren Kardioverter-Defibrillators nach kardiochirurgischen Eingriffen. Burger H,

Schmitt J, Knaut M, Eitz T, Starck CT, Hakmi S, Siebel A, Böning A. Z Herz- Thorax- Gefäßchir, 32(4):286-299, 2018

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Rheumatologie & Klinische Immunologie Direktor: Univ.- Prof. Dr. med. U. Müller-Ladner

Physikalische Medizin & Osteologie Direktor: Univ.- Prof. Dr. med. U. Lange

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Rheumatologie & Klinische Immunologie Direktor: Univ.- Prof. Dr. med. U. Müller-Ladner

Physikalische Medizin & Osteologie Direktor: Univ.- Prof. Dr. med. U. Lange

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Publikationsbericht 2018 Rheumatologie & klinische Immunologie Physikalische Medizin & Osteologie Originalarbeiten 1. Arnold MB, Khanna D, Denton CP, van Laar JM, Frech TM, Anderson ME, Baron M, Chung L, Fierlbeck

G, Lakshminarayanan S, Allanore Y, Riemekasten G, Steen V, Müller-Ladner U, Spotswood H, Burke L, Siegel J, Jahreis A, Furst DE, Pope JE. Patient acceptable symptom state in scleroderma: results from the tocilizumab compared with placebo trial in active diffuse cutaneous systemic sclerosis. Rheumatology 2018; 57:152-157

2. Benjamin C, Carlo Alberto S, Rosaria T, Tobias A, Zahir A, Tadej A, Lorenzo B, Andrea D, Aurelien G, Vera G, Éric H, Thomas K, David L, Gemma L, Pia M, Müller-Ladner U, Simona R, Ana R, Sander W T, van Vollenhoven R F, Ana V, Stefano B, Eurico FJ, Ilaria G, Matthias S, Vanessa S, Maurizio C, Marta M, Rebecca FB. Mixed connective tissue disease: state of the art on clinical practice guidelines. RMD Open 2018; 4 (Suppl 1):e000783

3. Beyer C, Huscher D, Ramming A, Bergmann C, Avouac J, Guiducci S, Meier F, Vettori S, Siegert E, Jaeger VK, Maurer B, Riemekasten G, Walker U, Müller-Ladner U, Valentini G, Matucci-Cerinic M, Allanore Y, Distler O, Schett G, Distler JHW. Elevated serum levels of sonic hedgehog are associated with fibrotic and vascular manifestations in systemic sclerosis. Ann Rheum Dis 2018; 77:626-628

4. Dischereit G, Goronzy J-E, Müller-Ladner U, Fetaj S, Lange U. Wirkeffekte serieller Heiltorfbäder bei entzündlich-rheumatischen und degenerativen Erkrankungen. Z Rheumatol 2018 (epub DOI: 10.1007/s00393-018-0582-7; ahead of print)

5. Fiehn C, Holle J, Iking-Konert C, Leipe J, Weseloh C, Frerix M, Alten R, Behrens F, Baerwald C, Braun J, Burkhardt H, Burmester G, Detert J, Gaubitz M, Gause A, Gromnica-Ihle E, Kellner H, Krause A, Kui-pers J, Lorenz HM, Müller-Ladner U, Nothacker M, Nüsslein H, Rubbert-Roth A, Schneider M, Schulze-Koops H, Seitz S, Sitter H, Specker C, Tony HP, Wassenberg S, Wollenhaupt J, Krüger K. S2e Leitli-nie: Behandlung der rheumatoiden Arthritis mit krankheitsmodifizierenden Medikamenten. Z Rheu-matol 2018; 77(Suppl 2):35-53

6. Herrick AL, Peytrignet S, Lunt M, Pan X, Hesselstrand R, Mouthon L, Silman AJ, Dinsdale G, Brown E, Czirják L, Distler JHW, Distler O, Fligelstone K, Gregory WJ, Ochiel R, Vonk MC, Ancuţa C, Ong VH, Farge D, Hudson M, Matucci-Cerinic M, Balbir-Gurman A, Midtvedt Ø, Jobanputra P, Jordan AC, Ste-vens W, Moinzadeh P, Hall FC, Agard C, Anderson ME, Diot E, Madhok R, Akil M, Buch MH, Chung L, Damjanov NS, Gunawardena H, Lanyon P, Ahmad Y, Chakravarty K, Jacobsen S, MacGregor AJ, Mc-Hugh N, Müller-Ladner U, Riemekasten G, Becker M, Roddy J, Carreira PE, Fauchais AL, Hachulla E, Hamilton J, İnanç M, McLaren JS, van Laar JM, Pathare S, Proudman SM, Rudin A, Sahhar J, Coppere B, Serratrice C, Sheeran T, Veale DJ, Grange C, Trad GS, Denton CP. Patterns and predictors of skin score change in early diffuse systemic sclerosis from the European Scleroderma Observational Study. Ann Rheum Dis 2018; 77:563-570

