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Reference 1. Bostwick JM, Pankratz VS. Affective disorders and suicide risk: A re-examination. American Journal of Psychiatry 2000; 1925 1932. 2. Goodwin FK, Jamison KR. Manic-depressive illness. New York: Oxford University Press; 1990. 3. Axelsson R, Lagerkvist-Briggs M. Factors predicting suicide in psychotic patients. European Archives of Psychiatry and Clinical Neuroscience1992; 241: 259 266. 4. Rihmer Z, Belso N, Kiss K. Strategies for suicide prevention. Curr Opin Psychiatry 2002; 83 87. 5. Malone K M, Oquendo MA, Haas GL, Ellis S P, Li S, Mann JJ. Protective factors against suicidal acts in major depression: Reasons for living. American Journal of Psychiatry 2000; 157: 1084 108. 6. Burton CZ, Vella L, Weller JA, Twamley EW. Differential Effects of Executive Functioning on Suicide Attempts. Journal of Neuropsychiatry and Clinical Neurosciences 2011; 173-179. 7. Mayberg HS. Modulating dysfunctional limbic-cortical circuits in depression: towards development of brain based algorithms for diagnosis and optimized treatment. British Medical Bulletin 2003; 193 207. 8. Price JL, Drevets, WC. Neurocircuitry of mood disorders. Neuropsychopharmacology 2010; 216-192. 9. Hickie I, Naismith S, Ward PB, Turner K, Scott E, Mitchell P, et al. Reduced hippocampal volumes and memory loss in patients with early- and late-onset depression. British Journal of Psychiatry 2005;197-202. 10. Heiden A, Kettenbach J, Fischer P, Schein B, Ba-Ssalamah A, Frey R, et al. White matter hyperintensities and chronicity of depression. Journal of Psychiatry Research 2005; 39:285293. 11. Li L, Ma N, Li Z, Tan T, Liu J, Gong G, et al. Prefrontal white matter abnormalities in youngadult with major depressive disorder: a diffusion tensor imaging study. Brain Research 2007128-1168:124. 12.Ballmaier M, Narr KL, Toga AW, Elderkin-Thompson V, Thompson PM, Hamilton L, et al. Hippocampal morphology and distinguishing late-onset from early-onset elderly depression. American Journal of Psychiatry 2008; 165: 229-37. 13.Ries ML , Wichmann A, Bendlin BB, Johnson SC. Posterior cingulate and lateral parietal gray matter volume in older adults with depressive symptoms. Brain Imaging Behav 2009; 3: 233 239. 14. Koolschijn PC, van- Haren NE, Lensvelt-Mulders GJ, Hulshoff Pol HE, Kahn RS. Brain volume abnormalities in major depressive disorder: a meta-analysis of magnetic resonance imaging studies. Hum Brain Mapp 2009; 30:3719 3735.

15. Kempton MJ, Salvador Z, Munafo MR, Geddes JR, Simmons A, Frangou S, Williams SC. Structural neuroimaging studies in major depressive disorder: meta-analysis and comparison with bipolar disorder. Archives of General Psychiatry 2011; 68: 675

690

16. Pu S, Yamada T, Yokoyama K, Matsumura H, Kobayashi H, Sasaki N, et al. A multi-channel near-infrared spectroscopy study of prefrontal cortex activation during working memory task in major depressive disorder. Neuroscience Research 2011 ; 70:91 97. 17. Shenal BV, Harrison D W, Demaree HA. The neuropsychology of depression: A literature review and preliminary model. Neuropsychology Review 2003; 33 42. 18. Schatzberg A F. Major depression: Causes or effects? American Journal of Psychiatry 2002; 11077 1079. 19. Bearden CE, Hoffman KM, Cannon TD. The neuropsychology and neuroanatomy of bipolar affective disorder: a critical review. Bipolar Disord 2001; 106:151 153. 20. Harvey PO, Bastard GL, Pochon JB, Levy R, Allilaire JF, Dubois B, et al. Executive functions and updating of the contents of working memory in unipolar depression. Journal of Psychiatric Research 2004; 567 576. 21. Kampf-Sherf O, Zlotogorski Z, Gilboa A, Speedie L, Lereya J, Rosca P, et al. Neuropsychological functioning in major depression and responsiveness to selective serotonin reuptake inhibitors antidepressants. Journal of Affective Disorders 2004; 82: 453 459. 22. Fossati P, Amar G, Raoux N, Ergis AM, Allilaire JF. Executive functioning and verbal memory in young patients with unipolar depression and schizophrenia. Psychiatry Research 1999; 89: 171 187. 23. Burt DB, Zembar M, Niederehe G. Depression and memory impairment: a meta-analysis of the association, its pattern and specificity. Psychol Bull 1995; 117:285 305. 24.Keilp JG, Sackeim HA, Brodsky BS, Oquendo MA, Malone KM, Mann JJ. Neuropsychological dysfunction in depressed suicide attempters. Am J Psychiatry 2001; 158:735 741. 25. Keilp JG, Gorlyn M, Oquendo MA, Burke AK, Mann JJ. Attention deficit in depressed suicide attempters. Psychiatry research 2008; 159:7-17. 26. Jollan tF, Bellivier F, Leboyer M, Astruc B, Torres S, Verdier R, et al. Impaired decision-making in suicide attempters. Am J Psychiatry 2005; 162:304 310. 27. Keilp JG, Gorlyn M, Russell M, Oquendo MA, Burke AK, Harkavy-Friedman J, et al. Neuropsychological function and suicidal behavior: attention control, memory and executive dysfunction in suicide attempt. Psychological medicine 2013; 43: 539-551. 28. Miranda R, Gallagher M, Bauchner B, Vaysman R, Marroqu?n B. Cognitive inflexibility as a prospective predictor of suicidal ideation among young adults with a suicide attempt history. Depression and anxiety 2012; 29:180-186. 29. Westheide J, Quednow BB, Kuhn KU, Hoppe C, Cooper-Mahkorn D, Hawellek B, et al. Executive performance of depressed suicide attempters: the role of suicidal ideation. European Archives of Psychiatry and Clinical Neuroscience 2008; 258:414 421. 30. Marzuk PM, Hartwell N, Leon AC, Portera L. Executive functioning in depressed patients with suicidal ideation. Acta Psychiatrica Scandinavica 2005; 112:294 301. 31. Potkin SG, Anand R, Alphs L, Fleming K. Neurocognitive performance does not correlate with suicidality in schizophrenic and schizoaffective patients at risk for suicide. Schizophr Res 2003; 59:59 66. 32. King DA, Conwell Y, Cox C, Henderson RE, Denning DG, Caine ED. A neuropsychological comparison of depressed suicide attempters and nonattempters. J Neuropsychiatry Clin Neurosci 2000; 12: 64 70.

