SKRIPSI

DEVI SESYARANI

UJI AKTIVITAS SENYAWA DALAM TANAMAN

BERPOTENSI UNTUK PENGOBATAN ASAM

URAT SECARA IN SILICO

(Pada Nigella sativa Semen Sebagai Antiinflamasi

dan Orthosiphon stamineus Folium Sebagai

Antihiperurisemia)

PROGRAM STUDI FARMASI

FAKULTAS ILMU KESEHATAN

UNIVERSITAS MUHAMMADIYAH MALANG

2018

KATA PENGANTAR

Assalamu’alaikum,Wr.Wb.

Puji syukur kehadirat Allah SWT, atas limpahan Rahmat dan Karunia-Nya

penulis dapat menyelasaikan penyusunan skripsi ini. Shalawat beserta salam

semoga senantiasa terlimpah curahkan kepada Nabi Muhammad SAW.

Penulisan skripsi ini diajukan untuk memenuhi salah satu syarat

memperoleh gelar Sarjana pada Program Studi Farmasi Fakultas Ilmu Kesehatan

Universitas Muhammadiya Malang. Judul yang diajukan adalah “ Uji Aktivitas

Senyawa dalam Tanaman Berpotensi untuk Pengobatan Asam Urat secara in

Silico”. Dalam penyusunan dan penulisan skripsi ini tidak terlepas dari bantuan,

bimbimngan serta dukungan dari berbagai pihak. Oleh karena itu dalam

kesempatan ini penulis dengan senang hati menyampaikan terimakasih kepada

yang terhormat:

1. Bapak Imam Hanitap dan Ibu Fatkhunisa atas jasa-jasanya, doa yang

selalu dipanjatkan dan cinta tulus serta ikhlas kepada penulis semenjak

kecil.

2. Ibu Sovia Aprina Basuki, S.Farm, M.Si., Apt. selaku dosen pembimbing I

yang selalu memeberi masukan dan nasehat selama mengerjakan skripsi

kepada penulis.

3. Ibu Engrid Juni Astuti M.Farm., Apt. selaku dosen pembimbing II yang

selalu bijak dalam memberikan bimbingan.

4. Bapak M. Artabah Muchlisin, M. Farm. Selaku dosen mata kuliah Kimia

Organik yang meluangkan waktu untuk memberikan bimbingan serta

mengarahkan penulis selama pengerjaan skripsi tanpa balasan apapun.

5. Saudara-saudara tercinta yang telah banyak memberikan bantuan baik

secara moril maupun materiil demi kelancaran penyusunan skripsi ini.

6. Ibu Anjar Wati yang selalu memberikan motivasi dan semangat kepada

penulis dalam mengapai cita-cita.

7. Teman-teman seperjuangan dan khususnya Hestining Puspa Weni ,Retno

Ayu Larasati, Khoridatur Rahma, Mahya, dan Safrinda Eka Damayanti

yang memberikan semangat untuk mengerjakan skripsi.

DAFTAR LAMPIRAN

Lampiran Halaman

1. Daftar Riwayat Hidup ............................................................................. 64 2. Surat Pernyataan..................................................................................... 65 3. Macam-Macam Senyawa Tumbuhan Uji ............................................... 66 4. Interaksi Senyawa……………………………………………………... 81 5. Residu Asam Amino yang Terikat pada Senyawa…………………….. 123 6. Hasil Uji Statistika One Way ANOVA………………………………... 132

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