7. Jaeger VK, Valentini G, Hachulla E, Cozzi F, Distler O, Airó P, Czirják L, Allanore Y, Siegert E, Rosato E, Matucci-Cerinic M, Caimmi C, Henes J, Carreira PE, Smith V, Del Galdo F, Denton CP, Ullman S, Langhe E, Riccieri V, Alegre-Sancho JJ, Rednic S, Müller-Ladner U, Walker UA, and EUSTAR co-authors. Smoking in Systemic Sclerosis: a Longitudinal European Scleroderma Trials and Research Group Study. Arthritis Rheumatol 2018; 70:1829-1834

8. Jaeger VK, Distler O, Maurer B, Czirjak L, Lorand V, Valentini G, Vettori S, Del Galdo F, Abignano G, Denton C, Nihtyanova S, Allanore Y, Avouac J, Riemekasten G, Siegert E, Huscher D, Matucci-Cerinic M, Guiducci S, Frerix M, Tarner IH, Garay Toth B, Fankhauser B, Umbricht J, Zakharova A, Mihai C, Cozzi F, Yavuz S, Hunzelmann N, Rednic S, Vacca A, Schmeiser T, Riccieri V, Garcia de la Pena Lefe-bre P. Gabrielli A, Krummel-Lorenz B, Martinovic D, Ancuta C, Smith V, Müller-Ladner U, Walker UA. Functional disability and its predictors in systemic sclerosis: a study from the DeSScipher project within the EUSTAR group. Rheumatology 2018; 57:441-450

9. Johnson SR, Soowamber ML, Fransen J, Khanna D, Van Den Hoogen F, Baron M, Matucci-Cerinic M, Denton CP, Medsger TA Jr, Carreira PE, Riemekasten G, Distler J, Gabrielli A, Steen V, Chung L, Silver R, Varga J, Müller-Ladner U, Vonk MC, Walker UA, Wollheim FA, Herrick A, Furst DE, Czirjak L, Kowal-Bielecka O, Del Galdo F, Cutolo M, Hunzelmann N, Murray CD, Foeldvari I, Mouthon L, Damjanov N, Kahaleh B, Frech T, Assassi S, Saketkoo LA, Pope JE. There is a need for new systemic sclerosis sub-set criteria. A content analytic approach. Scand J Rheumatol 2018; 47:62-70

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10. Khanna D, Denton CP, Lin CJ, van Laar JM, Frech TM, Anderson ME, Baron M, Chung L, Fierlbeck G, Lakshminarayanan S, Allanore Y, Pope JE, Riemekasten G, Steen V, Müller-Ladner U, Spotswood H, Burke L, Siegel J, Jahreis A, Furst DE. Safety and efficacy of subcutaneous tocilizumab in systemic sclerosis: results from the open-label period of a phase II randomised controlled trial (faSScinate). Ann Rheum Dis 2018; 77:212-220

11. Lambova S, Müller-Ladner U. Nailfold Capillaroscopy Within and Beyond the Scope of Connective Tissue Diseases. Curr Rheumatol Rev 2018; 14:12-21

12. Lambova S, Müller-Ladner U. Capillaroscopic Findings in Primary Fibromyalgia. Curr Rheumatol Rev 2018; 14:36-41 13. Lambova SN, Müller-Ladner U. Osteoarthritis - Current Insights in Pathogenesis, Diagnosis and

Treatment. Curr Rheumatol Rev. 2018; 14:91-97 14. Lange U, Goronzy J-E, Mueller-Ladner U, Frommer K, Dischereit G. Anti-inflammatory effect of serial

mud baths in rheumatoid arthritis and ankylosing spondylitis. IOSR J Pharmacy Biol Sci 2018; 2: 59-63 15. Lange U. Der klinische Blick schafft Klarheit. Bandscheiben im Röntgen weiß - in der Knochendichte-

messung schwarz. Orthopädie & Rheuma 2018; 21:66 16. Lange U, Müller-Ladner U, Dischereit G. Milde Ganzkörper-Überwärmungstherapie bei Morbus

Bechterew. Morbus-Bechterew-Journal 2018; 153:1-3 17. Lange U, Sperling M, Richter-Bastian K, Dischereit G, Müller-Ladner U, Tarner ICH. Wirksamkeit einer

manuellen Mobilisation der Brustwirbelsäule bei Morbus Bechterew-Patienten. Morbus-Bechterew-Journal 2018; 155:28-29