33. Nangle JM, Clarke S, Morris DW, Schwaiger S, McGhee KA, Kenny N, et al. Neurocognition and suicidal behavior in an Irish population with major psychotic disorders. Schizophr Res 2006; 196 200 34. Kim CH, Jayathilake K, Meltzer HY. Hopelessness, neurocognitive function, and insight in schizophrenia: relationship to suicidal behaviour. Schizophr Res 2003; 60:71 80. 35. Steer RA, Beck AT, Modifying the Beck, AT. Modifying the Beck Depression Inventory: A reply to Vredenburg , Krames , & Flett. Psychological Reports 1985;57: 625-626. 36. Dabson S, Mohammadkhani P. Psychometric property of Depression Inventory-2 in depression people who are in relative remission. Journal of rehabilitation. 2007; 8: 80-86. 37. Klee SH, Garfinkel BD.The computerized continuous performance task: A new measure inattention. Journal of Abnormal Child Psychology 1983; 11: 487 496. 38. Hadianfar H, Najarian B, Shokrkon H, Mehrabizadeie-Honarmand M. provision and making of Persian form of continues performance test. Journal of psychology. 2000; 4: 388-404. 39. Shagholian M, Azad-falah P, Fathie-Ashtiani A, Khodadi M. Desining softwar version of Wisconsin Card Sorting Test: base of theory, Procedure of making and psychometric propertys. Journal of clinical psychology 2011; 4: 112-133. 40. Gansler DA, Covail S, McGrath N. Measures of prefrontal dysfunction after closed head injury. Brain and Cognition .1996; 30: 194 204. 41. Mashhadi A, Rasoolzade-Tabatabai K, Azad Fallah P, Soltanifar A. Comparing of response inhibitation and interference of control in children who suffer from attention deficit and hyperactivity disorder. Journal of psychology 2009; 1: 37-50. 42. Lyche P, Jonassen R, Stiles TC, Ulleberg P, Landro, NI. Cognitive Control Functions in Unipolar Major Depression with and without Co-Morbid Anxiety Disorder. Front Psychiatry. 2010; 1: 149. 43.Den Hartog HM, Derix MMA, Van Bemmel AL, Kremer B, Jolles J. Cognitive functioning in young and middle-aged unmedicated out-patients with major depression: testing the effort and cognitive speed hypotheses. Psychological Medicine 2003; 33: 14431451. 44. Ottowitz W, Dougherty D, Savage C. The neural network basis for abnormalities of attention and executive function in major depressive disorder: implications for application of the medical disease model to psychiatric disorders. Harv Rev Psychiatry 2002; 10:86 99. 45.Salthouse TA. The processing-speed theory of adult age differences in cognition. Psychological Review 1998; 103: 403

428. 46.Kessing, LV. Cognitive impairment in the euthymic phase of affective disorder. Psychological Medicine 1998; 28: 1027 1038. 47.Driscoll HC, Basinski J, Mulsant BH, Butters MA, Dew MA, Houck PR, Reynolds CF. Late-onset major depression: Clinical and treatment response variability. International Journal of Geriatric Psychiatry 2005; 20: 661 667. 48. Grant MM, Thase ME, Sweeney JA. Cognitive disturbance in outpatient depressed younger adults: Evidence of modest impairment. Biological Psychiatry 2001; 5:, 35 43. 49. Heeringen, K. V. (2001). Understanding suicidal behavior: The suicidal process approach to research, treatment and prevention. New York: John Wiley & Son, Inc. 50. levenson M, Neuringer C. Problem solving behavior in suicidal adolescents. Journal of consulting and clinical psychology 1971;37: 433-436.