18. Lange U, Reuss-Borst M, Dischereit G. Kasuistik einer Oxalose-Arthropathie und aktueller Überblick. Akt Rheumatol 2018; 43:224-227

19. Lange U, Bogensperger S, Tarner ICH, Müller-Ladner U. The effects of a single carbon dioxide and hot water hand bath on acral perfusion in systemic sclerosis – a randomized, clinical study. JSRD 2018 (epub, DOI: 10.1177/2397198318819919; ahead of print)

20. Lange U. Sarkopenie und Frailty beim älteren Rheumapatienten. Z Rheumatol 2018; 77:379-384 21. Mihai C, Antic M, Dobrota R, Bonderman D, Chadha-Boreham H, Coghlan JG, Denton CP, Doelberg M,

Grünig E, Khanna D, McLaughlin VV, Müller-Ladner U, Pope JE, Rosenberg DM, Seibold JR, Vonk MC, Distler O. Factors associated with disease progression in early-diagnosed pulmonary arterial hyper-tension associated with systemic sclerosis: longitudinal data from the DETECT cohort. Ann Rheum Dis 2018; 77:128-132

22. Müller-Ladner U. In label - was ist überhaupt erlaubt? Z Rheumatol 2018; 77:557-558 23. Neumann E, Schwarz MC, Hasseli H, Hülser M-L, Classen S, Sauerbier M, Rehart S, Müller-Ladner U.

Tetraspanin CD82 affects migration, attachment and invasion of rheumatoid arthritis synovial fibroblasts. Ann Rheum Dis 2018; 77:1619-1626

24. Neumann E, Hasseli R, Lange U, Muller-Ladner U. The Role of Extracellular Nucleic Acids in Rheu-matoid Arthritis. Curr Pharm Biotechnol 2018;19:1182-88

25. Neumann E, Frommer K, Diller M, Müller-Ladner U. Rheumatoide Arthritis. Z Rheumatol 2018; 77:769-775

26. Peytrignet S, Denton CP, Lunt M, Hesselstrand R, Mouthon L, Silman A, Pan X, Brown E, Czirják L, Distler JHW, Distler O, Fligelstone K, Gregory WJ, Ochiel R, Vonk M, Ancuta C, Ong VH, Farge D, Hudson M, Matucci-Cerinic M, Balbir-Gurman A, Midtvedt Ø, Jordan AC, Stevens W, Moinzadeh P, Hall FC, Agard C, Anderson ME, Diot E, Madhok R, Akil M, Buch MH, Chung L, Damjanov N, Gunawar-dena H, Lanyon P, Ahmad Y, Chakravarty K, Jacobsen S, MacGregor AJ, McHugh N, Müller-Ladner U, Riemekasten G, Becker M, Roddy J, Carreira PE, Fauchais AL, Hachulla E, Hamilton J, Inanç M, McLa-ren JS, van Laar JM, Pathare S, Proudman S, Rudin A, Sahhar J, Coppere B, Serratrice C, Sheeran T, Veale DJ, Grange C, Trad GS, Herrick AL. Disability, fatigue, pain and their associates in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study. Rheumatology 2018; 57:370-381

27. Rieth AJ, Richter MJ, Berkowitsch A, Frerix M, Tarner IH, Mitrovic V, Hamm CW. Intravenous sildenafil acutely improves hemodynamic response to exercise in patients with connective tissue disease. PLoS One 2018;13(9):e0203947

28. Roodenrijs NMT, de Hair MJH, van der Goes MC, Jacobs JWG, Welsing PMJ, van der Heijde D, Ale-taha D, Dougados M, Hyrich KL, McInnes IB, Müller-Ladner U, Senolt L, Szekanecz Z, van Laar JM, Nagy G. Characteristics of difficult-to-treat rheumatoid arthritis: results of an international survey. Ann Rheum Dis 2018; 77:1705-1709

29. Szekanecz Z, van Laar JM, Nagy G. Characteristics of difficult-to-treat rheumatoid arthritis: results of an international survey. Ann Rheum Dis 2018; 77:1705-1709

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30. Schaepe K, Bhandari DR, Werner J, Henss A, Pirkl A, Kleine-Boymann M, Rohnke M, Wenisch S, Neu-mann E, Janek J, Spengler B. Imaging of Lipids in Native Human Bone Sections Using TOF-Secondary Ion Mass Spectrometry, Atmospheric Pressure Scanning Microprobe Matrix-Assisted Laser Desorption/Ionization Orbitrap Mass Spectrometry, and Orbitrap-Secondary Ion Mass Spectrometry. Anal Chem 2018; 90:8856-64.

31. Smith V, Scirè Carlo A, Talarico R, Airò P, Alexander T, Allanore Y, Bruni C, Codullo V, Dalm V, de Vries-Bouwstra J, della Rossa A, Distler O, Galetti I, Launay D, Lepri G, Mathian A, Ruaro B, Sulli A, Vandecasteele E, Vanhaecke A, Vanthuyne M, van den Hoogen F, van Vollenhoven R, Voskuyl A, Zannata E, Bombardieri S, Burmester G, Fonseca JE, Frank C, Hachulla É, Houssiau F, Müller-Ladner Ulf, Schneider M, van Laar J, Vieira A, Cutolo M, Mosca M, Matucci Cerinic M. Systemic Sclerosis: State of the art on Clinical Practice Guidelines. RMD Open 2018; 4(Suppl 1):e000782

32. Thomalla M, Schmid A, Neumann E, Pfefferle PI, Müller-Ladner U, Schäffler A, Karrasch T. Evidence of an Anti-inflammatory Toll-like Receptor 9 (TLR 9) Pathway in Adipocytes. J Endocrinol 2018 (epub, ahead of print)

33. Tsiklauri L, Werner J, Kampschulte M, Frommer KW, Berninger L, Irrgang M, Glenske K, Hose D, El Khassawna T, Pons-Kühnemann J, Rehart S, Wenisch S, Müller-Ladner U, Neumann E. Visfatin alters the cytokine and matrix-degrading enzyme profile during osteogenic and adipogenic MSC differen-tiation. Osteoarthritis Cartilage 2018; 26:1225-1235

34. Uhrmann M, Lange U, Gissel C. Kosten-Nutzwert-Analyse der Biosimilar-Therapie bei ankylosieren-der Spondylitis in Deutschland. Akt Rheumatol 2018; 43:470-478

35. Wegner F, Müller-Ladner U, Meier FMP. Reply: Missing wrists in a patient with rheumatoid arthritis. A matter of compliance. J Rheumatol 2018; 45:875

Übersichtsarbeiten 1. Adler S, Huscher D, Siegert E, Allanore Y, Czirják L, DelGaldo F, Denton CP, Distler O, Frerix M,

Matucci-Cerinic M, Müller-Ladner U, Tarner IH, Valentini G, Walker UA, Villiger PM, Riemekasten G; EUSTAR co-workers on behalf of the DeSScipher project research group within the EUSTAR net-work. Systemic sclerosis associated interstitial lung disease - individualized immunosuppressive therapy and course of lung function: results of the EUSTAR group. Arthritis Res Ther 2018; 20:17

2. Braun J, Lorenz HM, Müller-Ladner U, Schneider M, Schulze-Koops H, Specker C, Strangfeld A, Wag-ner U, Dörner T. Revised version of the statement by the DGRh on biosimilars-update 2017. Z Rheu-matol 2018; 77:81-90

3. Cutolo M, Melsens K, Herrick AL, Foeldvari I, Deschepper E, De Keyser F, Distler O, Ingegnoli F, Mostmans Y, Müller-Ladner U, Pizzorni C, Riccieri V, Ruaro B, Sulli A, Trombetta AC, Vanhaecke TA, Smith V, EULAR Study Group on Microcirculation in Rheumatic Diseases. Reliability of simple capilla-roscopic definitions in describing capillary morphology in rheumatic diseases. Rheumatology 2018; 57:757-759

4. Cutolo M, Melsens K, Wijnant S, Ingegnoli F, Thevissen K, De Keyser F, Decuman S, Müller-Ladner U, Piette Y, Riccieri V, Ughi N, Vandecasteele E, Vanhaecke A, Smith V. Nailfold capillaroscopy in sys-temic lupus erythematosus: A systematic review and critical appraisal. Autoimmun Rev 2018; 17:344-352

5. Dischereit G, Lange U. Rheuma und Ochronose (Alkaptonurie). Akt Rheumatol 2018; 43:228-230 6. Hermann W, Lambova S, Müller-Ladner U. Current treatment options for osteoarthritis. Curr

Rheumatol Rev 2018; 14:108-116 7. Hülser LM, Frommer K, Müller-Ladner U. Die Rolle des Metabolismus und metabolisch relevanter

Faktoren in der Pathophysiologie rheumatischer Erkrankungen. Akt Rheumatol 2018; 43:207-214 8. Kay J, Schoels MM, Dörner T, Emery P, Kvien TK, Smolen JS, Breedveld FC; Task Force on the Use

of Biosimilars to Treat Rheumatological Diseases (…Müller-Ladner U…) Consensus-based recommen-dations for the use of biosimilars to treat rheumatological diseases. Ann Rheum Dis 2018; 77:165-174

9. Lambova SN, Müller-Ladner U. Inhomogene kapillarmikroskopische Befunde bei systemischer Sklerodermie. Wien Med Wschr 2018; 168:248-249

10. Lambova S, Müller-Ladner U. Nailfold Capillaroscopy in Rheumatology. Curr Rheumatol Rev 2018; 14:2-4

11. Lambova SN, Müller-Ladner U. Nailfold Capillaroscopy of Fingers and Toes - Variations of Normal. Curr Rheumatol Rev 2018; 14:28-35

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12. Lange U, Richter-Bastian K, Dischereit G. Rheumatoide Arthritis – Funktionserhalt und Rolle der Be-wegungstherapie. internistische praxis 2018; 59:568-573

13. Lange U, Richter-Bastian K, Dischereit G. Im Blickpunkt: Rheumatoide Arthritis. Funktionserhalt und Rolle der Bewegungstherapie. tägliche praxis 2018; 60:568-573

14. Lange U. Editorial Interdisziplinäre Rheumatologie. Akt Rheumatol 2018; 43:413 15. Lange U, Dischereit G. Wirkeffekte differenter iterativer Ganzkörper-Hyperthermie-Verfahren auf

Schmerzen und Zytokine bei rheumatischen Erkrankungen – eine aktuelle Literaturübersicht. Akt Rheumatol 2018; 43:479-482

16. Lange U, Rehart S. Physikalische Therapieoptionen bei rheumatologischen Erkrankungen: Was gibt es an Evidenz? Der Orthopäde 2018; 47:926-932

17. Müller-Ladner U. Off to On: Biologikatherapie bei systemisch-immunologischen Erkrankungen. Z Rheumatol 2018; 77:10-11

18. Müller-Ladner U. Laudatio zum 70. Geburtstag von Prof. Dr. med. Steffen Gay Z Rheumatol 2018; 77:177-178 19. Müller-Ladner U, Fischer-Betz R. German Pregnancy Register "Rhekiss". Dtsch Arztebl Int 2018; 115:112 20. Müller-Ladner U. Rheumatologische Forschungsnetzwerke in Deutschland. Z Rheumatol 2018; 77(Suppl. 1):S1-S3 21. Ndosi M, Alcacer-Pitarch B, Allanore Y, Del Galdo F, Frerix M, Diaz-Garcia S, Hesselstrand R, Kendall

C, Matucci-Cerinic M, Müller-Ladner U, Sandqvist G, Torrente-Segarra V, Schmeiser T, Sierakowska M, Sierakowska J, Sierakowski S, Redmond A. Common measure of quality of life for people with systemic sclerosis across seven European countries: a cross sectional study. Ann Rheum Dis 2018; 77:1032–1038

22. Pfeil A, Lehmann G, Lange U. Update DVO-Leitlinie 2017 „Prophylaxe, Diagnostik und Therapie der Osteoporose bei postmenopausalen Frauen und Männern“ – Was ändert sich, was bleibt für den Rheumatologen? Z Rheumatol 2018; 77:759-763

23. Richter K, Müller-Ladner U, Dischereit G, Lange U. Potentials and limits of physiotherapy in osteo-arthritis. Curr Rheumatol Rev 2018; 14:117-122

24. Schett G, Bozec A, Bekeredjian-Ding I, Chang HD, David JP, Dorner T, Grassel S, Gunzer M, Manz R, Mei H, Mielenz D, Muller-Ladner U, Neumann E, Radbruch A, Richter W, Straub RH. New insights into the function of bone marrow. Z Rheumatol 2018; 77:4-7

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Buchartikel 1. Lange U. Physikalische Schmerztherapie der Osteoporose. In: Fachwissen Osteologie. Kurth A.,

Lange U. (Hrsg.), pp 127-129, Elsevier, 2018 2. Lange U. Knochen und Entzündung: osteoimmunologische Aspekte. In: Fachwissen Osteologie.

Kurth A., Lange U. (Hrsg.), pp 25-32, Elsevier, 2018 3. Lange U, Dischereit G. Knochenstoffwechselveränderungen bei entzündlich-rheumatischen

Erkrankungen. In: Fachwissen Osteologie. Kurth A., Lange U. (Hrsg.), pp 102-105, Elsevier, 2018 4. Lange U, Dischereit G. Alkaptonurie – Ochronose. In: Fachwissen Osteologie. Kurth A., Lange U.

(Hrsg.), pp 293-295, Elsevier 2018 5. Lange U. Fall 40: Schenkelhalsfraktur bei laborchemisch inaktivem Morbus Paget. 50 Fälle

Osteologie. Roth, Peters, Siggelkow (Hrsg.), pp 213-216, Schattauer, 2018 6. Lange U. Elsevier Essentials Rheumatologie. 9.3 Physikalische Therapie. Pfeil A, Oelzner P,

Böttcher J, Jung C, Wolf G (Hrsg.), pp 147-151, Elsevier, 2018 7. Müller-Ladner U, Hügle T, Zeidler H, Michel B. Differenzialdiagnose lokalisierter rheumatischer

Schmerzzustände. In: Differenzialdiagnose rheumatischer Erkrankungen. Zeidler H, Michel B (Hrsg.) Springer, 2018

8. Müller-Ladner U. Systemische Sklerose. In: Differenzialdiagnostik und Differenzialtherapie in der Inneren Medizin. 2. Aufl. Brunkhorst R, Schölmerich J (Hrsg.) Elsevier, 2018

9. Müller-Ladner U. Systemischer Lupus Erythematodes. In: Differenzialdiagnostik und Differenzial-therapie in der Inneren Medizin. 2. Aufl. Brunkhorst R, Schölmerich J (Hrsg.) Elsevier, 2018.

10. Müller-Ladner U. Vaskulitiden. In: Differenzialdiagnostik und Differenzialtherapie in der Inneren Medizin. 2. Aufl. Brunkhorst R, Schölmerich J (Hrsg.) Elsevier, 2018

11. Neumann E, Frommer K, Müller-Ladner U. Oxford Textbook of Rheumatology, 4th Edition. Chapter 4.15: Adipocytokines modulate inflammatory and acute phase responses. Oxford: Oxford University Press, 2018.

12. Dinser R, Hermann W, Müller-Ladner U. Wurzelkompressionssyndrom In: Differenzialdiagnostik und Differenzialtherapie in der Inneren Medizin. 2. Aufl. Brunkhorst R, Schölmerich J (Hrsg.) Elsevier, 2018

Bücher 1. Kurt A, Lange U (Hrsg.). Fachwissen Osteologie. 1. Auflage, Elsevier, 2018 (ISBN 978-3-437-22102-6) 4th Edition

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Lungenzentrum Thoraxchirurgie Direktor: Prof. Dr. med. E. Mayer

Allgemeine Pneumologie & Pneumologische Onkologie Direktor: Univ.- Prof. Dr. med. A. H. Ghofrani

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Lungenzentrum Thoraxchirurgie Direktor: Prof. Dr. med. E. Mayer

Allgemeine Pneumologie & Pneumologische Onkologie Direktor: Univ.- Prof. Dr. med. A. H. Ghofrani

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Thoraxchirurgie

Publikationen 2018 Originalarbeiten & Übersichtsarbeiten 1. Wilkens H, Konstantinides S, Lang IM, Bunck AC, Gerges M, Gerhardt F, Grgic A, Grohe C, Guth S,

Held M, Hinrichs JB, Hoeper MM, Klepetko W, Kramm T, Kruger U, Lankeit M, Meyer BC, Olsson KM, Schafers HJ, Schmidt M, Seyfarth HJ, Ulrich S, Wiedenroth CB, Mayer E. Chronic thromboembolic pulmonary hypertension (CTEPH): Updated Recommendations from the Cologne Consensus Confer-ence 2018. Int J Cardiol 2018; 272S: 69-78.

2. Wiedenroth CB, Olsson KM, Guth S, Breithecker A, Haas M, Kamp JC, Fuge J, Hinrichs JB, Roller F, Hamm CW, Mayer E, Ghofrani HA, Meyer BC, Liebetrau C. Balloon pulmonary angioplasty for inoper-able patients with chronic thromboembolic disease. Pulm Circ 2018; 8: 2045893217753122.

3. Wiedenroth CB, Ghofrani HA, Adameit MSD, Breithecker A, Haas M, Kriechbaum S, Rieth A, Hamm CW, Mayer E, Guth S, Liebetrau C. Sequential treatment with riociguat and balloon pulmonary angio-plasty for patients with inoperable chronic thromboembolic pulmonary hypertension. Pulm Circ 2018; 8: 2045894018783996.

4. Stanzel RDP, Gehron J, Wolff M, Striegl N, Roth P, Boedeker RH, Scheibelhut C, Herrmann J, Welters I, Mayer E, Scheffler M. International survey on the perioperative management of pulmonary en-darterectomy: the perfusion perspective. Perfusion 2018; 33: 53-61.

5. Kriechbaum SD, Wiedenroth CB, Wolter JS, Hutz R, Haas M, Breithecker A, Roller FC, Keller T, Guth S, Rolf A, Hamm CW, Mayer E, Liebetrau C. N-terminal pro-B-type natriuretic peptide for monitoring after balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension. J Heart Lung Transplant 2018; 37: 639-646.

6. Kriechbaum SD, Wiedenroth CB, Keller T, Wolter JS, Ajnwojner R, Peters K, Haas MA, Roller FC, Brei-thecker A, Rieth AJ, Guth S, Rolf A, Bandorski D, Hamm CW, Mayer E, Liebetrau C. Dynamics of high-sensitivity cardiac troponin T during therapy with balloon pulmonary angioplasty for chronic throm-boembolic pulmonary hypertension. PLoS One 2018; 13: e0204683.

7. Kramm T, Wilkens H, Fuge J, Schafers HJ, Guth S, Wiedenroth CB, Weingard B, Huscher D, Pittrow D, Cebotari S, Hoeper MM, Mayer E, Olsson KM. Incidence and characteristics of chronic thromboem-bolic pulmonary hypertension in Germany. Clin Res Cardiol 2018; 107: 548-553.

8. Klok FA, Barco S, Konstantinides SV, Dartevelle P, Fadel E, Jenkins D, Kim NH, Madani M, Matsubara H, Mayer E, Pepke-Zaba J, Delcroix M, Lang IM. Determinants of diagnostic delay in chronic throm-boembolic pulmonary hypertension: results from the European CTEPH Registry. Eur Respir J 2018; 52.

9. Kim NH, Mayer E. Pulmonary endarterectomy and the cost of patient refusal. Eur Respir J 2018; 52. 10. Guth S, Wiedenroth CB, Wollenschlager M, Richter MJ, Ghofrani HA, Arlt M, Mayer E. Short-term

venoarterial extracorporeal membrane oxygenation for massive endobronchial hemorrhage after pulmonary endarterectomy. J Thorac Cardiovasc Surg 2018; 155: 643-649.

11. Guth S, Wiedenroth CB, Rieth A, Richter MJ, Gruenig E, Ghofrani HA, Arlt M, Liebetrau C, Prufer D, Rolf A, Hamm CW, Mayer E. Exercise right heart catheterisation before and after pulmonary en-darterectomy in patients with chronic thromboembolic disease. Eur Respir J 2018; 52.

12. Bazmpani MA, Arvanitaki A, Toumpourleka M, Pitsiou G, Panagiotidou E, Mouratoglou SA, Sianos G, Hadjimiltiades S, Pitsis A, Mayer E, Stanopoulos I, Karvounis H, Giannakoulas G. Epidemiology and management of chronic thromboembolic pulmonary hypertension: experience from two expert cen-ters. Hellenic J Cardiol 2018; 59: 16-23

13. Bazmpani MA, Arsos G, Zarogoulidis P, Doumas A, Dimitroulas T, Sianos G, Hadjimiltiades S, Kouskouras K, Mayer E, Karvounis H, Giannakoulas G. A case of sarcoidosis-associated pulmonary hypertension masquerading as chronic thromboembolic pulmonary hypertension. Pulm Circ 2018; 8: 2045894018768289.

14. Richter MJ, Harutyunova S, Bollmann T, Classen S, Gall H, Gerhardt Md F, Grimminger F, Grimminger J, Grünig E, Guth S, Halank M, Heine A, Hoeper MM, Klose H, Lange TJ, Meyer K, Neurohr C, Nicko-laus K, Olsson KM, Opitz CF, Rosenkranz S, Seyfarth HJ, Warnke C, Wiedenroth C, Ghofrani HA, Ewert R. Long-term safety and outcome of intravenous treprostinil via an implanted pump in pulmonary hypertension. J Heart Lung Transplant. 2018 Oct;37(10):1235-1244

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Gefäßzentrum Direktor: Dr. med. S. Classen

Gefäßchirurgie & Angiologie

35

Gefäßzentrum Direktor: Dr. med. S. Classen

Gefäßchirurgie & Angiologie

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Gefäßzentrum

Publikationen 2018 Originalarbeiten & Übersichtsarbeiten 1. Proposed phase 2/ step 2 in-vitro test on basis of EN 14561 for standardised testing of the wound

antiseptics PVP-iodine, chlorhexidine digluconate, polihexanide and octenidine dihydrochloride Schedler K, Assadian O, Brautferger U, Müller G, Koburger T, Classen S, Kramer A.

BMC Infect Dis. 2018 Feb 13;18(1):143. 2. Percutaneous endovascular treatment of infrainguinal PAOD: Results of the PSI register study in 74 German vascular centers. Gefasschirurgie. 2018;22(Suppl 1):17-27. Behrendt CA1, Heidemann F1, Haustein K1, Grundmann RT2, Debus ES1; PSI Collaborators. 3. Long-term safety and outcome of intravenous treprostinil via an implanted pump in pulmonary hypertension. Richter MJ, Harutyunova S, Bollmann T, Classen S, Gall H, Gerhardt Md F, Grimminger F, Grimminger J, Grünig E, Guth S, Halank M, Heine A, Hoeper MM, Klose H, Lange TJ, Meyer K, Neurohr C, Nickolaus K, Olsson KM, Opitz CF, Rosenkranz S, Seyfarth HJ, Warnke C, Wiedenroth C, Ghofrani HA, Ewert R. J Heart Lung Transplant. 2018 Oct;37(10):1235-1244 4. Tetraspanin CD82 affects migration, attachment and invasion of rheumatoid arthritis synovial fibroblasts. Neumann E, Schwarz MC, Hasseli R, Hülser ML, Classen S, Sauerbier M, Rehart S, Mueller-Ladner U. Ann Rheum Dis. 2018 Nov;77(11):1619-1626

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Labormedizin & Krankenhaushygiene Direktorin: Dr. med. K. Madlener

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Labormedizin & Krankenhaushygiene

Publikationen 2018 Originalarbeiten & Übersichtsarbeiten 1. Brixner V, Kiessling AH, Madlener K, Müller MM, Leibacher J, Dombos S, Weber I, Pfeiffer HU,

Geisen C, Schmidt M, Henschler R, North A, Huang N, Mufti N, Erickson A, Ernst C, Rico S, Benjamin RJ, Corash LM, Seifried E. Red blood cells treated with the amustaline (S-303) pathogen reduction system: a transfusion study in cardiac surgery. Transfusion. 2018 Apr;58(4):905-916.

2. Madlener K. Das Antiphospholipid-Syndrom – Eine interdisziplinäre Herausforderung. Akt Rheumatol 2018; 43(06): 456-462J Am Coll Cardiol. 2017 Nov 28;70(21):2636-2648.

3. Schindewolf M, Steindl J Beyer-Westendorf J, Schellong S, Dohmen PM, Brachmann J, Madlener K, Pötzsch B, Klamroth R, Hankowitz J, Banik N, Eberle S, Müller MM, Kropff S, Lindhoff-Last E. Use of Fondaparinux Off-Label or Approved Anticoagulants for Management of Heparin-Induced Thrombocytopenia. Volume 70, Issue 21, November 2017

4. Reply: Fondaparinux and Direct Oral Anticoagulants: Promising Anticoagulant for Management of Heparin-Induced Thrombocytopenia. Volume 71, Issue 15, April 2018

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Labormedizin & Krankenhaushygiene

42

Rehabilitationszentrum Rehabilitation Ärztlicher Leiter: Prof. Dr. med. T. Mengden

Psychokardiologie Ärztliche Leiterin: Prof. Dr. med. B. Hamann

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Rehabilitationszentrum Rehabilitation Ärztlicher Leiter: Prof. Dr. med. T. Mengden

Psychokardiologie Ärztliche Leiterin: Prof. Dr. med. B. Hamann

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Psychokardiologie

Publikationen 2018 1. Albus C, Waller C, Fritzsche K, Gunold H, Haass M, Hamann B, Kindermann I, Köllner V, Leithäuser B,

Marx N, Meesmann M, Michal M, Ronel J, Scherer M, Schrader V, Schwaab B, Weber CS, Herrmann-Lingen C. Bedeutung von psychosozialen Faktoren in der Kardiologie – Update 2018 Positionspapier der Deutschen Gesellschaft für Kardiologie. Kardiologe 2018; 12:312

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Kerckhoff-Klinik Forschungsgesellschaft mbH Med. Direktor: Prof. Dr. med. V. Mitrovic

48

Kerckhoff-Klinik Forschungsgesellschaft mbH

Publikationen 2018

Originalarbeiten

1. Rieth AJ, Richter MJ, Berkowitsch A, Frerix M, Tarner IH, Mitrovic V, Hamm CW. Intravenous sildenafil acutely improves hemodynamic response to exercise in patients with connective tissue disease. PLoS One. 2018 Sep 20; 13(9):e0203947. doi: 10.1371/journal.pone.0203947.eCollection 2018.

2. Mitrovic V, Forssmann WG, Schnitker J, Felix SB. Randomized double-blind clinical studies of ulari-tide and other vasoactive substances in acute decompensated heart failure: a systematic review and meta-analysis. ESC Heart Fail. 2018 Dec;5(6): 1023-1034. doi: 10.1002/ehf2.12349. Epub 2018 Sep 24.